LOCUS       DAVKXA010000001       105040 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKXA010000001 DAVKXA010000000
VERSION     DAVKXA010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 105040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.001"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            20..355
                     /locus_tag="VW883_000001"
     CDS             20..355
                     /locus_tag="VW883_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273213.1"
                     /translation="MGGILLLIGPFVLLGTAVNTAATTLNGGATAGAFSGVALLLNAL
                     KIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGWVGGILAIIGGSLFLA
                     TLKKFKSEE"
     gene            889..1581
                     /locus_tag="VW883_000002"
     CDS             889..1581
                     /locus_tag="VW883_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0273214.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1634..4045
                     /locus_tag="VW883_000003"
     CDS             1634..4045
                     /locus_tag="VW883_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0273215.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYGFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSEANKINLWARLGDGNRAHKLLAEQLKTSTLQNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4295..4996
                     /locus_tag="VW883_000004"
     CDS             4295..4996
                     /locus_tag="VW883_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273216.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNSDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            4998..7706
                     /locus_tag="VW883_000005"
     CDS             4998..7706
                     /locus_tag="VW883_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0273217.1"
                     /translation="MIKRQTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7802..8293)
                     /gene="tpx"
                     /locus_tag="VW883_000006"
     CDS             complement(7802..8293)
                     /gene="tpx"
                     /locus_tag="VW883_000006"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0273218.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8416..9345)
                     /gene="psaA"
                     /locus_tag="VW883_000007"
     CDS             complement(8416..9345)
                     /gene="psaA"
                     /locus_tag="VW883_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0273219.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9377..10225)
                     /locus_tag="VW883_000008"
     CDS             complement(9377..10225)
                     /locus_tag="VW883_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0273220.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10222..10944)
                     /locus_tag="VW883_000009"
     CDS             complement(10222..10944)
                     /locus_tag="VW883_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0273221.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11235..13127
                     /gene="pepO"
                     /locus_tag="VW883_000010"
     CDS             11235..13127
                     /gene="pepO"
                     /locus_tag="VW883_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0273222.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13250..13879)
                     /locus_tag="VW883_000011"
     CDS             complement(13250..13879)
                     /locus_tag="VW883_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0273223.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(14219..14461)
                     /locus_tag="VW883_000012"
     CDS             complement(14219..14461)
                     /locus_tag="VW883_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273224.1"
                     /translation="MMRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            14872..17094
                     /locus_tag="VW883_000013"
     CDS             14872..17094
                     /locus_tag="VW883_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0273225.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17124..17567
                     /locus_tag="VW883_000014"
     CDS             17124..17567
                     /locus_tag="VW883_000014"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0273226.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17606..18020)
                     /locus_tag="VW883_000015"
                     /pseudo
     CDS             complement(17606..18020)
                     /locus_tag="VW883_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18039..18452)
                     /locus_tag="VW883_000016"
     CDS             complement(18039..18452)
                     /locus_tag="VW883_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273227.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18554..19231)
                     /locus_tag="VW883_000017"
     CDS             complement(18554..19231)
                     /locus_tag="VW883_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0273228.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTLLFGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMDLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSNKEY"
     gene            complement(19430..20080)
                     /locus_tag="VW883_000018"
     CDS             complement(19430..20080)
                     /locus_tag="VW883_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0273229.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            20192..21034
                     /locus_tag="VW883_000019"
     CDS             20192..21034
                     /locus_tag="VW883_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0273230.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLNQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21110..21547
                     /locus_tag="VW883_000020"
     CDS             21110..21547
                     /locus_tag="VW883_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0273231.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21615..21917
                     /locus_tag="VW883_000021"
     CDS             21615..21917
                     /locus_tag="VW883_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273232.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(22008..23081)
                     /locus_tag="VW883_000022"
     CDS             complement(22008..23081)
                     /locus_tag="VW883_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0273233.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            23237..23914
                     /locus_tag="VW883_000023"
     CDS             23237..23914
                     /locus_tag="VW883_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0273234.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            23907..24881
                     /locus_tag="VW883_000024"
     CDS             23907..24881
                     /locus_tag="VW883_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0273235.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(24930..26873)
                     /gene="thrS"
                     /locus_tag="VW883_000025"
     CDS             complement(24930..26873)
                     /gene="thrS"
                     /locus_tag="VW883_000025"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0273236.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(26931..27107)
                     /locus_tag="VW883_000026"
     CDS             complement(26931..27107)
                     /locus_tag="VW883_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0273237.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(27114..27254)
                     /locus_tag="VW883_000027"
     CDS             complement(27114..27254)
                     /locus_tag="VW883_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0273238.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            28124..28753
                     /locus_tag="VW883_000028"
     CDS             28124..28753
                     /locus_tag="VW883_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0273239.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKEHISLLEK"
     gene            28894..29163
                     /gene="rpsO"
                     /locus_tag="VW883_000029"
     CDS             28894..29163
                     /gene="rpsO"
                     /locus_tag="VW883_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0273240.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            29978..30592
                     /locus_tag="VW883_000030"
     CDS             29978..30592
                     /locus_tag="VW883_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0273241.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(30884..31633)
                     /locus_tag="VW883_000031"
     CDS             complement(30884..31633)
                     /locus_tag="VW883_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0273242.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            31766..34102
                     /locus_tag="VW883_000032"
     CDS             31766..34102
                     /locus_tag="VW883_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV0273243.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            34204..34881
                     /locus_tag="VW883_000033"
     CDS             34204..34881
                     /locus_tag="VW883_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0273244.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            34868..35665
                     /locus_tag="VW883_000034"
     CDS             34868..35665
                     /locus_tag="VW883_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0273245.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            35682..36785
                     /locus_tag="VW883_000035"
     CDS             35682..36785
                     /locus_tag="VW883_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0273246.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVAVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            37086..38105
                     /gene="galE"
                     /locus_tag="VW883_000036"
     CDS             37086..38105
                     /gene="galE"
                     /locus_tag="VW883_000036"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0273247.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            38107..39072
                     /locus_tag="VW883_000037"
     CDS             38107..39072
                     /locus_tag="VW883_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0273248.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(39123..39329)
                     /locus_tag="VW883_000038"
     CDS             complement(39123..39329)
                     /locus_tag="VW883_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0273249.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            39381..39857
                     /locus_tag="VW883_000039"
     CDS             39381..39857
                     /locus_tag="VW883_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0273250.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            39866..40537
                     /locus_tag="VW883_000040"
     CDS             39866..40537
                     /locus_tag="VW883_000040"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0273251.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            40668..41006
                     /locus_tag="VW883_000041"
     CDS             40668..41006
                     /locus_tag="VW883_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0273252.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            41009..41638
                     /locus_tag="VW883_000042"
     CDS             41009..41638
                     /locus_tag="VW883_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0273253.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTIFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            41879..43030
                     /locus_tag="VW883_000043"
     CDS             41879..43030
                     /locus_tag="VW883_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0273254.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            43342..44091
                     /gene="truA"
                     /locus_tag="VW883_000044"
     CDS             43342..44091
                     /gene="truA"
                     /locus_tag="VW883_000044"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0273255.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            44081..44854
                     /locus_tag="VW883_000045"
     CDS             44081..44854
                     /locus_tag="VW883_000045"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0273256.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            44832..45293
                     /locus_tag="VW883_000046"
     CDS             44832..45293
                     /locus_tag="VW883_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0273257.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            45520..46857
                     /locus_tag="VW883_000047"
                     /pseudo
     CDS             45520..46857
                     /locus_tag="VW883_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(46985..47188)
                     /locus_tag="VW883_000048"
     CDS             complement(46985..47188)
                     /locus_tag="VW883_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273258.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(47181..48263)
                     /locus_tag="VW883_000049"
     CDS             complement(47181..48263)
                     /locus_tag="VW883_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0273259.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(48389..49171)
                     /locus_tag="VW883_000050"
     CDS             complement(48389..49171)
                     /locus_tag="VW883_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0273260.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(49171..50514)
                     /locus_tag="VW883_000051"
     CDS             complement(49171..50514)
                     /locus_tag="VW883_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0273261.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILEAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(50613..51929)
                     /locus_tag="VW883_000052"
     CDS             complement(50613..51929)
                     /locus_tag="VW883_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0273262.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGDLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            52122..53348
                     /locus_tag="VW883_000053"
     CDS             52122..53348
                     /locus_tag="VW883_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0273263.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            53547..55121
                     /locus_tag="VW883_000054"
     CDS             53547..55121
                     /locus_tag="VW883_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0273264.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LNEKQTGFVIRNKGDK"
     gene            55386..56174
                     /gene="codY"
                     /locus_tag="VW883_000055"
     CDS             55386..56174
                     /gene="codY"
                     /locus_tag="VW883_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0273265.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            56174..56749
                     /locus_tag="VW883_000056"
     CDS             56174..56749
                     /locus_tag="VW883_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0273266.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            56830..56915
                     /locus_tag="VW883_000057"
     tRNA            56830..56915
                     /locus_tag="VW883_000057"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56864..56866,aa:Leu,seq:aag)
     gene            57198..58328
                     /gene="ugpC"
                     /locus_tag="VW883_000058"
     CDS             57198..58328
                     /gene="ugpC"
                     /locus_tag="VW883_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0273267.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(58475..58621)
                     /locus_tag="VW883_000059"
     CDS             complement(58475..58621)
                     /locus_tag="VW883_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273268.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            58829..59587
                     /locus_tag="VW883_000060"
     CDS             58829..59587
                     /locus_tag="VW883_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0273269.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            59675..60187
                     /locus_tag="VW883_000061"
     CDS             59675..60187
                     /locus_tag="VW883_000061"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0273270.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKTTIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            60369..61313
                     /locus_tag="VW883_000062"
     CDS             60369..61313
                     /locus_tag="VW883_000062"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0273271.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            61322..61999
                     /locus_tag="VW883_000063"
     CDS             61322..61999
                     /locus_tag="VW883_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0273272.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            62097..62855
                     /locus_tag="VW883_000064"
     CDS             62097..62855
                     /locus_tag="VW883_000064"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0273273.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            62893..64397
                     /gene="lytC"
                     /locus_tag="VW883_000065"
                     /pseudo
     CDS             62893..64397
                     /gene="lytC"
                     /locus_tag="VW883_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            64893..65411
                     /locus_tag="VW883_000066"
     CDS             64893..65411
                     /locus_tag="VW883_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0273274.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            65541..66047
                     /locus_tag="VW883_000067"
     CDS             65541..66047
                     /locus_tag="VW883_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0273275.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            66047..66217
                     /locus_tag="VW883_000068"
     CDS             66047..66217
                     /locus_tag="VW883_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273276.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            66249..67481
                     /gene="clpX"
                     /locus_tag="VW883_000069"
     CDS             66249..67481
                     /gene="clpX"
                     /locus_tag="VW883_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0273277.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            67490..68077
                     /locus_tag="VW883_000070"
     CDS             67490..68077
                     /locus_tag="VW883_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0273278.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            68088..68468
                     /locus_tag="VW883_000071"
     CDS             68088..68468
                     /locus_tag="VW883_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0273279.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            68520..69410
                     /gene="rapZ"
                     /locus_tag="VW883_000072"
     CDS             68520..69410
                     /gene="rapZ"
                     /locus_tag="VW883_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0273280.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            69407..70384
                     /locus_tag="VW883_000073"
     CDS             69407..70384
                     /locus_tag="VW883_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0273281.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIHPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            70381..71292
                     /gene="whiA"
                     /locus_tag="VW883_000074"
     CDS             70381..71292
                     /gene="whiA"
                     /locus_tag="VW883_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0273282.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(71380..72507)
                     /locus_tag="VW883_000075"
     CDS             complement(71380..72507)
                     /locus_tag="VW883_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0273283.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIQSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(72786..73736)
                     /locus_tag="VW883_000076"
     CDS             complement(72786..73736)
                     /locus_tag="VW883_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEV0273284.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPSDWHRNEPKV"
     gene            complement(73885..74676)
                     /locus_tag="VW883_000077"
     CDS             complement(73885..74676)
                     /locus_tag="VW883_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0273285.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAVIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            complement(74920..75609)
                     /locus_tag="VW883_000078"
     CDS             complement(74920..75609)
                     /locus_tag="VW883_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV0273286.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            75816..75995
                     /locus_tag="VW883_000079"
     CDS             75816..75995
                     /locus_tag="VW883_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273287.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKRSRTTLTERR"
     gene            76000..76215
                     /locus_tag="VW883_000080"
     CDS             76000..76215
                     /locus_tag="VW883_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273288.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            76247..76447
                     /locus_tag="VW883_000081"
     CDS             76247..76447
                     /locus_tag="VW883_000081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273289.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(76846..77037)
                     /locus_tag="VW883_000082"
     CDS             complement(76846..77037)
                     /locus_tag="VW883_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273290.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            77156..77299
                     /locus_tag="VW883_000083"
     CDS             77156..77299
                     /locus_tag="VW883_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273291.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            77378..77650
                     /locus_tag="VW883_000084"
     CDS             77378..77650
                     /locus_tag="VW883_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273292.1"
                     /translation="MEVVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            77647..77841
                     /locus_tag="VW883_000085"
     CDS             77647..77841
                     /locus_tag="VW883_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273293.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            77838..78029
                     /locus_tag="VW883_000086"
     CDS             77838..78029
                     /locus_tag="VW883_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273294.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            78041..78382
                     /locus_tag="VW883_000087"
     CDS             78041..78382
                     /locus_tag="VW883_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273295.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYFNHTQALTELVDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            78383..78613
                     /locus_tag="VW883_000088"
     CDS             78383..78613
                     /locus_tag="VW883_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273296.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            78627..79349
                     /locus_tag="VW883_000089"
     CDS             78627..79349
                     /locus_tag="VW883_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0273297.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGVSLTEKQIKSYRRNNNLHSGLTG
                     RFEKDQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            79342..79824
                     /locus_tag="VW883_000090"
     CDS             79342..79824
                     /locus_tag="VW883_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV0273298.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQAAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            79824..80183
                     /locus_tag="VW883_000091"
     CDS             79824..80183
                     /locus_tag="VW883_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273299.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            80183..80668
                     /locus_tag="VW883_000092"
     CDS             80183..80668
                     /locus_tag="VW883_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273300.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNEKSKDNSVAETIAYIQLCYPEAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            80631..81824
                     /locus_tag="VW883_000093"
     CDS             80631..81824
                     /locus_tag="VW883_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV0273301.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            81843..82160
                     /locus_tag="VW883_000094"
     CDS             81843..82160
                     /locus_tag="VW883_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273302.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            82160..82987
                     /locus_tag="VW883_000095"
     CDS             82160..82987
                     /locus_tag="VW883_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0273303.1"
                     /translation="MAFTLPVNKPQVPVDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEPAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            83007..83513
                     /locus_tag="VW883_000096"
     CDS             83007..83513
                     /locus_tag="VW883_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273304.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDDDDLPF"
     gene            83686..84507
                     /locus_tag="VW883_000097"
     CDS             83686..84507
                     /locus_tag="VW883_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV0273305.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            84510..85853
                     /locus_tag="VW883_000098"
     CDS             84510..85853
                     /locus_tag="VW883_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0273306.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPIMADSKQQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            86146..86301
                     /locus_tag="VW883_000099"
     CDS             86146..86301
                     /locus_tag="VW883_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273307.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            86298..86993
                     /locus_tag="VW883_000100"
     CDS             86298..86993
                     /locus_tag="VW883_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0273308.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREVWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELENAKIGW
                     VFDCEGFEIEEVE"
     gene            87151..87411
                     /locus_tag="VW883_000101"
     CDS             87151..87411
                     /locus_tag="VW883_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV0273309.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            87411..87869
                     /locus_tag="VW883_000102"
     CDS             87411..87869
                     /locus_tag="VW883_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273310.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            87917..87985
                     /locus_tag="VW883_000103"
                     /pseudo
     CDS             87917..87985
                     /locus_tag="VW883_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            87982..88419
                     /locus_tag="VW883_000104"
     CDS             87982..88419
                     /locus_tag="VW883_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273311.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            88416..88787
                     /locus_tag="VW883_000105"
     CDS             88416..88787
                     /locus_tag="VW883_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273312.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFVR"
     gene            88857..89279
                     /locus_tag="VW883_000106"
     CDS             88857..89279
                     /locus_tag="VW883_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0273313.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWIDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRLINKLKNPKSRSILRVTYITK
                     MYVDDICDKMEISRTTFYTWRNMAISELNEVLERMELN"
     gene            89365..89447
                     /locus_tag="VW883_000107"
     tRNA            89365..89447
                     /locus_tag="VW883_000107"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:89396..89398,aa:Tyr,seq:gta)
     gene            89697..90176
                     /locus_tag="VW883_000108"
     CDS             89697..90176
                     /locus_tag="VW883_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0273314.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQT
                     LISIGELGQTITDINVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            90154..91452
                     /locus_tag="VW883_000109"
     CDS             90154..91452
                     /locus_tag="VW883_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0273315.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYSWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYTIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            91464..92933
                     /locus_tag="VW883_000110"
     CDS             91464..92933
                     /locus_tag="VW883_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0273316.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTEGSHLKKLKSYYL
                     GEHAILKHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQE
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            92842..94392
                     /locus_tag="VW883_000111"
     CDS             92842..94392
                     /locus_tag="VW883_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV0273317.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLMSLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLNYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDVKNEIQDYKKSDKTVSRYNTPKLFSDVSNAWDEIGRGGLSKEQLV
                     DLLESEYELGNFSSDIAKLIGVSSAYIDVSSLATSLVRHGQQYSLDEFMLIKEAVQKP
                     YLILDNSERVEKSIISYVKIPNKDKVIMEAVMVPRDEMLVIHFNKVGIRQVKKNEKNM
                     STLYKKGK"
     gene            94543..94716
                     /locus_tag="VW883_000112"
     CDS             94543..94716
                     /locus_tag="VW883_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273318.1"
                     /translation="MDTARIGITNVEFSGTGENDSATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            94861..95073
                     /locus_tag="VW883_000113"
     CDS             94861..95073
                     /locus_tag="VW883_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273319.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            95243..95827
                     /locus_tag="VW883_000114"
     CDS             95243..95827
                     /locus_tag="VW883_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0273320.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            95834..96679
                     /locus_tag="VW883_000115"
     CDS             95834..96679
                     /locus_tag="VW883_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0273321.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            96691..96873
                     /locus_tag="VW883_000116"
     CDS             96691..96873
                     /locus_tag="VW883_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0273322.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            96863..97051
                     /locus_tag="VW883_000117"
     CDS             96863..97051
                     /locus_tag="VW883_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273323.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEEIFPKPEFLEED"
     gene            97053..97364
                     /locus_tag="VW883_000118"
     CDS             97053..97364
                     /locus_tag="VW883_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0273324.1"
                     /translation="MSIELLKKLTGEEDTQLLMLFQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            97345..97683
                     /locus_tag="VW883_000119"
     CDS             97345..97683
                     /locus_tag="VW883_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273325.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            97658..98173
                     /locus_tag="VW883_000120"
     CDS             97658..98173
                     /locus_tag="VW883_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0273326.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            98170..98538
                     /locus_tag="VW883_000121"
     CDS             98170..98538
                     /locus_tag="VW883_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273327.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            98541..98954
                     /locus_tag="VW883_000122"
     CDS             98541..98954
                     /locus_tag="VW883_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0273328.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            98959..99339
                     /locus_tag="VW883_000123"
     CDS             98959..99339
                     /locus_tag="VW883_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273329.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            99378..99728
                     /locus_tag="VW883_000124"
     CDS             99378..99728
                     /locus_tag="VW883_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273330.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            99715..103368
                     /locus_tag="VW883_000125"
     CDS             99715..103368
                     /locus_tag="VW883_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273331.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDVAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSTPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISSICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTNMFQKAWTGLTNIFSKLGSWFGERWADVTNALSSVSNWFGE
                     MFTNAYNAVKDAFSSIGDFFKGVWDTVKSIFVNAGQMVGEAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGVSPQGGFSGDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            103377..103727
                     /locus_tag="VW883_000126"
     CDS             103377..103727
                     /locus_tag="VW883_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273332.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGELSQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGNRTAPRYTFTEK
                     FKPWSGAKFNLVER"
     gene            103732..>105040
                     /locus_tag="VW883_000127"
     CDS             103732..>105040
                     /locus_tag="VW883_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0273333.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGDYTSRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKHKAEEALRNAGASTLLAQEAKRI"
BASE COUNT        32005 a        19010 c        23822 g        30203 t
ORIGIN      
        1 tagtggtatc gtcggtcttg tgggaggaat tttacttctt attggtcctt ttgtcttgtt
       61 gggaacagcg gtaaacacag ctgctacaac tcttaatgga ggagctactg caggggcttt
      121 ttcaggtgta gccttactct tgaatgcctt gaagattgca aatcttgttc ttggtatcat
      181 tgctattgtt tactataaag gagataagcg tgtaggtgca gctccgtctg tactaatgat
      241 tgtttctggt ggagttagtc tcattccatt cttaggatgg gttgggggga ttcttgctat
      301 tatcggagga tctctattcc ttgcaacatt gaagaaattc aaatcagaag aataaaaggt
      361 attttagcat gaaaagaaca aaaagtttat cggtatagga gtagctctat tatctctttc
      421 tcttctagtt gcatgtggaa cataaagttc aaagaatact tcaacaagta atgatgagaa
      481 gacagtagca acatccaata gttcaaaaga aacaatcact ttcgatacac cggttgtaac
      541 agacgatgcg attgaatcaa tacgcactta tgcagattat atagatcttt ataaaaatat
      601 ttttgatgat tattttacta aagctgagga aggtttcaaa ggcacagcta tggaaaataa
      661 tgactcgttt actaaactaa aagagtcaac tcaaaaatta ttcgatgcgc agaaaaaaag
      721 gttaaataat gaagatagaa tagaaacaac caaaaacaat gtgattgcca aacattgtca
      781 aacagtcctt tcctttttgg ttttgactag cttttttgtg aaaaattgtg taaaatagaa
      841 tagataaacg aggggaaacc tcggaaaatt taaaggagaa tccatctaat ggtaaaattg
      901 gtttttgctc gccacggtga gtctgaatgg aacaaagcta accttttcac tggttgggct
      961 gatgttgatt tgtctgaaaa aggtacacaa caagcgattg acgctggtaa attgatcaaa
     1021 gaagctggta tcaaatttga ccaagcttac acttcagtat tgaaacgtgc tatcaaaaca
     1081 actaacttgg ctcttgaagc ttctgaccaa ttgtgggttc cagttgaaaa atcatggcgc
     1141 ttgaacgaac gtcactatgg tggtttgact ggtaaaaata aagctgaagc tgctgaacaa
     1201 tttggtgatg agcaagttca catctggcgt cgttcatacg atgtattgcc tccaaacatg
     1261 gaccgtgatg atgagcactc agctcacaca gaccgtcgtt acgcttcact tgacgactca
     1321 gttatcccag atgctgaaaa cttgaaagtg actttggaac gtgctcttcc attctgggaa
     1381 gataaaatcg ctccagctct taaagatggt aaaaacgtat tcgtaggagc tcacggtaac
     1441 tcaatccgtg cccttgtaaa acacatcaaa ggtttgtcag atgacgagat catggacgtg
     1501 gaaatcccta acttcccacc attggtattc gaattcgacg aaaaattgaa cgtcgtttct
     1561 gaatactacc ttggaaaata aaaaattgta agtctagaat tgatttctag gctttttatg
     1621 ttagtatgga agtatgataa ggaataaaaa acaagattat gtactggcct acaagcaacc
     1681 agcttcaacc acttacatgg gttgggaaga agaagcttta ccgataggca atggttcttt
     1741 aggagcaaaa gtatttggcc ttataggggc tgaacggatt caatttaatg aaaaaagtct
     1801 ctggtctgga ggtccacttc ctgatagttc agattatcag ggtggaaatc ttcaggatca
     1861 gtatggtttt ttagctgaga ttcggcaggc tttggagaag agagattaca atctggctaa
     1921 ggaactggct gagcagcacc taattgggcc aaaaacgagt caatatggga cctatctgtc
     1981 ttttggggat attcacattg agttcagcca gcaaggtacg actttgtctc aggtgacgga
     2041 ctatcagaga cagctgaata ttagtaaggc acttgcgacg acttcttatg tctataaggg
     2101 aacgcgattt gaacgtaaag cttttgcgag ttttccagat gatctcttga ttcaatgttt
     2161 tactaaggaa gggttggaaa ctctagattt tactatagaa ctatccttga cctgtgattt
     2221 ggcttctgat ggaaagtatg agcaggaaaa atctgattac aaggagtgta agttggatat
     2281 tactgattct catatcttga tgaagggaag agttaaggat aatgatctgc ggtttgctag
     2341 ttatctagct tgggaaacgg atggagatat tagagtttgg tcagataggg ttcagatatc
     2401 aggagccagt tatgccaatc tcttcttggc cgctaagacg gattttgccc aaaatcctgc
     2461 tagcaattat cgcaagaaac tagatttaga gcaacaggtg atagacttgg tggacacagc
     2521 taaagaaaag ggctataccc aattgaaatc aaggcatatc gaggactacc aagccttatt
     2581 ccagcgtgtt caattggatt tggaagctga tgttgacgca tccactacag atgatttgtt
     2641 aaaaaattat aagccacaag aagggcaggc tttggaggag ctgttcttcc agtatggacg
     2701 gtatttattg attagttcgt ccagagactg cccagatgct ctaccagcta acctacaggg
     2761 agtctggaat gcggtcgaca atcctccttg gaattcggac tatcacttaa atgtcaatct
     2821 gcagatgaat tattggccag cctatgttac caatctccta gagacggtct ttccagtcat
     2881 caactatgta gatgatttgc gtgtctatgg tcgtctagcg gctgtaaagt atgcaggaat
     2941 cgtctctcag aaaggtgagg agaatggttg gttggttcat actcaagcga ctccctttgg
     3001 ttggacggca cctggttggg attactattg gggttggtca ccagctgcca atgcgtggat
     3061 gatgcaaacc gtttatgaag cctattcatt ttatagggac caagactatc tcagggagaa
     3121 aatttatccc atgttgaggg aaacggttcg tttttggaat gcctttttac ataaggatca
     3181 gcaggcgcag cgttgggtgt cttctccgtc ttattcccca gaacatgggc cgatttcgat
     3241 tggcaatacc tatgaccaat ctctgatttg gcagttattt catgatttta ttcaggctgc
     3301 tcaggaattg ggactggatg aggacttgtt gactgaggtt aaggagaagt ctgatttact
     3361 aaatcctttg caaatcactc aatctggtcg aatcagggag tggtatgagg aggaagagca
     3421 gtattttcaa aatgagaaag tggaggccca gcatcggcac gcttcccatc tagtgggact
     3481 ctatcctggc aatctcttta gctacaaggg acaagagtat attgaagcgg cgcgtgctag
     3541 cctcaatgat cgtggagatg gcggcacagg ctggtccgag gctaataaga tcaatctctg
     3601 ggcgcgtttg ggagatggca atcgagccca taaattattg gcagagcagt taaagacatc
     3661 caccttgcaa aatctttggt gtagccatcc tccttttcag atagatggta attttggtgc
     3721 tactagtggc atggcagaaa tgttactcca gtctcatgca gcttatctgg tacctctagc
     3781 tgccctacct gatgcttggt caacaggttc tgtttcaggc ttaatggcac gtggacattt
     3841 tgaagtgagc atgagctggg aagataaaaa actcttacag ttgaccattt tatcaaggag
     3901 tggaggagat ttgcgagttt cttatccaga tattgagaag agtgtgatta aaatgaatca
     3961 agaaaaaata aaagcgaaat gcatggggaa agattgtatt tcggtggcaa cagcagaagg
     4021 tgatcttgtt caattttatt tttaagaaga tgttataagg cagtaatttg aaactgcctt
     4081 ttaataagga tttaagaata taggcagttt ccaactagtt gaaaaagcgt tataatgata
     4141 ataggaagta atactcaatg aaaatcaaag agcacaaaca aggaagctag ccgcaggttg
     4201 ctcaaaacag tgttttgagg ttgcagatgg aagctgacgt ggtttgaaga gagattttcg
     4261 aggagtataa tttgtttgat agagggtggg tctgatggct tatattgaga tgaaacactg
     4321 ttacaagcgt tatcaggttg gggacacgga gattgtggcc aatcgtgatg tgaattttga
     4381 gattgaaaag ggggaactgg ttattatcct tggtgcttca ggtgcaggca agtcaacagt
     4441 tcttaacctt cttgggggaa tggataccaa tgatgaaggg gaaatctgga ttgatggtgt
     4501 taatattgcg gattatagtt cccaccagcg caccaattac cgtagaaatg atgtggggtt
     4561 tgtttttcag ttttataatc tagtttctaa tctgacagct aaggaaaatg tggaactggc
     4621 ttctgaaatt gtgacagatg ccttgaattc tgatcaggtc ttgacagatg taggtctggc
     4681 tcatcgtcta aataactttc cagcccagct ttctggaggg gagcaacagc gagtctccat
     4741 tgcacgcgcg gtagccaaaa atcctaaaat tcttctttgt gatgaaccta ctggagcctt
     4801 ggattatcag acgggcaagc aggttttgaa aattctccaa gacatgtctc gtcaaaaggg
     4861 agcgacggtg atcatcgtga ctcataatgg agctttggcg cccattgctg atcgcgtgat
     4921 tcatatgcac gatgccagtg tcaaggatgt ggtgctcaac cagcatcctc aggatattga
     4981 cagtttggag tactagtatg atcaagcgac aaacttattg gaaggactta attcagtcct
     5041 tcacaggctc caaggggcgt tttttatcca tcttgatcct gatgatgttg ggatctctag
     5101 ccttagtagg cctcaaagta accagtccca acatggaggc gacagctaat gcttatttaa
     5161 caactgctca aaccttggat ttggcagtca tgtctaacta tggcttggat caagcagacc
     5221 aagaagaact aaaacagacg gagggcgcag aggtcgagtt tggctatttg acagatgtga
     5281 ctatggataa tgggcaggat gccattcgac tgtactccaa accagagcga atttcaacct
     5341 ttcagctaag aaagggacga cttcctcagt cagacaagga aatcgctttg gccactcatt
     5401 tgcaaggcca atacagcgtg ggacaggaga ttagttttaa agaaaaagaa gagggtcatt
     5461 cctctttaaa agaccatact tataccatta ctggttttgt ggattcggct gaaatcctct
     5521 cccagcgaga tatgggctac gcaggaagtg gaagtgggac tctgacagcc tatggggtga
     5581 ttttacctag tcagtttgat cagaaagtct acaatatagc tcgtttgaaa tatcaagatt
     5641 tagcaggttt aaatgccttt tcatcagctt atgaagaaaa atccaagcaa catcaggaag
     5701 accttgaaca aactttatca gataatggca aggtacgtct gcaacttttg aaaaaagaag
     5761 gacaagagtc tctagacaag gggcaagaga cccttgacaa ggctcagact aatttgcagg
     5821 aaggcaagcg tcgtttagca gctgctcaag ctcgtataca ggctcaagaa agtcaactag
     5881 ccttgtttcc tcaagttcag agagagcagg ctagtgctca acttacccaa gccaagcagg
     5941 aattgggcaa ggaagaggat aaactaaagc aagctgaaca aaatctagcc caagaaaagg
     6001 aaaaattaga aaaacatcag caagtcttgg acgatttggc ggagccaagg tatcaggtct
     6061 ataatcgtca gaccatgcca ggtggtcagg gctatcttat gtatagcaat gcttcatcca
     6121 gtattcgagc agtgggcaat atctttcctg tggtacttta tgccgtagca gccatggtga
     6181 cctttacgac catgactcgc tttgtagacg aagagcgaac tcatgcaggg atttttaagg
     6241 ccttgggtta tcgtagtaag gatattatcg ccaagtttct cctttatgga ctagtagctg
     6301 ggactgtcgg aacggctcta ggtagtatac ttggtcatta tttgctagcc agtgtaattt
     6361 caagtgtcat tacaaaaggc atggtggtgg gagaaactca gattcagttc tattggacct
     6421 atagcttact agcttttgtc ttgagcttgt tggcgagtgt gttaccagcc tatctggtgg
     6481 cttggaggga acttcatgac gaagcagccc agcttctact tcctaaacct cctgtcaaag
     6541 gagctaaaat cttattggag cgtatcggtt ttatctggcg tcgtctcagt tttactcata
     6601 aggtaacagc ccgcaacatc tttcgttata agcagagaat gttgatgaca atctttggtg
     6661 tggcaggttc tgtagctctg ctctttgcag gtttgggaat ccaatcttct gtagcaggag
     6721 ttccgtctaa acagtttcaa caaatccaac agtatcagat gcttgtctct gaaaatccta
     6781 gtgcgaccaa tcaggacaag gtagagctag cagaagtgtt gaaagggcag gagatactag
     6841 cctaccagaa aatctattct aaagcgctat acaaggattt caaaggcaaa gctggtcttc
     6901 aaaacattac tcttatgatg atagagaagg aagatttgac tccctttatc catcttcaac
     6961 atcatcagca ggagctgaca ttaaaagatg gcatcgttat tacagctaaa ctcgcccagc
     7021 tggcaggtgt caaggttggg cagactttag aaattgaagg taaggaacta aaggtcgctg
     7081 ctattactga gaactacgtt ggtcacttta tttatatgag tcaggctagc tatgagcaac
     7141 tttacggaca gctaccccaa gccaacactt atctggtctc attaagggat accagtgcaa
     7201 ctagtatcga aagtcaggcg ggcttgctta tgaatcaatc tgcggtgtcc agcgttgtcc
     7261 aaaatgcttc agccattcga ctcttcgact ctatcgctag ctcactcaat cagaccatga
     7321 ccatcttggt catcgtatcg gttctattag ctattgtcat cctttacaat ctgaccaata
     7381 tcaacgtagc tgagagaatc cgtgaactct ccactatcaa ggttcttggt tttcataata
     7441 atgaagtcac cctctacatt taccgtgaga cgattgtgct gtcccttgtg ggaatcgtac
     7501 ttggtctgat agctggtttc tatttacacc aatttttgat tcaaatgatt tcgcctgcga
     7561 ctattctctt ttatccgcag gtaggctggg aagtctatgt aatcccagtg gcagcagtaa
     7621 gcatcatttt gaccttgctt ggtttcttcg tcaattatta tctgagaaag gttgatatgt
     7681 tagaagccct gaaatctgta gagtaaggta gttattttta gctgattgaa cttctattta
     7741 ctaatattca aaaatcctcc gtttcaaaga gcagggaact ctttgtgaca gaggattttt
     7801 tctatagggc tttagcagct gcaattgcgg cttcgaagtt tggctcagaa ttgatattat
     7861 ccacgtattc aacgtagcga atcgtattgt cagtatcgag gacaaagact gcgcgtgcta
     7921 ataggtgcca ttcgttgatc aagagggcat aatcgcgccc gaaagaatgg tcaaagtagt
     7981 ctgaaagcat aatggcattg tcaaggcctt cagcaccgca ccaacgtttt tgagcaaaag
     8041 gtaggtccat tgaaacagtc aatacgaccg tgttgtccag tccagccaat tcttcattaa
     8101 aacgacgtgt ttgagttgag cagatgcctg tatcgataga aggaacgaca ctcaagactt
     8161 ttttcttgcc atcaaaatca gccagagatt ttttagaaag atctgttgta gtaagagaaa
     8221 aatcaagcgc cttgtcgccg acttgtagtt gtttacctgt aaagctcaca ggatttccga
     8281 gaaaagttac cataggatac tccaatcttt tttcttccat tgtatctgaa acagtcagaa
     8341 ttttccaatg atttgaccgg aaatgtgggc atagaaaaaa cgccagctca catgagaatg
     8401 acgtttttca gaggcttatt ttgccaatcc ttcagcaatc ttgtcaaggt tgtatttcat
     8461 catgctgtag tagctgtcgc cttctttacc ttgttctgcg atagagtcag taaagatttg
     8521 tgcgtagatt gggatgtttg tgtcttgaga aacagttttc attggacggt catccacact
     8581 tgattctaca aagagtgatg gaacttttgt ttggcgaagt ttttcaacca aggtcttgat
     8641 ttgttcagga gttccttctt cttcagtatt gatttcccag atgtaggcac ttgggacacc
     8701 ataggcttta gagaagtatt tgaatgctcc ttcgctggtt acaatgagtt tcttttcagc
     8761 agggatctta ttaaatttat ccttactttc tttatcaagt ttgtctaact tatcagtata
     8821 ttctttgaga tttttttcat agaattcttt attgttaggg tctttggcgc tcaattgttt
     8881 ggcgatattt ttagcaaaaa taataccgtt ttcaaggtta agccaagcgt gtgggtcttc
     8941 ttttcctttt tcattttgac cttcaaggta gataacatca acgccgtcgc tgactgcgaa
     9001 gtagtctttg ttttcagttt tcttggcatt ttctaccaat tttgtaaacc aagcattgcc
     9061 acctgtttca aggttgatac cgttatagaa aatcaaatca gcctcagaag ttttcttaac
     9121 gtcttcagga agtggttcgt attcgtgtgg gtcttgccca atcggaacga tactatgaag
     9181 gtcaattttg tcaccagcaa tatttttagt aatatcagcg atgattgagt ttgtagcaac
     9241 aacttttagt ttttgaccag aagttgtatc tttttttccg ctagcacatg ctacaagaat
     9301 gattgcagaa agaaagagaa cgagtaatgt acctaatttt ttcattagat cctccaattt
     9361 attagggctt tgccccttat tttaacaaat gtttattttt cagtttcaaa tatcgttgtt
     9421 tgggagcgat aaagaagcta atgagaaaga aactagcagc tgtaagcacg atactagaac
     9481 ctgccgcaac attaaaacta tagccaataa agagtcccaa aactgaagca gtagctccga
     9541 aggttgagga aaggaaaatc atgcttttca gactattagc atacagataa gcagttgcag
     9601 ctggggtaat cagcatggct acaatcagga tagttccgac actttgcatg gctgtcacag
     9661 acacgagagt caggagtacc atgagaaggt agtgatagaa attgacaggc attcccatgg
     9721 ctttagccaa gagttcatca aaggaagtta tcaagagttg cttgaagaaa atccaaatta
     9781 acaagaggat ggctgccccc acacccatag taataaacat atccgtatct tggacggcca
     9841 gaatattacc aaaaaggata tggaaaaggt cagttgaact tttagcgaca ccaatcaaga
     9901 tgataccgag ggctaagaaa gaagaaaagg taatgccgat ggcggtatcg cttttgataa
     9961 tcgagtttcc tttgatgtag gtaatgatga tggcagctag caatccaaag acaatggctc
    10021 cgataaagaa gtcaaggccc aagatgaagg agagggctac acctggtaag acagcatgtg
    10081 aaatggcatc tcccatgagt gacatcccgc gtagaataat gaaacatccc acagctccag
    10141 ctacaatccc gacgacaata gctgttatca aggcattttg taggaaatgg aatttttgca
    10201 atccatcgat aaattctgca atcataggtc acctccattg aaaaagagtt gattaccgta
    10261 agcttctttt agattggttt cggtaaaagt ttcttttgtt ggaccaaagg caatcacttc
    10321 tcgattgaca agtaagactt gatcgaagta gtggggaatc ttgctgaggt cgtggtgaac
    10381 gatgagaacc gtcttcccag cttttttcaa atctctcagc gtattcatga tgatttcctc
    10441 actgacagag tcaatcccag caaagggttc atccaagagg atatagtcgg cttcctgcac
    10501 caaacatctg gcaatcaaga cccgctggaa ttgacctcca gacagttgac taatttgacg
    10561 ttcagcgtag tcagctaggc cgacgatttc aagggcctct tgcactttct tccaatgttt
    10621 agcctttaaa cttcgaaaga gaggaataga gggaaatagt cctaacgaga cgcattcctt
    10681 gaccttgatg ggaaagttgt agtcgatatt gattttttgt tcgacatagg caattcggtg
    10741 taaggatttt ttaacttcct tgtcatcgag aaatgcctga ccttgatgtg ggataattcc
    10801 cagcatacct tttaatagtg ttgatttccc agcgccgttt ggaccaatga tgccggtaat
    10861 tgttggtcca tggagcacta gtgaaatatc cttaagtgcc aacgtttctt tgtaggagac
    10921 actgaggttt tcgatacgta tcataaactt gtattcctcc tgtctcttaa tatacattaa
    10981 aaaaaaaatt aagtcaagtt aatttttgaa aaaattaaaa taataactga aaaatagatt
    11041 ctaaagataa ctttcaggat aaatttctaa attataaaac gcatagtatc aagtgtaaaa
    11101 aacttggaat tatgcgtttt atcatggaaa ggttttttat aatagctaaa aaataatagt
    11161 taaatggtta ttaattgcat tccctagtga tttttgttaa gataaatgca aatacaaatg
    11221 aaagcgagaa caagatgaca cgttatcaag atgattttta tgatgctatc aatggagaat
    11281 ggcaacagac agctgaaatc ccagcagata agtctcaaac aggaggtttt gttgatttag
    11341 accaggaaat tgaagacctg atgctggcga caacagacaa gtggttagca ggtgaagaag
    11401 tgcctgagga tgctatcttg gaaaactttg tcaaatacca ccgcctagtt cgtgattttg
    11461 acaagagaga agctgacggt atcacacctg tcttaccact ccttaaagaa ttccaagaat
    11521 tggagacttt tgcggatttt acagctaaac tagcagagtt tgagcttgca ggaaaaccaa
    11581 acttccttcc ttttggtgta tcgccagact ttatggatgc tagaatcaat gttctatggg
    11641 ctagcgctcc aagcacaatc ttgccagata cgacctacta tgcagaagaa catcctcagc
    11701 gcgaagaact cttgactctt tggaaagaaa gcagcgcaaa tctcctcaag gcttatgatt
    11761 tctctgatga agaaattgaa gacttgctag aaaaaagact tgaattggac cgccgagttg
    11821 cggcagtggt gctctctaat gaagaaagtt cagaatatgc taaactctat catccatatt
    11881 cttacgaaga tttcaagaaa ttcgcgcctg ccctaccttt ggatgacttc ttcaaagcag
    11941 ttattgggca attaccagac aaggttattg tagacgagga acgtttctgg caagcagcag
    12001 agcaattcta cagtgaggaa gcctggtctc tccttaaagc aaccttgatt ttgagtgttg
    12061 tcaatctttc aaccagctat ttaacagagg atatccgtgt tttgtctggt gcctacagcc
    12121 gtgccctttc tggagttcca gaggcaaaag ataaggtcaa agcagcttat catctagcac
    12181 aggaaccttt caagcaagcc ctggggcttt ggtacgcccg tgagaagttc tctccagaag
    12241 ccaaggcgga tgtggagaaa aaagtggcaa ccatgattga tgtctataag gagcgtctgc
    12301 ttaagaatga ctggctcact ccagaaacct gtaaacaggc tatcgtgaag ctcaatgtga
    12361 tcaaacctta tattggctat ccagaagaat tgcctgcacg ttacaaggat aaggtagtga
    12421 atgaaactgc cagtcttttt gagaatgctc tagcctttgc gcgtgtggaa atcaagcaca
    12481 gttggagtaa gtggaaccag cctgtagact ataaggaatg gggcatgcct gctcatatgg
    12541 tcaatgccta ctacaatcct cagaagaacc tgattgtctt tccagcggcc attttacagg
    12601 cgcctttcta tgacttgcat cagtcatctt ctgctaacta cggtggtatt ggggcagtga
    12661 ttgcccatga aatttcccac gcctttgata ctaacggggc ttcctttgac gaaaatggta
    12721 gcctcaagga ttggtggaca gagagcgact atgctgcctt caaggagaaa acacaaaaag
    12781 tcattgacca atttgatgga caggattctt atggagcaac cattaacggt aaattgactg
    12841 tatcagaaaa cgtggctgac ttgggaggaa tcgcagcagc gcttgaagca gctaagagag
    12901 aagcagactt ctcagcagaa gagttcttct acaacttcgg tcgcatctgg cgcatgaaag
    12961 gtcgaccaga atttatgaaa cttttggcta gcgtcgatgt gcacgcacca gccaaactcc
    13021 gtgtcaatgt gcaagtacca aacttcgacg atttctttac aacctatgat gtcaaagaag
    13081 gagacggaat gtggcgttca ccagaggagc gcgtgattat ttggtaatac aaaaaatcta
    13141 gtcatcagaa aaaaggcatc caatcacgtg tgaaaacctt gataggatgc cttttgtaat
    13201 agaaagattt gctggatagt ttacttaaat ttcgattgtc atcatcttgc tagaaaaagg
    13261 gattgaaggc cttttcgtga gcgatagtag tagctggacc atgtcctgga tagacatcgt
    13321 agtttggtag ggtgaagagt tgggtctgga tactatgaag gagttgctcc atgctaccag
    13381 tcggaaggtc ggtccgtccg atagtttcgc ggaatagagc atctcccgtc aagactaggt
    13441 gagcatcagg aaagactagg gaaacaccac cgatagagtg ccctggggtc ggtagaacct
    13501 taaaacgaaa ttcctctagt tggtattctt cgtgaaagac aaaggtgtgt tctgcaggtt
    13561 ttgtgaccac atctgccata tcatcgtggc gagggagacc ggagagatta tcgacaggag
    13621 tgtagagcca gctggcttcg ctctctgcga tatagacagg aggattgcca aacgtctcgc
    13681 gaaccaagtc cagactcatg atatggtcat aatgggcgtg ggtcaagaga atagcacaga
    13741 tcggtttgtt gatcttctcg attgtctgac gaatggcttc ccaatgacta ccaggatcga
    13801 cgacgatgag gtgcttttcg ccttctagat aataggtatt ttcataggca acaggattca
    13861 cggttttatg gattttcata ctagctccaa tctcaaagaa tgtactaata ctcttcgaaa
    13921 atctcttcaa accgcgtcaa ctttatctgc aacctcaaag cagtgctttg aacagcctgc
    13981 ggctagcttt ctagtttgct ctttgatttt cattgagtat aaattaagta tagcacagtt
    14041 agggagaata ggtaaggatt taaaatgaac ttaaaaacca gcatgactag atgaagacag
    14101 gctggttatc aatttatcaa tattggaaag gtgtcaattg cccttcatag gttgcataaa
    14161 ctccgtcatt agcttgtttg atagacgtga tgtttagagt gctaccgtag ttggcttctc
    14221 atttgtcgct atattcacta taagttatcc tactgggcag gttctggtcg ttagcatagt
    14281 attgaacgag ttttttatag ctttgctggc tgaataggaa caggcagcaa actcctaaca
    14341 ttaggagagc aaagatagaa atagcagttt tttcataggt attctcctta taaactaaag
    14401 gatagaagaa agtatcttga ggatttttat actcttcaaa aatctcttca aaccgcatca
    14461 acgtcgcctt gccgtatata tgtgactgac tttgtcagtc ttatctacaa cctcaaagca
    14521 gtgctttgaa cagcctgcgg ctagtttcct agtttgctct tggattttca ttgagtatta
    14581 attccaaaat ccagtcaagg taccagtgta tgtgatacga gttccaccgt ttatctttcg
    14641 tatcttcaat ggaattgggg aagtcagaaa gtctttgggt tacaatatgg tttccgttct
    14701 tctatctctc cttctatcac ctaagtttaa aatctaactt cgtagtatat tatggaccaa
    14761 taattcagaa ttatcaagca attttgaatt atttttttct tattctgttc caatctagtt
    14821 ttcatattct taaaaaagtg ataaaatggt aggaagaatt ggagagtaga gatgccgaaa
    14881 gaagtgaatt taacaggcga agaagttgtc gctttaacca aagaatattt aacggaagag
    14941 gatgttcatt ttgtccataa ggccttggtc tatgctgttg aatgccacag tggtcaatat
    15001 cgcaaatcag gcgagcctta tatcattcac cctatccaag tggcaggtat tttagctaag
    15061 ctaaagctgg atgctgtaac agtagcttgt ggattcttgc atgatgtggt ggaagataca
    15121 gatgcgacct tggacgattt ggaaagagag tttggtcctg atgtgcgggt gattgttgac
    15181 ggagttacca agcttggcaa ggtcgagtac aaatcaatcg aggagcaatt agcggaaaat
    15241 catcgcaaga tgctcatggc catgtctgag gacatccgcg ttattttggt caaactgtct
    15301 gaccgcttgc acaatatgcg gaccctgaaa catcttcgaa aagacaagca ggagcgtatt
    15361 tccaaagaaa ccatggaaat ctatgcccca cttgcccatc gtttggggat ttccagtgtc
    15421 aaatgggaat tagaagactt gtctttccgt tatctcaatc caacggagtt ttacaagatt
    15481 acccatatga tgaaggaaaa gcgcagggag cgtgaggcct tggtggatga ggtagtcaca
    15541 aaattagagg agtatacgac agaacgtcac ttgaaaggga agatttatgg tcgtcccaag
    15601 catatttact caattttccg caaaatgcag gacaagagaa aacggtttga ggaaatctat
    15661 gatctgattg ctattcgttg tattttagat acccaaagtg atgtttatgc catgcttggt
    15721 tacgtgcatg aattttggaa accgatgcca ggtcgcttca aagactatat cgccaaccgc
    15781 aaggccaatg gttatcagtc tatccatacg actgtttatg gaccaaaagg gccgattgaa
    15841 ttccagattc gaaccaagga aatgcacgag gtggctgagt acggggttgc ggctcactgg
    15901 gcttataaga aaggtataaa ggggcaagtt aacagcaagg aatcagctat tggaatgaac
    15961 tggatcaagg agatgatgga gctccaagac caggctgatg atgctaagga atttgtggac
    16021 tctgttaagg aaaactattt ggctgaggag atttacgttt ttaccccaga tggagctgtc
    16081 cgttcccttc ccaaagattc aggaccgatt gattttgcct acgaaatcca taccaaggtc
    16141 ggtgaaaaag caactggtgc caaggtcaat ggccgcatgg ttccactgac aaccaagtta
    16201 aagacagggg atcaggttga aattatcgcc aacccgaact cctttggacc tagccgtgac
    16261 tggctcaata tggtcaagac tagcaaggcg cgcaataaga ttcgccagtt ctttaaaaac
    16321 caagataagg aattgtctgt caacaagggt cgtgagatgc tgatggctca gttccaagaa
    16381 aatggctatg tggcaaataa atttatggac aagcgccaca tggatcaagt tctgcaaaag
    16441 accagttaca agacagaaga ctccctcttt gcggccattg gttttgggga aatcggtgcg
    16501 attaccgtct ttaaccgtct gactgaaaag gaacgccgtg aggaagagcg tgccaaggcc
    16561 aaggctgagg cagaggagct tgtcaaaggt ggcgaggtca aggttgaaaa taaagaaact
    16621 ctcaaggtca agcatgaggg gggagtggtt attgaaggtg cttctggtct cctagtgcgg
    16681 attgctaagt gttgtaaccc cgtgcctggt gacgatattg ttggctacat taccaagggt
    16741 cgtggtgtgg ctattcaccg tgtggactgt atgaacctgc gtgcccaaga aaactacgag
    16801 caacgtctcc ttgatgtgga atgggaagac cagtactcta gctcaaataa ggagtatatg
    16861 gcccatatcg atatctacgg tctcaaccgt acaggactgt tgaacgatgt actgcaagtt
    16921 ctttcaaata caaccaagaa tatttcaacg gtcaatgccc aaccaaccaa ggatatgaag
    16981 tttgctaata tccatgtgtc cttcggtatt gccaacctct ctacactgac tacggttgtc
    17041 gataaaatta agagtgtgcc agaagtttac tctgtcaaac ggaccaacgg ctagttgtcc
    17101 tagctcttac tagaaaggct attatgaaaa tcattatcca acgggttaaa aaagcccaag
    17161 tgagtataga aggccagatt cagggaaaaa tcaatcaggg acttttattg ctagttggtg
    17221 ttggaccaga ggaccaagag gaagatttgg actatgctgt gagaaaactg gtcaatatgc
    17281 ggattttttc agacgcagaa ggcaagatga acctgtctgt caaagatatt gaaggagaaa
    17341 tcctctctat ttctcagttt accctctttg cggatactaa gaaaggcaat cgtccagcct
    17401 ttacaggggc agctaaacct gatatggcat cagacttcta tgatgctttc aatcaaaaat
    17461 tagcgcaaga agtgcccgtt cagacaggta tctttggagc agatatgcag gttgagctgg
    17521 ttaataacgg acctgttacc attatcctag atactaaaaa gagataagaa agaccaagcc
    17581 cagtcggctt ggtctttctc atcgatcata aaatactcca aaaagaaatc ggttcttgat
    17641 atgcttgggg gaagtctctt ttcaggcttt ggcagatgcg ataggaaggg atgagatgtc
    17701 ctaggatgag gagagttccc tgaaggaaaa gtggaatatc acttaaagac accaaggaga
    17761 gaatcatcag gctatcccat aggagaattt gtaaagcaaa acgccagaat ctcggcctaa
    17821 tctgggaata gagttgacta aagtggtcac aaagttggtt tgaaagatag gtcaatagca
    17881 caggatgaaa gaaaatgagc caaccactat aaatcaaaat ccagtcccaa gtaagccccc
    17941 cttttaaatg tcaaaaatgc cagcatgatt ccatcaatga caaggagttg aatggttttg
    18001 atgaagatga tttttttcat gctaaaacct ccttttcctt agagacactc ccataaagag
    18061 atgtgtttgt cgtaaaagtc tggatagttt tctcttaggt agtcagctgt catataataa
    18121 aaagtagaat ggcaagcagt gataattgac ataagagatg aaaaacgctg agaactaatg
    18181 aaggctaaga gaacaaaaaa tagaaaatca atggtgagaa cccctaaata gtagaagcga
    18241 atctttttat tgatttgagg ataaatctca gcgaattgat gtttgagtcg gacgatcaag
    18301 agaaatagca ggagtccttg agcaaggaag aaaattaaac cagagagcaa gagccactca
    18361 aaagatgtct cgagtctagt gataaaaaat gcaaatagta gcaaatcaat aactgcaatt
    18421 gctataaaat ggattctata gagttttttc atgacaagac cttcctcttt tatctaactt
    18481 cattctactc caaaagaatg ggagttacaa ctaaaatgat aaaaatagca gaagggagat
    18541 tctcttaagt tggctagtat tctttatttg agtttccttc tatgtatcta acttcttcat
    18601 cattccagac aaataaagct ccgattgcat tgaggatata aaagatgtat ttaccgatat
    18661 tggcgaagtt tccttgaata ccagcttttg tcagctgaac gaaattgtaa atcaaccaaa
    18721 agccccactg agttgttagt ttcaatgcat tcaaagcatt ggcaatgagg gacagtgcaa
    18781 aggcaatagt tgttacgtag gcaaggagat ccatcttgcc ctcatatccg atatagttgg
    18841 tcacaaaggc aaagaggaag gcgatgatgg aaatgatgat ggccgccaat tttacctgtt
    18901 tttggctcat ttggttgggt ctgccttctt gcgaagcttc ccacttcttt atagcaaagg
    18961 tataaatgag gaaggtgacg ggataggtaa tgatggccgc cttatttcca aggatataat
    19021 caatagcacc gaacaaaagg gtattaacaa taccaaagta atttccccat ttgcttaatt
    19081 tccccgtgaa acgagtggac aacatggaaa tcccaacgtt ggttacggaa atcaatccaa
    19141 agggtacaag agctgtccat gatccccagt ctacaaattt atcgaggcgt gagttgagat
    19201 aaccagatgc aatcgcaatc ccaacgacca aagcaacccc gaagaggtca aatcatttag
    19261 atgtagcaaa aatttttagt gattttttca taggttaaac tacctttctt tttttcaaat
    19321 attctcccat tttttttcaa atattctacc accaaatgaa agtaaaataa aatgatagaa
    19381 ataaaaccct gaaaataaaa ctttcagggt tggtagggga cttgagaaat tagttgattt
    19441 tctcgacata gagttgtttt gcaatgtcca tattcacttg taaatcctcg tcgttactga
    19501 ggatagtgaa ggtattgctg aagccatcaa actgcttgac ttggagctgg tcaccgatgt
    19561 gaagtgagtg cttgtccaga taatggagaa tgtcaaaatt atcgtgcacc cgagtcaggc
    19621 ggtaggcgcc agcttccttg atatcagcta gtgggaggtt attgatttca acgaggagtt
    19681 ctcccttggc aggaatagtt cctccgtggg ggcaggtttt agggaaacct agcagtttat
    19741 ctagtctttc cacgaacagg tcagagacag tgtgttccaa gacctcagct tcctcgtgaa
    19801 tctggtcact tgtatagtct aaatgatgaa ctagaaaaac ttcaatcaag cggtgcttac
    19861 gatagagctc agagactagt ttgagaccga ggtcagtcag tagatagcca cattccttgt
    19921 cctttaggat gaggttttca cttttcattc gtttgatcat ttcagttacg gcagggggag
    19981 agacttgcat gcgagccgca atttccttgt tggtaatctt atgcaggtct atgccaattt
    20041 cataaataca ttttagatag tcttctttgt ttggggtcat tcgtttcctc ttgtctaata
    20101 tctttatcta gtatatcaaa aaaagctaga tttctctagc tgtgactttt tatgttatac
    20161 ttattgcaag agaaaaaacg aggagatgga tatgacgaaa atagctcttc tttcagatat
    20221 tcatggaaat accaccgcct tggaggctgt tttggcagat gctcggcaga taggagtgga
    20281 tgaatactgg cttttgggag atattctcat gccagggaca ggacgtagaa ggattttgga
    20341 cttgttgaat caactaccga ttacggctag agttttggga aactgggaag acagtctttg
    20401 gcatggtgtc cgtaaggaat tggacagtac tcgccccagt caacgctatc tcttgcgcca
    20461 gtgccagtat gttttagagg aaatttccct agaagaaatt gaagtgctcc acaatcaacc
    20521 tcttcaaatt catcgtcagt ttggggattt gacggtggga attagccatc atctgcctga
    20581 taagaactgg gggcgagagt tgattcatac tggcaaacaa gaggagtttg accgcttggt
    20641 gactcatcct ccctgtgata ttgctgttta tggacatatt caccagcagt tgcttcgtta
    20701 cgggactggt gggcaattga ttgtcaatcc gggttcgatt ggccaacctt tctttttgga
    20761 cgctcagcta cggaaggact tgcgggccca gtatatgatt ttggagtttg atgacaaagg
    20821 cctggtagat atggacttcc gacgggtaga ctacgatgtg gcagcggaat tgcagctggc
    20881 taaagacctg agacttccct attttgaggt ttactatgaa agtctggtca atgggatcca
    20941 ccatactcat catcaggaat ttttgagaga attggctcag aaagagggct gcgatcggga
    21001 gttagacgac tggttgaaaa gtggtaacga ttgacattac aactaaaaag ggtataataa
    21061 tagaaaaaga agagtagagg cagggtagcc tcgtaaaaag gagaagagga tgcaaattcc
    21121 aagtagattt accattgcga ctcatatgct gataatcatt gccctcgagg ggaaggaaag
    21181 caaggtgacc agtgattttc tggctgctag tgtcggggtc aatcctgtca ttatcagaaa
    21241 gatcttgtcc cagttgaaga aggcagagct gatttcagta gcgcgtggaa cgggcggaac
    21301 agagattgtc aaggacctta aggatattag tcttttagat gtttatcagg cggtcgaatg
    21361 tcttggtaag acaggtcaac tcttcagttt tcatgacaat ccgaatccaa attgccctgt
    21421 aggagctcat attcatgatg ttttggatca aaaattggag agaattcagt tgactatgga
    21481 ggcagaactt ggtcaaacca gtctagaaaa agtcgtggcc gatgcagaga gtcagatgaa
    21541 ggattaagag ggataaatgc cctctttttt ctttggataa ttatgataaa atgtagctat
    21601 taaaggagta agaaatgtat ctcgttatag gaattgtatt agcctttata gtgtcatttt
    21661 ggaaggataa tagaagtttg tggaatccag tattattttt attatccctc atttcaagtt
    21721 atttttatct atcctacctt ttttataaaa atggatacga gaatgttcag ttagcttttt
    21781 atgtatttgc ctttgtctta cttccttttt tgctttttct aagtggcatc tttttaatct
    21841 ataatggggt cattttgttg aagcgagagg gacgttccaa gccccattat ctctcaatgc
    21901 tctttgattt ttattgacta ttagattcta tttaaaaaga tttagaatgc acatgaaagt
    21961 atgtattcta ggtcttttgt tttgtataca tttaattttc aagagtatta tctatttttc
    22021 catgcctggt aacgagtatc aatcaataac tgggtaaggc gacccaaggt ttctctttct
    22081 tctggagtga gggattgagc ttggacaaag agatgatgaa tgtattcaag cgcctttaag
    22141 gaagccaagt cattgataga gctaatacca gcctcaagaa tagtgccaaa gaagaggtcg
    22201 aagtagagct gaagttcttc gtcagggact gtggccaccc attctttaaa ggttgtgtct
    22261 acttgctggc tatcactgtt ggtcttatcc agttggacga agtgcttgtc ctcaatctgc
    22321 caactaaagg tatcgtgctg ggcgatgcca cccagggcag tactctgaac gatgatttgg
    22381 tgagcaggaa tttccagcat cataccgata atggaacctt gtggaatgaa tatcttgctt
    22441 ctatccatta tcctttgata acccgcagtc tgtgtcaatt cttgatggag accaggtgca
    22501 tcaaatgtat aaactgctgt gatctgattt tgcaaacttt gctcaatttg gctagcagca
    22561 tagatagcga gatttcctcc cttggaatgc ccagccagaa taactttttg cttaggatga
    22621 tgggcaaaaa agttctttaa atagcgaagg gcgtgctttt gagcaggaat ttccttcata
    22681 taggtcaggt ggaaatcttc cttccagcca atgatactgt catctgtccc acgaaagaca
    22741 atcagatagg tatcgaggct gacacgataa gtcatagccg caaattgctt ttgcagttca
    22801 gggtcgatgt cgttgataaa atgggagagt ttgcaatttt tgaagcgctt gtgttgagcc
    22861 aatttatcta ataattgaag gcgatttttg ctagtaagca tggtgggctc tcttggaacc
    22921 tgaggtgcta gatctaaaag acgttgagga agtgtggaga ccagattatc aaaggagagg
    22981 taggtgattt ctattaaggt tagaatgtct aactcattca agggaaggtc gtaataagaa
    23041 tcatatgcga catctttcag atagtcaaaa atattggcca taagagctcc tttcttttta
    23101 tttatcttag caaatttccc tcaaattagc tagtagcatt gcctgtttgt actggctaaa
    23161 aacaggctat ttcaaattca gtttcagacc atctggcatg gaaaaatctg ttataataat
    23221 ggaaaaggag aagcgcatgc acaagatttt attagtggaa gatgatcagg tcattcgtca
    23281 acaggttggg aaaatgctct ctgaatgggg atttgaagtg gtcctggtag aagactttat
    23341 ggaagttttg agtctatttg ttcagtcgga acctcatctg gtcctcatgg atattggttt
    23401 gcccttgttt aatggttatc actggtgtca ggaaatccgc aagatttcca aggtacctat
    23461 catgtttctt tcttcgagag accaggctat ggatattgtc atggcaatca atatgggggc
    23521 ggatgacttt gtgaccaagc cttttgacca gcaggttctt ttagctaagg ttcagggctt
    23581 gttgcgtcgt tcctatgagt ttgggcgtga tgagagtttg ctggaatatg ctggtgttat
    23641 cctcaatacc aaatccatgg atttacatta tcaagggcaa gtcttgaatt tgaccaagaa
    23701 cgaattccag attttacgcg tgttatttga gcatgcaggc aacatcgtag cacgtgacga
    23761 cctgatgcgg gaactttgga acagtgactt tttcattgat gataataccc tctctgtcaa
    23821 tgtggctcgt ttgcgtaaaa agttggagga gcagggattg gtaggattta tcgagaccaa
    23881 gaaaggaata gggtacggat tgaagcatgc ttgattggaa acaatttttt ctagcctatc
    23941 tacgctcccg tagtcgtctt tttatctatc tgctttcttt ggcatttctt gtcttactct
    24001 ttcagttttt atttgccagt ctaggaattt acttcctcta ctttttcttc ttgtgttgct
    24061 ttgtaaccat cttatttttc acttgggaca tattggtgga aacgcaggtc tatcgccagg
    24121 aacttctcta tggagagagg gaagccaagt ctcctttgga aatagcttta gcagaaaaat
    24181 tagaagcgcg tgagatggaa ctctatcagc agaggtcaaa agcagaaaga aaactgacgg
    24241 atttgctgga ttactatacc ttgtgggtcc atcagataaa gacccccatt gcagccagtc
    24301 aactcttagt tgcagaagtg gtcgaccgcc aactgaagca gcagctagaa caggaaattt
    24361 tcaaaatcga ctcctatacc aacctagttt tacagtacct gcgtttagaa agtttccatg
    24421 atgatttgct cttaaagcag gttcaaattg aggacttggt caaggaaata attcgtaaat
    24481 atgctctttt ctttattcaa aaaggcttaa atgtcaatct acatgacctt gataaagaaa
    24541 tcgtgacgga taaaaagtgg ctgctagtgg ttattgagca aatcatctca aacagtctca
    24601 agtacaccaa ggaaggtggt ctggagattt atatggatga ccaagagctt tgtatcaaag
    24661 atacgggaat cgggataaaa aacagtgatg tcctccgagt atttgaacgt ggcttttcag
    24721 gatacaatgg ccgtttgacc cagcagtcct ctggacttgg cctttatcta tctaagaaaa
    24781 tttctgaaga actggggcac cagattcgta tcgagtctga ggtcggaaaa ggaacgacag
    24841 tgcggattca gtttgctcaa gtgaacttag tccttgagta aaaatagatg agaaaaagcc
    24901 tccagattgg aggcttttat gctagactct tatttctcaa cgcgtgattt gttggcgata
    24961 tcagctagga tagcttgaac aaaattatca actgagacag tttgtgtttc tttttggccg
    25021 tagcgacgaa cgttgactgt ttcgtcttcc atttctttgt ctccaacaat taattggtaa
    25081 ggaatcttgc tggtttgtga agcacggatc ttgaactgca ttttttcatt gcgctcatct
    25141 acgtctgcac ggacaccgcg gtcacggagt ttcttggcca cttcccaagc gtagtccacg
    25201 tgtttttcgt tagatactgg gatgagggtt acttggtgtg gtgccagcca tgttgggaag
    25261 gcccccttgt agttctcaat caagatagct gtgaagcgtt ccatagttga gataacccca
    25321 cggtggatca tgactggacg gtgatcttcg ccatcagctc cgatgtattt gaggtcgaag
    25381 cgttctggca acaagaaatc aagttggata gtagaaaggg tttcttcttt tccaagggca
    25441 gttttaatct ggatatccaa ttttggtccg tagaaggctg cttcaccttc ggcttcaaag
    25501 tagtccacgc ccatttcatc aagagctgca cgaagcatgg tttgggcatt ttcccacatc
    25561 tcatcgttat caaagtactt atgagtatct tgagggtcac gaagagagag gcggaagcgg
    25621 tagtcagtca agttgaagtc ttcataaaca tcgataatca actgaagggc acgttggaat
    25681 tcttcttgga tttgttctgg agtaacgaat aggtgaccgt cgttgagtga catttcacgt
    25741 acacgttgaa ggccagtgag ggcaccagat ttttcgtaac ggtgcatcat accgatttca
    25801 gcgatacgga ttggcaattc acggtaagag tgaacatggt gtttgaaaac ttggatgtgg
    25861 tgcggacagt tcattggacg aaggacaaat tcttccccgt cacccatgtc catggttggg
    25921 aacatgtctt cttggtaatg atcccagtga ccagaagtct tgtaaagctc aacagaagca
    25981 agtggtggag tgtagacgtg ttggtagcca gaagccaact ctttgtttac gatgtagcgt
    26041 tccaattcac gacggatagt cgcaccattt ggtaaccaga atggcaaacc ttgtcccact
    26101 tcttgtgaaa tcataaagag gtcaagctct ttaccaagtt tacggtggtc acgttcctta
    26161 gcttcttcac gcatttgaag gtagtttttc aagtctttct tgtcaaacca agctgtacca
    26221 tagatacgtt gcatcatagc gttgtcgctg tttccacgcc agtacgcacc agctacatgg
    26281 agaaggtgga agatttggat acgacctgtt gatggaacat gaggtccacg gcagaggtct
    26341 acatattcac cctgacgata gatagtcaaa ccgccttcgt cttctgagtg ttcttcaatc
    26401 aattccaact tgtaagggtc atttttgaag atttcacgtg cctcgtcttt agtcacttct
    26461 tcacgaatag atgggaagtt ttctttgacg attttttgca tttcttcttc gatacgagga
    26521 aggtcttcgt tagagatttg accagctgtg ttgtcagtat cgtagtagaa accatcttcg
    26581 atggctggac caactcccaa gtgaatgtct gggaaaagac gacgagctgc ttgggcgaac
    26641 aagtgagctg ctgagtgacg caagattgga agggcatctt cgtgatcagg tgtcacaatt
    26701 tcgatgcttc catcttcagt gatagcgcga gtagtgtcga tgagtttgcc gttgaattta
    26761 ccagccaagg cttttttagc tagggaattg ctgatagatt gggcaatttc aaaagttgtt
    26821 acgccagatt cgaattcacg aacagcgcca tctgggaaag taatgttaat catgatgttc
    26881 tcctttttta ttatttcata gtttctaagc attgattttt tatcagcaga ctacttccga
    26941 gtcctaacgt tcaattgctt ttctttatca gagaggaagt tttccatttc cgtcagaatg
    27001 tctatatcca aacgttgaga aagttctaat agccaccaga tattttctga aagtttttgt
    27061 tccagtgtgt agggtgtttc atcatagtag cgtccttgct ttgtcatcac cagtcattgg
    27121 aaatttccaa tatcattaga taaagccaag aggtcttctt ctaccgtcca cttgaaatca
    27181 tgatgcttaa cttccagttc gtgataagct tgtcggattg cccaactgcg ctccactaat
    27241 tcttgcaact ccataattag tatcctaata aaaaaatgcg acatcctcga aaggacgtcg
    27301 caacgtggtt ccaccttcat ttatgtacct caaaagagag ggacacctct gatcggctct
    27361 aacgtggcca ccgttttatg ttttcataaa aaactcaaga gtagtatcag tttagacttc
    27421 ctatgcgttt ccagcaacca cgcactctct agtagaaagg gactaagtga cttgtctcta
    27481 tggattatta tagcatgatt gtgagatttt tcaaggattt tgtgaaagtt ttttgttttt
    27541 cattttttgt agaatatgct tgatgctaat accagaatcc atgccgacca gagcaactgt
    27601 ttcatagatt agcaagtaaa ttagtataaa ctcaccaaag gttatgatag taaagtaaaa
    27661 gagcagtccg ttaccaacta accatcaaag tgagaaacgg aaacggtagc tatagagtaa
    27721 cgatataatc aagattacca gaggtgtaaa gaagagaaga ttgtttatat agagttcctt
    27781 gagtgtaagg gggtcagaaa caactagtaa gaacaactca taaagtggtc aataaaagaa
    27841 taatatgacc agatagtagg ggagatggga atagaatcta cgcatgataa tcacctcgtt
    27901 ttaaaaaaac agacaactta gatctcttgc tatgattatt atagcatgtt taaaacaaga
    27961 aagtaaattt gttgacaaag aagatttttc ttttcactag aatcatagtt agttttcttg
    28021 gtagaaatat tttgataata attaagcaag actattgaca ttgattatta agagtgtcac
    28081 aattattgta actaaaataa ttacaacaag agaggtataa aaaatgaaac tagcagttat
    28141 tgcagcaaat ggacaagcgg ggaaagcaat tgttgaagaa gcagtcaaac gaggacatga
    28201 agtaacggct attgttcgtt ctgaaaacaa aagtcaagct gagtctatta ttaaaaaaga
    28261 tttatttgag ttgacaaaag atgatcttac tggatttgat gctgttattt cagcgtttgg
    28321 tgcttataca ccagatacgc taccgctcca cagcaaatca atcgaactat ttaatcagct
    28381 tcttgctgga acacagacac gttttctagt tgtaggggga gcaggaagtc tttatataga
    28441 tgaaacaaaa acgacacgac ttttagatac gtctgatttt cctgaagaat ttaagtcact
    28501 agcaaaagat caagcggatg aattggatct tcttcgtaca aaaaataatc tcaactggac
    28561 ttttgtcagt cctgctgtag attttattcc cgatggtgaa aaaacaggaa actacattct
    28621 agcaggagaa atttttacta ctaatgaaaa aggaataagc cagattagtt atgcagatta
    28681 tgctattgga ttggtagatg aacttgaaaa aggtcatcat ataaaagaac atatctcttt
    28741 acttgaaaaa taataactat gagagtatta atgtttgaca gaaaatttaa atcttggtaa
    28801 aatagggatt gtcgtaaaga caaataactt cttcttggtt acaggcatgc caacctgtca
    28861 ctcggatgaa gccaaataaa aaggagaaac atcatggcaa tctcaaaaga gaaaaaaaat
    28921 gaaatcattg cacaatatgc acgtcacgaa ggtgatacag gttcagtaga ggttcaagtt
    28981 gctgtcctta cttgggaaat caaccacctt aacgaacaca tcaaacaaca caaaaaagac
    29041 cacgctactt accgtggatt gatgaaaaaa atcggtcgcc gtcgtaactt gcttgcatac
    29101 ttgcgtaaaa acgacgttaa ccgttaccgt gagttgatca actctctagg acttcgtcgc
    29161 taattcaaga tacaaatgct gtcaaaagca caaagcaaaa ataggaaaat tgacgaagaa
    29221 acttcagttt ctaggagatt ttatcttttt tgccaagtgc ttaggccgtg ttcaattgag
    29281 catatcttga taatgaagct actctaaatt gggtagcttt tttgcgttgt caccttacct
    29341 cgctatactc aagtataatc tttggttacg gttcctagca ctgtaaggta aaataaacca
    29401 gcttttctcc cttcggggag attttttttg tttcactgaa agtttcgtac gatcttcgcc
    29461 tcgtcgccta gtctataaac gatttatcta gcaagaatca tgatgctaag ggcgtcaaaa
    29521 atccgtatga aaatagggaa atgacacagt gttcgatgag cacaaggagt ttcatctttt
    29581 tcactaggat tttagcccgg gctcaaatca gctctctgac ttcagagggc ttttttattg
    29641 aggttttatc ggtaacaatt ttggagacta caaaaacctc aaacggtatc agctaattac
    29701 accataaagg tgcgcagtta ctcggctttt caagccgagt agctgtatgc aagcccccta
    29761 gaagagccca ctctttacaa agtaaagtat agtatgttat actttacatg gaagtagtca
    29821 ctgaattcca gttagaaatt actttgtaac tacgttttga ggaggagtaa aatgctttcc
    29881 tacgttcgac attacccact agcgatagct aaattaatgt gtctgtgctc tcctaaaatc
    29941 tgctgattta ttactgacta atacaggagt tttttttatg ggacagacaa tcatatctgc
    30001 tattggtgtt tatatttcca ccagtatcga ttatttaatt attttaatta ttttatttgc
    30061 acagctatca cagaataaac agaaatggca tatttatgcg gggcaatatc taggcacagg
    30121 cttacttgta ggggcgagtt tagttgctgc ttatgtcgtt aatttcgtgc ctgaagaatg
    30181 gatggttgga ttgcttggtt taatccctat ctatttaggg attcgctttg caattgttgg
    30241 agaagatgcg gaagaagaag aggaagaaat tattgaaaga ttagaacaaa gcaaggcaaa
    30301 tcaactgttt tggacagtta cattgctgac aattgcgtct ggcggagata atttaggtat
    30361 ctatatacct tattttgctt cgttagattg gtcacagacc ctcgtggcct tgcttgtgtt
    30421 tgtaatcggc ataattatct tttgcgagat tagtcgggtg ttatcctcta ttccgttaat
    30481 attcgagaca attgaaaaat acgagcgaat cattgtgccc ttagtattca ttctacttgg
    30541 actatacatc atgtatgaaa atggcacgat agagactttt ctgatcgtgt agattttttt
    30601 gtttcactag gattttagcc cgagctcaaa tcagctctct gattttcaga gggctttttc
    30661 attgagtata aatggacaat cttaaagtta ctctattgta gagtggcttt tgatttgatt
    30721 aggagattct tataaatata gtaaaatgaa ataagaatag gacaaatcga tcaggacagt
    30781 caaatcgatt tctaaaaatg ttttagaagt agaggtgtac tattctagtt ccaatctact
    30841 atataaatga aaaccttagc tgtttggcca aggttcattt cttctatgca agttcttctc
    30901 ttttcttatc tgggttccag atgaagcttg cgataaagct aaagatgatg gttaggatag
    30961 cgaggataat agcaaggatg agggcaggga tgcggataaa ccaccagagt ggatttggtt
    31021 ttttatcatt gtgccattgt ttcgtttctt cgtccagacg ttggaattct gtttgaatac
    31081 gattggcgac tgtttcaatg ccttcatcat tcattttctt gatatctgag atatcgattg
    31141 gatttccaaa gttcatatcg acacgttcac ggctaatcaa gcccttcaaa gtcatgggac
    31201 cggtgtaggt aaccggcatg atacggacct tggccatttt ggcaatcagt gctgcgcccc
    31261 ccttgacatc gtttgagtgg cggctaccac ttggaaacat gatgagagag cggtcacttt
    31321 ttttgagaac gttgatagga tatttgatgg ctgaggcgct gggattttca cggtcgatgg
    31381 gaaaggcgcc acacatacga atccaccaac caaagatacg gttggtaaag agttcttttt
    31441 ttgccataaa gatgaactgt tttggcttgg tcgcaaaggc catataaaca ggatcccacc
    31501 aggtacggtg aggcgcaact aaaatataat tttcatcttg attaggaatt ttatcagtat
    31561 tatgatagtg agcattgcca ttgatggacc ataagagcaa tacaactaat ccacgcaaat
    31621 aagtataaaa catgcgatct ccttcgattg ttttcttgtt attattatac cttatcaaag
    31681 gagggctggc aaacttttcc cttgactaga tacatattta ggatgaaatt agaattctgt
    31741 taaaaaaaat gatataatag aatttatgga taaaaataag attatgggat taacccaaag
    31801 agaagtcaag gaaagacagg ctgagggttt ggtcaatgac tttaccgcat cagccagtac
    31861 cagcacttgg caaatcgtta aacgaaatgt ctttaccctt tttaacgctt tgaacttagc
    31921 cattgctttg gctcttgcct ttgtgcaggc ttggagcaat ctggtcttct ttgctgttat
    31981 ctgctttaac gctttttctg ggattgtgac cgagctacga gccaaacaca tggtggacaa
    32041 gctcaatctc atgaccaagg aaaaggtcaa aaccatccgt gatggtcagg aagttgctct
    32101 taatcctgaa gaattagtgc taggagatgt cattcgtttg tctgcaggag agcagattcc
    32161 tagtgatgcc ttggttttgg aaggctttgc ggaagtcaat gaagccatgt taacgggaga
    32221 aagtgatttg gtgcaaaagg aagttgacgg cttacttttg tcaggaagtt tcctagccag
    32281 tgggtcagtt ttatctcaag ttcaccatgt cggtgcagac aactatgctg ccaaactcat
    32341 gcttgaggct aagaccgtta aacccatcaa ctcccgtatc atgaaatcgc tggacaagtt
    32401 ggctggtttt actgggaaga ttatcattcc ctttggtctg gctctcttgc tggaagcctt
    32461 gcttttaaaa ggcctgcctc tcaagtcatc cgttgtaaac tcgtcgacag ctcttttggg
    32521 aatgttgcct aagggaattg cccttttgac cattacttcg ctcttgactg cagtgattaa
    32581 gttgggcttg aaaaaggtct tggtgcagga gatgtactct gttgagacct tggcgcgcgt
    32641 ggatatgctc tgtctggaca agacgggcac catcacccaa ggaaagatgc aggtggaggc
    32701 tgttcttcca ctgacggaaa cttacggtga agaggctatt gccagcatct tgactagcta
    32761 catggcccat agtgaggata agaatccaac tgcccaagcc attcgccagc gttttgtggg
    32821 agatgttgct tatcctatga tttccaatct tcccttctcc agcgaccgca agtggggggc
    32881 tatggagtta gaaggcttgg ggacagtttt cttaggggca cctgagatgt tgctggattc
    32941 tgaagtccca gaagccaggg aggccttgga gagaggatca cgtgtcttgg tcttagctct
    33001 cagtcaggag aaattagacc atcacaaacc acagaaacca tctgatattc aggctctagc
    33061 cttgctggaa atcttggacc ccattcgaga gggagcagca gagacgctgg actatctccg
    33121 ttctcaggag gtgggactca agattatctc tggtgacaat ccagttacgg tgtccagcat
    33181 tgcccagaag gctggttttg cggactatca cagctatgta gattgctcaa aaatcaccga
    33241 tgaggaattg atggccatgg cggaggagac agctattttc ggacgtgttt cccctcatca
    33301 aaagaaactc atcatccaaa cgttgaaaaa agcgggtcat acaacggcta tgacagggga
    33361 cggggttaat gatatcttgg cccttcgtga ggcggattgt tctatcgtga tggcggaggg
    33421 agatccagca acccgtcaga ttgccaatct ggttctcttg aactcagact ttaatgatgt
    33481 tcctgagatt ctcttcgagg gtcgtcgcgt ggtcaataac attgcccaca tcgccccgat
    33541 tttcttgata aagaccatct attccttcct gttagcagtc atctgtattg ccagtgcttt
    33601 actaggtcgg tcagagtgga ttttgatttt ccccttcatt ccgatccaga ttaccatgat
    33661 tgaccagttt gtggaaggtt tcccaccatt cgttttgact tttgagcgaa atatcaaacc
    33721 tgtcgagcca aacttcctca gaagatccat gcttcgtgcc ctaccaagtg ccctcatggt
    33781 cgtgtttagc gttctttttg tgaaaatctt tggaacgagt caaggttggt ctgagttaga
    33841 aatctcaact ctcctctatt atctcttggg gtcaattggt ttcttatccg tatttagagc
    33901 ctgcatgcca ttcactctat ggcgagtcct cttgattgtc tggtcagtag gaggcttcct
    33961 agccacagct ctcttcccaa gaatccaaaa actgcttgaa atttcaacct tgacagaaca
    34021 aacgttgcct gtttatggtg tcatgatgtt ggtctttaca gtgattttca tcctgactag
    34081 tcgctatcaa gctagaaaat aaagaaagac tgcaatctgt ggattgcagt ttttttaggt
    34141 acaagattgc cagccgaaat gtggtataat aagaggtaat agagttttgg aaagtgagag
    34201 aagatgattt caaagagatt agaattggta gcttcctttg tgtcacaggg ggctatttta
    34261 ctagatgtgg gaagtgacca tgcttatctg cctatcgagt tggttgagag aggccaaatc
    34321 aaaagcgcta ttgcaggtga ggtggtggaa ggtccctatc agtctgcggt taaaaatgtt
    34381 gaggctcacg gcctaaagga gaaaatccaa gtccgtttag ccaatggctt ggcagctttt
    34441 gaagagactg accaagtgtc tgtcattacc attgctggca tgggtggtcg tttgattgct
    34501 aggattttag aagaaggttt ggggaagtta gctaatgtag agcgtttgat cctccagccc
    34561 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
    34621 gaaagaatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
    34681 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
    34741 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
    34801 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
    34861 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
    34921 ttctatggag ggagacagct gtggtctgca aattggcact ttagacaagg gtatccaaag
    34981 ggtcatggtt gccctcgata ttcgtgaaga gacggtggct gaagccattg aaaagggtgt
    35041 agacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
    35101 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
    35161 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
    35221 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
    35281 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
    35341 agatagcctt cgaatggtgc attatcaaga ggatgatttg cagaagccta tttcaagagt
    35401 agcaatttgt ggtggaagcg gacagtcttt ctataaggat gctttggcaa agggggcaga
    35461 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
    35521 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcaacact
    35581 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
    35641 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
    35701 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
    35761 aggtggccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
    35821 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
    35881 atttttatgt ggatttatta gctgatttag agaaatcagg acaagaaatc gacttttacc
    35941 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa tttggaagaa ctttatcaac
    36001 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctgaaccaag
    36061 cctcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
    36121 gtggagcgag agtagatggc caacttttag tgactcgttt gctggaagtc agtcatgtca
    36181 agctggtcaa agaaaaagtg actctgacac cgttagcatc aggctaccag attggtgaag
    36241 aggagtttga gcaggttatt ttggcgacgg gagcttggtt gggggacatg ttagagcctt
    36301 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
    36361 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
    36421 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
    36481 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
    36541 ctagagtgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
    36601 ccttctttgg gcaggtgcca gaattggcag gtgtctatgc agccagtgga ctaggttcat
    36661 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
    36721 agttgacctt ggaccctgaa aactacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
    36781 aataatactc aatgaaaatc aaagaacaaa ctaggtaact agccgcgggt tactcaaagc
    36841 actgctttga ggttgtggat agaactgacg aagtcagctc aaaacactgt tttgaggttg
    36901 tagatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
    36961 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
    37021 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
    37081 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
    37141 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
    37201 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
    37261 cagatattcg tgacacagat accctcagag atattttcaa gcaggaagaa ccgactggtg
    37321 tcattcattt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
    37381 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
    37441 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
    37501 tggaagattt cccactttca gtgaccaacc catacggtcg tactaagctc atgctagagg
    37561 aaattttgac tgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
    37621 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
    37681 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
    37741 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
    37801 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
    37861 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
    37921 aagcggtggg ccgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
    37981 cctgctactc agacccggca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
    38041 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
    38101 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
    38161 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
    38221 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
    38281 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
    38341 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
    38401 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
    38461 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
    38521 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
    38581 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
    38641 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
    38701 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
    38761 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
    38821 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
    38881 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
    38941 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
    39001 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aaataaagtg
    39061 aaaagactat aattttacat ggaaatgtgc taaactagag ggagtggatt atcgccattg
    39121 atttaggctt cctggtttcc aatcagggcg cgagttgggc aatttttaac agcctctaag
    39181 acatcctgac taggagaaat ttctttttcc agttggtcag ggtcatcgta aaaacgcacg
    39241 attccattat cgtggtaatc aaataaatca gaataagttt ggcaaagccc acaggcgata
    39301 catcgttcag gtataagtgt gattttcatg ttcatattta tattgtaata agaaaagtaa
    39361 aaaaaaacaa ggagtaaggt atggcaaaag aaccgtggca agaagatatc tatgatcaag
    39421 aagaatcaag agcagagcgt cggcatcgaa accacggagg ggcggatagg atggctaatc
    39481 gtattttgac gatcctagct agtattttct ttgtaattgt ggtggtgatg gtcatcgttc
    39541 tcatctatct atcatcgggg gggagtaatc gcacagcagc cttaaaagac tttcatgatt
    39601 ctgatgcaag tgtagtacaa atctcatctt caagcagttc tcagcctgag cagagttcag
    39661 agccagaatc tacttctagt agttcagaag aagctgctaa tcctgaagga acgattaaag
    39721 ttctcgcagg agaaggggaa gcagctattg ccgctcgtgc aggaatctcc attgctcagt
    39781 tagaggcctt gaatcctggg cacatggcta caggatcttg gtttgctaat ccaggtgatg
    39841 ttataaaaat aaaataggag ccgatatgaa aacaattcaa attgctattg atggtcctgc
    39901 ttccagcggt aagagtacgg tcgcaaagat tattgctaag gattttggat tcacctacct
    39961 tgatacagga gctatgtatc gtgcagcgac ctatatggct cttaagaacc aattaggagt
    40021 tgaagaagtc gaagcccttc tagccttgtt ggaccagcat ccaatcagct ttggacgttc
    40081 agaaactgga gaccagcttg tttttgtagg agatgtggat attacccatc ctatccgtga
    40141 aaatgaagtg accaatcatg tttctgctat tgcagcaatt cctgaagtgc gtgagaaact
    40201 ggtttctctc caacaagaaa ttgcccagca aggcgggatt gttatggatg gtcgcgatat
    40261 tggaactgtt gtattgccgc aagcagaatt gaaaattttc ctagtagctt ctgttgatga
    40321 gagagcagag cgtcgttaca aggaaaatat tgccaaggga attgaaacag accttgaaac
    40381 cctaaaaaag gaaattgctg cgcgtgacta caaggatagt catcgtgaga cttctcctct
    40441 caaacaagca gaggatgctg tctaccttga tacaactggt ttgaacattc aagaagtagt
    40501 tgaaaaaatc aaagcagaag ctgaaaaaag aatgtaaatg tagaaaagcc gatagattga
    40561 tatcggtttt tttctaaatt tgtcaaaatg ctgattttag ggtataatag ttgctgttcg
    40621 agaaattttg attttcaaag aatagtgaat gatgataagg agaaaccatg aacaatttac
    40681 caaattgtcc aaaatgtaac tcagagtatg tctacgaaga cggtgcccta ctggtttgcc
    40741 cagagtgtgc tcatgagtgg aatcctgctg aagttgcaga agtagaagaa ggtcttgtcg
    40801 ctatcgatgc caacggaaat aaattgactg atggtgatac agtaactctc atcaaggact
    40861 tgaaagtaaa aggtgcgcca aaagatttga aacaagggac gcgcgtgaaa aatatccgca
    40921 tcgtagaagg cgaccacaat atcgactgta agattgatgg ttttggtgcc atgaaactta
    40981 aatcagagtt tgtgaggaag atttaagcat gtcaaaacac tataaacttg tattttatag
    41041 ccgtatcttc ttgtttctag cggcttttac gggagtttat cttgaaatta ctaggcatgg
    41101 tggttttggg atgcttctct attacacggt tctgtccaac cttttggtaa ctatttttac
    41161 cctttatctt ctaaaggtta tgagccgtgt aggtgaaaat tggcaaaggc caagtctctt
    41221 gcgcttaaaa ggtggggtca ccatgagtat catgattacc tgtgtgattt accatttcct
    41281 cttggcgccc attgcgacta atttctatac cctagaaaat ttcctttgcc actatatcgt
    41341 tcccatctgg tttttagcgg ataccatctt ttttgacaaa cagggtcaat acaagatttg
    41401 ggatccagca gtgtggacca ttttaccctt tctgtatatg atgtttgctc tttttaatgg
    41461 cttggttcta aaactcaata ttccaaatgc caaggataat cctttccctt acttcttttt
    41521 gaatgtgaac aagggttgga atgttgtgtt taagtggtgt ctgattatct ttgttgccta
    41581 tatggtagca ggatttattt tctactttat caagcaaatc aagagaaagt catcctaata
    41641 ctcttcgaaa atctcttcaa accacgtcag tttccatctg caacctcaaa acactgtttt
    41701 gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta taagatacaa
    41761 gggattcatt ttcgaattta agaaggagtc tacaaaccaa tgaggcttct tcttttcttg
    41821 cttatttgat aactatcaaa aaaagtagaa gattaagaga aatatagaaa gagatttcat
    41881 gaaacaattt ttagaacggg ccagcatttt ggctctctcc ctcgttttga ttacctcctt
    41941 ttccatttcg agtgccctac cagccatgtt tgactattat cagggttatt ctaaggaaca
    42001 aattgagctc ttggtgagct tgccttcctt tggaatcatg atgatgttac tgctaaatgg
    42061 tttcttagaa aaaatatttc ctgagcgctt acagattagt ttgggcttgc tgattttatc
    42121 attgagcggt acagctccct tctggtacca agcctatccc tttgtctttg gaacacggct
    42181 tctctttggt ttgggtcttg ggatgatcaa tgccaaggcc atttctatta tcagtgaacg
    42241 ctaccaagga aaaaggcgaa ttcagatgtt agggctacgc gcttctgcag aggtcgttgg
    42301 agcttctctc attaccttgg ccgtcggtca gttgttggcc tttggttgga cagctatctt
    42361 tctagcctat agtgctggat ttttggtgct gcccctttat ctgctctttg tcccttatgg
    42421 aaaatcaaag aaagaagtca agaaaagagc gaaggaagca agtcgtttaa ctcgagaaat
    42481 gaaaggcttg atttttacct tagctatcga agcggcagtt gtagtttgta ccaatacagc
    42541 tattaccatc cgtattccaa gtttgatggt ggaaagagga ttgggggatg cccagttatc
    42601 tagttttgtt cttagtatca tgcagttgat cgggattgtg gctggggtga gtttttcttt
    42661 cttgatttct atctttaaag agaaactgct cctctggtct ggtattacct ttggcttggg
    42721 gcaaatcgtg attgccttgt cttcatcctt gtgggtggta gtagcaggaa gtgttctggc
    42781 tggatttgcc tatagtgtag tcttgacgac ggtctttcaa cttgtctctg aacgaattcc
    42841 agctaaactc ctcaatcaag caacttcatt tgctgtatta ggctgtagtt tcggagcctt
    42901 tacgacccca ttcgttctag gtgcaattgg cttactaact cacaatggga tgttggtctt
    42961 tagtatctta ggaggttggt tgattgtaat ctctatcttt gtcatgtacc tacttcagaa
    43021 gagagcttag gattgattcc taagtttttc ttttgatact caatgaaaat caaagagcat
    43081 agttgattga gtttggaata gtacgctgta gctgctaaaa tatttctaga aattaatttg
    43141 actttcctaa tagagttgtt catatcttat ttcaatctac tatagaaagc tagccgcagg
    43201 ttgctcaaaa tagtgttttg aggttgcaga tggaaactga cgtggtttga agagattttc
    43261 aagagtataa gatttttata cccatacaat atttgtttta ggtccttgtt tacagactaa
    43321 tttcttgata aaatagaggt tatgacgaga tataaagcaa ctatttccta tgatggttat
    43381 gcctttgctg gctttcagcg ccagcctcat gcgcgtagcg ttcaggaaga aattgaaaaa
    43441 accttgacca gattaaataa agggcaaacc attactgttc acggtgctgg taggacagat
    43501 agtggggttc atgccctggg acaggtcatt cattttgacc tgccttatca gatggatgag
    43561 gagaaactcc gttttgcctt ggatacccag tctcctgaag atattgatgt gatttcgatt
    43621 gagcttgtgg cagctgattt tcattgccgt tatgccaagc atagcaagac ctatgagttt
    43681 attgtggata gaggacgtcc caaaaatccg atgcgccgtc actatgccac ccactttccc
    43741 tacccactcg atgtggaacg aatgcagatt gcaatcaaaa agctagaggg aacccatgat
    43801 tttaccggtt ttacagcctc tgggactagt gtagaggata aggttcgcac catcacagaa
    43861 gctagtttaa tagtcgatga gacaggacaa tttttgacct ttaccttttc aggaaatggt
    43921 ttcttgtata aacagattcg caatatggtg gggactcttc tcaaaatcgg taacaaccgc
    43981 atgccagtag agcagattga tctcatcttg gagaagaagg acaggcaact tgcaggtccc
    44041 actgcagcac caaatggttt gtatttaaag gagattcgtt atgaagaata atcgtatttt
    44101 agcactttct ggaaatgata tttttagtgg tggtggactg tcagctgatt tggctaccta
    44161 taccttgaac ggcttgcatg ggtttgtagc agtgacttgt ttgacagcct tgacagaaaa
    44221 aggatttgaa gtctttccaa ctgatgatac catttttcaa catgaattag atagcttgcg
    44281 tgatgtggaa tttgggggaa ttaagattgg tcttctccct actgtcagtg tggctgagaa
    44341 ggccttggac tttatcaaac aacgcccagg agtacctgtg gtgttggatc ctgtcttggt
    44401 ctgcaaggaa acgcatgatg tagctgtcag tgagctctgc caagagttga ttcgcttttt
    44461 cccttatgtc agtgtgatta cgcctaatct cccagaagca gaattattat ccggtcagga
    44521 aattaaaacc ttggaagaca tgaaaactgc agcgcagaaa ttgcatgatt taggagcgcc
    44581 agcagtcatt atcaagggag gcaatcgtct tagtcaggac aaggctgtgg atgtctttta
    44641 tgatggacag acctttacta tcctagaaaa tccagttatc caaggccaaa atgctggtgc
    44701 aggttgtacc tttgcctcta gcattgccag tcacttgatt aaaggtgata aacttttgcc
    44761 agcagtagaa agctctaagg ctttcgttta tcgtgctatt gcacaagcag atcagtatgg
    44821 agtaagacaa tatgaagcaa acaaaaacaa ctaaaatcgc ccttgtatcc ctattaaccg
    44881 ccctttctgt ggttctaggt tatttcttaa aaatcccaac acctacagga attctaactc
    44941 ttttagatgc tggtgtcttc tttgcggcct tttactttgg tagtcgtgaa ggagcggtag
    45001 tcggaggact agcaagtttc ttgattgacc tcttatcagg ctaccctcag tggatgttct
    45061 ttagcttggt caaccatggc ttgcagggat ttttcgcagg atttaaagga aaaagtcagt
    45121 ggttaggcct tattttagca actattgcca tggtaggagg ctacgccttg ggttctactt
    45181 tgatgaatgg ctgggcagca gccctcccag aaattctacc aaatttcatg caaaatatgg
    45241 tagggatgat tgtaggattt attcttagtc aaagtatcaa gaagattaag taatactctt
    45301 cgaaaatctc ttcaaaccac gtcagcttcc atctgcaacc tcaaaacact gttttgagca
    45361 gcctgaggct agctttctag tttgcacttt gattttcatt gagtataaag aggttgagta
    45421 aaaagtattt caaataagaa aaacgcatag tatcaggtgt tgaatgaact gccccccaaa
    45481 agttagacag aaaaaatcta acttttgggg tgttttatta tgaaactaac ttatgatgat
    45541 aaagttcaga tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa
    45601 tttgggataa ataattctaa tcttaggtac atgattaaat tgattaatcg ttacggaata
    45661 gagttcgtca aaaaaggaaa aaatcgttac tattctcctg atttaaaaca agaaatgatt
    45721 aatcaagtct gacatgaagg ctggactaaa gatagagttt ctcttgaata cggtctccca
    45781 agtcgtacga tacttcttaa ctggctagca caatacagga aaaacgggta tactattgtt
    45841 gagaaaacaa gagggagagt acctaaaatg ggacgtaagc caaaaacgag acctgaagag
    45901 aggacagaat tagaatatct tcaagcagaa aatgagtacc tgagagcgga gaatgccatc
    45961 ctaaaaaagt taagagaact ccgattgaag gaggaaaaag agaaagaaga aagacagaaa
    46021 ttgttcaaga attaatgact gagttttcgt tagttcttct tctaaaatcc attaaactag
    46081 ctcgttcgac ctactactat cacttgaaac agctagataa accagataag gaccaagagc
    46141 ttaaagctga aattcaatcc atttttatcg aacacaaggg aaattatact tatcgccggg
    46201 ttcatttaga actaagaaat cgtggttatc tggtaaatca taaaagagtt caaggcttga
    46261 tgaaagtact caatttacaa gctaaaatgc gacagaaacg aaaataaagg agacgttggt
    46321 aagaaggcag agaatctcat tcaaggccaa tttgaaggct ctaaaacaat ggaaaagtgc
    46381 tacacagatg tgacagaatt tgccattcca gcaagtactc aaaagcttta cttatcacca
    46441 gttttagatg gctttaatag cgaaattatc gcctataatc tttcaacttc acccaactta
    46501 gaacaagtac aaacaatgtt ggaacaggca ttcacagaga agcactacga gaatacgatt
    46561 ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcggtt cctagagagt
    46621 aagggaattc aagcatccat gtcacgcaag ggaaacagcc cagacaatgg tatgatggag
    46681 tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc gtttcagtcg
    46741 cttaagcaat tggaacaagc cattatagac tatattgatt attacaacaa caagagaatt
    46801 aaggtaaaac taaaaggact tagccctgtg caatacagaa ctaaatcctt cggataaatt
    46861 aattgtctaa ctttttgggg ggcagttcat tctacaccca ctattatgcg ttttattgtg
    46921 ggaagatttt cctcattttc tagtgaaatt gaactttttc taacatcttt tgatagatga
    46981 cttcttaatc aattatcatt tccattgttg tttcttgggg tttcatccct tgtctttgat
    47041 aaaagcggag agcaccctcg ttatcattcc agacacttag ggttagatta ttgcagccaa
    47101 tttctttagc ataatagcag aaaaatgaca ataaaatagc ccctagatat tttgaaagga
    47161 aagcataggg gctatatagt ttaatcaaaa taaagcaaat ctttgctggt gcttgtaaag
    47221 aggtcgaagc catccttggt aacaacaccg cagtcttcaa tacgaacacc gactttacca
    47281 gggatataga tacctggttc aacagagaag cacatgcctt cttcgatgac catgtcgttt
    47341 ccttccatga tagatgggaa ttcatggaca tccataccga taccatgccc gagacggtgg
    47401 ttgaagtact caccataacc agctttttcg atgacctcac gggcagcgcg gtccacttca
    47461 tgagcagtca cacctggctt gataaagtca agagcagctt gttgggcttc aagagtcaag
    47521 ttgtaaatat ctttcttgaa ttggtctggt ttgccgacag cgactgtacg agtcatatct
    47581 gacgcatagc cattgaccag aacacccagg tcaaagagga gaagagcatc attttcaacc
    47641 ttattagctg ctggaatgcc gtgtggattc gcagcattat caccagtcaa gaccatggta
    47701 tcaaagctca tttcataacc ttcacgtttc atggcaaagt cgatttgtgc gatgatatct
    47761 gtctcagtct tatcaagaga aatattgtca aaaccaacat gaacagcctt gtcagcataa
    47821 agacctgcaa ccatcatttt ttgcacttca tcagctgatt tgatgaggcg catgcgttgg
    47881 atacgaggag tgaggttgtc aaactcagca gtctcaaaaa ctgttttcaa accatggtat
    47941 ttggtcaaga tgagattgtc aaactcaaca gcgacacgtt tgaagtcaag ttgtggaaga
    48001 gcatgtttga ttttttgcca tggattttca gaatcgacat agcccactac tgggaaggaa
    48061 acggtgctac ttgcacgttc tacttcaaga gctgggacaa agaggagagg ttcctgatcc
    48121 gctaggacaa agaggaacat ttggcgttca tggggatcac tgtaaaaacc agtgaggtaa
    48181 ttgattgtga cggggtcaga tacgacagcg acgtctagtt tttctgattc aagatatgtt
    48241 aggatttgtt gtaatttaga catatgctac cttctttcta cccctctatt ttggcaaaaa
    48301 atgagagaaa atgcaaggga gaagggtaaa agaaaagaca aaaaactccg acaagataac
    48361 ggagttcttt gatatcattt tcctttgttt aagaaaagtc agccttgctt ttgacgtcac
    48421 tgtactcttc agcgatttct tggctgagga tatcctcata ggcagggagt tggatatcct
    48481 gaccatattt cttcttgagg gcagtagtaa ctaggcgata agccagattg gcattacgag
    48541 agaggatagg cccgtggaag taggaaccaa agacattctt ataatgaacc ccttcaccga
    48601 ccttttcttc gttgtttcca tttccataga caacctgtcc cagcggtttt tggtcatcag
    48661 agaggaaggt acggccttgg tgattttcaa atccatagta ggtttcatcg aaatcttcat
    48721 tgtgaatctt gatgtcaccg ataaaacggt tattggtctg gttgagcgtg tagtgtccca
    48781 tgacccctag cccttcgata cgttttcctg aagcttcaac ataatattga cccaatagtt
    48841 ggaaaccacc gcagatagcc agaactacac cgtcgttttg gatgtagttg tcaatgctct
    48901 cttttttagc aggtaggtcg tctgcaatga tactttgttc aaagtcttga ccaccaccga
    48961 aaaaggcgat gtcgtagtga ttttcatcaa agtcatcatg gagagaaacg atgtcaacgg
    49021 tcacatgggc tcccagtttt tcagccacat acttgagcat gaggatgttt ccattgtccc
    49081 cgtaggtatt catgagattt ccgtagaggt gggcaatgtt gagctgatag gggtaattgc
    49141 catcttttga ggaaagtgaa gtataaacca ttagttcatc tcctttctaa caatctgacg
    49201 actagccagc agttcacgaa attccagcat ggcagtataa gttgccagaa tataggcatg
    49261 cttgcagtct tgattctcaa tggtcttgag aacttgctcc agattactcg tttcagtgat
    49321 tttctcagct ggatagccag tcactcggag gcgacgagcg atttcagaat gacgaacacc
    49381 accagcgttg atttcaggaa tgtccatgtc agtgatttgt tcaaagtctg catcccagat
    49441 ccagctagtg tcaattccat ctgcatagtt ggcattaagg aggacagata ggctaaatgg
    49501 ataaggtgct agtttgatca tttcgatagc ttgggttgca ccgactggat ttttaatcaa
    49561 gacaagggta cattccttgt caccgatatg aaaggtttct tggcgtccaa agacagcacg
    49621 gctcttgtca aatccctgtt tgatgagttg cgaatcggca cctaggaaac gggcgatggc
    49681 cacagcagct agggcgttat agatattata gagcccgccg atttggatac cgtattcttg
    49741 gccgtctatg acaaagcgag agcgattgtt ggtcaactca accagttttg tcaaacgata
    49801 gtcgagatca ggacgtttgc atccacaacc ttcacagata taggcaccca agtttgcata
    49861 ggtattatgc tcatatttga ggatgccttg gcagtcagga cagagaatcc cttcggtatt
    49921 gtagtgagcc agttgggctg gtcctttttc caagtcaaaa ccaaaatact ctatagggtt
    49981 tggaatagtt ggcttgtaga aaagtggact gtctccgtta aggagaacag tagcagttgg
    50041 aactttccga atggcttcca atatcatgtt ataggtagta tagatttcac cgaaacggtc
    50101 catctggtca cggaagatat tagtaatgac aaaaagacta ggctggatat agtcacagat
    50161 acgagataga ctggcttcgt caatttcgag gacggcaata tttttcccag tttttgaaga
    50221 tttggctgtt aggaaggttg ttgcaatccc tgtaatcatg ttggcaccgc ttgggttggt
    50281 tagaacttga ccataaacct cttttaaaat gccgacagtg agggcagttg tcagggtttt
    50341 tccatttgtt ccagtgacaa cgacaatctc gtagttctta gctaggtttt gtaaaatatc
    50401 tttatcaaat tgaagggcga ctttacctgg gagcgtactt ccacggccaa gacggcttaa
    50461 aatgaagtgg gaagaacgcc cagcaagaag gcccaaagta gtttttaagt tcatgtttct
    50521 attatatcat aaaagaggag aaagacagat ttgagattcc gcagaagtaa aaacagccca
    50581 aagagggctg ttcgatacga ttaaatctca acttaaatcg caaacaagtc attcaagttc
    50641 tcagccaagg ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg
    50701 tccatagcaa cagtgatgat gttgatgatt tcttgagaac cttctgagaa gatgcttgct
    50761 ccaagaattt cttttgtttc agtattgaca acagctttga aggcaccgcg aaggtctcca
    50821 tttacgtgac cacgaggcat tgctgcaacg gggatttcct taacagcgta tggaagtttc
    50881 aaatcagctg cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata
    50941 gtatttggca cattgagacg gtcttcaagt gtgtagctgc catctccagc aaggtagctg
    51001 taaacaacac ggaagtcatc aagtgaaatg taagtaaatt gaaggtcacc gttgacatct
    51061 ccaactgcaa agacaccagg aacgtttgtt tgacagtgtt tgtctacttt aatagcacca
    51121 cgttcagtta gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt
    51181 ccagttgcgt agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact
    51241 tggtcaccat cgtttttgat ttcagtagta tggatatttt gaagcaattc aatgccatct
    51301 tcttccatgt attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta
    51361 tccaaggcat ctaggactgt gaccttgctt ccaagtttgt tgtaaaggcc ggcaaattca
    51421 agaccgatat ttccgccacc aaggattcca agtttttcag gtaatttgtc caagctttgg
    51481 atacctgttg agtcaaagat gtttttgctt gtagcaagtc cagggattgg caagacgttt
    51541 gaaacagcac cagtgttgat gacgattgtt tcagcagtca gttctttctt ttcatcacca
    51601 gcttggattt cgatgacttt atttgaaagg aagtgagctt ccgcatcaaa gatatctacg
    51661 cctgtaccag caacagtcgc atagttttta ccgttgaggc gaccagtgat cgtgttttta
    51721 gtagcaatga cttcttcaaa agacaagtcc ttttcagcag caactagcaa ggttttagtt
    51781 gggatacaac caatgttgat acaagttcca ccgtacatag ccttgctgcg ttcaacgagg
    51841 gcaacttttt tgccagctga agccaattta cctgctagtg ttttaccagc tttaccaaat
    51901 ccaataacaa ttaaatcgta tgttaacatt tatcttcctc ctattcgaat ttcattctag
    51961 cacaagaaaa aaacttttgc acaattctgc tacggaaaag acagaaaaag ataaaaacgc
    52021 tttccagaca aaaaactagt aattttttga caagcttgat aaactaaaat cctatctatt
    52081 tttatataag atagaataaa tgttcgaaaa taggaggttt tatgaaatcg aatcgttata
    52141 ttattgcctt tgctggggtc attttacact taatgctggg ttcgacttat gcttggagtg
    52201 tttatcgtaa ccctattatt gaaaaaacgg gatgggatca ggcttctgtt gccttcgcct
    52261 ttagtctagc aatcttttgt ttgggtttat cggctgcatt tatggggcgt ttggtagaaa
    52321 aatttggtcc gaaagtcatg gggagtctat ctgcttttct atacgcaggt ggaaatatct
    52381 taacaggatt tgcaatagac cgtcaggaac tgtggttgtt gtatctagct tatggcattt
    52441 taggtgggct tggtttggga gcaggctata ttacccctgt gtcaacgatt ataaaatggt
    52501 ttcctgataa acgtggtctc gcaacaggtt tagcgattat ggggtttggt tttgcttctt
    52561 tattgactag tcccatagcg caacacctta tcgcaggggt agggattgta gaaacttttt
    52621 atattttagg agcaagttac tttattatca tgctcctagc ttcacaattc attaagcgtc
    52681 caaatgagca agagcttgca attttatctt cttcagggaa agaaaaaaca gcctctttga
    52741 cgcaaggaat ggctgcaaat caggctctaa aaagcaatcg gttttatatg ctttggatta
    52801 ttttctttat caacatagct tgtggtttag gcttaatttc agcggcatcg ccaatggcac
    52861 aggagatggc tggcttgtct acaagtcatg cagcagtaat ggtgggtgtt ttggggattt
    52921 tcaatggatt tggtcgcttg ctctgggcga gtttgtctga ctatatcggt cgccctctaa
    52981 cctttagtat attactgctt gtcaatcttt tcttttctct ctcactttgg ctctttacag
    53041 attccgtttt atttgtagtt gctatgtcta ttttgatgac ttgctatgga gctggttttt
    53101 ctttgattcc agcttatctc agtgatattt ttggaaccaa ggaattggcc gctctgcatg
    53161 gttatatttt aacagcttgg gcaatggctg gtttagcggg acctatttta ttagcagaga
    53221 cttataaaat ggctcattcg tacacacaaa ccttgttcgt ttttctcatt ttatacagta
    53281 tcgccttggc tttgtcttat tatctaggtc gttcaatcaa aaaagaaagt caaaaaccgc
    53341 ttacatgatt ttctgtagaa atggggctat cttttgctct ggtcttgtgt tatactagat
    53401 aggttgcaaa gaaaacagta cttttctttt gtggaaaaga agcaacacga ttttatatct
    53461 agttatatga aaatacgtca taaaaagaaa agtataaact aagccctata gggtggcttc
    53521 gcaccacctt tagaaagaag aataacgtga aatttaatga attaaacttg tctgctgatt
    53581 tgctagcaga aattgaaaaa gctggttttg tagaagctag tcctatccaa gaacaaacta
    53641 ttcctttggc ccttgaaggc aaggatgtta tcggtcaagc tcagactggt acaggaaaaa
    53701 ctgcagcctt tggcttgcct acccttgaaa aaatccgtac agaagaagcg actatccaag
    53761 ctttggtcat cgctccaact cgtgaactag ctgtccaaag tcaagaagaa ctcttccgct
    53821 ttggtcgtag taagggagtc aaagtccgtt cagtatatgg cggatcaagc attgaaaaac
    53881 aaattaaggc tcttaaatct ggtgcccata tcgtggtggg aactccaggt cgcctcttgg
    53941 acttgattaa acgcaaggcc ttgaaattac aagacattga aacccttatc cttgacgaag
    54001 cggatgaaat gcttaacatg ggcttccttg aagacatcga agccattatt tcccgtgtac
    54061 ctgagaaccg tcaaactttg cttttctcag caactatgcc agatgccatc aaacgtatcg
    54121 gtgttcagtt tatgaaagcc cctgaacatg tcaagattgc ggctaaggaa ttgacaacag
    54181 aattggttga ccagtactat atccgtgtta aggaacaaga aaaatttgac accatgactc
    54241 gtctcatgga tgtggcacaa ccagaactcg ctattgtatt tggtcgtacc aaacgccgtg
    54301 tggatgaatt gactcgtggt ttgaaaattc gtggcttccg tgcagaagga attcatggcg
    54361 acctagacca aaacaaacgt cttcgtgtcc ttcgtgactt taaaaatggc aatcttgatg
    54421 ttttggttgc gacagacgtt gcagcgcgtg gtttggatat ttcaggtgtg acccatgtct
    54481 acaactacga tattccacaa gatcctgaga gttatgttca ccgtatcggt cgtacaggtc
    54541 gtgctggtaa gtcaggtcaa tctattactt ttgttgctcc aaacgaaatg ggttaccttc
    54601 aaatcattga aaacttgact aagaaacgca tgaaaggtct caaacctgca agtgtagaag
    54661 aatccttcca atcaaaaaaa caggtagctc tcaagaaaat cgaacgtgat tttgcagatg
    54721 aaaccattcg tgccaacttt gagaaatttg gtaaggatgc tcgcaaattg gctgctgagt
    54781 ttactccaga agaattggca atgtatatct tgagtctgac agtccaagac ccagatagcc
    54841 ttccagaagt ggagattgca cgtgaaaaac cactaccgtt taaaccatca ggtaatggtt
    54901 tcggtggtaa agctaaggga ggtcgtggag gccgtcgtgg ggacgaccgt cgagagcgtg
    54961 atcgccgtgg caatggtcgc cgtgatgagt tcaaaaaagg aagtcgtggc aacgatcgtt
    55021 ttgataagga aaaacgttac cgtaaggata ataaaaaacc acgcaatact ttaaacgaaa
    55081 agcaaacagg ctttgttatt cgtaacaaag gtgataaata agaaaaagcg gttcaaaatg
    55141 aatcgctttt ttatataagg agaccgaatg tgaaaaagac aaataaaatt attatattat
    55201 cttttataat attatgatac acaaaaatag gcaacttgtc aatagaaaag gaacaattta
    55261 attaaaaata ttctggtttt taattaaatt gtaagtcaat gcaagtcaat aaggaatttt
    55321 cagataatta ttgaaaaaga gacgttttta tgttataatg atagcgatta aattcgaggt
    55381 gaaaaatggc acatttatta gaaaaaacta gaaaaattac atcaattttg aaacgctcag
    55441 aggagcagtt gcaggatgag cttccttaca acgctattac gcgtcagtta gcggatatta
    55501 ttcattgcaa tgcctgcatt atcaatagta agggacgtct gcttggctat tttatgcgtt
    55561 ataaaacaaa tacagatcgc gtagagcaat tcttccaaac taagattttc ccagatgact
    55621 acgttcaagg ggctaatatg atttacgaaa cagaagcaaa cttacctgtt gagcatgata
    55681 tgagtatttt ccctgttgag agtagagatg attttccaga tggcttgacg actattgcac
    55741 cgattcatgt atcggggatt cgccttggtt ctttgattat ttggcgtaat gataaaaaat
    55801 tcgaagatga ggacttggtt cttgttgaga ttgccagtac cgttgttggg attcagcttc
    55861 ttaacttcca acgtgaagaa gatgagaaaa atattcgtcg tcgtactgct gtcaccatgg
    55921 cggtcaatac cctttcttac tccgaactcc gtgctgtttc agcaatttta ggggaattaa
    55981 atggaaatga agggaagttg actgcgtcag tgattgcaga tcgtatcgga atcactcgct
    56041 ctgtgattgt caatgctctt cgtaaacttg agtctgcggg gattattgaa agtcgctcac
    56101 ttggaatgaa gggaacctat cttaaggtct tgatttcaga tatttttgaa gaagtgaaga
    56161 aaagagatta ctaatgacaa aggctttaat ttcgattgat tatacagaag attttgttgc
    56221 tgatagtggg aaactaacag caggtgctcc agctcaggcg atttcggatg ccatcagcaa
    56281 ggtaactcga ttagcttttg aacgaggaga ttatatcttc tttactattg atgctcatga
    56341 agaaaacgat tgtttccatc cggaaagtaa gttatttcct cctcataatc tgattgggac
    56401 gagtggacgg aatttatatg gagatttggg gatcttttat caagagcatg gttcagacag
    56461 tcgtgtcttt tggatggata aacgccatta ctcagctttt tcagggactg acctagatat
    56521 tcgtttgaga gagcgtagag tgtctaccgt tatcttaaca ggtgtcttga cggatatctg
    56581 tgtcctacat acagctatag atgcctataa tctaggatat gacatcgaga ttgttaaacc
    56641 agctgttgct tccatctggc ctgaaaatca tcaatttgcc ctaggtcatt tcaaaaatac
    56701 actcggagct aagttagtag atgaaaatct aaatgaactt tctgagtaac ctggttggtg
    56761 aaaatgaaaa aatttgaaaa aagtgttgac aagcatccca aaagttgata tactagtaaa
    56821 gtaatcgacg cggggatggc ggaattggca gacgcgcagg actaaggatc ctgtgaccgc
    56881 tttaggtcgt gagggttcaa gtccctctct ccgcatagga aaagagctag ctaaagctag
    56941 ctcttttgta tttctctaaa aaattagaat ccagtcaaat gtagtggaga atcagcgaaa
    57001 atatgggaaa actgatcctt gtttctgctt ttgtcataga agaataataa agattatctt
    57061 cttcaaattc tccgatattc tctaaagttt tgtgcaagtt gcacagaact tttttatttt
    57121 tttggtcatc ttgccataga aatataaagc gttttcatct ataatataat tatcaaaaga
    57181 taaaaggagt tcacctcatg gtagaattga atcttaaaaa tatttacaaa aaatatccaa
    57241 acagcgaaca ctattcagtt gaagatttca acttgaacat caaagataaa gaatttatcg
    57301 ttttcgtagg accttcagga tgtggtaaat caactacact ccgtatgatt gctggtcttg
    57361 aagacattac agaaggtact gcatctatcg atggcgtggt tgtcaacgac gtagctccaa
    57421 aagaccgtga tatcgccatg gtattccaaa actacgctct ttacccacac atgactgttt
    57481 atgacaacat ggctttcggt ttgaaattgc gtaaatacag caaagaagac attaacaaac
    57541 gtgttcaaga agcagctgaa atacttggat tgaaagaatt cttggaacgt aaaccagctg
    57601 acctttcagg tggtcaacgt caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga
    57661 aagtattctt gatggacgaa cctttgtcaa acttggatgc caaacttcgt gtatcaatgc
    57721 gtgctgaaat cgctaaaatt caccgtcgta tcggagctac aactatctat gtaactcacg
    57781 accaaacaga agcgatgaca cttgcagacc gtatcgttat tatgtcagct actaagaacc
    57841 ctgctggtac aggtactatc ggacgtgtag aacaaatcgg tactcctcaa gaagtttaca
    57901 aaaatccagt taacaaattt gttgcaggat tcatcggaag cccagctatg aatttcatca
    57961 acgtgaaatt ggttggtagc gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag
    58021 gagcattgaa agttcttcgt gaaaaaggct acgaaggaaa agaattgatc tttggtatcc
    58081 gtccagaaga cgtgaatgca gaacctgctt tccttgaaac attcccagac tgtgttgtaa
    58141 aagcgactat ctctgtatca gaactgcttg gttcagaatc tcacctttac tgccaagttg
    58201 gtaaagacga gtttgttgca aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag
    58261 ttgagcttgg atttgacttg aacaaagcac acttcttcga tgtagaaact gaaaaaacaa
    58321 tctactaaaa taaataaaat tcaaagcact acaagaaaag atatctcttt atcaattgta
    58381 gtggagagat atcagttaat ctagggagag aaacaaaatg cttctctcct ttttgctagg
    58441 gaagtcatat tatgcatcta tattgtgatg ctctttaata ctcttcgaaa atctcttcaa
    58501 accacgtcaa cgtcgccttg ccgtacgtat gattactgat ttcgtcagtt ttatctgcaa
    58561 cctcaaagat gtactttgag cagcttacgg ctagtttcct agtttgctct ttgatttcca
    58621 ttgagtatta tttgtgggta ccatctacaa gtgaagctat atgcgtaaac tacgtgagca
    58681 attgaattcg aactagagag gtaataataa atttatgcta tagttatggt gacttgtatg
    58741 cttttgattc tagtttatca aataatagat tagaattgtc agataatatc attttgtgtt
    58801 ataatgaaga aaaaacagag gtgttcaaat gtcagaagca ggtcataagt ttttagcaaa
    58861 attggggaaa aaacgcttac gtccaggtgg aaagcgtgcc acagattggt taattgcaga
    58921 aggaggattt tcaaaagaaa agagaatact agaggttgcg tgtaataggg gaactacagc
    58981 aattgagttg gcacagcgtt ttggttgcaa gataactgct gttgatatgg atgctcaagc
    59041 tttagaagtg gctaaaaaat ctgctggaac ggcaggtgtt gctcatttaa tcagttttga
    59101 aagagcaaat gcaatgaaac ttccttatca agatgctagt tttgatattg ttataaatga
    59161 agctatgctg actatgcaag ccgatcaagc taagaaaaaa tgtgtaatgg aatatctaag
    59221 ggtattaaaa cctggaggtc ttctcttgac acatgatgta cttcttaagg aagctaaaga
    59281 gtctatcaga caggaattat cacaagcaat tcatgtaaat gtaggtcctt taactcaaga
    59341 tggttgggaa caggtgatga tagaatcagg ttattgtgat gtgaaagcat tgactggtga
    59401 aatgacatta atgaaattat cgggtatgat ttatgacgaa ggtttgctag gaactttgaa
    59461 aatttgtgta aatgcttgta aaaaggagaa tagaaagcag tttttaacta tgtataaaat
    59521 gtttgctaag aataaacaga aattgggctt tattgcgatg gctagttata aatcgtcaaa
    59581 acgttagata attattgaag ttaacttttc cttttttctt tcttaaaaaa tatgctataa
    59641 tagagagtaa aaaactttga aagaaagaaa aaagatgaat ttaaaagatt acattgcaac
    59701 aattgaaaat tatccaaagg aaggcattac cttccgtgat attagtcctt tgatggctga
    59761 tggaaatgct tatagctacg ctgttcgtga aatcgttcag tatgctactg acaagaaagt
    59821 cgacatgatc gtgggacctg aagctcgtgg atttatcgtg ggttgtccag ttgcctttga
    59881 gttgggaatt ggttttgcgc ctgttcgtaa gccaggtaaa ttgccacgcg aagttatttc
    59941 tgctgactat gaaaaagagt acggtgtcga taccttgact atgcacgcgg atgccattaa
    60001 gccaggtcaa cgtgttctta ttgtagatga ccttttggcg acaggtggaa ctgttaagac
    60061 aactatcgag atgattgaaa aacttggtgg tgttatggca ggttgtgcct tccttgttga
    60121 attggatgaa ttgaacggcc gtgaaaaaat tggtgactac gattacaaag ttcttatgca
    60181 ttattaatga aaacagtccc tagggctgtt ttctctacac taggatataa aaatagacta
    60241 taactagtta gagaaaaact ataattgaaa actatatctt cttacagtat aataaaagga
    60301 ctaagtgttt gagatttgtc ttcaaacata tgcaattatt cctgaaagag tacagttagg
    60361 agagggttat gccgattcga attgataaaa aattgccagc tgttgagatt ttacggacag
    60421 agaatatctt tgtcatggat gatcaacgtg ctgcccacca agatatccgt cctttgaaga
    60481 ttttaatttt aaatctcatg ccacagaaaa tggtcacaga gacccagttg ttgcgccact
    60541 tggctaatac acccctacaa ctggatattg attttctcta tatggagagc caccgttcta
    60601 aaacaactcg ttcagagcac atggagacct tctataaaac ttttcctgaa gtcaaggatg
    60661 agtattttga tgggatgatc atcacgggtg ctccagttga gcatttacca tttgaggaag
    60721 tggactattg ggaggaattt agacagatgc ttgagtggtc taagactcat gtctattcga
    60781 cccttcatat ctgttggggg gctcaggctg ggctttatct gcgctatggt gtagaaaaat
    60841 accagatgga cagtaagcta tcaggtattt atcctcagga caccctaaaa gagggtcacc
    60901 ttctatttag aggctttgat gatagctatg tatcccctca ttcacggcac acggagattt
    60961 ctaaggaaga ggtcttaaac aagaccaatc tcgagatttt atcagaagga cctcaggttg
    61021 gggtttctat tttggccagt cgtgatttac gagaaattta tagttttggt catttggagt
    61081 atgaccgtga taccttggca aaagagtatt ttcgagatcg tgatgcaggt ttcgacccac
    61141 atattccaga aaattacttt aaagatgatg atgttaatca ggtaccttgt ctttgttggt
    61201 cttcatctgc agccctcttt ttcagtaatt gggtaaacca tgcggtctat caggagacgc
    61261 cttttgactg gagaaagata gaagatgatg catctgcata taggtattta taagaggaat
    61321 tatgacatat ttagacgctt ttaaatcagg taccttggtt ttaccgagtg ccctgctctt
    61381 gcattttaag gaactctttc cttctagcga cgattttctg gtttggcaat ttttctattt
    61441 gcaaaatacg acaggcttag aagaaatatc gccaagccag attgctgaaa ggattggcaa
    61501 ggaaatttcg gatgtcaacc agtccatttc taatctgacg gaaaggggac tgctccagta
    61561 tcgtactatc gaattaaatg gcgaaattga attgctcttt gatgctagtt tggccttgga
    61621 acgtttggat gacctgtttg gagcagttca ttcaagttca gaccagctaa caccacaaaa
    61681 ccagctcaag gatttggtgg aaaccttcca gcaggagttg ggacgattgt tgacgccttt
    61741 tgagattgag gatttgacca agacactaaa ggaagatgga accagtgctg acttgattaa
    61801 ggaggctctt cgtgaagctg ttttgaacgg aaaaccaaac tggaagtaca ttcaggcgat
    61861 tttgagaaac tggcgccatg aaggaatcaa gagtgtggct caaattgagg ccaagagagc
    61921 agaaagagaa gcaagcaatc ctcagttgac acaggtatct gcagatttca taaatgccat
    61981 ggatctctgg aaggattaat ccatgcaagt aggcttgaaa tccgagtaag atttgcaagc
    62041 tgtgtataat tgtgatagaa taaatagaaa ataaattgaa aaaagaggta tgtgaaatgt
    62101 cacgtaaacc atttatcgct ggtaactgga aaatgaacaa aaatccagaa gaagctaaag
    62161 cattcgttga agcagttgca tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg
    62221 ctgctccagc tcttgatttg acaactgttc ttgctgttgc aaaaggctca aaccttaaag
    62281 ttgctgctca aaactgctac tttgaaaatg caggtgcttt cactggtgaa actagcccac
    62341 aagttttgaa agaaatcggt actgattacg ttgttatcgg tcactcagaa cgccgtgact
    62401 acttccatga aactgacgaa gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta
    62461 tgcttccaat catctgttgt ggtgaatcac ttgaaactta cgaagctggt aaagctgctg
    62521 aattcgtagg tgctcaagta tctgctgcat tggctggatt gactgctgaa caagttgctg
    62581 cctcagttat cgcttatgag ccaatctggg ctatcggtac tggtaaatca gcttcacaag
    62641 acgatgcaca aaaaatgtgt aaagttgttc gtgacgttgt agctgctgac tttggtcaag
    62701 aagtcgcaga caaagttcgt gttcaatacg gtggttctgt taaacctgaa aatgttgctt
    62761 catacatggc ttgcccagac gttgacggtg cccttgtagg tggtgcgtca cttgaagctg
    62821 aaagcttctt ggctttgctt gactttgtaa aataatcagt aagtagcaaa agctaggtgg
    62881 aacagcattc agatgtctgt tacatttttt ataggagaga aagattgaaa acaaaaattg
    62941 gattagcaag tatctgttta ctaggcttgg caactagtca tgtcgctgca aatgaaactg
    63001 aagtagcaaa aacttcgcag gatacaacga cagcttcaag tagttcagag caaaatcagt
    63061 cttctaataa aacgcaaacg agcgcagaag tacagactaa tgctgctgcc cactgggatg
    63121 gggattatta tgtaaaggat gatggttcta aagctcaaag tgaatggatt tttgacaact
    63181 actataaggc ttggttttat attaattcag atggtcgtta ctcgcagaat gaatggcatg
    63241 gaaattacta cctgaaatca ggtggatata tggcccaaaa cgagtggatc tatgacagta
    63301 attacaagag ttggttttat ctcaagtcag atggggctta tgctcatcaa gaatggcaat
    63361 tgattggaaa taagtggtac tacttcaaga agtggggtta catggctaaa agccaatggc
    63421 aaggaagtta tttcttgaat ggtcaaggag ctatgatgca aaatgaatgg ctctatgatc
    63481 cagcctattc tgcttatttt tatctaaaat ccgatggaac ttatgctaac caagagtggc
    63541 aaaaagtggg cggcaaatgg tactatttca agaagtgggg ctatatggct cggaatgagt
    63601 ggcaaggcaa ctactatttg actggaagtg gtgctatggc gactgacgaa gtgattatgg
    63661 atggtgctcg ctatatcttt gcggcctctg gtgagctcaa agaaaagaaa gatttgaatg
    63721 tcggctgggt tcacagagat ggtaaacgct atttctttaa taatagagaa gaacaagtgg
    63781 gaaccgaaca tgctaagaaa atcattgata ttagtgagca caatggtcgt atcaatgatt
    63841 ggaaaaaggt tattgatgag aacgaggtgg atggtgtcat tgttcgtcta ggttatagcg
    63901 gtaaagaaga caaggaattg gcgcataaca ttaaggagtt aaaccgtctg ggaattcctt
    63961 atggtgtcta tctctatacc tatgctgaaa atgagaccga tgctgagaat gacgctaaac
    64021 agaccattga acttataaag aaatacaata tgaacctgtc ttaccctatc tattatgatg
    64081 ttgagaactg ggaatatgta aataagagca agagagctcc aagtgataca gacacttggg
    64141 ttaaaatcat caacaagtac atggacacga tgaagcaggc gggttatcaa aatgtgtatg
    64201 tctatagcta tcgtagttta ttacagacgc gtttaaaaca cccagatatt ttaaaacatg
    64261 taaactgggt agcggcctat acgaatgctt tagaatggga aaacccttat tattcaggag
    64321 aaaaaggttg gcaatatacc tcttctgaat acatgaaagg aatccaaggg cgcgtagatg
    64381 tcagcgtttg gtattaagcg atgatttgaa agagggatgt gatagtagca ccctcttttt
    64441 ctttgtttta tgatagttca tcctcgagta aattcaagat cttgctcgga aatgaagctt
    64501 atatagtaga ttgaatatag acaaatacct tgtgattggt aaaacatttt agaaattcat
    64561 ttacctttcc taatcgactt ggtttcatct tatttcaatc tattatagta ttggggaatt
    64621 tcttcaaacc acatcagctt ggtcagttct acctgcgacc tcaaaacttg tgctttggtc
    64681 aagctgggtt tagtttccta gtttgctgat ggatttccat tgactataag catccaaccc
    64741 tctttttgtc ttctaaagaa ttcttaaatt atcagtctat tgcaactttt ctcatataag
    64801 ttctttgtct tgctatttgt tttccttagt agtatactaa ggtagtaatc attaagaagt
    64861 ggttacaaaa aataatgaat gaggtaaaga aaatggtaga attgaaaaaa gaagcagtaa
    64921 aagacgtaac atcattgaca aaagcagcgc cagtagcatt ggcaaaaaca aaggaagtct
    64981 tgaaccaagc tgttgctgat ttgtatgtag ctcacgttgc tttgcaccaa gtgcactggt
    65041 atatgcatgg tcgtggtttc cttgtatggc atccaaaaat ggatgagtac atggaagctc
    65101 ttgacggtca attggatgaa atcagcgaac gcttgattac actcggtgga agcccattct
    65161 ctacattgac agagttcctt caaaatagtg aaatcgaaga agaagctggt gaataccgta
    65221 atgttgaaga aagcttggaa cgtgttcttg ttatctaccg ttacttgtca gaacttttcc
    65281 aaaaaggttt ggatgtcact gatgaagaag gtgacgatgt gacaaacggt atctttgcag
    65341 gcgctaaaac tgaaacagat aaaacaattt ggatgcttgc agccgaactt ggacaagcac
    65401 ctggtttgta agaaataagg aaacatagat aaatctgtag gaaatttctt acagattttt
    65461 tctattttgt aagctattcc aaaccagtct ttttttgagt tttttgataa aatagtacta
    65521 tcagtgaaaa ggatggaagc atgactaaga aaatcgtagc tatttgggcc caggatgaag
    65581 agggtgtgat tggtaaggaa aatcgtctgc cttggcattt gccagcagaa ttgcagcact
    65641 ttaaagaaac aactctgaat catgctatct tgatggggcg tgtgaccttt gatgggatgg
    65701 ggcgtcgctt gcttccaaaa cgggaaaccc tgattttgac gcgtaatccg gaagaaaaga
    65761 tagatggggt tgctactttt caggacgtcc agtctgttct tgactggtat caggatcaag
    65821 aaaagaatct ctacattatc ggtgggaagc aaatttttca ggcttttgaa ccttaccttg
    65881 atgaagtgat tgtcactcac attcatgctc gggtggaagg agatacctat ttccctgaag
    65941 agcttgactt gtctcttttt gagacagttt caagcaaatt ttacgccaaa gatgagaaga
    66001 atccttatga ttttaccatc caataccgca agagaaagga agtctaatgg aacggagttt
    66061 atttggtcta ttcacggctt ttctgtgttt catctgcttt ctggcaggag cacaggcttt
    66121 tcgtaaaaag cgttacgggc tttctatcct cctttggtta aatgccttta ccaatctggt
    66181 caatagtatt catgcttttt acatgacctt attttagata gaatgacagt atagaatgga
    66241 aggaaatcat gtctacaaat agaaaaaatg atatgatggt ttattgctca ttttgtggca
    66301 aaaaccaaga agaagtacaa aaaataattg ctggcaacaa tgcttttatt tgtaatgaat
    66361 gcgtggagtt agctcaggaa atcattcgag aagaattggt tgaggaagtc ttggcagact
    66421 tgtctgaggt gccaaaacca attgaactcc tccatatctt gaaccactat gtaattggtc
    66481 aagatcgtgc caagcgtgcc ttggcagtgg cggtttataa ccactacaaa cgcatcaatt
    66541 tccacgatac acgcgaagag tcagaagatg tggatttgca gaagtcaaac attttgatga
    66601 ttggcccaac tggttcaggg aaaactttcc ttgcccagac cttggctaag agcttgaatg
    66661 tgccttttgc tattgcggat gcgacagctc tgacggaggc tggttatgtg ggtgaggacg
    66721 tggaaaatat cctcctcaaa ctcttgcagg ttgctgactt taacatcgaa cgtgcagagc
    66781 gtggcattat ctatgtggat gaaattgaca agattgccaa gaagagtgag aatgtgtcta
    66841 tcacacgtga tgtttctggt gaaggggtgc aacaagccct tctcaagatt attgagggaa
    66901 ctgttgctag cgtgccgcct caaggtggac gcaaacatcc acaacaagag atgattcaag
    66961 tggatacaaa aaatatcctc ttcatcgtgg gtggtgcttt tgatggtatt gaagaaattg
    67021 tcaaacaacg tctgggtgaa aaagtcatcg gatttggtca aaacaataag gcgattgacg
    67081 aaaacagctc atacatgcaa gaaatcatcg ctgaagacat tcaaaaattt ggtattatcc
    67141 ctgagttgat tggacgcttg cctgtttttg cggctcttga gcaattgacc gttgatgact
    67201 tggttcgcat cttgaaagag ccaagaaatg ccttggtgaa acaataccaa accttgcttt
    67261 cttatgatga tgttgagttg gaatttgacg acgaagccct tcaagagatt gctaataaag
    67321 caatcgaacg gaagacaggg gcgcgtggac ttcgctccat catcgaagaa accatgctag
    67381 atgtcatgtt tgaggtgccg agtcaggaaa atgtgaaatt ggttcgcatc actaaagaaa
    67441 ctgtcgatgg aacggataaa ccgatcctag aaacagccta gaggtgacta tggaacttaa
    67501 tacacacaat gctgaaatct tgctcagtgc agctaataag tcccactatc cgcaggatga
    67561 actgccagag attgccctag cagggcgttc aaatgttggt aaatccagct ttatcaacac
    67621 tatgttgaac cgtaagaatc tcgcccgtac atcaggaaaa cctggtaaaa cccagctcct
    67681 gaactttttt aacattgatg acaagatgcg ctttgtggat gtgcctggtt atggctatgc
    67741 tcgtgtttct aaaaaggaac gtgaaaagtg ggggtgcatg attgaggagt acttaacgac
    67801 tcgggaaaat ctccgtgcgg ttgtcagtct agttgacctt cgtcatgacc cgtcagcaga
    67861 tgatgtgcag atgtacgaat ttctcaagta ttatgagatt ccagtcatca ttgtggcgac
    67921 caaggcggac aagattcctc gtggtaaatg gaacaagcat gaatcagcaa tcaaaaagaa
    67981 attaaacttt gacccaagtg acgatttcat cctcttttca tctgtcagca aggcagggat
    68041 ggatgaggct tgggatgcaa tcttagaaaa attgtgagga aaagaaaatg gcaaaaacaa
    68101 ttcatacaga taaggcccca aaggctatcg gaccctatgt tcaaggaaaa atcgttggca
    68161 accttttgtt tgctagcggt caagttcccc tatcccctga aactggggaa attgtaggag
    68221 agaatatcca agaacagaca gagcaagtct tgaaaaacat cggtgctatt ttggcagaag
    68281 caggaacaga ctttgaccat gttgtcaaaa caacttgctt cttgagcgat atgaacgact
    68341 ttgttccttt taatgaggtt taccaaacgg ccttcaaaga ggaattccca gctcgttcag
    68401 ctgtggaggt agctcgtctt cctcgtgatg taaaagtcga aattgaagtc atcgcagaga
    68461 ttggataagc tagttgaagt ttggtgttgc caaacttctt ttgatataag gagaaaaaga
    68521 tgacaaagaa acaacttcac ttggtgattg tgacagggat gagtggcgca gggaaaactg
    68581 tagccattca gtccttcgag gatctaggtt atttcaccat tgataatatg ccgccagctc
    68641 tcttgcctaa gtttttgcag ctggttgaaa ttaaggaaga caatcctaag ttggccttgg
    68701 tagtggatat gcgtagccgt tctttctttt cagagattca agctgttttg gatgagttgg
    68761 aaaatcaaga tggtttggat ttcaaaatcc tctttttgga tgcggctgat aaggaattgg
    68821 tcgctcgtta caaggaaacc agacggagtc acccactagc agcagacggt cgtattttag
    68881 atggaatcaa gttggaacgt gaactcttgg cacctttgaa aaatatgagc caaaatgtgg
    68941 tggatacgac tgaactcact ccacgtgagc tgcgcaaaac ccttgcagag cagttttcag
    69001 accaagaaca agcccagtct ttccgtatcg aagtcatgtc tttcggattt aagtatggaa
    69061 tcccgattga tgcggacttg gtctttgatg tccgtttctt gccaaatccc tattatctac
    69121 cagaactgag aaaccaaacg ggtgtggatg aacctgttta tgattatgtc atgaaccatc
    69181 ctgagtcaga agacttttat caacatttat tggccttgat tgagccgatt ctgccaagtt
    69241 accaaaagga aggtaagtcc gttttgacca ttgccatggg atgtacgggt ggacaacacc
    69301 gtagtgtggc atttgctaaa cgcttggcgc aggacttatc caagaattgg tctgttaatg
    69361 aagggcatcg cgacaaagac cgcagaaagg aaacggtaaa ccgttcatga gaaaaccaaa
    69421 gataacggtg attggtggag ggactggaat tcccgtcatt ctaaaaagtc tgcgggaaaa
    69481 agatgtggaa atcgcagcta tcgtgacggt ggcagatgat ggtggttctt caggtgaact
    69541 ccgaaaaaat atgcaacagt tgacaccgcc aggtgatctt cgtaatgtcc ttgtggccat
    69601 gtcggatatg cctaagtttt atgagaaggt ctttcagtat cggttctctg aggatgccgg
    69661 agcctttgct ggccatccat tgggaaatct catcattgct ggcttgtcag aaatgcaggg
    69721 ttcaacctat aatgccatgc agttattgag caaatttttc catacaacag ggaaaattca
    69781 tccttccagt gaccatcctt tgacccttca tgcagtcttt caggatggga cagaagtggc
    69841 tggagagagt catattgtag accatcgagg cataattgac aatgtctatg tgaccaatgc
    69901 cctaaacgat gatacgcctc tggccagccg tcgagtagtg cagaccatcc ttgaaagtga
    69961 catgattgtc ctagggccag gttccctctt tacctctatt ttgcccaata tcgtgattaa
    70021 ggaaattggg cgggctcttt tggaaaccaa ggcagaaatt gcctatgtct gcaatatcat
    70081 gacccaacgt ggggagacgg aacactttac agatagcgac cacgtggaag tcttgcatcg
    70141 tcaccttggt cgccctttta tcgacactgt cttggtgaat attgaaaaag tgcctcagga
    70201 atacatgaat tccaaccgtt ttgatgaata cttagtgcaa gtggaacacg attttgtagg
    70261 tctttgtaag caagtttcgc gcgtgatttc atctaacttc cttcgtctgg aaaatggcgg
    70321 tgccttccac gatggagatt tgattgtgga cgagttgatg cgcattatac aggtgaaaaa
    70381 atgagtttca cagtagcagt aaaagaagaa atcctgggcc aacaccatct gagctggcat
    70441 gaattatctg ccattatcaa aatgtctggt agcatcggtc tctcgacttc gggcttgact
    70501 ttgtcagttg tgacagaaaa tgccaaactg gcccgtcacc tctatgagtc ctttctccat
    70561 ttctatgaaa tcaaatctga aattcgtcac caccaacgga gcaatcttcg caagaatcgc
    70621 gtctataccg tttttacaga tgaaaaggtg caggatttgt taagtgattt gcacttggca
    70681 gactctttct ttggcctgga aacaggtatt gatgaggcga ttttatcgga tgaggaagca
    70741 ggtcgtgcct atctctgtgg cgctttcttg gcaaatggga gcattcgtga ccctgagtca
    70801 ggcaagtacc agttggaaat cagttctgtt tatctggacc acgcgcaagg aattgcctcc
    70861 cttctccaac agtttttact ggatgccaag gtgcttgagc gcaagaaggg ggctgtgacc
    70921 tatctccagc gagcagaaga cattatggac ttcttgatag taatcggagc catgcaggca
    70981 cgtgatgatt ttgagcgggt taagattttg cgagaaaccc gtaacgacct caatcgggct
    71041 aataatgccg agacagctaa tatcgctcgg acagtttctg ccagcatgaa gaccattaac
    71101 aatatcagta aaatcaaaga tatcatgggc ttagaaaatt tgccagtaga tttgcaggaa
    71161 gtggcgcaac tgaggattca gcacccagac tactctatcc agcagttagc agatagtctc
    71221 agcacccctc tgaccaaaag tggtgtcaat cacagactca gaaaaatcaa taagatagcc
    71281 gatgaattat aacgatataa agcaacccct tgaattatca atatcttcaa ggggttttgt
    71341 tgtgttatga aatcaaaaag aggcaaccaa ggggcagaat taaaaaatag tatctaattt
    71401 attgaccagt ttatcctcca tatcctcagt agtatgagaa tagatttcca aagtcatttt
    71461 tgcatttgag tgcccaactc gatccattat tgattttatt gggaggccag actctgctaa
    71521 aaacgaaata tgagaatgcc taaaaatatg gctagataag tttttttcta ttttggcctg
    71581 ttttccatat ttttttaata tctgtatgaa gcaagctatt gttgtaggtt gattccattt
    71641 ttcaaaacag aaaatataat catcgcttga caatggctgg aaacgttcgc taagtcgtac
    71701 tatttgtctt tgaatagctt ctatgacact ctctgatact ttgattgtcc gtattgaatt
    71761 tgtagtcttt ggtagcgtct tgattttgtt tactgaatca aaattacctg tgatctcaat
    71821 tttgttgttt tcgaagtcta tattcttcag ttgtaaggca gttaactcac catatctcat
    71881 accagttaat gtcagcacaa gaaccatatc agcgtacttt tggtgatatt ctcgacgatt
    71941 aaggacatcg acaagtgctt ttatttcttg catggtgaga aagttgttac gctttttttc
    72001 cagttcttct aaagtctttg gtttttgagg aattgtagta taatcgacct cgttgttttc
    72061 aatgtaagag tattgaacag cgtaattaaa gatacctctg agcctatgcc gtactttttt
    72121 agctgtaata tatccgttgc tttcaataat tttttcaata gcctcttgaa gaaaacgcct
    72181 gtcaagatta gcaagtatgg tatcggattg tatgacttcc ttcatcttct tatcaactga
    72241 tttacaatta tgttttgttg attcctttac tgtttgcgcc catgatttat agaaaaggtt
    72301 atagatttct tcaaatgtaa tgctttctac ttgttttgtg ctgagttttt tatttatctt
    72361 ctcttgtaac aagatagcag cttgatttct tgcctgggga gttttcttct ccatggttac
    72421 tgaaactttt tttaatttct cagtatatgg atctttatat cgctcaaaat atttaaattt
    72481 gccatttggc aattcttcca tccacattgc gtttacctca cttttttgtt aaaatgggta
    72541 caagaaaact acctttttaa tggttgtttc ctatacatga tttcctcaca ctctccttgg
    72601 ccaaaatttg agtgtgggga ttttttggtt gctatctcgt cagataataa aataaggtgt
    72661 acctcttaga agtacaccag acgattttat ccttgacgaa caaggctttt ttacattctt
    72721 agtgtatttc tttttttaat ttctgtcaag cagttatttc ctaaatggaa atagttggtt
    72781 ttaatttata cttttggttc attacggtgc caatcactag gaaaacctaa agactggttg
    72841 attacattga tgtctataga aggcagcttt ttctctagtt tgataacttt ttttctaaga
    72901 gtattccaca aaatgttgaa tgctgcttta ctaataaagc attgaaggct aataattgtt
    72961 gaatatacag tttttctact gtcatctccc atcaagatct ctttgttatg aatcgtttcc
    73021 caaaacgtac tattagaacg gcatctgaag tttaataagc gattattgtg agcgcatttg
    73081 tttcgtacct cgttaatatt ttttagaaaa gatatcaagg tttctggtgg gaaaacatcg
    73141 ttaaagtcag gtatgtttgt gcttataaaa cttactaaat cccgtgcgat ttcattttgg
    73201 agtgaattag gcaggttttc aataatcgtg cgtaaatctc caaactctag ataatcagtt
    73261 agtacccaga ttgggacatc tgaatgagta tgtgcgtagt ggtgaattga atttcctctg
    73321 tatcgcttgt ttgtgtttat gattttggat agttttgata caataaatcc cacgtctaat
    73381 attttattat ctgcataaga attggtgttt aaataagcgt atttttgact ggggtaagct
    73441 tcggcgaatc tgtgagcagt gattgacttg atatggtgtt cagcttcaag aatagcttgc
    73501 aaaatggctc gttttacatc tttgtcaaat gtatagagac ttgaaacttc gtcaaatgtg
    73561 acgccgtcaa tataagtgtc agtaccaggg tgttgaaaaa acttactgta tccattgata
    73621 atattgtagt aattgttact tagcaggtac ttagctgctt tagattcatc tgtaatggat
    73681 aaccctctga tttttagtgt tgcgatttgt tcctcgattg ttttaaatgg cttcaaaaaa
    73741 actcccccat tctaatttag aatgaaggag tttccccgta tcggtccccg tagagatccc
    73801 gacgcttttt ctctaatgaa ttcattctaa atgatttttt taaaaaagtc aactgttttt
    73861 taatattttt aaaaaataat ttttttattc ccctctatac accccgacta ctgcataaat
    73921 cttgatgtgt gtgtcttcgg ctggtgggaa gtctaggatg atgtcttcgt acttgtcatt
    73981 gagtgacact aggcgtaagc gtccgttttc ggtatatatc ttcttgaagt aagaacggtc
    74041 tccatatgcg ataactgcta aatctccgtt gtaggtagtc agtcctttgt ctactaaata
    74101 gagaatgtct ccgtcttggt agtcgggttg catggagtct ccactgacct tggtcgcaat
    74161 atcgtggcgt ggtggtcgct cgtcaacctc tatagtctct ctgtctgtat cgtcgtaccc
    74221 aaatccatag ttaaatccag aagctgctgc cgtctcagat acaacctcaa cttggtacaa
    74281 gctgataact tccgatactt cgtttatctt cgtttcttct tcgttttggc tctccagaag
    74341 ctcctcagag gtccgtagca cgattttttg attgggtggg gttaattgca ctaccttatc
    74401 cattatctgc tgtgtgagcg aatctggagc gtctggcagt gagttggtgg attcttcttt
    74461 aaaagtagta tctatatctg attttttaac accgaaataa tcagccagtt tttggataac
    74521 accaaaagaa ggagcgcttc ttaacttcat atagtctgtc atagtacttg ctgtaattcc
    74581 aacttcttta gccaactctt tttgggtgat gccacgttgc tttctaaagt gtgtaatatt
    74641 ttcagcaata atttgcattc gttttttttc gtccatttac gattacctcg tattttttat
    74701 aattacatta tatatcattt ttgaatgata aacaatcaaa aatacgaaaa aatcctattt
    74761 ttttgataaa aactattgac aatacgaaaa aatcgtatta taattaaatc aagcttaagg
    74821 aaaaggaggt aaggcaaatg aacgaactag aaagaacagc cctcaatgag atattgagga
    74881 ctgtgacata tatagctgag aagttggatg aagtagattc taagatttct ttgaacgatt
    74941 cacaagctct tgagcatcaa ggaaattgag tttcatttcc atgtagtgaa taactccgtg
    75001 taggtagttc tttaggtctg taaaaccttt atcaggatta tttctatagt aatgaccttc
    75061 gtcgttaccg atataagcag atgcaagcgc aaatgtttta aggtcttcat ccttgatata
    75121 tttttcaata acttgtttta atgacatttt aatgatttta tcttcatcat caggatttgt
    75181 aacaatggag aaatctttaa caaagaactc aagcgcctta cggtatccaa tacctgcaat
    75241 gtggtctagt tgttcgtgtt cagctttcag tgcttggaca tagatttgct taccaattgg
    75301 agaaactatc tctacatcgt cagatatagg tatatcgctc ggaagattag ggattacttt
    75361 gatatgttca atttcgtatt tttcggtata gtcattgatt aaaaatcttg tagctataaa
    75421 ctcctctgtc caaaagtgct tacaacctaa gcatctacat gttaatacta agcttgtttt
    75481 attttctcca agagaaaaat aagaagagtt cacaagatct ggattggttg gttttttaca
    75541 atttgggcaa atgtcttcaa cggttacagg cctagaaaca gaagaattta ctttcactcg
    75601 aaatatcata agatttctcc aatcgtttta ttttgattat accatatttg aaagggggtg
    75661 aggaaatgag accaagacga tatccgtata gtgggaaaaa agagtccacc ttcgtaaagg
    75721 cagaccctga gttaatgttg aatatcaata agattgatgt tggaaatata caagcgaaaa
    75781 atatatttgg aaaaatttaa ggagtaggag gatggatgaa agaaaatata gaacatcttc
    75841 atgaacgcat aaagcatttt cagtcattga ttgcttatat gtctgagcat gagaaaaagt
    75901 attatttaga aaaagattgg ttcgataacc caaccctaat ttctatagaa gacgcaaaaa
    75961 aaagaagtag aactacttta acagaaagga ggtaggaacg tgcagtggac tttagaagct
    76021 atgagaatca acaaaggact tactcaagca gagttggcag aaaaatttga agtttcaagt
    76081 caaacaattg ctagattaga aaaagatagc tctgatatcg gttatcagct attgaaaaaa
    76141 tacatgtttt ttttcaatgt gaaattcgat gatatttttt tagggaaaaa atacgaaaat
    76201 ttcgtaaata actagaaaca aaaaaataag aaggaggaac acatagatgg aaagcgttct
    76261 tgaaagcttg aaacaagaaa aagaccacct cgaaaaaatc attaaggtag ttacctctgg
    76321 tggtaaattt ctgagattgc cgtatcaaaa aaagtcacgc tcgattagtg agaatctgaa
    76381 attgatttct caaaatcttg ataaattgag cgagcaagtt caacaaacca cgaatcagca
    76441 ttcatgattt caagatgacg aaagaaacct gttttgattt ccagtttgat atcatgttac
    76501 agcgactcga taaagcgatt agtgattaaa tttttgagat gtaagttttt ttcatgtcaa
    76561 actttttcat gtcaaatttt ttacactaat aaatattaac taacaacaag tattaaaaga
    76621 caaccagtcc tacttctcta aataaaagag agggtagaaa aaataaatac aaaggaggtg
    76681 aggaaatgag accaagacga tatccgtata gtgggaaaaa agagtccacc tttgtaaagg
    76741 cagaccctga gttagttgaa aaacttttaa gaaacactag ttttcttgag cgtttacaaa
    76801 aaaagcctat caattttcag atagactcag aagaatttaa gcgtcttagc tatgaagcca
    76861 ttcatgatac ttctcaagta actcaatagt agttattaca gaagtcaaac cactgacctt
    76921 ccccagttgc aatccgtctg tatggtcaat ctgtttagta gcttcattag ctttagcaga
    76981 gatagcttgc atatcttcag ctgttaaaga ttctcgaaaa tctttaaagg atttcataaa
    77041 aactcctcct ttctattgga attttgacta aaacggtgag aggtcctagt cgagattatt
    77101 atagcaattt aggaggatat tacatcggtc ttgaggctga tttttggagg caatattgga
    77161 agataaaatc atagaacttg ctgattactt catcagcgaa tctacaacgt acagagaagc
    77221 aaaaatagcg tgtgagaagc tattgaaaca agtcagccac gagatagaac tcagggcgat
    77281 ggaaagtagg acagtctaga agacaacaaa aagcacctga cggaaatcag gcgcatactt
    77341 aaatattcaa catgattata acacgaaagg agcaaaaatg gaagtagttg aaattgtaag
    77401 aattaaagat gtgattattg aaaaagtctc tgctaatgat gaagagttaa aacgtatctt
    77461 tggatgttca aaacgacaag caggagagcg aagaagagaa atgcaaaaac tccctagtca
    77521 gcaaaaacat cttttggata gtggacaact tgtaacgatt aaaggtttct atgaatactt
    77581 gcaatatcgt ggaactaaag cttggaaaaa agaaatggaa acaagcaaga aaatgaggtc
    77641 agcaggatga acctactatc aagaatcaaa aactattttt cggaagaggt caaagaaact
    77701 aatctcgact ggaaagaggt cgctttagac ctcaatcaat cactaattga aacacaggaa
    77761 aaacttcaag aagcgaatca agaaatcgca gacttgaaga aaatcgtagc aatctacaaa
    77821 gaaaaggaga aagaaaaatg atggaataca tttacctggt aataatcgta ggaattggac
    77881 tatggtcgct agtaaataaa ctagatgacc acgctgaaat gaaacaaaaa gagcgccagc
    77941 tgatggcaaa caatgtcgca cggatgaatc tgagaaattc agataagcaa tttacttatg
    78001 atgtagaacc gcctgaaggg ttgaaataag gaggagaaac atgactcaag cggaacaaat
    78061 tagggaatat tatagagagc accctgctgc ctcatgtgat gaagtggctg aggttgtcgg
    78121 tacaacaaaa agcaacgtaa gtgcaaacct ggccaaagac atcaaggcag gcagatgcgt
    78181 tcgcttggaa gacaagtcat acgactactc cccttacttt aatcacacac aagcgctcac
    78241 tgagttggtt gattggaaga atgataccag acgtgagtgg gtggatatgc tgacaagagc
    78301 agcagagaaa gaaacggata gcaacgttat gcgtttgtta atcaaagaag caaataaatt
    78361 gatgaaagag gtgactaagt agatggtacg aaataaaata ggtgatttaa ctaacacgct
    78421 cttcgctcaa ttagagactc tggatgatag ggatcttaca gcagatgaat taaaagtaga
    78481 attacagcgc tcgaaacaaa tggtcgcaat ctcaggtcaa atcttacaag caggtcaatt
    78541 ggcgctagat gctgaaaaat tcaaagacaa ggtaggtgaa gtcaatgccc cgatcgcttt
    78601 gctggaagga tgagtacacg gagtacatgc atgaaatatg ccctggtcgt ttaactcctg
    78661 aagtaaccag gttgctgaat gaaaaatttg gtacgaatta taacaagagt caaatcggtg
    78721 gcgtacgcaa acgtctaggg ttagcagttg gaaaagtcta tcaaggtcga ttgctgacaa
    78781 aggagcaaca tgattatctt gtattgatcc aaaaaaataa gatttctcgt aatgtcgcaa
    78841 atgaaatgaa ccaaaaattt ggcgtatcgc taactgagaa acagattaag agttatcgga
    78901 gaaataataa tctacatagt gggttgacgg gaagattcga gaaagatcag actcctcaca
    78961 ataaggggaa gaagtacccc aatatgccaa aaaacagcgg gcagttcaaa aaaggtaatc
    79021 gacctccgaa ttatgtacct gtcggcacta tcaactacac aacagacggt tatccaaaag
    79081 aaaagattgg agaacctaat caatgggttt tgaaacatcg taaagtctgg gaggaccatc
    79141 acgggctgat accaaaaggg tactcaatcg tttttctgga cggtgataaa acaaactatg
    79201 atatttcaaa tctggcatgt ttatctaaga acgaaattgc tagaatgaat caaaatcatt
    79261 tattcacgtc caacgctgat ttgactaaat caggtattgg actaacaaaa cttacaaata
    79321 aaatcagaga ggtagaaaaa aatggctagt ttatacgaac taacaggtca gttcctgaca
    79381 atttaccaat tggatatcga tgacgaaaca aaagcagaca cgcttgaggc catcgattgg
    79441 caagaacaat ttgaacagaa agcagaagga tatgcccatg ttatcaagaa tctagaagcc
    79501 gacgtggcca tgtacaaagc tgaggaagag agcttcaaag ccaagaaaca agcggcacag
    79561 aaaaagctgg attatgtcaa ggataacatt atggcagcta tgaatgtcac ggggcaaacc
    79621 gaagttaaga gtggtgccct gattataaaa attgctaaga atccagaatc agtcaaggtc
    79681 aacgaagacg accttccgaa aaaatatttt acaaaaaaag tgacgcttgc gccggacaaa
    79741 aaaacactca aagagttgct taaatctggc aagaaagtca aaggtgcgga gcttgtccgg
    79801 acagaaaagt tggtgattaa gtaatggaat tgatgaataa aacacgagta acagattcac
    79861 tagcagttgt gattggacca gaatcgattg aagtacttgt tactgaaggt tttctatttg
    79921 atgttgcgat tcgttttgta aaagtagacg aaacaaatct tgatcaagga aatgaaaagc
    79981 cagtattcac tccggaatac aagctggtca cagttgctaa atacaaggaa aaacctatct
    80041 ttgaatcgga ggaagatatt cgaaaatttg agaagcaagc aaaagaagtt aaatcgctat
    80101 ttgcctttgc aaaggtaaat aaacaaaatt ggtttaacac tgccctttat ccaggagtgc
    80161 tgactgagaa agttggtgtt tgatgaaaat tttagctatt gatccaagca gtaataaaat
    80221 tgaaaccagc acaacaggag ttgtcttgtt ggataatgca agattagttg atagctgggt
    80281 tgtctcttat ggtatgagag gtttcgctga ttggtttcac gaaatcggaa caaatcttga
    80341 attcgatgta gttattgttg aagaatttaa ggcgagggat aacgaaaagt caaaagataa
    80401 tagcgtggca gaaaccatcg cttatatcca gctttgttat ccagaggcta ttcttcaatt
    80461 taatgcaggt tacaagtcgg atattccaaa cgatcttttg aaaatcttag acctttggaa
    80521 atttgaaaaa agtcatcatc aagatattag agcagcagca agacttggat tattttgggc
    80581 aatgagaaat gatattgaag aagtggttca tgatatcgga aaggtggtga gtgagtatca
    80641 caataacgct aagaaagtgg caagctgaag cgattaaaag aagtgaacat ttatctaatg
    80701 gaatcttttt agaggctctt gggggcagag gcaaaactat ctgtgcactt gctattgcaa
    80761 aacataaaaa agctaaaaaa atcatcatca caaacaatcg actagctatt ctgaatggtt
    80821 ggatagatgc agtcaagttt atgaattttg ataaaggtgt tgagattatc attcagacag
    80881 atagatatct tcaaaatcaa gtcaaaaagg ggcataaatt agattgtgat gtgctgatag
    80941 tagacgaatg gcagaatatg tcttctgaca aacaagtggc cttatatcgc aaaataaagc
    81001 gaaaatacac gataggtctt tcagcgacac caattcggaa aaaaggacaa aatttctatc
    81061 cgcttgaaaa aacggtattt ggttgggcaa ccccaaataa taaatttgac tggcaaaaga
    81121 ctcatggaaa aatggtctat gatccattta gctattcaaa agagaagtgg gaagattttc
    81181 aaaattatga aagttatatc tcgagcttgc ctaatttctt ccgctgggaa gagattgaag
    81241 gaattgagaa tgcagttgag aataacggtt ttgagattaa gttttaccaa aagagagtcg
    81301 cctctggcaa tccagaaaaa cttgcagaat ttagaaaact aaatcttgta acagtggacg
    81361 gcaaaactgc aatggccaag caatcgtttg gaagaaagac ctttgaacgc taccttaatc
    81421 aaacaggcgt agcagtcgat tttccaaaat taaagccagt aaatgcggat acgccattga
    81481 tgttacaact tgacggttta atcgaacgag caccacacga tatgttgatt gtcagtaaat
    81541 ctaagcagat tgtcaacgtc attagcgagc gccatcctga aattggaatc tggacgggcg
    81601 atattcaaga aggactttat aagaaattcg tggttgctac tagtcaagtg ttaggtgtcg
    81661 gagtagacgg cttgcaacac aaataccaaa ctattgtcgt attggatcca gtagaagaag
    81721 gttctggaga atatgatgat tatcgacaat tgctctggcg cataacagga agtcgtcagc
    81781 agcatgatgt aaatgtaatt gaattttatt ataaagaaag ttaaaaaaaa gaggaaaaca
    81841 aaatgaataa aacaactgaa atgatcgtat ttcgtagccg taaaactgga gaatttctta
    81901 attcttacaa ggacagaagt tctttagcat ttgcagctga cttttgcagc ttggaatatt
    81961 gtttgaagct tcctcgtaaa aaatacgaag acaacaaaaa gacttacaag gctcttgctg
    82021 cagcttttga ctgtgaaatt gtcgcagttg aagcggaata caaattgacc tatccgaatg
    82081 gatcagaagt tgaacctatc aagcgtgacc gttcatcaat tgaggacatg attaaggata
    82141 ttattggagg ggttctctaa tggcatttac acttccagta aataaaccac aagttccagt
    82201 ggatactcca agaaattttt tcatctacgg tgaaaccatg agcggaaagt cttatcttgc
    82261 aaatgaattc ccaaatccaa tcgttttgaa cacagacggg aatgcagaag ctaacactgt
    82321 tccaagcatt cagctgatca atgaaaaaga tgacaaggga cgaattacca attcagtaat
    82381 taagcagctt ggagatatct tgcttgctct ccagacacag aagcactctt atgaaacagt
    82441 cgttattgat gtaattgacg atgttattga aatgattaag attgcagttt gtgatgaatt
    82501 aaccccagtt ggtaaacctc gcttgaaatc cttgtcggaa attccatacg gcaaaggata
    82561 cgacttcttt aaccaagcta tcacagaatt agtcattgac ctcaaagcat tgccaatgaa
    82621 tgttatttac atcagccgtc aggtatctga atatgatgac aatggcaatg ccaccaaaga
    82681 caagccaagc ttgaaagata agtatgtcaa tcttatcaat ggaaactctg atttgatgat
    82741 ccacactgaa aaactcggca acaactacaa ccgtgaggtt gaccgcaagc gtaagaccta
    82801 ttatgcggac caggttgatg acaaggccat cttgaaaatc ttggcaacta tccgtggggc
    82861 tgttgagcct gcaaagggca agctagcccc taaaaaagaa ccagctaaga caactaaacc
    82921 agctaagacc gaaaaaacaa aagaggcacc taagaaagaa gttgactctg atgatgaact
    82981 attttaagaa ataaaggaga atacacatga gcttactaga tatcgcaaaa tcaatcaaaa
    83041 aagagggctt tgacccacgc aaagacagcg ccaacggtcc tgcaccaatc ccagctggta
    83101 cttatccagt agtcctgaag aaagcaacct tcaacgtatc ggacaaaggc tgggaaagcc
    83161 ttggttatca atttgaaatc cgtggcggtg attacagtgg acgctctgaa tttgcaacat
    83221 ttggcacact gactgaatgg aacggtaaga accttgactg ggcagttgaa cgcactatga
    83281 aattctttat caaagccttg gtccttgctg gcgacagtat gcaaggaaat gaagaagacg
    83341 gtaaagcctt ggaagaggct ctaaaacgta aggcagttgg ctcttactac aaccttgtta
    83401 tctctgtgac taaggggaaa gatggccgtg agttccgaaa ctatgacctt gaagaagaag
    83461 aagcacaacc gctgactgaa gctgatattg atgacgatga cctccctttt taagaaataa
    83521 caagttctgg gtcattgatg aaactgatga ggaatttggt cctttcacga cagtagaaga
    83581 ggcttataca gctatgctaa catacttgga tatgactgaa gccgaatatc agtcaaacta
    83641 tacggcccag gaacttgttt atatttacaa agaggagaaa aaaccatgcc gtcgatgaaa
    83701 gaatacgcat tacagtacca aaagttaggg ttctcagtca ttccaatcaa tcctaaaaac
    83761 aagatgcctt tgattgattt tgctgataag ccagccatga ctccatctga gattgaaaac
    83821 ttttgggacg gctaccctaa tgcaaacatt gccctaaaga ctaccaactt ctttgtcatt
    83881 gatattgaca aacacggcaa atcgaacggt tttgaatcgc taaaaaaatg gaaacatcta
    83941 aatttaatcg aaccgacact gcaagctaag acggctagtg gcggtaaaca tctattctac
    84001 ttcaaacgag aagatgagcc gatcactcag atgattggat tcttgcctgg tgttgatatt
    84061 aaggctcacg aaaataatta tgtgttagtc gcaccctctg ccacagataa agggcagtat
    84121 gagtgggatc tggaaaagtc taaggaaggt ggcacgatgg tcactccttc aaaagattta
    84181 atccagtcta taaaaaaaca gtatggcgaa actcacggtt ataagtatga tggtaaggac
    84241 ggtcttaggg atttagttag acgttcacat actagagacc gaacacagac tacagatctc
    84301 tttgaaacca tcgcccttgg ttttggtgat gaaggtggac gaaatgacaa actagcaaaa
    84361 ttcgtaggtg gtctcttata tcgtgcggtc gacgatggtg tagttgttca acttgcaaga
    84421 ttagcaaatg caaatagtcc aaaccctttg cctgaaaagg aaatgatgcg tactattgaa
    84481 agtatgatta aaaaagatag gaggtgattg tgattggtaa tgtagtaagt attgactcac
    84541 aacctaagat gataacgact gccaagggag acatcaaggc caacagtcca agtaatgtgt
    84601 tgatgtcttt caaagctgat gatcagttga gtatttacct aaagcacaac gatttttccc
    84661 aagagcatga actccttaaa gatatcaaga tcggcaacac tctttttaaa aaaggtgagc
    84721 tcccttctaa ctttgattca gtcgtaaaag tttactttga aagtgtgtta ggtgttgctt
    84781 tctcaaacca agcgatgctt gatggcatgg agactttctt ttcagaaaga tcatacaatc
    84841 cagttattga gtatatggag agagcaactg aaaagtggga cggcagaaac cggattgacc
    84901 gcatgcttca agtatatctc ggcgctgaag atatcccttt agtttctaaa atcgctcaaa
    84961 tgtggctagt tggtgcagtt gctaaagttt atgatccata cgttaagttt gactatgttc
    85021 tggacctggt cggtggacaa ggagttggga aaacgtccct ccttcaaaaa ttgggtggcg
    85081 aatggtatac ggatgccgta acagatttct ctaataaaga taattacgac attatgttaa
    85141 agagtctaat cgtcaacgat gatgaaatgg tggccagtaa tcggatgagc tttgcagaaa
    85201 ctaaggcctt tatttctaaa actagcctac gttatcgtaa accatacatg aaacgaacag
    85261 aagaatttgc caagaacttc atcttagcca ggactactaa tcaaaaagaa tacctcaagg
    85321 acaaaaccgg tgaacgtcga tttctcccga ttatggcaga tagcaagcaa caaaagaaac
    85381 atccaatgga aatcgagcca gagacaattg aacaaatctg gggcgaagcc gttacaatct
    85441 atcgtgctgg tgctgatttg atgtttgatg aaaatacaga ggatgaactg aatatctacc
    85501 gtgaacagtt catgtatcgt gatgaagttg aattacaagt gcttgaatat cttgatatgc
    85561 ccgtccctga aaattggcaa aactggtcta ttcagcaaca acatcaatac acaagtaaat
    85621 atttcgataa tagtagcgac tttgatcctg gaagcaaaaa actagataag gtctcaactc
    85681 gtgaaatgat gtacaactta tttatgagaa attcgaatga caggaagctg tcaacgaaga
    85741 ttaacatgat catggataat catcctgatt ggaaaaaaag tgttttccgg gcaggaggta
    85801 aaagtacaaa agggttcgta agagtgaaag attcggaaaa aactaatcgg tagcaattaa
    85861 aaaattatcg gtagtcatcg gtagcagttg agggggagat cggtagcatt ctaccgataa
    85921 aataggacat cggtagcaca tcggtagcag tctaacccct tgatattact gacttttatt
    85981 taatatttat atataatgct actcttctac ctatattttt aaaaaaagta tataaaataa
    86041 tagtaataat aaagaaagcc tatagaatag ggattcttga aaaaaacttt ttacttttta
    86101 gaatttatcg gtagcacggt agcagtttag aaaaaagagg taaaaatgtc atacacagta
    86161 acattatttt ttgacaacat ggtagacgaa actcactttt ttaagaaaga gagtgatgct
    86221 gccaaatgca aggctcagtt agaaagcaag tatcgaggga atcgaatgta taaagttaag
    86281 caggagaaat tggaagaatg aataagcagg aactgattaa acgtatcgag gatttgcctt
    86341 atacagaggg gcctatcgca gatacaatcg aaattaatag aaattggata ttgaaatcaa
    86401 ttgaacagct agccgaatcc gaaataggtc acgcagatga agctccacgc tacgtaaaga
    86461 acatactagc acgattgcga gaattgccat tgcatgatag agaggtttgg ttaaaggcta
    86521 tcatgagcga atttgaacag gattttagcc atgcaaaatg gcgagagggc tacgagcaag
    86581 gtaaaattga gggtatggtt gaacgtgaaa aagtcatagt tccgcagtgt gtggcggaat
    86641 atatagaatt taaaaagaaa aacaattttc atgtttacgg tgcaatgaga gtaattgaag
    86701 atcattatga taagaaagtt cctgattggt tttacgaaaa taacatcgaa aaattctgtc
    86761 ttgcttggct tgacggctac gaggttgaaa aagagaagcg gtattttgtt aagattaaag
    86821 ggaatattaa agaaaatatg ttggtttatg gagaactttt gaaaaggtat ttctttacaa
    86881 aaagctttag tttagacgat gttatatatt cccacacccg taaagaacta gaaaatgcaa
    86941 aaatcggctg ggtgtttgat tgtgaagggt ttgagattga ggaggtggag tgatgagcct
    87001 tacgctaaat agcacaattg gagacttagt tttggcaatc ggagaaatta tcgttggttc
    87061 tgatggtaaa accactacag cgatactgga gatacctgat caaagctttt acttagagat
    87121 tgagcttaaa ttgaaggagg aggtcataaa ttgaaacgat tcatagctat ctggattctg
    87181 ctatctgctg gattgaatat ctggcagagt atctacatta aaaagttaga agaaaagcgc
    87241 cctattgtcg tctataaagc tgataacgca ggcgctgaga tattcggtaa agtcgtcgag
    87301 aaaggacggc atggcaagct atacacgctt accattcgtg actacggggt gttcgtggtt
    87361 acgaaggacg tgtatgagaa agtgaaagta ggggatgagg tgttactcta atggatgata
    87421 ttttacaagc tttagcaaaa atgctaaata tgactgttga tgaagtaagt tctttgctta
    87481 caacatttaa agggaatgca ccacagattt atgaaatgtt cgttaaagaa aagatgtttt
    87541 atgatctctt cagtcttttt caaatcatgt caattgtaat atttagtatt tctgcagtag
    87601 ttttagcagt tttaactctc atatatttta catacgatgg tggttttgtt tattcctatg
    87661 atatacgtac aggaaaaacc gaggaagaaa ttaaattaga acgcattgaa cggaaaagaa
    87721 aggacttaaa aataccacta aaaattagtt gcatttcatc aagcgcaagt ttgataacat
    87781 tagttattgc aattgtttta aaagcaactc ttgcacctaa ttatatattc atcgtgaatg
    87841 agattttacc aaaattaacg aagagatagg agttatcatg aacgcactag aaaaagtcga
    87901 acaatggttt atcgaccgtg aaatcaaaga ccgaaaaggt cgctggattg atggctcgtt
    87961 tgtcaaagag gaggatttgg catgataccg aaatttagag tgtgggtaaa aataggaaaa
    88021 cgtatggttt tttcagatga cattcttgct attgactacg aaaacaaaga aatagtgaca
    88081 caacaagttt attttgagaa tggtttacca gacgatagag atatctattg ttatgatttt
    88141 gacgaaatcg aactcatgca atcaacagga ctcaaagaca agaacggcaa ggaaatcttt
    88201 gaaggcgata ttgtacgaac tactagattt ttgggtagag ctgacgaaat tggcggtttc
    88261 tatgagtatg acaaggaatt tatagggatt gttaagcagc ttgagggttc ttgggtaatt
    88321 gatacgggca gtgacgcagt atgtttatgg actgaaattg aagaaaatga aatcatcggc
    88381 aacatctatg aaaataagga gtttggagga cgcaaatgag accttgtaaa tatccatatt
    88441 caggaagaag aaaaaaacaa gaaacgccgt cgccaatatt ttctgcacga ccaatttttg
    88501 acgaagttcc aattgtagaa gaagttaagg ttgagttcgg agttgaagct agtatggggc
    88561 gcatatatcc agaaacgtta atacatttag atatttctgg atacggaaat agagtgcatt
    88621 cagtacatcg cttccccggt attttactga gtgttggtga gtcaatccaa ctaaagatgc
    88681 ttttctataa aagacttaga aattttacta cagatcgttt cttgacgttt agagaatctg
    88741 attggaagtt ctttatccgg gacctggtca acgaatttgt gcgataaaaa agccaagaca
    88801 ctctctgtct cggctaaatt cctaataaga ctattatatc acaaaggaga cagagagtga
    88861 acaaggctaa agaactattg aaagagttgc agaatctgga catggacatt caaagccgta
    88921 tagatgaaat taacgagctt gaggcaggtt tgctctcaag ccccaagtgg attgacgtca
    88981 aagtccaagg tggtcaagct agaaaagttg atgatgtcta tactcagctt gtcgtgatga
    89041 aagaggccat agaacaggat actaaagagg ttatcaacag aaagcttgag cttggtaggt
    89101 tgattaacaa gctgaaaaat ccaaagagca ggtctattct cagggtgact tacattacta
    89161 agatgtatgt tgatgatatt tgtgacaaaa tggaaatcag cagaacaact ttctacactt
    89221 ggcggaatat ggctatctct gaactgaatg aggttttgga gagaatggaa ctaaattgaa
    89281 ctttacaaaa ccgtacggga aaaaatgata cttgttagca cagttttgta attctgataa
    89341 aatggtagta tcaagaattg aaaagagagg tctcagaatt ggtagatggt tacctgtaat
    89401 gtcagggggc tgtaatggcc ttggaggttc aagtcctccc ctctcctttg agtgtttgtg
    89461 tcccagaatg agttaaatct tctgggtggg gattcacata tcactcatta acttaaaaat
    89521 ggttgcggaa gcgactggac ctcgcatgat tgcgtagcta attatattcc ggataagtta
    89581 taagctagag ggtttgattc cctcagaggt tttaaagact acaaaaaata aaaaagaagt
    89641 caaaatttaa tacgcacgca aggtagtagt cgccttgcaa gaaggtcgca catcgtgtgg
    89701 ctttttttga ttattcgaag ggtggtgatg gaaaattgag tggattgaga ataaaacaaa
    89761 agagatttgc agatgagtac atcatctcag gtaatgcgac ggaagcctat aagaaagcag
    89821 gttatcgtgt ttctagtgat agagtggcag gcgttgaagg acataagtta ctaaagaatc
    89881 ctaagattaa aagttatata gatgaacggt tgaaacagct tgattctgaa aaaatcgcag
    89941 accagcaaga agtccttagt tatctaacct cggtaatgcg aggagagaca caagaacaga
    90001 ctttgataag catcggagaa ttgggtcaaa cgattacgga tattaatgtt ggagcaaaag
    90061 acagaatcaa ggcagccgaa ctattaggaa aacgtcatag gctttggaca gacaaagtag
    90121 aggcagacgt ttctgggacg gtggtgtttg caaatgagtc agacatacca gattaaacaa
    90181 agtgatattg taatcgacct acctaagaca gtaggagctg gatacggaca gttctggcgc
    90241 tcaagaaatc tttatcgtgt tgtaaaaggt tcccgtggtt cgaagaagtc caagacaacc
    90301 gctttaaact atgttgtccg tcttttgaaa tattcctggg ccaacttgct tgttattcgt
    90361 agatactcga ataccaacaa gcaatcaact tatacggatt ttaaatgggc gtgtaatgtg
    90421 ttgggtgtga ctcatttgtt taaatttaac gagtctttgc ctgaaataac cataaaagcg
    90481 actggtcaaa aaatcctatt ccgtggtttg gatgatgaac tcaaaatcac atctatcacg
    90541 gtcgatgtcg gcagtctttg ttgggcatgg ttcgaggaag catatcaaat tgagactgaa
    90601 gacaagttca gcacggttgt tgagtctatc cgtggtagct tagatgtacc tgatttcttt
    90661 aaacaaatca cagtcacatt taacccgtgg aatgagaggc attggctcaa gcgtgtattc
    90721 ttcgatgaag agacgagacg ggctgacaca ttcgctacta caaccactta caaatgcaat
    90781 gagtggcttg atgaagtcga tatcaaacgc tatgaggatt tgtatcatac gaaccccaga
    90841 cgtgctagaa tcgtttgtga tggtgaatgg ggagttgctg aaggtttaat ctatgagaac
    90901 gtgaccgtca aggatttcga taaggatgaa ttgctacgag attcagctaa taagttatgt
    90961 atcggtcttg actttggttt tactcatgat ccaactgctt tgtgttgttc gttgataaat
    91021 gacacgacga aagagattta tgtctttgat gaggcgtata aagtcggatt gataaccaaa
    91081 gaagttgcga agatgataaa ggacaaaggt tatcatcgct cacaaatcat tgctgatagc
    91141 gcagagtcac ggctgattga agagctcagg tcagaacatg gcatatctag aataaaagag
    91201 agtcggaaag gtaaggatag tattatggca ggcgtatcaa aattgcaagg atacactatt
    91261 tatgtgcatc cagattgtaa aaacatcatg gatgaatttt atagttactg ctaccagcga
    91321 gataaagaag gcaactggtt gaataaacca gaggataaaa acaaccactt gatggacgct
    91381 ttgcgttaca gccttcaatg tatcgaaggt gggaaagcaa ccgtccgcag acgttctgat
    91441 tatggtctat agagaggaaa gacatgtacc aatatttaac ctatccacgg gatggatatg
    91501 atgagggttc tttgaagaaa gacctgattt acaaattgat aacgatacat agcactgaag
    91561 gctcgcattt gaagaagctt aaaagctact atttgggtga gcatgctatc ttaaaacaca
    91621 cgagacgcaa cgtgaacgca cctaattaca agacggtagc caatcatgcc aaggatatcg
    91681 cagacacggc tacgggctat tttatgggca atcctatcaa gtataacaat actgctgacg
    91741 gtgatatcga tgaactactt acagcctttg atggtgctga gattgaccaa gtagatgctc
    91801 agaatgcttt gaacatggct atctatggtc gtgcttacga gtacatctat gctaaagagg
    91861 gtatggctga gttggattca actagtattg atccggagaa tactttcatg gtctacgatg
    91921 atagtattga gcggaagcct ttgtttgcgg tctattacta tgaagtaaaa gacgatacga
    91981 aagacactac caagcaccag gctgaggtct ttaccgaaaa tctgcactat cacatggtgc
    92041 tgagaagtac agattcagga acaactcaga gcgaggaggc aacacctcac aaccttggtc
    92101 aaatcccaat tatcgaatat cgcaacaatc actttgcaat tggtgactat gagcaacaaa
    92161 ttagcttgat agacgcttat aattccttga tggggaatcg tgtcaatgat aaggaacagg
    92221 ctgtagagtc tatccttgtc ttgtatggca cgcagttagc agacactcca gaagacgcta
    92281 aggtagcaat gaagattctt tctgaagaag gtcttttgga attgccgggc gatagtgcaa
    92341 gggctgagtt cttgaagaat acgctggacg aaagtgctac tgaaatcttg cgtacagctc
    92401 ttaaagagga catctacaca tttagccatg tgcctaattt gactgatgag aatttcgcag
    92461 ggaatacatc aggcgtagcc atggaattta agctgatggg ccttgagatg attactaaga
    92521 ccaaggaagc gaactataag cgaggattgc gtcagcgtat tgcgattttt gctcattact
    92581 taggtatgaa gcagattgct ttagagtctc attcaatcgt tccacaattc agtcgtggtt
    92641 tgcctaagaa cttgttagaa atctctcaga ttgtgaacaa cttggaaggc aaagtgacca
    92701 atagacagct tatttctctc ttgccgtttg tggaagaccc tgacgctgag ctggaagcct
    92761 tggaagaaga aaaaaagaag aacatggaag acatgccgat gttcaaccaa gaaaacacga
    92821 aacccgaaga cgaggtagag gatgaagaat caggagtatt gggcgaagag gaaagccaat
    92881 ctgatttacc agcagatgga caaggccgaa aagcaggcag accagttcga taaggtctat
    92941 caggaagcca agacttactt ggataaggaa gtcaataaga tttttgataa gttccaacgt
    93001 gattatggtc taagtcaggt agaagctaga caagtcttga agaacatgaa agacaagaaa
    93061 aatctgaatg aacttcgtaa agtacttgaa gcgagaccga atgacccgaa catccaaaga
    93121 ttactagctg acttagacag cccagcttat tctttccgta tgaagcgcct agagcgtttg
    93181 agcgacgatt tagaccgtat gcgtgaatct atctatcatt cagagaagac aggctcagac
    93241 gccttttata gcgacttgat gaaggatagt tactacaagg ctacctttga cctgcagcag
    93301 cagacaggac tagcatacgg cttttctggg cttcctgaga gcgagattaa acatctacag
    93361 tctttcagtt gggtaggtga cggaagtacc tactcaacaa acatctggaa gaatacgggg
    93421 aagcttactt ctagcataaa agatgaacta cttatgagcc tcatgacagg ccgagataca
    93481 cgagaaactg cacaagcaat tgctgagcgg ttcaatgtgg ggcagaacga tgcaaggcgt
    93541 ttggttcgga cagaatcagc cttttttcat aaccaaatgg agctactcaa ctatgaggaa
    93601 gcggatatag agaagtatat ctttgtggcc gtcttagaca agcgtacatc acgcatttgt
    93661 caggagcatg acaatcaggt ctatgatagg gataaggctg tccctggtgt caattgtccg
    93721 cctatgcacc cttggtgtag gtctactact gtcggatacg atgaggacgc agactacagc
    93781 aagttgaagc gcagagcaag gaatccagag acaggtaaag ttgagtacgt gcctgccgat
    93841 atgacttata aagagtggta tagcaagtat gttgcgaaag atgtaaaaaa tgaaatacaa
    93901 gattataaga aaagtgacaa aaccgtttca agatataata ccccaaaatt gttttctgat
    93961 gttagtaacg catgggatga aattgggagg ggtggattat cgaaagaaca acttgtagac
    94021 ttgctagaat ctgaatatga attaggtaat ttttcgagcg atatagcaaa attgatagga
    94081 gtaagttctg cttatataga tgttagtagt ttagctactt cattagtgag acatggacaa
    94141 cagtattcct tagatgaatt tatgttaata aaagaggcgg ttcaaaaacc ttatttgatt
    94201 ctagataatt cagagagggt tgaaaaatca attatttcat atgtaaaaat acctaacaaa
    94261 gataaggtca ttatggaagc ggtgatggtg ccacgagatg aaatgctagt cattcacttt
    94321 aacaaggtgg ggattcgtca agttaaaaag aatgaaaaaa atatgtcgac gctttacaaa
    94381 aagggaaaat aatgctatac tcttggtaaa gatagaggtt gagaatctgt caccaacgcg
    94441 ccacttatag tgggtcgaga aatgcaggag ccccgacagt cctgcctatc tgtgcactaa
    94501 acaatcgttt agtgcttttt ttgtactcag aaaggattga aaatggacac agcaagaatt
    94561 gggataacta acgtagaatt ttcaggaaca ggcgaaaatg actcagcgac agtgaaatta
    94621 gagttaaata tttatggggc ggatacgttc agcgcgattg agttactacc taaaatatta
    94681 accgacattc attcattatc gtatgaagtt gattgattgt gacattaaaa ggagtgaaaa
    94741 catgtttata tgggattggg tatcaatcgc ctttgggtgg ttggtatttt tgttgttaat
    94801 atttattatt atggccgtaa tcagcggaat aattaaaggt gtaaagaaag gaacagaaaa
    94861 atggaagaat ggaaagaaag atttaaaaaa gaatactacg aattgaaaga acgattccag
    94921 aagttagata tgatgattgg gaaatacgaa aaagggcaac tagagtttga atctaaatgt
    94981 ccgattgatt tgttaaaagg tcagcgttca accatgtgga attatttaag aattctagaa
    95041 caacgtgcaa aaattgaaga aattaaacta taaaaattaa ccgcatcgaa atcgaggcgg
    95101 ttttcttatg ctctaaccgt atggaatccc gtacggtttt tatattgtcc aaactgtacc
    95161 gatgacatta aaagctgtac tgttccgtcg ccggacgtaa agcgagatta tcgagtggcg
    95221 acgtaatcgc tggaggacaa ttatgtcaga agaaatcaat gcaactgtat ctactgaatc
    95281 aactgagact gtcgacactc aaggaaatgt tgattcagtg caggaagaaa agcacgaacg
    95341 aactttcact cgtgctgaaa tcggtaagat gctatctgcc gagcgctcta aatgggaagc
    95401 tgagcaagaa gccaaggaaa acgaagccaa gaaacttgcc aagatgaatg ctgacgagaa
    95461 acagaaatat cagttggatc agcgtgagca agaactagct gaccgtgaga aggctattgc
    95521 tcgcaaggaa ttgaccgcag aagctaaagc aatgctaagt gaacgtgact tacctgttga
    95581 gttagtaaat gtagttgatt tgacaagcgc agagacggta tcgcagtctg tcgctgtatt
    95641 gcagaaatca tgggagcaag ccgtgcaaaa aggcgttcaa gaaaaactaa aaggcggagc
    95701 tccaatgaaa caagcgccag tcgatagtga cggtatcaca aaagaagaat ttgctcgtat
    95761 gggttatcag agtcgaaatg agctctatca aaagaaccca gagctttata agaaattgaa
    95821 aggataatag aaaatgacag caggacaaac taaattagcc actatggtta atccagaagt
    95881 aatggcggat atggtagccg ctaaattacc taaattgatt aaatttacac cgctagcgta
    95941 tgtagagaca aagcttgaag gtcaaccagg tagcacttta acagtgccag catgggagta
    96001 tgcaggagac gctactgaaa ttgaagaagg ccaagcaatt acgccagacc aattgactac
    96061 taaaaagact actatgacca tcaaaaaagc aggtaaaggt tatgaaatta ccgatgagtc
    96121 tcttttgtca ggtcttggtg acccactagg tcaagcgact taccagcttg gtttagctat
    96181 tgccaacaag atcgataatg atttggtagc ggtagctaaa actgcaacac aacatattac
    96241 agaaactcca acaactcttg aggcaatcga taaagctcta gatatctttg aggacgaaga
    96301 agatgcacag tatgttgcta tcatcaaccc taaagatgct actaagctaa aaactgcagt
    96361 agcaaaagaa tggattaaag gttcagagct tggagcaaat atggttgttt ctggaacctt
    96421 cggtgaagtt gatggtgtgc aaatcgtgcg ctctaaaaaa gttgatgaag gtaaaggctt
    96481 ccttgttaaa gtgtcaccaa gtcaaactca gacagacgac gctaacaaat atggagcttt
    96541 tgttatcttg cttaaacgtg atgtggctat cgaaacagac cgcgatatct tgaagaagac
    96601 taccgtaatc acaggtgatg aacactacgg cgtttacctt tacgacccta cacgagttgt
    96661 aaaattcggt ggcgcgtaag aggtgacgat atgagtttat tgctacgacg tcattatatt
    96721 caagaagagc aggttaacca gtattctgat ttagagaata aaactctaga agagttgaag
    96781 gatctagcga aagaagcagg tgtagcaggc gcttataagt tgacaaaagc cgaaattgta
    96841 gaagttttgg aggaactaaa aagtgaaatt taaaatcaaa caagatttct atgattggga
    96901 atcaaatgtg aaacgactgg caggagagga acttgagatt actgaggagc gctatgctga
    96961 gctggctgac aatattgcca gcaacggtgt cgctatctca gatgttcttg aggaaatctt
    97021 tcctaaacct gagttcttag aagaggattg atatgtctat agagttgctg aagaaattaa
    97081 caggcgaaga agatactcag cttctcatgt tgttccaaac aagggctaca aatcttatct
    97141 tgtcagagac taatcgcaca tctttgacac ctgctttaag tcttttaata cctgaggttg
    97201 ctatcgagct ccacaaccgc tcaggagcgg aaggagagcg ttctagaacc gaaggtggta
    97261 tagcagtagt ctacggagaa aatggcctgt ctacgggtct tctacagcga atacgcatgc
    97321 acaggctagc aagggtggca ggtcatgttt ttgaagcaga gtagactgaa accttatcca
    97381 atgcgacggt ttgaaaagac tgtcactgag gaaggtgtcg cgaaagaagg gtatgccaag
    97441 gaagctgaga cagtccgcct tgaattgtgg ccagctagta gcaagctaca atctgaattg
    97501 tatggcgagc gtgtcaatga tattttgaac gcaaatgcca acaagtcagc tactatcaaa
    97561 gtaaaagatg gtgtgtgtat cgatagtcag acggaagtga ctcatagggt tatttctaaa
    97621 aaggtctaca cacatcatca agttttggag ttagagcgtg tcagggctac taggggcaga
    97681 taggcttata gctaaatgta gacgattggc tagtaaaaaa actggcgagg atatcgtctt
    97741 acgtgcggtg cacaatgcta ctataaaggt tgtccaagca gatgcaagaa gactcgcacc
    97801 agcgagagat ggagagctta taactagtat caaaactagg gcaaaaatgg acggagataa
    97861 ggctataggc gaagtttaca ccaaccttaa atacgctcct tatgttgagt ttggaacggg
    97921 accaatagga caagctagcc attctggtat ttctccagag gtcagcgtga cttacaagtc
    97981 tagtccgtgg tatgtacatg aagaccaaat caatgtagga ccgtaccact ttcaaaaaat
    98041 cggggagttc tacaagatgt atggtcaacc tgcccagcct tatctttatc cagctttgag
    98101 agacaatcaa gagcgtgtgt ctaagaatat ttcgaattat gtccgtagaa agataagaga
    98161 acaaataaaa tgattaatat caagcctgtt atttataaag aattgcaaaa ggttgcagat
    98221 aatgtgaccg atacttatcc tagcgattgg gagactttcc cagtcgttat ttttttggaa
    98281 gaacaaaaca agccgggtga ttggtttgac gacaaggaac aaaaatcctc tatccgctac
    98341 aaggtggata tctttgatga tactagcact agtgagttag ctgttaaaat caatcagatt
    98401 tttgagtctt taggtttgcg aagaactgac tgccaagacg tgccagaccc gtctcatttg
    98461 agacataagg tcatgcgttt tgaaggtatc gtcgacttac actcagagct tgtttttcaa
    98521 tttagaatgg agaattaaac atgttagcaa atggaattac gctttcttat ggcgaaacaa
    98581 aagatagcta tactaaactt gttggattga aagaagtacc agagtttggt attgaactcg
    98641 aaaaagtaga aaatactact cttgaagata cggtgaagaa gtacgagttt ggtattgggg
    98701 acataggaga acttgagtac aagttctctt ataataattc aagcgcaact gctccttatc
    98761 gtgtattgcg taaggcagca gacgacaaga agaaactcta ctttgaacaa gcttatccag
    98821 acggtactaa ggtcattttt gaaggccaag tatctgttaa gcttggcggt ggcggtgtca
    98881 atgccgttat cgatttcaca cttaagattg ccttgcagtc taatcttaca tttactgatg
    98941 gtattggagg ttaattaaat ggcgttaaaa tacacaactt ggaaagttac tgacgaaaaa
    99001 gagttgaagc tacgtttgac atctcatcaa gctgcaactg tggaagaaaa aatcggcatg
    99061 aacttgctga agattttcat gcctgaagct ggcgaagagt tcactttacc gcctttgaaa
    99121 gttatgttgt tgttagttca cggagccttg cagcagtatg aacatgggta ttctcttgag
    99181 gatgtctatg atttatacga tgaatacgtg gacaatggcg gagaccaaac aaccttcatg
    99241 acagaggtgt tgatgccact ctttgaagta tcgggtttta ctccacgagg aagcaaggac
    99301 aagaaaactt ccaagaagaa aatgacagta gacaagtaat cttaacggta actcagatta
    99361 ttgagaggct ttatcctatg tttttggaca tcgggggcaa gcctcttgat ttttgggatt
    99421 tgacggtact tgaaatcaga gaaatgattg aaagctataa ccgtgtcaaa atccaagagc
    99481 gtaaagaaaa gattattgac tcatacagac tttcgcagat gatatccaac cacgtttctt
    99541 tattgttatc caaagatgcc aaggcctttg agttctggga atatgcgcct gagttgtttg
    99601 tagaagaaca acaagcagta gaacaggaac gacagaaaca agcacttttg ttgcataagg
    99661 aacggatgcg tgaatttgca gagagacata atcgaaaaag gaaggaggaa gtaaatggca
    99721 actcttgatg aattgaaagt catgattgac gctgagatag cgcctttcag gaagaagatg
    99781 aaagaagtcg agaatcaggt caaaggaaca tctgaccaag tgaaaaatgc tactgccaaa
    99841 gttcgtgaac agtcgagctc aatcggtagt gcgtttggca agctggctaa gttcgctggt
    99901 tttgcaatcc ttggtaagaa attacttgat gttgggatgt attcaacgca gacggctctt
    99961 gaagtatcag cgtctatgaa ccaaatcaag cgacagatgg gcgagagttc gcaatctttc
   100021 ttaaaatggg ttaacgataa tgccaacgct atgaatatgg gtgtgggtga ggctaccaac
   100081 tacggtgcag tctactcaaa cttattttct ggatttatca aagataccaa caagctaagc
   100141 gcctataccg ctaagatgtt gcagacatcg gcagttgttg ctgaaggttc agggcgcacg
   100201 attacagacg ttatggagcg gattcgctca ggtttactag ggaacaccga agcgattgag
   100261 gacctaggaa tcaacgtcaa cgtggctatg attgagtcca ctgaagcctt taagaagttc
   100321 gcaaacggac agagctggca acagttggat taccaaaccc agcaacaaat ccgccttatg
   100381 gctattctgg aacaggctac agccaagtat ggggatacct tgtctaattc tgtaaatggt
   100441 cgtatcagcc tatttaagtc gctgatgaag gacgcagcat tgaaccttgg taactctatg
   100501 ttaccgatta tcaatgccat tatgcctgtc ttgaactctt ttgctatggt cttaaagaac
   100561 gttactgcta aactcgctga gtttatcgct ttgatgttca acaagaaagc aacagtgaaa
   100621 gatggtgttg gtggagcagt tggagacatg ggtaacgcca tgaaggatgt tgcaggcgga
   100681 gcaggagacc ttgctgacgc agtagacgac gctggagatt cagcaggagg acttgctgac
   100741 aatcttggag actccgccaa aaacgctaag aaggccgcta aagagttgct aggtcttttg
   100801 ggatttgatg agattaacat cttgcaaaaa ccaaaagatg acgacgcagg cgggtctgga
   100861 ggcggtggca aaggtggtaa aggaaaggga ggcggtggcg gacctttcaa agacatcttg
   100921 ccagaagtcg agttgaccga catggacaac aaattcaaga gcatttttga tggtcttgga
   100981 gataagctca aagggttgtt tgacctcttc aagaaaggtt ttgatgcagc atttagacca
   101041 gaaggtatag aacgcattaa gactgcctta gaccaaatag ctaagacaat gggagaaatc
   101101 gccactgacc caagggttgt gaatgccttt aaccgaatgg ctgagaaaat tgcttatgct
   101161 ttagggcaag tgacaggctc aataacaact atcgggctag gtatcggtgt tttccttgcc
   101221 gaaagtattg caaatggcct tggaaggcaa aaagaacgca ttaccagggc gctagtcgct
   101281 ttgtttgata atattggtaa catttccgag gcagtaggaa acatcgctca ggacttttct
   101341 agtactttct acgacgtcat tacctcaact ggtgcggttc gtatcggtag cgctattgtg
   101401 tcaactctgt tgagtttgac atctaccatt gttgaagttg gtagtaaatt agcaggaagt
   101461 ttgtttaaag gttttgaaaa agtcgttgtg acaagcactc ctaaaatttc atcagtcttc
   101521 caaagtttat tagatactgt tgcgcctgta tttgagagca ttgaaaggtc tgttaacaaa
   101581 tttggcgatg gcttaagtcg tgtttatgat gaacatgtag tccctgctat taactctatt
   101641 gctaatgctt ttaatgggct aattgacatt attcagattc tctgggagaa ttcctggcaa
   101701 ccttttgctg agtttttatc aggagtattc ggtgttagta ttgaaggaat ttcagattta
   101761 ttaggaggtg gccttttagc cactttggga ctattggcgg atgctattaa gttagtggca
   101821 gatggtttca ccgttttttc tgactggtgt aaagaaaaca aagaacctat cgtagctttg
   101881 ataacaactt ggcaaacgat taatttctta tcatgggcag aacaagctgg aggacttgca
   101941 ggagcattca gcttgttagg tagtaaggtc tctttgattg ttggagggat taagaatcta
   102001 ggtcttgcta ttaaagcatt gacatttgat aagttggtca gttttggtga aacaatctat
   102061 ttgaacacct tatatgcaaa agattttgtg gtcaattcag gtaaaacaat tgcacagcta
   102121 ggaaaaactg ctttagaact tggtaaatca gctctagcat ggactgctca tgcagcgaaa
   102181 atgggattag caaccgcggc ggaatttgca cattctgttg cagcaggagt cgctacagct
   102241 gcaacatggg cttttaatgc agcgttagca gttttgacaa gtccaataac atggattatt
   102301 gcagcaatcg cagccttaat tgctatcggt gttttgctct atcaaaactg ggacactgtt
   102361 gttgagtttg ctaaaactgc atggcaagga ctatgtgatt ttatcagtag tatttgtcaa
   102421 gcgattggcg aatttttcag cggtctatgg acgaaactac aagaaatctt tgagccgata
   102481 ggtcaatggt ttggcgagaa attccagcaa gcatgggacg ccattgtaaa catattctct
   102541 ggcatcggag agtggttctc tggtgtattc caaggtgcat gggacgctat cgttaatatc
   102601 ttcacaccaa tcggctcatg gttcggacaa cgttgggcag atgtgactag tgcgttggct
   102661 aatatcgggg catggtttac gaatatgttc caaaaagcat ggactggctt aacaaacatc
   102721 tttagcaaac taggttcatg gtttggcgag agatgggcag atgtgactaa tgcgttatcc
   102781 agtgtttcaa actggtttgg tgagatgttc actaatgctt acaacgcagt aaaagatgct
   102841 tttagttcta ttggcgactt ctttaaaggc gtttgggata ctgttaaaag tatcttcgta
   102901 aatgctggtc agatggtcgg agaggcagta ggtggagcgt ttaagagtgc ggtcaatgcg
   102961 gttcttggaa cgattgaaaa tgtagtcaat ggcttcatcg gaatgattaa tggagtttta
   103021 ggcgttgtca gaaacttacc tggtctagga tgggttggta gtgtaagtac agttagcctc
   103081 cctcgtcttg cccgtggtgg tatcgtcgat agtccaacaa tcgccatgat tggtgaagct
   103141 ggtaaagagg cggtcgtacc acttgaaaat acaggattta tccaaacact tggacgagta
   103201 gtcagcagtg cggtagtaaa tgccatggct ggtgttagtc cacaaggtgg attctctggc
   103261 gacggcgaca tcgttatcca aatcgcaggc catgagttcg gacgggtagc catccaagaa
   103321 atcaacaagg agcatgaacg agcaggtcaa accttgctca agatttagga ggttaaatgg
   103381 cacaattgac aatcaatggg gtggctgtga agcctcccaa atcttttcaa gtcggtattc
   103441 aagatatcga tggagagaca gggcgtaacg ccaatggcga catggtgcgt gaccgtatca
   103501 cgaccaaacg caaactagac tgtgaatggg gtatgatgac tcagggagaa ttaagtcagc
   103561 ttttacatgc tgtatcatct gaattttttg aggtgtctta tccagacccc atggatggcc
   103621 aagtcacaaa gactttctat gtcggtaata ggacagctcc tagatatacc tttactgaga
   103681 agtttaaacc ttggtctggc gctaaattta atctggtaga gaggtaagaa aatggacgct
   103741 ttaactagac gacaatttga cagagccatg tttgccaagg aaaggacgct ggctattcgt
   103801 gttggtgatt atacttcacg ggatatcaaa gaggctagtt ttgagtatgg ctacatcaag
   103861 ggcgatactt ataagcctgg tggaacctgc gctggtagcg gtaaaattac ctttaccagt
   103921 atcattacca cgttcaataa gctggatacc ctgcaccctg agattggtct actggttggg
   103981 gatacctacc agtgggtcaa gatgggggaa tacttcatca acgatattga gattgaccga
   104041 aaccgcaaca caaccacact tgaacttatg gatggtatgt ttaagctcaa tcgtgagtat
   104101 gtgacagatt tgcatttccc agctgaagta cgagaggtta ttcaggaaat ctgcctgaaa
   104161 acaggcattg agttagcgaa tgactatttc ggaatcagcg cgatgcgtta tcatattgag
   104221 caagttcctg agggcaagaa actttccttt agggatatgc tgagcgctat gactcagatg
   104281 attgggatgt cttgtttctt caacagagaa ggcaagatgg aaatccgtga tttgactgag
   104341 tccaatatca cgatcaacgc tgacagttac ttcttgcatg gcttgaccaa gagtgagatt
   104401 gagtatcaga tagctggtat cacttgtaag acggacaaga agtctctgac agtcggtatg
   104461 aagacaggtc ggtctttgga actggacaat gtctttatga ctcagagcgc tttaaatgac
   104521 ttgtattaca aactgaaaaa cctaacttac tatccgtata atctcaacta ccaaggacat
   104581 ttgttacttg aggttgggca gtgggtaacc attcagacca acaagaaaga gacttttaaa
   104641 gttcctgtct taagtcagag ctttatcttt aaaggtggtc tgagaggtcg tatcagtgca
   104701 gatagtaagg ctggaaacga tacccagtat tcgtacgagg gaacgattac caagcagata
   104761 aagcaacaag atggcattga agcaaaaatc caagcgcaga ttgaagcagc agataaagat
   104821 tttgaccaaa aggtcgacaa aatcaaaaaa gactttaacg atcaagtaga attggccaaa
   104881 gccagagctg aagaagtcaa gagagaactg tctgacacta tcaatcagcg atttaatagc
   104941 tttgacaacg ggccattgaa agaaactaag cacaaggctg aggaagcttt gcgaaatgct
   105001 ggcgcaagta ccctgcttgc acaggaagct aagcggattg
//
LOCUS       DAVKXA010000002        83271 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKXA010000002 DAVKXA010000000
VERSION     DAVKXA010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.002"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            64..1545
                     /locus_tag="VW883_000128"
     CDS             64..1545
                     /locus_tag="VW883_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0273334.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1907..2902
                     /locus_tag="VW883_000129"
     CDS             1907..2902
                     /locus_tag="VW883_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0273335.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            3030..4340
                     /locus_tag="VW883_000130"
     CDS             3030..4340
                     /locus_tag="VW883_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0273336.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            4436..5338
                     /locus_tag="VW883_000131"
     CDS             4436..5338
                     /locus_tag="VW883_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0273337.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITTVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            5340..6185
                     /locus_tag="VW883_000132"
     CDS             5340..6185
                     /locus_tag="VW883_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0273338.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            6195..7514
                     /locus_tag="VW883_000133"
     CDS             6195..7514
                     /locus_tag="VW883_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0273339.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGREHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            7909..8322
                     /locus_tag="VW883_000134"
     CDS             7909..8322
                     /locus_tag="VW883_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273340.1"
                     /translation="MKNNERLGIKLSRDSVLGLREVRRLYLGSSDIPVPDGYVIEVAY
                     KQISNEIDIIDWVELNKSKIKISEISESVDIDATSLRTTLTLDTLVYEGMRDIQLKLR
                     ELTKGRVFFSFVVKLVLFASILKKKGLLEKFQEKC"
     gene            8560..8859
                     /locus_tag="VW883_000135"
     CDS             8560..8859
                     /locus_tag="VW883_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273341.1"
                     /translation="MNRNVLEFLKTETAEKISLFIRKINGLEGNVTLLSINSQDLEDI
                     KNAMLSNSNLGLKIARLDVMKKIAYASNRTHYKDGTTIMDDISSGKIHRRPKSYI"
     gene            8913..9134
                     /locus_tag="VW883_000136"
     CDS             8913..9134
                     /locus_tag="VW883_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273342.1"
                     /translation="MLKNFCQNAFISLYFIVSLLGGFSAQVDLKSFSPYQSMKIALLL
                     GVALILLQLPIMFAKLLEALKTKKGETHE"
     gene            9350..10657
                     /locus_tag="VW883_000137"
     CDS             9350..10657
                     /locus_tag="VW883_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV0273343.1"
                     /translation="MFKIKQTASLSDHYFLNTSKLRSIRWFTIGFLSILSLSSSILFK
                     GWFLQMITLSVGLIITSYIERKIKGWAQQIEPLLIVRENLLFMLRRNSFLFTATKDGA
                     ILRSAKFNYQLNDVSIVIYAFKSGDEFTKEMDNLDVLLSSALGISLSSKEIYATHVEY
                     VFVYRQPERLHVTSLPLEDDSLKIKIYDDFVIDLRKNFSMLISGASGSGKSFFTYYYL
                     TRFISQTVNGKHAKIYVIDPKLSDLYKLCQRSKMPIAHYGTSNEDAFRILRHYIKELD
                     RRMLIYNQSDLFDGIGIDLGFSPLLLVIEEYSSLIASMDSKAKKDFENMVAIVAQKAR
                     SLSMGVCIVMQQPRSDSLSTNIREQLVNAIFLGAPTRESSQMMFGTTDVPKVKKDKGV
                     GLYSTDREPPKEFHSPMFDRDVFETIFSIWKFASKDYMKDEDV"
     gene            10835..11098
                     /locus_tag="VW883_000138"
     CDS             10835..11098
                     /locus_tag="VW883_000138"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273344.1"
                     /translation="MKETVVVLAISTKKERGWIKVSTLNDCWSDLGMHFDKSKFGAVF
                     SAPGLYEVEVINNASFGQNPQYEATQCRKIGSFSELVELAKIK"
     gene            11222..12265
                     /locus_tag="VW883_000139"
     CDS             11222..12265
                     /locus_tag="VW883_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEV0273345.1"
                     /translation="MNKEVLNRAPSNSPITIHQMSNKSYSKFQEEVSLKYGFIGLKLD
                     KLSLTAEVSEEFHSEILSGNFTLYDYFGVVEPNLNRNGELASYKGQFFNDEKENWYIE
                     YTPVASIKMNKRPLKIEFTPSKVSKKNFLIVFHRMFPYMFNIAISTFHLAYDFERDLS
                     ALRVNWPKVMYRPIYKGMKLETMDFGAPKGNYHLTAYNKLKERMDSGDMAEIEIYQQY
                     DNLWRIEYKFYNEGNIKKELKNGLPFLAKIPVYIENFKGLEFNNLGVNEKIYLFALRN
                     KPELFAESDKRTVAKYKKLAESISEVNLNVFFQNALDFVEIFNQEPCLINFFEFMNSM
                     LQGDIPKLTINQE"
     gene            12281..12463
                     /locus_tag="VW883_000140"
     CDS             12281..12463
                     /locus_tag="VW883_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV0273346.1"
                     /translation="MKDTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            12465..13592
                     /locus_tag="VW883_000141"
     CDS             12465..13592
                     /locus_tag="VW883_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0273347.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWYNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(13675..13747)
                     /locus_tag="VW883_000142"
     tRNA            complement(13675..13747)
                     /locus_tag="VW883_000142"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13712..13714),aa:Lys,seq:ctt)
     gene            complement(14011..15282)
                     /locus_tag="VW883_000143"
     CDS             complement(14011..15282)
                     /locus_tag="VW883_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0273348.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            15552..15791
                     /locus_tag="VW883_000144"
     CDS             15552..15791
                     /locus_tag="VW883_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273349.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            15956..16135
                     /locus_tag="VW883_000145"
     CDS             15956..16135
                     /locus_tag="VW883_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273350.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            16278..16451
                     /locus_tag="VW883_000146"
     CDS             16278..16451
                     /locus_tag="VW883_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0273351.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            16488..16940
                     /locus_tag="VW883_000147"
     CDS             16488..16940
                     /locus_tag="VW883_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0273352.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            17231..17701
                     /locus_tag="VW883_000148"
     CDS             17231..17701
                     /locus_tag="VW883_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0273353.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            17720..18808
                     /locus_tag="VW883_000149"
     CDS             17720..18808
                     /locus_tag="VW883_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0273354.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            18789..19217
                     /locus_tag="VW883_000150"
     CDS             18789..19217
                     /locus_tag="VW883_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0273355.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            19352..20305
                     /locus_tag="VW883_000151"
     CDS             19352..20305
                     /locus_tag="VW883_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0273356.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            20307..21050
                     /locus_tag="VW883_000152"
     CDS             20307..21050
                     /locus_tag="VW883_000152"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0273357.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            21061..22857
                     /gene="pepF"
                     /locus_tag="VW883_000153"
     CDS             21061..22857
                     /gene="pepF"
                     /locus_tag="VW883_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0273358.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            23104..23658
                     /locus_tag="VW883_000154"
     CDS             23104..23658
                     /locus_tag="VW883_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0273359.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTDFSSQYGWVHAFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            23769..24437
                     /locus_tag="VW883_000155"
     CDS             23769..24437
                     /locus_tag="VW883_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0273360.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(24741..24830)
                     /locus_tag="VW883_000156"
                     /pseudo
     CDS             complement(24741..24830)
                     /locus_tag="VW883_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(24827..25360)
                     /gene="queF"
                     /locus_tag="VW883_000157"
     CDS             complement(24827..25360)
                     /gene="queF"
                     /locus_tag="VW883_000157"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0273361.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(25666..25980)
                     /gene="trxA"
                     /locus_tag="VW883_000158"
     CDS             complement(25666..25980)
                     /gene="trxA"
                     /locus_tag="VW883_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0273362.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(25997..26218)
                     /locus_tag="VW883_000159"
     CDS             complement(25997..26218)
                     /locus_tag="VW883_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0273363.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(26317..26697)
                     /locus_tag="VW883_000160"
     CDS             complement(26317..26697)
                     /locus_tag="VW883_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0273364.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(26841..27794)
                     /locus_tag="VW883_000161"
     CDS             complement(26841..27794)
                     /locus_tag="VW883_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0273365.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIESYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(27862..29070)
                     /gene="sstT"
                     /locus_tag="VW883_000162"
                     /pseudo
     CDS             complement(27862..29070)
                     /gene="sstT"
                     /locus_tag="VW883_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            29209..29769
                     /locus_tag="VW883_000163"
     CDS             29209..29769
                     /locus_tag="VW883_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0273366.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            29826..30734
                     /locus_tag="VW883_000164"
     CDS             29826..30734
                     /locus_tag="VW883_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0273367.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            30686..31276
                     /locus_tag="VW883_000165"
     CDS             30686..31276
                     /locus_tag="VW883_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0273368.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            31279..32385
                     /gene="yqeH"
                     /locus_tag="VW883_000166"
     CDS             31279..32385
                     /gene="yqeH"
                     /locus_tag="VW883_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0273369.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            32599..32910
                     /gene="yhbY"
                     /locus_tag="VW883_000167"
     CDS             32599..32910
                     /gene="yhbY"
                     /locus_tag="VW883_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0273370.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            32962..33591
                     /locus_tag="VW883_000168"
     CDS             32962..33591
                     /locus_tag="VW883_000168"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0273371.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            33591..34184
                     /gene="yqeK"
                     /locus_tag="VW883_000169"
     CDS             33591..34184
                     /gene="yqeK"
                     /locus_tag="VW883_000169"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0273372.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            34185..34685
                     /locus_tag="VW883_000170"
     CDS             34185..34685
                     /locus_tag="VW883_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0273373.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            34698..35051
                     /gene="rsfS"
                     /locus_tag="VW883_000171"
     CDS             34698..35051
                     /gene="rsfS"
                     /locus_tag="VW883_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0273374.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            35154..35900
                     /locus_tag="VW883_000172"
     CDS             35154..35900
                     /locus_tag="VW883_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0273375.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVNSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            35910..37007
                     /locus_tag="VW883_000173"
     CDS             35910..37007
                     /locus_tag="VW883_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0273376.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGSVDILDRLGIDSLAFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            37245..37499
                     /locus_tag="VW883_000174"
     CDS             37245..37499
                     /locus_tag="VW883_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV0273377.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            37503..37757
                     /locus_tag="VW883_000175"
     CDS             37503..37757
                     /locus_tag="VW883_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV0273378.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            37948..39561
                     /locus_tag="VW883_000176"
     CDS             37948..39561
                     /locus_tag="VW883_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0273379.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            39691..40317
                     /gene="gmk"
                     /locus_tag="VW883_000177"
     CDS             39691..40317
                     /gene="gmk"
                     /locus_tag="VW883_000177"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0273380.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            40342..40656
                     /locus_tag="VW883_000178"
     CDS             40342..40656
                     /locus_tag="VW883_000178"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0273381.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            40722..43118
                     /locus_tag="VW883_000179"
     CDS             40722..43118
                     /locus_tag="VW883_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0273382.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLSLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            43131..44066
                     /locus_tag="VW883_000180"
     CDS             43131..44066
                     /locus_tag="VW883_000180"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0273383.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            44059..45372
                     /gene="rsmB"
                     /locus_tag="VW883_000181"
     CDS             44059..45372
                     /gene="rsmB"
                     /locus_tag="VW883_000181"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0273384.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            45387..46127
                     /locus_tag="VW883_000182"
     CDS             45387..46127
                     /locus_tag="VW883_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0273385.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            46124..48103
                     /gene="pknB"
                     /locus_tag="VW883_000183"
     CDS             46124..48103
                     /gene="pknB"
                     /locus_tag="VW883_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0273386.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            48218..48976
                     /locus_tag="VW883_000184"
     CDS             48218..48976
                     /locus_tag="VW883_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0273387.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            48978..49427
                     /locus_tag="VW883_000185"
     CDS             48978..49427
                     /locus_tag="VW883_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0273388.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            49489..50115
                     /locus_tag="VW883_000186"
                     /pseudo
     CDS             49489..50115
                     /locus_tag="VW883_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            50183..50431
                     /locus_tag="VW883_000187"
     CDS             50183..50431
                     /locus_tag="VW883_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273389.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIDELSSN"
     gene            50562..51734
                     /locus_tag="VW883_000188"
     CDS             50562..51734
                     /locus_tag="VW883_000188"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0273390.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIVLYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            51734..53008
                     /locus_tag="VW883_000189"
     CDS             51734..53008
                     /locus_tag="VW883_000189"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0273391.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(53044..54009)
                     /locus_tag="VW883_000190"
     CDS             complement(53044..54009)
                     /locus_tag="VW883_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0273392.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(53990..55444)
                     /locus_tag="VW883_000191"
     CDS             complement(53990..55444)
                     /locus_tag="VW883_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0273393.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            55820..57703
                     /locus_tag="VW883_000192"
     CDS             55820..57703
                     /locus_tag="VW883_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0273394.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSIPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            57852..58739
                     /locus_tag="VW883_000193"
     CDS             57852..58739
                     /locus_tag="VW883_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0273395.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVLQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIEFNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(59059..59676)
                     /locus_tag="VW883_000194"
     CDS             complement(59059..59676)
                     /locus_tag="VW883_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0273396.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(60091..60304)
                     /locus_tag="VW883_000195"
                     /pseudo
     CDS             complement(60091..60304)
                     /locus_tag="VW883_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(60789..60869)
                     /locus_tag="VW883_000196"
                     /pseudo
     CDS             complement(60789..60869)
                     /locus_tag="VW883_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            60985..61878
                     /locus_tag="VW883_000197"
     CDS             60985..61878
                     /locus_tag="VW883_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273397.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLKVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            61875..63074
                     /locus_tag="VW883_000198"
     CDS             61875..63074
                     /locus_tag="VW883_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0273398.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(63487..64254)
                     /locus_tag="VW883_000199"
     CDS             complement(63487..64254)
                     /locus_tag="VW883_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273399.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(64271..64966)
                     /locus_tag="VW883_000200"
     CDS             complement(64271..64966)
                     /locus_tag="VW883_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273400.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(64971..65336)
                     /locus_tag="VW883_000201"
     CDS             complement(64971..65336)
                     /locus_tag="VW883_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0273401.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            65476..65949
                     /gene="nrdR"
                     /locus_tag="VW883_000202"
     CDS             65476..65949
                     /gene="nrdR"
                     /locus_tag="VW883_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0273402.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            65950..67119
                     /locus_tag="VW883_000203"
     CDS             65950..67119
                     /locus_tag="VW883_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0273403.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            67120..68016
                     /gene="dnaI"
                     /locus_tag="VW883_000204"
     CDS             67120..68016
                     /gene="dnaI"
                     /locus_tag="VW883_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0273404.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSDVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            68013..68726
                     /locus_tag="VW883_000205"
     CDS             68013..68726
                     /locus_tag="VW883_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0273405.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            68740..70050
                     /gene="der"
                     /locus_tag="VW883_000206"
     CDS             68740..70050
                     /gene="der"
                     /locus_tag="VW883_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0273406.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            70141..70476
                     /locus_tag="VW883_000207"
     CDS             70141..70476
                     /locus_tag="VW883_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273407.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            70617..70952
                     /locus_tag="VW883_000208"
     CDS             70617..70952
                     /locus_tag="VW883_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273408.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMLDLRRE
                     LGKSKGGRH"
     gene            71137..71928
                     /locus_tag="VW883_000209"
     CDS             71137..71928
                     /locus_tag="VW883_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273409.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLKKYEDNV"
     gene            71921..72562
                     /locus_tag="VW883_000210"
     CDS             71921..72562
                     /locus_tag="VW883_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273410.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            72566..73216
                     /locus_tag="VW883_000211"
     CDS             72566..73216
                     /locus_tag="VW883_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0273411.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            73227..73514
                     /locus_tag="VW883_000212"
     CDS             73227..73514
                     /locus_tag="VW883_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273412.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            73660..76173
                     /gene="secA"
                     /locus_tag="VW883_000213"
     CDS             73660..76173
                     /gene="secA"
                     /locus_tag="VW883_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0273413.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            76254..77285
                     /locus_tag="VW883_000214"
     CDS             76254..77285
                     /locus_tag="VW883_000214"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0273414.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            77287..78318
                     /locus_tag="VW883_000215"
     CDS             77287..78318
                     /locus_tag="VW883_000215"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0273415.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            78357..78725
                     /locus_tag="VW883_000216"
     CDS             78357..78725
                     /locus_tag="VW883_000216"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0273416.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVIASVILEENHES"
     gene            78715..79818
                     /locus_tag="VW883_000217"
     CDS             78715..79818
                     /locus_tag="VW883_000217"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0273417.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVNGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHIKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            79837..81852
                     /gene="recG"
                     /locus_tag="VW883_000218"
     CDS             79837..81852
                     /gene="recG"
                     /locus_tag="VW883_000218"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0273418.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            82168..83148
                     /locus_tag="VW883_000219"
     CDS             82168..83148
                     /locus_tag="VW883_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0273419.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHETMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        25074 a        15267 c        18554 g        24376 t
ORIGIN      
        1 tattctttgt ggtataattg caagaggttt aatccgataa tttataaaga gagaaagata
       61 ttcatgagag atttattatc taaaaaaagt cataggcaat tagaattatt agaattatta
      121 tttgaacata aacgttggtt tcatcgttct gaactagcag agttattaaa ttgtacagaa
      181 cgtgcagtca aagatgatct atcccatgtt aaatctgctt ttcctgactt gatttttcat
      241 tcttctacta atggtatacg cattattaat accgatgata gtgatattga aatggtttac
      301 catcatttct ttaaacattc aactcatttt tcgattttag aattcatctt ctttaatgaa
      361 ggttgtcaag ctgagagtat ttgtaaagaa ttttatatca gttcatcttc gctctatcgt
      421 attattagcc aaatcaataa agtgattaaa aggcaatttc aatttgaagt cagtctgacc
      481 cctgttcaaa tcattggaaa tgagagagac attcgttact tttttgcaca atatttttca
      541 gaaaaatatt atttcctaga atggccattt gaaaattttt catcagagcc actatctcaa
      601 ttgttagaat tggtttataa ggaaacaagc tttccaatga atttgtcaac gcatagaatg
      661 ctaaagttgc tcctagttac gaacctatat agaataaagt ttggtcattt tatggaagta
      721 gataaagatt cttttaacga ccaaagtttg gattttttaa tgcaggcaga aggaatagaa
      781 ggtgttgctc agagttttga atcagaatac aatatctctt tagatgaaga agttgtttgc
      841 caattatttg tgtcttactt tcaaaaaatg tttttcatag atgaaagtct ctttatgaaa
      901 tgcgtaaaaa aggatagtta tgttgaaaaa tcttaccatc tattgagtga ttttattgat
      961 cagatttcag tcaagtatca gattgaaatg gagaataagg ataatctgat ttggcatctg
     1021 cataataccg cacatctgta tcgtcaagag ttgtttactg agtttatttt atttgatcaa
     1081 aaagggaata caatcaggaa ctttcaaaat atttttccaa aatttgtttc agatataaaa
     1141 aaagagcttt ctcactattt agagactctt gaggtttgtt ctagttcaat gatggtaaat
     1201 catctatctt ataccttcat cactcatacc aaacatttgg tgattaattt gctacaaaat
     1261 cagcctaaac taaaggtttt ggttatgagt aattttgatc agtatcatgc aaaattcgtt
     1321 gcagagacac tttcttatta ctgtagcaat aattttgaac tggaggtttg gaccgaatta
     1381 gaattatcaa aggaatcttt agaagattca ccttatgata ttattatttc caattttatt
     1441 attcctccta ttgaaaataa gagactcatc tattcaaata atataaacac ggtctcactc
     1501 atatacttgt taaatgccat gatgtttatt cgattagatg agtaaccaaa aataacaaaa
     1561 aaacgctatt tcgcgtttga actgtacctc aaaagttaga cagaaaaagt ctaattttta
     1621 gggtgttttt gttaagaaaa gaccttcaat catttaagaa aaatgtacat ctagatttat
     1681 agccctctaa aactcttgct ttttttgtag aagatacgaa aaaagccatg aaaccaaggc
     1741 ttttcctgtt ttatgtagat gtttacacat gaaaattgaa gtattttcaa aagctaattg
     1801 gagtgatttt attcatgatg ggataaatga tctggccaaa aatgattgag aaatagttgc
     1861 ttaaaaagca tttgcatgat actatatatt gaaaggaggt gataatatgg tagaacaaag
     1921 aaaatcaatt accatgaaag atgttgcttt agaagcagga gttagtgttg gaactgtttc
     1981 acgtgtaatt aataaagaaa aaggcattaa agaagtaact ttaaggaaag ttcaaagggc
     2041 tataaaaaca ttggactata tccctgataa ttatgctcga ggtatgaaaa agaatagaac
     2101 agaaactatc gctttgatta ttccgagcat atggcatcca tttttttcgg agtttgccta
     2161 tcatgttgag aaagagttat taaaatataa ttataaatta tttatttgta acgctgatag
     2221 cgattcacaa aatgaaatcg aatatatcga aatgttgaaa caaaataaag tggatggaat
     2281 tattggtatt acatattctg atattgacaa atatatttta tctgatttac cgtttgtaag
     2341 tatagataga catttttcgg aaaatgtatg ctatgttact tcagcaaatt acaaaggagg
     2401 acaaactgca gcagaggaac tggttagaag ggataataag caccttgctt ttattggttc
     2461 aattaatatg tatgagaatg agactatact cagaagtaaa ggattcagag aaaaagctaa
     2521 ggaattagga gtagatgtct ataattttga aatgaaagaa cctttaataa atcctgaaga
     2581 tcagataaga atttttttgc aatctcataa agaaattgat ggtatattta caataaatga
     2641 tatgatggct ctgagagtta ttagtgttat gaaagaactg gggaaaatag cacctgatga
     2701 ttaccagata attgggtttg atggtttaaa aacttctgtc gatcaatctt atctagtgtc
     2761 tacaatagtt caagatattg gtatgatggc aaaagaatct gttgcaatga tactgaaaat
     2821 gattaagcga gaagagattc tagaaaaacg aatcgtaatt cccacatatt tttggggaga
     2881 taaaacaaca aaaaaaattt aaaaagcgct tgacaattaa tgaaagcgct gttataatat
     2941 aatcaacaaa tgaaacgttt caaaaaatag gctagaagct tgtttaaaaa ataaataaaa
     3001 aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg tacaatgtta tctgttgttg
     3061 cggggctatc gttagctata cttgcaggtt gtagtggagg aactaactca aaacaagcga
     3121 gttcttcaaa tgatattaaa gtctgggtac aattctctga cgaaacaaat gaaggaaaag
     3181 cttggcaaaa agttgttgat aactttaatc aatcaggaaa aagtaagtac aaggttgtaa
     3241 ctgagtatat tcctcgtagt ggtagtggtg gaggatatga agacaaggtt aatgctgcta
     3301 ttacgactaa tagtcttcca gatgttatta cccttgatgg accaaatacg gcagcttatg
     3361 caaaatctaa agtaattact ccgctagatg attatctaaa agataataat atggatgatg
     3421 ttttggacag tattaaacaa cagggaactt ataatgggaa attctatgca tttggatttt
     3481 ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt caaagaggcc ggaattgcgg
     3541 aatcagagct tccaacgcta gaaaagccat ggacatggga cgaatttaat acgattgcta
     3601 aaaaattgaa agatcattat aacaaaccag caattgattt tcgtattaat tcaaacgatg
     3661 aaatgttgcc atatgcttat atgccgttga tttggtcaaa taatggttct gtcgtaaacg
     3721 aagatggaac aaaggcagaa ggatacttca actccaaaga gagtgtagaa gcagttcaat
     3781 tcattcaaaa tcttgtaaaa gaaggctata caactgttag tccagtcgaa aaaggttttg
     3841 aaacaggaga gtatccaatg cttttgagtg gttcttggac gattgctgac atgaatacaa
     3901 actacaaaga tattgatttt ggtatccttc cttacccagt atctagtaag acgaaaaaat
     3961 tagtatcccc ttcaggtagt tggcaattag ctgtgacgac aaaatctgat aaaaaagagg
     4021 ccgcatctga atttgttaaa tttgctacaa atacagaatc aagtgaaatt attagcttgg
     4081 ggaattcggt ccttccaatt cgtaaatcta caattgaaaa tatcaaagat aaagtatccg
     4141 aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc tcatgctcgc ccagttgttg
     4201 tagcatatcc tcaggtttct cgagcttttc aacaagcaat gcaagatatt agctattatg
     4261 aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac aaaagaaatg caaactgcta
     4321 ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga aggaaaatgt ttggaactac
     4381 cttccccttt cttgttaata gcctagtttg atatatatga ttaaaggaga tggatatgag
     4441 taaagaaact gttgtggata caaaaagacg tgaaaaaata aaggataaca tattaggtta
     4501 tagtttttta gctccagctt taattttatt aggtatcttt ttagtaattc cagttggaat
     4561 ggtcatttat tacgctttta cagattatta tttgttgaca ccagatgaaa gaaaatttgt
     4621 tggacttgaa aattttattc gattaacaaa agatccgatt ttcttaaaga gcttcttgaa
     4681 tactttgaaa tttgttgttt ggattattcc agttcaattg ggagcggcct taggaatggc
     4741 tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt aaagtggctt tttttgctcc
     4801 agttgtcatg tccttggtag ttatttctat tctttggctt tatcttttaa atccaaatag
     4861 tggcttatta aatgctattt taaataaggt aggtattgct tctcaacctt tcttgactag
     4921 tcctaaacaa gctatgtatg caattgtttt tgtttctgct tggcagggtg caggttatca
     4981 gatgctttta tttttaggag gaatgcagaa tattccacaa gatgtctatg aagctgctga
     5041 attagatgga ttctcaaaat gggctcagtt tcgttatatc acgatgcccc tactaaaacc
     5101 aacagccctg tttgtattgt taacaacttt aatttctgct tttaagctga ttgtacaacc
     5161 aatggttatg acgcaaggtg ggccattaaa ctcaacaatt actacggtgt actatattta
     5221 tcaacaaggt tttactgatc gtcttgtagg atattctagc tcaatcgctt tagtatttac
     5281 aacgttaatt ggtatgatta gcttagtaca acgtcgcgtt ctgaaggagg atgactaaga
     5341 tgaaacgatt taaaccaaca acaatcttag aatatattct gttaacttta ttggcaggac
     5401 tcttcctttt tcctatggtt tggatggtag tttcagctat gaagccagaa gcggatgttt
     5461 ataaaaattt gactagttgg caagccttct taccaagttt aaatcccgct gattggttta
     5521 aaccttatca ggaagtattt gagcgcttta gtatttttac atatctaggg aacagcattt
     5581 tttatgctgg aacgtttgct attggttcta ttattgtcaa tgcactggcc ggtttcgctt
     5641 ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg tttcttactt gctttactta
     5701 ttattccagt ggaaactgtg ttaattccac aatttaccat tatcaattcc ttaggtttgg
     5761 tcaataatcg tcttgcagtt attattccag gattggcgag tgtatttaat atttacttat
     5821 ttaggaattt ctttattgca attccagaag agattcttga gtctgcaaag atggacggag
     5881 caagtatcgt tagaattttc tttagaatta tgcttccaat gtctaaacct gcagttgcta
     5941 cagttggtgt tttatcattt atttcaagct ggaatgatta tatctggcca ttgatggttt
     6001 tgacagattc ttctaaattt tcaatgcagg ttgcaattac aactattaat acaactcaac
     6061 cagtttatat caatcaggta atggctgtat taactatttc aacgattccg ttgattttgg
     6121 tctatgtagt cgctcagaaa tatattgttc aaggtctggg tggttccgga actggaataa
     6181 aataggatat acttatgata aataaaacat ttacagtaga aaaagccaat cgttttatag
     6241 cagaaaataa acatctcgtt aatactcaat ataagcctga agaacatttt tcagctgaga
     6301 ttggttggat caatgatcca aatggatttg tttattttcg tggagaatac catctctttt
     6361 atcaattcta tccatatgat agtgtttggg gacctatgca ctggggacat gctaaaagta
     6421 aggacttggt gacttgggag cacttgccag tggcacttgc tcctgatcaa gattatgacc
     6481 gaaatggttg tttctcaggc tctgccattg tcaaggatga tcgcctctgg ctcatgtaca
     6541 ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca aaatatggca ttttcagacg
     6601 acgggattca ctttgaaaag attgaacaaa atccagttgc aacaggagca gacttgccag
     6661 atgagttgat tgctgctgat ttccgtgatc caaaactctt tgaaaaagat ggacgctatt
     6721 actccgtagt agctaccaaa cacaaggata atgtgggctg tatcgttcta ctagggtccg
     6781 ataacctagt agaatggcag ttcgaatcca tctttttaaa agggagagaa caccaaggct
     6841 ttatgtggga atgcccagat tacttcgagt tagatgggaa agattgcctt attatgtcac
     6901 ccatgcgtta tcagcgtgag ggagactcat atcataacat caactcatcg cttttgttca
     6961 cgggtaaggt agattgggga gaaaaacgtt ttatcccaga atcagttcaa gaaatcgatc
     7021 atggccaaga cttctatgcg cctcaaacat tgttggacga tcaaaatcgt cgtatcctga
     7081 ttgcttggat gcagacatgg gggcgtaccc ttccaaccca tgaccaagaa cacaaatggg
     7141 catgtgccat gactttacct agaattctaa gattggaaga tggcaaacta agacaattcc
     7201 ctgttaaaaa aggccaatat caaatccaaa tagataaaga ttgtcattac cacttaggaa
     7261 atgatacaga ttatcttgaa tttggttatg acagtaatgc gcagcaagtt tacattgatc
     7321 gtagccatct tattcaaaaa attctaggtg aagaagaaca ggacactagt cgacggtatg
     7381 tagatattga agctaaagaa ttggaagttg ttctagataa aaattccatc gagatttttg
     7441 tcaatcaagg tgaagcaagc ttgactgcaa cttattactt aacggtgcca gctgagctat
     7501 cacgaattga ttaaaaatta agttatttct cctaaagaaa aagttctctt tctaaaatag
     7561 tggaaagagg actttttgtg ttttgggtat ataagcttag tttatggtat ttgtaaaatt
     7621 ggtgttggat tatgatttaa gctagttttc taaagaattt gaaaaaaatt ttatttaagc
     7681 aaaaaaacct tggttccaag gcttttcctg ttgtatttag atgcccccta caggaattgt
     7741 aggagatatg ttgtttagat gttcttgatt ttctggtgtt ttgtaacgtt taaatgagtt
     7801 ttttgagttt gttggtgggg cgttgcccgg caattgcccg acttattgtt tgaaaaagaa
     7861 tttaaaatat ggtatagtta attatagatt aacacttggg gggaatagat gaagaataat
     7921 gaaagattag gtattaaatt aagtagagat agcgttttag gattgaggga agttagaagg
     7981 ctttatttag gcagttcaga tatcccagtg cctgatgggt atgtgattga agttgcttat
     8041 aaacagatat caaatgagat tgatattatt gattgggtag agttgaacaa gtcaaaaatt
     8101 aagataagtg aaattagtga aagcgtagat atagatgcca ctagcttgag aacaactttg
     8161 actttagaca cgttagtata tgaaggtatg agagatatac agttaaagtt gagagagctt
     8221 acaaagggga gagtattctt ttcatttgta gtgaagttag ttttatttgc ttctatttta
     8281 aagaaaaaag gtttactaga aaaatttcaa gaaaagtgtt aatcaagtat tgacttttta
     8341 gttgagttca agtatacttt aattagagag atttctctct aaattttttc gcttcttttg
     8401 tgttaatcaa tgacaaactc tttgtcttat tttttaacgc ttgggtgtgt taatcaaaga
     8461 tgtatatatt ggaggatgaa gatgaaagct agagcttcac cgttgaattg attttgtttc
     8521 tagaaaaaat caataattag aaaaaataag aggtaagaaa tgaatagaaa tgtactagag
     8581 tttctgaaaa cagagacagc tgagaaaatt agccttttca tcaggaaaat aaatggatta
     8641 gaaggaaatg tgacattact ttctattaac tctcaagatt tggaagatat taaaaatgct
     8701 atgctttcca attctaatct cggattaaaa attgcgagac tggatgtgat gaagaaaata
     8761 gcatatgctt ctaatcgtac tcattataaa gatggaacga ctatcatgga tgacatctca
     8821 tctggtaaaa tacatcgtcg ccctaaaagc tatatctaat aaggaaggtt aatccctctt
     8881 ccttattaga tatttaaaaa aaggagaaaa atatgcttaa gaatttttgt caaaatgcct
     8941 ttattagttt atatttcata gtgtctctgc taggaggatt ttcagctcag gttgacctaa
     9001 aatccttctc tccttatcaa tctatgaaga tagccttgtt attaggagtt gctttaattt
     9061 tattgcaact tccaataatg tttgctaaat tattagaagc tttaaaaacc aagaaaggtg
     9121 aaactcatga atgacatcgt aaaaatgaga ttagcctttt gtatcactat aatattgatg
     9181 gcatgctctg tttttgtgtt tactcctgtt ggagaaggca tgtccctact ttgctcaatt
     9241 tttgctaccc cgtttttatt tatttttgtt ttctattttt ttaaaataaa attaagaatt
     9301 ttacttatta ttatcaagga tttcataaaa aaatttagat aggtataaga tgtttaaaat
     9361 taaacaaacg gcttctttgt ctgatcatta ttttttaaat acatctaaat tgagaagtat
     9421 tcgctggttt actataggat ttttgagcat attgtccctt tctagtagta ttctttttaa
     9481 gggatggttt cttcaaatga ttacattatc cgttggattg attataactt cgtatattga
     9541 aagaaaaatc aagggatggg ctcagcagat tgaaccgctg ttaattgtca gagaaaacct
     9601 tctatttatg cttcgcagaa attcctttct ttttacagca acaaaagatg gcgctattct
     9661 tcgttcagct aaatttaatt accaattgaa tgatgtttca attgtaatct atgcatttaa
     9721 gtctggggat gaattcacga aagagatgga caatttagac gttctcctaa gtagtgctct
     9781 aggaataagc ctatcgtcaa aagaaattta tgcgactcat gttgaatatg tttttgtata
     9841 tagacagcct gaacgtttac atgttacctc cctccctctt gaagatgata gcctgaaaat
     9901 taaaatctat gatgattttg ttatcgattt gagaaaaaac ttttccatgc ttatatcggg
     9961 tgcctccggt agtggtaaat ctttttttac atattattac ttgactcgtt tcatatctca
    10021 gaccgtaaat gggaaacatg caaaaatata tgtgattgac ccaaagctgt ctgaccttta
    10081 taagctttgt cagcgttcta agatgccgat agcccattat ggaacgagta atgaggatgc
    10141 ctttagaatt ctgcgtcact atatcaagga gctagataga cgtatgctaa tctacaatca
    10201 aagtgacttg ttcgatggta ttggcataga cttaggtttt tctcctttac ttctggtaat
    10261 agaggagtat tcatcgttaa ttgcttcaat ggatagtaaa gctaaaaaag attttgaaaa
    10321 tatggttgct atcgttgctc aaaaagcaag gtctttatct atgggggtct gcattgttat
    10381 gcaacaaccc cgttccgata gcctttcaac aaatattcgt gaacaattgg tcaatgctat
    10441 atttcttgga gccccaactc gcgaatctag ccagatgatg tttggcacaa cagatgtacc
    10501 caaagttaag aaggataaag gagttgggct ttattctaca gatagagagc ctcctaagga
    10561 attccattcc ccgatgtttg atagagatgt gtttgagaca attttttcaa tttggaaatt
    10621 tgcttctaaa gattatatga aggatgaaga tgtatgagaa ttttaagcgt tttgaagatg
    10681 aataaaattc ttttattcat tttcaaaatg ccattgtgca gccggcgaac aacaaggccg
    10741 gtcggacgta acgtccgaat aaatgtattt atgtccaata ctgattgacg ttaaaagctg
    10801 tatattattt taaataagga aggatttttt aacaatgaaa gaaactgttg ttgttctagc
    10861 tatttctact aagaaagagc gaggctggat caaggtctcc acccttaatg attgttggag
    10921 tgacctaggt atgcatttcg ataaatccaa atttggagct gtcttctctg ctccaggcct
    10981 ttatgaggtt gaagtgatta ataatgcttc atttggacag aatccccaat atgaggcgac
    11041 tcaatgtaga aaaatcggga gtttttccga attagttgaa ctggcaaaaa ttaaataatt
    11101 tatatttggg taaggctgga cctgccagct ttgctggcaa gtggagcgtg gtcagtggaa
    11161 cggcagtctt gccctaaaat ttaagtatat agaatgtttt gttttttgaa ggagaaattt
    11221 catgaataaa gaagttttaa atcgggcccc ttctaatagc ccgataacga tacatcaaat
    11281 gtctaataag agttactcta aatttcaaga ggaagtatct ctgaagtatg ggtttatcgg
    11341 tctgaaattg gataagctaa gtttgaccgc tgaagttagt gaggaatttc attctgagat
    11401 tcttagtggg aacttcacct tatatgatta tttcggtgta gttgagccga atttaaatag
    11461 aaatggtgaa ctagctagtt ataaagggca attctttaat gatgaaaaag agaattggta
    11521 tatcgagtat acccccgttg cgtcgattaa gatgaacaaa agacctttaa agattgaatt
    11581 tactccttca aaagtttcaa aaaagaattt tttaattgtc tttcatagaa tgtttccgta
    11641 catgtttaac atcgcaatct ctacttttca tttagcctat gattttgagc gagatttatc
    11701 tgctttacgt gtaaattggc caaaagtaat gtatcgtcct atttataagg ggatgaaact
    11761 tgagactatg gattttggtg ctcctaaagg taattatcat ctaactgctt ataataaact
    11821 taaagaacgt atggatagtg gagatatggc agaaatagaa atttatcagc aatatgataa
    11881 tctatggagg attgagtata aattctacaa tgaaggcaac ataaaaaaag aattaaaaaa
    11941 tggattacca ttcttagcta aaattccagt gtatattgaa aatttcaaag gcttagaatt
    12001 taataattta ggagttaatg agaagattta tcttttcgct cttcgtaata aacctgaatt
    12061 atttgcagaa tctgataaac gaacggtagc taagtataaa aaacttgccg aaagtatctc
    12121 tgaagttaat ttgaatgtct tttttcaaaa tgctttagat tttgttgaaa tctttaatca
    12181 agagccttgt ctgataaatt tttttgagtt tatgaattct atgttacaag gcgatattcc
    12241 aaagttaaca ataaaccaag aataataaga ggggaacagt atgaaagata cgatttctaa
    12301 taaggatttg atttccatgg gctatagacc atcaacagca aatgctatta tccatcaggc
    12361 gagagaatta cttgtatcac gaggctatac attttataat cgcaaacgtt tgatggttgt
    12421 tccaaaaagt gttgtgaaag agttgttggg aatggaattg tgaaatggct tatatcgagt
    12481 ataaacagcg tgggaagaaa aggctttggt ccttttctat aagagaaaga agcaagagcc
    12541 tactccataa aagcggattt aaaacaaaac gagaagctaa aatagaagcg gagaaagttc
    12601 ttcataagtt aaatactggg agtgtcttaa gctctagtat gactttatcg gagctttata
    12661 atgaatggct tgatttaaaa attttaccta gcaatagaag tgtagttact aaaaaaaaat
    12721 atctcatgag aaagaaggtc atcgaaaggt tatttggaaa taagcctgta tcacaaatta
    12781 agcctagcga gtatcaaaaa attatgaatg agtatggaga gactgtatcg agaaatttct
    12841 taggaagatt gaattcttgt attcgggcaa gtatacagat ggctattgct gataaggtga
    12901 taatagagga ttttactgct tatgttgagt tgttctcttc taagagtgga caaaaggttg
    12961 aggaaaagta tttgcatgct gagtcagatt atcaaaaagt tttagtatat ttgaaaaata
    13021 agtttgatta tcaaaaatct attgtaccgt atgtaattta tttccttttt aaaactggca
    13081 tgcgtttctc cgaattgatt gctctaactt gggatgaagt tgacgagctt aatgagcaac
    13141 ttaaaactta tcgtcgttac aacactgcta ttcataagtt tactccacct aaaaacaata
    13201 cttcaataag attagttcct attacttcag atatgctttc cttgttaaaa acattgaaaa
    13261 tattgcaatt aaaaacaaat aaagaattaa atattgataa tgaaaataat ttgatttttc
    13321 agcattttgg ctatgtctac gatgttccag atattgcaac agtcaataaa gctataaaag
    13381 taatgttgaa ggaattgcaa atttttccat tgattactac caaaggagct agacacactt
    13441 atggtagtta tttatggtat aataatattg atttgggagt tatagcgaaa attttaggac
    13501 ataaagatat ctccatgttg attgatgttt atgggcatac cttggaggaa aaaattagtg
    13561 aggagtttat ggctgtgaaa agtttgttgt aaaaacacgg caaattgcac gacaattttt
    13621 aaaaggaaag caaaaaaagc cctatattat aaggcttttc ctgttgtatt tatatgcccc
    13681 ctacagggat cgaacctgtg acccacggat taagagtccg ctgctctgcc agctgagcta
    13741 aggaggcaaa gaaaaagctg tattggtgcc gaaacttcac ggtttgtatt gaacccgcgc
    13801 aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga cggcctacat
    13861 gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa cacttaagtg
    13921 tgaagtcgta caccacagcg tttctatact tatatgatac cactttttca aaaaaaatca
    13981 agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaacgat cgatagcttc
    14041 ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga aatagtgatg
    14101 attacgaatt ttttctggca gatagtcttg cttgacccaa tttccaggat agttgtgtgg
    14161 atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc catcacgcag
    14221 gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct tatccatagc
    14281 tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat tggcaatgag
    14341 aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca cggtatgaat
    14401 ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca agcgacgagc
    14461 gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac tggcatccac
    14521 atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac cgtctccatc
    14581 cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta aggtgatgtg
    14641 gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg agttaaaggc
    14701 agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct catctagttc
    14761 tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg cctctttgac
    14821 gtcttggtta gacagaggtt ccaactcgaa aatttgaact cggctacgaa tggcaggagt
    14881 gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc cactttccaa
    14941 gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt ctagcaatag
    15001 gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct ttttactatc
    15061 aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg cagaggcaat
    15121 actggttttg ccgattccag gagggccata tagaatcatg gaggacaggc ggttggcttc
    15181 caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga tgacctggtc
    15241 gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc tttctaacgt
    15301 ggatttgagt agaatgactc atctactata tcttactatg tccattctag cctattagtt
    15361 gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt ttactattta
    15421 atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct caaaatagga
    15481 tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg aatgtcattg
    15541 tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca agtcaggaaa
    15601 ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt atttcaggga
    15661 aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg tacgaaaaca
    15721 ttaaatctaa acttgatttt gcttaccaag aagtttattc taataatggg ttgaaaaaat
    15781 atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcatccttgt aataactgtt
    15841 gaaaatccta atttcgaaga cttgagagtt aatcatactc aatgaaaatc aaagagcaaa
    15901 ctaggaaact agccgcaggc tgtacttgag tacggtaagg cgacgttgac gtggtttgaa
    15961 tttgattttc gaagagtatc agtttgtaaa aattggagat aaaaaatata gagtacgcag
    16021 tggtcctatg attcattcaa ctccgcctca atctgtctta gatcgagata cttttacaat
    16081 tgactataca gatgatgaat tgctcgataa agaagcagtt tttactactc attagaaaaa
    16141 taggtctgaa taaattggtt tcccttagaa ccacatctag gggcttttat gtataataga
    16201 ataataagta tcactccttt acaatacgtg taacacgtgt tataatggtg ttgtcaggag
    16261 gtaaaagcgc tatacctatg acacaaaaag agatggttaa actccttacg gcccatggtt
    16321 ggataaagac tagaggcggt aaaggctccc atattaaaat ggagaagcaa ggggaaagac
    16381 ctatcacaat ccttcatggt gagctgaata agtacactga aagagggata ggaaagcaag
    16441 ctgggttgta aaattcagtc cctgcttttt gatatggagg tagtgaaatg ttagttacgt
    16501 atccagcttt attttattat gacgacacag acggaacaga agcgacttat tttgtccatt
    16561 tcccagattt tgaatactca gctacacaag gagaggggat ttctgaggct ttggctatgg
    16621 ggtcggagtg gctagggata actgttgcag atttgataga gagtgatgga gagttacctc
    16681 agccatcaga tatcaatagc ttgtctttaa ttgataatga tccttttaaa gatgatgaag
    16741 atttcgtgtc aacctatgac cttgataaat cttttatttc tatggtatct gttgatgtat
    16801 cagaatacct aggaagtcag gaacccatta aaaagacttt gaccatacca aaatgggcag
    16861 ataagttggg acgagaaatg ggacttaact tttctcagac tttgacagac gctattgcag
    16921 ataagaaagt tcaagcctaa gattaagcgt ggtatcgtgg taatagtcaa taaaaaagca
    16981 cgtccacttg tgctagttac tcgcctattg attttataga tttattagcc ctttcgcggg
    17041 ctttttatat tgatttttat gagaaatgaa gaaatcagac ttttaagaaa atcactgata
    17101 ccaagggttt aaatgaggta atatggtata attaggacat aaaataattt tgtggtaaga
    17161 tggtagtatc tattttagca tatttccgag caatcggggc gattaaagag tcgcatagaa
    17221 agaggacaaa atggcaacat acggattttt agatgtttta gaggaagagt tggacaagaa
    17281 ctttcccttt gactttgaga ttagctggga caaacgcaac catgcggtag aagtgagttt
    17341 tctattggaa gcacaaaatg ctgcaggtgt ggagatggtg gatgaagacg gagaggtttc
    17401 atcagatgac attctttttg aggaagcggt ccttttctac aatcctgcta agtcaaccgt
    17461 caatgcagaa gactatttaa cggttatccc ttatctacct aaaaaaggat tttctcgcga
    17521 gtttttagct tattttgccc ttttcctcaa agatactgcg gaagttgggc tagataccct
    17581 catggacttt ttggaagatc cagaagcaga ggaatttgtt atggaatgga atcaagaagt
    17641 ctttgaagaa ggaaaagttg gcttggaaga gggagaattt tatccttatc caagatacta
    17701 ggagttggtt ggaggtgtta tgaagaaaat tgggacttat ttggtttatg tgctagctgt
    17761 tgtctttatt atgctagctt ttgcttgtgg aacaatcgca tttgcagagt tggggtattc
    17821 cgcagtttta gcctttactt ttggttatgc cttcgctctt ctaagcatgt atttaatctt
    17881 tattcttcat gagctgggtc atgctttttg tggctacttg acaggctatc ggctggtggc
    17941 ttttggatta ggacatttta ttttgaccaa aaagtcaggc aggtttcatc ttagtagaac
    18001 agccattctg aaaaatgttg gtgctcaata cattggttta aaagaggatg aaagcgatca
    18061 aagaatcatc ctgatgcttt caggaggctt gatggttcat ctcggcttga tattattggc
    18121 gatagtgttt ggatttttga caagaagctg gtattttgca gggacttgga tttttcttaa
    18181 tttatctttc ttcctaaata acattttgcc agtcgacatc accgatggag caaaaatttg
    18241 ggaattacta caacaccctg aaaataccaa atacgcctac ctggtattga gacattctgc
    18301 tcaaactttg ctggctcctc aagaatatga tttgaaagac tttgttcaag cagttcctga
    18361 ggatgcacga gggagttttg cggatggtgt attaggtatg caaggtgaag tttccatttt
    18421 ggaagggaag gaagaagtag ctaaacagca gtttcaagca ttacttgaga ggacaactac
    18481 tccgatgatg cagacagttg cccaactatc cctgcttcat atcgccttgt tggaaggaga
    18541 ttttgagcaa gcggagcaat atgctagtat tcgacaggtc aaatcgtttc tgtctctcaa
    18601 actgtccaat cttcaagtga tacaagcctg gtatcaatta aaggtgaaga aagatgtaga
    18661 tcgaactcgt aaggctctca agattgctag acagaaaatg gatagtagtc gaatgttgag
    18721 ggacgagaaa cgctattatg aaaacttgtt agcagagctg gaaaaggaaa tgttagaagg
    18781 aactgaagat ggaactagaa atttctgatt tccaaggttg caagattgcc ctcttttgtg
    18841 gggataagct actgacgatt ttgcgtgatg acaaggacga tatcccttgt cccaacatgt
    18901 gggagttgcc aggtggtggc cgtgaagggg acgaaagccc ttttgaatgc gctcggcgtg
    18961 aagtttatga ggaactggga attcatttag atgaagactg tctgctttgg agcaagattt
    19021 atcctagcgt aatttttaaa ggcaagaaat cggtctttat ggttggtcag ctaagacaag
    19081 aacaatttga caatatcatc ttcggagatg aaggacaggg ctatcagctg atgaatgttg
    19141 aggaatttct tagttccagt caagttgtgc ctcagttgca agagagatta aaagattatt
    19201 taaaagtaag tgattagaaa ggatggttca gttaaatttc taaactgaac ccgccctaaa
    19261 cactgtgcca aaaagataaa cttctcttag acacaagcgt cttcagagaa tttcctattt
    19321 tggttttgtg ttttacgggc ttggtatctt aatgatggaa acatggcaag agttaaaagt
    19381 tacagtgaag cgtgagggag aggagttggt ttccaatctc ttgattgagc tgggagcgca
    19441 aggtgttgcg attgaagaca gtatggacta tgtgggaaat gttgaccgct tcggcgagat
    19501 tttcccagag gtcgagcagc aagaagaaat cgtagtgaca gcctactacc ctgacacggt
    19561 ggatgtgaca gtggttgagg cggacttgca ggctcgcata tcagaattga cggattttat
    19621 ggatttggga gagttaaaaa taggtacgac tgccttggct gaggaagact gggcagataa
    19681 ctggaagaaa tactatgagc cagctcgtat cactcatgat ttgaccatcg ttccctcttg
    19741 gacagactat gaggcgactg cgggagaaaa aattatcaag ctggatcctg gcatggcttt
    19801 tggtacggga acccacccaa ctaccaagat gagcattttt gccttggaac aggttcttcg
    19861 tggtggcgaa acggtgctag atgtgggaac tggttcaggg gttctctcta ttgccagctc
    19921 gcttctgggg gctaaagaaa ttttcgccta tgacctggat gatgtggcag ttcgtgtggc
    19981 tcaggaaaat attgagctca accctggaat ggaaaatatc catgtagcgg caggcgattt
    20041 gcttaaaggc gtggagattg aagcagatgt catcgtggca aacatcttgg cggatatcct
    20101 cattcatctg acagaggatg cttatcgctt ggttaaggat gaaggttacc tgataatgag
    20161 tggcattatc aaggataagt gggacatggt gcgcgagttg gctgaatcag ctggattttt
    20221 cctcgaaact cacatggttc aaggggaatg gaatgcctgt gtctttaaga aaaccaagga
    20281 tatctctggt gtgattggag gctagcatgc agcagtattt tgtaaaaggc agtgctatct
    20341 ctcctgtcac tatcgagaac aaggaaacca gtaagcatat gtttcaggtt atgcgcttga
    20401 aagaagagga tgaggttacc ttagtctttg atgatggcat caagcgcttg gcgcgcgtgc
    20461 tggatatgga aaatcgtcag tttgagttgg tccaagaatt aaatgacaat gtggaactac
    20521 cagttcaagt gaccatcgca tctggatttc ccaagggaga caagctggag ttcatcgctc
    20581 aaaaagtaac cgaactgggt gctagccaaa tctgggcctt tcctgcagac tggtcagttg
    20641 ccaagtggga tggcaagaaa ttgggtaaaa aagttgaaaa actagaaaaa attgcccttg
    20701 gagcagccga gcaaagcaag cgtaatattg taccaagtat taaacttttc gagaaaaaag
    20761 cagattttct aactcagctg gaccagtttg actctatcat agtagcctat gaagaatcag
    20821 gtaaagaagg agaagccgct gcgcttctgc aagcagtcac tggtcttgaa acaggagcca
    20881 aactgctctt tatctttggt ccagaaggcg gtctctcacc tgcagaaatc gaaagttttg
    20941 aagctaaggg agccgttttg gtaggcctag gtcctcgtat tttgcgagca gaaacagcac
    21001 cgctttacgc cttatcagcc cttagtgttt tagtagaatt agagaaataa gaggaagaaa
    21061 atggaacaaa aacaccgttc agaatttcca gagaaggaac tctgggactt aacagcccta
    21121 taccaagacc gtgaggattt cttgcgtgca atcgagaaag ctcgtgaaga catcaaccaa
    21181 tttagccgtg actacaaggg taatcttcat acttttgagg atttcgagaa ggcctttgcg
    21241 gaattggaac agatctacat tcagatgagc catattggca actatgcttt tatgcctcag
    21301 acgacggact atagcaatga cgaatttgcc aatattgccc aagctgggat ggaatttgaa
    21361 acagatgcca gcgtagcctt gaccttcttt gacgatgcct tggtggtagc agacgaggaa
    21421 gtcttggacc gtttgggtga attgcctcac ttgacggcag ctattcgtca ggccaaaatc
    21481 aaaaaagccc actatctagg ggctgatgtg gagaaggcct tgaccaatct cggtgaagtt
    21541 ttctacagtc cgcaggacat ttatactaag atgcgagctg gggattttga aatggctgac
    21601 tttgaagccc atggcaagac ctataaaaac agctttgtca cctatgagaa tttctaccaa
    21661 aaccatgagg atgctgaggt tcgtgagaaa tccttccgtt ccttctcaga gggacttcgt
    21721 aagcaccaaa atacggctgc agcagcctat ctggctcagg tcaagtctga aaaactcttg
    21781 gctgatatga agggatacga ctctgtattt gattatcttc tagctgaaca agaagtggac
    21841 cgtgtcatgt ttgaccgcca gattgacctc atcatgaagg actttgcacc agtcgctcag
    21901 agatacctca agcatgttgc caaggtaaat ggtcttgaaa agatgacctt tgcagactgg
    21961 aaattggact tggacagcgc cctgaatcct gaagtgacta ttgacgatgc ctatgatttg
    22021 gtcatgaagt cggtagaacc tttggggcaa gaatattgtc aggaagttgc tcgttaccaa
    22081 gaagagcgct gggtggactt tgctgctaac agtggcaagg attccggtgg ttatgcggcg
    22141 gacccatatc gcgtacaccc ttatgtactc atgagctgga caggccgttt gagcgatgtc
    22201 tataccttga ttcatgaaat cgggcattct ggtcaattca tcttttcaga caatcaccaa
    22261 agctatttca acgcccacat gtcgacctat tatgttgaag caccgtcaac cttcaatgaa
    22321 ttgctactca gtgattactt agagaaccag tctaatgacc cacgtcaaaa acgcttcgct
    22381 ctggctcatc gcttgacaga cacctacttc cataatttca tcacccacct cttggaagcc
    22441 gccttccagc gtaaggtgta tacattgatt gaagaagggg agacctttgg agcaagcaag
    22501 ctcaacagca ttatgaagga agttttgaca gatttttggg gcgatgccat tgaaatcgac
    22561 gacgatgcag ctttgacttg gatgcgccaa gctcactact atatgggctt gtatagttac
    22621 acttactctg ctggtcttgt catctcgaca gctggttacc ttcatcttaa aaactcagaa
    22681 actggagctg aagactggct caatctcctc aaatcaggtg gtagcaagac accacttgag
    22741 tcagccatga ttatcggtgc tgatatttca acagacaaac cactccgtga taccatccaa
    22801 ttcttgtctg acacagttga ccagattatc gcctacagtg ctgagttggg ggagtaaggg
    22861 gaatagaaaa attttctaga atgatgttta tgggcttgtt aagcgtcatt ctatttgtct
    22921 tagttgtagc tattttcaaa aatgtcgttg aaggtcgtga tgttaaattt gaacttactg
    22981 tagaactggt attgatagtt atttacgtca ttttatatca gattgtattt aattgagaat
    23041 tcaatattga gtcatttaag actgcctttt tgaacagttg ctagaaatgt agaggtattg
    23101 accatgtatc aagatttact aagaaaaata gcagaagaaa aaccaaatta taaccaggaa
    23161 gaaatccagt ggttgtttga tcatttggga aatccttctc cagaaattcg tgatgacctt
    23221 tcaaatcaag gcttgcacta tctttcaaaa gaaaaggata caacagattt ctcaagtcag
    23281 tatggttggg ttcatgcttt tgcacatgga gccgatttac tgacagaggt ggtttgtcat
    23341 ccagactttc ctataaacag aattcatgaa gtatttgaca tacttggcca actatttaaa
    23401 agaatgtcga ttcgctttac agatgatgag gattggcgtt tagcaagagt gatctatgaa
    23461 cctattttac aagggaagtt ggagcaagaa caagtagctt cttggataaa aactgttgat
    23521 tttccgatag aagaaaggga ggatttttac aaattttcca actttagatc ctgtctggtg
    23581 gaagtctatg tccaacttga ccagagaaat agtttacaag atgacctgaa agaagctatc
    23641 cagtcttttc aatactagag attagctaat agttctatga ttttcaaaaa atttccaatc
    23701 aattttcttg aaaccctttc ctacttttga tagactagta tctagttttt gaaaaaagga
    23761 gaaagaaaat gaaaaaattt gttgctgagt taatcggtac gttcatgctt gtgttcgttg
    23821 ggacaggagc tgttgttttt ggaaatggtc ttgatggcct tggtcacctt ggaatcgcct
    23881 ttgcctttgg tttggcaatc gtggtggcag cctactcaat cggaactgtt tcaggtgctc
    23941 acttgaaccc ggctgtttcg attgctatgt ttgtaaacaa acgtttgtca tcttcagaac
    24001 ttgtaaacta catccttggt caggttgttg gagctttcat cgcttctggc gcagtcttct
    24061 tcctcttggg taattcaggt atgtcaactg ctagtcttgg tgaaaatgcc ttggcaaacg
    24121 gtgtcactgt ctttggtggt ttcttgtttg aagtcatcgc aactttcttg tttgtcttgg
    24181 ttatcatgac tgtgacttca gaaagcaagg gcaatggcgc gattgctggt ttggtaatcg
    24241 gtttgtcatt gatggcgatg attcttgtcg gattgaagat tactggactt tcagtaaacc
    24301 cagctcgtag cttggcacca gctgtcttgg taggcggcgc agcccttcaa caagtttgga
    24361 ttttcatcct tgcaccaatc gctggtggag ttcttgcagc ccttgttgca aaaaatttcc
    24421 ttggaacaga agaataattg aaactcaaaa agccttgctc ctcatcttga ggaacagggc
    24481 tttttcgtat gatactcttc gaaaatctct tcaaaccacg tcagcttcac cttgccgtag
    24541 gtatggttac tgacttcgtc agttctatct gcaacctcaa aacagtgttt taagctgact
    24601 tcgtcagttc tatccacaac ctcaaaacag tgttttgatc tgacttcgtc agttctatcc
    24661 acaacctcaa aacagtgttt taagctgact tcgtcagttc tatctgcaac ctcaaaacag
    24721 tgttttaagc tgacttcgtc agtttcatct acaacttcaa aacactgctt tgagcaacct
    24781 gcggctaact tcctagtttg ctctttgatt ttcattgagt atgagtttag cggttgtcaa
    24841 ttttctctgg ataaaggtcg tgttggaaga ggcgttgttc tgccaagccc tcatacttag
    24901 ttccttgctt accgtagttg tagtaggggt cgattgaaat gccaccgcgc ggagtgaatt
    24961 ttccccagac ttctaaatag cgagggtcta gcaagttgac caagtctttc ccgatggtgt
    25021 tgatacagtt ttcgtggaaa tctccgtgat ttcggtagct aaatagatat agtttgaggg
    25081 attttgactc gacacagagc ttgtcaggaa tgtaggaaat atgaatcgtc gcaaagtctg
    25141 gttgagcagt gatttgtccc agcagagaca tatcgaggat atggtgacga atgccctgtt
    25201 ccttagcgat ttctctagca atttgaattt cgaggtgatg acgttggccg taggcaaagg
    25261 tgacagcttc gactgtttca tagtgttgca tggtccagaa aaggcaggtt gttgaatctt
    25321 gaccgccact aaagacgacc aaggctgatt gacgtttcat agtactcctt ccaaaatggg
    25381 aaatgttcag agcacgcaaa aagctcccat tagggagcta aaaaatacca aatcgaggtt
    25441 tttttagcga tggcatatcc caaacatcgt aatattctac ttatatagta aaatgaaata
    25501 agaacaggac aaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagtaga
    25561 ggtgtactat tctagtttca atatactata gtctagcata ttttttgaaa aatggcaaag
    25621 ggcaagaaaa aagagaccaa agaaagtact tggtctctcg tttgattagc tcaattcagc
    25681 aatgatggcc ttgatttgtt ctgctgtgtg aacacctgca acctgtttga caacttggcc
    25741 gtcttttttg aagagaagag ttggaataga catgattcca aaagcacgag ctgtgtttgg
    25801 attttcatca acgtccattt taacgatttt caagacatct tctgaaagtt cttcagacaa
    25861 tttgtccaag attggacctt gcatacgaca tggaccacac caagttgccc agaagtctac
    25921 taagaccaaa ccgtcttttg tttcttgttc gaatgttgca tctgtaattg cttttgccat
    25981 tgtatttctc ctttttttag ttatattggc ttaaatcttg tttcatgaga tagaagaaga
    26041 tatctccata agtcccatgg tagtccaaat tatgaccctt gtaagttaat ttttggacag
    26101 ggtagtagtc tgcgacgccg ataaggcaag cttgttgcga acgttcaaag tcttcataag
    26161 actcgaaagt cacagttctt tcgttcttgc tggcatctat ataggtaatt tcaatcatat
    26221 ttaaaactcc tttgtttaat gctaacttta ttttactcct tataaaagag aatgtcaaga
    26281 aaaatgattg cgcacgcaac tttttttaaa atcatcttaa atcaagaaat ccaaacctgc
    26341 ttccaagctt tcttcgacag tcttttgtag cgaggccagt gtcttttgcc catcatttgt
    26401 caggcagata aaactagagc gtctatcttg atggcaacac atgcgactga gtagaccgca
    26461 atttttagct tccaagcgag ccaccatcct agaaactgcg ctcgggctca gatgaagctt
    26521 atctggcagg tcaatctggc gtagagattt ttcttcagcc aagtccagat agtagagcag
    26581 gtagaactct ttcaaggtca gactttgctc gctctgttgg gcaatggtct cttccaagag
    26641 actttcaatt tctttctgac gccgattgaa gtcaaaccat ttttccaaat aggtcatagt
    26701 gtctcctttc tttttagagt cataaaatag aagaaagtcc attaacgggc agtctctgcg
    26761 tcacaagatg attgcgcatg caataattat actacttttc aagaatgctg gcaagctctg
    26821 ttttttagtg gttttatttt ttactgtcca tatttttggt aaaaatcaac ttttacttgg
    26881 atgaaggttt tggcttcacg taggagttga agaagggtgg cgcgggtttc aaactcttct
    26941 cttgtcttgg gcagactgcg gttccggaag acttccagat aactttcaat ttcatctagc
    27001 aaatcagaag caggattggt ctggctcagt tgaccagcaa tttttgaaaa gagctgcgct
    27061 aaaatcaggc tttcactggc ggcaaggtga caagtgttaa tctgttgggc catgtttctc
    27121 aggatacgac tttgtcgttg tctcatctca aagtagtgga tatggtagtc ggtctggtga
    27181 aagaggtggt cagagtgatc caaatagacc agtctgaggg cttctttcaa aagcgtgtct
    27241 aattctgcta ccagctgtgc tcggttgcgt ccgtctcctc tggataaata gtatttgaag
    27301 cgctggagga tatcttttaa cttttcttcc accagcgtgt ggtagtgctg gatttcctct
    27361 tctcgtgaag gcatatagag attaacaagc aaggcaaatc ctgtaccaat agcaaagaga
    27421 aggaattcat tgactagaag gtctggagag gttgactctt gaaccaagag atggctaacc
    27481 aaaacagtgc ttggtgtgat gccaatttcc cagcccatct tgtaggctaa aggaacgtag
    27541 aaggccagat agaggccgag actccagata tgaaatccgc tcaagtgaaa agctagaaca
    27601 ccgatagcca gagctagaag catagaaaaa agacgattgc gagccagttt taaagtactt
    27661 ctacgcgtat cagataggct caagagagcg ataattccag ccgaaactgc tgacgaaaga
    27721 ttgagaaaat aagcaagcag gcaggcaaga caggtagcta agatgagctt ggtcgtacgt
    27781 tggctaatag acataagaat ttcctaataa gttagaataa aagcgtaaaa gacaagacat
    27841 gagcaggctt gccttgatga gttatttttt acgggttgct gcgtattcgg caacggcggt
    27901 aaagaggaca tctgtagaag agttaagggc tgtttcacat gagtcttgga tgacaccaat
    27961 cacaaaacca accccaacaa tttgtatggc aatatcgtta gaaataccga aaaggctaca
    28021 agcaactggg ataagaagga gggaacctcc ggcaatacct gaagcatcac aggctgagat
    28081 agctgctacc acactgagga caaaggctgt ggcaaagtca acaggaattc caagagtgtt
    28141 aactgtaaca agggtcaaaa cgttaatggt aatcgctact ccagccatat tgatagtaga
    28201 accgagtggg atagaaacag aataggtatc tgggttgagt ccaaggtcat ggcagagttt
    28261 catgttgaca ggaatgttag tcgcagaact acgagtgaaa aaggctgtca caccgctgac
    28321 acggaggcag ttccaaacta gagggtaagg attgcgtctc ataaagaaga aggcaatcaa
    28381 agggttgacc acaggggcaa caaaaagcat agtcgttact aatagaacca ataaaatacc
    28441 gtagttggca aggcttccga ctcccttgtc agaaatggtt ttaaaaacaa gaccaaggat
    28501 tccaaatgga gccagattga tgatccattc gacaatttta gaagtcacgt cagcgatagt
    28561 ttttagcaat tctttactat ttttactggc ttctctcata gcgattccaa aaatgactgc
    28621 ccaagataag attctaatat agttagcagt aagcagggcg ttgactgggt tgtcaaccag
    28681 tttgagcaag aggttgctga ggacctgccc aatcccatct ggtggtgcaa tttcagtatt
    28741 ggcactattt agggtaattt caatagggac gatgaaactt gctagtacag ctacaagagc
    28801 agcggcgaaa gtccctatca taggatatac aagaaaacaa cagttttcat attgctatct
    28861 tgtccctttt gatgttggaa agggcattgg caacgagggc aaagactagg ataggagcaa
    28921 cagcttttag acctccaacg aataaatccc cgagtagccc aatccctgag agattaggaa
    28981 gggtcagtcc taggattccc cacaaagcat accaatcaag atacgcttga caaggcttgc
    29041 cttattccaa gcatgaatga ttcttttcat aataatctcc tttttgtgta gtgattatga
    29101 ttatagtata aatgatagac aaaatcaaga attttctgtc tattttttga atatttatgg
    29161 agaatgagac tgatgaaaat atggtataat gaaataaagg agttttatat gcaaaaattt
    29221 attcaggctt atattgaaaa gctagatgtg acaaccatta tcgagaatat tctaaccaag
    29281 gtcatttctc ttttactgct tttgattgta ttttatattg ctaaaaaaat gcttcatacc
    29341 atggtgcaga gaattgtcaa accttctcta aaaatgtctc gtcatgatgt cggacgccaa
    29401 aaaaccatct cacgtttact agaaaatgtg tttaattata cgctatattt ctttttactc
    29461 tactgcattt tgtcgatttt aggtttgcca gtttctagtt tgctggctgg agctggtatt
    29521 gctggggtag cgattggtat gggagcccaa ggctttctgt ctgatgtcat caatggcttt
    29581 ttcatcctct ttgaacgtca actggatgtg ggagatgagg tcgttctgac aaatggaccg
    29641 attactgtat cgggtaaggt tgtcagtgtg ggaattcgta cgacacagct tcgtagcgag
    29701 gagcaagccc ttcactttgt ccctaaccga aatatcacag ttgttagcaa tttctcacgc
    29761 acagactaga cctgttattt taagtaattt gtggtacaat agagggagtt taataaggag
    29821 aaaagatggt tttagaaaag cagttgggca atggttgtac ctggatagac ctagacctag
    29881 gaaagttgaa taaactagaa gacctttctg aaatttacgg tttggacaag gaaaccattg
    29941 aatacgcact ggatagaaac gagcgcgccc acatggatta ccaccgtgaa agtgggacgg
    30001 ttacctttat ctataatgtc ctagacgtaa aaaaggacaa ggcctactat gagacttttc
    30061 ccatgacctt tattgtcgag catcgtcgcc tgattaccat tagtaatacc aagaacgcct
    30121 atgtcattga acagatgact cgttatctgg agagccatga cacgctttcg atttataagt
    30181 ttctctttgc cagtctggaa attatcagca atgcctacta tcctgtcatt gagcagatgg
    30241 acaagagtag ggatgaggtc aatgacctct tgcgccagcg aactaccaag aaaaacctct
    30301 ttgccctgtc tgatttggag actggtatgg tttatctgac ggcagctgcc aaacaaaatc
    30361 ggattttgtt agagcatatt caaggtcatg ccttgtatcg tagttttgat gagattgaga
    30421 gagaacagtt tgatgatgcc atgattgagg ctcatcagct ggtatccatg acagacctaa
    30481 tctctcagat tttacagcag ctttcagcct cttacaacaa tattctaaac aataatctga
    30541 atgacaattt gacaaccttg actatcattt cagtcttgct agctgttttg gcagtcgtga
    30601 caggcttttt cggaatgaat gttcccttac ctttaacaga tgagccccat gcttggctct
    30661 atatcagttt ggctagtgca ggtttgtgga ttgttttatc cttgttacta aggaaaattg
    30721 cgaaaaaaag ttaagaaaag gagccagaat ggcgattgaa aattatatac cagattttgc
    30781 tgtggaagca gtctatgatc tgacagtccc aagcctgcag gcgcagggaa tcaaggctgt
    30841 tttggtcgat ttggataata ccctcattgc ttggaacaac cctgatggaa cgccagagat
    30901 gaagcaatgg ctacatgacc ttcgggacgc gggtattggc attatcgtag tgtcaaataa
    30961 caccaaaaaa cgcgttcaac gagcagttga gaaatttggg attgattacg tttactgggc
    31021 cttgaagccc ttcacatttg gtattgaccg tgctatgaag gaattccact atgacaaaaa
    31081 ggaagtggtc atggttggcg accagctcat gacagatata cgagcagccc accgtgcagg
    31141 gattcggtca attttagtca aacccttggt ccaacatgac tcaatcaaaa cgcagattaa
    31201 ccgaactcgt gagcgtcgtg ttatgagaaa aatcactgaa aagtacggac cgattacata
    31261 taaaaaagga atttaactat ggaagaaatt ctctgtattg gttgtggagc aaccattcag
    31321 acgacagata aagctggtct tggttttacc ccccagtcgg cacttgaaaa aggtttggag
    31381 actggcgaag tctattgcca acgctgtttc cgtctccgcc actacaatga aatcacagat
    31441 gtccagttga cgaacgatga tttcctcaag ctcttgcacg aggtgggaga cagtgatgcc
    31501 ttagtggtca atgtcattga tatctttgat tttaatggat ctgtcatccc aggtttacca
    31561 cgtttcgtct cgggcaatga tgtcctcttg gtaggaaata aaaaagatat ccttcctaag
    31621 tcagttaagt ctggtaagat tagccagtgg ctcatgaaac gtgcccatga agaaggtctt
    31681 cgtccagtcg atgtggtcct aacttcagca caaaataaac atgccattaa ggaagtcatt
    31741 gacaagattg aacactaccg taagggccgc gatgtctatg tggtcggtgt gaccaacgtt
    31801 ggaaaatcaa ctctaatcaa tgctattatc caagaaatca cgggtgatca gaatgtcatc
    31861 actacttcac gcttcccagg tacaaccttg gacaaaatag agattccgct tgacgacgga
    31921 tcttatattt acgatacgcc gggaattatc caccgccacc agatggctca ctacttgacg
    31981 gccaaaaacc tcaagtatgt cagtcctaaa aaggaaatca agcctaagac ctatcagctt
    32041 aatcctgagc aaaccctatt tttaggtggt ttgggacgct ttgactttat agcaggagaa
    32101 aagcaaggat ttactgcttt ctttgataat gaactcaaac tccatcgtag caagcttgaa
    32161 ggagctagtg ctttctacga taagcacctg ggaactcttc tgacaccacc aaatagcaag
    32221 gaaaaagaag atttcccaag gctagtccag catgtcttta ccattaaaga taagacagac
    32281 ctagtcatct caggcctagg ctggattcgt gtaacaggca tagcaaaagt cgccgtctgg
    32341 gcaccagaag gcgtcgccgt cgtcacacga aaagcaatta tttaaaacaa aatcgctgag
    32401 cgaacaaagt gagctcatat agcgatagtt attgccgtgg tgtgattgcc aatctgtaga
    32461 ttggcaaggg gcacaattga gaccaaggct caattgtgag gtcaggaaat ccatttttca
    32521 aagatgaaat ctttggaaaa ttagttccga ccgtccctca ccacctaaaa taactatcaa
    32581 aaaacaagga agaaaattat gtcattaaca tcaaaacaac gtgccttcct caacagccag
    32641 gcacacaccc tcaaacctat catccaaatc gggaaaaatg gactcaacga ccaaatcaaa
    32701 accagcgtcc gtcaagctct tgatgcgcgt gaattaatca aggttactct cttacaaaac
    32761 acagatgaaa acatccacga agtagctgaa attttggaag aagaaatcgg tgtggataca
    32821 gtccaaaaaa taggacgcat cttgattttg tttaagcaat ctagcaagaa agaaaatcgc
    32881 aagatttcta agaaagtcaa agaaatctaa gaccgaaact ccaaataact gtttttatag
    32941 agaaataaag gggactagcc tatgacaatc gaactattga ctccctttac caaggtagag
    33001 ttggagccag aaatcaagga gaaaaaacgc aaacaagttg ggattttagg ggggaatttt
    33061 aaccctgttc acaatgccca tctcattgtt gcggatcaag tacggcaaca gttgggactg
    33121 gatcaagttc ttctcatgcc tgaataccaa cctcctcacg ttgataaaaa ggaaaccatc
    33181 cctgaacacc atcgtctcaa gatgcttgag ttggcaattg agggaattga cggcctagtc
    33241 attgaaacca ttgagttgga gcgcaagggt atttcctaca cctacgacac catgaagatt
    33301 ttgacagaga agaatccaga tacggattat tactttatca tcggtgccga catggttgac
    33361 tatctgccta agtggtaccg aattgatgaa ctggttgaca tggttcagtt tgtgggggtt
    33421 cagcgtccac gctacaaggt agggacttcc tatccagtta tctgggtgga cgtaccgctc
    33481 atggatatct cgtccagcat ggtgcgggac ttccttgccc aaggtcggaa acccaacttt
    33541 ctcctacctc agccagtgct agactacatc gagaaggagg ggctctactg atgtcctatc
    33601 aagactatat caactgctcc cgtgaggcct tgttggaaaa aatggcagag tttctacctg
    33661 agaaacgtct aacccattgt ctaggtgtgg agcgtgccgc tatggaatta gctcagcgct
    33721 ttggtgtaga tgttgagaaa gcaagtctag caggtcttct tcatgactat gctaaaaagt
    33781 tgtcaaatca ggaatttcta gccttgattg accgttacca gctagaccct gacctcaaaa
    33841 actggggcaa taatgtctgg catggtatgg tcggaattta caaaattcag gaagatttgg
    33901 atttgcatga ttcagaaatc ctgcgagcca ttgaagtcca tacagtcggt gctggtcaaa
    33961 tgacagacct agataaggtc atctacgtcg cagactatat cgagcacaat cgagcctttc
    34021 ctggagtaga tgtggcgcgt gagattgcaa atctatcgct caataaggcg gtggcctacg
    34081 aaacagctcg taccgtggag tatctagctc atcagggatt ccccatctat ccccaaaccc
    34141 ttgaaaccta taacgccttt gtgcactatt tgaaagagaa ctaaatgaag acggctttta
    34201 taatcattga tgttcagaat gttttagtag aaactgggtt ccagacaaaa agtctattgg
    34261 gaaaaatttc ttatttacaa aaccaggcta gaagcaagaa tattgaaatt atctatgttc
    34321 aacatattga gaactctgaa gctcaaacat cagaagattg gcagttatct gcgcttttaa
    34381 atcgaaaacc tgctgaaaag gtctttcaga agaagtataa cagtattttc aaagaaactg
    34441 gcttaaaaga atacttggat aagcagggga ttgaaaaatt agttttatgt ggtatgcaga
    34501 cagaatattg tgtggatacc tctgtcaagg ttgcctttga atatggctat cagcttattg
    34561 ttccagaagg tgctgtcaca acctttgatg gggatgacat tccagcagaa acgattaatg
    34621 aattttatga ggacatttgg gaggagcgct ttgcagatgt tctagattac aaacatattt
    34681 tctaaaaaga ggattaaatg aacgaaaaag aattactaga actagtcgtg aaagcggctg
    34741 atgagaaacg tgcggaggat atcctcgcac ttgatgtaca agatttgact agtgtgacgg
    34801 actactttgt catcactagc tcaatgaata gccgtcagtt ggacgctatc gcagctaata
    34861 tccgtgaaaa agtagctcaa gcaggcttta aaggtagcca tgtcgaaggc gatgcagctg
    34921 gaggctgggt cttactggac cttggtgctg ttgtcgtgca tatcttttca gaagaaatgc
    34981 gtgcccatta taatctagag aagctatggc atgaggcgaa ttcagtagat atttcagaag
    35041 ctcttgctta gaagatgaac tcagttgtag tcaactgggt ttctttgctt attttagaaa
    35101 aattgataga aaggtaaagg gctagtggtg tttaccatgg agctcttagt atcatgatta
    35161 tggcgactta tgaaaccttt gcggcggtct atgatgcggt catggacgat agtttatacg
    35221 acaaatggac gaatttttct ctgcgtcatt tgcctaagac caaggagaga aagaaactct
    35281 tggaattggc ttgtgggaca ggaattcaat cagtgcgctt ttctcaggct ggttttgatg
    35341 tgactggact tgacttgagt gcggatatgt tgaagattgc ggagaagaga gcaacttcag
    35401 ccaagcaaaa gattgctttt atagaaggta atatgctgaa tttgtccaag gcagggaaat
    35461 acgattttgt cacgtgttat tcggactcta tctgctatat gcaggatgag gtggaagtag
    35521 gggacgtctt taaggacgtg tacaatgcgc tgaatgaaga gggagttttc atctttgacg
    35581 tgaactcgac ctaccagaca gatgaagtat tccctggcta ttcctaccat gaaaatgcgg
    35641 aagattttgc catgctttgg gatacatatg aggacgaagt tcctcactcc atcgtgcatg
    35701 agctgacttt ctttatcaag gaggctgacg gttcctttag tcgccacgat gaagtacatg
    35761 aggagaggac ctatgagatc ttgacctatg atatcttgct ggaacaggct ggatttaagt
    35821 ccttcaaact ctatgcagac tttgaggata aggagccaac agaaactagc acccgttggt
    35881 tttttgtggc gcagaagtag gagattagca tgaccatcac aggtattatc gcggagttca
    35941 atccttttca taatggccat aaatacctgc tggatcaggc agagggactg aaaattgttg
    36001 ccatgtcagg gaatttcatg cagcgtggag agcctgctat tgtggataag tggacaaggg
    36061 cccagatggc gctggaaaat ggcgcagact tggtagtgga attgcccttt ttagtcagtg
    36121 ttcaggcggc agattttttc ggtcaaggat ctgtggatat cttggatcgc ttgggcatag
    36181 atagcctcgc ttttgggaca gaagaagttc tagattatca aaaaatcgct gacttataca
    36241 cagagaaagg tgctgagatg gagaaatttg tgaaaaatct gcctgattcc ctttcctatc
    36301 cccagaaaac ccaagctatg tggaaggaat ttgctggtct tgatttttca ggtaataccc
    36361 ccaatcatgt tcttgctctg gcctatgcca aggcggttgc aggacggaat atcaagctgc
    36421 atccgattca gcgtcagggg gcaggttacc attctgtgaa taaagatgtg gactttgcct
    36481 cggcgacagc cctccgtcaa catcagaagg accaagattt cttagaacgt tttatgcctt
    36541 ctgttgccct atttgagcag gccagtaagg tgatctggga agactatttt cccttgctcc
    36601 gctatcaaat cttgtcaaat cccgacctaa ccaccatcta tcaggtcaat caagaaatgg
    36661 ctgtgcgcat taaagaagct attaaaacag cccagtctgt ggaagaattg gtcgagttag
    36721 tgactaccaa acgttacacc aaggcgcgtg tcagacgcct attgacctat attttgatgc
    36781 aggctagaga aagtgacttg ccagaagcca ttcatgtcct tggatttact gaaaaaggta
    36841 ggcaacatct caagtctttg aaaggtcagg tcagtctagt cagccgaatt ggcaaagaac
    36901 cttgggatgc tatgactcaa aaggttgacc agatttacca actaggaaag ccaagtatag
    36961 cagagcaaaa ttttggcaga gtgccaatta gaatagaaac aaactaagtc tactgaaagg
    37021 taggcttttt gagatttttt acgaataata ctcttcgaaa atcaaattca aatcgcgtca
    37081 acgtcgcctt gccgtactca agtacagcct gcggctagtt tcctagtttg ctctttgatt
    37141 ttcattgagt ataaatagat agaaaagaaa atcttgtaca agttcctgac aatttctttc
    37201 ttttcgtgta taatagtgga aaagagctaa aacgaggtat ggttatggaa gcagtccttt
    37261 actcaacatt ccgaaatcat ttaaaggact acatgaagaa ggtaaatgat gaatttgagc
    37321 ctttgacggt ggtcaataaa aatccagatg aggacattgt agttctttca aagagcgaat
    37381 gggacagtat tcaggaaacc ctgagaatcg cccaaaataa ggagttatca gacaaggttt
    37441 tacgaggaat ggctcaagtc cgtgctggaa gcactcaggt ccatgtgatt gaggagtgat
    37501 gaatgctact caagtttaca gaagatgcct gggcagatta ttgctactgg caaaaccaag
    37561 ataaaaaaac actaaaaaga atcaataaat taatcaagga tattcaacgc gatccattta
    37621 caggaatagg aaaaccagag ccactcaaat atgattacca aggagcctgg tcacggcgta
    37681 ttgatgcaga aaatcgcttg atttatatga tggatggaga tagcgtggct ttcttgtcct
    37741 ttaaagatca ttactaagtc tactgtaaag taggcttttt ctcaagtctc tactaaacta
    37801 ctatttctaa acaacaagtt tatttttgca aatgtgttcc aaattcccca aaacatattc
    37861 tattttaggt ttgtgaaaat cactttttta tggtagaatg taaaagaatg tatgtcattc
    37921 ggaataacaa taaaatgagg taaaaacatg gaaatcatgt cgcttgcgat tgctgttttt
    37981 gccgtcatca ttggtttagt cattggatat gtcagcatct cagctaagat gaaatcatct
    38041 caggaagctg cagagttgat gcttttaaat gctgaacaag aagcaactaa tttacgtgga
    38101 caagctgagc gtgaagcgga tttacttgtt aatgaagcca aacgtgaaag caagtctctt
    38161 aaaaaagaag cactattgga ggccaaagaa gaagccagaa aataccgtga agaagtggac
    38221 gctgaattca aatcagaacg tcaagaactc aaacaaatcg aaagtcgttt gacagagaga
    38281 gctactagcc ttgaccgtaa ggacgacaat ttgacgagta aagaacaaac acttgaacaa
    38341 aaagaacaaa gtatttctga tagagcgaaa aaccttgatg cgcgtgaaga gcaattagag
    38401 gaagtcgaaa gacaaaaaga agcagaacta gagcgtattg gtgctctgtc tcaggcagaa
    38461 gcacgagata ttatcttggc tcagacagag gaaaacttga ccagggagat tgccagtcgc
    38521 attcgcgaag ctgagcaaga ggtcaaggaa cgttctgaca aaatggccaa ggacatcttg
    38581 gttcaagcta tgcaacgtat cgctggtgaa tatgtagcgg agtcaacaaa ctcaacggtt
    38641 catctgccag acgatactat gaagggacgc attattggtc gtgaaggtcg taacattcgt
    38701 acctttgaaa gtttgacagg ggtcgatgtg attatcgacg atacaccaga agtggtgacc
    38761 ttgtcaggat ttgatccgat tcgtcgtgag attgcccgta tgactatgga aatgttgctc
    38821 aaagatggtc gtatacatcc agctcgtatc gaagagttgg ttgagaaaaa ccgtcaagag
    38881 attgacaata agattcgtga atacggtgag gctgctgcct atgaaattgg tgcgccaaac
    38941 cttcatccag acttgatgaa gattatggga cgtttgcagt tccgtacttc atatggacaa
    39001 aatgttttgc gccattcgat tgaggttgct aagttggctg gtatcatggc gagcgaactt
    39061 ggtgaaaatg cggctcttgc ccgtcgtgct ggattccttc acgatatcgg gaaagccatt
    39121 gaccatgagg ttgaaggtag ccacgttgaa atcggtatgg aattggcccg taagtacaag
    39181 gaacccccag ttgtggtgaa tacgattgct agtcaccacg gagatgttga agctgagagc
    39241 gtgatagcag ttatcgtcgc tgcagcagat gccttgagcg cagcccgtcc aggtgctcgt
    39301 agtgagtctc ttgaaagcta catcaagcgt ctccatgatt tggaagaaat tgctaacggc
    39361 tttgaaggag tgcaaactag ctttgccctt caagcaggac gtgaaattcg tatcatggtc
    39421 aatccaggaa aaatcaagga cgacaaagtc acaatcttgg ctcacaaagt tcgtaagaaa
    39481 attgaaaaca atctcgatta tccaggaaat atcaaggtaa ccgtgattcg cgagcttcgt
    39541 gcagtagatt atgctaaata aataagaaag agcagttgaa aaattactgc ttttttgtta
    39601 cactagatag aaagactgta aaggataatc tggctttttg ccattattct agagaaatgt
    39661 tatttcacag attgactaaa aggagacaca atggcagacc gaggcttact aatcgttttt
    39721 tctggtcctt caggggttgg aaaaggaacg gttagaagag agatttttga gagttctgaa
    39781 aaccaatttc aatattctgt atcgatgacg acacgcgcac aacgtcctgg agaagtggac
    39841 ggtgttgact atttcttccg tactcgtgaa gaatttgaag agctgattcg tcaaggacag
    39901 atgttggaat acgcagaata tgtcggcaac tactatggaa ctcctctgac ctatgtcaat
    39961 gaaaccttgg acaagggaat cgatgttttc cttgaaattg aagttcaggg tgctcttcag
    40021 gtcaagaaaa aggttccaga tgctgtcttt atcttcctga caccaccaga tttggatgaa
    40081 ttgcaagatc gcttggtagg tcgtggaaca gatagtgcag aagtgattgc ccaacgaatc
    40141 gaaaaggcca aggaagaaat tgccctcatg cgtgagtatg attatgcgat tgtcaacgat
    40201 caggtgcccc tagctgctga acgtgtcaaa tgtgtgattg aagcagaaca cttctgtgtg
    40261 gatcgtgtca ttggtcacta tcaggagatg ttaccaaaat ctccaactac ccgataaaat
    40321 ttagaaaata ggtacaagca aatgatgtta aaaccctcta ttgatacctt gctcgacaag
    40381 gttccttcaa aatattcact cgtaatcttg gaagcaaaac gtgcccacga attggaagca
    40441 ggtgccccag caactcaagg ttttaagtct gaaaaatcaa ctcttcgcgc tttagaagaa
    40501 atcgaatcag gaaacgttac aattcaccca gatccagaag gaaaacgtga agcagtgcgt
    40561 cgccgtatcg aagaagaaaa acgccgcaaa gaagaagaag aaaagaaaat caaagagcaa
    40621 attgctaaag aaaaagaaga tggtgaaaaa atttaaggtt ggggggactc aatcttattt
    40681 tttctattgc aagaatgtac tgacaaggag gaggtgagac gatggcccta gctaagatta
    40741 tcgtagatgt gcccttgatg cagacggacc agccctatag ttacaggatt ccggaggaat
    40801 ttgagggaat gctggaagtt gggatgcggg ttcatgtgcc ttttggtaag gggaatcgcc
    40861 tgattcaagg gattgttctt ggtttggagt cccaatcaga tggagaagag atggagcaag
    40921 atttaaaaga tattgcagag gtgctggatt tttctcctgt tctcacgcca gaacaactct
    40981 ggctggctga ggagttacgc aaatctgtct tctcctacaa aatttctatc ctcaaggcta
    41041 tgcttccagg atttctgaat tctagctatg acaagattct ctatcctctg gaaggcttga
    41101 gtcaggaaga acgagtgcgc ctgtttggtt cagaagattc gctagccttt tcttcactag
    41161 accttgccaa gcaagctgaa atgatgcgtt tgactagaaa aggcctgctt agtctggaat
    41221 atcaggcagt cgatcaaaag aaggtcaaga cccagtcttg gtatgaggtt gaccatgctc
    41281 aattagaagg tgttgagatt tctacacgtg ccaagaaaaa gttggaactg agagattatc
    41341 tgctgtctca tccagagagc gcttccttgg ctagcttgtt agagtcctac tcgcgagagc
    41401 aagtcaactt ctttgtggat caaggtgctg ttaccatagt ccaaaaggaa gttcaacgct
    41461 cggctgctta ttttgaagga attgaagcaa gtagaccttt ggagttaaat ccagaacaaa
    41521 gacaggcgcg tgatgcggtt gtgagttcta ttggcagttc tcaacctccc tttctacttc
    41581 aagggattac aggaagtggg aagaccgagg tttacttgca gattatccaa ggtgccctgg
    41641 ataagggcaa gacagcgatt ttgctggtac ctgagatttc cttgactcct cagatgaccg
    41701 agcgttttat agcacgtttt ggggacaagg tagccattct tcactcagga ttatccaatg
    41761 gtgaaaagta tgatgaatgg cgcaaggtgg agcgtggcga tgcccaagtt gttgttggtg
    41821 ccagatctgc tatctttgct cctctgaaaa atctgggtgt catgattatt gatgaagagc
    41881 atgaagcggc ttataagcag gacagcaatc cccgttacca tgccagagag gtagctattt
    41941 tacgggctca gtataatcaa gcaactctgg tacttggatc tgcaacgccg agcttagaga
    42001 gccgggcacg tgctggcaaa ggcgtctatc aacacttacg tctaacccaa cgtgccaatc
    42061 ctttggctac aatccctgag gttcaagtga ttgactttcg agactatatc ggacaaaatg
    42121 agacgtcaaa ctttacgcct cctttgctag aggctatcca agaccgtctg gttaaaaaag
    42181 agcaggtggt tctcatgctc aatcgccgtg gttattctag ctttgtcatg tgtcgggagt
    42241 gtgggacggt ggatacttgt cccaactgcg atatttctct gaccttgcat atggatacca
    42301 agactatgaa ctgccattat tgtggtttct cgaaggatat tcctcaggtc tgtcctaact
    42361 gtaagagccg cagtattcgt tactatggga cgggaactca gaaggcttat gatgagctag
    42421 cagaactctt tccccaagct cgcattttga ggatggatgt ggatacgact cgaaagaaag
    42481 gcagtcacca agccttgctt gaccagtttg ggcgagggga agcggatatt ttacttggta
    42541 ctcagatgat tgcaaagggt ttggattttc ccaatgttac cctagtcgga gttctaaatg
    42601 cggatacggc cttgaatctg cctgatttcc gttcttctga gagaaccttc cagctcttga
    42661 ctcaggtggc aggtcgagca ggtcgggctg aaaaagcagg tcaagtcttg atacagtcct
    42721 acaattcgca gcactatgct attcgatttg ccaaggatca agattacgaa ggcttttatg
    42781 cctatgaaat gggaatcaga cgacaactcg gctatccacc ttactatttc acgattggta
    42841 ttaccctttc tcacaagaaa gaagaagagg ttttcaaacg tgcctatgaa gtcatgaaca
    42901 ttttgcggtc aggcttgtca gagaccagtc ccattctggg gccaacgcca aaaccgattg
    42961 cccgtaccca caacctctat cattaccaga ttttaattaa ataccgttta gaagatgagc
    43021 tggggccgac cctcaaccag gtcttggcct tgactcaaga acgggaaaat agtgagctcc
    43081 gtctcagcat tgaccatgag ccgcagcaat ttttataaga aggagaagat atgacaaaac
    43141 taatctttat ggggaccccc gacttttcag caacagtctt aaaaggactt ttgacagatg
    43201 accgttacga aattctagcc gttgtgaccc agccagaccg tgctgttggt cgtaaaaaag
    43261 ttatccaaga aaccccagtc aagcaggctg ccaaggaagc aggactatct atctaccaac
    43321 ctgaaaaatt atctggaagt ccagagatgg aagaacttat gaagctagga gcagatggaa
    43381 ttgtgactgc tgcttttggg cagtttctcc caagcaaact ccttgatagc atggactttg
    43441 ctgtcaacgt tcatgcctcc ctccttccta gacaccgtgg tggtgcgcct atccattatg
    43501 ccttgattca aggggatgag gaagctggtg tgaccatcat ggaaatggtt aaggaaatgg
    43561 atgcaggaga tatgatttct cgtcgcagca ttccgatcac agatgaggac aatgttggca
    43621 ccttgtttga aaaattggcg ctagttggtc gtgatttgct tttggacact ctgcctgcct
    43681 atattgctgg tgatatcaaa cctgaaccgc aggatacgag tcaggttacc ttctctccaa
    43741 atataaagcc agaggaagaa aaactggact ggaacaaaac caatcgtcaa ctctttaacc
    43801 aaattcgtgg aatgaacccc tggcctgttg cccatacttt ccttaagggc gaccgcttta
    43861 agatttatga agccctacca gtagaaggtc agggaaatcc aggtgagatt ctctctatcg
    43921 gcaagaaaga attgattgtc gcaacggctg aaggggctct atccctcaaa caagtgcagc
    43981 cagctggtaa gcctaagatg gacattgctt ccttcctcaa cggagttgga cgtacattga
    44041 ctgtaggaga acgatttggt gactaaagta gaaacggcta gaagtttagc tctagcagtg
    44101 ctagaggatg tttttgtgaa ccaagcatac tcaaatatcg ccttaaataa gcatctaaag
    44161 gggagtcaac ttttggcagc agacaagggc ttagtgaccg agctggtcta tggaacggta
    44221 gcccgtaaac tgactctgga atggtaccta tcccacttta tcgaagacag agaccagtta
    44281 gacagctggc tctatgtcct tcttctcatg agtgcctacc aactccgcta tttggacaag
    44341 attccagatc atgctgtggt caatgaagca gtggaattag ccaaactccg taaaaaaggc
    44401 agtgaaaaat tggtcaatgc cctccttcgc cgtatcttgc gtgaaggctg gccagatatt
    44461 gctagcatca agcgaaaaaa caaacgtgac tccattgcct attctctccc agtttggcta
    44521 gttgccaaac tcaaggaaga atacggagag gagagagcaa aagccatctt tgaaagcctg
    44581 ttagtgcgaa acaaagccag tattcgtgta acagacctaa gtcgaaaaga ggaaatccaa
    44641 gccttgttgg aggcgaatga ttccctttta gcaaccactg gtctggttaa ggagcagggg
    44701 cattttgcag ggcataattt gtttgcggat ggagccatta ccatccaaga cgagtccagt
    44761 cagctggttg ctccgacgct tgatttacaa ggtgatgagc gagtgcttga tgcctgtgcg
    44821 gctccaggtg ggaaaacagc ccatatagcc tcttatctta cgacaggtca ggttactgct
    44881 ctggacttgt acgaccacaa gttggattta attcaagaaa atgcccaacg tctgggagtt
    44941 gaagatcggg ttcaaactca aaaattggat gccagaaagg tgcatgagtt ttttgaccag
    45001 gattcctttg ataagatttt ggtggatgct ccttgttcag gaatcggtct tttgcgccga
    45061 aaaccagata tcaaatacaa taaagaaacg gcagatttcg cgtccttgca ggaaattcag
    45121 ttagaaatat taggtagtgt ttgtcaaata ctaggcaaag gtggtataat aacttatagc
    45181 acctgcacta tcgtctcaga ggagaatttt caagtcgtta aggccttttt agagagtcat
    45241 cccgagttcg agcaggtaaa actagaacat gaatgtaagg atatcatgaa agacggctgt
    45301 atcctcatta cacctgaatt gtatggaagt gatggattct tcatcagtca atttcgcaag
    45361 atatcggatt aggaaggaac tgacacatgg aaatttcatt attaacagat gttggtcaga
    45421 aacgaacaaa taaccaagac tatgtcaacc actatgtcaa tagagctgga cgtaccatga
    45481 ttattttagc tgatgggatg ggaggtcatc gtgcagggaa tatcgctagt gaaatggcgg
    45541 tcacagacct gggtgtagct tgggttgata cccagatcga tacagtcaat gaagtgcgtg
    45601 aatggttcgc ccattaccta gaaattgaaa atcaaaagat tcaccagctt ggtcaggatg
    45661 aagcttacag aggcatggga actactttgg aagtccttgc tattattgat aatcaggcta
    45721 tctatgctca tattggtgat tcgcgtatcg gcttgattcg tggagaagaa taccatcagt
    45781 tgacgagcga tcattccttg gttaatgaat tgctcaaggc tggtcaattg acaccagaag
    45841 aggcagaagc tcatccgcaa aaaaatatta tcacccagtc tattgggcaa aaagatgaaa
    45901 ttcagcctga ttttgggaca gttatccttg agtcaggtga ctatctcttg ctcaatagtg
    45961 acggcttgac caacatgatt tcaggcagtg agattcgtga tattgtaacc agtgatattc
    46021 ctttagcaga taaaacggag acacttgttc gttttgctaa caatgcagga ggtttagaca
    46081 acattacggt tgcccttgtt tctatgaacg aggaggatgc agaatgatcc aaatcggcaa
    46141 gatttttgcc ggacgctatc ggattgtcaa acagattggt cgaggaggca tggcggatgt
    46201 ctacctagcc aaagacttaa tcttagatgg ggaagaagtg gcagtgaagg ttctgaggac
    46261 caactaccag acggacccga tagctgtagc tcgttttcag cgtgaagcga gagctatggc
    46321 agatctagac catcctcata tcgttcggat aacagatatt ggcgaggaag acggtcaaca
    46381 gtatcttgca atggagtatg ttgctggact agacctcaaa cgctatatca aggaacatta
    46441 tcctctttct aatgaagaag cagtccgtat catgggacaa attctcttgg ctatgcgctt
    46501 ggcccatact cgaggaattg ttcacaggga cttgaaacct caaaatatcc ttttgacacc
    46561 agatgggacg gccaaggtca cagactttgg gattgctgta gcctttgcag agacaagtct
    46621 gacccagact aactcgatgt tgggctcagt tcattacttg tcaccagagc aggcgcgtgg
    46681 ttcgaaggcg actgtgcaga gtgatatcta tgccatgggg attattttct atgagatgtt
    46741 gacaggccat atcccttatg acggggatag cgcggtgacc attgccctcc agcatttcca
    46801 gaaacccctg ccgtccgtta ttgcagaaaa tccatctgta cctcaggctt tagaaaatgt
    46861 tattatcaag gcaactgcta aaaagttgac caatcgctac cgctcggttt cagagatgta
    46921 tgtggacttg tctagtagct tgtcctacaa tcgtagaaat gaaagtaagt taatctttga
    46981 tgaaacgagc aaggcagata ccaagacctt gccgaaggtt tctcagagta ccttgacatc
    47041 tattcctaag gttcaagcgc agacagaaca caaatcaatc aaaaacccaa gccaggctgt
    47101 gacagaggaa acttaccaac cacaagcacc gaaaaaacat agatttaaga tgcgttacct
    47161 gattttgttg gccagccttg tattggtggc agcttctctt atttggatac tatccagaac
    47221 tcctgcaacc attgccattc cagatgtggc aggtcagaca gttgcagagg ccaaggcaac
    47281 gctcaaaaaa gccaattttg agattggtga ggagaagaca gaggctagtg aaaaggtgga
    47341 agaagggcgg attatccgta cagatcctgg cgctggaact ggtcgaaaag aaggaacgaa
    47401 aatcaatctg gttgtctcat caggcaaaca atccttccaa attagtaatt atgtcggccg
    47461 gaaatcttct gatgttatcg cggaattaaa agagaaaaaa gttccagata atttgattaa
    47521 aattgaggaa gaagagtcga atgagagtga ggctggaacg gtcctgaagc aaagtctacc
    47581 agaaggtacg acctatgact tgagcaaggc aactcaaatt gttttgacag tagctaaaaa
    47641 agctacgacg attcaattag ggaactatat tggacggaac tctacagaag taatctcaga
    47701 actcaagcag aagaaggttc ctgagaattt gattaagata gaggaagaag agtccagcga
    47761 aagcgaacca ggaacgatta tgaaacaaag tccaggtgcc ggaacgactt atgatgtgag
    47821 taaacctact caaattgtct tgacagtagc taaaaaagtt acaagtgttg ccatgccgag
    47881 ttacattggt tccagcttgg agtttactaa gaacaatttg attcaaattg ttgggattaa
    47941 ggaagctaat atagaagttg tagaagtgac gacagcgcct gcaggtagtg tagaaggcat
    48001 ggttgttgaa caaagtccta gagcaggtga aaaggtagac ctaaataaga ctagagtcaa
    48061 gatttcaatc tacaaaccta aaacaacttc agctactcct taaaagcaga tggataatca
    48121 aaatgagtaa tcaatctttg tcatgatttc atggcaaaga ttttttttga gtccagattt
    48181 gtgatagaat agagggagtt gataaaagga ggaaagcatg gaagaatcaa aagaattaaa
    48241 tgccgtcatt gatgtgatta tgctagcggg gactattctc cttaaaagtg gctcagaaat
    48301 ccatcgtgta gaagatacca tgattcgaat cgcgcattcg caggggattg tggattgcaa
    48361 tgtccttgcc atgcctgccg ctatcttttt ctctattgaa aataccaata tttcgcgcat
    48421 gaagcgcgtg acctcctctt cttataacat cgaaaaagtc tgcgatgtga accagatttc
    48481 tcgtcagcta gttggggggc agattgactt agaaacagcc tttaagcaat tgacggcctt
    48541 gcaagctcaa ccccttccct atactaagtt gcaggtaact ctggctgcga cctttagtgc
    48601 tcctttcttt tcagttatgt ttagcggaaa tatctacgac gcacttgggg caggagtggc
    48661 gaccttattt ggttttgcct tttccctcta tgtggaaaaa tttatccgaa ttccctttgt
    48721 gacagccttt gctggagcct ttgtctttgg gataattgcc cagttttggg ctcgctacac
    48781 aggttttcct tcaacggcag atttgattat agctggtgcg gtcatgccgt ttgtaccagg
    48841 tattgccttg accaatgcgg tccgtgatat tatgaccaac cacataaact ctggtatgag
    48901 taagatgttt gaatccctgc tcattaccct cgctttaggg gcaggaactt ctgtcgcctt
    48961 ggtattgatg aactaatatg acactaacaa cctttttatt acaagcagta gcaagttttc
    49021 ttgccattat cactttttta atcgtactca atgtgcaacg gtctatgctc ttacctggag
    49081 ggattttggg catgactgtc tggctaatct atctcttgct caaggaaccg accaatgtca
    49141 ttgtagctac cttcattgca gccattattg gttcttgtgt cagccagatt ttaagtattc
    49201 tttataagac acctgctgtg gtctttatct tggccatttt ggcaccgctg gttccaggtt
    49261 atctctccta ccgaacaact gccttttttg tgacagggga ctataataaa gcactggcaa
    49321 gtgcgacctt ggttgtcatg ttggctctgg taatctctat tggaatggct agcggaacag
    49381 tgattctcag actgtatcat tatataaaaa cacatcgagt atcgtagact ttacagaaat
    49441 aaaagaattt tctgaaaaat gagataaata aattaacaac gctttctata tgtgcgagaa
    49501 taccgcactt atgaagaaat tacggctgat tttggtatcc acgaaagcaa cttaatccgt
    49561 cggagccaat gggttgaagt aactcttgtt caaagtggtg ttacgatttc aaaaactcat
    49621 cttagtgctg agaatacggt gattgtggat gcaacagagg taaaaataaa tcgtcctaaa
    49681 aaaatcaact agccaattat tctggtaaaa tagaaatgtc attctatgga acctcaagcg
    49741 attgtcacaa gtcaagggag aattgtttct ttggatatcg ctgtgaacta ttgtcatgat
    49801 atgaagttgt tcaaaatgag tcgcagaaat atcggacaag ctggtaaaat cttggttgac
    49861 agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg taaatccagc
    49921 aaactcaagc cgctaacagc tgaagataaa gcctgtaacc atgcgctatc taaggagaga
    49981 agcaaggttg agaacatctt tgccaaagta aaaacgttta aaatgatttc aacaacctat
    50041 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgttggtat tatcaatcat
    50101 gaactaggat tctagttttg caggaagtct actattttcc ttattgtctg taagtctact
    50161 gaccttgttg tttatcccag tcatggtttc tagttcgggc tcagagtttc aaagtggatg
    50221 gcaagagcat caattgattg ctgagaaggt tagtaaaaca cttgacaaga catttgataa
    50281 ggatgtcaga gaaattccga ccagtcagtt ttatcaaaaa tttgtagatg agatgggaag
    50341 gacttactca ggaaatttga tcctccagga gctgataact gtgaatggag cttataaagc
    50401 tacttatatc gatgaactct ctagcaacta atcattcttt aaaatgatga ccaataagag
    50461 gcttgatttg gtgaatcaag tcttttttct ctcttttact gccatttgtg ataaaatagt
    50521 atagaacgat tttttacatg aatgataaaa cagaggtaaa tatgacaatc ggtattgata
    50581 agattggttt tgcgaccagt caatatgtct tgaaattaca agacttagca gaagcgaggg
    50641 gaattgaccc tgaaaaatta agtaaaggac tcttactcaa ggaattgagt attgcgcccc
    50701 taactgagga catcgtgacc ttggcggcca gtgctagtga ctctatttta actgagcaag
    50761 aaagacaaga agttgacatg gtcattgtag ctaccgagtc aggaattgac cagagtaagg
    50821 ctgcggccgt ctttgtgcat ggcttgctgg gcatccagcc ctttgctcgt agtttcgaga
    50881 ttaaagaagc ctgctatggg gcgacagctg ccctccatta tgccaaattg catgtggaaa
    50941 attctccgga gtccaaggtc ttggtcattg ccagtgatat tgccaaatat ggtattgaaa
    51001 ctccgggaga acccactcag ggtgccggaa gtgtggctat gttgattaca caaaatccac
    51061 gcatgatggc ctttaataat gacaatgtag ctcagacccg tgacatcatg gatttctggc
    51121 gaccaaatta ctcgacaact ccttatgtaa atggtgtcta ttctacccaa caatacttgg
    51181 atagtttgaa aacgacttgg cttgaatatc aaaaacgcta ccagcttact ttggatgatt
    51241 ttgcggctgt ttgtttccac ttgccttatc ctaaattagc gctaaaaggc ttgaaaaaaa
    51301 tcatggataa gagcctgcct caagagaaaa aagacctctt acaaaagcat tttgaccagt
    51361 ctattctcta cagtcaaaag gtggggaata tctacacagg ttcacttttc cttggacttt
    51421 tgtctctctt ggaaaataca gatagcttga aagctgggga taaaatcgtc ctttatagtt
    51481 acggaagtgg agctgtggct gagttcttca gtggtgaatt ggttgaagga tatgaagctt
    51541 atttggataa agaccgcttg aacaagctca accaacgaac tgccctatcc gttgcagact
    51601 atgaaaaggt cttttttgag gaagtaaact tggatgaaac aaactctgcc cagtttgctg
    51661 gctatgaaaa tcaagatttt gccttggttg aaattctcga ccaccaacgc cgttatagca
    51721 aggttgaaaa ataatgaaga taagttggaa tggattttct aaaaaatcat accaagagcg
    51781 cctcgagctg ctaaaagctc aggcgctcct tagtcctgag agacaagcta gtctggagaa
    51841 ggatgaacag atgagtgtga ctgtggcaga ccagctgagt gagaatgtgg tgggaacttt
    51901 ttctctgcct tattcgctgg ttccggaggt acttgtcaac ggtcaggaat acaccgttcc
    51961 ctatgtgaca gaagaaccct ctgtggttgc ggcggccagc tatgccagca aaatcatcaa
    52021 gcgtgcaggt ggttttactg cacaagtcca tcagcgccag atgattgggc aggtagccct
    52081 ttatcaagtt gctaatccta aactagcgca agagaagatt gccagcaaga aagcggagct
    52141 cttggagctt gccaatcaag cctatccttc tatcgttaaa cgtgggggtg gggcgcgtga
    52201 tctgcatgtc gagcagataa aaggcgaacc agactttctc gttgtttata ttcatgtcga
    52261 tacccaggaa gccatgggtg ccaatatgct caacaccatg ctggaagcct tgaaaccagt
    52321 cttagaagaa ctcagtcagg gacagagtct catgggaatc ctgtccaact acgcgaccga
    52381 ttctctggtg actgcaagct gtcgcatcgc ctttcgctac ttgagccgcc aaaaggatca
    52441 aggacgagag attgcggaga aaattgcgtt ggctagtcag tttgcgcagg ctgatcctta
    52501 ccgagctgct actcataata aaggaatttt taatggtatt gatgcgattt tgattgccac
    52561 tggtaatgac tggcgtgcca tcgaagctgg ggcccatgcc tttgccagtc gagatggacg
    52621 ttatcaaggt cttagttgct ggacgctgga ccttgaaaga gaagaattgg tcggtgagat
    52681 gaccctgccc atgcctgtag cgactaaggg tggctctatc ggcctcaacc cacgtgtagc
    52741 tctcagtcat gatctactag gaaatccttc tgccagagaa ttagcccaga ttatcgtgtc
    52801 catcggtctt gcccaaaatt ttgcagccct caaagctttg gtaagtacgg gcatccagca
    52861 aggccacatg aaactacagg ccaaatccct agctctccta gctggggcta gtgaatctga
    52921 agttgctccc ctagtagagc gcctcatctc agataaaacc tttaacctag agacagccca
    52981 gcgctatctc gaaaatttaa gatcataaaa aactcagacg aatcggtctg agttttcttg
    53041 tgtttaaata ctttttcctg gtaatagcgt aactggtaag aagtaaccag ttgtggcgac
    53101 ttccttgcct tcaatctttt gcaagagaag atcaatagtg agacaagcaa tctcttccaa
    53161 aggttgcttg atagtagcca attgagggta gtaattttcg ataaagtagg tcccatcata
    53221 gccgatgacc ttgagctctt ttgggacaga aatgcccaat tcttgagcga ttttaatgac
    53281 cagaatagct gtcaaatcat ccgaagcaaa aatggcatct ggtttttccc gggtcaagat
    53341 attcttgatt tccatttctt ttctgacggg agaaaagtca ctggaaacat tgataatagg
    53401 agcttttggg agtacggatg caaaaccagc gtggcgcagt ccggttggcg aattggaatt
    53461 gtcattccct gtaatcatga tgatagactg ggcacctgtc ttgaccaagg tttgggcagc
    53521 aagaacccca ccagcatagt tgtcagagga gacgacaggg atgtctggcg ataggtttcg
    53581 gtcaaaggaa ataatcggcg ctgtcacacg attgtagtct tcgattccta ggttgtgact
    53641 accagaaatg atgccgtcca cctgattggc ttccaacatt tcgatgtatt cgcgttcctt
    53701 ctcagaatca tgttcactgt tgcagatgat ggtcttgtaa ccatttttga agagttggtg
    53761 ttccaattta tcaatcaatt ctgcatagaa aacattggaa atattgggga aaatcaagcc
    53821 gattaactta gctgattttc cttgcagact acgagccagg ttgttgggtt tatagcccaa
    53881 ttctctcatg gcttcattga ctttttggat ggttttctca gatagatacc cttttttatt
    53941 gataacccga gaaacggtag taggactgac gcctgcaagt ttggcgacat cagttagttt
    54001 tgcgaccata atctaattca tagtaagttc cagttgggtt tccagatttg atcaggatac
    54061 cattttggtc cgcatgtggg aagacacgac cagaaaatac tttttctcct ttattgatga
    54121 aaatttcaaa gacagagtta tcgatgaaga ttgtagcagt agtagcctga ttctcgatag
    54181 ggcaagaacg agttgtccca aattcttggg catactgttc tccagcctgg ctacgatcca
    54241 ctgtcacttg accgtttaca aggtcaaagt tgattgaaag tcccttacct tctttatcag
    54301 caagtaagac aatctcgctc tggctattag cttccaagtt gagttcaagt tcgtaagtgt
    54361 tcttggtttg ggaacggttt gagaaggctt cttcagaagc acgaaggtcc ttaatagcag
    54421 cgactggata ctggtagagc ttgtcgtctt tgatagtgag ttccttgacc aaagagaagg
    54481 ttccttggtg gtcaaaacgg tcagatgggt aagaaacatc tggcaaacca agccagctaa
    54541 ctgctagagc acgcccatca ggagcgttga aggcttgagt tgcataggct tcgaaaccgt
    54601 aatccatgtt ttgaagttga gacacatcta ccattttggc atttttaggg tcaaaggaag
    54661 ccccaatctt atacatattt ggaaagatat tatcgtagtc tagaactttc ttatccaatc
    54721 cttgtggaca gtagagaagg acaggctgtt cctctacaaa gaccagatta ggacattcca
    54781 tcatgtaggc agtacggtcg ttagcaaagt caaggtcgcc aactgcttgc cagtttgtgt
    54841 agtcgttatt gacagccttg tagagacgga cgaagccttt tttctccaag tcttgtccgc
    54901 cgacaatggc ataatattga ccctgaaagt taaaaatttg tggatcgcgg aagtggtcag
    54961 tagagtctgc tggctggtca atcaagatct tgtcaatctt tgtaatctta ccctccttgt
    55021 ccatcaaagc accgatctgg tatgggtgac ggatccagtt tttatcgcga acatttcctg
    55081 tataaaatag gaataagtta tcgccaaatt gcatggcaga accagagtag gcaccgtggc
    55141 tatctaatgg agtatctggt aaaactttga ctccagtttc tctaaagtga atcaaatcat
    55201 cactttctag ctgtgcccaa gattttaaac cgtgggctgc accaaaagga aaattctggt
    55261 aaaagaggat ccacttgcca tcaaagtaag aaaagccatt tgggtcgttg agaagtcctg
    55321 tttttggctc aacatggtaa tgagtatgcc atggagattg tgccatattt tcctttatat
    55381 gttgaatttc ttcttgcgtc caatcttgat aaagtctgta acgacgctca gttgtccatt
    55441 ccattcattc ctccaaaaat cttatcactt ttaatagtaa ctgttttcga taaaaaatgc
    55501 aagcctttta tattaaaaaa gagaaaaaac tgtcaaacga ttatcataaa ataaatacag
    55561 gaaatcaatc aaatttttac gaaaatgtga aagataatga aataaaagac tttttaacca
    55621 aggtttcaaa tttatttttc aaggaattcc tgatgaaaca gtcaaaaaca atcaatctaa
    55681 agcttgccca ctaagtggat agaatatttt tctgcaaaac gcttgacata tttttaaaac
    55741 atgataaaat aatagtcgta agggcgaata aaatcgcttt caaacaagaa caaaatgtta
    55801 tataaggaga tttttgcaaa tgaacaatca ggaaattgca aaaaaagtca tcgatgcctt
    55861 gggcggacgt gaaaatgtca atagtgttgc ccactgtgcg actcgtctac gtgtcatggt
    55921 caaagatgaa gagaaaatca ataaagaagt gattgagaac ttggaaaaag ttcaaggtgc
    55981 tttctttaac tcagggcaat accaaattat ctttggtaca ggtacagtta acaaaatgta
    56041 cgatgaagtt gttgtacttg gcttaccaac atcatctaag gatgacatga aagcagaagt
    56101 tgctaaacaa gggaactggt tccaacgtgc tatccgtact ttcggtgatg ttttcgttcc
    56161 aatcatccca gttatcgtag cgacaggtct cttcatgggt gtgcgtggtc ttttcaacgc
    56221 tcttgaaatg ccacttccag gtgactttgc aacttacaca caaatcttga cagatacagc
    56281 cttcatcatc ttgccaggtt tggttgtgtg gtcaaccttc cgtgtatttg gtggaaatcc
    56341 tgccgttggt atcgttcttg gtatgatgct tgtctctggc tcacttccaa acgcttgggc
    56401 agttgctcaa ggtggtgaag taacagcgat gaacttcttt ggtttcatcc ctgttgttgg
    56461 tttgcaaggt tccgttcttc cagccttcat catcggggtt gtcggagcta aatttgaaaa
    56521 agctgtccgc aaggttgttc cagatgtcat tgacctcttg gtaacaccat tcgtgacact
    56581 tttggtcatg tctatccttg gactctttgt cattggacca gttttccacg ttgttgaaaa
    56641 ctacatcctt attgctacaa aagcgattct tagcattcca tttggtcttg gtggtttctt
    56701 gattggtggg gttcaccaat tgatcgtcgt gtcaggtgtg caccacatct tcaacttgct
    56761 tgaagtgcaa ttacttgctg ctgaccatgc taacccattc aacgctatca tcacagctgc
    56821 tatgacagct caaggtgctg ctactgttgc ggttggtgtt aaaacaaaaa atccaaaact
    56881 gaaaacactt gctttcccgg ctgctctttc tgccttccta ggtattacag agcctgctat
    56941 cttcggggtg aacttgcgct tccgtaaacc attcttcctt tcattgattg ctggtgcaat
    57001 cggtggtgga ttggcttcta tccttggact tgctggtact ggtaatggta tcaccatcat
    57061 ccctggtaca atgctttatg ttggtaacgg acaacttcca caataccttc ttatggtagc
    57121 tgtatcattt gcccttggtt ttgctcttac ttacatgttt ggttacgaag atgaagtaga
    57181 cgcaactgca gctgcaaaac aagctgaagt ggctgaagaa aaagaagaag ttgcgccagc
    57241 agctcttcaa aatgaaacac ttgtaactcc tatcgtcggt gatgttgtcg ctcttgctga
    57301 tgtcaatgac ccagtcttct caagtggagc tatgggacaa ggtatcgctg tgaaaccaag
    57361 ccaaggcgtg gtctatgcac cagctgatgc tgaagtttca attgcctttc caacagggca
    57421 cgcttttggt ttgaaaacaa gaaatggtgc tgaagttttg attcacgttg gtattgacac
    57481 tgtatctatg aacggtgacg gttttgaagc aaaagttgct caaggtaaca aggtgaaagc
    57541 tggcgatgtt cttggaacat ttgactcaaa caaaatcgct gcagctggac ttgatgatac
    57601 aacaatggtt atcgttacaa atacagctga ctacgcttca gtagctccag tcgcaacagg
    57661 ttcagttgcg aagggggatg ctgtgatcga agtgaaaatc taatcaatcc tctctaatgt
    57721 gaaaacgaac aaatgacatg tttgttcgtt tttattagat agtaagattt acagaggaaa
    57781 atctaaaaaa tagagacatt tagactttcg aagtatgcta taataaagaa aataaaaaca
    57841 agaggtttat catgacaaaa ttatatggaa gcttggaagc gggcggtaca aagtttgtct
    57901 gtgctgtcgg tgatgaaaac tttaacgtcg tagaaaaaac acaatttcca acaacaactc
    57961 caatcgaaac aatcgataaa accattgagt tcttctcaaa attcgataac cttgctggtc
    58021 ttgcagttgg ttcatttggg ccgattgata ttgacaaaaa ctcaaaaact tatggcttta
    58081 tcacgacgac tccaaaacca aactgggcaa atgtggactt gcttggtgcc cttcgtcgcg
    58141 ccctaaacgt gccaatgtac ttcacaacag acgtaaacag ctctgcttac ggtgaagtgg
    58201 ttgcccgtaa caatgctggt ggtcgtatcg aaaacttggt ttactacaca atcggtacag
    58261 gtatcggtgc aggtgtcctc caacgtggtg agtttatcgg tggtgtgggt caccctgaaa
    58321 tgggtcatta ttatgttgct agacacccaa tggatattga aaaagagttt aagggtgttt
    58381 gtcctttcca taagggatgt ctagaaggtt atgcagctgg tccaagtttg gaagctcgta
    58441 caggtgtacg tggggaaact attgaattca acaaccctgt ttgggatgtt caagcctact
    58501 atatcgctca agctgcggtt aatgcgacag tgactttccg cccagacgtg attgtctttg
    58561 gtggaggggt catggctcaa caacatatgc tggaccgtgt ccgtgagaaa tttacatctc
    58621 ttcttaatgg ttacctacca gtaccagatg tgcgtgacta tatcgtgacg ccagcagtcg
    58681 caggaaatgg ttctgccaca cttgggaact ttgttcttgc aaaagaagtt tcaaaataaa
    58741 gcacaaaatc cgcttgggaa accaaacgga ttttgtggtt gaaaacaata tttttgagcc
    58801 tttccttaag tgattacgga cggtagcgac tttcttcgaa attccatacc taaactttga
    58861 gacactaggc tcaaagtttc cgaatacctg aaaccattag atttcaggtg tttctatcac
    58921 ggcgggaagg ctaggtaagt cctcgcctca ctatcgaaaa atatgcatga tttccatacc
    58981 aaagtatatt tagtatcaag ctatagttaa tctacgcttt aaaaatccac ttgggaaacc
    59041 aaacggattt tttacgtgtc aaagcatttg ccagaaaaag tcaataatat aggtcagacc
    59101 gtaggtataa accacgaggg taaagggttt ggtcagaatg atgatagtca tgtagcgctt
    59161 gaaactcatc ttggtcaggg cagccagcat acagagaaag tcagctgggc taatgggcca
    59221 aatcatcata aaaataaaga agcggtcaaa acgattgccc ttatctagcc agccgatgta
    59281 cttgtcgtag gtgcgcttgc tgacgacaga ctggacaaag gcagctccgt ataggcgcac
    59341 cagataaaag ataatggcac agccaatcac gatgccgata tagttgtaga tagtcccgat
    59401 gatgtgcccg tagataaaga ccccagccac cgaggtcaag gcccctggaa tgatagggac
    59461 gacagtctgt aaaatctgta aaaagataaa gagaggtgga ccccagatgc ctgcctgctg
    59521 gataaaggca gagagggttt ccttggattg taaaatccca gcctgataag cccaaataca
    59581 gaaaatcaaa ctcccaaccc caccgacaat cgatgagata ttgataactc gctgcagaag
    59641 gggagaaaca gctttcattt gtttatcctg tgacatgtaa actcctcata gatagtatat
    59701 ttctactata ccatattttg gaggagaaag ggggaatgag tcttttttga taaggaatag
    59761 aaagtaaata gcccttcgag acttagaata ggtctgtcaa ctaaaggtta tatgcattct
    59821 aggtttcgaa taatcgcaat tccataaatt taaaagcatt ctaagtttcg aatagcttat
    59881 ctgagataat tttgaggcat tcgcgctttc gaatagtcat tttccctaaa gtttagatgt
    59941 attctgaagc tagaaagact aaaatctaaa agtagtaaga gtctctctct gatggacgta
    60001 atttatggct agtatgaatc ctttgaattg ttagttaatt ttaatattaa tcagttctga
    60061 aataattact aaatatagtt agatggtgaa ttaattattg ctaaatttca agttcaagtt
    60121 agtcatccag aagtcttctc tgggggactt gtagttcaag cattttttag gatagttgtt
    60181 aatccacttt tcgatgaatg cgacttcctt tgtagtcgtt ttcttagttc cctgaggtaa
    60241 ccatctatga atgaacttgt tgtgattttt attagatcct atagtggtgt gcataataga
    60301 tataatagat tgaaactaga atagtacgca tctacttcta aaacattgtt agaaatcgat
    60361 ttgactgtcc cgatctattt gtcctgtttt tatttcattt tactatataa tccttagaaa
    60421 atatatggga caagcggttg aattccgttc cgtccattag tagataaagg attactcctt
    60481 cttgaaatga cagatgaact tgtttcttat aaaaatgttg tctgaaacta ttcgcttttt
    60541 tccagaagtt ttagaggaag aaaactttat gaggaaaaag gagttactca aataacaatt
    60601 caggattaaa aatagacagt tgaggagcgg aaggtataaa ttgagtttgc tactgtataa
    60661 tggatttatc actaatactc ttcgaaaatc tcttcaaacc acgttagctt cgccttgccg
    60721 tagatatagt tactgacttc gtcagttcta tccacaacct caaaacagtg ttttgagctg
    60781 acttcgtcag ttttatctgc aacctcaaag ctgtactttg agcagcctac ggctagcttc
    60841 ctagttcgct ctttgctttt cattgagtat aaaagtgctc caggccatat tttacacagc
    60901 aatagtcttc taaaaatgga caaaaacatt gtaaaggcta tcaaaaagga gtataatgag
    60961 tgcaagaaat ttcggaggtg aaagatgcta gaagtaagaa gtctagagaa aagttttggc
    61021 tccaagcaag ttttgtttgg tattgacttt caagcgcgac caggtcgtat tttgggacta
    61081 gtcggaaaaa atggtgctgg aaaaacaacg attttccata gtattttgaa attcctagaa
    61141 tatcagggag aaatcggtct ggatggtcag gatattcgtc aggagaccta tgctcggatt
    61201 ggttatctgc ctgaagaacg cagtctcatg cctaaattga cagttcttga acaagttcgc
    61261 tacttggcga ctctaaaagg catggatgcc aaagaagtca aagaaaaact ccctcaatgg
    61321 atgaagaggt tgaaagtgaa aggaaagctg acagataaaa tcaagagtct gtcaaaagga
    61381 aatcagcaga agattcagct cattattact ctgattcatg aaccagacct gattatcttg
    61441 gatgagcctt ttagtggatt ggacccagtt aatacagaat tgctcaaaca agtcattttt
    61501 caggaaaaag agcgcggagc aaccattatc ttttctgacc atgtcatgac caatgttgag
    61561 gaactttgtg acgatattct gatgatccga gatggccgtg tggtcttgca cggaccagtt
    61621 caggatgtcc gcaatcaata cgggaaaacg cgtctctttg tttcaagtga acgaagcaag
    61681 gaagaattgg aaaatcttcc tcatgtcaaa caggtgagct tgaccaaaca aggcagttgg
    61741 aaattgattt tggaggatga gagcgctgga agggaactct tcccaatctt gactcaaggt
    61801 caatatatcg caacatttga ccaacaagcg ccaactatcg atgaaatctt taaactagaa
    61861 tcaggagtgg aagtatgaga aatatgtggg ttgtaatcaa ggaaacctat cttcgacatg
    61921 tcgagtcatg gagtttcttc tttatggtga tttcgccgtt cctcttttta ggaatctctg
    61981 taggaattgg gcatatccaa ggttcttcta tggctaaaaa taataaagtg gcagtagtga
    62041 caacagtgcc atctgtagca gaaggactga agaatgtaaa tggtgttaac ttcgactata
    62101 aagacgaagc aagtgccaaa gaagcaatta aagaagaaaa attaaaaggt tatttgacca
    62161 ttgatcaaga agatagtgtt ctaaaggcag tttatcatgg cgaaacatcg cttgaaaatg
    62221 gaattaaatt tgaggttaca ggtacactca atgaactgca aaatcagctt aatcgttcaa
    62281 ctgcttcctt gtctcaagag caggaaaaac gcttagcgca gacaattcaa ttcacagaaa
    62341 agattgatga agccaaggaa aataaaaagt ttattcaaac aattgcagca ggtgccttag
    62401 gattctttct ttatatgatt ctgattacct atgcgggtgt aacagctcag gaagttgcca
    62461 gtgaaaaagg caccaaaatt atggaagtcg ttttttctag cataagggca agtcactatt
    62521 tctatgcgcg gatgatggct ctgtttctag tgattttaac gcatattggg atctatgttg
    62581 taggtggtct ggctgccgtt ttgctcttta aagatttgcc attcttggct cagtctggta
    62641 ttttggatca cttgggagat gctatctcac tgaatacctt gctctttatt ttgatcagtc
    62701 ttttcatgta cgtagtcttg gcagccttcc taggatctat ggtttctcgt cctgaggact
    62761 cagggaaagc cttgtcgcct ttgatgattt tgattatggg tggttttttt ggagtgacag
    62821 ctctaggtgc agctggtgac aatctcctct tgaagattgg ttcttatatt ccctttattt
    62881 cgaccttctt tatgccgttt cgaacgatta atgactatgc ggggggagca gaagcatgga
    62941 tttcacttgc tattacagtg atttttgcgg tggtagcaac aggatttatc ggacgcatgt
    63001 atgctagtct cgttcttcaa acggatgatt tagggatttg gaaaaccttt aaacgtgcct
    63061 tatcttataa atagaagagc cttgcgaaag cgaggttttt aaaggtgaaa agggtggaat
    63121 cacgaaccta attatgtaca cattatgtaa acaagttgct tgaaaactca attgtatagt
    63181 gaactgaatc tggaatagga taatattact tctaaaacat tcttacaaat tgatttgaat
    63241 tccaaaatcc catcgttccg ttcttatttc attttgcgat atagtgaaag gaaataagtc
    63301 agctcacaaa aaacgcataa tatcaaggat tttttgaact gccccccaaa agttagattt
    63361 tttctgtcta acttttgggg ggcagttcat attcaacact tgatactatg cgttttctaa
    63421 ttttaaagac tttttgcctg gtctcttttg ttctatgagt atgttacata tctaggtaaa
    63481 aattatttaa agcaaattaa ccttatttct caagatgtag taggttccga gataaaagat
    63541 agctatgaat atgagttctt caacaatggc tatacctgct cccatataga aatggtcatt
    63601 gagtcctacc agtgaattga catagaaatt agaactaaga ttgaagaaaa gttcaataaa
    63661 tccaatgacg atttggatac caatgtagac tgcaacagcg agtgctgtac ggtattcatt
    63721 gaaaagctgt ccaatggaaa tagccaggta gatgcagagg attcctgaaa tggtatttag
    63781 taggaaggat atacctgtaa gaaagatctg agggagatgt gtttctacaa atgtaatcac
    63841 ataagaaaga ggaatccatt ctggagctgt taaagccaga ataataacag cacttagagc
    63901 caatacagcg gtgctaatca atgaccagat aaaggcaccg attagtttgg ctgtgatgat
    63961 atggtgttca gaaactggca aggtcaaagt cagatagcct tgtcggtcgt agacactacc
    64021 tttgaagcgt ttaataatca agaaaatggt tgaaatcgca agtgtaagca tcaagccacc
    64081 aaagactgta gctagaaaaa gtagcatagt agcctgactt tcttggtaag gtagattttt
    64141 aaagccttgt gtctgtattc cgatgagggc agaaaggact agcacggctg cgtagagggc
    64201 taaataccac ttgttaacat ttttaaattc gtagtgaact aaattccaaa acataaataa
    64261 tctcctttgc ttaggcctta aattcctgac ggaagagttg gtcaatggat tcacctgact
    64321 cgtagcgaat atcatctaca tttccttgac ggacgacttt tccgtctttt aggaagacaa
    64381 tttcatccaa gattggctcg atatcagaaa tcaagtgggt agaaatcaaa acggtagaag
    64441 ttggtgagta gttgttgata atggtattga ggatataagc acgggctgct ggatccaccc
    64501 caccaatggg ttcatccaaa acatagagac gagcatcacg gctcataacc aaaatcagtt
    64561 gaaccttttc tttgtttcct tttgatagtt tcttgagacg actattttca tcaatgccca
    64621 ggtctgcaag tagatgatgg gcgcgttcaa gattgaaatc tttatagaag gtcttgaagt
    64681 aggttagggc ttctttgacc ttcatttgct cattgagata ggtcgtatca ggcaaataag
    64741 ctacaacggc cttggttgct gggcttgggt ccatgtcgtt gatgaggaca cgtccttgat
    64801 ctggttgtaa gaggccatta attagtttaa tcagggttgt ttttcctgag ccgtttggcc
    64861 caagaaggcc gacaattttt ccagctggaa tgtcaagaga aacattttca agggctggtg
    64921 ttgctccata tgatttggat acattttcaa atgctagtaa tgacataggc ttaaactcct
    64981 ttaatataat cactgactac gcctggtagt tcttcttttt catagccaaa atgggtcatg
    65041 gaggaaacga agtgttccaa ttcttcttct gataattgtt tgcgtgactg ggcgattagc
    65101 tccttatcct tagtcacaaa tcgtccagtt gttcgcttgc tgtagacaaa tccttctcgt
    65161 tcaaggtctg ataaggctct ttggatggta ttgggattga caccagcctc gctagctagc
    65221 tccctcacgg ttggaagttg ttgattgggt tccagtgtat gggaaacaat ctgaagcttg
    65281 attttttcca taatctgtaa atagatgggt tttttgttgt caaatgtcca ggacatcttg
    65341 gtctcctttc tcttaccctt ttgtcttaat taaataatac aacaaaacaa aaaacttgtc
    65401 aagcaaaaag aagaattgtt ttgggaatcg cttaaaaaat ggtataatga aaagaaaacg
    65461 ataaggaggg aaaggatgcg ttgtccaaaa tgtggggcta ccaagtcaag tgttatcgat
    65521 agtcgccaag cagaagaagg gaacaccatt cgtagaagac gtgagtgcga cgaatgccaa
    65581 caccgtttta caacctacga acgagtagaa gaaagaacct tagtggttgt taaaaaagat
    65641 ggcacacggg aacaattctc cagagataaa atctttaatg ggattatccg ctcagcccag
    65701 aaacgtcctg tgtcaagtga tgaaatcaac atggtagtca atcgtatcga acagaaactc
    65761 cgtggtcgaa atgaaaatga aattcaaagt gaggacattg gttcactcgt catggaggag
    65821 ttggctgaat tggacgagat tacctatgta cgttttgcta gtgtctatcg tagttttaag
    65881 gatgtcagtg agttagagag cttgctccaa caaatcaccc agtcctctaa aaagaaaaag
    65941 gaaagataaa tgaagccaat tgaccgtttt tcttatctaa agaataatcg ggtgtcgcaa
    66001 gatacctcat ctctggtaca gtgctacctc ccgattatcg gtcaggaggc actgagcctt
    66061 tatctttata cgattagttt ttgggataat ggtagaaagg aatatctttt ttcaagtatc
    66121 ctcaatcatc ttaactttgg aatggataga ctgataaaat cattgaaaat cttatctgct
    66181 tttaatctct tgactctcta tcaaaagggg gatgtttatc agctagccct ccatgctcct
    66241 ctatctagtc aagacttctt ggggcatcct gtttatcgca gactcttaga gaaaaagatt
    66301 ggggactctg ctgtggagga tttgaaagtt gaaagtgctg atggtgaaga aatacctgtc
    66361 tcactcaatc aagtctttcc agaattggca gaactaggca gtcaagaaga ccttggtctc
    66421 aagaagaaag tggccaatga ttttgacttg gaacattttc gccagctgat ggctcgagat
    66481 ggacttcgtt ttgcggatga gcagtccgat gtcttaaacc tctttgctat tgccgaggag
    66541 aagaaatgga cttggtttga aacctatcaa ttggccaagt caacagctgt ttctcaggtt
    66601 atttcaacca aacgcatgcg tgaaaaaatt gctcaaaaac cagtttcctc tgactttagt
    66661 cttaaggaaa caaccattat caaagaagcc aaaagtaaaa ctgccctgca gttcttggca
    66721 gaaatcaagc aaacacgcaa gggaaccatt acccaaacag aaagagaact cttgcaacag
    66781 atggctggct tgggcttgct ggacgaagtc atcaatatca ttcttttatt gacctttaat
    66841 aaggtcgatt cggcaaatat caatgagaaa tatgccatga aggtagccaa tgactatgcc
    66901 tatcaaaaga ttcattcggc agaaaaggca gtcttgcgca tccgtgagcg agaacagaaa
    66961 gcaaaaacac aaaaacagaa tcagactgcc ccagcaaaaa ccaatattcc taaatggagt
    67021 aatcctgaat ataaaaatac gtcatccgct gaggaattag aagagatgga acgccaaacc
    67081 ctagaattat tagcaaaatt agataacgga ggtgattaga tggaaagtgt cggagatgta
    67141 ctcaaacgtc aaccaagtcg ttttcactat caagatttag ttcagaaaat catgaaggat
    67201 cctgatgttg cggcctttgt ccagcaagaa tccctcaatc aggacgagtt gaaccgtagt
    67261 atttccaagt ttaaccaata catcactgag agagataaat tcctccgagg agatacagat
    67321 tatattgcca aaggctacaa gcctatatta gtcatgaacc atggctatgc ggatgtttct
    67381 tatgaagaaa ctcctgaact aatcgcagct gaaaaagaag cggctatcaa gaaacgtctc
    67441 aacttaatta attttccatc tagcctgaaa aatgtcagtt ttttagatgt ttatcgtgat
    67501 gatgttcagc gcttaactgt tctaaaaaga atgatagaat ttgttaacga ttaccccaat
    67561 aatttgaaag gtctttactt gtatggagac tttggtgtgg gtaaaagttt catggtggct
    67621 gccctagctc atgatttatc agaaaaacgt ggtgtatcat ccactctcct ccactatcct
    67681 agctttgtca ttgatgtcaa aaatgctatc agtgatggca atgttaagac cttggtggat
    67741 gagattaagc tgtctgatgt cctgatttta gatgatattg gcgccgagca atcaaccgtt
    67801 tgggtgcgtg acgaaatcct gcaggtcatt ctccaatatc ggatgcagga aaatttaccg
    67861 acctttttca catccaactt caactttgaa gatttggaga agcattttgc gaaagtgaaa
    67921 catggaaatg acgaaacctg ggaagccaga cgggtcatgg aacgcatccg ttatttggct
    67981 gaggagactc gtttagaagg agtaaaccgt cgatgacaga aaccattaaa ttgatgaagg
    68041 ctcatacttc agtgcgcagg tttaaagagc aagaaattcc ccaagtagac ttaaatgaga
    68101 ttttgacagc agcccagatg gcatcatctt ggaagaattt ccaatcctac tctgtgattg
    68161 tggtacgaag tcaagagaag aaagatgcct tgtatgaatt ggtacctcaa gaagccattc
    68221 gccagtctgc tgttttcctt ctctttgtcg gagatttgaa ccgagcagaa aagggagccc
    68281 gacttcatac cgacaccttc caaccccaag gtgtggaagg tctcttgatt agttcggtcg
    68341 atgcagctct tgctggacaa aacgccttgt tggcagctga aagcttgggc tatggtggtg
    68401 tgattatcgg tttggttcga tacaagtctg aagaagtggc agagctcttt aacctacctg
    68461 actacaccta ttctgtcttt gggatggcac tgggtgtgcc aaatcaacat catgatatga
    68521 aaccgagact gccactagag aatgttgtct ttgaggaaga ataccaagaa cagtcaactg
    68581 aggcaatcca agcttatgac cgtgttcagg ctgactatgc tggggcgcgt gcgaccacaa
    68641 gctggagtca gcgcctagca gaacagtttg gtcaagctga accaagctca actagaaaaa
    68701 atcttgaaca gaagaaatta ttgtagaaag tgagaaatta tggccctacc aactattgcc
    68761 attgtaggac gtcccaatgt tgggaaatca accctattta atcggatcgc tggtgagcga
    68821 atctccattg tagaagatgt cgaaggagtg acacgtgacc gtatttatgc aacgggtgag
    68881 tggctcaatc gttcttttag catgattgat acaggaggaa ttgatgatgt cgatgctcct
    68941 ttcatggaac aaatcaagca ccaggcagaa attgccatgg aagaagcaga tgttatcgtc
    69001 tttgtcgtgt ccggtaagga aggaattacc gatgcagacg aatacgtagc ccgtaagctt
    69061 tataagaccc acaaaccagt tatcctcgca gttaacaagg tagacaaccc tgagatgcga
    69121 aatgatatat atgatttcta tgctctcggt ttgggtgaac cactgcctat ctcatctgtc
    69181 catggtatcg gtacagggga tgtactagat gcgattgtgg aaaaccttcc aaatgaatat
    69241 gaagaagaaa atccagatgt cattaagttt agcctgattg gtcgtccaaa cgttggaaaa
    69301 tcaagcttga tcaatgctat cttgggcgaa gaccgtgtta ttgctagtcc tgttgctgga
    69361 acaactcgtg atgccattga tacccacttt acagatacag atggtcaaga gtttaccatg
    69421 attgatacgg ctggtatgcg taagtctggt aaggtttatg aaaatactga gaaatactct
    69481 gttatgcgtg ccatgcgtgc tattgaccgt tcagatgtgg tcttgatggt catcaatgcg
    69541 gaagaaggca ttcgtgagta cgacaagcgt atcgcaggat ttgcccatga agctggtaaa
    69601 gggatgatta tcgtggtcaa caagtgggat acgcttgaaa aagataacca cactatgaaa
    69661 aactgggaag aagatatccg tgagcagttc caatacctgc cttacgcacc gattatcttt
    69721 gtatccgctt tgaccaagca acgtctccac aaacttcctg agatgattaa gcaaatcagc
    69781 gaaagtcaaa atacacgtat tccatcagct gtcttgaacg atgtcatcat ggatgccatt
    69841 gccatcaacc caacaccgac agacaaagga aaacgtctca agattttcta tgcgacccaa
    69901 gtggcaacca aaccaccaac ctttgtcatc tttgtcaatg aagaagaact catgcacttt
    69961 tcttacctgc gtttcttgga aaatcaaatc cgcaaggcct ttgtttttga gggaacaccg
    70021 attcatctca tcgcaagaaa acgcaaataa aaaagtagaa tctggaatga cagttccgga
    70081 tttttttgat ataataaaat aatagaaaac gctatcaaaa gaaagagggt gatgtcggtg
    70141 atggaacatt tgtttaaatt cttactttta gcaccgtact tttattttga taactggatt
    70201 gagaaggcca acagaaatag taagtttttt ccaatttttt attattttta ctggttttac
    70261 atccccttct attctctttt tagccttgct tggacagttg tttcagttct gtttttcaat
    70321 accgtcttga gaaatgtgac agatatcaag ttatggggca tttggtttct ttttattctg
    70381 ctagctattg gtatgaattg gttaacttat tcctgtttca aagaaatgtt tcgcttgaga
    70441 caggaactag ggaagtctaa gggtggaagg cattgattta tatcggtttc tatttgtagg
    70501 aggtggcctt atggtacctc taaaatcatt tattacacgc tattccaagg tttatattgg
    70561 taataacatt taatagaacg aaactaaaga aaacaattta aaagaggagg tttgtgatgg
    70621 aacacttgtt taaaatgata atcttattac cctgttttta ctttttcagc tggattgaca
    70681 aggataatag agaaagtaaa tttttcccaa ttttttacta tttttactgg atttacatca
    70741 ccctctatgc tctttttagc cttgcttgga cagttttttc agttctgttt ttcaatatcg
    70801 tcttgagaaa tttgacagat atcaagttat ggggtatttg gctattatta ctacttatcg
    70861 cttttgctag tgattggtta gcctatgtct ttttcaaaaa aatgcttgac ttgagacggg
    70921 aactagggaa gtctaaaggc ggaaggcatt gatttatact cttcgaaaat ctcttcaaac
    70981 cacgtcaacg tcgccttgga ttatatatgt aactgacttc gtcagtctta tctacaacct
    71041 caaagcagtg ctttgagcaa cttgcggcta gtttcctagt ttgctctttg attttcattg
    71101 agtattatat tactttctat ttgtaggagg tggcttatga agattcctct cttaactttg
    71161 gcaaggcata aatttgttta tgtcttgctt actttgcttt ttcttgcttt ggtttatcgt
    71221 gatgttttga tgacttattt cttttttgat attcatgcgc ccgatctagc taaattcgat
    71281 ggacaagcaa ttaaaaatga cttattaaaa tcagcattag attttcgtat tctccagttc
    71341 aatctaggtt tttatcaatc atttattatt ccaatcatca ttgttttgct aggttttcaa
    71401 tatattgagc tgaaaaataa agttttacga ttgagtattg gaagagaagt gagttatcaa
    71461 gggttaaaaa gaaagttgac tttgcaagtt gcaagtatcc cttgtttgat atatttagtg
    71521 actgtgctga taattgcaat tataacctat ttctttggga ctttttctcc tcttggatgg
    71581 aattctctat tttctgatgg aagtggttta caaagactcc tagatggaga gataaaaagc
    71641 tatttgttct ttacttgtgt cctactaatc ggtattttca tcaatgcaat ctatttttta
    71701 caaatagttg attatgtggg gaatgtgact cgttcggcaa tcacctattt gatgtttctt
    71761 tggcttggtt ctatgctgct ctatagtgcc ttgccttact atatggttcc tatgacgagt
    71821 ttgatgcaag ctagctatgg ggatgtaagt ttgatgaaac tctttactcc ttatatcctt
    71881 tatattgtcc cttatatggt acttaaaaaa tatgaagata atgtttaaga attttaacaa
    71941 tattttgcta aagagaaaga tcgttttact acttcgtata gttctgatga tgattttgat
    72001 aaactatcta ttgtcaacag cggttcaaaa gcaggatgct gttatctttt tcaagagaga
    72061 attgatttca atcttttcct ataatgacta ttctgaagcg aatttagaaa tccccaaact
    72121 cttgttaaac ctttcgcttt tcatggtagg atggctctct gtcattttac ttgaaagtga
    72181 tttggcagac cattaccatc acttgattcg ctatcaatca agctcctttt tcgattatac
    72241 aaggaaacga ttggttgtca tttctaaatt ttttactcaa gatttgtttg tctggtttct
    72301 tggtttactt ccgctaggaa ttcatttcaa aacagtcgca cttttctttt tacttgctca
    72361 gttaatgatg ttgtacttac tactgtctta tctgatagca ctgattagtg cgggcgctgg
    72421 tttttctttt tttctctatt ttttggcatt tgtgggacaa gaatggatga tggatcatat
    72481 tgtaacagtg tatttactac tcttaagttt attagttatg ttgattgtta gtcgcttgga
    72541 agagaaattt aagaaaggat aaacgatgag acttgaaatt ataaatggac agaaaattta
    72601 tgggaaaaga cctattttaa atcagttgaa tttggtgttt caatcaggaa aaatttatgg
    72661 acttaaaggt gataatggat ctggcaagac ggttctttta aagatacttg ctggttatat
    72721 taagcttgac aaaggaaaag ttcttcaaga tggtaaagtt tacggggtaa aaaatcatta
    72781 tattcaggat gcaggaattt taattgaaaa agtcgagttt ttatctcatt tatccctgag
    72841 agaaaatttg gaactgttaa ggtatttttc atctaaagtt acggaaaaaa gaattgccta
    72901 ttggattcaa tactatgatt tacaggaatt tgaagatgtt gaataccggc atttatcctt
    72961 gggaacaaag caaaaaatgg ccttgattca agcctttatt tcctctcctt ctatactctt
    73021 tctcgatgaa cctatgaatg ctttggatga gaagagtgtg aggttaacca aacaggtcat
    73081 tttatcttac ctgaaaaaag aaaatggtct ggttatcctg acgtcgcaca tatcggaaga
    73141 tatttcagac ctttgtacag atgtattagt tgtcgaaaat ggacatatac aatatgtaaa
    73201 ggatatacaa tcctaggaga tggcttatgg cacatctaaa atcatttatt acacgctatt
    73261 ccaaggttta tattggttta gttctgctga tctggctgtc tttcttcttt atcccttggg
    73321 atagagcgat tctgggggta aggattgaca tcttcatcat acagaaagtc ttgctagttt
    73381 ttggaattct gtccattctc atggccttgc tgtccaagaa agtcagtctc tttgtttttg
    73441 gactgatttg ctgtctttct ctttggatta acttatttat cacatttgcc attttgccga
    73501 tttttggcaa ttaaacagtc ataaaagtcg gagaggttag cttgaaaact aacctctttt
    73561 tccttttcaa aatggggatt cttccttgaa aataatcagt aattgtgcta aaattaaagg
    73621 aacattctaa aatattcgga atttaaagta aggaaaaaca tggctaatat tttaaaaaca
    73681 attatcgaaa atgataaagg agaaatccgt cgtctggaaa agatggctga caaggttttc
    73741 aaatacgaag accaaatggc tgctttgact gacgaccaac taaaagcaaa aacagttgaa
    73801 tttaaggaac gttatcaaaa tggagaatca ctggattcat tgctttacga agcatttgcg
    73861 gttgtccgtg aaggtgccaa acgtgtccta ggtctcttcc cttataaggt tcaggtcatg
    73921 ggggggattg ttcttcacca tggtgacgtg ccagagatgc gtacagggga agggaaaacc
    73981 ttgactgcga ccatgccggt atacctcaat gccctttcag gtaaaggggt tcacgtagtt
    74041 acggttaatg aatacctgtc agaacgtgac gcgactgaga tgggtgaatt gtactcttgg
    74101 cttggtttgt cagtagggat taacttggct accaaatctc caatggagaa aaaagaagcc
    74161 tatgagtgtg atattactta ctcaactaac tcagaaatcg gatttgacta ccttcgtgac
    74221 aacatggtcg ttcgcgccga aaacatggta caacgtccgc ttaactatgc cttggtcgat
    74281 gaggttgact ctatcttgat tgacgaggct cgtacacctt tgattgtatc aggtgccaat
    74341 gcggttgaaa ccagtcagtt gtatcacatg gcagaccact atgtaaaatc tttgaacaaa
    74401 gatgactaca tcatcgatgt gcagtctaag actattggtt tgtctgattc agggattgac
    74461 agggctgaaa gctacttcaa acttgaaaac ctctatgaca tcgaaaacgt ggctttgact
    74521 cactttatcg ataacgccct tcgtgccaac tacatcatgc ttctcgatat tgactatgtg
    74581 gtgagcgaag agcaagaaat cttgattgtc gaccaattta caggtcgtac catggaaggt
    74641 cgtcgttatt ctgatggatt gcaccaagct attgaagcca aagaaggtgt gccaatccag
    74701 gatgaaacca agacatctgc ctcaatcacg taccaaaacc ttttccgtat gtacaagaaa
    74761 ttgtctggta tgacgggtac aggtaagact gaggaagaag aattccgtga aatctacaac
    74821 attcgtgtta ttccaatccc aacaaaccgt cctgttcaac gtattgacca ctcagacctt
    74881 ctttatgcaa gtatagaatc taagtttaaa gcggttgtcg aagacgttaa ggctcgttac
    74941 caaaagggtc aacctgtctt ggttggtaca gtagcggttg aaactagtga ctacatttct
    75001 aagaaattgg ttgcagctgg tgttcctcac gaagtcttga atgccaaaaa ccactataga
    75061 gaagcccaaa tcatcatgaa tgctggtcaa cgtggtgccg ttaccatcgc aaccaacatg
    75121 gcgggtcgtg gtaccgacat caagcttggt gaaggtgttc gtgaacttgg aggactttgt
    75181 gttattggta cagaacgtca tgaaagtcgt cgtatcgata accagcttcg tggacgttca
    75241 ggtcgtcaag gagatccagg tgagtcacaa ttctacctat ctcttgaaga tgatttgatg
    75301 aaacgttttg gttctgaacg cttgaaggga atctttgaac gcttgaacat gtctgaagag
    75361 gcgattgagt ctcgcatgtt gacgcgtcag gttgaagcag cgcaaaaacg tgtcgaagga
    75421 aataactacg atacccgtaa acaagtcctt caatacgacg atgtcatgcg tgaacaacgt
    75481 gagattatct atactcaacg ttacgatgtc atcactgcag atcgtgactt ggcacctgaa
    75541 attcaggcaa tgatcaaacg cacgattggt cgtgtcgttg acggtcatgc gcgtgctaaa
    75601 caagatgaga aactagaggc aattttgaac ttcgctaagt ataacttgct tcctgaagat
    75661 tctattacga tggaagactt gtcaggcttg tctgataagg ccatcaagga agagcttttc
    75721 caacgtgcct tgaaggttta cgatagtcag gtttcaaaac tacgcgatga agaagcagtt
    75781 aaagaattcc aaaaagtttt gattctacga gtggtggata acaagtggac agatcatatc
    75841 gatgcccttg atcaattgcg taacgcggtt ggacttcgtg gctatgctca gaacaaccct
    75901 gttgttgagt atcaggcaga aggtttccgt atgtttaatg atatgattgg ttcgattgag
    75961 tttgatgtga cacgcttgat gatgaaagca caaattcatg aacaagaaag accacaggca
    76021 gaacgtcata tcagtacaac agcgactcgc aatatcgctg ctcaccaagc aagtatgcca
    76081 gaagatttgg atttgagcca gattggacgc aatgaacttt gcccatgtgg ttctggtaag
    76141 aaatttaaaa actgtcacgg taaaagacaa taaaatgaga tagtttagag gcggatatct
    76201 tgtgaaaagt aaatttttac tgggtatccg tttgctttat aaggagatga gttatggtat
    76261 ttacagcaaa aagctctaaa ataaatatag aagaagttcg tgccttgtca aaattagaag
    76321 gtcaggcttt ggagaggaaa tcacagcgag atcaagagct agaagccatt atacgtggag
    76381 aagaccagcg aattctcttg gtaatcgggc catgctcatc tgacaacgaa gaagctgtcc
    76441 ttgaatacgc taagcgtttg gcagtcctac aagaagaagt ggcagatcgt atctttatgg
    76501 ttatgcgtgt ttatactgcc aaaccccgta ccaacggaga tggctataag ggcttgattc
    76561 accagcctaa cgcgacagaa gcgcctagtc ttatcaatgg aatcaaagcc gttcgccatc
    76621 ttcactatcg tgtcatcaca gaaacaggga tgacaactgc tgatgaaatg ctttatcctg
    76681 aaaaccttcc gcttgtagat gatttgattt cttacatggc agttggtgcc cgttcagttg
    76741 aagaccagca acaccgcttt gtggcaagtg gggcaggatt ttctactggt tttaaaaatc
    76801 caacctctgg aaatctcaat gtcatgttta atgggattta tgctgctcaa aacaaacaaa
    76861 gtttcctttt cttaggaaaa gaagtagaaa caactgggaa cccgctttca cacgctattc
    76921 ttcgtggtgc tcttaatgag tatggaaaaa atattcccaa ctactattat gacaatttaa
    76981 ttgataccat tgcccagtat gagaaaatgg gcttggaaaa tccttttatc atcattgata
    77041 ccaatcatga caattctggt aagcagtata ttgaacagat ccgaattgtc cgccagacct
    77101 tgattaaccg tgcttggaat gaaaaaatta agcagttcgt tcgtggtttt atgattgagt
    77161 cttatctgga agatggtcga caaaatgagc cagaagtatt tggtaagtct atcacagacc
    77221 cttgcctggg ttgggataac acagaagctc ttgtcagaga aatttacaaa acgttaggag
    77281 aataagatgg catttattga aaaaggtcaa gaaatcgata tggaagtcat caaggctgaa
    77341 acccaattgt ctgcggaagc cttgagactc aaggaaagcc gtgacaggga attggcagat
    77401 attatttcag gggaagatga ccgtattctc ttggtgattg gtccttgctc ttctgataat
    77461 gaagaggcgg tcttggaata tgctcgccgt ttatctgcct tgcaaaagaa ggtagcggat
    77521 aagattttca tggtcatgcg cgtgtatact gctaagcctc gtaccaatgg agacggctat
    77581 aaaggattgg ttcaccagcc agatacttct aaggctccaa gcctgattaa cggcttgcag
    77641 gctgtgcgcc agttgcacta ccgcgtgatt acagagactg gtttgacaac ggcagatgag
    77701 atgctttatc cgtcaaatct gatcttggtg gatgacttgg tcagctacca tgccgttgga
    77761 gctcgttctg tggaagacca ggagcaccgc tttgtggctt ctgggattga tgcaccagta
    77821 gggatgaaaa atccaacctc aggaaatttg ggtgttatgt ttaacgccat ctatgctgct
    77881 caaaacaagc aaaccttcct ttatcatggg caggaagttg agacatcagg taatcctttg
    77941 gcccatgtta tcctccgtgg agcagtcaac gagtatggca attatatgcc gaattactac
    78001 tatgaaaacc tactccaagc cattgaacgc tatgaaacca tgggacttga aaatcctttt
    78061 atcctcattg acaccaacca tgataactca ggcaagcaat atatggagca gattcgaatt
    78121 gttcgccaga ccttgcagaa tcgtgattgg aatgagaaaa ttaaaaagac ggttcgagga
    78181 tttatgattg aatcttacct agcagatggt cgtcaaaacc aaccagagat ctttggttgc
    78241 tctattactg acccttgcct aggttgggaa aatacagagg ccttggtaga agagatttat
    78301 gttaccttga caaaataagt gaaaaggatg gagttgggga atctcaactc cttttgatga
    78361 gaatgatagt tggacacgga attgacatcg aagaattggc ttcgatagaa agcgcagtta
    78421 cacgacatga aggatttgct aagcgtgtac tgaccgctca ggaaatggag cgcttcacca
    78481 gtctcaaagg acgcaggcaa atagaatatt tagctggtcg ctggtcggct aaggaggcct
    78541 tttccaaggc tatgggaacg ggcattagca agctcggttt tcaggatttg gaagtcttga
    78601 acaatgaacg tggggcgcct tattttagtc aggcaccatt ttcaggaaag atttggctgt
    78661 ctatcagcca caccgatcag tttgtgatag ccagtgtcat tttggaggaa aatcatgaaa
    78721 gctagtccac atagaccaac caaggctctg attcatctgg gagctattcg acaaaatatt
    78781 cagcaaatgg gggctcatat ccctcaagga acgctcaagt tggctgtggt caaggccaat
    78841 gcttatggtc atggagctgt tgccgttgcc aaggcaattc aagatgatgt taatggcttt
    78901 tgcgtttcca atatcgatga agccattgaa ctcagacaag ctggactcag caagccaatc
    78961 ctcattttag gagtttctga aatcgaagct gttgctctag ctaaagaata tgacttcacc
    79021 ttgacagtgg ctggactgga gtggattcaa gcactcttag ataaggaagt ggacctaact
    79081 ggattgacag tccacctcaa gattgattca gggatgggac ggattggttt tagagaggcc
    79141 agtgaggttg agcaggctca agatttgctc caacaacacg gtgttcgtgt tgaaggaatc
    79201 tttacccact ttgctactgc tgatgaggaa tcagatgact attttaatgc ccagttagaa
    79261 cggtttaaaa ctattttagc tagtatgaag gaagttccag agctggttca tgctagcaat
    79321 tctgcaacga ctctttggca tgtagagact attttcaatg cggttcgtat gggagatgcc
    79381 atgtatggcc tcaatccaag tggagcggtc ttggatttgc cttatgattt gataccggcc
    79441 ttgaccttgg agtctgctct ggttcatatc aagacagttc cagctggtgc ttgcatgggc
    79501 tatggagcaa cttatcaagc ggatagcgag caagtcatcg cgaccgtgcc aatcgggtat
    79561 gcagatggat ggacaagaga catgcaaaat ttctctgtct tggtagatgg ccaagcttgc
    79621 ccaattgtcg gcagggtttc gatggaccaa atcactattc gattgcctaa gccttaccca
    79681 ctcggaacca aggtaacctt gattggctcc aatggggata aggaaatcac tgcaactcag
    79741 gtagcgacct accgcgtaac cattaactat gaggtggttt gcctcctcag cgaccgtatt
    79801 ccgagagaat attattagaa aagaaaggag tggagcatga atctacatca acccttgcat
    79861 gtcttgcctg gtgtgggacc aaagtcagca gaaaaatacg ccaaactagg aattgaaaac
    79921 ttgcaagatc tcttgctcta ctttcctttc cgttatgaag acttcaaaac caagcaggtg
    79981 ctggagctgg aagacggtga gaaggcagtt ctttctggtc aggtagtgac tcctgctagt
    80041 gtccagtatt atggtttcaa gcgcaatcgc ctgcgtttta gtctcaagca gggagaggtc
    80101 gtttttgcgg tgaatttctt taaccagccc tatctggctg ataaaataga gttgggagca
    80161 acccttgctg tctttggaaa atgggaccgc gctaaggcta gtctgactgg gatgaaggtt
    80221 ctggctcagg tagaagatga cctccagcct gtctatcgtc tggctcaggg aatcagtcag
    80281 gccagtctgg tcaaggtcat caagacggct tttgatcagg gactggacct cttgatagaa
    80341 gaaaatctgc cccagtcttt actagacaaa tacaaactca tgtcccgttg tcaggcagtc
    80401 cgagctatgc attttccaaa ggatttggca gaatacaagc aggctcttcg ccgtatcaag
    80461 tttgaggaac tcttttattt ccaaatgcag ctgcagacgc tcaagtctga aaatagagtt
    80521 cagggaagtg gtctggttct ggattggtct caggaaaaag tgacagcagt taaagcaagt
    80581 cttccttttg ccctgaccca agctcaggaa aagagtttgc aggaaatttt aactgatatg
    80641 aagtccgacc accacatgaa tcgtctccta caaggagatg tggggagtgg aaaaacggta
    80701 gtcgctggct tggccatgtt tgcggcagtg acagcaggtt atcaggctgc cctaatggta
    80761 ccaacagaaa tcctcgcaga gcaacacttt gagagtttac agaacctttt tcccaatttg
    80821 aaactggctc tcttgacagg ttccttgaaa gctgcagaaa agagagaagt cttggagacc
    80881 attgccaagg gtgaggctga tttgattata ggaactcacg ctctgataca agatggggtg
    80941 gagtatgctc gtcttggttt gattattatc gatgagcagc accgttttgg tgtagggcaa
    81001 aggcgtattt tacgggaaaa aggtgacaat ccagatgtcc tcatgatgac ggcgactccc
    81061 attccacgga cgcttgccat cacagccttt ggagatatgg atgtttccat tatcgaccag
    81121 atgccagcag gtcggaagcc tattgtgacg cgctggatca aacatgagca actacctcag
    81181 gtcttgactt ggttagaggg ggaaattcaa aaaggttccc aagcctatgt catctctcct
    81241 ttgattgaag aatcagaagc tctagatttg aaaaatgcca ttgccttatc agaggagttg
    81301 acgactcatt ttgcaggcaa ggcagaggtg gctcttctac atggtaggat gaagagtgac
    81361 gaaaaagacc agatcatgca ggatttcaag gagagaaaga cggatattct ggtttcgacg
    81421 acggttattg aggttggggt caacgttccc aatgcgactg tcatgattat catggatgcc
    81481 gatcgcttcg gtctcagtca acttcaccag cttagaggtc gtgtcggtcg gggggacaag
    81541 cagtcctacg ctgttctcgt tgccaatccc aagacggatt ctgggaaaga ccgcatgcgc
    81601 atcatgacag aaacgaccaa tggatttgtc cttgcggagg aagatttgaa aatgcgtggt
    81661 tctggtgaga tttttggaac cagacagtca ggacttccag agttccaagt ggctgatatt
    81721 atcgaagatt ttccgatttt agaagaagca agaaaggttg ctagctacat tagttctata
    81781 gaagcttggc aagaagatcc agagtggcgc atgattgccc ttcatctgga aaagaaagaa
    81841 catctggatt aagctttctc taaggaaaac ttaagctagt ttttaggttt ggctcttata
    81901 ctaaagtcat caaaaagaaa cgaggactct catatgacag taacgattaa agtaaattac
    81961 caaaccactt tccaaaagaa ggaagcaaaa aactagtata aacagaagag agagcgaaat
    82021 gctctttttc gtttctaaaa ctactttcag cccatcatcc taaaagtaaa gaatctaaat
    82081 tcactttcta tttatccttc tttcttgcat tgattacata gatatgctac agttgtggta
    82141 acgattacaa aataaaagga gcatgctatg aaaaatccag ctttgctaga agaaattaag
    82201 acctatagag gaagggatga ggttccggaa gactttgatg ctttctggga tggggaagtg
    82261 aaaaatgttt ccacgcttcc atcctaccac ttggaggaaa gagatttcca cattcctcaa
    82321 gtcaagtgct atgagttaac atttgaagga agcaaggaag gaaaggtcta tgcacgcatt
    82381 gttcttccaa agagtgagga gaaggttcca ctaatcttcc attttcatgg ttatatggga
    82441 cgtggctggg actgggccga catgctgggc ttcaccgtag ctggttacgg tgttgtttcc
    82501 atggatgtgc ggggccagtc aggttactca caagacggct tgcgttctcc tttaggaaat
    82561 accgtgaagg ggcatattat ccgtggtgct atggaaggtc gggaccacct cttttataag
    82621 gatgtttatc tggatattta ccagttggtc gaaattgttg ctagtctgtc tcaggttgat
    82681 gagaagcgtc tttctagcta tggtgcctca caaggagggg ctctagctct agttgcagca
    82741 gcgctcaatc ctcgaattca gaaaacagtt gccatttatc ccttcttgtc agacttcaga
    82801 cgggtgattg agattggtaa tactagcgag gcttacgacg aacttttccg ttatttcaag
    82861 tttcacgacc ccttccatga aacagaggag gaaatcatgg cgacccttgc ctatatcgat
    82921 gtcaaaaatc ttgcccatcg tatccaaggt gaggttaaga tgattacggg cttggacgac
    82981 gatgtttgct atcccattac ccagtttgcg atttataatc gtctgacctg cgataaaacc
    83041 tatcgtatca tgcctgagta tgctcacgaa accatgaatg tatttgtcaa tgaccaagtc
    83101 tacaactggc tctgtggaag tgagattcct tttaaatatc taaaataagg agtcgactct
    83161 aagcacaaaa tcttaaaaat tacaaacacg catagtatca ggggattaag aaaacttgat
    83221 actatgcgtt ttatcatgga aatatagtaa aatgaaacaa gaacaggaca a
//
LOCUS       DAVKXA010000003        65075 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKXA010000003 DAVKXA010000000
VERSION     DAVKXA010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.003"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(491..2218)
                     /gene="ezrA"
                     /locus_tag="VW883_000220"
     CDS             complement(491..2218)
                     /gene="ezrA"
                     /locus_tag="VW883_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0273420.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2300..4246)
                     /gene="gyrB"
                     /locus_tag="VW883_000221"
     CDS             complement(2300..4246)
                     /gene="gyrB"
                     /locus_tag="VW883_000221"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0273421.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4261..4824)
                     /locus_tag="VW883_000222"
     CDS             complement(4261..4824)
                     /locus_tag="VW883_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0273422.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4909..5463)
                     /locus_tag="VW883_000223"
     CDS             complement(4909..5463)
                     /locus_tag="VW883_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0273423.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5474..6697)
                     /locus_tag="VW883_000224"
     CDS             complement(5474..6697)
                     /locus_tag="VW883_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0273424.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6734..9184)
                     /locus_tag="VW883_000225"
     CDS             complement(6734..9184)
                     /locus_tag="VW883_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0273425.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9384..10313)
                     /locus_tag="VW883_000226"
     CDS             complement(9384..10313)
                     /locus_tag="VW883_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0273426.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10453..10740
                     /locus_tag="VW883_000227"
     CDS             10453..10740
                     /locus_tag="VW883_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0273427.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10774..12108)
                     /gene="ciaH"
                     /locus_tag="VW883_000228"
     CDS             complement(10774..12108)
                     /gene="ciaH"
                     /locus_tag="VW883_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0273428.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12098..12772)
                     /gene="ciaR"
                     /locus_tag="VW883_000229"
     CDS             complement(12098..12772)
                     /gene="ciaR"
                     /locus_tag="VW883_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0273429.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12882..15428)
                     /locus_tag="VW883_000230"
     CDS             complement(12882..15428)
                     /locus_tag="VW883_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0273430.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15551..15991)
                     /locus_tag="VW883_000231"
     CDS             complement(15551..15991)
                     /locus_tag="VW883_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0273431.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCVVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(15966..16835)
                     /locus_tag="VW883_000232"
     CDS             complement(15966..16835)
                     /locus_tag="VW883_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0273432.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAESHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16877..17605)
                     /locus_tag="VW883_000233"
     CDS             complement(16877..17605)
                     /locus_tag="VW883_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273433.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17613..18092)
                     /locus_tag="VW883_000234"
     CDS             complement(17613..18092)
                     /locus_tag="VW883_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0273434.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18103..18801)
                     /locus_tag="VW883_000235"
     CDS             complement(18103..18801)
                     /locus_tag="VW883_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0273435.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18794..19060)
                     /locus_tag="VW883_000236"
     CDS             complement(18794..19060)
                     /locus_tag="VW883_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0273436.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19128..20054)
                     /locus_tag="VW883_000237"
     CDS             complement(19128..20054)
                     /locus_tag="VW883_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0273437.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRSDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20129..20944)
                     /locus_tag="VW883_000238"
     CDS             complement(20129..20944)
                     /locus_tag="VW883_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273438.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20948..21268)
                     /locus_tag="VW883_000239"
     CDS             complement(20948..21268)
                     /locus_tag="VW883_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0273439.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21475..21555)
                     /locus_tag="VW883_000240"
                     /pseudo
     CDS             complement(21475..21555)
                     /locus_tag="VW883_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21599..23596)
                     /gene="metG"
                     /locus_tag="VW883_000241"
     CDS             complement(21599..23596)
                     /gene="metG"
                     /locus_tag="VW883_000241"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0273440.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQVYVDRMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWILAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23720..24979)
                     /locus_tag="VW883_000242"
     CDS             complement(23720..24979)
                     /locus_tag="VW883_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0273441.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24981..25682)
                     /locus_tag="VW883_000243"
     CDS             complement(24981..25682)
                     /locus_tag="VW883_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273442.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAVYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25666..26865)
                     /locus_tag="VW883_000244"
     CDS             complement(25666..26865)
                     /locus_tag="VW883_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0273443.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQVPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27151..28497
                     /gene="gor"
                     /locus_tag="VW883_000245"
     CDS             27151..28497
                     /gene="gor"
                     /locus_tag="VW883_000245"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0273444.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28694..29230
                     /locus_tag="VW883_000246"
     CDS             28694..29230
                     /locus_tag="VW883_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0273445.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            29285..29365
                     /locus_tag="VW883_000247"
                     /pseudo
     CDS             29285..29365
                     /locus_tag="VW883_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29434..29649)
                     /locus_tag="VW883_000248"
     CDS             complement(29434..29649)
                     /locus_tag="VW883_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0273446.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29747..30067
                     /locus_tag="VW883_000249"
     CDS             29747..30067
                     /locus_tag="VW883_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273447.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30097..30435)
                     /locus_tag="VW883_000250"
     CDS             complement(30097..30435)
                     /locus_tag="VW883_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273448.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30447..31166)
                     /gene="trmD"
                     /locus_tag="VW883_000251"
     CDS             complement(30447..31166)
                     /gene="trmD"
                     /locus_tag="VW883_000251"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0273449.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31156..31674)
                     /gene="rimM"
                     /locus_tag="VW883_000252"
     CDS             complement(31156..31674)
                     /gene="rimM"
                     /locus_tag="VW883_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0273450.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31705..32493)
                     /locus_tag="VW883_000253"
     CDS             complement(31705..32493)
                     /locus_tag="VW883_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0273451.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDEYGPELYLKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32597..32840)
                     /locus_tag="VW883_000254"
                     /pseudo
     CDS             complement(32597..32840)
                     /locus_tag="VW883_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(33070..33309)
                     /locus_tag="VW883_000255"
     CDS             complement(33070..33309)
                     /locus_tag="VW883_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0273452.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33329..33601)
                     /gene="rpsP"
                     /locus_tag="VW883_000256"
     CDS             complement(33329..33601)
                     /gene="rpsP"
                     /locus_tag="VW883_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0273453.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33796..33996
                     /locus_tag="VW883_000257"
     CDS             33796..33996
                     /locus_tag="VW883_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273454.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMNLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            34475..34687
                     /locus_tag="VW883_000258"
     CDS             34475..34687
                     /locus_tag="VW883_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273455.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            34771..35574
                     /locus_tag="VW883_000259"
     CDS             34771..35574
                     /locus_tag="VW883_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0273456.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKKGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(35630..37171)
                     /locus_tag="VW883_000260"
     CDS             complement(35630..37171)
                     /locus_tag="VW883_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0273457.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKILLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(37173..37655)
                     /locus_tag="VW883_000261"
     CDS             complement(37173..37655)
                     /locus_tag="VW883_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0273458.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(37655..38740)
                     /gene="rlmN"
                     /locus_tag="VW883_000262"
     CDS             complement(37655..38740)
                     /gene="rlmN"
                     /locus_tag="VW883_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0273459.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQINLAVS
                     LHALNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLRFNTMKRDRQKAVAAVNP"
     gene            complement(38761..39291)
                     /locus_tag="VW883_000263"
     CDS             complement(38761..39291)
                     /locus_tag="VW883_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0273460.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFALVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(39448..40053)
                     /locus_tag="VW883_000264"
     CDS             complement(39448..40053)
                     /locus_tag="VW883_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0273461.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(40226..41263)
                     /locus_tag="VW883_000265"
     CDS             complement(40226..41263)
                     /locus_tag="VW883_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0273462.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(41297..42232)
                     /locus_tag="VW883_000266"
     CDS             complement(41297..42232)
                     /locus_tag="VW883_000266"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0273463.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDLRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDCITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42785..43975)
                     /locus_tag="VW883_000267"
     CDS             complement(42785..43975)
                     /locus_tag="VW883_000267"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0273464.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGCFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(44190..45533)
                     /locus_tag="VW883_000268"
     CDS             complement(44190..45533)
                     /locus_tag="VW883_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0273465.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45913..47565)
                     /locus_tag="VW883_000269"
     CDS             complement(45913..47565)
                     /locus_tag="VW883_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465985.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0273466.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGLLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVTSGVDLPKFIQKKA
                     PKDGSTYFNRTRVFAEEPTTKTYIDSVNDGTWTFKGYDAASAVVNKANVEFVGKWEFK
                     ANPTNAETYTPQVTEETIKVGQTPDLTDNVTNLPNLPAGTKVVDITPAGQIDTTKPGT
                     YTGKVRVDYPDGSSTEVSVSVNVLPAPETQTYKVTYRFESATADNNLPAEVLSLLPQS
                     GTYTTSSSVAIAFVPEAPMPVEVAVANGTWTFLGYQEVEEGSNLTFVGKWVFEAKQDP
                     SPQPQPAPTPQPAPQPNPVPPVNPGGEQGTDNNQADRHQSEQPRKPEENPPAQGPAGE
                     KEKQATLPNAGSTAPLSLTGLVTSSLLAGLAVLLLGRKRKDD"
     gene            complement(47771..48586)
                     /locus_tag="VW883_000270"
     CDS             complement(47771..48586)
                     /locus_tag="VW883_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0273467.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            complement(48638..50818)
                     /locus_tag="VW883_000271"
     CDS             complement(48638..50818)
                     /locus_tag="VW883_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0273468.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(51104..52030)
                     /locus_tag="VW883_000272"
     CDS             complement(51104..52030)
                     /locus_tag="VW883_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0273469.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(52023..52715)
                     /gene="ftsE"
                     /locus_tag="VW883_000273"
     CDS             complement(52023..52715)
                     /gene="ftsE"
                     /locus_tag="VW883_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0273470.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKKRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(52733..53828)
                     /gene="prfB"
                     /locus_tag="VW883_000274"
     CDS             complement(join(52733..53755,53757..53828))
                     /gene="prfB"
                     /locus_tag="VW883_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0273471.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(53936..54592)
                     /locus_tag="VW883_000275"
     CDS             complement(53936..54592)
                     /locus_tag="VW883_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0273472.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKIKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(54900..55610)
                     /locus_tag="VW883_000276"
     CDS             complement(54900..55610)
                     /locus_tag="VW883_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273473.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(55610..56374)
                     /locus_tag="VW883_000277"
     CDS             complement(55610..56374)
                     /locus_tag="VW883_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273474.1"
                     /translation="MTLLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLAGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(56374..57330)
                     /locus_tag="VW883_000278"
     CDS             complement(56374..57330)
                     /locus_tag="VW883_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0273475.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGATVSAIVLGILNMLLQDVTS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(57334..58203)
                     /locus_tag="VW883_000279"
     CDS             complement(57334..58203)
                     /locus_tag="VW883_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0273476.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLVTAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(58471..59631)
                     /locus_tag="VW883_000280"
     CDS             complement(58471..59631)
                     /locus_tag="VW883_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0273477.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(59732..59980)
                     /locus_tag="VW883_000281"
     CDS             complement(59732..59980)
                     /locus_tag="VW883_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0273478.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(60059..60649)
                     /gene="clpP"
                     /locus_tag="VW883_000282"
     CDS             complement(60059..60649)
                     /gene="clpP"
                     /locus_tag="VW883_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0273479.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(60823..61452)
                     /gene="upp"
                     /locus_tag="VW883_000283"
     CDS             complement(60823..61452)
                     /gene="upp"
                     /locus_tag="VW883_000283"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0273480.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(61541..62008)
                     /locus_tag="VW883_000284"
     CDS             complement(61541..62008)
                     /locus_tag="VW883_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0273481.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(62027..62584)
                     /locus_tag="VW883_000285"
     CDS             complement(62027..62584)
                     /locus_tag="VW883_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0273482.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            62709..63554
                     /locus_tag="VW883_000286"
     CDS             62709..63554
                     /locus_tag="VW883_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0273483.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            63613..64785
                     /locus_tag="VW883_000287"
     CDS             63613..64785
                     /locus_tag="VW883_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0273484.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGANPI"
     gene            64800..65045
                     /locus_tag="VW883_000288"
     CDS             64800..65045
                     /locus_tag="VW883_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0273485.1"
                     /translation="MEQSPQKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
BASE COUNT        19296 a        14197 c        11762 g        19820 t
ORIGIN      
        1 aatagcgaga aatatctatc ctatcttcta gaatgtcttc caaacgagaa aactctcgta
       61 aacaaagagg ttttagaggc ctatttaccg tggactaaag ttgtacaaga aaagtgtaaa
      121 taagaaatct ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatag
      181 acttcgttat tggacggtta ccaagttact caaagtacag atttgaagct gcagataaga
      241 ctgacgaaat cactttaata ctaaatgaaa atcaaaaagc aaactaagag cctcaggctg
      301 tacttgagta cggtaaggcg acgctgacgt gatttgaaga gattttcgaa gagtataaaa
      361 cactgttttg aggtggtgga taaatcggct gggcaaaaac tcaatctcag gagaaaatga
      421 agtaaatctc cccacaacta tagaaaaaga tttgattctg ctcctcacac aataaaatct
      481 ttttctttta ttaaaaacga atcgtttcac gtgttttctc atatgaggta acaaagcgat
      541 tggttacacc aggctctgcc acttccaatg cttgagaaat cttgtcaaat gaagcgtgat
      601 aatcaaattc tttttcaaaa atatctaaag cttcgttaaa tgcttcttga atgcgttcat
      661 caaatgagcg atagcggtta gaatattgta agagttgctc tgtcaaagtt gcatattgta
      721 caatattata agtttccgtt tctaaagctt ccatatcatt cgttgcaatt tcaagaactc
      781 gggtaacaga ttcaatgtta atcatttttt gttctaactc aaccattaaa tcctcggtat
      841 tattgcttgc cgtaaagaat aacttcaaga aagtttgtgg aatacctggc agattgcgtt
      901 tttccatgta tcgcttgata gtatggagac gattgacata aacattggcc ttttgacgtg
      961 cattaatatc atctttctca atttgtgtca ggcgctcact aactgaaatt tgctcatctt
     1021 caatatcttt tagttgagtt tgtaaatcct caagattttc ttcaagaact gaataagctt
     1081 gggttggttc ttcttgattt gaagttacct caacaatagc tgcctcaaaa ctctctaatt
     1141 ctgtctgaat acgacgaaca tggcttgcag ctgtctcagg aagtaaatag gtcttgttca
     1201 aacgtgcaat atcttccccc aataaagtat tattctcttt catatgttga agataagttg
     1261 gaagagttgc aagtagattt tccactactt tctgagcagc aatttctcga gtaaaaatat
     1321 catacaaggc attgatttcc tcttgtgcct gtccattctc atattcggca ttatccaatt
     1381 ccaactgacg aatattctct tggtttttct tgaatgcttc ataaagcaag tggaaacgcg
     1441 cttcaatatc cgtttcaaca aaatgataat tagcatcaat tagtttacga taaccggctt
     1501 ccaaatcctg taattgatct ggcaattctg tagaaagcgt cgtaaccaag gctggaacac
     1561 gatccacaat atgacttaag gccaaaatgt gattttctgt attatccaaa atcactgcgg
     1621 cttccacagg gtcacccgat gaattcaagg ttacaaattg tgaaaattca gattggatat
     1681 tttctaattg tttttcaatt tcatccaagg cttgaccata ctgttctgaa ttttcagcaa
     1741 ctctatgctg aagttcctca aataaatcca aagcatgaag aacacgacca ctatttttag
     1801 attcttgctt ctctaagtct gccaaagcat tgcgaattgc cgcaatatct tcttcaatca
     1861 aagtaatttg actctcaatt tggtcaattt gatgactggc cttgagaaaa cgaaatgaat
     1921 ggttatagcc ttctgcttca aagagattat tttcaatatc ggcaaaagag ttgagagata
     1981 aatcgaccca tttttgattc cattcacgga aagccacttg actttgtcca atcaagtgca
     2041 tattttttac agcttctact tcatcattta ctggaagatt gtatagttct tcttttcttt
     2101 cttctagcgc ctctaatctc ccctcgtttc gcttacgtag aaagattgcc actacataag
     2161 ccagaactaa aatgactgca attgcaacca ttaaataaat tagttgtcca ttagacatat
     2221 caaactcctt ttttacttga aacaatcgta acgattatat catatttttt agaccaaggg
     2281 aactacttct ccctattttt tagacatcaa gtgtactata gacagcattt tcttcgataa
     2341 actcacgacg aggctctact cgatccccca tcaacatatc aaagatttta tctgcttctg
     2401 cagcatcatc tacagaaact ctagccatca agcgatgttc gggatccatg gttgtttccc
     2461 acagctgatg atcgtccatt tcacctagcc ccttataacg ctgaatagtc ggtttggtac
     2521 gaccttcact ataacgggct aaagcttctt ggagtttgat ttcttgatct gcacccggct
     2581 ggatatattc tttaatctcg cttccaacct tgacaccata gattggtggt tgggcaatat
     2641 aaacataacc agcttctagg attggtttca tataacgata aatcaaggtt aaaagaaggg
     2701 tacgaatgtg ggctccatcg acatcggcat cggtcatcaa aacgagtttt tggtaacggg
     2761 ctttcgaaac atcaaattct gcgccaaatc ctgttcccat ggctgtgaaa agactacgaa
     2821 tttcttcgtt agctagaatc ttatccatac ttgctttttc aacgttcaaa atcttaccgc
     2881 gaattggaag gatagcctga aactcacggt tacgaccaga tttggctgat ccaccagctg
     2941 agtctccttc gacgatgaag agttctgttt cagcagggtt attagaagaa cagtctgcta
     3001 gtttccctgg aaggttggaa atttccaaac cagatttttt acgtgtgact tcacgcgcac
     3061 gcttggcagc cacacgagcc ttggcagcta aaatcccttt ttccacgata cgtttggcaa
     3121 tctgtggatt ttccatgagg aaatcggaga aggcttcact gaagaggcga ttggtaatct
     3181 tgaccacttc gctatttccc aatttggtct tggtttgtcc ttcaaactgt ggatttgggt
     3241 gtttaactga gataactgca gttaagcctt cgcgaacatc ttcccctgtt aaattatctt
     3301 cattgtcttt cagtaactta ttcttacgag cataatcatt gataacacga gtcagtgccg
     3361 tacggaaacc ttgttcatgc gttccacctt catgggtatg aatattattg gcgaaactca
     3421 tgacattttc atggtaacct gttgtgtact gcatggctac ctcaactgta atatcatcca
     3481 tctcaccgtc tgtatagatt ggtgtatcaa agattacatc cttgttctcg ttgatatatt
     3541 caacgtaact agcaatccca ccttcataat gataatgctt ggtttgttcc aaaccttggc
     3601 gcttatcagt gatagaaatt tgaagaccgc gatttagaaa ggccaactct tgaatccgtt
     3661 tatttaattt atcaaaatca aaggttgttg tttcagtaaa gatttttggg tccggtatga
     3721 agtgaaccgt tgttccagtt ctatctgtat ccccaaccac ctcaaggtct gcaacaacat
     3781 gaccacgacg gtattcttgg taatgaatct taccgttttt atggacatga acgtctaatt
     3841 gagtggaaag ggcattaact actgacgacc ccaccccgtg aagaccacct gaaaccttgt
     3901 atccaccacc gccgaacttt cctccagcat gaaggactgt aaagacggtc tcaacagcag
     3961 gacggcctgt tttttcctga atatcgactg ggataccacg cccatcatcc acaacagtaa
     4021 tcgaatcatc tggctcaata aaaacttgaa tatggctggc aaatcctgcc aaggcctcgt
     4081 caattgagtt atcaacaatt tcccagacta gatggtgaag accttctttt gaggttgatc
     4141 caatgtacat ccctggacgc atacgaacag cctctaagcc ctctaaaact tgaatttgac
     4201 tggcatcata atcctgtgcc tgcagatttt tgatttcttc tgtcatctta ttcctttttc
     4261 ttatatgtct aatacttgtc ttaaattcac gatactggta aacaagtggg tatcaagtcc
     4321 tgcagcttga cctgcttcga tatcaatcgg ccgatcacca atgacaagac cagagctaat
     4381 ctgatacttt tctcttaaat aaagcatgga ttcgggattt ggctttctct taaagcctga
     4441 gctagaagtc accacttctg taaaataagc tgctatagag gttttttcta aaatttccaa
     4501 aacctgatca tttcgatgag agaccaaaaa atgacggcca ccttgatttg aaatgacttc
     4561 caataggtca gaaactcctt caaataaaat cgggtgttca agctctctgg cttcattttc
     4621 cttgtacttt tctaaaaaat tctctaaatt gggagcgaat gtctcaatcg caaaaggagt
     4681 agaaaccttt aaagcttgat agacactgtc atggtcttgt gtgataccat acagtgccaa
     4741 tgtttcaaca aatgcagctg ttgaagtttc ataattatcc agtaaagttc cacctaaatc
     4801 ccagatgtaa tcgtgatatt tcataccctt cattatagca tttttttatg aaaaaagcga
     4861 tgatttccct gagttttcca cataaaaaac gagagaataa ctcccgtttt actgattttt
     4921 accaaagaca tctcgataga gcattcctgt tcgtaaactc tctgcgtccc ctcctagttg
     4981 ctccactaac tcgtaggcaa aggcaagggc tgttgaagga ccccgactgg ttgtcaactg
     5041 accatctacc actactgttt ccttgacgta gtgaccatca aggatttgct cttgaacgcc
     5101 gtcataacaa gtgtatcgct tatttttcaa tatctctgct tgattgaggg caattggtgc
     5161 cgcacaaatg gctgctagtt tcttcccttc ttgctcgaag ctttgcaatt cttgaatcaa
     5221 ggtctgatta tcacgtaaat gtgcagaacc aggcatacct ccaggaagaa caatcatatc
     5281 atagtctgat aaatctccat caaagacatg atctgctctt acttggattg catgcgaacc
     5341 cgttacttgc tcttcaaaac caaccatatc acatgtgata ttggctcgac gcaagacatc
     5401 tacaactgtc aaggcttcaa tttcttcaaa gccctgagct aacataactg ctacttttac
     5461 catgattttc tccttattta atttgtttta atacaacctt tttccgtttg aatgggactt
     5521 ttccgctctt ttcttcagct agattagtct ggtaactcat cgataaaagc aaaccaacac
     5581 caatcagatt actgataata gctgatcccc cttgcgaaat gaaaggcaag ggaatccccg
     5641 tcaaaggaag tagtccagtc acagcaccga tattctcaaa gatgtggaag agcaacatca
     5701 taatcaaacc tgtggaaata taagtgtaga actggttatt tgatttaaga gtaatcttca
     5761 acatacggta aatcaacatg agatagaggg caataaccag gacagagcca ataaagccaa
     5821 aatcttctgc aataaccgta aaaatcatat ctgactctcg aactgggata agcagattcg
     5881 aagcattaaa tccctgacca aataagccac cactcccaat ggcaatctgc ccttgagcct
     5941 gctggtaagt cgttgtttgg gcaaactcaa agggattgag ccaagccaaa atccgattaa
     6001 tttggtaggt cggcattcca atctggtgaa gaaaagctcg tccgtccttg ctaataaaga
     6061 tagctaagaa accagcaact cctgttacag cagtcacaaa tactgggata ataattttcc
     6121 aagaaacccc tgataataaa acgattcctg agaaaatggc tacaaaaacc aaagccgtcc
     6181 ccaagtcact ttgaagtgct aaaagaacta ggactggaat ggtaaagaga atcatccaga
     6241 aaattaacaa aaagtccagc ggaaccgtgc gtctccattc cttatgtttc tttgtaaatt
     6301 ggacaatgac acgagccaac atgaggatat aggatatctt cataaattct gacggttgga
     6361 atagggtaat tccatttatt gatacccagt ttttggcacc cgttgatgca actaagcttg
     6421 gattataaaa tacaatcggc aagatcataa gtcccaagcc taaaatatat agaaaggggg
     6481 tcaccttcca aagaaattct gtattaaaga gcatgaccac aaaaccaatc acaagcccca
     6541 aggcaatcca ggcgacctgc tgccctaaaa tgggcagaat attattggga taatcatgac
     6601 taacggctat atagatagcc accacaccga tgaccagtag aaaaaatact ggcaagagca
     6661 aactataatc gactctagag tcgagagaac gtttcatata tactaacctt atactttcat
     6721 acaatactat ttatcaaagc tcattaaaaa atctatcaat agcctcgtca acttcggatc
     6781 gagagatggt tttaacagtc gcttcttctg ctagagatgc tactatttgt ttgccgtatc
     6841 gttttccgac gattctccta tccaaaataa gagttaagga acgttggtat tcacgtctca
     6901 tacttcttcc caaagcctgt tttaaacgaa taatggccat tggcaattga taatcataaa
     6961 aggcattttt cccttcttga ttcagttctt gattaatctt tttcgtcaag ggttcttgag
     7021 gattttggaa aggaagcctc ggtacaactt gaatcacaga aggatggctt gaaaaatcaa
     7081 ctccctccca gaaacttgct gcaccaagca agatttgttg ttcacctttt tcaaagcgtt
     7141 tctttagctg atgaacatcc ccatttttat actgggccaa gtggctaact gtaagtaaat
     7201 ccgatactgc tagaagcatg tctttagcgg taaagagaac caaaatcggt tgctggaaag
     7261 cttgaatttc cactagtaaa gcagctacct ctctggcata gacttctaag gaggtttctg
     7321 ttaccagagg gaaatctttg accatgacca cttcttgttc ctgttttccc cgagattcaa
     7381 tcttgacaaa tttagcttca ggatagccta aaaggtctgc caaagaaacc ctctgactaa
     7441 tctcaagagt agccgatact cccaagactt ggcaactctc aggaagtaaa gaggacagaa
     7501 gagtacggcc tgattttgta gaagaaatct gaattttctt ttgactcgtt tcagttactt
     7561 caagccagta atcaccttca gctgtaaaat agcgaaccag ctcatcaaag tcttctactt
     7621 ccaattctga aaaatactga tggagattgt ccagagaatc taagatattt ttcctagatt
     7681 tgccagactg aaattgttct atcaagtaga gacactcaaa gcgaatactt tctagtatcc
     7741 gttgttgaac cctgttttct tctcctacta aagccttatc aattaaatcg ataatagatt
     7801 gtatatcgta ggtctcttga agcagatttt ctagagctaa caaaatcttt tggacttcat
     7861 caataatcag taaacggtca ctgacaaatt caggattatc ttcaagtctg gttacgagat
     7921 aggcatgatt agtcactaaa agcttgcaag tctctgccct ttcttgacta cgtttccaaa
     7981 aatcttccgt cacaaataag ctctgggatg ataaattccc atcatgacga aggtctgcta
     8041 gaaaatgttg gtaacggtag agttgcccga tttcatccaa atctcctgtc tctgtctcag
     8101 taagccagac caagacttgc attttaaagc gtctaaataa gcgattttca tcattttcct
     8161 gcaaggaatg ataaaaggca tccaacttca gataattttg tggtcccttt aagctatgaa
     8221 tatctgtatg gaacacttcc ttgaggcgtt taccttcttc ttccatgatt tgattttgaa
     8281 gaatctttgt cggaacacta agaacaattt gtcgctcttt ggattgagat aaagcgggta
     8341 agagatagcc ataggttttc ccaatccctg tcggcgcttg aatcagagag acaggttcat
     8401 ctttcaatag caagccaacc tctttagcaa aactttcttg ttcctccctc acttcaaggt
     8461 tcaacagaga aatattttta gaaaagtctt gagatagttt tcgtggctcc agagaagctt
     8521 ccgttttctt aaaatataga ccttgaactt ggaccaagtc tggagaactc aggatagatt
     8581 ggttgcgata agtttcctca ataaccaggt aggactcata taggagagcg tcagccattt
     8641 ccagcaagcg ttccaagaga cctttaggaa gctgggtcat ctttttccgt aaaaaaagaa
     8701 gtaattctgc tgtagcttgg gcatctgaaa gggctgtgtg tgcgtgttta agaggaattc
     8761 ctaattctcg acacaaaatc ggcaaactat atttttccag ttcagggaaa aagacctggg
     8821 ccaattcgac cgtatcaaca cgagggtttc ttagctcata gccttcaaaa aataaatttt
     8881 ccgccaagag attagcatca aactgaacat tatgggctac aaaaatccca tcctccacca
     8941 agtcaaatat ttttctggca acttgcgaaa aatcaggtgc ttgcgccaga cgttggtctg
     9001 tcaatcctgt cagttctttg atatgagcat ccaagggttc atgtggattg acatccgtcg
     9061 tatagtgatc gacgatttct ccgtcctcaa tcacgacaat tcccacttgg ataattttag
     9121 ccttactacc tgtgctagtt gcctctaaat ccaccacaac atagcgatta ccaatcgttt
     9181 tcattataaa aaattatacc aaaaaaaggg ccatttggca cctgcaaaca taggataatt
     9241 ttcaaactca agaacactac ttttcttaaa aatcccatcg aatagagcat tctagcctgc
     9301 tgatttttgt aaaatagtga agaaatacga aaaattgaga gaagaaatgt ttgcatcttc
     9361 cttctctcaa cgaatcatgt attttatcta accatgtcag gatcgtagtc ataaaatcct
     9421 gtatcaagga aacggttttt agggtgaagt ttacgaactt cttcatccag caagaaggct
     9481 tgagcatgac taaagttgcc ctcttgaatc aagctacgcg cttggataaa gagttttgca
     9541 atctcaacaa agttctgacc aggagtgtag agcccttcta gtttccagcg agtaaagcca
     9601 tgctccacca attctgttaa tttgatcatc aaatcaaggt cattgttggc aaagatatgg
     9661 gtcccatgat tatcttcaaa aatggaatag tggctctctg gatcacttgg ctcagccaag
     9721 aagaggtcac gtttatgcgt cttttcatca tcgatatgtg taaagttata gtagttttgc
     9781 aagagtggac gtttagaatg atggatgacg ctagcaccgt aaaccaaaac ttcagcagga
     9841 atttccaaaa tctctggcat tttgaaaagt tcagctgatg gaatttcacg cgccaaaaca
     9901 gcctcagatg cgccagcctt ttgtccccag aagttaatct gacgactgct agttaccatg
     9961 gttgaagcat cgtagatggt cttaaatgaa taaccatcgc ggttaactac gtaaaagacg
    10021 cctgcatccc caatcgtaat atagtctgtc ttgatttctt ccaagaagtc taagaaaggc
    10081 ttgatacggt ccatcatatc ttggtgcatg agagcattga ccgcaacgat caattcctta
    10141 ccagcatcat gaaccaactt agcgatttca cgtaattggt cataactaaa ggtcgttggc
    10201 agacgaagac caaaatcttt ctcaccgaca tagatacggt ctacgccagc ttcgagtagt
    10261 tgttcaactt gttcaatact ttcagcagtt gctgtaatga caatcttttc cataagaaaa
    10321 attataccac atttctccaa aatcagccat gctttgaaaa tgaaaaggga ctttattctt
    10381 tttgtaacct ttctgtaata attctctgcc gaaaaaatga taaaataggt atgtactgtt
    10441 aaggagagaa tcatgcccgt aagaaaatta caatcctatg aggtagacta tcaagaagaa
    10501 ttaaaccagc agcttcctca ttaccaagct tatacacctg aagcgcaatc tgatgccaat
    10561 ctcaaggaaa tcctattttt tattaatatc gctgtttttt gtatctgtat tgctatcttt
    10621 agttttatct ttttagcatt aaaattatca actgctcttg cctttgccgc agcaatcgga
    10681 ttcagcttac ttgttttaaa agttcaacgg tctattatca aacgaaaacg tagaagataa
    10741 atccaaaata tcgccccaat tggagcgata tttttatttt ttctttttag atggtgtctg
    10801 aatggcaatc ttcacttcaa agattgttcc cttgggttta ttatctttga cagtaacagt
    10861 tccttttaga gcatctacaa tttgcttggc tagggataat cctaaaccaa aaccaccttt
    10921 ttgccgggtt ctagccttgt ctactcgata aaaacggtca aaaattttct ttttatcttc
    10981 tgtcgaaata ccgattccat tatcagaaac aagtaaataa agattgcgat cggtcgccga
    11041 gataagaaaa tcaatttcac catcctcctc agtatacttg acggcattat cgaaaagaat
    11101 ggtcatcagt tgtttcagaa gaagctgatc tgtgacaatt gttcgatgga tacgattttc
    11161 aaaacggaag acacgattat tttccgaagc aatcatctca tagtttgtga aagttgtatt
    11221 aaaaaagcta gttggaactt ctgcaagctc cggcttaatc ccatcatctc tccgagctaa
    11281 gttcagcaag cttgtcgtta aaaaacgcat atttcggact tcttccaaac tcgatgcaat
    11341 gctttcgctc acatccataa tggtagcttc tggcttacga aaaagggtct ctaagcgatt
    11401 ttgcaaaact gcgagtggag ttcgtaactc atgactggca ttttccacaa aagactgttg
    11461 cttctgcata ctctcaagca ggggcctaac actgacccta gctagataga gactggcaag
    11521 taaagacaaa atccagaaac tagccatcac gaccacaatc aattgctcat gcttttgact
    11581 agcctgctcc aactgactgg tattaatcaa gacagcagca tacttgatat tggttgaaac
    11641 cgaactaata ttggtctcca tcaaaatcac acgatagatt tcttcctgcc catagctatt
    11701 aaaaacctga atctggtaga tatgtcctag ttctttcttt tctaacttaa tcttatccaa
    11761 gcccaaaaat cgatttccag aaagaagttg agtaaagtct ttatcaaaga gaatgacttc
    11821 cgtattggaa ctgacattag gttttatttc tactttacta gcgtccgccc tagcattttc
    11881 taaatcttta atctcttctg ttgccctatt tatagccagc tgaataactg cttgaggatt
    11941 ttcactcagt ccatgaagct tatcgtccac cgaagtataa agactcgaat gcatgacttg
    12001 taaaataatc agagtcattg tagaaaaaat cagggtgaag acaccgaagt tgcggataaa
    12061 ataactaaag tcatccgcat accatgtttt tttaagttta ctgaacatct tttaaaagat
    12121 acccaacact acgcaaagtt tgcaaattct ctgcaaaagt ggttcccttt aatttcttac
    12181 ggacttttga aacatagact tcgacaaccg aaatcgttgt atcactatca aatccccata
    12241 gacggtcaaa aatctgcgtc ttaggcaaaa tcacattttg attttgaagg aaataaacta
    12301 gtaagtcgaa ctctttcccc agcaattcga caggagtatc ttcaacttta acggtattgg
    12361 ttgataaatt aaccacgata ttcccataag tcaaggtgtt ttcattaaac ttccctgaac
    12421 gtttgagaag ggcctgaatc cgcattttaa gttcttctag gtagaaaggt ttggtcagat
    12481 aatcatccgc tcccagttca aatccatgtc ccttgtcatc caaactttcc ttggcagtca
    12541 taatcagaac tggtgtcgta attccctttt cacgcaattc ttttaagact tggaaaccat
    12601 ttttttctgg caacatcaaa tccagcaaaa tcaagtcata gacaccactc tcagcttcgt
    12661 agagaccttc ttctccatca aatacctgca taacatccgc aaaatcgtct aaaaagtcaa
    12721 atactgaatt tgacagacct aggtcatcct caaccaataa gatttttatc atgagaaact
    12781 cctccttatt aaaactatta taccaaattt gccttaaaaa aaaactcaac tctctgcatt
    12841 ttacatgaga tagctgagtt ttctttttat tttaggctta tttatgcatt tccgtattga
    12901 agaacaactg cttcgactgc agctttttca cggctaatca agtcaacacg tgctgcaatt
    12961 tccttgattc ccataccgat gttacggcta agagcaaggt cagaaagttg cggctcaaag
    13021 aactccttgt attccgccaa gcgttgctga gtcttaaata catgagcagg aaggataaca
    13081 aagctatcaa agctcatatc tcctccaagg gctgccttaa tccaagccca gttttcacgc
    13141 gcccaagacc aagctgtttt ctgagttgct tgatgagcta ggaattggta ataccaagca
    13201 gacaagtcct gtggtttgac cacaaatttg tccttccaag aagtaatcag gttttggata
    13261 ttatccgcat ctgtactgta tgcaagagct gctgccaact ggcgtttaaa gacagcatct
    13321 gttgcgtgag tataagtatc aagataaagt gctaacaagt ctttagtctc atgatgtttc
    13381 atctcattaa tcagaacttg tgagcgaata gctgctggga gtcctgcaag attctccttg
    13441 tgtgttgcga agatttggct agcgacttga ctagcttctg catcatttga gcgaatcatc
    13501 atcgaaacag ccagctgacg aaccaattca tcctcatctg attctccgtc tttagcttca
    13561 aaaccaagac ggtcatagtt atgacgagcc aatttagcaa ccagtccttt gaaggctgtt
    13621 tcagcatccg ttccttcatc aataaagcgc tcaagggctg aaatcacttg agaaacagct
    13681 gaaaccacca gataagactc ttccttagca agtttatcaa gaactggaag caagtctgca
    13741 taagaaatgt gccctgcctc agccaacaaa cgacgttctt gaacaatttg cagtttgctt
    13801 gtgttatcaa gtgtctctag ctcagcaaga acagcttcta acaagtctcc ttgatagtcg
    13861 gtaatatagt gggcagtatt ttcagtgttg agacgaagag ctccttcatt ttcagcaaga
    13921 agagctgcgt agccagggat ttcgatactt tcagtttcga gtgtatcagg caagcctttc
    13981 cagttgctat tgaggggcac cacccagaga cggttcttgt cttcgttctc accgatgaag
    14041 aattgttttt gtgaaatctt caagacatca ttttcaactt tgacagtaag aactgggtaa
    14101 ccaggctgtt ccaaccaaga atccatgaag gctgcgacat cacgtcctga cgcttgacca
    14161 agggcatccc aaaggtcact accaatggtg ttgctgtatt ggtgtttttc aaagtaggcg
    14221 tgcaaacctt tagcaaaatc agcatctcct agccaacggc gaagcatgtg catgagacgg
    14281 cttcctttgg catagacgat agcgccgtca aagagtgtat tgatttcatc tggatgttta
    14341 acttcgacgt ggacagactg aacgccatca gtagcgtcac gttcaagagc aagaggtact
    14401 ccacctgttt ggaaatcttc aaagatattc cagcttggtt cgatggtatc cacacagacg
    14461 tattccatca tattagcgaa actttcattg agccaaaggt catcccacca tttcatagtc
    14521 acgaggttcc caaaccattg gtgagccaat tcatgggcca caacaagggc aacttgttga
    14581 cggctagcaa atgtagagtt ctcatcgaca accaagtaaa cttcacggta ggtcacaaga
    14641 ccccagtttt ccatagcacc agctgagaag tcaggaaggg cgatgtggag agattgagga
    14701 attggatact taactccata gtaatcttcg taaaactcga tagagcgaac agcgatatcc
    14761 agtgagaaat caagatttga aagtggatgt gctttggttg agtagacacc taccagggta
    14821 ccatttttag ttttagcggt caccccttgc aaatcaccag caacaaaggc caacaagtaa
    14881 gaagacatgc gaggtgttgt ctcaaacttc cagatacctg tttccttacg gttttcaaca
    14941 tcgatttctg gcatgtttga caaggccaat tcaccttctg cttggtcaaa gcgaagagag
    15001 aggtcaaaag ttgctttggc ttcaggctca tccacacatg ggaaagcttc gcgcgcaaaa
    15061 tggctctcga actgagtaga caagacctcc ttcttgactc catcaactgt ataataagaa
    15121 gggtaaatcc ctgtcatgtt gtctgtaatt ttaccagaaa aggcaagaac caattcaact
    15181 tgaccagcct cagccaattc gatatgaagg gcttcattgt catggtcaac tgtaaatgga
    15241 cgagcttgac ctgcaacttc tacagaggtg atttccaagt ctttttggtg gagggagatg
    15301 cggtcactct gtgcttgacc agtgatggtc actttcccag aaaaagtctt ggtctcacga
    15361 ctcaaatcta aaaataaatc ataatgttca ggaacaaatt gcttaataaa atgttcaact
    15421 gcttgcatag ttttctccta ttctaagttt aagagctgct gctcttcttc aaacaaactt
    15481 attatatcat attttgcttg agaaaaaagg attggacagc gatttccaaa actttcttcc
    15541 ttctaatagt ctacagtggg tagaccttgc gaaattcttc taaaacaacc ttgctttcag
    15601 atgtaaaagt cagccctact tcacccaaac agtctgtgaa aaagtcctca tgaacctggc
    15661 gccaataggc aagtgatttg tctccctcac cttccttaaa ggcatgttgc gcagaaactt
    15721 gattgaagag ttcaacagaa acctttgtaa tttcgacaac gcagacagcc tgattttgac
    15781 tatctaaaat gacatcgaag gtccctactt ggggaagtgg ttcgtcttct agtacataga
    15841 ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa caccaaatcc gctaaaaggt
    15901 ctggttcaac tccaaaagcc caagcatcga tttcatctcc gatcaaagga ttgatttgct
    15961 tgtatttatt ccacatttct tgcggtatca tgggtactcc tttgtaattt tttactttct
    16021 tcttttatgt gtttaagatg atctggatgg tcaatctcta aatcaaaaat ctctggaata
    16081 gaactgtagt ggataatgca cttgataccc aactgattca ttttttgtat gaaagaagta
    16141 ttcagatagc ctgctacagc aaaattaatc ttgttctttc ttgctttatc ctgcatatct
    16201 cttagcatat ctaacattat tggactttcc atatcatgcc attgactgtt tctcatagtc
    16261 gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa tctttgaaat gcccgtttcc
    16321 agtatactag ataagtcaaa atacgctgac ggtaattcaa tcatcgttcc gactttccca
    16381 gtaaagccat actgacgcaa tactgtaata gcttgtttta attggtcggc atcattgaca
    16441 aaaggaaaaa taagagacag attgggattg gtttgataaa cttctgtaac gacatgtgat
    16501 tcagcctgaa attcatccaa acacgccagt aaacgcctgg ttcctctata gccaaacaag
    16561 ggatgccctt cgtcaaaaaa ctctctagtc cccgctaaac aattggcttc tgtattcgtt
    16621 aattcagaaa aacgatacca aacttcctta tctaagtaaa aggagcaaat agtatcaaga
    16681 taatctttta caaattgctg acaacttgct aatatgatgt tttgattaag ctctctcaat
    16741 aagtattccc cacgaatcat gccgacgtgg tgaaatagtt gaggataaat tttttcaaga
    16801 attttttcgc cactaagggc aagttgattt ctcatagcca ttcacctcgt cttaaaagat
    16861 acaatatcat atataattat atcaaaattt cctctagttc aaaagcttca taaggttcag
    16921 ataactcata tcctaaaaat tctgctactt ttttggaagc ctcattatga gcatcccaaa
    16981 gtggaaacat atctctattt aaactctcta gaatcattgc agcaccaagc tttttagcaa
    17041 atccatttcc ttgttcgttt ggtctagttg caacttccac ttcaactgct ttacggtaaa
    17101 ctaaccctga ggaaatccca gcaatcagtt cattattttt aagaatcaca aagccaaatc
    17161 caccttttaa aacaaaatcc tgataggact caaaatcccc ctgtaaatcc tgtgaccatt
    17221 cttccgtaga aaagcagtta taaatatgat tatcaatagg cacaatattg taaccttcct
    17281 ctaaatgagt aactagatta tttaaaaatt caacttgaaa atttgcctta tctttaaaag
    17341 aatagcgagt aaaagaattt agccccactt ttcgatgcag aaaatcttgc caattagtat
    17401 tttctgaaat aataatctta taatctaaac catattttct aacaaaatct tcccaaaatc
    17461 tggaatccaa ctcccctgct aggtatagaa aattcccaac atcataaaag cttgttgtcc
    17521 tatcattgtt tcggtagaca gttccaattt gagatttaag accatagaga accatatttt
    17581 tcttccatgt tttaaatagt tccattatcc ctctacttca ccttccaatt catgtaagaa
    17641 gtcttgtcca gttctggaaa tcctaataat tcagacttaa ccttcaagac taatggcgat
    17701 gcattttctt ctgtaatctc ttgaatatcc atccaaatat atccaagtga atcattcgca
    17761 ccatcagaca cagcttccga agtcgtaact tgaggtgcac tctcattcat ttcaacatca
    17821 tacaaggcca tgacatggtg aaccataaaa tttgttaact cttctctgac gaaaacatcg
    17881 tagattcgag gattagagta gcttctaaca gtaaatcccg tctcttccat aacttctcta
    17941 gtcagcgttt ccgtcagtcc ttcaccaagt tgctgactgc ctccaggtag atcataccga
    18001 tgttgataag ggcctctcgc tttttcaatg cagagtaact tcccattttc taagcaaaca
    18061 gcgtagactc caaagtgttt tttgatttcc atccaactcc tcctacttca aagaccagcc
    18121 accatctatt gtcaagattt gtccttgcat ggcgctcgct tttccacttg ctaaaaaaag
    18181 actaagctct gctatttcct ctggctcaat ccagcgcttg attggggttt cactagccac
    18241 ccagtcagcc aaaccacctg gttcaaaatc cgcagcggtc atagctgtct tgactgctcc
    18301 tggagcgatc ccaaagacct gaatcccagc ttcagcatag tctagagcca actgcttggt
    18361 gaagccagcc aaggcatgct tggatgaagt ataggcgtga ccacctccac ctgctaggct
    18421 agaagcaatg gaacacatat tgatgatgat tcccttttta ttttccagca tttgtgtcaa
    18481 ataataccga gtcaactcta ctggaataat gtagttgatt tcaaaaatct cttgaatgtc
    18541 ctgcgccgtt tgttccaaca gtggtttgta atcatccaaa actccggcag tattacacaa
    18601 aacatccacc tgagggcacc agtcaaaaat aggttccaag tccaaggtca aatctctctg
    18661 taaaaagtga aaatcaccct ctaagagtgg cttttcacct tggtcaactc cataaacttg
    18721 atagcccttc tctaaaaaga ggcgagcttg agccaatccg atccctgaac tcactcctgt
    18781 aatgagtaca cgtttagtca tgcacttcta cccaatccgt tgccaaaaca tcacaagctg
    18841 tcgggctcca catggaaaaa ccttctcctt ctccagacac gttgattagg aaataaggtg
    18901 tcatttcaag tgcaagccca ttttgctcga tggtatcaaa gagttggaca tagttttccg
    18961 cacctcccca accagttcgt acatattttc tcttagcctt taacccaggc aggatctctt
    19021 caaatgtcat gtttttctcc tttaattcta cattcttcat ttaattataa caaaaaaacc
    19081 gctttaatac ggctttttga ctgtgattta tttacatctt cttctactta cggcaaatta
    19141 ttccctgcag caagataaat ttcataccat tcttttcttg ttaagctaaa gtttgccgct
    19201 tggctaactt ctctcaagtg cttaggattt gtggtaccta caactgcctg catttttgct
    19261 ggataacgca atatccaaga aatggcaata gttgaagagg ttactccata tttaatagct
    19321 aaacgatcaa gtacttgatt taaagcttga aatttctcat ttccaacaaa attcccttta
    19381 aaatacccga attgcaagac agaccatgct tgaatgacca catcgtgtaa ttggcaatat
    19441 tcaaaaatgc tgccatctcg catagctgct tgactatctt ccatattaac atgaaaagct
    19501 gattcaaatc ctggagtaaa agccgcactc aattgtagct gattaacagc taacggctgc
    19561 ttgacatctt ttttaagcaa ctccatcatc ataggatttt gattagaaac tccaaaatct
    19621 cgaactttac cttgtttata aaggagatta aaggcttctg ctacttggtc agattccatc
    19681 aaagcatctg gtcgatgaag gagcaagcta tctagatgat caatcttcaa tctttgcaaa
    19741 ataccgtcta ctgattttat aatatagtcc ttagaaaaat caaaataggt aaattcttca
    19801 atgcgaatgc cacatttgga ctgaatccac atcttttctc ttaaatctga acgatttttt
    19861 aggacaagac ctaacagttc ttcacaacga ccacgaccat aaatatcagc caagtcgaag
    19921 gcattgattc caacagaaag tgctgtttct acaagctctt caacttcttt tacagactta
    19981 tcttttattc tcatcattcc gagaacaatt tctgataatt ctttgtcatc ttgaccaaga
    20041 gttatgtatc tcatcaaatt tttctccttt aatttctaac attcttccct tcattataac
    20101 aaaaaaccgc tttgcaacgg ctttttgact atacttcact ccattttatc ttcttaaacc
    20161 cacggaacaa gacaaagatt ccaataaaga gaacagctaa aggaataact tttgtaagga
    20221 aaacatttga aattcccatc cactcataat aacggagcag agaacccacc acaagatggg
    20281 caataatcat actgacaaat ggacgaaaga ccgcttcttt ccaattccaa ataccgataa
    20341 ctagcgaaat cgtaaagaca gacaaactat cccagggagc cggaatataa aaggctcctt
    20401 cttgtatgaa gcttgccatt cctacatatc ctaaaacaac tagaagaact atagtcccaa
    20461 caacaatgta agtgccaatt ttcattttag gagaatcttg gactaaactt cttcgtaaaa
    20521 ttgtggccac aagtccaaat ccaatcagaa aaataagaag ttgccctaaa aatgtgagca
    20581 aattgactgt taagagagga cctttagaaa aatcacttag tagttgataa taacgtaata
    20641 ccgccaggac aagaattggc gtcaaaaggg actctttgat agaactgcga ggtgctccct
    20701 tgagaatctc tttcattatt tttttaggat tcttacctag ataatcctct gcactcatgc
    20761 catctcgttc tgcttctgag aaatctagca tcatcaaata gatctgctct ctgagatagt
    20821 cttcatcata gagaaatcca gcaagattaa aactttccca caactcctca aaatactttt
    20881 gattctcctc agaaaactca tgtagcaaag cgcttgtttc ttcgtaatac ttcattttct
    20941 tcatggttta acccccattc ttaatccctt ctactttttg actcaaatcg tcccattgtt
    21001 gccaaaagac tgagacacgc tcttctcctt ctttcattaa tgaaaaatac ttccgatctg
    21061 gaccatctgg cgacgggcgc atgtcgcctc ttatccattg atttttttct aacttttgca
    21121 acaaaggata aatagttcct ggaacgatag tatcaaatcc agcctctcgc aaagtctgaa
    21181 ccaactcata accataccgc tctttttgac caatcatatc caagacacaa ccttcaagaa
    21241 caccttttaa tagctgagtt tctttcatca cttctccctt ctaatctatt ttgtaatacc
    21301 tactagtaac ttcacctata gtatatcact tctacactag tttgtaaagc ataatagtta
    21361 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ctaccgtatg tatggttact
    21421 gacttcgtca gtttcatcta caacctcaaa gcagtgcttt gagctgactt cgtcagtttc
    21481 atctacaacc tcaaaacagt gttttgagca acccgcggct agcttcctag tttgctcttt
    21541 gattttcatt gagtataaat aaaaaaacag aactagcctg aactagtcct gtctactttt
    21601 acccaatcac acttccattt ggtacagctg gatcaactgt gagaagggtt aatttgccat
    21661 catgttcagc tgagagaatc ataccctggc tgacatattt tttcatcatt ttacgtggtt
    21721 tgaggttagc aatgatttga actttcttgc cgaccaattc ttgttcattt ggatagtatt
    21781 ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc agcatccaag cggaattgaa
    21841 gcaacttatc tgaaccttct actttagaca cttctttgac ttctgccaca cggatttcaa
    21901 ccttgtcaaa gtcttcaaac ttgatttcat ccttgtttag tttgagctca acttcgtccg
    21961 gattccattc tttttcgact gctggtttat tgccttccat ttgttccttg atataggcga
    22021 tttcttcttc catatttaga cgtggaaaga taggtgttcc tttggcaact acagtcacat
    22081 ctgctgggaa gtcagccaaa ctcaagtttt caagactaga aacttcttcc aaaccaagtt
    22141 gagtcaaaac tgcacgacta gtttccatca taaatggttc aatcaagtga gcaactacac
    22201 gaatgctggc tgccaagtgg ctcatgacac ttgccaattg gtcacgaaga gcttcatcct
    22261 tggccaagat ccatggtgcg gtctcatcga tgtatttatt ggtacgagag atcagagtcc
    22321 agactgcttc aagcgcacgt ggatagtcaa ctgcttccat gtgtgtatgg aagtctgcga
    22381 ttgattgttc tgcaacctca gcaagaacat ggtcaaattc agtcacacct tctacatagg
    22441 cagggatttg tccatcaaag tacttattaa tcatggaaac cgtacggtta aggaggttcc
    22501 caaggtcatt agccaattca tagttgatac ggccgacata gtcttcagga gtaaaggttc
    22561 cgtctgaacc aactggaagg ttacgcatga ggtagtaacg aagtggatct agtccataac
    22621 gctctaccaa catttcaggg taaacgacat tcccttttga cttagacatt tttccgtctt
    22681 tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa tttaacatcc aacatcataa
    22741 gaaggattgg ccagtagata gagtggaagc gaaggatgtc ttttcctacc atatggaaga
    22801 ctgttccatt ccagaacttg tcaaagttac catgttcgtc ttgagcgtag ccaagagctg
    22861 tcgcatagtt aagaagggca tcaatccaaa cgtagacaac gtgttttgga tttgatggga
    22921 caggcactcc ccatgtaaag gttgtacgag ataccgccaa atcttccaaa cctggctcga
    22981 tgaagttgcg tagcatttca ttaagacgac catctggcgt gataaattca ggatgagctt
    23041 tgaaaaattc gaccaaacgg tcttggtatt tgctaaggcg aaggaagtat gattcttcag
    23101 aaacccattc aacctcatga cctgatggag caataccacc agtcacattt ccagcttcat
    23161 cacggaaaac ttctgccagc tggctttctg taaagaattc ttcgtctgat actgaatacc
    23221 aaccagagta ttcacccaag tagatatcat cttgagcaag taagcgttca aagacctgtg
    23281 cgacaacttt ttcatggtag tcatcagttg tacggataaa tttatcgtat gagatatcta
    23341 gtaattgcca gagttcttta actccaaccg ccattctatc aacatagact tgaggtgtaa
    23401 taccagcttc ttccgctttc tgctggattt tctgaccatg ttcatcaaga cctgtcagat
    23461 aaaatacatc gtagcccatc aggcgtttgt aacgtgctag gacatcacat gcgatagttg
    23521 tgtaggcaga accgatatga agtttcccag atggatagta aatcggcgtt gtaatataaa
    23581 aattcttttc agacataatt tttcctttcc aggcaaatga aacctgtttt tctaacactt
    23641 cattatatca catttttaat gaatttcgat agggaaatcc atacaaaaac aagatagacg
    23701 agtgtccatc ttgttgatct tattcataac gaagggcttc aattggatca agtttcgatg
    23761 ccttgttggc tggcaagact ccaaaaatca taccaacact agccgaaact gcaagactaa
    23821 atagggcaac tgggattgat actccaactt ctataccttc tattaaacct tgcagtaaca
    23881 aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc aattaagcca cctaacaagg
    23941 tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt ggcacgtgtt gcacccaaag
    24001 ccttacgaag accaatctca cgagtgcgct ctgtcaccga aaccagcatg atgttcatga
    24061 caccagttcc tccaacaaag agagaaatcc ctgcgatgga actaataatc gtcgtcataa
    24121 aactaaacga ttgttgaatt tctgcaaata caacggactc atctgccacc tggtattctc
    24181 cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag ttctggaccc agagttgggg
    24241 ttaaactggt atcattcact cgaaagacaa tattagctat ttcatctaca ttaaaattcg
    24301 cagcaaggga gatattggta gtaataggca agccaccaaa cccatatatt tttgatcttt
    24361 tagcctccgg actagtataa accccaatga cccggtaact aaatccattg acttctacaa
    24421 ccttgttaat agcctcttga ggagattcaa ataaactaat ggacaattcc tcatctagca
    24481 aaatgacact tgcaaactct ttgaaatctt gctctctcag actacgacct gcaataattt
    24541 cattcttaac agcgtccatg taagttctgt ttccacctgt caaattagca ttctcaacct
    24601 ttttatcttg ataggtcaag atggcattcg ttgaattggt tacatagtaa ctatccactc
    24661 ccttcagttt agctgcctct tgaacccagg attcttgcgg ttttggcggt tcaacaggaa
    24721 cttcctcttc ctttccagaa accgtaaaag ctgattgttt ctgagtaaaa gacccatctt
    24781 tacttttttt aggagagaaa aagacgctaa tatttttctg agatttagtc atatctttat
    24841 tgacttgacg agatagggaa tcacccaaag ccataatcac aacaactgat gaaacaccga
    24901 taataatccc aatcatagta agcaaagaac gcatcttgtg agccatgata gatgaaaagg
    24961 caaatttcag attctgcatc ttagttttcc tcctttccta actgagcact gtcagacgaa
    25021 atgaccccat cccgaatgac aatctgacgt ttggcataga cagcaatctc aggctcatgc
    25081 gttaccatga taatggtttt tccttcttta ttcaaatcaa ccaataattg cataatttgg
    25141 ttacctgttt tggtatccaa ggctcctgtc ggttcatccg ctaggataat agaaggattg
    25201 tttaccaagg cacgcgcaat ggctacacgt tgcttttgac caccagataa ttctgaaggt
    25261 aaatggtgac tacgttctgt caattcaacc ttgtctaaat attcctcagc caacttgcga
    25321 cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt ctacattttg cagagcattg
    25381 agcttcgata gaagaaagaa ctgctgaaag acaaaaccga tttgttggtt acggacctta
    25441 gctagttgtt tttcaccaag cccagccact tcttgacctt caagataata ttctccactg
    25501 gttggtgtat ccaacatgcc aatcgtattc atcagagtgg acttaccaga cccagatggt
    25561 cccatgatgg ctacaaattc accctcattc acttctagat tgatattttt gagaacctgc
    25621 agttcttggt caccattacg gtaacttctg aagatatttt ttagactaat tagttgcttc
    25681 atcagccttc acctcttttc cttcttccaa ggaagatgtt ggattactga tgaccttagc
    25741 accgttcgtt aaaccagaag tgatttcttg attttctgcg tcagcatttc ccaatgaaac
    25801 ctcaactttt ttagcctttt gttgttcatc cacaatccag acataatttt tactatcatc
    25861 cattactaga ctgctaacag gaacaagaat agccttagtt ttgcttttaa cctcaatgtt
    25921 gacagaaaaa ccttgtttca aatcaccaac ctcgcctgtc acatcaatag tataagggta
    25981 tttagaacct gtattattcc cggctgctgg actagctgct tcaccattgt ttttaggata
    26041 gtcagaaata tagcttaatt tcccagtcca ttttttatca ggatacactt tagaagtaaa
    26101 gcttacttct tgacctacag aaaggttggc tagattgtac tcagacaatt ctcccttgac
    26161 ttgtaaattt tcattgctga caatatgaac cataacttga ctcgcccctg ttggagattt
    26221 agaaacattg ctattgactt cgactacagt tccctctagg gtactgagaa cagttgttgc
    26281 atccaattga ctttgagcct tgcttaattg cgctgcagca tctgcacgcg catcacgggc
    26341 atcacccaat tgagcatcaa tagaagcaac agaatttcca gccactggag ttgggctttg
    26401 caccgttgca tcttctcctc ctactggcgc tggtaactgt ggaacctgag ctgaagcggc
    26461 ttcatttcgt gcttgattga gttcattgat atgacgatct gccttagcta ctgctcgact
    26521 agctgaatca taggccgcct gcgcttctga actactgtac ttgactaaag cctgcccttc
    26581 gctgacctta tcgcccacag aaacaaggat ttcatctaaa tcacccttac tagcatcaaa
    26641 ataaacatat tgttcatttt ttgctgttac tgtccctgac aataaaacag aggatgccac
    26701 gcttccttcc ttggcaacaa caagatgagt aggctcatct tttacagcag tctgagaagg
    26761 ttgtctaaaa agtaaaatcc ccccggcacc caatacaact acactcgcag caccgattgc
    26821 tgcatacagt tgccactttt tagctttacc attctttttc ttcataatga aactcctttt
    26881 cttttttaca atactttgct attataccaa atttccctcc agcaaacaat gcagttcaga
    26941 tggaaataat ggcagttcag gattaaacaa tcgttcggaa ttttgctttt ctattgtact
    27001 agatatataa tacactatct tgacttattt ggcaagcttt tttgcaattt tttgtgcgta
    27061 gcagattttt gcaatcaaat caaaaaaaga ataaaatata actatcaaaa aagacgctct
    27121 actatttaaa agattacaaa ggagttttca atgagagaat atgatatcat tgctatcggt
    27181 ggaggtagcg gaggaatcgc taccatgaac cgtgctggtg aacatggagc caaagcagcc
    27241 gttattgagg aaaagaaatt aggtggaacc tgtgtcaacg tcggttgtgt tcctaaaaaa
    27301 atcatgtggt acggggcgca aatcgctgag actttccatc aatttggaga agactacggc
    27361 tttaagacta ctgatcttaa ctttgacttt gcaaccctac gtcgcaatcg tgaagcctac
    27421 attgatcgcg ctcgttcttc ttatgatggt agttttaaac gcaacggtgt agacttgatt
    27481 gaaggtcatg ctgaatttgt agattctcat actgtaagcg taaatggtga actgattcgt
    27541 gctaaacata tcgtgattgc tacaggtgcc catccaagta ttcctaatat tcctggtgct
    27601 gagctaggtg gctcttctga tgatgtattt gcctgggaag aacttccaga gtcagttgcc
    27661 attctaggcg ctggttatat cgccgttgaa ttagctggcg tactccacac ttttggtgtc
    27721 aagacagatc tctttgttcg ccgcgatcgt cctttacgtg gttttgattc ctacatcgtt
    27781 gaaggtttgg tcaaggaaat ggaaagaata aacttgccac ttcatactca caaagtccct
    27841 gccaagttag aaaaaactgc taaaggcatt accattcatt tcgaggatgg taccagtcac
    27901 acagctagcc aagttatctg ggctacaggt cgccgtccaa acgttaaggg cttgcaactt
    27961 gaaaaagctg gagtgactct gaacgaacgt ggctttatcc aagtagatga ataccaaaat
    28021 actgttgttg agggaatcta tgctctaggt gatgtaacag gtgaaaaaga actgactcca
    28081 gttgcaatca aggctgggcg taccctatct gaacgtctct ttaacggaaa aacaactgca
    28141 aaaatggatt actcaactat tccaactgtt gtcttttcac accctgctat cggaactgtt
    28201 ggtttgacag aagagcaagc tattaaagaa tacggtcaag accaaatcaa ggtttacaaa
    28261 tcaagctttg catctatgta ctctgcttgc actcgcaacc gtcaagaatc ccgtttcaaa
    28321 ctcataacag ctggttcaga agaaaaagtt gtcggacttc atggaattgg ctacggcgtt
    28381 gatgaaatga ttcagggatt tgccgttgct atcaaaatgg gagcaaccaa ggctgacttt
    28441 gatgcaactg tggcaattca cccaactgca tctgaagaat ttgtaaccat gcgttaatcg
    28501 aaacaaaaga agctgatata aatatgtctg cttctttttt aatgattttc gaatcaacaa
    28561 aaaaattatc caacttgact agtcacgaaa atcggctgtt acagtttttg ttaccttgtt
    28621 tttaaaaaat ggttgacatc gactcctata tgagtataat agttagtata cattagaaaa
    28681 gaggttaact attttgaaaa aagctcacgt ttatgctatc cctgctattg gggctgctct
    28741 cattgctgtt ttggcacaaa tcagtcttcc aattggacct gttcccttca ctctgcaaaa
    28801 ctttgcaatc ggcttgattg ctactgtctt tagaccgaga gaggctgtac tttctgctgg
    28861 actctatctt cttctaggtg ctatcggtct tcctgtcttt gcaggaggtg gagctggttt
    28921 tcaggcttta gttggcccta ctgcaggcta tctttggttt tatctcgttt actctggact
    28981 tacttcctct ctaaccaaca gcaagagtgg tgttgttaag atttttcttg caaacctctt
    29041 gggtgatgcc cttgtctttg tcggcgggat tctcagcttg catttcctag ctggaatggc
    29101 atttgaaaaa gctcttgttg tgggggttct tccctttatc attccagacc ttggcaaact
    29161 tctggctatt agttttatta gccgtcccct acttcaacgc cttaaaaatc aggcttactt
    29221 tactaactaa aaaaggatac cgagttatca tgactcaata tccttttttt attttgaaaa
    29281 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gctcaaaaca
    29341 ctgttttgag gttgtggatg aaactgacga agtcagtaac catacatacg gcaaggcaaa
    29401 gctgatgcgg tttgaagaga ttttcgaaga gtattagttg cctttaaagg catccaccat
    29461 cgtttgaaat tcttcatttg agagagtaat ccctttgccc attttagtat ggtctggact
    29521 ccaagcacga atatcaaact ttgcaggggc accattaaag ctcacacggt taatttcctt
    29581 ggtccaacct ttttcgtttt cagaaagagt caacaagtgc tcttcgattt caaatgtaaa
    29641 ttctgccatt ttcttctcct tttttagttt cattagttta ttcgtaaaat cttgtagatt
    29701 ttaggaaaat tttatataat attgatataa aagaagggag gccaatatga gacataaatt
    29761 ccagcaagtt ctaaataaaa tacatgattt tttaaatgga tatgaccaac ctgaccagac
    29821 tgaaaccaac tcccttacag ccactattga agaggctatc cagaaacaaa ccgctgttca
    29881 ccttatctta tctgagacaa gctttacagg tgacatcatc aaatatgatc agcaaggcca
    29941 gcaaattatc gtgaaaaatt tttccaaaaa tgtgagccgg attatccgta taagcgatat
    30001 tcaacgcctg cgatttgtcc cctcaactgt ccaaacagcc caaaaaaata gatttaagaa
    30061 agagtgagat gtagttgctt catcccactc tttttcttag cgaatttgtt caaaatgtaa
    30121 atgaactgcg atatgatctc cataaccact tctttccaag tcacgttgta aacgatagga
    30181 aatatagtgt tctgcaatgg taatgtaacc tgcgcccaat aaacgatgtt caaccataga
    30241 ttgaatcata ctgatagtcg cacgttccac cttggcttct tgtaaatcca aaactacctt
    30301 cttagtgact tgagcaagat tttgacgcaa atcatctgtc aaaacataaa cagtttgggc
    30361 tgccttcaag atggcttggt aaatcttatc tggattaaat tcagcaattt cgccattacg
    30421 tttgattact tgcataggtt tctcctttat tctttgtttt ctttgatttc tgccagcatt
    30481 ttttcttctt ctactgtcag ttgataatgt tcaagtaaat ccggtctgcg ctcgtaggtt
    30541 ttctttaaac tctcgtacaa tcgccactga cgaatctttt catggtggcc actcatcaat
    30601 acatctggca cgaccatgcc tcgataatca tagggacgtg tgtactgagg atattctaaa
    30661 agacctgaag aaaaactatc atcttggtgg ctagactcct tgccaatcac ttctggaatc
    30721 aggcgaactg tagcatcaat catggtcata gctgccaatt ctccaccagt gaggacatag
    30781 tcgcctaggg aaatctcatc tgttaccaag gtcttaatgc gctcatcata accctcatag
    30841 tgcccacaga taaagattag ctcttcctct tgagccaaat cttcagcata agcctgatca
    30901 aactgctttc cagcaggatc gaggagaata acgcgcggat ttttcttttc aatagcatca
    30961 aaggaatcga aaataggttg tactctgagc aacatgccct gaccgcctcc gtagggctca
    31021 tcatctacat gacgggcctt ttcagcattt tctcgaaaat tatgatactg gatatccaag
    31081 agcccttttt ctcgagcctt tccaacgatt gagtgctcca gtggagaaaa catctctgga
    31141 aagagggtta aaatatcaat cttcatcgtc taacccttct aagatttcca catcgacccg
    31201 tttatttgga atatcaacat tgagaaccac tggtgggata taaggtaaaa gcaaatcacg
    31261 tttgcctttt cgtttgacca cccagacatc attagcacct ggttgcagga tttccttgat
    31321 ggttccaacc aagctatcac cctcatagac ttccaaaccg ataatctcgt gatagtaaaa
    31381 ttcaccatcg tctaggtcat tcaaatcttc ctcagcgacc ttgagactgt atcccttgta
    31441 cttttcgata gtattgatat ggtacatatc tttgaattta ataatgtcaa agttcttctg
    31501 tttacggtgg ctagcgatgg tcactgtttg gacaaactga tctttttcat caaacaaagc
    31561 cagctcagct ccttttttaa accgttcttc tgcaaaatcc gtcacagaca agactcgcat
    31621 ctcaccctgt aatccctgcg tattaacgat tttcccaaca ttaaagtagt tcatcttgtc
    31681 tcctgtaatc tccttttttc catcttattc tgacaattct cgaataatag ccgcaatttt
    31741 ttccgattct gaccattgta aataatggtg attccctcct aaaatgagtt tagtattgga
    31801 agtccaatat tctgattctc tgtactcttt ttctctataa ggctgacaaa aaacaaatac
    31861 aggaatatga gcttctatag atacatcctc aaaatcttcc tcagtaatct ctccagatat
    31921 ctgaaattct ggatcttgat tttccaactc taagcctttt tcttgcatta attcccagat
    31981 ttttttattc gtttcaggac taaatgttgc ttgagttaaa ttcttcaaat aaagttcagg
    32041 tccatactcg tcaatcagcc tcatctgctc ttccatttct ggataaggat tttctgaaaa
    32101 atcagcaaac atgacttttt tagttgtcgg ttcaattgct actaaagtct gacacttaat
    32161 tggtttctcg agtaatttgc aagctaaaat tccactccaa ctatgtgcac aaagtatata
    32221 ttcagaaatc cctaattctt caagtacttc ataaaccaca tctgcaagat tatctagatt
    32281 ttttccagct tggtcatgaa tcggactcct acctgtgttc ggaaaatcaa ttgtcaaata
    32341 accaattgta ggaggaggtt tttcaagtat aagtgaaaaa ttttcataac ttggtagcaa
    32401 acctgctccg tttagacaaa ctagcacttt cttttgcttt tgataagtaa cagagaggct
    32461 accaatttct gtagatactt caaacctctt cataaagaaa tccactcatt ctatataatg
    32521 aattattaaa aatccttatc ctttatttta tcacgttcca aggattttct caagttggag
    32581 gaaggggaca acatctctac tttcccttca agaatccttc caaatcatgt ttatgttggt
    32641 aattaacggc tgcggttttg tctttctcaa agacagtctt ggtaaggtca atatgcttga
    32701 tagcagcaat agcgacggtg tagtaaatga tatcagccag ttctctggca agttcctcgt
    32761 tcgaatccta tcccttcttt tcgaccagag cgcctattca aaacctcggc tacttctccg
    32821 acttcctcca ctaacttcat aaagagacct tcatcagtcc gagactgctg ttaatgttcg
    32881 agtaagtagt cttggaattg cctaaacgtt caatctttta tagtatattg aaactagaat
    32941 agtacacctt tacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt
    33001 cctgttatta tttcatttta ctatatcttc tattccacac aaaaaagcga gacatccgtc
    33061 ccgcccttct tatttttcgt caataacgat tcttactttt ttgtattcag ttgggacaga
    33121 gtagacaatc gttcttatcg cagaaatagt gcgaccctta cgaccgatta cacgacccac
    33181 atcgctttga tcaagattca aatgatattc caaaaattct ggtgtatctt caatcttgat
    33241 agttaaggca tctggttgtg aaattaaggg tttcacaatc gcaataatga gattttcaat
    33301 cgtatccatc tgtcaaccta ctttaaactt attttgagaa tttagaatcg tggaattttt
    33361 tcaatacgcc ttcttttgaa aggatgttac gtactgtgtc tgaaggttga gctccattag
    33421 ccaaccatgc aagaacgcgg tcttctttca aagttacttg gttttcagca acaagtgggt
    33481 tgtaagttcc aactgtttcg atgaaacgtc cgtcacgtgg tgaacgtgaa tctgctacgt
    33541 tgatacggta gaaaggtttt ttcttagaac ccatacgagt caaacggatt ttaactgcca
    33601 tttttaaagt ctcatttctt taatttttta tttcggtgaa atagctgagc tatttagcac
    33661 atgagctatt tagcacatgt tctattatag cagatttctg gcatgtgtca agaaaaaaac
    33721 ttgacagact ataaatttct taaagtattt agaaatttgt tagaatagga aataaatgtt
    33781 tgaaagatac tatccgtgaa tactatttta gaaaaatttt ataaagaaca ccaagtcaaa
    33841 cccttcatat cgcctgaacg agatttggat acttggctcc taagtcccaa gcccgttccc
    33901 aagcgaaata tgaacttatt agcagatgat tcactagcag gagatatcat tttactatgg
    33961 agaatccagt ttggtacttt taccactgaa acatgatttt aaaaactccc attcgaatat
    34021 gattcaaaat tcgcttagaa tcaatgtttt cccacttttt caaaaaataa attttcatct
    34081 aatttaaata actttcaatt aagtgtgaat tttgcttaaa atcattaaaa aacaccccat
    34141 ggtgtgaacc atgaagtgtt gtaaatgctg tgttgtagct agttcttagc gtttagagaa
    34201 ctggctagct ttacgagctt tcttaagatc tggtttccaa aatactttga gtacacttat
    34261 ggtattgatg cccctaaaca tctaaaaact ctggtagaaa aagggtatgc tcttgtcgaa
    34321 acttcttttg actcacttga ccatctaaat actaccatga aaaagaatat cctgaagaag
    34381 aagggagtta ctggactttc taaaatgaaa tcttgcgacc tggatcaagc ccttcatgag
    34441 catttttcag aagaagaatt agctggtcac tttcatgtcc ttctatggac ttttttacaa
    34501 tggcattgct atcacaccca atacctatct aagcgcctgg ttcgtaaact ttattgcagc
    34561 tcttcctcta aatttcctaa ttgttgaacc aattgcccgt tttatactaa gttcttttca
    34621 gaaaccattt actggggaag aagttgaaga ttttcaagat gatgatgaaa tcccaactat
    34681 tatctaagcc agttctgtaa actactaata tttgaaatcc acttcctttt agggtacaat
    34741 ggttataaat gaatttttga gaggatcaga atgaaaaaac tagcaaccct tcttttactg
    34801 tctactgtag ccctagctgg gtgtagcagc gtccaacgca gtctgcgtgg tgatgattat
    34861 gttgattcca gtcttgctgc tgaagaaagt tccaaagtag ctgcccaatc tgccaaggag
    34921 ttaaacgatg ctttaacaaa cgaaaacgcc aatttcccac aactatctaa ggaagttgct
    34981 gaagatgaag ccgaagtgat tctccacaca agccaaggtg atattcgcat taaactcttc
    35041 cctaaactcg ctcctctagc ggttgaaaat ttcctcactc atgccaaaga aggctactat
    35101 aacggtatta ccttccaccg tgtcatcgat ggctttatgg tccaaactgg agatccaaaa
    35161 ggggacggta caggtggtca gtccatctgg catgacaagg ataagactaa agacaaagga
    35221 actggtttca agaacgagat tactccttat ttgtataaca tccgcggtgc tcttgctatg
    35281 gctaatactg gtcaaccaaa caccaatggc agccagttct tcatcaacca aaactctaca
    35341 gatacctctt ctaaactccc tacaagcaag tatccacaga aaattatcga agcctacaaa
    35401 aaaggtggaa accctagtct agatggcaaa cacccagtct ttggtcaagt gattggcggt
    35461 atggatgttg tggataagat tgctaaagcc gaaaaagatg aaaaagacaa gccaactact
    35521 gctatcacaa tcgacagcat cgaagtggtg aaagactacg attttaaatc ttaaaaacca
    35581 aaaaaataca gtatccacat tcggtactgt atttttttta ctctcattct taagttaaat
    35641 tattaaaatc ccatatttgg tctatccagc cttcataaaa gtctggctcg tggcagacca
    35701 taaggataga tcccctgtat tctttgagag cgcgtttgag ctcatccttt gcatccacat
    35761 ccaaatggtt ggtcggctcg tccagcacta aaacgttgtt ttcacgattc atcaagagac
    35821 agaaacgaac cttggcttgc tctccccctg ataatacttg aatctggctt tcaatatgtt
    35881 tggttgtcaa accacaacgg gcaagggctg cacggacttc tgcttgatta agggcaggaa
    35941 aggcattcca gacagcttca agaggagttt ggcgattacc gccttctact tcctgctcaa
    36001 aataaccaag ttctaaataa tctccacgct ccacttcccc agcgattggc gagataatgc
    36061 ccaagagaat cttcaagaga gttgtttttc caataccatt agcaccaata atcgcaacct
    36121 tttgattgcg ttcgaaggta agatttaaag gcttagtaag aggacggtcg taaccaattt
    36181 gcaagttctt ggcttggaag ataaagcgcc ctggtgtacg agctggtttg aaatcaaagg
    36241 atggttttgg tttctcactt tggagttcga taatatccat cttatccaat ttcttttgac
    36301 gagacatagc catattacga gttgcaacac gggctttatt acgagccaca aagtccttga
    36361 ggtctgcaat ctctttctgc tggcgttcgt aggctgcctc tagctgagat ttcttcatag
    36421 cataaacttc ttggaactgg tagtagtcac cagagtaacg cgtcagctgt tgattttcca
    36481 catgatagac aatattaata acgtcattga ggaatggaat atcgtgcgaa atgagaacaa
    36541 aggcattctc atagttttgg agatagcgct tgagccaatc aatatgctca gcatccaagt
    36601 agttggtcgg ctcgtccaac agcaagatat caggcttttc aaggagaagt tttgccaaaa
    36661 gcaccttggt tctttgccca cctgacaaag aagttacatc cgtatccatg ccaaagtcca
    36721 taacaccaag agcacgcgct acttcgtcaa tcttagcatc caaggtatag aaatcacgac
    36781 tctccagacg gtcttgaagt tctcctactt cttccatgag agcatcaaca tccgcgccgt
    36841 cttcagccat tttcatatag aggtcattga tacgagcttc agctttgaaa agctcatcaa
    36901 aagccgtacg gagaacatca cgcaccgact gtctttcagc aaggacagag tgctgatcca
    36961 agtaaccagc cgtcacatat ttggaccact caacctttcc ttcatctggc agcattttac
    37021 cagtcacgat actcataaag gttgattttc cttcaccatt ggcaccgacc aggccgatat
    37081 gttctccctt gaggagacgg aaggacacat cttcaaaaat tgcacggtca ccaaaaccgt
    37141 gactcagatt tttaacttct aaaatactca ttttaattcc ttatcttgtt tttatgtaat
    37201 cgtttataaa ggagccaagc cagatagcca cccaaagtgt tggtccacaa atcatcaatc
    37261 tcaaagacgc gattgaaatc aaagaaaaag tctaagatta attgcgtaca ctcgattcca
    37321 agactcacaa gaaaactaaa aagaaggacc ttttttgttt tccgcaaatt tggaaataga
    37381 taaaggagtt ggaaaatcag aggaaaaaac aagaagacat tgaggatatt ttgtaaaaaa
    37441 atccaacata attgtccaat gtcactcact tcgcccagtt tccagagaga attgaaagga
    37501 gtcaaaagaa aaaccaggcg tccaagatgc tgaatacctg gagttcccac tcccacggta
    37561 gattgttctt gaggagtaaa gcaaaaacag acaatgcaaa tgctatagaa aatgactccc
    37621 cagaccaaaa tatgattata agtcttcttc atcattaagg atttaccgct gcgactgcct
    37681 tctggcggtc acgtttcatt gtgttaaagc gcaattgtcc acaagctgcg tcaatatctg
    37741 taccatgctc ttgacgaacc acacagttgc cccctttttt cttaagcgta tcatagaaag
    37801 ccaacacgcg ctctttggga ctacggctat attggtcatg ctcactaact gggttataag
    37861 gaatcaagtt tacataagac aatttcttga tgttcttgag caattcagcc aattccaagg
    37921 cttgttctac accgtcattg acttcattaa gcatgatata ttcaaaggtt acacgacggt
    37981 ttgttgtctc aatgtagtat tcaatagcag caaagagttt ttcaatcgga aaggcacggt
    38041 taatcttcat gatacttgaa cgaagttcat tgttgagtgc gtgaagagac acggcaagat
    38101 tgatctgaac cccttcatca gcaaagtcac gaattttatg agccaaacct gaggttgaaa
    38161 ccgtgatgtg acgagcaccg atagccattc ctttatcatc attgatagta cgaaagaaat
    38221 tcaagacatt gttgtaatta tcaaagggct caccgattcc catgacaacg atatggttga
    38281 cgcgttcatc ctgaccacgc tcatcaaagt atttctgaac cagcatgatt tgcgctacga
    38341 tttcaccgtt attgaggtca cgctgcttct taatcaaacc agaggcacag aaggtacaac
    38401 cgatattaca gccgacctga gtggtcacac agacagataa accatagtgt tgacacatga
    38461 gtacagtctc aattaacata ccgtcaggca attcaaagag atatttgact gtaccatcag
    38521 cagactcttg cacaatacgt tgtttcaagg gattgaccac aaactggtca ttgagcttag
    38581 caatcaaatc cttggaaagg ttggtcattt cttcaaatga ctgcacacgt ttacggtaga
    38641 gccattccca gatttgatct gcacggaatt tcttttctcc ctgctccaat acccattcct
    38701 gcatggtttg atgtgccaaa ctatgaattg agggtttcat ttcttctcct tattctctac
    38761 tcacttctga cgaatgacaa aatgacgttg ttccttgtcc tctttctgag aatgctggtc
    38821 tttctgacga cgtctatttt tcttatctgc attcgacttt cgtttagttt gagtcggttt
    38881 ctttcctttt ctagaaggtg tttcttcttc cgtcttacgc attttcttgt caaatgatgc
    38941 tcgcttaggg gcttcatttt ctaagacaaa ataggcacaa ccataactac aatactctaa
    39001 aaggtagtct tgtaaacgac tgattttttc aagtttttct tctgttcggt catccttgta
    39061 aaaacctcgt aggcgaagct gttcgttgct ccagtccccc acgatataat caaacttggt
    39121 taatacttct gaaaaacgct gattaaaagt cgtcacatca aaggcatcct tgatattttc
    39181 aaccaaggca aaagctatcc cttccgtttc gaccttgtcc ccgtgtaaat ggaactccgg
    39241 accaggaaac ttgttatagt tgtataattc aggtgcaatt tcttttcgca tagatatcct
    39301 ttttccacga ttacttaata ctttattcta ccataatttc tagcagttag cacgtttctc
    39361 ataaaaatga aaaaagtctg acgattttgt cagaccagaa tcttataacc taaaaaagag
    39421 aagaacaatt cttccctcca actatcatta tttagcagct gcgtacaatt catctacttt
    39481 attccagttg attactgaaa agaaagcttt gatgtagtca ggacgcacgt tgcggtattt
    39541 cacgtagtaa gcatgttccc aaacgtccaa gcccaagatt ggttttttac cttctgagat
    39601 tggtgtgtct tggtttgctg ttgaagtcac ttcaagtttc ccttctttgt tgacaaccaa
    39661 ccatgcccaa cctgaaccaa aacgagttgt tgctgctgca gtgaaggctg cttggaattc
    39721 ttcaaatgaa ccaaatgttg catctattgc tgctgccagt tctgctgaag gagctgtttt
    39781 ctcgggagtc atcaattccc agaaaagagc gtggttcaag tgtccgccac cattgttgat
    39841 aagtgcttga cggatatcag ctgggataga ttctacatca gcaagcaagg cttcaaggtc
    39901 ttcaccgatt tcagggtgtt tttctaaagc tgcattggca ttgttgacat aagtttgatg
    39961 gtgtttgtca tggtgcaaat gcattgtttc cgcatcgatg tatggttcca aagcgtcgta
    40021 tgcatatgga agttctggta agataatagc catctgtaat acctcttttt ctttctatat
    40081 gaaaatgata acgcaaacat tcactttttt caagtttttt gcttatagat aaggaaatca
    40141 ctgacatact ttctaataaa ataagcaaat cagcaagaaa cccacgacaa gataatcctg
    40201 acgcgagttg tagtttcaac aaatgtcaat tgacctgact agcaatctgt aagagtgcct
    40261 tttcaaaaag gaaacctttt tcataaagac ctgtcttaat ctgatagtct gtctcaatca
    40321 aataggaaat agcttgcttc agaaagctca aagaaagtcc tctcgaatct cttaatgcaa
    40381 acttgatttg ataaggattt gggttacgtc ccagataact acctaaacta cttgcaatct
    40441 gcgattctgt ttggccagac tccgccaaaa tcttcacctg agtaaaagtc cgaaattgtc
    40501 ccagcatgac tgcaatcagt ttgatttcat cttccccttg caaggtcaag tctctcacca
    40561 aatcgcgcgc ctgatccatc tttttagtca gaataaactg agttaaatca aaaatattgt
    40621 cctgcaaggt cttgggaatt gcgttaacaa tatcctcttc ctcaataaca gaattcgcct
    40681 tataggactg taaaaagaga agatttttct ggatttcgct aaattgaaac cccgacttga
    40741 tgaggagatt ttcaaaagaa tgattggtaa actgcagacc ttgtttctga ctccactttt
    40801 ggaaatactg gcgcaattct tgttctttta cttctactgc atcgaagacc ttggcatcac
    40861 gcttaagtaa tttgactaac cgtcttttgc tatccagctt tccttctgca aagattatca
    40921 acttggttgt tggagaagga ttgtcaaggt attcctcaaa tgacttaagc tcatcatctg
    40981 tcaaaaagcg tttcttagca gtcgtgatat ccataaaata atctaatatc acgattttct
    41041 catccgcaaa gaaaggaagg ctgaccaact ccagttccac atccttgtaa actacttctt
    41101 tcatatcaaa gtaggcaaag ttgaggtcag cagaatcata cccaatctgt ttcaacattt
    41161 gactcttcat cacttcaaac tgaccctgat ctgtccctgt aaataggctc aggctcggta
    41221 aatttgataa agtcaacttc tgactttctt caatggctag catcgtctct cctttcttca
    41281 gattttttga tttaatttag tcaatatagc gcaatttccc acggaaatct tctaagctct
    41341 cgtagccttt ttccaccatg attgctttca gttcattggt aatgcagtca aaagcactga
    41401 cgccttcttt gtgaagggtc gttcccacct gcaccatact tgctccacag aggatgtgtt
    41461 caaaggcatc tcgaccagtc agaacgccac ctgttccgat aatttggatt tgaggattta
    41521 aacgttgata aaaggcgtga acattggcta gagcagtcgg tttgatgtat tctccaccaa
    41581 ttccaccaaa accattctta ggccgaataa cgacagattc gtcttctata tagaggccgt
    41641 ttccgataga gttaacgcag ttgacaaact tgagcggata tttgttgaaa atagctgccg
    41701 cttgatcaaa gtgaacaata tcaaaataag gtggcaattt aattccaaga ggtttggtga
    41761 agtaagcaaa cacttctgcc aaaatccggt ctgttgtctc aaaatcatag gcaatctgag
    41821 gtttacctgg aacatttgga caggaaagat ttagctcagt cagaccacga aaatcactct
    41881 cttggacttt tttcaaaata gtatgggttt cctctggaga catgccgacc agagataaga
    41941 agaaagttcg gttcgactct ttttcctgca aatctaaaag ataatccaaa taatagtcta
    42001 agccattatt tggcaagccc atagagttga tggaaccaag tggaacatct tggtagcgtg
    42061 gctcaggatt cccctgacgt aagtccaagg tcgctgtctt agtaacaaag gttcctgccg
    42121 ctgagttttt gacctcttct aactcctcta tcgtcataca agccacacct gctgcattca
    42181 tcaagcaatt gtcaaactca aaaccagcaa tttgtgtttt cgttgatacc atgattctaa
    42241 tcctccagat ttcttttatt gctaatatta taccataatt ttaattctag gtttactaga
    42301 ttctgtggtt ctatctattt attcggaaaa gaaagtctag tacagaagtc atgctatgga
    42361 aacagctagt gtattggaag tttgaacaag gcttgggtaa cagacttttg aatgaagtcc
    42421 aagcaacaag gagaaatctc aaccatgagt ccattccatg actctgttgc tctagaaaac
    42481 cttgcaatag tcaagtgata acgaataaaa ctttggcttg aaatatcccc atgattatct
    42541 attacgagga gaaatctcaa cctttatcat ttttaaagaa atattgtaaa atgaaacaag
    42601 aacaggagaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagttgagg
    42661 tgtactattc tagtttcaat ctactataca tgtaaatctc tactttcgca aaatggattt
    42721 tcagaacagt atcccagtat agttaaaaac tataaaaaag agaggacgtt cccctcttaa
    42781 aatcttattt tactgcttct ttcaaagcat ctaccttatc caaacgttcc catggaagat
    42841 caatatctgt acgtcccatg tgaccgtaag ccgatgtttg acggtaaatt ggacgcttaa
    42901 ggtccagcat ttggataatc cctgcagggc gaaggtcaaa gatttgacga gccgcttttt
    42961 caagttgact ttcagctact gttcctgtac cgaaagtatc gatacgaaca gaaacaggtt
    43021 gcgcaacacc gatagcatag gccaactgca cttctgcctt cttagcaagg tctgctgcaa
    43081 cgatattctt ggcaatatag cgagccgcat aagaggctga acgatccacc ttagtcgcat
    43141 ctttaccaga gaaggcacca ccaccatgac gagagtagcc accataagta tctacaataa
    43201 tcttacgacc agtcaaacct gagtcccctt gaggaccacc gattacaaaa caacctgtcg
    43261 gattgataaa gaattttgtc ttatcatcaa gataagaaga tggaataact tctttgatga
    43321 ccttgtcaat cacatcttga tggatttgtt cattagtggc ctctggatca tgctgagtag
    43381 aaataacgac tgtatctaca cgtaccggac ggtcattttc atcgtactca actgtaactt
    43441 gtgattttgc atctggacgg agatagctaa tttctccaga cttacgaagt tctgccagac
    43501 gacgaaccaa tttatgactg agtgcaattg gcaatggcat gagctcttct gtttcatcta
    43561 ctgcaaatcc aaacatgagc ccttggtcac ctgctccaat caagtccagt ggatcttgat
    43621 cagcatttcc acgaacctcc aaggcttcgt taacaccttg agcgatgtca ggagattgtt
    43681 ccaccaaaga tgggtgtact cccaccgtct cagcagaaaa tccatattct gtattggtat
    43741 aaccaatctc tgcaatggta tcacgaacca cacggttaat atccacatag gcatttgtag
    43801 aaatttcacc aaaaacgtgg acagaaccag tatatacagc tgtttcagca gcaacgtgcg
    43861 cctctggatc ctttgctaaa atagcatcca aaatcgcatc tgaaatttgg tctgcaatct
    43921 tatccggatg cccctcagat acagattcag acgtgaataa tttacgctct gacataaaaa
    43981 tgtcccccct taaaaaatat tgttatagag ttacaaagta ctgataggaa aactcttcgt
    44041 aataaatacc taccatctta tcgggactat ataactttat cattatacca tttttaatcg
    44101 caatttgcag tctttaatgt agtgtttcgg tttagatagt tcgttctcat aaagcaaaaa
    44161 gttggagctc aatactccaa caatttctat taaaatgttt ggcgtttagc tttacgctct
    44221 gcacgaccgc gagcgcgatt ttcagcacgc ttggttttac ggcgcttttc atcaaccgcc
    44281 cattgaattt tcttcttata acccggtttg acttttttct ttttcttttt aaccaaacca
    44341 atcatttcga tatcaagttt atcttgtttt ttctcacggt tggcacgacg atcacggtca
    44401 taggtatctt gaaattcccc gtctttgacc atcttaggac taaacttgat tcccaatttc
    44461 tccaactcac ggatatccga gtcatcactt ggctgataaa gggtaatagc tgtacctggt
    44521 aggccatttc gtccagtacg accaacacga tgaacaaaaa aagataagtc ttgcggaatg
    44581 gcatcattga tgacatggct gacaccttca atgtcaatcc cacgcgctgc taaatctgtt
    44641 gcgacaatat actcaaaatc cagattttgc acctgattca tgattcgctt gcgttcacga
    44701 ggggcaatat ctccatggat ttttgcaacc ttcaagcctt gagcagtcag atatgaatgc
    44761 aattcatcag cacgcgtttt agtgttaaca aaaatcattg ccaaatacgg ctgcatcaac
    44821 tgagtcaact ggtaaatttg agcattctta tcatgtccct tggtcgaaat caaccaatta
    44881 tcaatggtgt cagaaataac cgttttggtc ttaattttct ccataacagg attggataag
    44941 tattttttca agaatggttg cagtttttgt gggatagtcg ctgagaagac catgaattgc
    45001 aagtcttttg gaagactgcc agcaatctta tcaacagttt ccaagaatcc catatccaag
    45061 gtcatatctg cttcatcaac aacaaatgtc ttggctttat gaatagctaa atcaccagat
    45121 ttaaccaagt cgtagatacg gcctggtgtt ccaataacaa tatgaggctg attgcttgcc
    45181 aatttctcaa tctggcgagc cttatccgta ccacccacat aattaaccac acgaacttcg
    45241 acatctgagt gagctgaaat ctgacgcgct acttggtaaa tttgagtagc caactcacga
    45301 ctcggtgcag taatcactgc ttgtacacta tcgctagctt catctaattg ctggaaaatc
    45361 ggtaacaaga aagtatgagt cttacctgaa cctgtttttg attctcctac taggtcacga
    45421 cctgccaaaa caataggaat caacttgtct tgcacctctg ttggagttgt aaattttaac
    45481 tccttcaagg cttctctaat atagttttta aattgaaatt tcgtaaatga cataacatcc
    45541 tcgattctat ctatcttatc aattatacca tattttgaac attttcagta gtccgactca
    45601 tctgacctat cacaaggctc tcaatttctc taaatatagt aaaatgaaat aagaatagga
    45661 tgaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagcag aggtgtacta
    45721 ttctagtttc aatctactat acctctctta tactaaaaat catacatttg ctttctttcc
    45781 aaaatgcaaa aagagaagac caaattggtc ttctctcagc cttaaagctt gcgactcaga
    45841 tagatttgtc aaacagtcaa acagttgctt aagaatcttg taaaagtcga aagcttctag
    45901 aaaaattagt acttaatcat ctttccgctt gcgaccaaga agcaacactg ctagacctgc
    45961 aagaagagag ctagtcacta gtccagtgag tgaaagtggt gcagtactac ccgcatttgg
    46021 caatgtagct tgtttttcct tttctcctgc tggaccttga gctggtggat tctcttcagg
    46081 ttttcttggt tgttctgatt gatgtctatc tgcctgatta ttatcagttc cctgctctcc
    46141 ccctggattc actggtggaa ctggatttgg ttgaggtgct ggttgtggcg ttggtgccgg
    46201 ctgtggttgt ggactaggat cttgcttagc ttcaaagacc cacttaccga cgaaggttag
    46261 atttgacccc tcttccactt cttggtaacc taagaatgtc catgtaccat ttgcaacagc
    46321 aacttctaca ggcatcggtg cttctggaac gaaagcaatc gctacagaag aacttgtagt
    46381 atatgttcca ctttgtggga gtaagctcaa tacttctgct ggcaagttgt tgtctgcggt
    46441 tgcactttcg aagcggtaag tcaccttata ggtttgagtt tctggtgcag gcaaaacatt
    46501 aactgataca gacacctcag tagaagaacc atctggatag tcaactcgca ccttacctgt
    46561 gtaagtacct ggttttgttg tgtcaatttg acctgcaggt gtaatatcaa ctaccttagt
    46621 gccagctgga aggtttggca agttcgtcac attatcggtc aagtcaggtg tttgtccaac
    46681 cttgatagtt tcttccgtta cctgaggcgt ataagtttcc gcatttgtcg gattcgcctt
    46741 gaattcccac ttacctacaa actctacatt agccttgtta acaacggcgc tagctgcgtc
    46801 ataacccttg aaggtccatg tgccatcgtt cacactatct atgtaggtct ttgttgtcgg
    46861 ctcttctgca aaaactctcg tcctattgaa gtaagttgag ccatcttttg gtgctttctt
    46921 ctggataaat ttaggcaaat caacaccaga tgtaacactt acaaaagtat agcttacatg
    46981 atgcggtcta ggcgttactt cccagatacc tgtaaatgtc acacgcttgc cattgtacgt
    47041 cgcattcttc tgatcataac ctttgaaggt ccagacatag tctttttctt cttcgactac
    47101 tgattctaca gcaggttgtt tggctacaat ggtgtcacca accttataag aagcttcatc
    47161 ctttggaagc attcccaaaa tactttgtgg taatggaaca cctgctttag atgatttgaa
    47221 tacatattct ggatttggag taggtaccca gcttccaagg aaagtctgtc tgccttttcc
    47281 tacaacaatt ttttctttat cgtatcctgc aaatgtccaa gtcactttat tcgtcgtatc
    47341 aacataagtc gtttcacttt cttcttgctc tgttgcaaaa gagaccaccg agacctgatt
    47401 ctctgcttta ttctccactt gttcagtagt tgaaagctca tcagcttgag ctacttgagc
    47461 gactccaagc gccgcaggcg caaacaaaag tccaatcgca agggacacag tagcaactga
    47521 caatttgcgg attgaatatt ttatctttct atcctgaaaa aacattccag tcctcctttt
    47581 atttcataat tttcattcta tcataaatag ttaatattag cgattttttt ttgaccgtaa
    47641 agttttaaaa acttatttgt ggatatttcc tcataatata caaatataca aaaaactcct
    47701 tctccaaaat agtaattata gggatttttg taaaaaaatg aaaggactcg ctccctttca
    47761 ttttttgatt ttatttccaa tttaataccg cattcaagcc atagtgatca ctcacttgtg
    47821 gactcttgtt accatcaaat acgacatgta aattttccac cgctaactct ttggtagtaa
    47881 agacataatc gattcgaagg ggttcagtgt tccctttcca gccatcaatt tcaggcggaa
    47941 cagtatagct accacttttc tcttgagcaa cttcaaatgc gtcttgtaag cctaatggac
    48001 tagctaaaat agcttggtaa ccttcctgac ctgctgggtt gttaaaatct ccagctagta
    48061 aaagtggctt gttcaatttt ttcaagacag cctcaaatcg tgcccattct tcttggaaac
    48121 ctttatccca ccaagagaga tgaacactgg caactgctag ctccttgcca tcgactacag
    48181 tttcagctag ggcaacacgg cgagtatgat agtctgttgg atcatccaca tctgaaacca
    48241 aaatttctct ggcttcaata ggtgttttag acaagatagc cacaccttca tggtagcggt
    48301 catagccgat atggttataa gcccaggtcc agtagtaatt tttcccttgc tctaacaact
    48361 tttcaaccaa gagtctaaca taatggtctt ggtgaatagg ctcagctgct ggcaaagctt
    48421 gataaaggtc attaacctcc acctctgacg aggtcatctc ctgattgatt tcttggaaac
    48481 aaatcaaatc atagtccttt tcaagaatat cttcaagcaa aatctggaat ttttcctctg
    48541 cttctttctc catccaactg tgagtattga gtgttaaaaa tttcattctt ttctcccaaa
    48601 ataagaggtt ggaatacagc ttccaacctc aagtatatta caattctact ttagcaactg
    48661 ctgttttagc tgcaagagaa cctgtttttt ctaatttaac tgatttaatt gcatcaccat
    48721 ttgtgaagac aactactgtt gaagtttcac gtcctgctgc acggatagca tccaagtcag
    48781 ctgtgacaag gagatctcct gctgtaactt tttgtccttc agcaacatga actgtaaatg
    48841 gtttaccttc aagacttact gtgtccaaac caatgtgaac caatacttca agacctgctt
    48901 ccgtcacaat accaaaagca tgttttgttg ggaagatgct tgatacagta cctgaaactg
    48961 gagatacaat gtttccattt gcaggttcta ctgcaaatcc atcacccatc attttttgag
    49021 caaatactgg atcctttact tgttccaaag caacaacttg accgtctgct actgagtaaa
    49081 cttcctcagt aagatctttg aagtgaacag tgttttgttg tgcttcagtc atttggcttg
    49141 gaagagtttc aggaatgatt tcacctgaat caaggatatc ttggatatca gatttcaaaa
    49201 tgtcagcttt tggaccgtag atagcttgaa ccccttgtcc tttcatgaca agacccatag
    49261 ctccttctgc tttccattgc tctgcatttc ctactttatc tgcatcttta acagttacac
    49321 gaagacgagt catacatgcg tcaacatcaa cgatgtttac acgtccacca agaaggttga
    49381 taatgtttac agcttgagag cctgctgcaa ctttcacttc actgctggtt tcttctgaac
    49441 cttcagcagt ttcgtagttt ccgttgcgcc ctggagttgc gtagttgaat ttttgaatca
    49501 tgaagtttgc gataaagtac atgattacag caaagagaac agttacccaa acgaagttaa
    49561 cgatatccat accaatacca gcactgattg caataggtgt acgagtcaag aactcgattg
    49621 aaccgaatga gtgcatacgt aggtttacga cgtcagccat agcgaaggca gcaccttgaa
    49681 caagtgagta aacaagatac ataggtgttg cgatgaacat gaacatgtat tcgattggtt
    49741 cagtaacccc tgtcaagaat gttgcaagag ctgttgcaat catcatacct ttgtatttat
    49801 gtttcttgtc agcatcaaca ttacggtaga tagcaacaat cacacccatc aagataccga
    49861 atgaaccgat catttgtcca actttgaaac gagctggatg tactgtatct aacaagtgtt
    49921 gatattgact agcatcagta cctttaaggt ttacaaggtc tgttacccat gcaagccata
    49981 gtgggtcttg accgaatact tgagtacctt tagctgcacc agttaaaatg tcataagtac
    50041 caccaagagc tgtgtagttc attgggatag tcaacatgtg gtgaagacca aatggcaaga
    50101 gcaaacgttc caaagtacca tacaagaatg gtgcaagaat tggagcagtt tcttgtgagt
    50161 tggcaatcca gataccgaag ttattgatac ctgtttgaac tactggccag aaagcagcaa
    50221 gtagaattgc agcgattgct gaacgaagaa taactacaaa tggtacgaaa cgtttcccgt
    50281 tgaagaatga aagtgcatca ggaagtttac ggaagttgta gtatttgttg taagcagttg
    50341 cccctacaaa acctgagata atccctacga atacccccat gttcaaggct ggagcttcaa
    50401 gaacactgat aaagtaatca gcaactttga ttgaaccacc aaagaaagta gttaccatag
    50461 catctggatt tttcaacata tcgcctgata caccaaagat tgtaccagtg atacggttaa
    50521 tcaagatgaa ggcaagacca gcggcgaaag caccaccagc acgttcttta gcccagcttc
    50581 ctccaatggc tagggcaaac aaaatgtgaa ggttaccgat aaccccccaa ccgatttgct
    50641 caagaattcc acctgtgatg acaagtggtg caaaggttgg gttaatcatc acgatagact
    50701 taccgattga aatcatcaaa ccagcagccg gcataaccgc gataactacc atcaaagcct
    50761 taccgaattt ttgccaaaat tcgaaagaca agacattttt gaatgtatct ttcatcattc
    50821 aaatctcctt tatttttatt taggcaaacg ttttacgaaa acgtttgcac tttctatgat
    50881 ttaattatac cactttaatt ttttttgtaa aggcttttat aaaaaaatta cactttttta
    50941 taaaaaattt ctagtgcgcc aaatttcaag ttcaaattag ccatcaagaa gtcttctctg
    51001 ggggacttct ttggaagctc ttttcttctg cgcatctctt ttcaaaaact cttgtagcaa
    51061 aaaaggagat tttacaatct cctcataaaa gcagctattt tacctaaatc ttcaagaatc
    51121 ggcgcatgga tattcctgat cccaatgaac caatgaaaac cccaatcaca aatagtaggg
    51181 caatcatcaa cggactaaat aaatctggac taatcatgga tagattttgc cctaccaacg
    51241 atttgttgac agattggtaa acaatttgat aaacaataaa gaccaaaaca gatggtgcga
    51301 tagctcccaa taaaccgata aaggctcctt ctaacaagaa cggtccacgg atataactgt
    51361 ttttagctcc gaccaagcgc atgatttgaa tttcgcgact gcgggaaata atggtaatac
    51421 gaatggtatt tgaaatcaag aaaactgcga taaaaattaa caaagcagca atccctagtc
    51481 cccaaacacg gataaatgaa gctaacttga agagtctttc tgtattggca ccgccatctt
    51541 gaacctcaga gacaccttca atttttttag catcttcggc tatagttttt acatcatttg
    51601 gagtgtttgc ctctacaata taggcatcat agagaggatt ggcatctcct tcaaagattt
    51661 tccagttatc tcccattatc tcggttaatt tttcatattg ttcttcttta cttgaaaagg
    51721 taacactttt aaccgtagac atgttcttca aagaatcata taccttgtgg tagtcattat
    51781 ttgtaacagt ttgaccttct ttttcaattg tctgactatt atcttccaca tcctttcgga
    51841 tataaactac tacacggaca ttattttcaa tatctgtagc tagtttcgct gtattgaaaa
    51901 taacagatgc aaatattgcc accaaggtca aagtaatcat gactgaactg acagcagcta
    51961 ctgtcatcca accatttcgt ttcaaacttt ttaaggcttc aaataaatgg cgaaaaaatc
    52021 tactaatcat cgtatccata ctctcctttt gattcgtcac gaacgacacg gccattttca
    52081 atggcaatga cacggtggcg caaggtattt acaatctggc tattatgagt cgccatcaaa
    52141 atagttgttc cttgtaggtt aatccgttcc aagagattca taatttccca tgaattatcc
    52201 ggatccagat ttcctgttgg ctcatcagct atcaatactt tgggattatt tacaattgca
    52261 cgcgcaatcg caatccgctg ttgctcccca cctgagagtt catttgggaa agaacgaacc
    52321 ttatgcttca atccaaccaa gtccaaaact tccatcactc gttttttgat attacggcga
    52381 ttttccccga ttacttccat agcgtaagca atattttcat agacagtttt ctttggtaac
    52441 aatttataat cctgaaagac aaccccaaca ctacgacgta gaagcgggac atctttcttt
    52501 ttgatcttaa ccagattaaa accagcaact gataggcttc ctttatcgat ttttacttca
    52561 cgatacagag aacgaataaa agttgacttc cctgctcctg aaggtcctac gatgtaagca
    52621 aattcccccg gttgaacgct gaccgaaaca ccgcgtagag cagtcgttcc gttgtcgtat
    52681 tttttaacga catctctcat ttcaataatt gacatgtgag ttcctttcta tcttagctaa
    52741 ttcgccactt gagataagca tcgataaaac catctaggtc cccatccata accttatcta
    52801 cctgagcaac ctcaaagcta gttcggtgat cttttaccat agtataaggc gtgaagacat
    52861 aagaacggat ttgacttccc caagtaatct cctttttctc acctttgaga gaatctacct
    52921 ccgcagcctt cttctcttgc tccatttgat agagcttagc ctgcaacatc ttcatggcac
    52981 gatctctatt tccatactgg gtacgatcca ctgttgattg gacaacaatt ccagttggaa
    53041 tgtgggttaa acgtacacct gttgaaacct tattgacgtt ttgtccaccg gcaccacctg
    53101 aacggaaggt atccatcttg atatcatctt cacggatttc cacttcaata gtatcatcca
    53161 attctggcat cacttctaca gatgtgaaag aggtatggcg acgtttggca gagtcaaatg
    53221 gtgagattcg cactaagcgg tgaacaccca tttctgactt gaggagacca taggcattag
    53281 gcccttcaaa tgataaagtt accgacttaa taccagcctc atcacctgct tggtaatcca
    53341 acacttccac tttaaagcct ttagcattac cataacgagt atacatacga agcaacatat
    53401 caccccagtc ctgcgcctca gtaccaccag aacctggatg gatttccaag atggcattgt
    53461 tgtggtcata aggttctgac aagagtagag tcatctcgta gctggtcatt atcttatcaa
    53521 gttcggctaa ctgcgctacc agttcatcat gcactgactc gtcttcagcc aaaaaatcca
    53581 ataaaatttc gacttcatcc tgcaactctt ccatcttatg gaaggtattg taagtgtttt
    53641 ttaattcatt caattcttgc gacgtttttt gggccgcaat attatcgttc caaaaatcag
    53701 gttctgtcat cttgttttcc aagatggcaa tctcttcctc tagcccttcg aggtcaaaga
    53761 gaccccctga aagaagctaa tttttcacga tttgcgtcaa ttttctgacg aattactgaa
    53821 atgtccataa atactccttt tttacattat ttcattatag catattttat catttctttc
    53881 catcttttgc tctaatcccc ttttcatgaa aaaagaagcc tttggacttc ccttcttaca
    53941 agacttttgc tgaagtgcga gcgatttctt ccacttgaat accatttgct tcaaattttt
    54001 ctttcaaggc tggtaaatca attgattcat cgatttgcac ttcgataatc accttaccat
    54061 ccttacgcgg aatattgact gtatgggaga tattcaaatt ttcttctaca atcaaagaaa
    54121 caatttttcc aagaacacca acttcatctt ctgtaacaaa gcgtacacga atcccttctt
    54181 cgccataacc tgcaatttca agaaaggctt ggaaaacatc acggtcagta ataactccgt
    54241 atacttgatg gttatctacg acagggagaa taccaatctt atttttcaac atcagataag
    54301 ttgcatcttc tagactagca tagcctgaga cagtgacaac atcgcgaatc atgacatctt
    54361 ttacttttat cttattcaga agataattca tctcatagat agaaagactt gttgctttag
    54421 atggacttgc ttgtgcaatg gttccctcag tcaccaaacc aactaattga tcattttcga
    54481 taacaggcag acggtgcaaa ccttgctctc tcatcaaatc tgctgcatga gatactgttg
    54541 tatctggact aatataaact accttgcggg tcataaaatc tttaactgcc atgagacttc
    54601 tccttttcta ttcttatccc cattatacaa tctttttgta aatctatcaa acgcttacat
    54661 ttctttttcg aaattcaaaa aagtatgaat aagctagcaa aaagagctct gaaatagagc
    54721 tctgtgaatg aaggtaagaa atttttcatt cgattttttc aattattaga aattaagctt
    54781 tcaatgtaga tgcatatttg tttgcaatct ctatccaccg actaaaaagg tcccccggac
    54841 tatattgatg attacttcgt aatcttcatc tgccgactaa aacaatccac tggattgttt
    54901 tagccaccta gatatgcttt tctgacttct tctgatgagg cgagttcttt tcctgttcct
    54961 gataggacga ttttccctgt ttccagtaca tatcctcggt cagagattgc aagtgcttta
    55021 ttggcatttt gttcaatcaa gaggacggtt gttccttgct tctgaatatc ttgaatgata
    55081 tcaaaaatct cttggatgaa gattggggca agtcccattg atggttcatc taaaagaaga
    55141 agttttggtg ttgacataag agcgcgtccc atggcaagca tttgttgttc ccctcctgaa
    55201 agagtagctg catcttggtt cttacgttct tcaagacgag gaaagcgtga gaaaaccttc
    55261 ttcaagttag cttgattttc ttcacgattt ttctttaaga aagctcccat ttcaagattt
    55321 tccataacag tcaagccagg aaagacgtgg cgtccttctg gaacttgtga aagaccacct
    55381 gccacaattt tctgagctgg cattttttgg atttcttgac ctaaaaattc aatctttcct
    55441 gaacttggtc gaaccaaacc tgacaaggtg cgaagaatag ttgtcttacc tgcaccgttg
    55501 gcaccgataa gggaaacaac ttctccttca ttaacttcaa agcttacatc acggactgct
    55561 tggatcatac cgtaatgcac agaaagattt tcaactttta acatagacat taggcttcac
    55621 ctcctagata agcttcgata acgcgtttat tggtcttaat ttcgtctgga gttccttgag
    55681 caattaaacg gccatattca agtacgtaga tacgttctgt tacttccatg accagattca
    55741 tatcgtgttc aatcaacatg attgtaatct taaattcatc tttgatacga cgaattaact
    55801 cagtcaattc ggctgtttcc tgtgggttca tacctgctgc tggttcatct aagaagagaa
    55861 ttttaggttc cgtagcaagg gcacgaacaa tttccaaacg acgttgttgt ccgtaggaaa
    55921 gatttttagc aagagtctct gcatcaccat ctaaatcaaa gattttcaac aattccaaag
    55981 ctttagcctt taattctttt tcactcttgt aaaaagctgg taagcgtaag aaactagtaa
    56041 aaacatgttg tttgtgatgg tttccaaaag caatcaaaac attgtctaaa actgttaaat
    56101 ctttaaagag acggatattt tggaaagtac gtccaagtcc caaagaggca atcttataag
    56161 gtgatttccc attcaaaagg tgaccatcta gagttactgt tccctcgctt ggttcataaa
    56221 caccggccaa aaggttgaaa agggtggttt tcccagctcc gtttggaccg attaatccaa
    56281 ccagttcccc ttcgttcaat tcaagagtca catctccaac agctgttaga ccaccaaaat
    56341 gtttggttaa ctgttttact tcaagtaatg tcattagttt tgttcctcct tcttagattt
    56401 tttaaagaaa cgtgataggc tcagttccca tgttccaagg agtccacctg gtctgaaaat
    56461 cattaccaat accaaggcca aagcgtaaat aatcatacgc acactagtaa catcttggag
    56521 aagcatattc aaaattccca gaacaatagc cgaaacagtc gcacctgtaa tggaaccgag
    56581 tccaccaaat acaacaataa tcaaaacgtt gattgagttg atgaaggtgt aatctttcgg
    56641 tacaacagac ccgataaatc ctgcctgaag tgacccagca atacttgcag taatggcacc
    56701 aaagacaaaa gcgatgattt taattttagt cgtattaacc ccaactgact cagcagcgat
    56761 ttcatcttca cgaacagaga gggttgaacg accaattggg ctacgcaaga agttcaaggt
    56821 tgcaatggtt gtaatcacga caaagaagta aaccatttgc caagttgtaa agttaggaat
    56881 ccctaagata cctgccgcac catttgtaag gcttccacca ttgatgataa agatacggat
    56941 aatttcagaa acacctagag ttgctaccgc aagatagtcc cccttcaagc gcaaggttgg
    57001 aatgccgaca agtaaggcaa ctgctcctga aagcaaagcc cctacaagca tagctccaaa
    57061 gaaggcaccg taggttggtg atttagaacc aataatagct gctgcatagg caccaatcgc
    57121 catgaaacca gcatgaccaa gtgaaaattg tcctgaaaaa ccaacgatta agttgagacc
    57181 aacagccaaa ataatattaa ttccaatttg ttgtaaaatc tgtacataga atagattaag
    57241 tactccgact gaaaccagta cactaatcaa gctatagcca gctaacaaaa ggagtaacca
    57301 tagaatatta acttttaaat tttccttcat cgtttacacc ttctctttca cattcttacc
    57361 aaggatacca gctgggcgga caatcaagat caacaacaag attccataaa caatggcatc
    57421 acggaaatct gacatcccaa aggctgtcgc aaaggtttcc aatagaccaa tcacaaagcc
    57481 accaagagcc gcaccaggaa taattccgat accaccaagt actgcggcaa cgaaagattt
    57541 aagacctgga gtaaccccca tcaaaggctc aagagagtta taataaagag caatcagaac
    57601 accagccgca cccgcaagag cagaacccaa agcgaaggta aagctaatcg tacggtttac
    57661 attgatcccc atcaattgtg ccgcgtcgct atctactgat actgcacgca tggctttccc
    57721 catcttagtc ttttggacaa tgacttgtaa caaaatcatc aaaatcaagg aaatggccaa
    57781 aatcattaac tgcacatttg ttaagctaat tggtcccaaa tcatatcgaa ctgtttgaat
    57841 cgcttgaggg aaggcacggg tattggcacc aaccagatag accattccat actccaatag
    57901 gaaagaaacc ccaatagccg taatcaaaac agcaatacga gtagagtggc gcaaaggtcg
    57961 gtaagcaaga aactcaatca cgacaccaag aatagctgtc actagcatag ctacaataag
    58021 cgctacaaag aaattcattt ggaaagaatt gatcaagaaa taaccgataa aggctcccat
    58081 catataaata tcaccatggg cgaagttgat gagcttgata attccgtaaa ccatggtata
    58141 tcctagggct aacagcgcgt aaacactacc tagaatcaaa ccatttacga gttgttggag
    58201 cataagattc actctttcta tttataattc cgagggtttt ccctcacttt ttgataggtt
    58261 cttatactca atgaaaatca aagagcaaac taggaaacta gccgcaggtt gctcaaagca
    58321 ctgctttgag gttgtagata agactgacga agtcagtcac atatataatc caaggcgacg
    58381 ttgacgcagt ttgaagagat tttcgaagag tattaaatat cgaaacaggg agtgagtcaa
    58441 aggctcattc cctatttcaa catttttcta ttatggtttt acaacttctg ctgcttcaac
    58501 tttaccattg ttcatggtca tcatgtaagc agttttgact gtgttgtggt ctgcatcgaa
    58561 gcttgtttga ccagttacac cttcaaaatc ttttgtttta gcaaggttat tcttgatttc
    58621 acctgaattt ttagcacctt ttgctgcgtt tgctacaagg tgaactgaat cataagccaa
    58681 ggctgcaaat gttgaaggct cttcattgta cttagcacgg taagcgtcaa ggaaggcttt
    58741 agctttagct gaaacttcta cagtagttga gaagcctgag ataaagtaga tgtttgatgc
    58801 tttttcagca gttgcttgtt gtacaaactc ctcaccgttg aatccatcac caccaacgat
    58861 tggtttgtca attcccatac cacgcgcttg gtttacaatc ttaccagcct cattatagta
    58921 accaggaaca acgatagcat caaagtcttt ccctttcatt tttgtaaggg ctgcttggaa
    58981 gtctgtgtca cctgctacga aagtttcatc tgcaacgatt tcacccttgt atgactcgcg
    59041 gaaagatttg gcaatccctt tagcatagtc actggcattg tcagtgtaaa gaacaacttt
    59101 cttagcattt aatttttcag aaacatagtt tgagataatt tttccttgga agctatcttg
    59161 gaaagttcca ataaagaggt aatcttgacc tttagtcaat ccatcttgag tcgcacttgg
    59221 tgagatcaat ggaacacctg cttttgtagc gttcgctacc gcagctgcag tcgcaccaga
    59281 tgtcgcaggt cctacgactg ctgatacttt agattgggtt acaaggttag ttgtaactga
    59341 agcagcctca gctgtttcag acttattatc tttatcgact acttcgattt gttttccatc
    59401 gataccacct gcggcattga tttcatcaac agccaattgg gcaccttttt gttcagctgt
    59461 tccgtatgca gctaaagaac ctgattcttc aaagttaaac ccgattttaa ttgtcttttc
    59521 ctctactgag ttaccagcag tgttgactgc tccagacttc acttctccac aggctgcaag
    59581 aagtgctaca cttgcaagcg ccacaaacga tagggcaaat tttttcttca tctttttgtc
    59641 tccttatttc ttaaatagtc tattaagaat agaccgaatt atcagaaaat tgtcaatgtt
    59701 ttccttgaac tttttcgatg ataacgtttt cctatcgata aagattgccc acaaagggtg
    59761 tttccaactc ttggatatga caaaccctaa cttttttaat aaatttttcc ttgctcaagc
    59821 gtccgaccaa ttgctccact tcttgagttg gaacatagag ttgtaagtaa cgatgtttct
    59881 tggaatgata ggtaatatct ccataatcct gcagtttttt ggcatcacga ttatagtaaa
    59941 gatagataat caagccagag cgattgactt tttcaaacat gataaatcct ctttctaaga
    60001 aatctctccc tattatacca aaaaaagcaa acccagtcga gtttgccttc tatcatcatt
    60061 agttcaatga attgttggcc ataatttcat caataaagcc atattcaagt gtttcctggg
    60121 cgctcatcca gttatcacgt tctgcatctg catggacttt ttccattgac tgacctgaat
    60181 tttcagccaa gattttttcc aaggtattac gagttttgag caagtgttct gcagcgatag
    60241 ccatatcagt ttgttgggta ccaccacctg taccgcccat tggttggtga atcatgtatt
    60301 cagcatttgg aagcatgaaa cgtttgcctt ttgccccact tgatgcgatg acagtcccca
    60361 tagatgcagc cattcccata acaatggttt ggacatctgc cttgataaag ttcatggtat
    60421 ctacgattgc caaaccagct gaaacagaac cacctggtgt attgacataa aggtaaatat
    60481 ctttcgtact atcttgggca tccaagaaaa gcaattgggc aataacagag ttagccatat
    60541 tgtcttcaac cggacctgtc agcataatga tgcggtcttt gagaagacgt gagtaaatat
    60601 cgtaagaacg ttctccacgg cttgtttgtt caataactac aggaatcatt catttctcct
    60661 tttgagtttt aattttgttg gtcaaatgac tgaagataag actattataa tatcttggtc
    60721 aaaaaaggtc aaatttttgc tctgctttca ttagacagaa acaaaaaccc aacctccttt
    60781 cgtgactaga aatacttttc caagtcattc ttcttttcga tcttattttg taccgaacaa
    60841 gcggtctcca gcatctccaa gacctggaac gatataaccg tgttcgttca aacgttcatc
    60901 caaggctgct gtaaagattt ctacatctgg atgagcttct tgaagggctt ttacaccctc
    60961 tggagcagat acaaggcaga caaatttgat atttgatgcg ccacgttttt taagagaatc
    61021 aacagccaag attgctgagc cacctgttgc caacattggg tctactacaa aaatttgacg
    61081 ttggtcaatg tcctcaggca atttcaccaa gtattcaact ggttgaagtg tttcttcatc
    61141 acggtacata ccgatgtggc caactttagc agctggaacc aagctcaaga gaccatcaac
    61201 catcccgata cctgcacgca agattgggac gatggccaat ttcttacctg ccaattgttt
    61261 ttgaactgtt tttgtaattg gtgtttcgat ttccacatct tctagtggaa gatcacgaag
    61321 tacttcatac cccatcaaca ttgcaatctc atctactagc tcacgaaaag cttttgtaga
    61381 agtatctgta cgacgcaaga ttgacaattt gtgttgaatc agtgggtgat taataacttc
    61441 aatttttccc atttttggaa ttccttcttt caatttattc ttcttattat accaaaaaac
    61501 ggtttaaaaa tctttctaag ccatttattt ttgataattt ttacattaga tcagcctctt
    61561 taagagctgt ctgtactgtc tcaagtggta aatgggtcaa ttctgtccct ttttcttgat
    61621 aaaggtattg ggcgtagtcg tccattcggt actggttgat ataaaccacg cgcttgcagc
    61681 cgacctgaag caattgtttt gtacagttga gacaaggaaa atgggttaca taggctgtaa
    61741 agcctttggg aacaccacgc tcagcacctt gaaggatagc attgacctca gcgtgaaggg
    61801 tgcgaacaca gtggccttca atgaccaaac attcgtgatc aatacaatgc tcagtccctg
    61861 acaccgaacc attgtaacca gtggaaataa ccttattatc ttttaccaga atcgcgccca
    61921 ctttagcacg tttacaagtg gaacgattcg caattagtag ggcttgggct gcaaaatact
    61981 catcccaggc cagtcttttt tcagtcatct cttttctcct ttttctctat tttttaaaaa
    62041 atggtaaacc taaatctgca atcttttcag ctggtacctt catgccatcc ttgatccatt
    62101 ttagaaggac agagacgatg gctgagctcc agaaggaatg aagataagag ctgacacctt
    62161 ttgatttccc atggtatttt tctagaaatt cctgcatggc ttggacaaag attttttcca
    62221 gatggtaatc caaggccaat tgaattactc tagcttcctt tctggcctcc cggaaaaggt
    62281 gaacccaaac caaataaagg tctgtcttta aatcgtaatg atgcagctgt tccataatat
    62341 tgtggacagt tcgtttaaag acgctctcta aaatttcctc tttggagtca taattgcgat
    62401 aaaaggccgc acgcgaaaca cctgcacgtt tgaccaattc agaaatacta atcttggtca
    62461 gctccttttt ttccaagagt tgcaagaggg ctgtttcaat ggcttctctg gttaataaat
    62521 tggattcttg gtttgatttt ctgagatttt caagagactt ttcagagatt ctacgttcag
    62581 acataacatt ttctttctac ttgtcacaac agacggatga tgcttttgtt tcaagagttt
    62641 tcatgatata attgtaaaaa aagacagaac ctttgtcaat gtataactga caaagatgga
    62701 gaatttctat gacttggaag attattgctg actctggttg tgattatcgt caactgccaa
    62761 caccagctat taacacaacc tttgtaagtg tccccttaac cattcaagta gctgatcagg
    62821 tctttgttga tgacgccagt ctcgatattg accaaatgat ggaaaccatg tatgcaactg
    62881 cagaagcttc aaaatcagct tgtccaagcc cagatgacta tttgcgagca tttgaaggtg
    62941 ccaaaaacat tttcctagta accatcacag gtaccctttc tggcagtcac aatagcgctc
    63001 aactagcaaa gaatatttat ctggaagacc atcctgacac taagattcat gtgattgata
    63061 gtttatctgc tggtggtgaa gttgacctac tcgtagaaaa attgaatgac ttgattgacc
    63121 aaggcttgtc ttttgaagaa gtggttgaag ctatcaccgc ctatcaagaa aaaactaagt
    63181 tgctctttgt cctagccaaa gtcgataact tggtgaagaa cggccgtttg agtaagctta
    63241 tcggtacggt agttggcctt ctcaacattc gtatggtcgg aaaagctagt gaaactggaa
    63301 ctctcgaatt gctacaaaaa gcaaggggat caaagaaatc agttcaagct gcctatgatg
    63361 agttagtaaa agctggatat gctggtggcc gtattgtcat ggcccaacgc aataacgaaa
    63421 aatgttgtca acagctctca gagcgaatcc gtgaaacctt cccacaagcg gatattaaaa
    63481 ttctaccaac ctctggtctc tgcagtttct atgcagaaga gggcggtttg ctgatgggct
    63541 atgaaattga ttaattgcat tcttgacaag aggtgaccat catctcttgt ttttttgtgg
    63601 tacaatagag ctatgaaaca ttttgatact attgtcatcg gtgggggacc tgctggtatg
    63661 atggctacga tttccagtag cttttatgga cagaaaaccc tcctcatcga aaaaaatcgg
    63721 aaacttggaa aaaaattagc tgggactggt gggggacgtt gcaatgtgac caacaatggt
    63781 agcttagaca acctgctagc tggaattcct ggaaacggac gctttcttta cagtgttttc
    63841 tcccagttcg ataatcatga catcatcaac ttttttacag aaaatggtgt taaacttaag
    63901 gtcgaagacc acggacgcgt ctttccagcc agtgacaagt ctcggactat tatcgaagct
    63961 ttggaaaaga aaatcaccga actaggtggt caagttgcta ctcaaataga aatcgtttct
    64021 gttaaaaaag tagatgacca gtttgtcctt aagtcagcgg atcaaacctt cacttgtgag
    64081 aaactcattg tcacaacagg tggtaagtct tatccttcga ctggttcgac tggttttggt
    64141 cacgagattg ctcgccattt taagcatacc atcaccgatc ttgaggctgc tgaaagtcct
    64201 ttattaacag attttccaca taaagcctta caagggattt ctctggacga tgtgacccta
    64261 agttatggta agcatgtcat cactcatgat ttactcttta cccactttgg tttgtcaggt
    64321 cctgctgccc tacgcatgtc tagctttgtc aaaggtgggg aggttctctc actcgatgtt
    64381 ttgcctcaac tttctgagaa ggacttggtt acatttctag aagaaaatcg ggaaaaatcc
    64441 ttgaaaaacg ctttaaaaac cttgttacca gaacgcttgg ccgaattttt tgtacaagga
    64501 tatcctgaaa aagtcaaaca actgactgaa aaggaacgag aacaacttgt ccagtccatt
    64561 aaagaactta aaattcctgt aactggaaaa atgtcccttg caaagtcctt tgttaccaag
    64621 ggtggagtca gtctcaagga aatcaatcct aaaacccttg aaagtaagct ggtacctggc
    64681 ctccactttg caggcgaagt tatggatatc aatgcccaca cgggtggctt taacatcact
    64741 tctgccctct gtaccggctg ggtggcggga gcaaatccaa tctaaatata cattactaaa
    64801 tggaacaatc cccccaaaaa aagaaaggaa ctactttgga acatattatc ttgctaaggg
    64861 gagtcactcc taatggaaaa aatgctatcc ctaaaatgtc ttatctagta gatatcttga
    64921 cagaagctga ttttcaacaa gttcgaactt atattcaaag tggaaatatt attcttgaaa
    64981 gtaacttagc tctcgaagaa atacgagaac aggttcatac tctattagac ttcctgcaaa
    65041 actagaatcc tagttcatga ttgataatac cagca
//
LOCUS       DAVKXA010000004        63177 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKXA010000004 DAVKXA010000000
VERSION     DAVKXA010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.004"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            400..582
                     /locus_tag="VW883_000289"
                     /pseudo
     CDS             400..582
                     /locus_tag="VW883_000289"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1195..1479
                     /locus_tag="VW883_000290"
     CDS             1195..1479
                     /locus_tag="VW883_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273486.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1472..1710
                     /locus_tag="VW883_000291"
                     /pseudo
     CDS             1472..1710
                     /locus_tag="VW883_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1806..2024
                     /locus_tag="VW883_000292"
     CDS             1806..2024
                     /locus_tag="VW883_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273487.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2396..4720)
                     /gene="pflB"
                     /locus_tag="VW883_000293"
     CDS             complement(2396..4720)
                     /gene="pflB"
                     /locus_tag="VW883_000293"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0273488.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5115..6176
                     /gene="dinB"
                     /locus_tag="VW883_000294"
     CDS             5115..6176
                     /gene="dinB"
                     /locus_tag="VW883_000294"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0273489.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLRIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(6323..7168)
                     /locus_tag="VW883_000295"
     CDS             complement(6323..7168)
                     /locus_tag="VW883_000295"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0273490.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            7424..8292
                     /locus_tag="VW883_000296"
                     /pseudo
     CDS             7424..8292
                     /locus_tag="VW883_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8593..10482)
                     /locus_tag="VW883_000297"
     CDS             complement(8593..10482)
                     /locus_tag="VW883_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0273491.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSRSGSSGGGFSGGGGGG
                     SIGAF"
     gene            10620..12185
                     /locus_tag="VW883_000298"
     CDS             10620..12185
                     /locus_tag="VW883_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0273492.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            12185..12925
                     /locus_tag="VW883_000299"
     CDS             12185..12925
                     /locus_tag="VW883_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0273493.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(13034..13249)
                     /locus_tag="VW883_000300"
     CDS             complement(13034..13249)
                     /locus_tag="VW883_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273494.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(13984..15234)
                     /gene="ilvA"
                     /locus_tag="VW883_000301"
     CDS             complement(13984..15234)
                     /gene="ilvA"
                     /locus_tag="VW883_000301"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0273495.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(15284..15640)
                     /locus_tag="VW883_000302"
     CDS             complement(15284..15640)
                     /locus_tag="VW883_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0273496.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(15878..16114)
                     /locus_tag="VW883_000303"
     CDS             complement(15878..16114)
                     /locus_tag="VW883_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273497.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(16221..17243)
                     /gene="ilvC"
                     /locus_tag="VW883_000304"
     CDS             complement(16221..17243)
                     /gene="ilvC"
                     /locus_tag="VW883_000304"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0273498.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(17309..17785)
                     /gene="ilvN"
                     /locus_tag="VW883_000305"
     CDS             complement(17309..17785)
                     /gene="ilvN"
                     /locus_tag="VW883_000305"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0273499.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(17778..19478)
                     /locus_tag="VW883_000306"
     CDS             complement(17778..19478)
                     /locus_tag="VW883_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0273500.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(19678..21345)
                     /locus_tag="VW883_000307"
     CDS             complement(19678..21345)
                     /locus_tag="VW883_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0273501.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(21348..21713)
                     /locus_tag="VW883_000308"
     CDS             complement(21348..21713)
                     /locus_tag="VW883_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0273502.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(21870..22058)
                     /locus_tag="VW883_000309"
     CDS             complement(21870..22058)
                     /locus_tag="VW883_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0273503.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(22174..22659)
                     /locus_tag="VW883_000310"
     CDS             complement(22174..22659)
                     /locus_tag="VW883_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0273504.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(22928..24472)
                     /locus_tag="VW883_000311"
     CDS             complement(22928..24472)
                     /locus_tag="VW883_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0273505.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKTKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            24685..24987
                     /gene="gatC"
                     /locus_tag="VW883_000312"
     CDS             24685..24987
                     /gene="gatC"
                     /locus_tag="VW883_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0273506.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            24987..26453
                     /gene="gatA"
                     /locus_tag="VW883_000313"
     CDS             24987..26453
                     /gene="gatA"
                     /locus_tag="VW883_000313"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0273507.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            26453..27895
                     /gene="gatB"
                     /locus_tag="VW883_000314"
     CDS             26453..27895
                     /gene="gatB"
                     /locus_tag="VW883_000314"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0273508.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LDGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            28024..28584
                     /gene="efp"
                     /locus_tag="VW883_000315"
     CDS             28024..28584
                     /gene="efp"
                     /locus_tag="VW883_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0273509.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            28606..28995
                     /locus_tag="VW883_000316"
     CDS             28606..28995
                     /locus_tag="VW883_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0273510.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            28988..29410
                     /gene="nusB"
                     /locus_tag="VW883_000317"
     CDS             28988..29410
                     /gene="nusB"
                     /locus_tag="VW883_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0273511.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(29460..29696)
                     /locus_tag="VW883_000318"
     CDS             complement(29460..29696)
                     /locus_tag="VW883_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0273512.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(29709..30182)
                     /locus_tag="VW883_000319"
     CDS             complement(29709..30182)
                     /locus_tag="VW883_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273513.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(30200..30385)
                     /gene="briC"
                     /locus_tag="VW883_000320"
     CDS             complement(30200..30385)
                     /gene="briC"
                     /locus_tag="VW883_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0273514.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(30544..31311)
                     /locus_tag="VW883_000321"
     CDS             complement(30544..31311)
                     /locus_tag="VW883_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0273515.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(31308..32174)
                     /locus_tag="VW883_000322"
     CDS             complement(31308..32174)
                     /locus_tag="VW883_000322"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0273516.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(32211..33578)
                     /gene="accC"
                     /locus_tag="VW883_000323"
     CDS             complement(32211..33578)
                     /gene="accC"
                     /locus_tag="VW883_000323"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0273517.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIVTVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(33590..34012)
                     /gene="fabZ"
                     /locus_tag="VW883_000324"
     CDS             complement(33590..34012)
                     /gene="fabZ"
                     /locus_tag="VW883_000324"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0273518.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(34009..34494)
                     /locus_tag="VW883_000325"
     CDS             complement(34009..34494)
                     /locus_tag="VW883_000325"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0273519.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(34497..35732)
                     /gene="fabF"
                     /locus_tag="VW883_000326"
     CDS             complement(34497..35732)
                     /gene="fabF"
                     /locus_tag="VW883_000326"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0273520.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(35754..36485)
                     /gene="fabG"
                     /locus_tag="VW883_000327"
     CDS             complement(35754..36485)
                     /gene="fabG"
                     /locus_tag="VW883_000327"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0273521.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(36519..37439)
                     /gene="fabD"
                     /locus_tag="VW883_000328"
     CDS             complement(36519..37439)
                     /gene="fabD"
                     /locus_tag="VW883_000328"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0273522.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(37432..38406)
                     /gene="fabK"
                     /locus_tag="VW883_000329"
     CDS             complement(37432..38406)
                     /gene="fabK"
                     /locus_tag="VW883_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0273523.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(38525..38749)
                     /locus_tag="VW883_000330"
     CDS             complement(38525..38749)
                     /locus_tag="VW883_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0273524.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(38809..39783)
                     /locus_tag="VW883_000331"
     CDS             complement(38809..39783)
                     /locus_tag="VW883_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0273525.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(39783..40217)
                     /locus_tag="VW883_000332"
     CDS             complement(39783..40217)
                     /locus_tag="VW883_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0273526.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(40311..41096)
                     /locus_tag="VW883_000333"
     CDS             complement(40311..41096)
                     /locus_tag="VW883_000333"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0273527.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            41421..42785
                     /locus_tag="VW883_000334"
     CDS             41421..42785
                     /locus_tag="VW883_000334"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0273528.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEDNEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            42788..43159
                     /locus_tag="VW883_000335"
     CDS             42788..43159
                     /locus_tag="VW883_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0273529.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            43373..44647
                     /gene="serS"
                     /locus_tag="VW883_000336"
     CDS             43373..44647
                     /gene="serS"
                     /locus_tag="VW883_000336"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0273530.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(44672..45571)
                     /locus_tag="VW883_000337"
     CDS             complement(44672..45571)
                     /locus_tag="VW883_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0273531.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEMAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(45681..46229)
                     /locus_tag="VW883_000338"
     CDS             complement(45681..46229)
                     /locus_tag="VW883_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0273532.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(46447..47769)
                     /locus_tag="VW883_000339"
     CDS             complement(46447..47769)
                     /locus_tag="VW883_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0273533.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITSLVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(47860..47948)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(48112..50448)
                     /locus_tag="VW883_000340"
     CDS             complement(48112..50448)
                     /locus_tag="VW883_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0273534.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(50552..51100)
                     /locus_tag="VW883_000341"
     CDS             complement(50552..51100)
                     /locus_tag="VW883_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0273535.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(51097..51399)
                     /gene="zapA"
                     /locus_tag="VW883_000342"
     CDS             complement(51097..51399)
                     /gene="zapA"
                     /locus_tag="VW883_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0273536.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            51486..52367
                     /locus_tag="VW883_000343"
     CDS             51486..52367
                     /locus_tag="VW883_000343"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0273537.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQVLLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            52371..52985
                     /gene="lepB"
                     /locus_tag="VW883_000344"
     CDS             52371..52985
                     /gene="lepB"
                     /locus_tag="VW883_000344"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0273538.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            53113..55479
                     /locus_tag="VW883_000345"
     CDS             53113..55479
                     /locus_tag="VW883_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0273539.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(55527..56810)
                     /locus_tag="VW883_000346"
     CDS             complement(55527..56810)
                     /locus_tag="VW883_000346"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0273540.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(57616..58752)
                     /locus_tag="VW883_000347"
     CDS             complement(57616..58752)
                     /locus_tag="VW883_000347"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0273541.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQRTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(58814..59251)
                     /locus_tag="VW883_000348"
     CDS             complement(58814..59251)
                     /locus_tag="VW883_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0273542.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(59253..61208)
                     /locus_tag="VW883_000349"
     CDS             complement(59253..61208)
                     /locus_tag="VW883_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0273543.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKILFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(61232..63001)
                     /locus_tag="VW883_000350"
     CDS             complement(61232..63001)
                     /locus_tag="VW883_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0273544.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVVQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHINVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        18940 a        14006 c        11772 g        18459 t
ORIGIN      
        1 tatatgaaat tctcattttt gtttttacaa ttctccttag ttaaatcttg tttaatatat
       61 gttttacata tagtatttag cgccacatag tactgaactc tctccaaaaa cggttattcc
      121 tctttgaata gggcgttatc acaagaaaag catctccacg tttcaacttc atatggctca
      181 aaaacaatca attgatgcta aaacctgtac ctagatgttt cggttcataa aaccatgaaa
      241 ctgtaaaagt ggatgaaatt gatagcgata gtcaaatcaa gaggcatcat aactctaaaa
      301 agtcacaata tataagttca tcctcggaaa aatatcattc taattgttga aatgcctaca
      361 tgaaaagaaa cgtcaaatgc tcatgaaaca acgaatacag gtatcaaaac tatgacaaaa
      421 caagtcccta aatttactaa agacactgct caactttaca cctgtaaatg gttgttgtat
      481 aataaagtta caaagatgta cgaccacact gttgtaaatc atagtgttcg cgaatatatt
      541 actgatagca tttctacaaa tacaattgaa gagactggat aggctttaaa cgaaatatgt
      601 cagtgttttg gcattcctag tcttcatatc atttaaagaa ttgtatagac aaaatttttt
      661 tccaatacag acactcgtaa caactgcttc atttttctac caacatattt aggaacagga
      721 taagatagaa gaagattaat ccatagctca gttctatacc aatctaagac aaataagcta
      781 aaaaaacgat tgataataag caaatagatt ccaaattttc tctatctgct cattttaata
      841 aacaatacta gtgtaactat ccttccagtc agaaacttgt caaatcacac cgaaaactct
      901 tctaaaattt atctcgttag gcaatcaagc aaaaactcga cgatagtaca aacattatca
      961 tacagaattg actgcctaaa ttatatactt tagtaaggtt ttcggataag aaaaaaggtt
     1021 cattttacat ttctaaacat tcttttctaa gatgaaaaac agaatttttc gattgtgatt
     1081 taaagcaaca agaagatttt cagtatcatc ctatagatac gagctaatta agaaaaacta
     1141 catttttgaa tataaactac aataatataa actaaatttt ataggaggaa gacaatggat
     1201 tggtacgatt atatgataca ggcatccaaa caatcacaat tcaacgcaag ccattggttt
     1261 cgctatttgc gaaaagttat ttttgaagac tattcttatt taacaaacca agatgtagaa
     1321 aagttgctag actccaaaga actaacccgt tttcaaaaaa ttagcttgaa gtatgccttt
     1381 caagagcata ctccaactca taaatatgtg atttcattaa ataaacctgc taagttaacc
     1441 aatgttcaaa aattgatgga gaaatacaaa catggataaa atgaaaccgg tcttccaagc
     1501 cctaaataag aaattaattc aggaaaatct gactttaaca attatggtta tgtcttagaa
     1561 tatcatggtt tacgtgccac acaagatgtt gatgcttttt atgaccaaaa tcagaaaatc
     1621 aatgaaatta ttgctcgtgt aggaaaacag tttaatctta acatccacga agagttatgg
     1681 ctcaacaatc atgttgcaaa gcaaatatga acaaacaacc tcccttaagt ttatgcgaat
     1741 ccttgtactc atttgagaat ctgaccgttt tagtagtccc tattgagtat gtgttaggaa
     1801 tgaagatgat gagtatcaga gagcaggatt tgcaagatat tggtgcaatt attaaataca
     1861 aaaactttca ttcaccattc gataccttta aatatttaaa agacatggga tttgatacta
     1921 ttgacctctc tgttctatta gaaggtttta gttatgctta tggtatggat tggttagaaa
     1981 aattttttaa agaaaatcaa gataaacttc gcgaatttta ttaacagtat caaacaagat
     2041 gattgtcaat tagccagtcg tcttattttt atgatgaaat gaaatgaaat aaaatcggaa
     2101 caaatcactt agagaattcc agtcaatttc tagcactgtt tgagccgttt cagcggacta
     2161 tagtaaaatg aaataagaat aggacaaatc gatcaggaca gtcaaatcga tttctaagaa
     2221 tgttttagaa gtaaaggtgt actattctag tttcaatcta ttatatttca gattcggtcc
     2281 actgttcctt cccaaaaaca ttgcatattg cgccgaagga attgctcaca ctatcccaag
     2341 cacaaaaccc tcagtcgatt gaccgagggt tccttttcat tattcaaaaa cttgattagc
     2401 tcaatgcatc caaggcatca tccattgaaa gaacttcgtg gaagacacgt tgtgtcaatt
     2461 cagttttttg ttctggagtg aggtatttag tatttacaca gtatccagag atacgtacga
     2521 taacgtcttc acctgacatg attttttcgt aaacatcgtt caagtccata acgttcaagt
     2581 taacgtgttg tccaccgttt tcgaagtaac catcaaggat tgttaccaag ttatcaactt
     2641 gttcatcacg agtcttacca agagcgcgag gtgatacttg tgtagtcaat gagataccgt
     2701 cagctgcata actaaagtca aggctagaaa gtgagttcaa gttttgcaac caaccacctt
     2761 tagctttgtt agatgggtta gcacctggtg agaagaattc aagtttagac aagttcacag
     2821 aaccatcttc gttgaggtat acacctttgt gaactggtga gttaccagtt tgtttagagt
     2881 aagcaacgtt agatgtgatt gtcaaaagtg atactgtagc ttctgcgtct ttgtatagtt
     2941 tgtggctacg tagacgagtt gtgtaagctt cgatcaacca ttctgccaat tcgtttgaac
     3001 gtgggtcatc ttcaccccag cgtgggtagt caccgattgt ttcgtaatcg tagatgtagc
     3061 catcttcgtc acggattggt ttaactgtag cgtatttgat agctgacaat gtatcaacag
     3121 tgttagcaaa tccacagata ccgaatccca tgttcgcacg ttgtttagtt ggcaagaagg
     3181 ccatttgaac agcttcgtag ttgtacctat cagtcatgta gtggatgatg ttcaaggcat
     3241 ctacgtaagt gtcagtcaac cagtcaagag atttttcaaa gttcgcttta actgattcaa
     3301 attcaagaac ttcgtcacgg attggttcga tatcaaatac tttgtagtct ttgtgaacat
     3361 cgtcgtaacc accattcaaa ccagtaagaa gggctttaag aacgtttaca cgagcaccga
     3421 agtactggat gttgtggcgt tgttcttcat tttctggatc aagtggagac acacagcatg
     3481 agatacagct catttcacca tatccgtctt tagccattgt tgttacacct tcgtattgga
     3541 tagaagagtg tttgtggctc atgtgcatac agtagcgacg gaagttgtat ggcaatttgt
     3601 cagtccaaag aactgtcaag tttggttctg gtgagttacc gatgttgtca agagtgttca
     3661 agaaacggta gtccatctta gtaacacggt gacgaccgtc gttacccata ccagccatag
     3721 aagttgtgat aaaggttggg tcacctgagt acaattggtc ataagctttg gtacgagcaa
     3781 atttaactgt acgaagtttc ataacgaaat catcaacgaa ttcttggatt tctgattcag
     3841 taaatgtacc acgagcaagg tcacgttctg caaagatgtc caatacgatt ggtacacgac
     3901 ctagagatgt agcagcaccg ttaatcacac ggcagacagc catgaaagca atgttaaccc
     3961 attggattgc ttctttcacg ttcatcgctg gtttgcgaac atcaaccccg taaaggtcac
     4021 ccaggcgaac aacttgttgc aatgcttggt attgaaggtt tacttcttca cgaagacgga
     4081 ttgtttcttc atcgatttct ttgattgcat tccagtcgtt tactttttct tgcatcaagt
     4141 agtctgcacc gtaaagagca agacgtgcgt aaacaccgat gatacgtccg cgtgagtatg
     4201 catctggaag accagttaca gtgtgtgcat gacgagcgcg acgaatattt gaagtgtagg
     4261 cacggaaaat accgtcgtta actgttgtta catatttagt gaagatttcg tgaacagctg
     4321 ggtctggttc gtatccattt tcttttaaag tagtttcagc catacggata ccaccttttg
     4381 gcatgaagtt caatttgaag agttcatcat tttggatacc aaagataact tcattttctt
     4441 tgtcgataaa tccagcaggg atatcagcga tagatgttgg acgagtgtcc attgggaaac
     4501 gagtttcttc gtagtgtgct ttagtttctt ctacaatttt cttgatgtga agtgaacgct
     4561 ctgttggtcc tgcaaggaag ctttcgtctc catcataagg tgtgtagtta gcttgtacaa
     4621 agcgtgatac acttgctttt tctttccaat ctacgccttt gaagccttcc caagctttgt
     4681 caaaaatatc ttgtgcttca acaactgtct taacaaccat attaatgtcc tcttttttct
     4741 agtaacagtc atctgttaca ttcataagac aagtatacca taaagtaacc gatttcaaca
     4801 agtgcaaaat ccctattttt acactttctt ttctaaaaca gtctatattt tatttcaaac
     4861 tgtattatat ttttgaaaaa aataaagtcc ttttttcttt ttttcagaaa aaagggtata
     4921 ataaaagaaa ataagcagta acactcaatg gaaatcgaaa agcaaactag gaagctagcc
     4981 gcaggctgct caaagcactg ctttgaggtt gtaaatagaa ctgacgaagt cagctcaaaa
     5041 tactgttttg aggttgcaga tggaagctga cgtggtttga agagattttc gaagagtata
     5101 aaaaggtgct aggcatgttg atttttcctt tgttaaatga tttgtcaaga aaaatcatcc
     5161 atattgacat ggatgccttt tttgctgcag tggaaatcag ggataatcct aaactcagag
     5221 gaaaacctgt cattattgga agcgaccctc ggcaaacagg tggacgggga gtcgtttcta
     5281 cctgtagtta tgaggcaaga gcttttggtg tccattctgc catgagttcc aaggaagctt
     5341 atgaacgttg tccccaggct gtctttatct cagggaatta tgagaaatac aagtctgtgg
     5401 gactccggat tcgagctatt tttaagcgct atacagattt gattgaaccc atgagtattg
     5461 acgaagccta tttggatgtg acagaaaata aactcggtat caagtcagcg gtcaaaattg
     5521 ctcgcctcat tcaaaaagat atctggcaag aactccatct aactgcttct gccggtattt
     5581 cctataacaa gttcttagct aaaatggcga gtgattatca aaaacctcat ggtttgacag
     5641 tgattctacc tgaacaggct gaggattttc tcaaacaaat ggatatttcc aaatttcatg
     5701 gagtaggaaa aaagacagta gaacgtcttc atcaaatggg tgtttttact ggtgctgatt
     5761 tacttgaagt tcctgaggtg accctaatag accgttttgg tagactaggc tatgatctgt
     5821 atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa
     5881 tcggcaagga gaaaacctac gggaagattc tccgtgctga ggaagatatc aaaaaagagc
     5941 tgactcttct atcagaaaaa gtcgctctca atctacatca acaagaaaaa gctggaaaaa
     6001 ttgtcatttt gaaaatccgc tacgaggact tttcaactct taccaaacga aaaagtattg
     6061 ctcaaaaaac acaagatgct agtcagataa gccaaatagc cctgcaactc tatgaagaat
     6121 taagtgagaa agaaagaggt gtccgcctat tggggattac catgactgga ttttaaagct
     6181 caatgaaaat caaagagcaa actaggaggc tagccgcagg ctgctcaaaa cactgttttg
     6241 aggttgcaga taaagctgac gcggtttgaa gagattttct aagagtataa aaccttgaag
     6301 agttgcccct tcaaggtttt tcttatacaa ataaacggac aaaactgtaa agtagcaaaa
     6361 cactaccaag cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc
     6421 tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc tactcccatc gcgaccaaga
     6481 gcaaaaacaa ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg aaaatcttta
     6541 aggcactagc tccaaacata acgggaatcc caagatagaa ggtaaattct gtcacaactg
     6601 aacgactggt tccatttaac aaaccaccga caatcgttgc acctgaacgg ctagtccctg
     6661 gtaaaagagc aagaacttgg aagagtccga tatagaaagc ggtcgtataa ggaagcttgt
     6721 ccaactctgt tacacttggc tcgatagcac gcgctttatt gcgcttttcc aaatagatga
     6781 aggcaacccc gtagataatc aacatgagag caactgaaac catgttatgg aagtgggtat
     6841 caaaccaatc atcaaattta aagacaccaa gtaaaggcaa agtggcaatc aagaccttca
     6901 accatagtct ccaagtctta cgaacttcct gtttgtcctt agtcggttta aaaggattga
     6961 gcttgttaaa ataaatcacc ataactgcta aaatagcacc aagctgaatc acgacattaa
     7021 acatggacat aaaggcttca ttttgatttt ggtattggat aaactcctct gctaaaatca
     7081 agtgacctgt actggaaatc ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga
     7141 tagattttaa aatttcaata agatacatat atttctcctt atattatatt taacgcagtt
     7201 agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc
     7261 ctccaatcgc ttgacgattt ccgaaaggct ctaaccacag ctttttgttt caattggtaa
     7321 tgagtttgat aacgcataga cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg
     7381 gataaccaag tagacttgaa atactatatc tggaggtact cccatgcttt atgtgggcat
     7441 tgatgtcgct aaaaataaac acgatgttac agccttgaat gttcgaggaa aactgttctt
     7501 aaaccactca ctttttcaaa taataaagct ggttttgaac tcttagatct gtcttttcga
     7561 cagctcaacc aagactgtct catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa
     7621 tttcaacacg ataatcggca agtagaacta aaaatactgg ctagacatat tcatcgtctc
     7681 aagaaaaaac agtctgattg gaaagtacaa tacactcgtt gtcttgatat catctttcct
     7741 gagttggata aaatcgttgg aaagcattca gaatatacct accaactctt gacacgctac
     7801 cctaatcctc agaaaaggct tgaggcaaga tttgataagc tgatagaaat taagcgattg
     7861 accgcttcta aaattcagaa tatcctctca gtcgcacctc gttctatcgg aacaacatct
     7921 cctgctcgtg aattcgaaat catcgaaatc atcaaacatt acaagaggct cattgacaag
     7981 gcggaaacat gtgtcaatga cttgatggct gagttcaact cggccatcac gacggttact
     8041 gggattgggg gtcgtttagg ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt
     8101 gataatcctg ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt
     8161 cagattgatt tagctggaag aatggtcaaa cggggttccc ctcatctgcg gtgggcactc
     8221 atacaagctg ccaaagcatg cgctcgcttt tcacctgctt ttaaggccta tcttaagact
     8281 aagttagaat aaggaaaaca ttacaatgta gccatcatcc accttgcaaa aaaacttatc
     8341 cgaaccctgt tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat
     8401 ttctgaaatt aacacaggat tacctttgaa aaaatggact ttttcaaggg ctttttgccg
     8461 tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat
     8521 tgacttttct tatagtttgt ctttcttcta tcttccatta tatcatactt tttcagtcta
     8581 tggtagctct ctttaaaagg ctccgatact gccgccacct ccgcctccag agaagccacc
     8641 gccagaactt ccacttctag aagatacgga gtaggtactt gctgtatttg cgacactagc
     8701 ataatggctc atttgcgcgc ttgaatgata aaacatactg tgccagccat aagctacata
     8761 gagattgata tctggatttt caacttgaat ctgatgaacc ttcatcaaat gactaacctt
     8821 gtccgcatag ccaaataagg ttgcatagac caagagacga ttccaaacaa caatactttc
     8881 caattcagcc ttatccagtc gtgcaatctc acgtaacata ttttcaaaac tggtccagag
     8941 atagtagacc tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt
     9001 ccaataatag aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta
     9061 aagatagcca tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcaa
     9121 gatagtcaag acacccatac ccacttgcaa agccttttcc aaaccagtta aaggacgata
     9181 gtaatctggg agcccccaga aggaaactcg ttttctcact ccttcttgca tctggttcaa
     9241 tacctcttca aaagaagatt tgagttgaag ccctcttgct tgaatccgtt tttcatcaga
     9301 aactttggct ctacgataaa gactatcaga taccttgtaa tccgcaaaca aattggaaag
     9361 agtttcttct tttttacctg aaaaagctag atttaggcag tctttctcaa agcttgacaa
     9421 accatcttct tttactagcc tcaaaccaac tgcatctcct tctgaaatga tagagacatt
     9481 cccacggtct atcacatcta gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc
     9541 agctcccttg accaagggac tcacttcctc caaggaggtc gagtagactg cttctgataa
     9601 aaccataggc tctaattcca ttgggggttc atagagacga tgatttttag catatttgat
     9661 tgaaggagcg gtctttcttc tatagataaa atagaaacag atgctcaata acaaggagat
     9721 ggaaaggatc gaagggaaga tccaagtaag tagttgttta ctttgatctt tttctttaac
     9781 gatcgaatcc tctatcttat taaactcttc taaacgattc cctttcaagc cctgatccct
     9841 agcgctagca aaatcagttc gcggccagta ggcatgcaat tcaactccac gcttagccgg
     9901 aagattgtct aaacgaatag tataatcaag gttactcttt tcaaccgttc tctctctaaa
     9961 aagtttccct gtatggaaaa agagtttctc agcccccttg tctcccctta catgaaattc
    10021 aaacttttca atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc
    10081 atcataaagg aaaagtaaat tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc
    10141 ctcctgacct ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct
    10201 agtcacatct gctagttctg caccgttttt cgcggcctga atctttggat gagggtcaat
    10261 gtcaaacccg ctaggcatct taccagcacg tccaagtccc acgatttggc ccttaaagtc
    10321 ctcctcaaac tggtaaacta tcttctgtct aaactctgcc gtattgtctg catgaatata
    10381 caaatcccct tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag
    10441 gcaaaacaag cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt
    10501 atctttctta tcattatagc attttttcgt aagtaaaggc ttacttatgt tgaaaaatta
    10561 cgcatttttc gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca
    10621 tgagaaaaat atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg
    10681 ttgctcaagc cgatgaatat ttacgcatcg gtatggaagc agcatatgct ccctttaact
    10741 ggacccagga tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca
    10801 acggatacga tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa gaacctttgg
    10861 ttgttaaaac caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga
    10921 ttatcgcagg tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt
    10981 actatactag cgaaccagtt ttgcttgtca aaaaagattc tgcctacgca agtgctaaat
    11041 ctttggatga ctttaacggt gcaaaaatca cttctcaaca aggggtctac ctttataact
    11101 tgattgcaca aatcccaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc
    11161 gacaagctct tgaggctggt gtcattgatg cttatgtttc tgaacgtcca gaagcactga
    11221 ctgctgaagc tgcgaactct aagttcaaga tgattcaagt agaacctggt ttcaaaactg
    11281 gggaagaaga tacagctatc gctatcgggc ttcgtaaaaa tgacaatcgt attagccaaa
    11341 tcaatgccag cattgaaacc atttcaaaag atgaccaagt tgccttgatg gatcgtatga
    11401 tcaaggaaca acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc
    11461 aagttgctaa aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc
    11521 ttttaatctc tatcgtcgga accatcatag gtctcattat tggacttgcc attggtgtct
    11581 tccgtactgc tcctctctct gaaaacaaag tcatttacgg cctacaaaaa ctagtcggct
    11641 gggttctcaa tgtctacatt gaaattttcc gtggtacgcc aatgattgtt caatcgatgg
    11701 ttatctacta tggaactgcc caagctttcg ggatcaacct tgaccgtaca ctggctgcta
    11761 tcttcatcgt ttcaatcaat accggtgcct acatgactga aatcgtccgt ggtggtatcc
    11821 tagcagttga caagggacaa tttgaagctg cgactgctct tggtatgacc cataaccaga
    11881 ccatgcgtaa gattgtccta cctcaggtag tccgtaacat cctacctgca actggtaatg
    11941 aatttgtcat caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt
    12001 atttctcagg aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca
    12061 tcgccgtgat ttactttgtc ctcaccttca ccgtaacacg tatcctacgc tttatcgagc
    12121 gcagaatgga catggatacc tacactacag gtgctaacca aatgcaaacg gaggatttga
    12181 aataatgaca caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga
    12241 agtgctaaaa gacatttcac tcactgtcca caagggagag gtcatctcta tcatcggaag
    12301 ctctggaagc ggaaaatcga ccttcctacg ctccattaac ctacttgaaa caccaactga
    12361 tggacaaatc ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata
    12421 ccgtgaaaag ttggggatgg ttttccaatc ctttaacctc tttgaaaatc tcaatgttct
    12481 tgaaaacaca atcgtcgctc agacaactgt cctaaaacgc gaacgcacag aagctgaaaa
    12541 gattgccaaa gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagccaaacc
    12601 aaaacaactc tcaggtggtc aaaaacaacg tgtggccatc gctcgtgccc tctccatgaa
    12661 tccggacgct attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga
    12721 agtcctcaaa atcatgcagg acctggctca ggaaggcttg accatgattg tcgtaaccca
    12781 tgaaatggaa tttgcccgtg atgtctctca ccgtgttatc tttatggata agggcgtgat
    12841 cgctgaagaa ggtaaaccag aagacctctt caccaatcct aaagaagacc gaacaaaaga
    12901 gttccttcaa cgctatctca aataaaaaga aaaggctgca tcaaccgtgc agtctttttg
    12961 ctgtcctcaa aatgaaaagg cagattctct atctctacta cttgaaggtc aagaatccgc
    13021 cgttatccaa agattaatct tcaaattttt cataattttt ttcatagaaa tcaattaggc
    13081 ctagggctgt ttcaaatgaa atatttttta cttttgcacg accctgcgcc agagcaatga
    13141 tagacatttc acgcgcattc gtttctttag agatacggta gcctgtgatt ttcttatcac
    13201 gaacccagcc aacaactgat tctacttttt caaagtttga cttagccatg tttttctcct
    13261 attttcttct ttataatatt taattgtata cgtttttact acttttgtca ataaaaaaaa
    13321 catatattca acgaaaataa ttagttcaga attttcttac ttccttttta aatccgataa
    13381 tatataggtt ttgctagcct ctacaccata aatatttgct aataaaaata ctgtattatt
    13441 accctcttaa ggtgcgaaat tattcaagtt cttaaaaaat gcttctctat ttccgtaaga
    13501 tagcttattt cttcgattta agaactgaag atgatagttc taacctttag aaatccaagc
    13561 cttcactagc tcaaaaactc ctatctttct tcctcaataa atcatctgag agataggtat
    13621 tccttatgtc cttcaaattc atcactcctt tggatattga ggtgctagcc tagaagcaga
    13681 cacccgatta tctaaaccat ccttaataga gatgacaaga cagataagct cagttaatta
    13741 cttatatatc tttttaatat agtatatttg tcaacaaaaa gaaatcaaat cataccttat
    13801 actcaatgaa aatcaaagag caaactagga agctagccgc aagttgctca aaacactgtt
    13861 ttgaggttgc agatagagct aacgtggttt gaagagattt tcgaagagta ttaaagacag
    13921 tgtgactatg cttgtcaata gataggaaat caaaatgaag gtatgatatt tttttattag
    13981 tcctcagaca agcatattat aaagcgtttc attaccattt aagttaatat aagctggatc
    14041 aaaaccttcc attctacgaa tcaaacctgc ataatcatgc ttatctgcta aagcgatccc
    14101 aattaatact gggcctgttc ccttgctagc tcgtttgata tactcaaaac gtgtgatatc
    14161 atcatttggc cccaggatat catttacaaa ctcacgcaaa gctcctggac gttgtgggaa
    14221 attgaccaca aagtaatgtt tgataccatc ataaatcaag gcacgctctt ccatttctgg
    14281 catacggttg atatcattat ttcctccaga aatgatacaa caaatggttt tccccttaat
    14341 atattcagct aaaacctcta aagaggcgat actagccgct ccagcaggtt ctgcgactat
    14401 cccttgctta gagtaaaggt caatcaaggt ttcagaaatc aatccctcat cgacacctac
    14461 caaagtttta atatgttgac gagttgcttc ataggtcaac tgacctacct tttgcacagc
    14521 aatcccatca gcaaatttat caatttcctt gagttttact ggacctccag cctcaaaggc
    14581 agctttcatg gaacgcgctc cattcgcctc tactccgata acctcaatct ctggacttgt
    14641 ttccttgata taggtagaaa ccccggcaat gagaccgcca ccaccaacag gaaccaagac
    14701 agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa atctcataag caactgttcc
    14761 ttgacctgct tgaacatgag catcatcaaa aggatcaata aaggtacgat tttcagagac
    14821 tgtaaattct tgagctgctt tggctgaggc atcaaaggta tctccaacta gtttaatagt
    14881 tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg tagtaatggg
    14941 cataaagata gtagcaggaa ttttcatttc attacaagta taggctactc cctgcgcatg
    15001 atttcccgca gaagcgcaga ctaccccacg ttcacgttct tccttgctga gctgggaaat
    15061 ggcataatag gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt cttttttcaa
    15121 ataaatctta gcaccatact tctccgataa ataatgatcg taatccagtg gagtattcac
    15181 aaccacaccg ttcaagacct tgtgagcctt gattatatct tttgaactta acatataaaa
    15241 cctctttttc tataaaaaac agtcactaat gactgttttt tagttattca tctccgaaaa
    15301 cttcagtaac actttcatgg tatttatgag ccatacgaat cgaaaactct ttaggaagtt
    15361 cataacgatt tgtggaaatc caatcatata accattctac caaactttct tcactatcat
    15421 tacgatggaa gataaaatag tttaaaattt ctttatattc tacatcattc aaatccaacg
    15481 tgtctacaaa ttgactacga ggaacaaaat tagaatctaa ttttcttagt tgatctgtca
    15541 attctcccaa ttgtaaatcc aactgaaaaa atagtttttg cagttgccta tcagtttcat
    15601 cacatcctgt cttgatagaa aacaaattgg taatattcat atgatttcaa cccctaaata
    15661 agtacatcta atatcccacg aatagctgaa gctaaagttt tcgcagtcca gtcatttaaa
    15721 cccgattctt tcaatccaga tgcaataatt tgctctattt gatataaacc gccatctatc
    15781 gtctcattta ttctgcgaag aggaccttca atataggata aagcttctcc gaatctaaca
    15841 gctgatttag gtcctaatga tttaccaact atatttgtta atgtttttta tttctcaaaa
    15901 tccatttcgc tatataacga gcagatttag tcgcaccagc tctctcaaac ggagaatgaa
    15961 tttcaagacc ttcttctcta gctatttgtg ccaatttgaa gaattgttca aagttcatat
    16021 gcaacctacc atcttcaaaa ttagcatcat cataaatgtt aattacagca ttttcatcat
    16081 acgaccaatc tgctttattt tggtctgcta gcactattac cgacggtgta attacattat
    16141 acaactagaa ccaataataa cgatgcaatt tttctcataa tctttttcat aaaatcatct
    16201 ccagcgctat atatttctaa ttagttatag attttgaatg catcatcgtc gtttttacca
    16261 acgaatggca ttgctttacg caattctgca ccaacttttt caatttcaag gttagctgct
    16321 tgttcacggt aagcagtcaa ttttggacgt ccagctttat agtcatttac aaagtcattt
    16381 gcaaatttac cattttggat gtctgccaag acagccttca tattttcttt aacttgttca
    16441 gtgattacac gtggacctga tacatagtca ccgtattcag cagtgtttga aatagattga
    16501 cgcattttct tgaatccacc ttcgtagatc aagtcaacga tcaatttcat ttcgtgaaga
    16561 acttcaaagt aagccaattc tggagcgtaa cctgcttctg tcaagacttc gaaacctgct
    16621 tcgataaggg cagtcaaacc accacaaagt acagcttgtt caccaaacaa atcttcttca
    16681 gtttcttctt tgtaagttgt ttcaagaaga cctacacgag ccgctccaac acctttacac
    16741 cagtccatag caatgttttt agcatttcct gttgcatctt ggtatactgc ataaagagct
    16801 ggaacaccaa atccttcttc gtaagtacga cgtaccaagt gtcctggtcc tttaggagca
    16861 cacatgaaga catctacatc cgcaggaact ttgataaatt caaagtggat attgaaacca
    16921 tgggcaaatc caactgcgtt tccagcttcc aagtttggag cgatttctgc ttcgtacaat
    16981 tcttgttgaa tttcgtctgg cgccaagatc atgataacat cagccaactt agtagcttct
    17041 gctactgtgt aagtatcaaa tccatcttct tttgctttat caaaagattt acctggacgt
    17101 acaccgataa taacgtcacg acctgaatca cgcaagtttt gagcatgcgc atgcccttgt
    17161 gaaccataac cgataacggc gattttttta ccgtcaagtg ctgctacttt aacatctttt
    17221 tcatattcca tttgaactgt catagctttt ctctcttttc tattatttat tgccttttag
    17281 gctggtttaa taaatttaag ttggattttt aatcgcgggt aaatccagtt gcacccgttc
    17341 gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa tagggcttcg ctcttttctg
    17401 catttcccgt catctgaatg gtaatcgagc ttggcgctac gtctactact gttgcacgga
    17461 aaggttgaat aatcgctaaa atctcagctc tcttctcagc tggcgctgac atcttaacca
    17521 aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga atcacatcaa
    17581 tctgacgatt gagctgtttg atgatttgct ccacttcatc atgagaagca acatcaataa
    17641 taatagtgat acgcgataca ttcggatctt ctgttgctcc aacagagatg ctttcaatat
    17701 taacctgacg acgagatagg acacctgtaa agcgattgag gactcctgaa cgattttgta
    17761 gttttgctgt taacattcta cgcatggaac tgcaccccca acatctcatg attactctta
    17821 ccagccggta ccattggtaa cacctgttcc ttacgagaaa tatctacctc aattagcata
    17881 ggaacatcct cagtgatgac ttcaaggtct tgagccaagg tctcaggatt gtcaaactta
    17941 tagtttttaa taccataagc ctgcgccatc aattggaaat caggaagggt atcaaagacc
    18001 gactctgatg ttctgccttc atagaaggat tcctgccact ggcgaaccat tccaagtgaa
    18061 tgattgttca gcataaccac cttgattggc accttgtaaa tattcaaaat agccaactcc
    18121 tggttggtca tttggaaacc accatcccca acaaacaaga ctacttcctt atctgggtta
    18181 gcaattttag caccgattgc tgctggaatt ccaaagccca ttgttcccaa accacctgaa
    18241 gtcactaact gacgttcatt ttggtaggga taatactgag ctgtccacat ttggtgttga
    18301 ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt caccaattcg ttcaataact
    18361 gcttgcggtt gaaccacacg ctctttctta tcataagaac gaacacgatt cttgtcttta
    18421 gtgactttct caatccactt ttcagtgttg ttgtgaactg ttggttctgc tagcaacatt
    18481 tgcaaggcct tcttagcatc tccaactaca ggaatgtctg cactgataat cttgccaatc
    18541 tcagctgggt caatatcaat gtgggcaacc ttagcattct tagcgaaagt cttaggattc
    18601 cccgtcaaac ggtcatcgaa acgagaacca atactaatca taaagtccgc ttccgtcata
    18661 gcaatatttg ctgcgaatga cccgtgcatg cctcccattc caagaaagag tgggtgactc
    18721 gttgcaatcg ttccttgtcc caaaagactg gttaccactg gaatttgata gcgttctgca
    18781 aattcattta gttccgtagc agcctcagca taactaattc caccaccagc taacaagact
    18841 ggctttttag ccttggacaa ttgcttcaag attttcttga tttgcatatc attcggctca
    18901 agagtcggct gataacttgg taaattcact tctggtgaat aaatgaagtc tgtttctaaa
    18961 gcagatatgt cttttggtag gtcaattaca actggccctg gacggcctgt agttgcgata
    19021 tggacagctt ccgtaatgat acgcggaata tcagctgtct cacgaacttg gtaattgtac
    19081 ttagtgattg gcatggtaat tcccacgatg tctgcctcct gaaaggcatc cttcccaatc
    19141 cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct catggcatcc
    19201 gcaatccctg taatggcatt tgttgctcct ggtccactag tgacgacggc aacacccaac
    19261 tttccagttg atttggcata accttcagct tcatgcaaac aaccttgctc atggcgccct
    19321 agaatgtggc gaatgccttt aaaattatat atcgcatcat aaaaaggcaa aaccgcacca
    19381 ccaggataac caaagatggt atcaactcct aaatcacgaa gtgtttccaa aactaggtcc
    19441 gaccccgtct taggagattc taaactgatt ttctccatta ttcccctttc tttcctctta
    19501 aaaataactt gttactatca taccattttt tcaaaatttt tcaagataaa agaagaaatt
    19561 ttctgaattt tctattttaa cgtttattta tgaatgttat ttttgttttt attaaaaaga
    19621 taccgatttc atttactaaa aagaaaaaag aactgatttc tcagtccttc attaatctta
    19681 ttccacacta aataggtatg ggtaaacagg ttgttgacct tggtgaatct cgacttcaac
    19741 gtcttcgaat tcttctacga tttcttgagc gatttcattg gcaagttctt cgcttccgtc
    19801 ttcacctaca tagaaggtta cgatttcact gtcttcatcc aacatatgtt tcaaggtttc
    19861 agtcaatgtt tggtgcatat cagggtttga cacaagaatt tttccatcca ccatacctaa
    19921 attatcgttt tcatggattt ctaagccatc gatcgttgta tcacgcacgg ctgttgtgac
    19981 gcttccgcta acgacatcgc taagagcagc tgtcatacgc tcttggtttt cttcaatgga
    20041 cttgcttgga tcaaaggcaa gaagacttgt cataccttga ggaagagtgc gagcctctac
    20101 cactaccgct ggttgctcca aaacttctgc cgcagattga gctgccatga agatgttctt
    20161 gttgtttggc aagaagatga tgttacgggc attaacctgt tcaacagcct tgataaagtc
    20221 ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca taatccacgc cttgagaaca
    20281 gaagatatct gctagacctt taccagccac cacagcaatc aaagcatact ctttttcttc
    20341 agccgacttg ataacttgag tagcttcttt ctcaacctgt gcttcgtgtt ggttacgcat
    20401 attgtcaact tttaccttga ccaagctacc atatttgaga ccttcttgca taacaagtcc
    20461 tggatcttct gtatgaacat ggactttgac aatttcatca tcgttaacaa caaggagaga
    20521 atctccaagc tcatccaagt agttacggaa ttcatcgtag tcaaaatctt tagcataggt
    20581 tggaccttgc ttaagagcta ccatgatttc agtacagtaa ccaaacgtga tgtcctcagt
    20641 cgctacgtga ccagctacag acttatgatg ctctacattg atcatctcac tcatgttggc
    20701 aggagtcgct acaaagtcct cagatgcaat atattcgcca gtaagggctg aaaggaaacc
    20761 ttcgtagatg aagaccaatc cttgaccacc tgagtccaca acgccaactt ctttcaatac
    20821 tggaagcatg tctggtgttt tagctagagc tgttttagca ccttccaagg ctgcgcgcat
    20881 gacttcaaca gcgtcatctg tttgctcagc ttttttctta gcaccgatag cagctccacg
    20941 agaaactgtt aaaatcgttc cttcaacagg tttcatcact gccttatagg caacttccac
    21001 acctgattgg aaggccagag ccaagtcttg acctgttaac tcgtctttat ccttgatagc
    21061 ttgggaaaat ccacggaaaa gctgagacgt aatcactcct gagttcccac gcgcacccat
    21121 caaaagccct ttggcaagaa tgctcgctac ttctccaact gtagaagctg gcttgtctgc
    21181 aacttcttta gcaccatttt caatggtcat tcccatattt gtcccagtat ctccatctgg
    21241 aactggaaag acgtttaatg aattgacata ttcagcttgc ttattcaagc gagttgatgc
    21301 agcctgcacc atttcttgaa ataagctagt agtaattttt gacacggtta ttctcctaca
    21361 actttgatat tttgaatgta gacatttaca gtctgagcag taattccaag ctggttttcc
    21421 aagctaaagg caacacgctc ttgaatgttt tttgacactt cactaatctt tgttccgtag
    21481 cttaacacgg tatatacatc aactgcaata ctgccatctt cggctgcctt tacgacgaca
    21541 cctttagaat aattttcctt acctagcagg gcttggaaat tatctttgag ggcattttta
    21601 ctagccatac cgaccacacc aaaaatctca gttgctgctc cacctacgac ggttgcaatc
    21661 acttcatctg ttagttcgat ttgaccatct tttgtattaa tttttacagt catccttttt
    21721 acctcaacta gttgatactc tattttatca tatttcagcc caagtgtaaa agcagaatga
    21781 tgtatcagcg gatatttact ctatttttca aacgatgtta tacccacaat aaaagaaaaa
    21841 agaccctaag gtctcctttg cttttattat taaacgcgtt caactttacc tgatttcaaa
    21901 gcacgagctg aagcccaaac ttttttaggt ttaccatcga taagaacagt aactttttga
    21961 aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt gtgaacggtt gtttcctgat
    22021 acagtcttac gacctgtaaa gtaacatact ttagccattg tgttttcctc ctattagatc
    22081 taatatagcg gatgtgctag caccacatac cgtactatgt tatcacactt tcttgttttt
    22141 tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc aggtcttgcg tgacattttc
    22201 tgctctccac atgccattgt tgattaacag aacaccagaa ttaaaattat gtgtataaaa
    22261 atcatctcta actgcagcta agggtatagc cgtcaagtcc aaatcccaca gctcatctat
    22321 cgattttctt acaacaatat ctgaatccaa atacagtaca cgagactcgc ttacatactt
    22381 tggaataaaa tacctaaaaa aagccgcata tgaaagtccc tcaaagggga gacgataacc
    22441 tttcagaata ctactgtcaa tctgaacatt cacaatctca ctattcaaag tctctagtct
    22501 tttttccatc aattggaacc attctcgcgg aaggtcatca ttaaaaacat aaaacttaag
    22561 attataatga tgaacacaaa gagattttat tgttgtttca actttatcca tataagcatt
    22621 atctgcacct aagacaatcg cttttttctc ttctttcact ctttatctta tttcttttta
    22681 ttcccatcat attattccca tcatatgttt ctacgtaacc attattttcg cctattcgtt
    22741 cgtaaaacca taccagtgga gattttagat gaagtcccat tacggtttac aatttttaca
    22801 ttacgacacg gagttttaca aatcgatttc atttgccaaa cgtagttagt gaggcagtta
    22861 gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc caattgttgg
    22921 tactgagtca catcttctcc tctaactcta cgtctggata cttgtcagca aaccagcgga
    22981 gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg gctaagatat
    23041 tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga acggtctttt
    23101 tacccattgg gctcatgacc acttccgcat tgtattcgcc ttccatgcgg tgtttaaaga
    23161 cttcaaactg gagttgacca acagctccca gcatgtactc gcctgtttgg taattcttat
    23221 aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag gatttttgct
    23281 tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt ggcagtggtt
    23341 caaattcaaa cttggtttta ccaactgtca aggtatcccc aacttgataa gtaccggtat
    23401 cgtaaacccc gataatatca cctgcaacgg cattggtcac attctcacga ctttccgcca
    23461 taaactgagt aacattagac agtttagccc ccttaccagt acgagggaga ttaacactca
    23521 tgccgcgctc aaattcgcca gatacgatac ggacaaaggc aatacggtca cggtgacgag
    23581 ggtccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca taaggatcca
    23641 caatttcacc gtctgttttc ttgtgaccat gtggttctgg agcaaacttg aggaaggttt
    23701 caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt
    23761 ctccagccag aatagcttcc tctgaaaact cattcccggc ttcatttaaa agctcaatat
    23821 catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtcccca tcttctagac
    23881 tggcaaaacg ctcatcccct ttataaagct ctaaacgttg gttatagagg tcatacaagc
    23941 cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca atgcccaaga
    24001 tttcttccaa ttcttgtaag agatccaaag gctcacgacc gtcacggtcc agcttgttca
    24061 taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc ttggtttgag
    24121 cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc atcaaggtac
    24181 gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc
    24241 cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc ttctcgatat
    24301 ccatccaatc agatttagca aaagtccctg ttttcttccc ttttaccgta ccagcctcac
    24361 gaatttcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc gcgtccgggt
    24421 gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc ataagttctc
    24481 tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta cattggattt
    24541 taccattcct ttcaacactc cattatatcg gattttagca tttttttcaa tttctatttc
    24601 ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca gactaaaaat
    24661 catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac acacgttgcc
    24721 aatctttcaa aattaagatt ctctgaaaaa gaaactgctg cctttgcgac caccttgtct
    24781 aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt cgcacctact
    24841 acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga aggaacagac
    24901 cgtgatcgct tgtttaaaaa cgtacctgaa aaagacaact actatatcaa ggtgccagct
    24961 atcctagacg atggaggaga tgcctaatga cttttaacaa taaaactatt gaagagttgc
    25021 acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaaaca acacttgaaa
    25081 atatcaagtc tcgtgaggaa gctctcaatt catttgtcac catcgctgag gagcaagctc
    25141 ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc ctttcaggaa
    25201 ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact gctgcctcaa
    25261 aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat gcaaaaacca
    25321 agggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt ggttcaggtg
    25381 aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt cctggtgggt
    25441 catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttgtca cttggttctg
    25501 atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa
    25561 cctacggaac agtttcacgt ttcggtctca ttgcctttgg tagctcatta gaccagattg
    25621 gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt gccagcgaag
    25681 atgctaaaga ctctacttct gctcctgtcc gcatcgccga ctttacttca aaaatcggcc
    25741 aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa ggaattaacc
    25801 cagaggttaa ggaaaccatt ctaaatgccg ctaaacactt tgaaaaattg ggtgctattg
    25861 tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac atcatcgctt
    25921 catcagaagc ttcatcaaac ttgcaacgct tcgacggtat ccgttacggc tatcgcgcag
    25981 aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggt tttggtgaag
    26041 aagtgaagcg ccgtatcatg ctgggtactt tcagtctttc atcaggttac tacgatgcct
    26101 actataagaa ggctggacag gtccgtacac ttatcattca agatttcgaa aaagtcttcg
    26161 cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac ttggattctc
    26221 tcaaccatga cccagttgcc atgtacttag ccgacctatt gaccatacct gtaaacttgg
    26281 caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct gtcggactcc
    26341 aattgattgg tcccaagtac tctgaggaaa ccatttacca agctgctgct gcttttgaag
    26401 caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac taatgaactt
    26461 tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa aaatcttctc
    26521 acctacttct gcccactttg gaaatgacca aaatgccaac actaacgtga ttgactggtc
    26581 tttcccagga gttctaccag ttctcaataa aggggttgtt gatgccggta tcaaggctgc
    26641 tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga actacttcta
    26701 tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg gatataatgg
    26761 ctggattgaa gtcaaactag aagacggtac gaccaagaaa atcggtatcg aacgtgccca
    26821 cctagaggaa gacgctggta aaaacaccca tggtacagat ggctactctt atgttgacct
    26881 caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc gttcgccaga
    26941 ggaggcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg gcatttctga
    27001 cgttaagatg gaagaaggtt ctatgcgtgt ggatgccaac atctcccttc gcccttatgg
    27061 tcaagaaaaa ttcggtacca agactgaatt gaagaacctc aactccttct caaacgttcg
    27121 taaaggtctt gaatacgaag tccaacgcca ggctgaaatt cttcgctcag gtggtcaaat
    27181 ccgccaagaa acacgccgtt acgatgaagc gaataaagca accattctca tgcgtgtcaa
    27241 ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct ttgaaatttc
    27301 tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag aacgtcgtgc
    27361 gcgttatgta tctgaccttg gtttatcaga ctacgatgct agtcagttga ctgctaataa
    27421 agtcacttct gatttctttg aaaaagctgt tgctctagat ggtgatgcca aacaagtctc
    27481 taactggctc caaggggaag tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca
    27541 aatcgaattg acaccagaaa acttggttga aatgattgcc atcatcgaag acggtactat
    27601 ttcatctaag attgccaaga aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg
    27661 tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct tgatcccaat
    27721 catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt caggcaaacg
    27781 taacgccgac aaggccttta caggattcct tatgaaggca accaaaggcc aagccaaccc
    27841 acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa actagacaga
    27901 acaaaaccag ccctaaggtt ggttttttct tctctaccaa ctcccaataa ctattttggc
    27961 tttatttcca gagtatttta tggtaaaatg aagagtaata atatttatta aagaggtaaa
    28021 aacatgattg aagcaagtaa attaaaagct ggtatgacct ttgaaacagc tgacggcaaa
    28081 ttgattcgcg ttttggaagc tagtcaccac aaaccaggta aaggaaacac gatcatgcgt
    28141 atgaaattgc gtgatgtccg tactggttct acatttgaca caagctaccg tccagaggaa
    28201 aaatttgaac aagctattat cgagactgtc ccagctcaat acttgtacaa aatggatgac
    28261 acagcatact tcatgaatac agaaacttac gaccaatacg aaatccctgt agtcaatgtt
    28321 gaaaacgaat tgctttacat ccttgaaaac tctgatgtga aaatccaatt ctacggaact
    28381 gaagtgatcg gtgtcaccgt tcctactact gttgagttga cagttgctga aactcaacca
    28441 tctatcaaag gtgctactgt tacaggttct ggtaaaccag caacgatgga aactggactt
    28501 gtcgtaaacg ttccagactt catcgaagca ggacaaaaac tcgttatcaa cactgcagaa
    28561 ggaacttacg tttctcgtgc ctaatctcta gaaagaggtc attctatggg aattgaagaa
    28621 caacttggcg aaatcgttat cgccccacgt gtacttgaaa aaatcattgc tatcgctact
    28681 gcaaaggtag agggtgttca ctctttttca aacagatcag tgtctgatac cctttcaaaa
    28741 ctttcactcg gccgtggcat ttatcttaaa aacgtggacg aagaactcac agcagatatc
    28801 tatctctacc ttgagtacgg agtaaaagtt cctaaggtag cggttgctat ccagaaagct
    28861 gtcaaagatg ccgtccgtaa tatggctgat gtagaactcg ctgctatcaa tattcacgtt
    28921 gcaggtatcg tcccagataa aacaccaaaa ccagaattga aagatctatt tgacgaggac
    28981 ttcctcaatg actagtccac tattagaatc tagacgccaa ctccgtaaat gcgcttttca
    29041 agctctcatg agccttgagt tcggtacgga tgtcgaaact gcttgtcgtt tcgcctatac
    29101 tcatgatcgt gaagatacgg atgtacaact tccagccttt ttgatagacc tcgtttctgg
    29161 tgttcaagct aaaaaggaag aactagataa gcaaatcact cagcatttaa aagcaggttg
    29221 gaccattgaa cgcttaacgc tcgtggagag aaacctcctt cgcttgggag tctttgaaat
    29281 cacttcattt gacactcctc agctggttgc tgttaatgaa gctatcgagc ttgcaaagga
    29341 cttctccgat caaaaatctg cccgttttat caatggactg ctcagccagt ttgtaacaga
    29401 agaacaataa aaagaaaaag tgtttgatag atatcaaaca cttttttctt tgcctcccac
    29461 tatctaaaaa aatgataata gatataattg taaacaaaaa tccagatagg ttttgcatga
    29521 ttgagaaagt taaaaaaact atggcagaga atcgttaatc tcagattgtc ggtagaacga
    29581 taaacaaggg caaaaaagaa accaatcaga ctataatata ataaactaat tggatctctg
    29641 tgagatagta tcaaatggct aatcccaaag atgatagcag ataggataac atccaaatag
    29701 tacttggact agggaaagaa ggtattcata aaataccctc tatcaagagt ctcctcaaaa
    29761 acaggaccga tgattacagg caggacaaaa gataagatag tcgataaaaa ggttggttgt
    29821 ccatttgaaa aaagcacggt aaaatactca tcatgaatat tcctatgatt aatcaaatga
    29881 gcatagcgtg cccaaaaatt accgagaatc tgataaacca cataagttgc aaataagtag
    29941 aagacaaatg accagttcca gctctttttc tcaaagataa agagcatctt tttctttttt
    30001 aacctccaaa ttaatagaag gaaacttccc actaatccca ttgttaaaat aagagaatag
    30061 acatcagctc ctaaccctaa aatgatcgtc acatacaatc caattgtttg tggtaaatag
    30121 gtagatagta aaataataag caaaaatatt ccaaattgtc ttagtttttt tgtgtttctc
    30181 atcgtacttt tttgaaagat taccctgctc ggaagccgta cttccaagca tctatataag
    30241 aattaagtgc cccttgcctc atatagggag caaattctct ataatataac catctactat
    30301 atccatcttc ccaaacagca agaccacctg aagtttgctc caagtcctca gttgaaagaa
    30361 ctgtaaatgt atttgtacct gtcattgcaa gtaccttctt aaaatagatt gttgtaggct
    30421 cacatttata gtatatttct ttttttgtct attttatagc ccatctcctc aactggcaat
    30481 ttttcgacct gaattacatt tttccataaa aaatgagacc tttctagtct catttagtca
    30541 ttcttagtat tttctaaatc gttgatagcg ttcttccagc aactcttcta gcggtttttg
    30601 tgaaagtcta gccagctccg tttggagttc ttttttgaca ctcttaatca gttctttact
    30661 agaaagtcct atttcagaaa tcaccttatc caccacgtcc atttctaaca gttcatgcga
    30721 agtgattttc atcagttctg ctgcttccat agcgcgagta ccgtccttcc ataaaatgga
    30781 agcaaagcct tctggactga gaatggcata gatagaattt tccagcatcc agacacggtc
    30841 cgcgacagct agagccagag ccccgcctga accaccttca ccgataataa tggcgataat
    30901 aggaactttc aggtcactca tttccatgag attgcgagcg atagcttccc cttgaccacg
    30961 ttcttccgct ccgacaccag gataagcacc tgctgtattg ataaaggtca caactggacg
    31021 gccaaatttc tcagcctgtt tcatcaaccg cagtgccttt cggtagcctt ctggatgtgg
    31081 ttggccaaaa ttccgtttga ggttgtcttg caaactcttg cctttttgga taccaaccac
    31141 tgttacagct tggtctccaa gccaaccaat accaccaaca actgcaccat catcacgaaa
    31201 agaacggtca ccatgtaatt ggataaattc atcaaaaatg cctgtcgcaa agtccaaggt
    31261 tgtcaagcga ctctgctcac gcgcttctct gactattttt gcaatattca tctaggactc
    31321 cctccatgca atctgactag gctagcaatc gtatctggta agtctcttct tttgacaata
    31381 gcatccacaa agccatgttc taataggaat tctgcctttt ggaaatcctc aggcaagctt
    31441 tcacgaaccg tattttcaat cacacgacgc ccagcaaaac caaccaagct ctgtggttca
    31501 gccagaatga tatcgccttc catagcgaaa gaagctgtca caccaccagt cgttggatct
    31561 gtcaaaatgg tcaggtaaaa gagaccagca tttgaatgac gtttaaccgc cgcagagatc
    31621 ttagccatct gcatgagact catgattcct tcctgcatac gggctccacc agaggctgtg
    31681 aataggacaa ctggcaattt ttcgacagtc gcatactcaa acaaacgagt gattttttca
    31741 cctacaaccg tacccataga agccatgata aagttagaat ccataatccc aagagccaca
    31801 gtctgacctt taataagagc agttcctgtc acaacggctt catgcagacc tgttttttca
    31861 cgcatagatg ccagtttctt ttggtaacca gggaaatgca agggatcctt gctttcaatc
    31921 cctgtaaaca attctttgaa ggttcccata tcaatcgtca aagccaagcg ttcttgggca
    31981 gaaatacgaa aggtatagct acagtgcgga cagatacgtt cacttcccag atccttctga
    32041 tagatggtat gcttacagcc tggacactgg gaaaataatt catctggaac ctctggctta
    32101 gcttgaggtt tttccctaac tgaacgattg ggattgattc gaatatactt atctttttta
    32161 ctaaatagag ccattgattc cccttttcgg tttaaactct taaagtcatt ttattctttt
    32221 tcttgatatt taggtaagaa ggtttccatc aagaaggaag tatcataatc cccagcaatg
    32281 acattgcgat ctgaaatgag gtcaagctgg aaatctgcat tggtctgcac tccttcaatc
    32341 tctaattcat agagggcacg ttgcattttc atcaaggcgt caaaacgatt ttcgccgtgt
    32401 actatgattt tggcaatcat actatcataa taaggcggaa tggtataacc tggataaact
    32461 gctgaatcca cgcgcaagcc aactccgcca cttggcagat agagattagt aatcttacct
    32521 ggacttggag caaagttaaa ggctgggttt tctgcattga tacgacactc gatggcatga
    32581 ccgcgtagga caatatcttc ttgcttaaca gacaaaggct gacctgccgc aatgcaaatc
    32641 tgttccttaa cgatatcaac acctgaaaca aactctgtta ctggatgttc tacctgaaca
    32701 cgagtattca tctccatgaa atagaaattg ctacttgctt catcaagaag aaattcaatg
    32761 gttcctgcat tctcatagcc aacaaactct gccgctcgaa cagcagcagc acctatttca
    32821 tgacgcagcg tttttccgat tgcaatcgag ggactttctt ccaaaacctt ttggttattc
    32881 ctttgaagag aacaatcccg ttcacccaag tgaatcacat gtccatgctc atcacctagg
    32941 atttgaacct caatgtgccg agctggatag ataacccgtt ctatgtacat ggcaccattg
    33001 ccataattgg ccttggcctc actagaggca gtttcaaagg cagaaacgag gtcatctggt
    33061 ttttcaacct tacgaatccc tttaccacct ccacctgctg aagccttgag cataacagga
    33121 tagccaattt tttcagcaac aatcaaagct tcttcagagt tatgcacttc tccatctgaa
    33181 cctggtataa caggcacacc tgctttaatc atctgagcac gcgcattgat cttatccccc
    33241 atcatatcca taacatgacc agatggaccg ataaacttga tacctacttc ttcacacatg
    33301 gtcgcaaatt tggaattttc actgagaaat ccaaaaccag ggtgaatagc ttctgcctca
    33361 gtcaagactg cagctgatag aactgcatta atattgagat aagactctgt tgccttgcca
    33421 ggaccaatac aaactgcttc atctgccaaa agcgtatgaa gagcttcctt atcagcagtt
    33481 gaataaaccg ctaccgtcac aatccccaat tcacgtgccg cacggataat acgaaccgca
    33541 atttcaccac gattggcaat taaaattttt cgaaacatgg agaacctcct tagttcccaa
    33601 ttgcaaaagt aagggtacca ctggctgcaa gcttgccatc cacttcagcc tttgcttcaa
    33661 ccacagctat ggtgccacga cgttttacaa aagtcgctgt cataaccaat tggtcgcctg
    33721 gtacaacttg cttcttgaac ttaaccttgt ccataccagc gtaaaagacc agttttcctt
    33781 tattttcagg ttttgataac tccaacacac cggcagtttg cgccaaggct tccataatca
    33841 gaacacctgg cataactggg tattgaggaa agtggccgtt aaagaaaggc tcgttgatgg
    33901 tcacattttt gatagcaaca atggtatcct cgctcacttc caagacacgg tccactagaa
    33961 gcataggata acggtgggga agagcttctt tgattccttg aatatcgatc atttgatacg
    34021 taccaatcct ttaccaaact caaccatttc ttcgttagag acgagaattt ccgttaccac
    34081 accatcctta ggagctggga tttcattcat gactttcatg gcttcgataa ttaccaatgt
    34141 ttgacctttt ttgacactat caccaactgt aacgaaggca ggtttatctg gtccagcagc
    34201 caagtaaacc actccaacaa gtggactctc tacaagattt ccctcagtag ccacacttgc
    34261 ttcagctgga gctggaactt cttctgctac agtctctgct ggagcagatg taggagctac
    34321 tggactcggt gttgctagaa cgggtgctgg agcgacttga gttgcaactt caggcacagg
    34381 tctcgcttca ttcttgctaa actgcaactc atccgtccca tttttataag aaaattctct
    34441 caaacttgac tggtcaaatt gagtcatcaa gtctttaata tcgtttaaat tcatacttat
    34501 ctattctccc aacgtttgaa agcaagaact gcattgtggc ctccaaaacc aaaagtattt
    34561 gaaatagcgt atggaatttc tttctccaag ccttgtccat aaacgacatt agcttcgata
    34621 taatctgata cttcacttgt cccagctgtc attggtacaa agttatgacg catagcttcg
    34681 atggtgacga tagcttctac tgcacccgca gcccccagca aatgtcctgt aaaagacttg
    34741 gttgatgata caggtacttc cttaccaaga acagctacga tagcaccact ttctcctttt
    34801 tcattggcag gagttgacgt tccgtgagca ttgacatagg ctacttgctc tggagaaatc
    34861 tcagcttctt ccaaggctag tttgatggcc ttgatagctc cctgaccttc tggatgtgga
    34921 gaagtcatgt ggtaggcatc acaagtattt ccgtaaccaa ccacttcagc caggatagta
    34981 gctccacgtt tttcagcgtg ttcaagactt tctagaacca acatccctga accttcaccc
    35041 ataacaaacc cattgcgatc cttatcaaat gggatcgaag cacgagttgg atcctctgta
    35101 gtagagagag ctgttaaggc ttggaaacca gcgatggcaa aaggtgtgat agaagcttct
    35161 gttcctccca ccaacatcac atcttggaaa ccaaacttaa tagagcggaa ggcatcccca
    35221 atcgcatcat ttgatgaaga gcaggcagta ttgatagatt tacaaacacc atttgcacca
    35281 aaacgcatgg ctacattccc agaagccata tttggtaaag cttttggaag agtcattggt
    35341 ttgacacgtt tgggtccttt ttcatgaagg cgaagtacct gatcttcaat ttccttgatt
    35401 ccaccaatac cagatgcaac gataacacca aaacgatccc tattaagagc ctctacatca
    35461 agattggcat gatttacagc ctcttgggct gcatacaagg catataaaga atagttatca
    35521 aaacggttgg tatctttttt tacaaagtat ttatcgaacg gaaaatcttg gatttctgcc
    35581 gcattatgca catcaaagtc actatgatca aattttgtaa tgccaccaat gccgattttc
    35641 ccagttgcta aactattcca aaattcttct ggtgtatttc cgattggaga tgttactcca
    35701 taacctgtta ccactactcg atttagtttc attcttttca cctctagctt tcgctacata
    35761 cttaagccac catcaatggc aaccacttga ccagttagat aatcttggcc tgctaaaaat
    35821 actgtcaaat ctgcaacctg ctctgcctgc ccaaattctt tcatcggaat ctgagctagt
    35881 gtagcttcct taatcttatc tgataagata gctgtcatat cagactcaat cattcctgga
    35941 gcaatcacat tgactcgtat attccgacta gcgacctcgc gtgccacaga cttggtaaag
    36001 ccaatcaagc cagccttaga agcagcatag ttagcttgac caatattccc catcaaacca
    36061 acaacactag acatattaat gatagcacct tctctggctt tcatcatcgg tttcaagact
    36121 gattgtgtca tattaaaggc accagtcaga ttgaccttga gcactttttc aaaatctgct
    36181 tctgtcatct tgagcataag agtatcttgg gtaatccctg cattgttgac caaaacatct
    36241 actgaaccca gttctgcaat agcttgatca atcatacgct tagcgtctgc aaaatctgat
    36301 acatctcctg aaatgggaac caccttgata ccatagtttg aaaactcagc gagcaattct
    36361 tctgagattg ccccacgact gtttaagaca atgttggctc ctgcttgagc aaacttgtgg
    36421 gcgatggcaa gaccaattcc acgactcgaa cctgtaataa agatattttt atgttctagt
    36481 ttcatttttt tcctttcaaa acttctactt attttagtct atttttctaa aagtgctact
    36541 aaactcgctt gatcttccac atgagctaag tgagcagttt gatcaatttt tttaacaaaa
    36601 cctgacaaga ctttccccgg tccaatctcg ataaagttgc ttatgcctgc ttcttgcatg
    36661 accccaatac tttcatagaa acgaacgggt tccttgacct gacgcgtcaa gagctgagca
    36721 atgtcctctt tttgcatcac agcagcttct gtattgccga ctaggggaca agtaaaatct
    36781 gaaaaactta cctgagctag agtttcagct agtttctggc tagcaggctc aaggagagcg
    36841 gtgtgaaagg gacctgacac cttaagagga atcaagcgtt tggcacctgc ttcttgcaaa
    36901 agttcaaccg ctcgatcaac tgcaaccact tctccagcaa tgacgatttg tgcaggtgtg
    36961 ttatagttgg ctggagtaac cactccaagt tcagaagctt tttgacaggc ttcttcaatg
    37021 acctctactg gcgtattgag aactgctacc atcttgccag agtcagcagg agccgcttct
    37081 tccatatagg ctccacgctt agctaccaag gcaaccgcat cttcaaaatc caaggcgccg
    37141 cttgccacca aggcagagta ttctccaaga gacaaaccag caaccatatc aggctgatag
    37201 cccttttctt gcaataaacg gtagatagca accgaagtcg ctagaatggc tggttgcgta
    37261 tagcgggtct gattgagttt gtcttcttcc gtatcgatga gataacgtaa atcataaccg
    37321 agcacctgac tcgctcgatc aatcgtttct ttgacaatcg gatactgatc atagaaatcc
    37381 cgtcccatcc ctagatactg ggcaccttga ccagcaaata aaaaggctgt tttagtcatt
    37441 tcttacaact cctgcccagc gagaggcttc ttcttgaatt ttcttagcgg ctccgtaata
    37501 caaatctttt aggatttctt cagctgtttc ttctttagaa acaagccctg cgatttgacc
    37561 tgccatgaca gagccaccat ccacatcacc gtgaacaact gctttggcta gggcacctgc
    37621 tcccatttgt tcaaagattt ctaaatcagg atcttcctgc ttaaaggcat ctttttcagc
    37681 cagttcaaaa tctctagtca actgattttt aatagcacga acagcatgac caaagtgctg
    37741 agctgaaatc gtagtatcaa tatcccttgc ttttaaaatt ttctccttgt agtttggatg
    37801 ggcattcgac tcttttgcaa ctacaaaccg tgtccccacc tgtacagcct ctgcacctag
    37861 cataaagcca gccgcagcac cttcaccatc cgcaattcct cctgcagcaa taacaggaat
    37921 agatatagct gtggctacct gtcgcaccaa ggtcatggtt gttaatttac cgatatgccc
    37981 cccagcttcc attccttctg caataacagc gtctgcaccg attttttcca tgcgtttagc
    38041 taaagcgaca ctaggaacaa caggaataac gattatccca gcttcatgga aacgttccat
    38101 atacttgctt ggatttcctg ctcctgttgt gacaacttta acaccttctt caataacgag
    38161 atccacgata tcttccacaa agggagataa gagcatgatg ttgaccccaa agggtttatc
    38221 agtcaatgat ttgattttat caatattggc cttgacaact tctttcgggg catttccccc
    38281 accgataatt cctaatcctc cagccttgga aacagcccct gccaaatcac catcagcaac
    38341 ccaggccatc cctccttgga aaataggata gtcaatcttc aataattctg taatacgcgt
    38401 tttcatagtg cctccaacct tccttgctta cgtaatagtt cgatttcacc ataatttgac
    38461 agtcaaacta ttacctaaac aagagggagt gggtttctcc ctactccttc tactaatatt
    38521 ctgcttattt tgcttgctct tcaacgtaag caaccaagtc accaactgtt ttcaagtcat
    38581 tttctgcttc gatttggata tcaaaagcat cttcgatttc tgagattact tggaacaagt
    38641 ccaatgaatc tgcgtccaaa tcatcaaaag ttgattcaag tgttacttct gatgcgtctt
    38701 ttccaagttc ttcaacgata atttcttgta ctttttcaaa tactgccatg ataggactcc
    38761 tttaaaataa atagtttttt tataacaatg tgttcaccac atgattacct aaattgtaag
    38821 aatgagcgtg ccccaggtca agcctccacc gaagcctgat agaagaacag tctggctacc
    38881 atctaaaggg atgagacctt gttctacaca ctctgaaagt aaaatcggga tactggctgc
    38941 actggtattg ccatattcca tcatattggc tggaagtttg gctcggtcaa caccaatttt
    39001 tctagccatc ttatccaaaa tacggtcatt ggcttgatga agtagcagat aatccaagtc
    39061 tgtcacctct ataggagatt catcaatagt ctgcttgata gacttggcta catctcgaat
    39121 ggcaaaatca aagactgtgc gtccatccat cttcaaaaac gaatctgcac tttcttgatc
    39181 tgaaaatgga gaatgcaaac ctgaatgccc ataagttaaa cactcgctgc gacttccatc
    39241 gctattgaga ctctcagcta agaaatgctc ttgctcgcta gcttctaaca agacaccacc
    39301 agcaccatct ccaaacaaca cagctgttga tcgatccgac caatcgactg ccttagagag
    39361 ggtttcacta ccaatcacca agcctttttg aaagcgacca gaagcgataa acttttcagc
    39421 agttgaaaga gcaaatacaa atccactgca agccgcggtt aagtcaaaag caaaggcttt
    39481 attagcgcca atattagctt gaacacgagc agctgtagag ggcatcatcg aatctggagt
    39541 aatggtagct aggatgataa aatccagttc ttttcctgtt attccagctt ttgccatcag
    39601 tttcttagca acctctgtag ccaaatcact ggtagattct gttcttgaaa tatgcctttg
    39661 tcgtattccc gttcgacttg aaatccactc atcattggta tccataatct gagccaagtc
    39721 gtgatttgta accacttgct ctggcacata atgagcaacc tgacttattt ttgcaaaagc
    39781 cattatttca aatcctccaa aaattggtaa agattagtca aacctttacc catgacagca
    39841 atttcttcct cgctcatgcc atcaataatt ttttctacca tggccttgtg gaagcgttta
    39901 tgcagcctat gaatcaagcg acccttcttt gtcaaatgca gatgcaccac acgacgatcc
    39961 tgttctgacc gaactcgctc aatgtagccc ttacgctcta aattgttcaa acttgtcgta
    40021 acagttccaa gagttaccat caactctttt gacacttgac ttggagtcac gtctggagcc
    40081 ttaccgatga catcaatcgt atgcatttct ttgatggaga tatccttaaa acgactacct
    40141 ctcaagttca cttcctcaat tacaaggaca ttgttaaata tagatgttaa atattcattg
    40201 attcgttggt agtccatttt tcatatccct ccttcttcaa aaaactttta caatcaaaac
    40261 atttgacaga aagaattata tcaaaattca aagaatgatg caagtatttt ttattttcct
    40321 gtaaatttag gtcttcttct ctccgaatga gctcgcactc cttctttgaa atcctctgtt
    40381 tgagctaagg atttctgtag gttcagttct aaagtagcgt aaccctgcca gtctttaaat
    40441 tggctctccc aaaccaactt cttaatggca gcataggaat tacttgaagc acgtcttaat
    40501 tttttaagaa gctgttctct cgtcttttca agtttttcag cttcagaaac gcgataaacc
    40561 aacccccatt ctagggcttt ttctgccgtt aaagcctctc ctgtcatagc taattgagca
    40621 gcacgcgtca caccgatact gcggctcaag agatgaattc cccctgcatc tggagccaaa
    40681 ccaacaccaa caaaggcttg gataaactta gccttatccg tcgccaaaca gaaatctgcc
    40741 gcaacagcca tattcgctgc ggcacctgca acagcaccgt caacttccat taaaacaggt
    40801 ttggctattt gcttgatttt ataagaaatc gtattgacca actctgcgat ttttgtcaat
    40861 gatggaatat catcctcatc cactgcccgc ttcatctcta ccaaatctcc cccaactgag
    40921 aagacctttc cattggcatt gattaagata aaatgcacag ctggattttc ttctgccaaa
    40981 gtcagagctt ctaaaatctc ctcacacatg ggaatatgaa aaccatttgc gacctcagga
    41041 cggttcaagg taaggattgc caagtcctct tcaagctgat aaataatgtg ttccatcagg
    41101 gctccttttt attttataag cagtttatac tcttcgaaaa tctcttcaaa ccacgtcagc
    41161 ttccatctgc aacctcaaag cagtgctttg agctgacttc ggctagcttc ctagtttgct
    41221 ctttgatttt cattgagtgt taaattattt cactgtcaaa gtatatcttt tttaggagca
    41281 gaaagcaaga aaaaatcgac tgaaagtgtc tcagccgata agaaaggctc gctttaggct
    41341 agaaagcatc ttattttctt cattgaaaaa agcctttctt tctgctataa tcgtataaaa
    41401 tacttacttt aggagttctt atgaaagttg ttaaatttgg aggtagttct cttgcctctg
    41461 ctagtcaatt agaaaaagtt ttaaacatcg tcaaaagcga ttcagagcgt cgttttgtag
    41521 tcgtttctgc gcctggtaaa cgcaatgctg aagatactaa ggttacggat gccctgatta
    41581 aatactaccg cgactatgtt gcgggtaacg atattagcaa gagccaaagc tggattatcg
    41641 accgctatgc tgctatggtt agtgaattgg gactaaaacc agctgtgcta gaaaaaattt
    41701 ctaaaagcat tcacgccttg gccactcttc ctattgaaga caatgaattt ctctacgata
    41761 ctttcctagc agccggtgaa aataacaatg ccaaattgat tgctgcctac tttaaccaaa
    41821 atggtatcga tgcacgctat atgcacccta gagaagctgg gattgtggtc acaagtgaac
    41881 ctggtcacgc tcgcatcatt ccatcaagtt atgacaagat tgaagaattg acaaacacca
    41941 atgaagtcct tgtcattcct ggtttctttg gtgtcactaa ggaaaatcaa atctgtactt
    42001 tctcacgtgg aggttctgat attacaggtt ctatcattgc tgctggtgtc aaagccgacc
    42061 tctatgaaaa ctttacggac gttgatggta tctttgcagc ccaccctggt attatccacc
    42121 aaccacactc gattcctgag ttgacctacc gtgaaatgcg cgagttggcc tatgcaggct
    42181 tctcagtcct tcatgacgag gctcttcttc ctgcctaccg tggaaaaatt cctctggtta
    42241 tcaagaatac caacaaccct gaccatccag gtactcgtat cgttctaaaa cacagtaatg
    42301 atgaatttcc agttgtggga attgctggtg actcaggctt tgtcagcatt aatatgtcga
    42361 aatacctcat gaaccgtgag attggatttg gccgcaaggt tctgcaaatc ctggaagaac
    42421 ttaacatcgg ttgggaacat atgccaacag gtatcgacga tctttctatc attctccgtt
    42481 ctcgccaact aactcccatc aaggaagaag aaatcctgcg tcagttggtt caaaaggcta
    42541 aagtagatca tgcagaaatc gaacacgacc tttctatcat tatgattgtt ggtgaaaaaa
    42601 tgaagagcca catcggagtg actgctactg cgacacgcgc tctatctgaa aacaaaatca
    42661 acatccagat gatgtctcaa ggttctagtg aagtttctat tatgtttgtt gtcaataaag
    42721 accaagagaa agcagcaatt aaagccctct acaatgcctt ttttggagaa agtaaggaag
    42781 actaagcatg gcccaatcac ttaacaaaac agtactcctc agtacgacag gcacttccta
    42841 cctctctatc gctgggaaag ttgggaaatt ccttgtcgga gatcaggctt tggaatttta
    42901 cccagatgtc aatgtcgaac aatttatcca gattccttgg agccatatca atcagattgg
    42961 agccaatgtc actggacgca aaatcagccg ccacttcgaa gtctttacag acaaaggaaa
    43021 attcctcttt gcttcaaaag actcaggtgc cattctcaaa attgcacgcg aaaaactagg
    43081 caatgacaag gtcgtcaaac ttccgaccct gattcagaca attagccaaa aatttaaaaa
    43141 tctatttgca aaaaagtaga aactttagta taatcatagc aacggataag taggttatct
    43201 tcttctttca gaaagtctgc gggtactgcg agcagatagg agggataggt gaaattctac
    43261 cgttagtaac aattacatac acaatcaagt gcacacctgt gaagttggat ggaaccgtgg
    43321 ccctgccact ccaacgtttt gtcaggcgtg cttttttcat aaaggagttc ttatgttaga
    43381 tatcaaacgt attcgtacag attttgaagc tgtcgcagaa aaattagcta cacgtggtgt
    43441 agatgctgct gtcttgaatg aaatgaaaga aatcgatgct aaacgtcgta acatcttggt
    43501 caaggttgaa actctcaaag cagaacgtaa cacagtttct gctgagattg cccaagctaa
    43561 gcgcaacaag gaaaatacag atgacaagat tgctgccatg caaaatctat ctgctgaggt
    43621 taaagccttg gatgctgaat tggcagaaat cgatgctaaa ttgacagaat ttacaacgac
    43681 tcttccaaat atcccagctg acagcgttcc tgttggggct gacgaagacg acaatgtgga
    43741 agttcgccgt tggggtactc cacgcgagtt tgacttcgaa cctaaagctc actgggatct
    43801 cggtgaagac cttggtattc ttgactggga acgcggtggt aaggtaacag gcgctcgctt
    43861 cctcttctat aaaggcctcg gtgctcgttt ggaacgtgct atctacaact ttatgttgga
    43921 tgaacatgga aaagaaggct atactgaagt catcacacct tacatagtca accatgattc
    43981 tatgtttggt actggtcagt atccaaaatt taaggaagat acttttgaac tcagcgatac
    44041 caactttgtc ttgattccaa ctgctgaagt tcctctgaca aactactacc gtgatgaaat
    44101 cttagacggc aaagatcttc caatctactt cactgccatg agtccgtcat tccgttctga
    44161 ggctggttct gccggtcgtg atacgcgtgg cttgatccgt ttgcaccaat tccacaaggt
    44221 tgaaatggtc aaatttgcca aaccagaaga atcttacgaa gaattggaaa aaatgacagc
    44281 caacgctgaa aacattcttc aaaaactcaa ccttccatac cgtgtcgttg ctctctctac
    44341 tggagatatg ggcttctcag ctgcgaagac ttacgacttg gaagtatgga ttccagcaca
    44401 aaacaattac cgtgaaatct caagctgttc aaacacagaa gatttccaag cccgtcgtgc
    44461 ccaaatccgt taccgtgatg aagcagatgg caaggtgaaa ctccttcata ccttgaacgg
    44521 ttctggactt gcagttggac gtacagtggc tgcaattctt gaaaattacc aaaatgaaga
    44581 tggttctgtg accatcccag aagcacttcg tccatacatg ggtggagctg aagtcatcaa
    44641 accataaaaa ataaggttta gctatttcta gctagacctt ttttcgtaac caaatcagat
    44701 aagcacctag tacaaagaat aaaatagtta ggcatataat ggtttcagcc aataccaggt
    44761 aatccagaaa tggaagtttc aaaattccct gagccatctt gagcgaggtc gctgtgataa
    44821 tggttgggaa ggtgagggct gagaaggctg gttgaaaacc ttgttttaaa atgttgggca
    44881 gacgagttaa aacaaagaaa aagaaggatt gagaagccaa aatcatgaca atcaagaccc
    44941 aagtcggcag gctggttcct cctactcgaa ctagagaagc caagagtaga gagaaaggag
    45001 cacagtagat tccttcttgt ccaagcaagg ctagtgggag tggatgtttc tttaaatcgc
    45061 tataaataag gggatagaga tagaaggtca agagaaaacc aaaactcaag gtcgcatagg
    45121 ccatttcgat aatacctacc agaggatagg tcaaggcagc cactgctatc cccacataga
    45181 gaaccgtcca acttggagtg gcatgaaccc tccgccctgg acaagcaaac ttgatggtaa
    45241 aaccagcaat caaggtcaaa tccaagagaa atgaaaacca ccaaatccct tgtgctacca
    45301 aaggaagata agagaatacg cgaaagacat aggtcgataa aatcatccca gccataggaa
    45361 aggttgccat tcctgacaaa agagggggct tggtcaattc ttgcttggtt tctttccaat
    45421 taaagagatg cagaattaga aagtaaatcc ataaaaccaa accagtcaga ctaaaaagat
    45481 gggatagaac tggcaacgta tctaaaataa gatttccagc tcctgccaaa cctagcaaac
    45541 aacctgaaaa tactaagggg agttttttca tcctaacctc caataatcat gttagtttca
    45601 gtataacata aaagcgctta aatgaggatt taaaaaaacg aagtccgatt atttcagact
    45661 tcattttact cagatatgaa ttaggcataa ggttgcaatt ctggattaat tggtgtatta
    45721 gctaagttgt tggcatagtt acagaggatt gctaggctga caccaaaaac cacatccaag
    45781 gcattttgtt gagtgtagcc agcttctaaa aactcagaca aggcttcatc tcctacacga
    45841 cccttggtat tgataactgc caaggtaaac ttagctaggg tatccaattt aggatctgtt
    45901 tcaattggag tacgattgcg aagagcttga atcaagtcat cattcatctg gatttgtttg
    45961 atggaaaagg ctgtgtgacc tgcgacacag aaggcacaac cattggtcac ggctgccgtg
    46021 atttgcacca cttcacgctc aacgggtgtc aggctgttgc gacggtggat agatgagaca
    46081 atttggtagg cttctaaaac agtcggggca ttggccaaga gaccgattag gttgggaata
    46141 tagccattgt tgtctttttc tactgtttca agaatttctt tcacttctgc tggtgctgac
    46201 tctactgtat ggatagtaaa tgttgtcata agatacctct tttcttatta ttgacactaa
    46261 tattattgga aaatcttata aaatcctgat tcctaagttt atctaagata aagctttatt
    46321 ctctcataag attttcgttg ttatattagt ttatcacact tccaatcact tgcataatat
    46381 atattatata tcaggctgat aaaaattatt tataggcaaa aaaatcacac gagctgtgtg
    46441 attccattat ttgtcaaaat actttttagt ttcagcaata acgactggcg acaagaccaa
    46501 gagggcaatc aagtttggca gagccatcaa ggcgttaacg atatctgcga taatccagac
    46561 catatccaac tcgataaatc ctcctaacaa gaccatgagc acaaaaacca cacggtagag
    46621 ccagataaag cgaaccccaa agaggaactc aaaacagcgt tctccgtaat agttccaacc
    46681 tagaatcgtt gtaaaggcaa aaagtacaag gaagatggtc aagagagcag gcccaaagtg
    46741 tgaaaagact gttgagaaag ctgactgagt caaggcaacc ccattcaagt caccgctcca
    46801 aactccagtt accaagatgg tcaaaccagt tagagtacaa atgatgaggg tatcaataaa
    46861 ggttcctgtc atggaaatca aaccttgctc tactggttca tttgtcttgg cagctgcagc
    46921 tgcaatagga gcagaaccca gaccagattc gtttgagaac acaccacgcg ccacaccatt
    46981 ttgaatagcc atccgaacgc tagcaccagc aaatccacct accgcagcaa ggggactaaa
    47041 agctgaggta aagactaaag cgattgtgcc agggattttt ccgatattaa agaaaataac
    47101 tgtaagagtt cctaagatat aaatgagggc cataaaagga acaacagtag ttgaaacctt
    47161 agaaatagac ttgagtccac caaagactgc aatcgctaca aagacagaca agacgagaga
    47221 tgtgatggct ggcgaaatcg tcgttgtatt ttggatagat tctgtaatcg agttgacttg
    47281 ggtgaaggtt ccgattccca agagagcaac caatactcct gctactgcaa acaaaacagc
    47341 aagtggtcgc cacttttctc ccatccctag aaggatatag tgcatgggac ctcccgctac
    47401 tgcaccatgg tcgtccttgg tgcggtattt gatggccaag agtccttccg catacttggt
    47461 agccattcca aagaaagccg ccatccacat ccaaaataga gctcctggtc caccaacctt
    47521 gatagccgtc gcaactccta tgatatttcc tgttccaaca gttgatgcca aggctgtaca
    47581 cagagctgca aaactggata catcaccatg tcccttatcc tggataaaaa taagctgaaa
    47641 ggccttgggt agacgcaaaa cctgcaagag tcctagccgc atggttaggt aaatccctgt
    47701 tccgaccaat aaaatcaaga ggggcggtcc ccaagcaaaa gcatcgattg atttaagcaa
    47761 ttctaacatt tccttctcct atcgtttcaa ccccaaaaga aagagcacat gcaagataca
    47821 tgtactctgg aatgcttaga taaatgctaa aaagcggtct atcctagctc tgtcctttta
    47881 cctgagagtt tgagcagttg cctgccttgc cccttcggtg cctttacggt ctctccagag
    47941 ttccgtccat ttacagtcat ggaaaatcaa acgattcccc acttctatta aacttcattc
    48001 ggtgttggta tttaattgat tctaatttta caaaaaatgt tggcttttgt caatgtgttt
    48061 attagtaaaa attagttcaa cagtttttac tttataaagt ccagaatact gctatccttt
    48121 aaaagtgaca atagtcgcac cactgcctcc agcattttgt ggggcatagc cgaaactctt
    48181 gacatgtttg tttctttgca agtatttggt aactccttca cggatgactc ctgttccgat
    48241 accatggatg atatcaactt gagccatatt gttaagcaag gcttggtcga tgaaggtatc
    48301 tagctcattc atggcttctt catagcgctt gcctcgaaga tccagtctag cttgaggtcc
    48361 tcgcccagaa gttcgtttca caacattgac ctgtttcttc ttgactggtt tttcttgctg
    48421 ggcttgaaca agatcaaact ctttctcttc caaggtcatc ttaatcaagc caacttgggc
    48481 ttcccagcgg ccgtccttga gttgactggt caaggtacca cgctgaccat aactgagaac
    48541 cacgatatca tctcccacct ttggagctcg ttttttcttg gccttttgaa ggaccttgtt
    48601 tttagacaag tccacttttt caggagccaa ttttttcaac ttggccttgg cttcaatgat
    48661 ttcgtggggc ttgagttggg atttactgtg gagatttttg agaatctggt cactttcact
    48721 tagggccata tccacaatct cagcagcctg ttcacgcgcc ttgttaagct cggtttcctt
    48781 ttcacgatta agctcgttgt agagtttttt tagagcacgg ttcatcttga gattttcttg
    48841 ctccacctca cggatattgt ccaagcgttt gcggctttcc agcgtctgct cttctaattg
    48901 ctcaatgata cgattgacgt cattgtcctg atcaatctgc tgactggcat ctcctacgat
    48961 aacttcagat aggcctagac gtttggcaat ttcaaaggca ttacttcggc caggaacacc
    49021 ctgcataaag cgataggtcg ggcgaagagt tgcagtatca aactccatac tggcattttg
    49081 cacaaaggct gtctcaatac cgtaggcctt gagttctgga tagtgggtcg tcgccatggt
    49141 cttgatttga cgcaggcgaa ggtcctccag aatagccatg gcaagggctg ctccctcttg
    49201 gggatcagta ccagccccca actcatccaa aagtaagagt gaatgttggt tgaccttgcc
    49261 aagaatatcc acgatattgg tcatatggct agagaaggta gacaagctct gctcaataga
    49321 ctgctcatct ccaatatcag caaagatttc ttcaaaaata ccaacacgac ttcccttgtc
    49381 tgctaaaatc ggcaatcctg actgggccat gacctgtgtc aagcccagag ttttgagcat
    49441 gatggtcttc ccacctgtat tgggacctgt aatgacaata gctgttaaat cttgaccaaa
    49501 atagacatca tttgcgacgg catttttgac caaaggatgg cagacatgga gcagttgaat
    49561 ctcttgattt tctgacagct gaggcacgac tgcttgtctt tcttggataa atcgaacctt
    49621 ggcacgaatc aagtccagat gaccgataat ccaagcgtca ttagcaatct cagccgcatg
    49681 agggcggaca cgctcagaaa tttcttggag aatgcgaagc atttcatagc gctcatctgc
    49741 tcgcagacta gcaatttctt cgctcagttt gactacctca cgtggttcga tatagacggt
    49801 gtttccacta gcagaaatat catgaacgac acctgcaatc ttattgcggt aggtgttttt
    49861 gactggtaaa acctgacggc catttctgct agcaacaatt ccttctgtca acatctgcgc
    49921 tttttgcttg agcaagtctt gtaaaacatc gcgtacctga ctctcgctat catgtatttt
    49981 tcgacggatt cgcgccaatt cttcactggc aaaattttca atgaaacccg catcattaaa
    50041 ggcctgaaga tttccttgta attgcggaaa atcatgtaat ttctcaaacc aaagggctaa
    50101 ttcttccaag ctgacatttt ccagattggc gtaaaaactt tgaagttctc ggctggcaag
    50161 aagcacgcgt ttcaagagta ggaactcctc gatattgaga tccgctccca tctccaacct
    50221 cttgcagact cctgcaattt ccttagttga gagaatagta aaatgcggtt gctcgacgaa
    50281 aagagcctgc atttccttca tctcagcaaa agcctgtttg attttatctg ctttggcagt
    50341 cggagccagt tgtctcaatt gctccaagcc ctgctcggtc aacaaatgag gctcaaacaa
    50401 ggccttgacc ttatcgaact ctaatgtttc taatattttc ttattcatct ttatttcctt
    50461 gtctttgaat gtctaggtgt ggtagctttt tacattctga tagattcgag tcaaatctgt
    50521 aaacaaaggg ctaggaaaac tcctgccctt tttatccgat taaatttgtc acccagattt
    50581 gtttgagcca actggttgtt atcggtatgc tctggatgat gtgttttgcg acgatactct
    50641 tttcaagagg attttgtata actgccatgg ggatggtcgc caagattgtc aaggccattt
    50701 gcaagacaaa taaggtcacc aacatggaca agatacctgc tgaaacttgg aacaacttac
    50761 cacccagttt tttgctagga atcaagtgta agagaagacc aagcaaacga ccaatgctat
    50821 agacaatccc aaatacaagc aagtagccga tgcctgcata aaagacctta tccagctgaa
    50881 agagttgatc cgatgggaaa aagaaagtcc cctgaccttc ctgcgaattt gcataaggga
    50941 gcaataaatg gaattgctct ccaagcccct tataaaactg gccagccata aaagccgatg
    51001 ccatggctga aatcaggtaa taaacctgta agagcaggcc tctccgatag ccgatataaa
    51061 atccccaaac caagaccaat agaagaagga atgaaatcat aaggaatcct caatcttgct
    51121 ctgttcttgc ttacaagtca caagcttgtg acggagttct tctagctctt gctccttatc
    51181 gtcaaattca atctcacggc tgagctgagt tgataaacag ttgactgcca acaaaagagc
    51241 gattgtttca tcatctgcgc taggcatttg ttctttaatt gcttggtatt tttctgtcgc
    51301 aaccttagcg atttcctcca taaaaaggtt atcatgttcg cttgtcaagg ttaacgattt
    51361 tttcccgaat gtaaatttga atcgatttag atttgccata aaattcacct cacgatatta
    51421 taccaaaatt cgctaatttt gtcagttttt acaaatttta ctgcttttgt ggtacaatag
    51481 aaactatggc aagtatcaca ctcacaccaa gcgaaaagga tattcaggct tttcttgaac
    51541 actatcaaac cagtctggct cctagcaaga atccctatat ccgctacttt ttgaaactac
    51601 ctcaagcaac ggtttctatc tatacttctg gaaaaatctt gcttcagggt gaaggggctg
    51661 aaaaatacgc cagtttcttt ggctatcaag ctgtagagca aaccagcgga caaaatcttc
    51721 ctttaattgg gacagatgag gtgggaaatg gttcctactt tggtgggctt gcagttgtgg
    51781 ctgcctttgt cacacctgac cagcacgact ttttacgaaa actcggtgtg ggggattcta
    51841 agactctgac cgaccaaaag atccgtcaga ttgctcctat tctcaaggaa aaaattcagc
    51901 accaggtact ccttctctca cccagcaagt acaacgaggt catcggagac cgctacaatg
    51961 ctgtttcggt taaggttgcc ctccataatc aggctatcta tctcctcctt caaaaaggtg
    52021 ttcagcctga gaaaattgtg attgatgcct ttaccagtgc taaaaattat gacaagtact
    52081 tggcacaaga ggccaatcgt ttcagcaatc ctatcagctt agaagaaaag gctgagggca
    52141 aatacttggc tgtcgcagtt tcttctgtca ttgcgcgtga tctctttctg gaaaatcttg
    52201 aaaatctggg acgagaactg ggttatcagc ttccaagtgg agctggaacg gcttctgaca
    52261 aggtggctag ccagattttg caagcctatg gtatgcaggg actcaatttc tgcgccaaat
    52321 tgcactttaa aaacactgaa aaagcgaaaa aacgcttaga aaggtaagtt atgaattcat
    52381 ttaaaaattt cttaaaagag tggggactgt tcctcctaat tctgtcatta ctagctttga
    52441 gccgtatctt tttttggagc aatgttcgcg tagaaggaca ttccatggat ccgaccctag
    52501 cggatggcga aattctcttc gttgtaaaac accttcctat tgaccgtttt gatatcgtgg
    52561 tggcccatga ggaagatggc aataaggaca tcgtcaagcg cgtgattgga atgcctggcg
    52621 acaccattcg ttacgaaaat gataaactct acatcaatga caaagaaacg gacgagcctt
    52681 atctagcaga ctatatcaaa cgcttcaagg atgacaaact ccaaagcact tactcaggca
    52741 agggctttga aggaaataaa ggaactttct ttagaagtat cgctcaaaaa gcccaagcct
    52801 tcacagttga tgtcaactac aacaccaact ttagctttac tgttccagaa ggagaatacc
    52861 ttctcctcgg agatgaccgc ttggtttcga gcgacagccg ccacgtaggt accttcaaag
    52921 caaaagatat cacaggggaa gctaaattcc gcttctggcc aatcacccgt atcggaacat
    52981 tttaagaaac ctaagaggcc gagaatcacc aatctcagcc tcttcttcta tcgtgagaaa
    53041 atgattggta actatctaaa cttaccagaa cagaaacacc tcaactctca cctattcatg
    53101 caaaggaatt ttatggaagt ttatttttca ggaaccattg aacggattat ttttgaaaat
    53161 cccagcaatt tttatcgcat cctcctccta gaaatcgacg atacggacgc agaggatttt
    53221 gatgattttg aaatcattgt cacaggaacc atggctgatg taattgaggg cgaagactat
    53281 actttttggg ggcaaattgt ccagcactcc aagtatggag aacaactgca aatcagtcgt
    53341 tatgatcgcg caaaaccaac tagtaagggc ttggtcaagt acttttcaag tagccatttc
    53401 aaggggattg gtctcaagac agctcagaaa atcgtggata cctatggcga aaataccatt
    53461 gacgaaattt tgcaacaccc agaaaagtta gaaggcatcg caggactctc tgccaaaaat
    53521 cgcgaggctt tcgtctccac tctccgtctc aactacggaa cggagatggt tttgtccaaa
    53581 ctagccaact acggcattcc caacaaacta gcctttcaga ttcaagactt ttacaaggaa
    53641 gaaacccttg atgtggttga aaattatccc taccagctgg ttgaggatat caagggtttg
    53701 ggctttacca ttgctgacca actagctgag gaactaggca tcgaaagtca ggctcctgaa
    53761 cgcttccgcg ccggtctagt tcacagtctt tttcaggcct gtatggaaac aggggacacc
    53821 tatgttgaag cacgggattt gctggaacaa acccttactc tccttgagtc ttcccgtccc
    53881 gtggaactag accccagcca agttgcccaa gagctctcct acctgatcga agaagacaag
    53941 gttcagcaga ttgataccaa gatctttgac aacagcctct ttttcgctga ggaaggcatc
    54001 cgcagtcact tggttcgtat ccttgaaaaa ggaaaacaga aaagtcatga tttaaaaacc
    54061 attcaaaaac atatcactac tatcgagaaa gagcttggaa ttgagtatga taacattcaa
    54121 aaacaggcta tctgtgatgc tatccagaat aaggtcttta tcctgacagg tggacctggt
    54181 actggtaaga caactgttat caatgggatc atcgctgttt acgccctgtt agagggactt
    54241 gacctcagga agaaaagcaa cctgcccatt cttcttgctg ctccaactgg tcgagctgct
    54301 cgtcgcatga atgaattgac aggtttgcct agcgcgacca tacaccgcca cttgggaatg
    54361 acaggtgacg atgataccag tcatctggaa gattacctag atgctgactt tatcatcgtg
    54421 gatgaattct ctatggtgga tacttggctg gccaatcaac tcttctccaa tatctcttct
    54481 aacagtaaga tcctcatcgt aggtgacagt gatcagctac cttctgtcag tcctggacag
    54541 gttctagcgg atctgcttca tattcctttg attcctcaga ctcgcttgga aaaaatttat
    54601 cgacaaagcg aagaatcaac catcgtcacc ctagctagtc agattcgaca gggcatcttg
    54661 ccagctgatt tcacccaaaa aaaagctgac cgttcctact ttgaaattgc tagtggccat
    54721 attcctgcca ccattgaaaa aatcttaggt gccgccctca gaaatggtat tcctgcccgt
    54781 gatatccaag ttctggctcc tatgtaccga gggacggcag ggattgatgc tatcaatcag
    54841 ctcatgcaag acctgctcaa tcccccacaa aaagatcaac tcagttttga agctcctcag
    54901 tgccactatc gtaagggaga caaggtcatt catttggtta acgatgctga aatcaatgtc
    54961 tttaatgggg atttaggagc tatcacagac ctgattcctg gtaaatacac cgaatcgaaa
    55021 caagacgaga ttgtcattga ttttgatggt aatgaagtct cttacccccg taacgaatgg
    55081 tacaagattc gcttggccta tgccatgagt attcataagt ctcagggaag tgagttccca
    55141 gttgtcatcc taccgattac tagtgctagc cgacgtatgc tggagcgaaa tctcatctac
    55201 acagccatta cacgtgccaa aagcaaactc atcttactag gcgaattaca agccttcgac
    55261 tatgctaccc aacacatcgg aactgcccga aaaacctatc tgattgaacg cttcagtgat
    55321 ctactggaga atgttgaaga aaagcaacaa gctgtctctg aaacagtcac atcaagtgcc
    55381 tctgaacaat cctacatcct aaccgaagaa aactgggaca gcattccagc catgattggg
    55441 attacagaca cagacctcaa agagattttt ggaaaatagt gcatcagaaa aaccaccaat
    55501 tcaggtgggt tttctgttta ttaagattat tttactgttg ctgtgcttgt aatcaattca
    55561 acagcttttt tgatagtgat atcatgtttc aacatgtcag ctgaaagcaa gttttgaact
    55621 tgtgcaactt ccatgttgta gtctgctgcc aattgctcaa cttctttttg gatttcttct
    55681 tctgaagcat caaatccttc agctttggca actgcttcga taacaaggtt agtcttagta
    55741 cgtgactcag cttctgcttg gtattggttg tgaaggtctt cttgagtagt tccagtgatt
    55801 tggaagtaca tgtcagggtt gatcccttga cgttgcaagt tcccaaggaa ttcatttact
    55861 gaacggtgaa cttcttcgtg gatcatttct tctggaagtt ctacgatttc agcattttct
    55921 acagctgtat caattgctgc accttcaact gcatctttgt aagcttcttc tttagcagta
    55981 gccaattctt tgcggtattt ttctttcaag tcagcaagtg tttcaacttc ttcatcaatg
    56041 tcttttgcaa gttcatcgtc aagagctgga acttctttag cttttacttc gtggatagtt
    56101 gtcacgaatt tagcttcttt acctgcaagg tcttctgctt ggtagtcttc tgggaatgtt
    56161 acgataacat caacggtttc gccagctgag tgacctacca attggtcttc gaaaccaggg
    56221 atgaattgac ctgaaccaag tccaagtgag aagttttcac cttttccacc gtcaaattca
    56281 acaccgtcga tagaaccaac gaagtcgatc acaacagtgt cgccgttttc agcagcagct
    56341 tccttgataa ccaattcagc cagattgttg cgttcgcgtt cgatacgctc ttcaacatca
    56401 gcgtcagtta cttctttttc tacatcaact gatacttcaa ggtttttgta gtcacccaat
    56461 tttacttcag gttttgtaac gacttcagca gtgataaccc agtcttgacc tttttccatt
    56521 gaagttacgt caatttttgg ttgggcaacc acttcaagac cagcttcttt tacagctgct
    56581 tcataagcgt ttggcaaaag agcgttcata acgtcttggt aaagtgattc ttcaccaaat
    56641 tttttatcga agataggacg tggaaggtga cctttacgga aacctggaac attaagagat
    56701 ttcttcactg acttgaagac acggtccaat tctggtttga tttggtcttg agagatagtg
    56761 aaagtcaaga caccacggtt tgtttctttg ttttcaaatg atacagacat tctgtcattt
    56821 ctccttaaaa ttttttaaat acagtctatt ataacatttt ctataaataa aatctagact
    56881 aatgcagcca attatagaca acaagccttt ttcctaacta aaacactcat aaagtataga
    56941 caattttaga ctactttgga tatcttttgg ttagtcattt tccaaaacta atttatctaa
    57001 tttttcagtt atataataga ttgaaactag aatagtacat ttctacttct aaaacatttt
    57061 tagaaatcga tttgactgtc ctgatcgatt tgtcctgttc ttgtttcatt ttactatata
    57121 gatcgcattc gaaagaattc gttccaaaat tgcttggttc gttcttctct tggacgacta
    57181 aagaattgat gggcattatt tttttcaaca attttcccac tgtccataaa aataacatga
    57241 tgggctacat ctctagcaag acctatctca taaagctgat caaaaactca atctgaggag
    57301 aaaatccaat aaggctttcc ataataaagg acatcctatc aagatttttg aacacccgat
    57361 aggctgcctt tttccgattt tgaagacttt ttgtccagct tcttttacct tataaataac
    57421 aacaaaaatc aaagacaagc tagaaagatt accgcagata actcaaacag tgttttgagg
    57481 ttgcagataa gactgacgga gtcagctcaa agcactgctt tgaggttgta gatagaactg
    57541 acgaagtcag ctcaaaatac tgttttgagg ttgcagatgg atgctaacct gatttgaaga
    57601 gactttcgaa aaagattaaa tatactctac aatttgctca atcaattctt ggtcatctaa
    57661 acctgtaact tgtataacaa catctttgac tgattgttta gccaacaatt cacctaatcg
    57721 aatactttct tcatcattta catcgcgata gtcaaaggca tagccaactg ttttaagtag
    57781 gtttttatat gacaaactga gttctttcaa ttcacgtatc ggccggatga atcgttcatt
    57841 atagcctaat tttcggattg gagtacgagc tacgcgacta acctcgtcca ctatgaaagg
    57901 gttttcaaat cgttctataa tgactttgtg ataattctcc aattcttttt tatcaaagtt
    57961 ccatttggca atcaagagac tccgaatttc agctaataca gattcaatcc gagatttgat
    58021 attaggattt tgaagagctt ccaaaattgt cttggcacca taatgcgcac caatgtaagc
    58081 tgaagttgca tgtccagaat tgactgaaaa aagttttcgc tcaataaagg gttctaaatc
    58141 ttcttcataa tgcacatctt ctagacgtaa atctggattt ttaagacgct tggtttccac
    58201 gacccattca ttaaagggct cgaccacaac aaaaagggaa tcttcgtgac tttgtgctgg
    58261 aacaatcctg tctactgcag catttggaaa acctatgtag ttatcagcaa atgtcaaacc
    58321 ttccggactt aaatatttct tgacttcttg ataaagaaat tgagacccgc caatcatatt
    58381 ttcacaggcc ataacatcca atgcctgtgt atttcctgca actcggcgag cttcgattcc
    58441 tttggctaga agttcggcga taaaagggag tatattaggt ccgattgcag tagtaataat
    58501 atccgtcctt tgaatcgctt caatgacttg ctcaggatgt tctttgctat taattccagc
    58561 cacattagtt acttctatac gagactgtcc tttctgtgca atttcaattt catacttgcc
    58621 cttttcattt agagcatgaa ttatctgatt attgacatcc acaaaatcaa tatggaaacc
    58681 atttttaaat agaatttcac ctataaaacc acgaccgata ttaccggcac caaaatgaac
    58741 agaatgtttc attcaatttc tccttttcct atttgaggga catatatact agatgacaaa
    58801 tgacgaaatt caattattca acagcatcaa ataagcgcaa tacttcctct tttgactgag
    58861 catctgctag tttaagaaca ttatccacat ctgcacagaa gatagaaatt ttctgaataa
    58921 tttctaagtg ttcattacca ataccagcaa tgccaaaaag aaccgttgcc acttgagggt
    58981 tagatacatt cccaaaatca acccctctag ggacttgaac gactgtaata ccagacttga
    59041 ggacatcctt ttttgctgca tctgttccat gcggtatggc gataaagtta cccatgtaaa
    59101 cagatagctc tttatctcgc tcaatcatgg cttcaatata gtcttcatta acatatccac
    59161 cctcataaag aacttgccca caataacaaa tagcttcctc cttgttagaa aattgtttat
    59221 taagcttaat caaatgtttt tcaagtttca tattagttct ccaatttctt aattttttcg
    59281 ttaaaaatag tatttagcat ctgataaata atggattgat ttcccgtctt gtaaatctct
    59341 gtataaagat gattttcaat aatcgactga ctaatagctg tcattaaatc tctagcttcc
    59401 tcgctagctt ctttagacat tagcattagc agacaccttt tgacctcttc ttcctctcgt
    59461 ttcattgaca atgcggagat aggtagtttg agttcaaaca tagtaaaact atttgttgtt
    59521 actttgctag actgactatg taaaagcacc agaccagtat taggaatagc cataggacta
    59581 ttctggaagt gagataacaa ttttcttgtt aggtaatctc tgtcactcac attcttctga
    59641 tattggatga tttgttctac cgtgtgctca aatgattgat tattctccaa ttgaaccaac
    59701 tcaaattgac tcaaaagctg actactagat attaaataat cttgcaagtc ataacttttc
    59761 tctggagcga tagcatcacg cgcgacaatt gtacgatgtg cctgtacata ctgaagtcgt
    59821 tcctgtaatt caagcaattc tttgacggtt ggaaaactag aaattacatc gatttcctga
    59881 ttagtcagcg gcttggtaga taaaatataa tcatactgac tgagatcaat actgtggtaa
    59941 tctactagag actgaatatc tatcaactct acaaaaggag caacactctt aattttactg
    60001 actaataaat ctctagtgac ccgacgttca tccgttaaaa gcaaaacacg gactggataa
    60061 atctctggac tacggcctaa gctagagata aaatgtaggg caatcatgcc atactcatac
    60121 tctgtatgaa gatatttcgg aaaaatatca ttcactaaaa gactgatgac tgtataaaga
    60181 aatttattcc tttcaactaa aatctggaca gattctggca aattttcacc ctgaaaaagg
    60241 atagggacgc ctaaactgag ccgaatatga tggaaaagaa aattgaataa aatcttgtcc
    60301 ttaaaaaagt caatcttggt atacatggaa accgtatcaa tcagatttga aatattgtag
    60361 aaaaattcac catcaaattt ctccgtaaag agcggattgt cctgacgttt aatgattaat
    60421 tcatccaaga tgctcgcaaa atagataatt tcctgaatac tataaaattg tgcagtctgc
    60481 ttagagtaag tttgaaaaat tttttgagaa atttccaaag cctgcttact agtattaggt
    60541 gaattttcaa tgttttgctc ctgacctata agagataaca agatcgcaaa aaacatcttc
    60601 atcctagcat ccatatctgg aaaacctgac agttgcttat taacaatctg actggccagc
    60661 ctagttctat ctgcttctaa aatatcaaag ctcccaaaat taccggttga aaaatctgct
    60721 actgagatac agtttgtcag taaaatagcc aaaaatcttc tcttaccaac tgaatcacca
    60781 gaaatccgat aacctttttg tcgttcaatt ttcagatcaa agtctaaaag acgcttatca
    60841 atatctgaaa tatcctgaat aatagttaca ttactgactt tcgtgcactc ttgcaatgct
    60901 tcattggtga caaaaccgct ctcagtcaga aggcgatagg taatcaactc ttgtctttct
    60961 tggggactat actcaactaa cacttcaagt tctgtcggca aatcatccaa ctctccagtc
    61021 aaaatatagt atttcccatg cttcgttatt tcgattccat attgctccat gctatctgtc
    61081 aaatctgata aagttcgata aattgttcta gatgaaacct gtaagatttc agtcatatct
    61141 tgcattgaaa gcttccctac atgtaggaaa gccttcaata attgttcttc tcgtttggtt
    61201 aatagcattc gtaatttaga aacctctagt tctatttgta cattctagca gccattttgt
    61261 catattctgg tgttgttact aaactatcca caataagaaa ttgagaattc ggtgctgctt
    61321 gctgcacttc tgcctgtaaa gaaatagttg ttacaatcat tatgttttta gaattaaatt
    61381 cacctaattc tgaaattttg gcagtagaaa ctggaatacg aatattcttg tttctaaaga
    61441 tagcccgaat cgtttcacag cccatagttg cagttccctg tgctttacca taagcaacta
    61501 ctacagcatc aatatggtta aggtcaattt cctgactatc tactggtgct gaagttggta
    61561 tatctccttc aatttctgct attggagaag ctcctgttaa tgaagctaca atttcatcat
    61621 aacgagggga cgctaagaaa ttatcaacag aaacatgaat agcacttgga ctcttgtctt
    61681 tagctcttgg tgtcagttct tcctgagtaa caattaatgt ttttggtgta tcaagcaaat
    61741 ttgagattgc ctgattagat actggaatct ctagacctgc ttttttaacc ttatctcgaa
    61801 gaatactagc tcccatagca gagcttccca taccagcatc gcaggcgaaa atgatttttt
    61861 ccactgagtc tgtcgaaaca actgcatcaa cagaagttga tactaactga cctttagact
    61921 gagccttagc tgcttgggta gccgcctgag cagcttcgag cgaatcctca gttgacttgt
    61981 ctgcatgaag aataagggct gctacaagga aagaaacaac tgctgctact aaaacaccta
    62041 gaagaacatt tatatggggc caaacacctt ttggcgccgt agccataatc gcaataatag
    62101 aacctggtga agctggagat ttaagaccag cgtctaagag ttgaaaagta aaagttccag
    62161 agatacctcc cgccatagca gctaaaaata gagtaggctt catcataaca taaggaaagt
    62221 aaatttcatg aatccctccg aagaaatgaa taaccattgc cccccaagaa gaagatttag
    62281 cagaaccttt accgaataca gcataagcta atagaattcc caggcctggt ccaggattag
    62341 cttccaatag gaagagaatt gacttaccag cttgaactac ctgttctact cccagaggag
    62401 taaaaatgcc atgattgagg gcattattga ggaaaaggac tttagccggt tcgatgataa
    62461 tattagccat aggaaggagg cgagcattga caatagcctc aacaccattc ccaacagctc
    62521 cagtaagagt cgatacgact ggaccgattg cgtagaaagc caaaagcaat aatgcaaaac
    62581 caacgagacc agctgagaag ttattaacta acatttcaaa tccgggacga attttttctt
    62641 ggaacttctc atcaaatttc ttgatagtcc atcctcccag tgggcccatt accatagctc
    62701 cgataaacat aggaacacta gaacctgtga ttgcaccaac agtagcaata gctcctacaa
    62761 cggcaccacg ttggccatgg atcatatatc cacctgtgta accaatcagg attggcaata
    62821 aatacgttaa cataggacca acaacagtag ctaactgttc atttggcaga tagccatcag
    62881 cgataaagag ggcagtcaat actccccaag caataaatgc tccaatattg ggcataacca
    62941 tatttgaaag cgatgtccct agtttttgaa ccctgacttt caatgatact ttttcttcca
    63001 ttagatcatc ctccttttct taaaactagt atatacaaag ttaaaaacct ttaaaactaa
    63061 agttttgtca cagattttgt gtcaaaacat tacttttgac gaggctgggc aaaaaggctt
    63121 aaaaattata aaacgcatca tatcaggtgt acatgaacta caccccaaaa gttagac
//
LOCUS       DAVKXA010000005        59825 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKXA010000005 DAVKXA010000000
VERSION     DAVKXA010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59825
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.005"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..201
                     /locus_tag="VW883_000351"
     CDS             <1..201
                     /locus_tag="VW883_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEV0273545.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
     gene            complement(431..1411)
                     /gene="dusB"
                     /locus_tag="VW883_000352"
     CDS             complement(431..1411)
                     /gene="dusB"
                     /locus_tag="VW883_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0273546.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1398..2270)
                     /gene="hslO"
                     /locus_tag="VW883_000353"
     CDS             complement(1398..2270)
                     /gene="hslO"
                     /locus_tag="VW883_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0273547.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2435..3862
                     /locus_tag="VW883_000354"
     CDS             2435..3862
                     /locus_tag="VW883_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0273548.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSENENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            4021..5529
                     /gene="glpK"
                     /locus_tag="VW883_000355"
     CDS             4021..5529
                     /gene="glpK"
                     /locus_tag="VW883_000355"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0273549.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5571..7397
                     /gene="glpO"
                     /locus_tag="VW883_000356"
     CDS             5571..7397
                     /gene="glpO"
                     /locus_tag="VW883_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0273550.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7467..8171
                     /locus_tag="VW883_000357"
     CDS             7467..8171
                     /locus_tag="VW883_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0273551.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     LGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8362..8565
                     /locus_tag="VW883_000358"
     CDS             8362..8565
                     /locus_tag="VW883_000358"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273552.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8652..9260)
                     /locus_tag="VW883_000359"
     CDS             complement(8652..9260)
                     /locus_tag="VW883_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273553.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10350..11626
                     /gene="ltrA"
                     /locus_tag="VW883_000360"
                     /pseudo
     CDS             10350..11626
                     /gene="ltrA"
                     /locus_tag="VW883_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            12086..13264
                     /locus_tag="VW883_000361"
     CDS             12086..13264
                     /locus_tag="VW883_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0273554.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13578..13709
                     /locus_tag="VW883_000362"
     CDS             13578..13709
                     /locus_tag="VW883_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0273555.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13730..15280
                     /gene="dltA"
                     /locus_tag="VW883_000363"
     CDS             13730..15280
                     /gene="dltA"
                     /locus_tag="VW883_000363"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0273556.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPMVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLSLTPNGKIDIKG
                     LINEVNKR"
     gene            15277..16521
                     /gene="dltB"
                     /locus_tag="VW883_000364"
     CDS             15277..16521
                     /gene="dltB"
                     /locus_tag="VW883_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0273557.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16535..16774
                     /gene="dltC"
                     /locus_tag="VW883_000365"
     CDS             16535..16774
                     /gene="dltC"
                     /locus_tag="VW883_000365"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0273558.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16767..18035
                     /gene="dltD"
                     /locus_tag="VW883_000366"
     CDS             16767..18035
                     /gene="dltD"
                     /locus_tag="VW883_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0273559.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18190..18630
                     /gene="adcR"
                     /locus_tag="VW883_000367"
     CDS             18190..18630
                     /gene="adcR"
                     /locus_tag="VW883_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0273560.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18630..19334
                     /locus_tag="VW883_000368"
     CDS             18630..19334
                     /locus_tag="VW883_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0273561.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19327..20133
                     /locus_tag="VW883_000369"
     CDS             19327..20133
                     /locus_tag="VW883_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0273562.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20143..21648
                     /gene="adcA"
                     /locus_tag="VW883_000370"
     CDS             20143..21648
                     /gene="adcA"
                     /locus_tag="VW883_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0273563.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22819..23592)
                     /locus_tag="VW883_000371"
     CDS             complement(22819..23592)
                     /locus_tag="VW883_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0273564.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            23768..25171
                     /locus_tag="VW883_000372"
     CDS             23768..25171
                     /locus_tag="VW883_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0273565.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLVDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25286..25924
                     /locus_tag="VW883_000373"
     CDS             25286..25924
                     /locus_tag="VW883_000373"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0273566.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25936..26376
                     /locus_tag="VW883_000374"
     CDS             25936..26376
                     /locus_tag="VW883_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0273567.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26369..26800
                     /locus_tag="VW883_000375"
     CDS             26369..26800
                     /locus_tag="VW883_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0273568.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26791..27261
                     /locus_tag="VW883_000376"
     CDS             26791..27261
                     /locus_tag="VW883_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0273569.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27286..28059
                     /locus_tag="VW883_000377"
     CDS             27286..28059
                     /locus_tag="VW883_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0273570.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            28056..28856
                     /locus_tag="VW883_000378"
     CDS             28056..28856
                     /locus_tag="VW883_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0273571.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28915..31209
                     /locus_tag="VW883_000379"
     CDS             28915..31209
                     /locus_tag="VW883_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0273572.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31219..34335
                     /locus_tag="VW883_000380"
     CDS             31219..34335
                     /locus_tag="VW883_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0273573.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGLVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34418..36184
                     /locus_tag="VW883_000381"
     CDS             34418..36184
                     /locus_tag="VW883_000381"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0273574.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAILGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36330..37481
                     /locus_tag="VW883_000382"
     CDS             36330..37481
                     /locus_tag="VW883_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0273575.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37626..38510
                     /locus_tag="VW883_000383"
     CDS             37626..38510
                     /locus_tag="VW883_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0273576.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38864..39115
                     /locus_tag="VW883_000384"
     CDS             38864..39115
                     /locus_tag="VW883_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0273577.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQATE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            39103..39393
                     /locus_tag="VW883_000385"
     CDS             39103..39393
                     /locus_tag="VW883_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273578.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQTEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQKLMNKAVKDEVAQI"
     gene            complement(39799..41130)
                     /locus_tag="VW883_000386"
     CDS             complement(39799..41130)
                     /locus_tag="VW883_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0273579.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(41152..42663)
                     /locus_tag="VW883_000387"
     CDS             complement(41152..42663)
                     /locus_tag="VW883_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0273580.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42874..43821)
                     /gene="arcC"
                     /locus_tag="VW883_000388"
     CDS             complement(42874..43821)
                     /gene="arcC"
                     /locus_tag="VW883_000388"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0273581.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(43986..45002)
                     /gene="argF"
                     /locus_tag="VW883_000389"
     CDS             complement(43986..45002)
                     /gene="argF"
                     /locus_tag="VW883_000389"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0273582.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(45060..46289)
                     /gene="arcA"
                     /locus_tag="VW883_000390"
     CDS             complement(45060..46289)
                     /gene="arcA"
                     /locus_tag="VW883_000390"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0273583.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLDVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            47045..48724
                     /locus_tag="VW883_000391"
     CDS             47045..48724
                     /locus_tag="VW883_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0273584.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48764..50848)
                     /locus_tag="VW883_000392"
     CDS             complement(48764..50848)
                     /locus_tag="VW883_000392"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0273585.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALQQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGISLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            51020..52300
                     /locus_tag="VW883_000393"
     CDS             51020..52300
                     /locus_tag="VW883_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0273586.1"
                     /translation="MVYSKEIVREWLDEVAERAKDYPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWLIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52391..55036
                     /locus_tag="VW883_000394"
     CDS             52391..55036
                     /locus_tag="VW883_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0273587.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVATFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSMDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            55120..55989
                     /locus_tag="VW883_000395"
     CDS             55120..55989
                     /locus_tag="VW883_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0273588.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLTWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            55983..57863
                     /locus_tag="VW883_000396"
     CDS             55983..57863
                     /locus_tag="VW883_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0273589.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVENILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58241..58603
                     /locus_tag="VW883_000397"
     CDS             58241..58603
                     /locus_tag="VW883_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273590.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHTFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(58675..59524)
                     /locus_tag="VW883_000398"
     CDS             complement(join(58675..59109,59111..59524))
                     /locus_tag="VW883_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0273591.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDARFKRLVGVQRTTFEEML
                     AVLKTTYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLIRRSQ
                     WVEATLVQSGVTISRTPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIV
                     TSQGRIVSLDITVNYCHDMKLFKMSRRNIGQAGKILADSGYQGPMKIYPQAQTPRKSS
                     KLKPLIAEDKAYNHALSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLIAGII
                     NHELGF"
     gene            complement(59469..59651)
                     /locus_tag="VW883_000399"
     CDS             complement(59469..59651)
                     /locus_tag="VW883_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0273592.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
BASE COUNT        18020 a        10969 c        13129 g        17707 t
ORIGIN      
        1 aatgctaacg gttcgatggc aacaggttgg ctgaaagatg gagatacatg gtactatctt
       61 gaagcatcag gggctatgaa agaaagccaa tggttcaaag tatcagacaa atggtactat
      121 gtcaatggct caggtgccct tgcagtcaac acaactgtag gtggctatag agtcaatgcc
      181 aatggtaaat gggtaaacta aacctaatgt aactcgttaa tgctggcttc ctgtaagaac
      241 tctttaaagt attccctaca aataccatat cctttcagta gatactatac ccttgtagga
      301 agtttagatt aaaaaataac tctgtaatct ctagccggat ttatggcgct agagactacg
      361 gagttttttt gatgaggaaa gaatggcggc actcaagaga ctctttaaga gagttacggg
      421 ttttaaacta ttaagccttc tccaattgca agagagcttc aatctctgcc agggtgctag
      481 cttgtgaaat ggctccacgg agtttggcag cgccagatgt tccacggaga tagtgaggag
      541 cgaggccgcg gaattcacga acggcgacgt tttctccttt gaggttaatc aatcgtttca
      601 agtgttcgta ggcgatcttc atcttgtctt caaaggtcaa atcaggtagg atttctcctg
      661 tttcaaagta atggttgatt tggttgaaga ggtaaggatt tcccatggca gctcggccaa
      721 tcatgactgc gtcagcacca acttcttcga tgcgttgctt ggcttcttgg acagtacgga
      781 tatcaccgtt ggcgatgaat ggaatcttgg ttagagcttg ggcaaccttg taaagggtct
      841 caaggtctgc gtggccagta tacatttgtt cacgggtacg gccatgcatg gcgagggcag
      901 aaacacctgc agcttcagca gcgagggcat tttctactgc cagagatggg tccgcccatc
      961 cggtacgcat tttgacagta agggggatat caaggacaga ctgaaccttg ttgatgatag
     1021 agtagatctt gtcaggatcc ttgagccaca tagctccagc ttcgttcttc acgattttgt
     1081 tgacagggca gcccatgttg atatcgacga tatcggtctt ggtgttttct tggatgaatt
     1141 ctgctgcgcg tgctaggctg tcttcatcgc taccaaaaag ttggatagag acagggtttt
     1201 cgccctcatc gatatgaagc atgtgcaggg ttttttcgtt gttgtattgg attcctttgt
     1261 cagagaccat ttccattaca acgagtccag ctccgagctc ttttgcgatg gtacgaaagg
     1321 ctgagttggt cacgccagcc ataggcgcta aaacggtacg attgggaatc tcaacattgc
     1381 caatcataaa aggtgtatta agatttgtca cgaatgagtt cctccaggtc cttttcatca
     1441 aagttgtaag tagtttggca gaattgacaa gtgatttctg ccccgtggtc ttcttctttc
     1501 atttcctgta agtctgagct tggaaggctg gcaagagcgt tcataaagcg ttcatggcta
     1561 cagtcacatt ggaaacggat ttcttcttca gaaagacgct tgtaggcttc gtccccgtag
     1621 atagccttga ggagggcttc gatatggtcg tcgctttcga gaagagtaga gatagctggc
     1681 atttcttgga tgcgtttttc aaagcgagca atctcttctt tcttggctcc tggcaagact
     1741 tgaactagga aaccacctgc aaccttgacc ttgtcttcct cgtccaaaag gacattgagg
     1801 ccgaccgctg aaggcgtttg ttggctttca gtaaggtaaa aggcaaggtc ttcaccgatt
     1861 tctccggaga tgaggggagt tatagagttg taaggatttc cagtaccgta gtctgtgata
     1921 acgaggaatt gaccatttcc aacaaaaggt ccgactagga cttcaccagt cgcagtcttt
     1981 ttgatgtcaa caccaggatt ttgaacgtag cctttgacgt tccccttggt atcagcgacg
     2041 gtgataatag cacctagaga gctagatccc aacaccttaa ctgtaagttt ggtatttcct
     2101 ttttcattgg ctgcgagaat ctggctagcg ataagagttc gaccaagcgc tacagttgag
     2161 ctagcttggg tttggtgttt ttcttgagca gtgcggacgg tttccgtgct gtcaaggaca
     2221 aaagcacgaa aggctccgct ttctgatata gttttaataa ttttattcat agctactatt
     2281 ttagcataaa aatgcccaga gggggagccg tgtgtttact gattttcagg ataatggacc
     2341 aggaaatcag catgaaaata aaaagagaaa cagattattt cagcatttgt aagatttatg
     2401 ctatgcttaa ggtagaaaat gaaaggggta acaaatgtat ttaggagatt tgatggagaa
     2461 agctgagtgt ggtcaatttt caatcctttc ctttctatta caagagtctc agacgaccgt
     2521 caaggctgta atggaagaaa caggattttc aaaagcaacc ctaaccaaat atgtcaccct
     2581 gctcaatgac aaggctttgg atagtggctt agagctgact attcactcag aaaatgaaaa
     2641 tttgcgtctg tctatcggtg cagctaccaa ggggagagat attcggagct tatttttgga
     2701 gagtgctgtt aaataccaga ttttggttta tcttctctac caccaacagt ttttagccca
     2761 tcagctggct caagaattgg tgattagcga ggctacgctt ggtcgtcact tggctggttt
     2821 aaatcagatt ctgtcagaat ttgatttatc catccaaaat ggacgttggc gaggtccaga
     2881 gcatcagatt cgctatttct atttctgtct tttccgaaag gtctggtcga gtcaggaatg
     2941 ggaaggtcac atgcagaaac cagagagaaa acaggagatt gccaatttag aggaaatctg
     3001 cggtgcaagt ttgtctgtgg ggcagaaatt ggacttggtt ctctgggctc acatcagtca
     3061 acaacgtctt cgggtcaatg cttgtcagtt tcaagtcata gaagagaaaa tgcgagggta
     3121 ttttgacaat atcttttatc ttcgtttgct gagaaaggtt ccgtcctttt ttgctgggca
     3181 acatattcca ctaggagttg aggatggtga gatgatgata ttcttctctt ttctcctatc
     3241 tcatcgcatt cttcctcttc atactatgga gtatattctt ggttttggag ggcagttggc
     3301 agatttactg acgcaattga ttcaagaaat gaagaaggag gaactattgg gggattatac
     3361 agaggaccat gtcacctatg aactcagtca gctttgtgct caagtctatc tctataaggg
     3421 ctatatttta caggatcgct acaagtacca gttagagaat cgtcatccat atttactgat
     3481 ggaacatgat tttaaagaga cagcagagga gatttttcat gctctaccta cttttcaaca
     3541 ggggacagat ttagataaga agattctctg ggaatggctc cagttaatcg aatatatggc
     3601 tgaaaacggt ggccagcata tgcggattgg tctggatttg acatctggtt ttcttgtctt
     3661 ttcaaggatg gcagccattt tgaaacggta tttggaatac aatcgtttta ttaccattga
     3721 agcttatgac cctagtcggc attatgattt gctggttacc aataacccga ttcataagaa
     3781 ggaacagaca ccagtctatt atttaaaaaa tgacttggat atggaggatt tggtagcgat
     3841 tcgccagtta ttattcactt aaaaggcttg gttaatccag gtcttttttg tgaaattcac
     3901 acaatctcct cacatttttt taaaaattaa aaaaagttga taaacaagaa agcgctttat
     3961 tttgtatact agtaagtgta aagaggaaac acctcaagat ctttatcagg aggacagtac
     4021 atgtcacaag aaaaatacat catggccatt gaccagggaa ctacaagttc tcgtgccatc
     4081 attttcaaca aaaaagggga aaaggttagc tcgagtcaaa aagagtttac ccagattttc
     4141 cctcaggcag gttgggttga gcacaatgcc aatgaaattt ggaactctgt tcagtcagtt
     4201 attgcgggtg ctttcatcga aagtggtgtc aagccaaatc aaatcgaggc aatcgggatt
     4261 accaaccaac gtgaaacaac ggttgtctgg gataagaaaa caggacttcc tatctacaat
     4321 gctatcgttt ggcagtcacg ccagacagca cctttggctg agcaactaaa aagccaaggt
     4381 tatgtggaaa aattccatga aaagactggt ttgattattg atgcttactt ctctgctacc
     4441 aaggttcgtt ggattttgga tcatgtagaa ggtgctcaag agcgagcaga aaaaggggaa
     4501 ttgctctttg gtactatcga tacttggttg gtttggaaat tgactgacgg tgcggctcac
     4561 gtgactgact actcaaatgc agctcgtacc atgctttata acattaaaga actcaaatgg
     4621 gatgatgaga ttttggaaat ccttaacatt ccgaaggcta tacttccaga agttcgttct
     4681 aactccgaaa tctacggcaa gacagctcca ttccatttct acggtggaga ggtgccaatc
     4741 tcaggtatgg ctggggacca acaagcagcc ctctttggac agttggcttt tgagccaggt
     4801 atggttaaga atacttatgg aacaggctct ttcatcatca tgaatactgg ggaagagatg
     4861 cagttgtctg aaaacaacct cttgacaacc attggttacg gaatcaacgg taaggtttat
     4921 tatgccttgg aaggttctat cttcatcgca ggaagtgcta ttcagtggct tcgtgacggt
     4981 cttcgcatgg ttgaaaattc accagaatct gaaaaatacg ctcgtgattc tcacaacaac
     5041 gatgaagttt atgtcgttcc agcctttaca ggtctaggcg ctccatactg gaaccaaaat
     5101 gctcgtggtt ccgtctttgg tttgactcgt ggaacaagca aagaagactt tatcaaggcg
     5161 actttgcaat ctattgctta tcaagtgcgt gatatcatcg acaccatgca agtggatact
     5221 cagaccgcca ttcaagtact gaaggtggat ggtggtgcag ccatgaacaa cttcctcatg
     5281 cagttccagg cggatatttt aggcattgac attgcacgtg ctaaaaacct ggaaacaaca
     5341 gctctaggag cggccttcct agcaggtttg tcagtagggt actggaaaga cttggacgag
     5401 ttgaaactct tgaacgagac aggagaactc tttgagccat ctatgaacga atctcgcaag
     5461 gaacaactct acaagggctg gaagaaggct gtgaaagcaa ctcaagtctt tgcggaagta
     5521 gacgactaat actggcagaa taaagcgatt tatttagaaa gtgtgtaaat atggaatttt
     5581 caaagaaaac acgtgaattg tcaattaaaa aaatgcagga acgtaccctg gacctcttga
     5641 ttatcggtgg aggaatcaca ggagctggtg tagccttgca ggcggcagct agcggtcttg
     5701 agactggttt gattgaaatg caagactttg cagaaggaac atctagtcgt tcaacaaaat
     5761 tggttcacgg aggacttcgt tacctcaaac aatttgacgt agaagtggtc tcagatacgg
     5821 tttctgaacg tgcagtggtt caacaaatcg ctccacacat tccaaaatca gatccaatgc
     5881 tcttaccagt ttacgatgaa gatggagcaa cctttagcct cttccgtctt aaagtagcca
     5941 tggacttgta cgacctttta gcaggtgtga gcaacacgtc agctgcgaac aaggttttga
     6001 gcaaggatca agtcttggaa cgccagccaa acttgaagaa ggaaggcttg gtaggaggtg
     6061 gagtgtatct tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac atcaaacgtg
     6121 ccaaccaaga cggtgccctc attgccaacc acgtgaaggc agaaggcttc ctctttgacg
     6181 aaagtggcaa gattacaggt gttgtagctc gtgatctctt gacagaccaa gtatttgaaa
     6241 tcaaggcccg tctggttatt aatacaacag gtccttggag tgataaagta cgtaatttgt
     6301 ctaataaggg aacgcaattc tcacaaatgc gcccaactaa gggagttcac ttggtagtgg
     6361 attcaagcaa aatcaaggtt tcacagccag tttacttcga cacaggtttg ggtgacggtc
     6421 gtatggtctt tgttctccca cgtgaaaaca agacttactt tggtacaact gatacagact
     6481 acacaggtga tttggagcat ccaaaagtaa ctcaagaaga tgtagattat ctacttggca
     6541 ttgtcaacaa ccgctttcca gaatccaaca tcaccattga tgatatcgaa agcagctggg
     6601 caggtcttcg tccattgatt gcagggaaca gtgcctctga ctataatggt ggaaataacg
     6661 gtaccatcag tgatgaaagc tttgacaact tgattgcgac tgttgaatct tatctctcca
     6721 aagaaaaaac acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt agcacatctg
     6781 agaaatattt ggatccatct gcagtttctc gtgggtctag cttggaccgt gatgacaatg
     6841 gtcttttgac tcttgctggc ggtaaaatca cagactaccg taagatggct gaaggagcta
     6901 tggagcgcgt ggttgacatc ctcaaagcag aatttgaccg tagctttaaa ttgatcaatt
     6961 ctaaaactta ccctgtttca ggtggagaat tgaacccagc aaatgtggat tcagaaatcg
     7021 aagcctttgc gcaacttgga gtatcacgtg gtttggatag caaggaagct cactatctgg
     7081 caaatcttta cggttcaaat gcaccgaaag tctttgcact tgctcacagc ttggaacaag
     7141 cgccaggact cagcttggca gatactttgt cccttcacta tgcaatgcgc aacgagttgg
     7201 ctcttagccc agttgacttc cttcttcgtc gtaccaacca tatgctcttt atgcgtgata
     7261 gcttggatag catcgttgag ccagttttgg atgaaatggg acgattctat gactggacag
     7321 aagaagaaaa agcaacttac cgtgctgatg tcgaagcagc tctcgctaac aacgatttag
     7381 cagaattaaa aaattaagaa aaaataaaag aggtggaggg cagcattcct tgtcgctcgt
     7441 cccttctttt taatggagac agaaagatga tgaatgaatt atttggagaa tttctaggga
     7501 ctttaatcct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt ccaaaaacca
     7561 agagcaacag tgcaggttgg attgtgatta ctatgggttg ggggattgca gttgcggttg
     7621 cagtctttgt atctggcaag ctcagtccag ctcatttaaa tccagctgtg acagttggtg
     7681 tagctttaaa aggtgacttg ccttgggctt ccgttttgcc ttatatctta gcccagttcg
     7741 caggggctat gctgggtcag attttggttt ggttgcaatt caaaccgcat tatgaggtag
     7801 aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc aaggatactg
     7861 tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca atctttgctt
     7921 tgggtcttta cgattttcag gcaggtctcg gaacctttgc agtgggaact ttgattgtcg
     7981 gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct cgtgaccttg
     8041 gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga gactggtctt
     8101 acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg cttgtattct
     8161 cacttttcta atctagaaaa caattatgtt gatagagctt gggcaagagc ccaatttcag
     8221 caaaaaatga agtaaatctt ctcataataa aacgcatcat atcaagcacg aaaattccac
     8281 gaggtcaact acagtcagaa agctgaacaa caagccaaaa cgcccaaaaa aggcggcaaa
     8341 aagcaagcac ctgcaagcaa cgtgccgaaa tggtcaaatc ctgattatgt caacgaatta
     8401 gacccaaaaa tcgttgatat gctagtagaa tttcacaagt cacaaggcac tttggaaact
     8461 cccgaggcgc aagcagaaat cgcccaaaaa cgtgaagaaa tcgagcaaag gagagctgag
     8521 cttgagggta aaaaacaaga gcttttgaac cgcttgaaca aatagagttt cgcaagtatt
     8581 atgcttacaa attacttgag caattaacta aaatataaac cctgccttta tatctaggca
     8641 gggtttatat tttagaaatt cacgtaggtt gttacggttt ttacataccc agtatagttt
     8701 gagtttctat agtattcagt gataaacttc cattttcttt gagcaacatg gatataagta
     8761 cttgttatgt agtatggata tgggctttgt gaatccaagt aagactgata agcttgtata
     8821 ccaaaatatg ctccaccaat tattgcaccc catggacccc ccaataaagc acctatccta
     8881 ccaatcatat aactgattcc agcaccagtc atgaagttag cgaatgtgtt agcttgttta
     8941 ttcccatgta ttgtgttgac gtaattccaa acattaggat cgtatgatct aaaagatata
     9001 tttaggtcga tttcattctt ttgataagcc atataaaatg ccccattgat atagacgccg
     9061 tcagcacgtc gttcaatagt gtctacactt ccatctggat tgacaacctc aagaacttca
     9121 tcgcttaaaa tatttacttg cgtatctccg aaccgcactg atgagccatt ctcaaactga
     9181 gcctcaccag atacaacttt agagtttgcc gataagctat catcagcaaa aacaacaagc
     9241 gacggggaaa tgctagacat acagaaaaca gacataacta gcaaacacat gcatttaaac
     9301 atcttagaca taacggaaac tcctttgtat ttttgatttt tttcaacttt tattatacaa
     9361 taaaaccaaa taaaaagaaa gcggtaacaa tatgcttaat gcgaaaattt tttatatatt
     9421 tttatgtttg atcgttatcg aaactacagg cttgttgttg ttgaaaagag gtctcgaaat
     9481 gggttattta gacacagaag ctattatcct cgcagttttt tcatttgctt tttacaacct
     9541 atgttcattc gcttgggtct gctctacaat aaaaaacaat aaaaaataaa tagacgtatt
     9601 ttcaaaaaaa aaaaaaatgc atatttatct tagcaaaacg acaatttaaa tcgtcgtttt
     9661 tttgtagtac gacgggcatg tcgtatatct gaggtgtaag tcctcggtgg gcacctgcta
     9721 ccggtgaacc caatagcgat tcccaagcct gactatcgtg aggtagcagg gagaggaagg
     9781 gatagcgaaa tcgtggctct acgaacagga acgtgatagt aaggcgtata tagcggataa
     9841 ggaggcttca aactctaaag tccaaaaagg tagtcgtaac ctatatgtgt aaatcacgag
     9901 agtaattgaa ttcggactaa ggtttgtgtg aaaaagataa atctttctag agtctaaaga
     9961 ctctgcgtca gatttcctat tttcactgta accttttaac gtcctcatat cttgtataaa
    10021 cgaggaaaga tgtacgactt atcccgtgag gtttcatgag cgctgaaagc gtagtaacaa
    10081 cgaatcatga gaagtcagcc gagcccatag tagtgaggaa acttccgtaa tggaagtgga
    10141 gcgaaggggt gaatactcaa acagtctggg gagagactgt ttgaggtctg tcgctagaaa
    10201 gagaaaacga cagatcgaag taatcctact tcacttgtgt ctgtaaaatg agtggtctga
    10261 tagaactgga ctttgacacg taatgactag atgaaggttc accaatataa gatgtccctc
    10321 aggcaccaaa acaagaaagg aatacgcaca tgtcaaaact gctagataag atattatcac
    10381 gcgaaaatat gctggaagcc tacaatcaag taaaatccaa taaaggctca gctgggattg
    10441 atggaatgac tatcgaagag atggataatt atctcagaca aaactggcgc ttgactaagg
    10501 aactgataaa acagagaaaa tataagcctc aaccagttct taaagttgag atacctaaac
    10561 cagacggagg catccgtcaa ctaggaattc caacagttat ggatagaatg attcaacagg
    10621 ccattgtcca agtcatgagc cccatttgtg aaccccattt ctcagatacg agttatggtt
    10681 tcagaccaaa taggtcatgt gaaaaagcca tcatgaagct cttagaatac ttaaatgacg
    10741 gctatgagtg gatagtggat atagacctag agaaattttt cgatacagtt cctcaagata
    10801 gattgatgtc cttagtacat aacattatcg aagacggaga tacggaatcc ttgattcgta
    10861 agtatcttca ttcaggtgtt atcattaatg gtcaacgtta taaaacacta gttggtacac
    10921 cacagggagg aaatttatct cctctcttat ccaatatcat gcttaatgaa ttggacaagg
    10981 aattagaaaa gaggggactt cgatttgtgc gctacgcaga tgattgtgtg atacggtcgg
    11041 aagcgaggca gccgctaagc gtgtgatgta ttcagtcagt cgttttattg agaaacggct
    11101 aggtttgaaa gtaaacatga ccaagactaa gattaccaga ccaagagagt tgaaatatct
    11161 aggttttggg ttctggaaat catcagatgg ttggaaaagt cgtccacatc aagatagtgt
    11221 tcggagattt aagcttaaat tgaagaaact aacacagagg aaatggagta tagacctaac
    11281 aagacgtatt gagcaactga atttgtctat tcgaggatgg ataaactatt tctcattggg
    11341 aaatatgaaa agtatagtcg ccagcataga tgagcgcttg cgtactcgcc tacgagtgat
    11401 tatctggaag caatggaaga agaaatcgag acgattatgg ggattgctta agttaggagt
    11461 tcctaaatgg atagcagata aggtatctgg ctggggcgac cattatcaat tagtagctca
    11521 gaagtcggta cttaaacgtg ctatatcaaa accagtcctg gaaaaacgtg gactggtttc
    11581 gtgtttggat tattaccttg aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg
    11641 aacggcacgt acggtggtgt gagaggggct agagattatc ccctactcga ttaactcccc
    11701 tgaaatttat tttaattatg caaatttcac gtatttttga tgctgagacg acgatcctgg
    11761 gaacttttca gatatttttt tgactatcta aatctatcat tagaaaagct tagagcgcca
    11821 aaggatttga gcgtttttct gatttttaag actttttcca gtctcttttt cgattgaaga
    11881 tgtaattatt ctactaacta actaactaac ttcttagtac tagccaacaa cgataatcat
    11941 aattcctcct aaaattagga ataataaagg caatagtttt tgttttttca tgtaaaaaac
    12001 ctcacttttg ttttctgcta ttttatgcta aaatattaaa aatcaaattt aattccaaag
    12061 tttgtaacta aagggggagc gctacatgtc taattcattt gtcaagttgt tagtctctca
    12121 attatttgca aatttagcag atattttctt tagagtaaca atcattgcta acatatacat
    12181 tatttcaaaa tcagtaattg ccacatcact agttcctatc ttaataggaa tatcctcttt
    12241 tgttgcgagt cttttagttc cgttggttac taaaaggtta gcgctaaata gggttttatc
    12301 tttatctcaa tttggaaaga ctatattatt ggcgatactg gtaggaatgt ttaccgtaat
    12361 gcaatccgta gcgcctttgg tgacctatct atttgttgtt gcaatttcca tactagatgg
    12421 ttttgcagca cccgtttcct atgctattgt gccacgctat gcgaccgatt tgggtaaggc
    12481 taattcagcc ttatcaatga ctggtgaagc tgttcaattg ataggttggg gattaggtgg
    12541 actcttgttt gcaacaattg gtctgttacc taccacgttt atcattttag tcttgtatat
    12601 catttctagc tttctgatgt tatttcttcc taacgctgaa gtggaggtgt tagagtcaga
    12661 aactaatctt gaaattttgc tcaaaggttg gaagttagtt gctagaaacc ctagattaag
    12721 actttttgta tcagcaaatt tattggaaat tttttcaaat acgatttggg tttcttccat
    12781 tatacttgtt tttgtaacgg agttattaaa taaaacggaa agttactggg gatattctaa
    12841 tacagcatac tctattggta ttataattag tggcttaatt gcttttaggc tatctgaaaa
    12901 gttccttgct gctaaatggg aaagtattct ttttcctctt gtagctatgg caatagtgac
    12961 actgactatt ctatattttc caaacgcaca gatgttttta ttattttcag ctttagttgg
    13021 tatgttatcg caactaaaag aagttcctga aagtgtattt cttcaggaaa cagtagagga
    13081 aaatcattta gttaatgtct attccgttct tgaagtgatt tctacattag cattttcagt
    13141 atttgttttg ctaatgagct atattactga gagttttggt attagcatca gtttttggct
    13201 atcagccatt tgtctgatga tagaagctat tttaatttat atcagacgag attattttaa
    13261 atgagagagt ggttaaaaag tctttaaaaa tcagaaaagc gcatagtatc aggtgttgaa
    13321 aaaacttgat attgtgtgtt ttattatggg aagatttact tcattgtctc ctgaaatgga
    13381 gttttgaagc aggatcactc tatttgaaaa tatacataga aaaaccgcat aatccttaaa
    13441 ataagctgaa atctattgga aacatacggt aaacaattga aaagatacta tataaagtgg
    13501 tacaatggta gaaaaataag ctagtaagaa tcactcttat tttagcgaaa aattacagaa
    13561 atgaatggtt tttcttgatg aaacagagaa aagaattgta cctctttctt ggtcggacag
    13621 ccttgtattt tcttatcttt ctagggctgc tttacttctt tagctatctt ggtcagggtc
    13681 aaggaagctt tatctataat gaattttaac ttgaaggaga atccctattg tgtcaaataa
    13741 accaatagca gatatgattg aaaccattga gcattttgct cagacacagc ctagctatcc
    13801 tgtctataat gttttggggc aggaacacac ttatggcgat ttaaaggctg attcggatag
    13861 tttggctgca gtcattgacc aactaggctt gcctgaaaag tctcctatgg ttgtttttgg
    13921 tggccaagaa tatgaaatgt tggcaacctt tgtagcgctg actaagtcag gtcatgccta
    13981 cattccaatt gatagccatt cggccttgga gcgagtttca gctattttag aagtagcaga
    14041 gccaagcttg attattgcca tttcagcctt tcccttggag caggtttcta caccaatgat
    14101 aaatctagct caggttcaag aagcctttgc ccaagggaac aactatgaaa tcacgcatcc
    14161 agtcaaggga gatgataatt actacattat ctttacttct ggtacgactg gtaagcctaa
    14221 gggagtgcag atttcacatg ataatctcct cagctttaca aactggatga ttacggataa
    14281 ggaatttgcg acaccgagtc gtccgcaaat gctggcacag ccaccttatt cttttgactt
    14341 gtctgtcatg tattgggcac cgaccttggc acttggtggt acgcttttca ctcttccttc
    14401 agtcatcact caggacttta agcaactctt tgcggctatc ttttcattgc caatcgctat
    14461 ctggacatca acaccatcct ttgcagatat ggccatgtta tctgaatact tcaacagtga
    14521 gaaaatgcct ggaatcacgc atttctactt tgatggtgaa gaattgacgg tcaaaacagc
    14581 tcaaaaactg cgcgagcgtt tcccaaatgc ccgtatcatc aatgcttacg gcccaacaga
    14641 agcgacagta gctctgtcag cagttgccgt gacagacgag atgttagcga ctctcaaacg
    14701 cctaccaatc ggctatacca aggctgattc tccaaccttt atcattgacg aggaaggaaa
    14761 taaactgcca aatggcgaac agggagaaat cattgtttct gggccagctg tttcaaaagg
    14821 ttatatgaaa aatcctgaaa aaacagcaga agccttcttt gagtttgaag gtctgccagc
    14881 ctatcacaca ggcgatgtgg gaaccatgac agatgagggc ttgcttctct acggcggacg
    14941 catggacttc cagattaagt ttaacggtta ccgcattgag ttagaagatg tctctcaaaa
    15001 cctcaacaag tctcgcttta tcgaatctgc tgtcgcagta ccgcgctata acaaggacca
    15061 caaggtacaa aatctattgg cttatgtcat cttaaaagac ggtgttcgtg agcagtttga
    15121 gcgagatatc gatattacca aggccatcaa ggaagacctg acagacatca tgatgtccta
    15181 tatgatgcca tctaaattcc tttaccgaga cagtttgtca ctaactccaa atggaaagat
    15241 tgacatcaaa ggattgatta acgaggtgaa taagagatga tggagttttt tcaacagctt
    15301 cctcatttag agccatatgg caatcctcag tattttgttt atgtgattgc tgcaaccttg
    15361 cccatcttta taggtctctt tttcaagaaa cgctttgcct ggtatgaagt gttggtaagt
    15421 ctcttcttta ttgtcaccat gttggtgggt ggaaagacca atcaactagc tgccttgggt
    15481 atttaccttt gctgggaaat attgctcctg cttttctaca agcattatcg aaaaagcaag
    15541 gatggcaagt gggtcttcta cttagttagt tttctgtccc tacttccgat tatctttgtc
    15601 aaggtgcaac cagctatcaa tggaacgcag tctttgcttg ggttcttggg aatttcttac
    15661 ctgacctttc gttcggttgg gattatcatc gagctgagag atggagtgat taaggatttt
    15721 accctctggg aattcctccg tttccttctc ttcatgccaa ctttctcgag tggtccaatc
    15781 gatcgcttta agcgatttaa tgaaaattat caggccattc ctgagcgaga tgagttgatg
    15841 gatatgctgg atgaatctgt ccgctatatc atgcggggct ttttgtataa gtttatccta
    15901 gctcatgttt taggagagac cttactccct cctctgaaga atttagcctt gcagtcaggt
    15961 ggcttcttta atctctatgc cttggcagtt atgtatactt ttggtctgga gctcttcttt
    16021 gactttgcag gttattctat gtttgctttg gccatctcaa acttgatggg aatccgtagc
    16081 cctatcaact ttaacaagcc ctttttatca agggatttaa aggagttttg gaatcgctgg
    16141 catatgagtc tgtccttctg gttccgtgac tttgtcttta tgcgaatggt gatggtgtta
    16201 accagaaaga aagtctttaa aaatcgtaat gtaacctcaa gcatggccta cattgtaaat
    16261 atgctgatta tgggattttg gcatggcgtg acctggtact atatcgccta tggactcttt
    16321 catggactag gcttggtcat caatgatgcc tgggttcgca agaaaaaaac gctcaataag
    16381 gaacggaaaa aagcagggaa ggctgcccta cctgagaatc gctggattca gtttcttggc
    16441 atggttgtca ctttccatgt tgtcatgttg tcattcttaa tcttttctgg attcttgaat
    16501 aatctatggt ttaaaaaata aaaggaaata aaatatggat atcaaatcag aagttattga
    16561 aattattgat gagttgttta tggaagatgt ttctgacatg atggatgaag atctttttga
    16621 tgcaggtgtc ttggatagta tgggaacggt tgagttgatt gtggagattg agaaccgttt
    16681 tgacattcgt gtccctgtaa cagagtttgg tcgtgacgac tggaatacag ctaataaaat
    16741 catagctggt attgtggagc tacaaaatgc ttaaacgctt atggatgatc ttcggaccgg
    16801 tcttgatcgc tggtttgttg gtttttctgc tcattttctt ttatcctact gagatgcatc
    16861 ataatctagg agctgaaaag cgttcagcag tggctactac tatcgatagt tttaaggagc
    16921 gaagtcaaaa agtcagagca ctatctgatc caaatgtgcg ttttgttccc ttctttggct
    16981 ctagtgaatg gcttcgtttt gacggtgctc atcctgcggt attagctgag aaatacaatc
    17041 gttcctaccg tccttatctt ttaggacagg ggggagctgc atcgcttaac caatattttg
    17101 gaatgcaaca gatgttacca cagctggaga ataaacaagt tgtgtatgtt atctcacctc
    17161 agtggttcag taaaaatggc tatgatccag cagccttcca gcagtatttt aatggagacc
    17221 agttgactag ttttctgaaa catcaatctg gggatcaggc tagtcaatat gcagcgactc
    17281 gtttactgca acagttccca aacgtagcta tgaaggacct ggttcagaag ttggcaagta
    17341 aagaagaatt gtcgacagca gacaatgaaa tgattgaatt attggctcgt tttaatgaac
    17401 gccaagcctc cttttttggt cagttttcgg ttagaggcta tgttaactac gataagcatg
    17461 tagctaagta tttaaaaatc ttgccagacc agttttctta tcaagcaata gaagatgttg
    17521 tcaaagcaga tgctgaaaaa aatacttcca ataatgagat gggaatggaa aattatttct
    17581 ataatgagca gatcaagaag gatttgaaga aattaaagga ttctcagaaa agctttacct
    17641 atctcaagtc gccagagtat aatgacttgc agttggtttt aacacagttt tctaaatcta
    17701 aggtaaaccc gatttttatc attccacctg ttaataaaaa atggatggac tatgctggtc
    17761 tacgagagga tatgtaccaa caaacggtgc agaagattcg ctaccagtta gaaagtcaag
    17821 gttttaccaa tatagcagat ttttctaagg acggcgggga gcctttcttt atgaaggaca
    17881 ccattcacct tggttggttg ggttggttgg cttttgacaa ggcagttgat cctttcctat
    17941 ccaatcccac accagctccg acttaccatc tgaatgagcg ctttttcagc aaagattggg
    18001 cgacttatga tggagatgtc aaagaatttc aatagataat ataatataga agagttcaag
    18061 aatgaaacta gttttcacgt tttttcttga ctcttttttt gcttgtgata taattaactg
    18121 gtaaacaaaa tgtcaaagaa tagtattttt ctcttaaaaa agagaagtct aaaaggaaag
    18181 gagtcagata tgagacagct agcaaaggat atcaatgctt ttttgaatga ggtgattttg
    18241 caggcggaaa atcagcatga aatcctaata ggtcattgca ctagcgaggt ggccctgacc
    18301 aatactcagg agcatatcct tatgctcttg tcagaggaat ctttaacaaa ttcagaattg
    18361 gcccgtcgtc tcaatgtcag tcaggcggca gttaccaagg ccattaagtc tttggtcaag
    18421 gaagggatgt tggaaacatc taaagattct aaagatgcgc gtgtgatttt ttatcagttg
    18481 actgacttgg ctcgtccaat cgctgaggag caccaccatc accatgagca tacactttta
    18541 acctatgaac aagtggcgac tcagtttact ccaaatgaac aaaaagtgat tcagcggttt
    18601 ttgactgctt tagtaggaga aatcaaataa tgagatatat tacggtagag gatttgtcct
    18661 tctattatga taaggagcct gttcttgaac atatcaatta ttgtgttgat agtggggaat
    18721 ttgttacctt gactggggaa aatggagcgg ctaagacgac gctcatcaag gctagtcttg
    18781 gaattctgca accacgcatt ggaaaggtgg ctatttcaaa gacaaatacg caaggtaaga
    18841 aattgagaat agcctatctt cctcaacaaa ttgccagttt taatgctggt tttccaagta
    18901 cggtctatga atttgtcaag tcgggtcgct atccgagaaa aggctggttc cgtcgtttga
    18961 atgctcatga tgaggagcat atcaaggcta gtctggactc agttggcatg tgggaacatc
    19021 gagacaaacg cttggggtct ctatctgggg gacaaaagca gcgagcggta attgcgcgta
    19081 tgtttgcttc tgaccctgat gtgtttatcc tagacgagcc gacaacgggg atggatgcag
    19141 gaagtaaaaa tgaattttac gaactcatgc accacagcgc ccatcatcat ggcaaggctg
    19201 ttttgatgat tacccatgac cctgaagaag ttaaggatta tgcggatcgc aatattcatc
    19261 tagtccgtaa ccaagactcg ccatggcgtt gtttcaatgt tcatgagaat ggccaggagg
    19321 tgggccatgc ttagtttatt atcttacgac tttatacaac gcgccttttt ggcggttatt
    19381 gctatgagtc ttttctcacc ggtattggga accttcctca tcttgcgtcg tcagagtttg
    19441 atgagtgata cccttagcca cgtctcactt tcaggtgtag cctttggtct ggttttgggg
    19501 atttctccaa ctgtttctac tattgccatt gtcttgattg cggcggtctt tctggagtat
    19561 ctccgtacgg tttacaagag ctttatggaa atcgggacag ctatcctcat gtcaacaggt
    19621 ctggctgttt ctctgattgt catgagcaag ggtaaaagct cgagttcaat gagtttggac
    19681 caatatctct ttggttcgat cgtgactatc agtgaagaac aggtcatttc cctctttgtc
    19741 attgcggcgg ttgttttgat tttgaccttt ctctttcttc gtcctatgta tatcttaact
    19801 tttgacgaag atacggcctt tgtggatggc ttgccagttc gtaccatgtc cattcttttt
    19861 aacatggtga caggggtggc tattgccctt atgattcctg cagcaggagc tcttctggta
    19921 tcgaccatta tggtcttgcc agctagtatt gccctgcgtc tggggaaaaa ctttaaatcg
    19981 gttatgctgc ttgccagtgc gattggcttt ttgggaatgg tagcaggact ttacatttcc
    20041 tactatgcag aaacacctgc aagtgcaagt attaccatta tttttgtaac tgtctttata
    20101 ctaatcagtt tagtaagacg ttttatcaaa taggagacga acgtgaaaaa aattagctta
    20161 ttactagcca gtctatgtgc cttgttttta gtggcttgtt ccaatcaaaa acaggcagat
    20221 ggtaaactca atatcgtgac aaccttttac cctgtctatg aatttaccaa gcaagtcgca
    20281 ggagatacgg ctaatgtaga actcctaatc ggtgctggga cagaacctca tgaatacgaa
    20341 ccatctgcca aggcagttgc caaaatccaa gatgcagata ccttcgttta tgaaaatgaa
    20401 aacatggaaa catgggtacc taaattgcta gataccttgg ataagaaaaa agtgaaaacc
    20461 atcaaggcga caggcgatat gttgctcttg ccaggtggcg aggaagaaga gggagaccat
    20521 gaccatggag aagaaggtca tcaccatgag tttgatcccc atgtttggtt atcaccagtt
    20581 cgtgccatta aactagtaga gcacattcgc gacagcttgt cagcagatta tcctgataaa
    20641 aaagagacct ttgagaagaa tgcagctgcc tatatcgaaa aattgcaagc cttggataag
    20701 gcttacgcag aaggcttgtc tcaagcaaaa caaaagagct ttgtgactca acacgcagcc
    20761 tttaactatc ttgccttgga ctatggactc aaacaagtcg caatctcagg cctttctcca
    20821 gatgcagagc catcagctgc tcgcttggca gaattgacag agtatgtcaa gaaaaataaa
    20881 atcgcctata tctattttga agaaaatgcc tcacaagccc ttgctaacac actttcaaaa
    20941 gaagcaggtg tcaaaactga tgtcctcaat cctttagaaa gtctgacaga agaggacacc
    21001 aaggctggag aaaactacat ttccgtgatg gagaaaaacc tcaaggcttt gaaacaaaca
    21061 acagaccaag aaggcccagc aatcgaacct gaaaaggcag aggataccaa gacagtccaa
    21121 aatggttact tcgaggatgc agctgtcaag gaccgcacct tgagtgacta tgcaggtaac
    21181 tggcaatcag tttatccttt ccttgaagac ggcacgtttg accaagtctt tgactacaag
    21241 gctaagttga ctggtaagat gacccaggct gagtacaagg cttactatac aaaaggctat
    21301 cagacagatg tgactaagat taacattact gataatacta tggaatttgt tcaaggtgga
    21361 caaagcaaga aatacactta caagtatgtc ggtaagaaaa ttttgactta caagaaaggc
    21421 aatcgtggcg tgcgtttcct ctttgaagcc acagatgctg acgctggaca attcaagtat
    21481 gttcagttta gtgaccacaa tatcgcccca gttaaggcag aacatttcca tatcttcttt
    21541 ggaggcacaa gccaagaagc cctctttgaa gaaatggaca actggccaac ctactaccca
    21601 gataacctat ctggccaaga aatcgcccaa gaaatgttgg cgcattgatg agaaatcgac
    21661 tagttcataa gagctagtcg gttttttgat actagatggc taacttcatt atagaccttt
    21721 cagaactaag ggaacctgaa aaaataaata aaactcttga aatatctgga cttatatgct
    21781 agaatgtagt tagtgtataa ggttcattag aacaccaaag cccctaacta gtgccatagt
    21841 taagggcttt tttgacgtat cttagcgatt taatgggtgt ttataggcta gtcagtcggt
    21901 ctacttctta ccatctagcc atttgcagac gaaatacaag ataattccag ctataacatc
    21961 tgctataata gtaagagcaa gctctggtat aaggctcatt agtttcacct cctctcacga
    22021 acccatagga acgtaatcgg taaccgatga caaaaatagt ataccacact aaatttagat
    22081 catcaacctc acttaatgct tgaactattg tagattatat gctaaaatgt agttaattga
    22141 taaggttcat tagaacacca aagcccctaa ctatggccgt agttaagggc ttttttgacg
    22201 tatcttagcg atttaacggg tgtttatagg ctagtcagtc ggtctactcc ttactatcta
    22261 gccatctgca gacgaaatac aagataattc cagctataac atccgctata atagtaagag
    22321 cgagctctat gataaggctc attagtttca cctcctctca cgaacccata ggaacgtaat
    22381 cggtaaccga tgacaaaaat agtataccac aataaattta gatcatcaag gtcacttaat
    22441 tcttgaaata tagggtctag gcgacaaagt ctttaaaatc agaaaaacgc ataatatcag
    22501 gtgtgcaaaa acttgatact atgcgtttta ttgtgggaag gtttactcca ttttctcctg
    22561 aaattgagtt tttgtccagc ctctgttttt ggggttgcta agaaaataat gtcatgtggt
    22621 gaatatttgt aaatcagtca gcagacagaa cgaatactct tcgaaaatct cttcacatca
    22681 tgtcagcttc gtctttccgt atatatgtga ctgacttcat cagttctatc tacaacctca
    22741 aaacagtgtt tcgagctgac ttcatcagtt ttcaaatctg tactttgagc aagctgagac
    22801 tagcttccta tttgattttc attgaatatc agaaacccat tctccatcaa ataattcgac
    22861 tgcgtctaat aatttttggt ctggcaaggt gtcagaaata aaggttgtgt atttggagag
    22921 gggattaatt ttaaaaaatc cagtcttgta aaatttagaa ctatcaatca gtaagatggt
    22981 ttcatgggct ttgtcaataa tattcttttt tgaaatagct tggctgagag aagcttcata
    23041 aacatattgg tcatcaatac ctcttgctga acaaaatgct aaatcgatat taaaatgatc
    23101 taataaagaa ttttccttat catagttgac tacggaacag gattgatgtt tgacctcgcc
    23161 agatgtgata aagattttgg agctatcttt aacagtttca gatagggttt gtgcagtatg
    23221 taaaccattt gtaaaaataa tcaaattatc aagttcagaa agatagggac agagttcgta
    23281 gacagtcgta ctggaatcaa gataaataca catgcctgac cgaataaagt ctttagcgag
    23341 actagcgatt agtctttttt gcctagtact ttctccttcc cgtatttgat gagaaagttc
    23401 aattgtgttc atagaggaca gggtcacgta tccgtgcttt cttttgataa gaccttgatt
    23461 ttctaagaaa attaaatcac gacgtaaggt acttgtgctg gagaaagtga tttctgccag
    23521 ctcttttacg gcaattcttt ttttcttttt gatgatttca atcaattcaa gtacacgttc
    23581 atcttttatc ataagctcct cctaatttat catttcaact atattatagc acaaattgga
    23641 ggaatttgaa ttatttttat gaatattggg ttaacatttg aacattattc aagtaagcgt
    23701 tcacatattg aaaaaataaa acgtggggat tataataaag ttaatcaagg acgaagagag
    23761 aagaaaaatg gaagcggttt tagcaataga tttaggtgcg acttctggaa gagcaatcgt
    23821 tggttacctt tctgaaaata aactagtaat ggaagaaata aatcgctttt ctaatctacc
    23881 tattagagta aaagggcatt tatcttggga tattgacttt ctactagcta aaattcttga
    23941 aagtatccgc ttggctaata ctagttacaa gattttatct atcggtattg acacatgggg
    24001 agttgatttt ggactggttg ataatgaagg taagctgtta ttacaacctg ttcattatcg
    24061 tgatgaaaga acaaagggag tgttaaagga aatatctgaa atgactgaat tagaaaaact
    24121 gtattcagag acaggaaatc agattatgga gataaatacc ttgtttcaac tctttaaggc
    24181 acgtcaagaa tctcctgact ctttctataa gaccaataag attcttttaa tgccagattt
    24241 gtttaattat ctcttgacag gtaagtttgc tacagaaaaa agcattgctt caacaactca
    24301 attatttgat cctaggagtc aaaactggaa tcagaatatc ttaaaactat ttgaattgga
    24361 ttcatcttta cttcctgaga ttgtttcaga gggaaatgtt cttggaagga taaaaaagga
    24421 gtatggttta ggcgatattc ctgttgtgaa tgtttgtagt catgatacag caagcgcgat
    24481 tgtctcagta cctaagacag aaggtagttt atttatttca tcaggtactt ggtctttggt
    24541 tggagtggaa cttacttcac cgcttcttac taccgaatcc ttcagttatg gatttacaaa
    24601 tgaagtcggt aaagatggag tgattacatt tctgaagaat tgtacagggt tgtggatcat
    24661 agaggaacta agacgttcat ttgaacgaag agggaaagcc tattcttttg atgatattag
    24721 gacaatggtg gagaaagaaa aagaaaatct tcctctgatt gatactgaat caactgaatt
    24781 tgcaacagaa tctgatatgc acaagacttt gacagaatat ctagcttatc atcatgaaac
    24841 tagagagtgg acagatggac aactatttaa gattgtttat gaaagcctag ctgaaacgta
    24901 taggaaagcg atagagttac tagaagaact aactcataag gtttataaga ggatatatgt
    24961 gattggagga ggtgctagag ccagttactt taaccaaatg attgctgata gaactggtaa
    25021 agaggttctt acaggtttga ctgaggctac agctgtgggg aatattgttg tgcagctcat
    25081 agctatggga caattaaaag ggatggaaga agctcaccat gttattgagg agtttctaca
    25141 attagagagt tattactccc aaaagaatta aaaagattga gagtttgtaa atttgcctcc
    25201 ctcccccttc ttaagttttg tacaagaagg ggggataatt ggtgaattga aaaatattta
    25261 gtgttttgat atgaggagga caagaatgtc agatgtaaaa caagaattaa ttaagtatgg
    25321 caagaagcta gtagaaacag atttgacgaa aggaacaggt gggaatctca gtgttttcga
    25381 tcgtgaaaaa caattgatgg caattacccc gtcgggtatt gatttctttg aaatcaaaga
    25441 atccgatatt gtagtgatgg atattaatgg aaatgttgta gagggagaac gcttgccatc
    25501 tagcgaatgg tatatgcatt tgattcaata tcaaactcgt gatgatatcg atgcaattat
    25561 ccatgctcat acaacttatg caacagtatt agcttgtctc agagaaccac ttccggctag
    25621 tcattatatg attgcagtgg cagggaaaga tgttcgggta gctgagtatg caacatatgg
    25681 tacgaaagaa ttggctgtga atgcagctaa agcaatggaa ggtcgtagag cagttttact
    25741 agcgaatcat ggaattttag caggtgcaca aaatttattg aatgcattta atattgttga
    25801 agaagttgaa tattgtgcaa aaatttattg tttagctaag aattttggag agccagtagt
    25861 tcttcctgat gaggagatgg atttaatggc agaaaaattt aaaacatacg gtcagagaaa
    25921 atagggagga tattaatgtt aaaacatata ccgaaaaata tttctccaga tttattgaag
    25981 actttaatgg aaatgggaca tggagatgaa atagtattag ctgacgcgaa ttatccttct
    26041 gcctcatgtg caaataagct aattcgttgt gatggcgtaa atattccaga attattagat
    26101 tccattctgt atttaatgcc attagatagt tacgtcgata gttcaattca gtttatgaac
    26161 gttgtttcgg gtgatgatat tcctaagata tggggtacct atagacagat gattgaaggt
    26221 catggtacag atcttaaaac gattacttat cttagaagag aagactttta tgaacgtagt
    26281 aagaaagctt atgctattgt tgctacagga gaaacttcac tttatgctaa tattatcctt
    26341 aagaaaggag tagttgttga aagagaaaat gtttaataga ggaattttag ttgccagtca
    26401 tggtaatttt gctagcggag ctctcatgac cgcagaaatg tttgttggtg agacaacaaa
    26461 tgatagagtt aggacattag gtttgatgcc tggagagaat attgtagagt ttgaacatta
    26521 ttttaaaaat caagtaaatg aactgttaga ctcaaatcaa gaggttatcg ttttgactga
    26581 cttgattgga ggaagtccta ataatgtggc tttgtcacgg tttttaaatt tggattcagt
    26641 tgatattgta acagggttta atatccctct cctagtggaa ttaatatcaa gttatgattc
    26701 aaaaatcaat ttagaagaaa ttgttcaaaa tgctcaaaat agtttgttta atgttaaaca
    26761 acaacttaac gtagaggagg aagaggattt atgtctatag agtttgttcg tattgatgac
    26821 cgtctggtac atggtcaagt tgtcactacg tggctaaaaa agtatgatat tgagcaagtt
    26881 atcattgtta atgatcgcat ctcagaagat aaaacacgac aatctatttt aaagatttct
    26941 gcaccggtag gtttaaaaat tgttttcttt agtgtaaaac ggtttgtgga agttttaaac
    27001 tctgtgccaa taaaaaagag aacaatgctg atatatacaa atccaaaaga tgtgtatgat
    27061 tctattgaag gaaatttaaa attggagtac ctcaatgtag gacagatgag taaaacggag
    27121 gaaaatgaaa aggtaacggg aggtgtagct ctaggtgaag aagacaaata ttattttaag
    27181 aaaatagttg ataagggaac gagagttgaa attcaaatgg ttcctaatga taaagttaca
    27241 atgttggaaa aatttttata aaaataattt aaggaggtac agtatatgct attcacacaa
    27301 gcattactgg tgacattagt tgggattatt gccactattg actataatgg accgttattt
    27361 atgattcacc gtccgttagt tacaagtgca atggttggct tagtcttagg agatttcacc
    27421 caaggtgttc ttattggttc agctcttgaa ttaacttggc tcggtgtaac aggtattgga
    27481 ggttacactc caccagatac tatttcaggt gcgattattg gtactgcatt tggtatttta
    27541 tctggtcaag gagaaactgc tggtatcgct atagcagttc caattgcagt tgctacccaa
    27601 cagttggatg ttcttgcaaa aactttagat gtttattttg tgaaaaaagc tgataatgat
    27661 gctaaaaacg gagattattc aaagatcggt ttttatcatt attcaagttt ggttttaatc
    27721 acgttattta aaattgtacc aattttccta gctattatgc ttggagggga atatgtggca
    27781 gacttgtttg ctaaggttcc accaatcgtt atgcagggac ttaactctgc aggtgcttta
    27841 ctaccttcaa ttggttttgg tatgctttta aatatgatgc tcaagaaaaa tatgtgggta
    27901 ttcttgttga ttggattcat ttgttctgtg tatggaggaa tgtcaaccat tgggatctca
    27961 ctagttggta ttgcggtagc atacttctac gatatgattg gaagtaaacc acaagaaaca
    28021 acttcaagta gtgatgttga ggaggatctt gatctatgat gaataataaa gtaactaaag
    28081 ttgaacttaa aaaagttttc aaacgaagtt ttatgtatgg ttcttcatgg aactatgaga
    28141 gaatgcagaa cctaggtttt ctatatacaa ttcttccagt attgaaaaaa ctatacccag
    28201 acaaagattc agcttctcct gcaatgaaac gtcaccttga gtttttcaat actcatcaaa
    28261 cagcggcacc atttattctt ggagttactt ccgctatgga agaacaagaa ggaaatgaag
    28321 gtgcagcttc aattactggt attaaagttg gcttgatggg gccactggct ggtctaggag
    28381 atagtttgtt ctggctgaca ctagttccta tctgttttag tattggtgcg tcttattcta
    28441 aagacggcgg tgctttaggt atctttatcg ccttaatatt gtttaatatt attaatattc
    28501 ctgttaaata tttcggtttg aaatatgggt atactaaggg ttctagtctt atccaagaaa
    28561 ataatacaaa aggaacattg aatcgcgtta cgagtatggc gacagcatta gggctagtac
    28621 tagtgggtgg tttgattcca tcaatggttg gtattaattt tggattagaa tttaagcagg
    28681 gggaacttgt tatttctgtt caagaaatga ttacaaaatt aattccagga tttatcccta
    28741 tggctttgac tttattaatg tgtaaattaa ttagaaaagg aaagaatccg gttgtactaa
    28801 tctttagtgt tatggctatt ggagttatcc tagttgtttt aggaattttg aagtagtaga
    28861 aagtgtggag gtggtatttg ggatatcacc tccattttgg aagagaggta aagagtgaaa
    28921 ttatggtata agaaagctgc ctcaaattgg aatgaagcct tgccgattgg gaacggtcat
    28981 ttaggtggta tgatttatgg ttcagctaca aaagaatgta ttcaactaaa cgatgagact
    29041 atttggtata gaggaaagtc agatagaaat aatccagact cactattgca tcttaaaaaa
    29101 attcgggaat atcttttaga tggagaaatt cagaaagccg aagaattgat aaagttaaca
    29161 atgtttgcta ccccaagaga tcaaagccac tatgaattac ttggggaact ttacattgag
    29221 catatagata ttcagtcttg tgctctttca ttgtatgaaa gagagctaga tttagataca
    29281 gctatttcta atgttgtgtt tgagcctaat agttgtaatt tacaaataaa aagagaatat
    29341 tttacgagtt ttaataagaa tattttatgt tgccgtatag tgtcatcagt tcaaaacaca
    29401 ttaaatttaa acattaattt gggtagaaat aaacggttta atgatgaagt atctaaactg
    29461 gattcaagta caattttaat gtcggcctct gctggaggta gaaaaggtgt tcagtttaaa
    29521 gtagtatgtc attctaaggt tacggatggt gaagtaagtg tattgggaga gacaatagtt
    29581 attcggaatg ctacagaggt atttctttat ctcaaatcaa tgacggatta ttggggaaat
    29641 atagatattt cttctcttca gggagaattt agtagtattg attactttac agaaaaagat
    29701 gaacatgtaa aaaaatatca ggagcaattt aatagagttg attttaaact agactatagt
    29761 aaagattgtc ttagcattcc aacgaatcta cttcttgaaa acactaaaaa gtatagtaac
    29821 tacttgacta acttgttatt tcattatgga agatatctgt taatatcgtc tagtcaaccg
    29881 aatggtttac ctgccaatct tcaaggaata tggtgtgatg aattaaatcc aatttggggt
    29941 tctaaatata cgattaatat taatactcaa atgaattatt ggatggtagg tccatgtgat
    30001 ttaccagaag tagaatatcc attatttgat atgctcgaaa gaatgagaga accgggaaga
    30061 ctaaccgcta agaaaatgta tggagctaga ggttttacag cacatcataa tacggatggt
    30121 tttggcgata cggctcccca atctcatgcc atgggggctg caatttgggt attaactatt
    30181 ccatggttat gtactcatat ttgggaacac tatttatatt tccaagatga gcgtattctt
    30241 acggaacatt ttgaaatgat aaaagaagca tttcttttct ttgaagatta tttatttgag
    30301 gtggatggct acttgatgac aggtccaagt gtctcaccgg aaaataaata tcgcttaaaa
    30361 aatggtattg aaggaaatgc ttgtctatca tctacaattg ataatcaaat tctaagatat
    30421 ttttgtgatt catgcattgg cattgcaaaa caattaggag acaattcgga ttttattagt
    30481 cgtgtgaagg agttaaaaaa gaaactacct aaaacaaaaa taggtagtaa tgggcaaatc
    30541 caagaatggt tagaagatta tgaagaagta gagcctgggc atagacacat ttcacctcta
    30601 tttgggcttt atccttataa tgagattgat attcataaaa ctccggaatt agcagaagca
    30661 gctaaaatca ctatcaatag gagattatca aacgctaatt ttttatcttc acaggagagg
    30721 gagcaagcga ttaataattg gttagtaagt ggtttgcatg ctagtacaca aacaggttgg
    30781 agtgctgcat ggctgattca tttttttgcg agactatatc aaggtgaacc tgcttataac
    30841 cagattaatg gtttgttaaa taatgcgact cttggcaatt tatttcttga ccatccacca
    30901 tttcaaattg atggtaattt aggtttggtg agtggaattt gtgaattatt agtacagagc
    30961 catcataatt ggttatcact aattccagct ttaccttctg cttggtcaga aggagaagtg
    31021 aaaggtttca gagtaagagg aggatataag gtatcgtttg cttggaaaaa tggggatata
    31081 acattcctaa aattggaagg aggaaacaaa gatcaaaaag taagagtaag aatatatggc
    31141 aaaaatactg atgtacaaaa tattgaattg gtatttaatt cagaaaaaat tattgagtta
    31201 aatttttagg tataagtcat gaataaagaa aaaataaaaa gaaaattaat cacaatattg
    31261 tttgtatgta ttgggatgtt atgttttgga ttgttagcag gagttaaggc tgataatcgt
    31321 gttcaaatga gaacgacgat taataatgaa tcgccattgt tgctttctcc gttgtatggc
    31381 aatgataatg gtaacggatt atggtggggg aacacattga agggagcatg ggaagctatt
    31441 cctgaagatg taaagccata tgcagcgatt gaacttcatc ctgcaaaagt ctgtaaacca
    31501 acaagttgta ttccacgaga tacgaaagaa ttgagagaat ggtatgtcaa gatgttggag
    31561 gaagctcaaa gtctaaacat tccagttttc ttggttatta tgtcggctgg agagcgtaat
    31621 acagttcctc cagagtggtt agatgaacaa ttccaaaagt atagtgtgtt aaaaggtgtt
    31681 ttaaatattg agaattattg gatttacaat aaccagttag ctccgcatag tgctaaatat
    31741 ttggaagttt gtgccaaata tggagcgcat tttatctggc atgatcatga aaaatggttc
    31801 tgggaaacta ttatgaatga tccgacattc tttgaagcga gtcaaaaata tcataaaaat
    31861 ttggtgttgg caactaaaaa tacgccaata agagatgatg cgggtacaga ttctatcgtt
    31921 agtggatttt ggttgagtgg cttatgtgat aactggggct catcaacaga tacatggaaa
    31981 tggtgggaaa aacattatac aaacacattt gaaactggaa gagctaggga tatgagatcc
    32041 tatgcatcgg aaccagaatc aatgattgct atggaaatga tgaatgtata tactggggga
    32101 ggcacagttt ataatttcga atgtgccgcg tatacattta tgacaaatga tgtaccaact
    32161 ccagcattta ctaaaggtat tattcctttc tttagacatg ctatacaaaa tccagctcca
    32221 agtaaggaag aagttgtaaa tagaacaaaa gctgtatttt ggaatggaga aggtaggatt
    32281 agttcattaa acggatttta tcaaggactt tattcgaatg atgaaacaat gcctttatat
    32341 aataatggga gatatcatat tcttcctgta atacatgaga aaattgataa ggaaaagatt
    32401 tcatctatat tccctaatgc aaaaattttg actaaaaata gtgaggaatt gtctagtaaa
    32461 gtcaactatt taaactcgct ttatccaaaa ctttatgaag gagatgggta tgctcagcgt
    32521 gtaggtaatt cctggtatat ttataatagt aatgctaata tcaataaaaa tcagcaagta
    32581 atgttgccta tgtatactaa taatacaaag tcgttatcgt tagatttgac gccacatact
    32641 tacgctgttg ttaaagaaaa tccaaataat ttacatattt tattgaataa ttacaggaca
    32701 gataagacag ctatgtgggc attatcagga aattttgatg catcaaaaag ttggaagaaa
    32761 gaagaattag agttagcgaa ctggataagc aaaaattatt ccatcaatcc tgtagataat
    32821 gactttagga caacaacact tacattaaaa gggcatactg gtcataaacc tcagataaat
    32881 ataagtggcg ataaaaatca ttatacttat acagaaaatt gggatgagaa tacccatgtt
    32941 tataccatta cggttaatca taatggaatg gtagagatgt ctataaatac tgaggggaca
    33001 ggtccagtct ctttcccaac accagataaa tttaatgatg gtaatttgaa tatagcatat
    33061 gcaaaaccaa caacacaaag ttctgtagat tacaatggag accctaatag agctgtggat
    33121 ggtaacagaa atggtaattt taactctggt ttggtaacac acactagggc agataatccc
    33181 tcttggtggg aagtcgattt gaaaaaaatg gataaagttg ggcttgttaa aatttataat
    33241 cgcacagatg ctgagactca acgtctatct aattttgatg tgattctata tgacaataat
    33301 agaaacgaag ttgctaagaa acatgttaat aatttgtcgg gtgaatctgt tagtctagat
    33361 ttcaaagaaa aaggagcaag gtatattaaa gttaaattac taacgagtgg agtgcctttg
    33421 agtttagcag aagtagaggt ttttagagaa tcagatggta agcaatctga agaggatata
    33481 gataaaataa cagaagataa agtagtctct acaaataagg tagctactca aagttcaacc
    33541 aattatgagg gtgtagctgc tttagcagtt gatggtaata aagatggaga ttacggacat
    33601 cattcggtga ctcatactaa ggcagattct aacgcttggt ggcaggtcga tctgggagaa
    33661 gagtttacgg tttctaaagt tgatatttat aatagaacag atgccgaacc tcagcgttta
    33721 tctaattttg atgttatttt tctatcttca tcaggagaag aagtttttag aagacatttt
    33781 gataaagtag ttgatggttt gttatcttta aaagtacctt ctgtaggggc taagctagtc
    33841 aaaatagaat taaaatcagc agctattccg ttaagtttag cggaagttga agtctatggt
    33901 tcaaagagaa ctccgaagaa actttctaat attgcattaa caaaagaaac tcgacagagt
    33961 tcaacggatt acaatggttt ttctcgtcta gcagttgatg gaaataaaaa cggagattat
    34021 ggtcatcatt cagtgactca taccaaagaa gattctcctt catggtggga gatagattta
    34081 gcacaaaccg aagaattaga aaagttaatt atttataata gaacagatgc tgaaattcag
    34141 agattatcaa attttgatat tattatatat gattcaaatg attatgaagt ttttacacaa
    34201 catattgaca gtttagaaag caataatcta tccatagact taaaaggact gaagggaaaa
    34261 aaggttagaa tttctttgag aaacgcagga attcctttaa gtttagcaga ggtagaggtt
    34321 tatacttata agtaatttta aaaattatca cccaggctac cgtaaatata atggagatgg
    34381 tagtatgaaa gaaacagaaa aataagagga aaatagtatg attcaacatc cacgtattgg
    34441 gattcgtccg actattgatg gtcgtcgtca aggtgtacgc gaatcacttg aagtgcaaac
    34501 aatgaacatg gctaaaagtg tggcagattt gatttcaagc acattgaaat atccagatgg
    34561 ggaacctgtg gaatgcgtga tttctccatc tactattggc cgtgtaccag aggctgcagc
    34621 ttcccatgag ttgtttaaaa aatcaaatgt ttgcgcaaca attacagtta caccatgctg
    34681 gtgttatggt agtgaaacta tggatatgtc tccagatatt cctcatgcta ttttgggatt
    34741 taatgggaca gaacgcccag gagctgtcta tcttgcagct gtactagctt cacatgctca
    34801 aaaagggatt ccagcctttg ggatttatgg aagagatgtt caggaagcta gtgacacaga
    34861 tattccagaa gatgtcaaag aaaaactttt acgctatgcg cgtgcagctc ttgcaactgg
    34921 cttgatgaga gacactgctt acctatcaat gggtagtgtt tcgatgggga ttggtggttc
    34981 tattgtaaat ccggatttct tccaagaata cctaggaatg cgaaatgaat cggtagatat
    35041 gacggagttc acgcgccgta tggaccgtag tatttacgac cctgaagagt tcgaacgtgc
    35101 gctcaaatgg gtgaaagaaa acgtaaaaga aggattcgac cataaccgtg aagaccttgt
    35161 tttaagccgt gaagaaaaag atagacaatg ggaatttgtt attaagatgt tcatgattgg
    35221 acgtgactta atggttggta acccaagact tgctgagctt ggttttgagg aagaagcagt
    35281 tggtcaccat gctttagtag ctggtttcca aggtcaacgc cagtggacag atcatttccc
    35341 aaatggggac tttatggaaa ctttcctcaa tactcagttt gactggaatg gtattcgaaa
    35401 accatttgta tttgcgacag agaatgattc actaaatggt gtgtctatgc tctttaatta
    35461 tctattaaca aatactccac aaatctttgc tgatgtgcgt acttattgga gcccagaggc
    35521 tgttaaacgt gtaacgggac atactttaga gggtcgtgct gcagctggct tcttacatct
    35581 aatcaactct ggttcttgta cattggatgg tacaggtcaa gctactcgag atggcaaacc
    35641 tgttatgaaa ccattctggg agttggaaga aagtgaagtg caggctatgc ttgaaaatac
    35701 agacttccca ccagcaaacc gcgaatactt ccgtggagga ggattctcaa ctcgtttctt
    35761 gacgaagggg gatatgccag taacaatggt acgtctcaat cttctaaaag gggttggtcc
    35821 agtgctacaa attgcagaag gttatacact tgaacttcct gaagatgttc accatacttt
    35881 agataatcgt acagatccag gatggccaac tacttggttt gctccacgtt tgacaggaaa
    35941 aggtgctttc aagtctgtct atgacgtcat gaataattgg ggagctaatc acggagccat
    36001 aacatatgga cacattggag cagacttgat taccttggct tctatgttga gaattcctgt
    36061 caatatgcat aatgtacctg aggaagatat ctttagacct aaaaattggt ccttatttgg
    36121 aacagaagat ctagaatcag cagactatcg tgcatgtcag ttgttgggac cactacataa
    36181 ataaaacttg tttatatagg aggtgaactt acgtccctcc tatcctttta aaaagatttg
    36241 ttaaacaatt cacaaataat tgaaaacgaa tacaaaaagt aatataatga tgttaaatag
    36301 atagcgcgga ggcgcaggag gaaaattata tggctacatt ttatgttccg gcagtcaacc
    36361 ttattggtaa aggtgttgta aatgaagtgg gtccttatat caaggaactt ggctataaaa
    36421 aggcactttt ggttacagat aagtacatcg aaggcagtga tattttgcct aaggttttaa
    36481 aaccactgga tacagaagga atcgaatatg tcatctttag cgatgtagag ccaaacccta
    36541 cttgtaaaaa tgtcacagat ggggtagctg ctttgcaaga acatggctgt gactttatca
    36601 tcagtcttgg cgggggttct ccacaggatg cagctagttg tatttctatc atggctacaa
    36661 atggtggaaa accacaggat tatgaagggc ttcataagtc tgctaaaaaa ggcttgccag
    36721 ttgtggctat caatacaacg gcaggaactt ctgcagaaat cactattaac tatgtgatta
    36781 ctgatgaaga acgcaaggtt aagatggtaa tggttgacaa gaatagcctt gctcttatct
    36841 ctgttaatga cccggaactc atgctttcca aacctaaagg cctgactgct gctactggta
    36901 tggatgctct gactcacgct gttgaagctt tggtaacacc tggtgcttat gatgtaacca
    36961 agaaactgtc tattggtgct attgagctta tcaaggaata tcttcctcgt gctgtagaaa
    37021 atggacatga tattgaagcg cgtgaaggta tggtcaatgc catcttcctt ggtggtatga
    37081 gctttaataa tgctggtctt ggttatgttc actcaatggc tcaccaactc ggtgcagtat
    37141 ataatttgcc acatggcgtg tgctgtgcca tgttgctacc agttatagaa cgtgaaaatg
    37201 ctaaacgtgt accagaagct ttccgcaatg ttgccaaagc cttgggactt catgtagaag
    37261 gtaaatcaga tcaagaatgt gccgattatg cgattgctga gattgagaag ctttctgaga
    37321 cagtaggtat tcctaagaaa ctgactgaac ttggtattga agaaaaagat ttcgactttg
    37381 aatacctttc taagaatgcc ttgattgatg cctgcgcacc aggaaatcca tttatgccaa
    37441 ccttagaaga aacgattgcc ttttataaag agttatttta gcaagagatt ggacgacaat
    37501 aggacaattc acctctaatt attgacattt caggaaaaat cgcagtaaaa acggcacagc
    37561 cttctttaaa tgtgctataa tactagaaaa atatttgtgg aggttccatt atggcaatat
    37621 ttttcatgat ttttctgatt gtttgtgtgc tcctattggt gatagtcaca ctgagtacag
    37681 tttatgtggt tcgtcagcag tcggtggcga ttattgaacg ctttgggaaa taccaaaagg
    37741 ttgctaatag cggtattcat attcgcttgc cttttgggat tgactcgatt gcagcacgga
    37801 ttcagttgcg cttgttgcaa agtgatattg tggttgagac taagaccaag gacaatgtgt
    37861 tcgttatgat gaatgtagcg actcagtacc gtgtcaacga gcagagcgtg acagatgctt
    37921 actataaact catacgtcca gaatctcaga ttaaatctta tatcgaagat gctcttcgct
    37981 cttctgttcc aaaattaacc ttggatgaat tgtttgagaa aaaagatgag attgcccttg
    38041 aggttcaaca ccaagtagca gaagaaatga ccacttacgg ctacattatc gtgaaaacct
    38101 tgattaccaa ggtcgaacca gatgcagaag ttaagcaatc catgaatgaa atcaatgcgg
    38161 cgcaacgtaa gcgggtcgca gcacaagaat tggcggaagc tgacaagatt aaaattgtca
    38221 ctgcagctga agcagaagca gaaaaagacc gccttcatgg tgtggggatt gcccaacaac
    38281 gtaaggcgat tgtggatgga ttggcagagt ctatcaccga actcaaggaa gccaatgttg
    38341 gcatgacaga agaacaaatc atgtctatcc tcttgaccaa ccagtatttg gataccttga
    38401 atacctttgc ctctaaagga aatcaaacca tctttttacc aaatactcca aatggtgtgg
    38461 atgatatccg aacacaaatc ttgtcagccc ttcgcgctga gaagaaataa tagactaata
    38521 ctcttcgaaa atctcttcaa accacgtcag cgtcgtcttg ccgtatagat gttactgact
    38581 tcgtcagttc tatctgcaac ctcaaaacag tgttttgagc aacctgtggc tagtttccta
    38641 gtttgctctt tgattttcat tgagtataaa gagcttggca acaggctctt tttgtattgc
    38701 gtttattaag aaaaacaaaa aacatcgata tacatttaac taaaaattat tgtatgtcat
    38761 ctcccttaat taggaatgat aagggaataa ctagaaagat ttgtgaatac aaactatttc
    38821 tgatatacaa aatatacagt aataatgaat gatgggagat gggatgaaag aatttcaatt
    38881 tgagagaaag cagcgttttt ctttgaggaa atatgcaata ggagcttgtt cggtcttgct
    38941 aggaacgagt ttattttttg ctggtatggg tgctcagcct gtacaggcta cagaaacgag
    39001 ttcagcacta atttcaagtc attatttgga tgagcaggat ttatctgaaa agctgaaatc
    39061 tgagttgcaa tggtttgaat tagaaaacaa gcttttgaac ttatgggagc attaggttac
    39121 tatgaaggat ttgttcctta tgtttcaaat caatacaaaa accaaactga agaagaaggc
    39181 aaaccgctat ctgataaata tattttcgaa aaaatcttag gaaaaacata tgcagccttc
    39241 aaaaaagatc aaattaatga gcgtgtcgag aaattaggta agttaaaacc tattacaata
    39301 aattacaacg gaaaatcaga agtaattgat agtaaagaaa aattacaaaa gcttatgaat
    39361 aaagccgtta aagacgaagt ggctcaaata tagtaaaatg aaataagaac aggacaaatc
    39421 gatcaggaca gtcaaatcga tttctaaaaa tgttttagaa ggagaggtgt actattctag
    39481 tttcaatata ctataaaatc aggcaatacc acggctaaaa agtttgagtt tatcgaaaca
    39541 ccagtgcaaa aactgaaaaa agcgatttat aaagctcatc tcaaagattc agatgacttt
    39601 agaccagaaa catccacacc aaatcttttt gaaagctgtt tgaagctttg tccttgcttt
    39661 cttagttcat agatctgaac tttatcttca taactcaatt tcataataaa acaccccaaa
    39721 agttagattt attctgtcta acttttgggg tgcagttcat taatcggtcg attttttttg
    39781 gtagaaacag ttgcctgatt aagttgcaag tcgatagacg gcttcggcat aaatatccat
    39841 agcacggtac aaatcttcta gaacggcaca ttcatttgcc tgatgttctg tctgcttcgc
    39901 tcctgggaat aaggcgccga aggctacaca atttggcatg gtgcgagcaa aagtggcacc
    39961 accggatgaa atagcaggac tgttatcgcc agtcttttct tggtagattt gcatcagtgt
    40021 gctaacgagt ttactgtctt ttgcgacgta tagaggcgct agatagtcaa actcttcgta
    40081 gcggagttgg tagttttgtg cacatcttgt aagcaactct actagttctt ccttatcagc
    40141 taagacagga gtccgaatgt caatacggat ttcagaacgt tcatgattga tcatgagacc
    40201 tgcgacatta aaggataggt gaccagaagg ttcatctgct atatcaccaa agatttgtct
    40261 tcctgtgccg tcttgacctg cttgtgttgc aagaaaactg agagcagggt gttcttggag
    40321 aggagcaaga atggtagcta gtcggatgac agcattgata ccttgactag catccttagc
    40381 atgctttggc actccgagaa ccgttacggt ttgttcagtg gattggtaat cataaccagc
    40441 ttctttgaga ccgttacaaa cctgttcata gaggggacct tggtagttgg ccttgtctgg
    40501 tacaacgtta aaggcgcctc ctacttcaag ctctagttga tccgatccag ggccatgaag
    40561 tttgacctgt agaagccctt tttcagcata ggtcagagga aaagatgagt caggtgcaaa
    40621 gcccatgctg gcctgttctt cgatggtatt gtagcgtgcc atgcagcgcc agagggtttc
    40681 ctcatcggta ccaaagataa agcgtacgcg ctttttgaac tgaatacctt ggtccagcaa
    40741 gctttttact gcatagagag ctgcgagcga agggccttta tcatcttgga caccacgtcc
    40801 gaatacccag ccgtctttga tagttgcttc aaatggcggt gtctgccaat ctgcttcatc
    40861 acctgatgga acaacatcca aatgacagag aatggccaga agctctgctc cctgaccgat
    40921 ttctgcatat ccgtaataac ctttagggtc aagataggta gtgaaaccta tgtcttgaca
    40981 aatctctaaa gttttttcta ggacatcttg gattgcttgt ccaaaaggtg ttccattttc
    41041 tccttcattg agtactgaag gataggaaat caaggttttt aatgatataa gaaattcatc
    41101 tttaacttga tttgttatat ctattttcat ggaatcacct cactcactat tttataggaa
    41161 tggaaggaag gttccaagga gaagaagggc gatggtcact acaataatag cgactacgag
    41221 tttgcccatg aatttccacc aagtaccaat gttgatacgt ccaagtgcaa gagctcccat
    41281 cacaatacca gatgttggtg caatcaagtt caagacacct gaagcagatt ggtaagcagt
    41341 gataatcaag ctaggacgga catttacaaa ttctccaagt ggagccatga tacccatagt
    41401 tgcgctggca agaccagatg aagatgggat caagaatgac ataggtagat agaagatata
    41461 agttacaacg ataaagactt gtgaagatag accgctcaag ccttctttac cccagttgag
    41521 gattgtatcg gtaatcatac cgtcgttcat gataacttga ataccacgag caatcgctac
    41581 gatcaaggca acactgagca agtcagcagc accattcatg aaggaagaga taatcttatc
    41641 ttctttaaga ccataaataa caccaatcag gatacccata aaggcaaaga gcattgcgcc
    41701 ttctgggaag taccaagtac ctagtgcaga agtagatgaa ccgacaatat taccaataac
    41761 tggaagacca gtcaaccaag cattaaagtc atcaaaaatg gtaacgccaa ggtctgtcca
    41821 tggaatgaag ctcaatacca tcaagatgaa tgtcaacaca aataagaaga gaactgattt
    41881 ttgtttgctg ctaagtgtag attctacaga tgaagattct tccacgttaa agtgtttcaa
    41941 atcttctttg cgagtactat aaaccagtga cttagtcgga tctttttgaa tcttatccgc
    42001 ataacggtaa acaaaccaag tactaagagc agtcaaggta acccagaaga tcagacgaag
    42061 tacgataccg tcccctgtac caactcccgc agtcgctgaa gcaatacctg tcgcaaatgg
    42121 attcagagta gatgccaaac agccgatttg agaaccgagc aaaataattg caacaccagt
    42181 caggctatca aaaccaacgg ccatcataac tggcacaagg agtggataga aagccattgt
    42241 ttcttcaccc ataccataag ttgtaccacc gagggcaaac aaaggcatca gtaccaaaat
    42301 taacattttt tcgcggccct tatacttctt cacgatagag gcaatcccta cgtcaagagc
    42361 accagttttg ttgacaatgc caaggaaacc accaaccata aggatgaaga aggctacatc
    42421 aatcgctgcg ctcgtttctt taatgagcga accttcctct ggatgagtac ctagcatagc
    42481 ccgaatcggt gccatgagga catcccaaat cccttgtgga ttttgaggct gagtctcgta
    42541 aataccttct ataaaggccc ccgcagggat aaaccaagtt agcactgcca taatagcaat
    42601 gattatcaat aatacggtgt aagatgaagg catcttaaac ccttttttag ctttttcact
    42661 catttgtttt tcctcctgat gtctaacaaa gtgtaaaaaa ccaactactt tcttaaataa
    42721 acatttaaga aaacgctttc tatttatatt tgttttacca tattaaagtc taaaaaacta
    42781 atatcttttg aaatattgta catgttttca agaataattt ctaatttgat ataaagatac
    42841 tagaaataga atacatctta ttagtaaaac aacttatcct ttttcaataa ttgttccact
    42901 ttcagattca atcaaggcgc ctagattttc aagggaagta ataactgctt ttccttctgg
    42961 acgaccattg acaaaagcga tagctgcttc tacttttgga agcatgctac ctggtgcaaa
    43021 ctgatcttgt ttgatatatt cttccagctg ggcaacattc acatgttcca atttttcctg
    43081 gtttggcttg ttgtagttaa caaatacata atctacacct gtcaaaatga tgaagaggtc
    43141 tgcatcaacc aattctgcca aacgttggga agcgaagtct ttatcaataa ccgcttcgac
    43201 accagtcaaa tgtccattgt tttctttgac gacgggaata ccgccaccac ctgcagctac
    43261 gacgacttga ccattattta aaagagtacg gatggtttca atttctttga tgtcaacagg
    43321 ttttggtgag gcaacgacct tacgccagcc acggccagca tcttccttga aagtcgctcc
    43381 gcttttttcg gcttctgctt ttgcttcttc ttctgaatag aaaggaccga ttggtttact
    43441 caagttaaca aaagctggat catttttatc tacgacaact tgcgttacaa cagaggcaac
    43501 atttttttcg atgccttcat ccaagagagc attttgcaaa gcatttttca accagaaacc
    43561 gatgctacct tctgtcatag cgacaagtga gtcgagtggg aaggcagggt tcttttcaga
    43621 gtctgatgcc aaatgttgga gcaagagatt cccaacttga ggtccattac cgtgagtgat
    43681 aatcaaatca tctccatttt taatcaattt tacaagatgc ttagctgttt caactaaagc
    43741 ttcttgttga gcctttgctg atgggtcaga agaaagaatc gcatttcctc ccaaagctac
    43801 tacaatttta cgatttgcca taaattctcc tttatcacac tcaatagaat gcgtttagat
    43861 ttcaatttaa tgatttttca catattttat aagaaataat agattaccat tacataaaag
    43921 aggaccggac taaagctatt agtcgcagcc ctcatagctg ttggtagacg gtttattatc
    43981 taaaattata ctttaggaat ataaaggtta ccaagtgtcg cagccataac agctttgata
    44041 gtgtgcatac ggttttctgc ttgatcgaag tggcgagcgt acttgctgcg gaagacttcg
    44101 tctgttactt ccatttcttc tacaccaaat ttttcagcaa cgtctttacc ataaacagtg
    44161 tgagtatcgt ggaatgctgg caagcagtgt aggaagatca agttttcatt gcctgctttt
    44221 ttaactaagt ccatattgac ttggtaaggt ttaagaagag ctacacgttc tgcgaatttg
    44281 tcttcttcac ccattgatac ccaaacgtct gtgtaaagaa cgtctgcatc tttaactgct
    44341 tcatcagcat cttcagtgat gagaacatgt gcgccacttt ctttagcaaa tccttctgcc
    44401 aattcaacga tttctttttc tgggaagagt tcttttggtg agaagatgtg aacattgaca
    44461 ccaaggatag cacctgttac gagcaagctg ttggcaacgt tgttacgtcc atcaccacag
    44521 tataccaatg tcaagccttc caagcgaccg aagttttctt gaacagtcaa gtagtcagcg
    44581 agcatttgag ttgggtgcca ttcgtcagtt agaccgttcc atactggaac gcctgagaat
    44641 tctgccaatt cttcaaccat acgttggctg aatccgcgga attcaatccc gtcaaacata
    44701 cgtcccaata ctttagcagt atcttcagta gattcttttt tacccaactg aatatcattt
    44761 gctccgaggt attctgggtg agcaccaagg tcgatagccg cagttgtaaa ggctgcacga
    44821 gtacgagtag atgttttttc aaataggaga gcgatattct tgccagcaag gtagtggtgt
    44881 tgaatattgc gttttttcaa atctttcaag tgagctgaaa gaccaataag gtattctaac
    44941 tctgcacggg taaagtcttt ttctgctaag aagctgcgtc cttggaatac tgaatttgtc
    45001 attttattat ttcctctttc tattttttac attttctatt gacgaatatc gaacagcgat
    45061 tacacttctt cacgttcaaa tggcatagac atacaacgag gtccaccacg cccccgaacc
    45121 aattcacttc cgcgaatctt aatcaagcga agcccgtatt cttccaaaat cttattggtc
    45181 acggtattgc ggtcataaac aactaccaca ccaggtgcga tggtcaaagt gttagaaccg
    45241 tcgttccatt gttcacgcgc agctgctacg atattgccac caccgcaacg aatcaaatga
    45301 actttttcta catcaaggtt ttgagcaaga agttcagcta agtcaccttt ctcttcaacg
    45361 attttaagtt tttcgttttc gtaagtaact gagtaaacgt gaaggtcgcc ttcgatttct
    45421 gggtgaatag tgaacttgtc atagtctacc atagtgaaga cagtatccaa gtgcatgaat
    45481 ttacggttgt tagcaaattc aaaggccaaa actttcttga agccaacatt tttcttgaag
    45541 atgttgacca aaagtttttc tatagaagct gcgtctgtac gttgagagat acctactgca
    45601 aggacgtctt tagaaagaac tagctcgtct ccaccttcga tacgcgtatc ttcttcacgg
    45661 ttgtagacca aatccacttt tcctccatag attgggtggt atttgaagat atacttaccg
    45721 tagagtgttt cacggttacg agtgtctgca aacatgtggt taagcgatac ggcgtttcca
    45781 attgttgcaa atgggtcgcg agtgaaatag aggtttggca tcgggtcaat tgcaaatgga
    45841 taatctgatt caactaagtc agttagatct ttagcttcgt caggaatttc tggcaattca
    45901 actttttgaa tcccagccat tgttttttca accaattctt ggttgtcctt gatgccgtga
    45961 agcaattcac gaatagcaac cttggtttga cgatcacgga tgttggcttc gtctaagtat
    46021 tcctcgataa attgatcgcg gatttctgga gaggtcaatg attcagcagc gagttgttct
    46081 aggtagagaa cctcaattcc ttcatcgcga agagcttggg caaatgcatc atgttctttt
    46141 tgagcatctt ccaagaaagg aatatcatca aaaagaagcc tttcaagata gtccggcaac
    46201 aagttttcta actccttgcc tggacggtgt aacataactt ttttcagttt cccaatttct
    46261 gagaagacct gaattggatg tgaagacatg tattttcctc cttaaaaatt ttgacttggc
    46321 accattttgg gtaccgctta catgtatgtt ataacgcaat tcctaggtaa tgtcaatggc
    46381 tataatttct cggaaaataa tataaattat gatatttagc acaattttat gttattatac
    46441 acaacatagg atggaataca tatatacaaa tgcataaact tctattaaag aggatataaa
    46501 atttttttaa aaaatttttc aaaaaataca caaataacca aaaagtgtcc aattatcatc
    46561 tggttatcac ttggatctgt ataaagagaa atgtttgtgt gaaaggataa aaagatgcaa
    46621 cattcttttg aagatagatt ttggagaagc atttcttgct caattgtaca aattatagaa
    46681 tcttttctga gtatttagga agagataatt atcttattga ccctcttttt attttttgtt
    46741 atagtcgacg agatgatagt ttagaataat cacttattca caatctgtgg aaaagtctgg
    46801 agagtgaatg gtcttcacac aatgacctga aagaagcctg agaataatta tggagagtag
    46861 cattctgaga ggtgttagca gaaccatatg acagagctgt ttgaagaggg aacattgagg
    46921 agcaaaatcc tgagcctacc agttggagtt ggaaagagct ggcggttaga tcatttttta
    46981 ttatccacaa cctgtggata accttgtgaa caagagaagt tgctaaagaa ggagatatat
    47041 aacgatgaag aaaatcaaac cgcatggacc gttaccaagt cagactcagc tagcttatct
    47101 gggagatgaa ctagcagctt ttatccactt cggtcctaat accttttatg accaagaatg
    47161 ggggactgga caggaggatc ctgagcgctt taacccgagt cagttggatg cgcgtgagtg
    47221 ggttcgtgtg ctcaaggaaa cgggcttcaa aaagttgatt ttggtggtca agcaccacga
    47281 tggctttgtc ctttatccga cagctcacac agattattcg gttaaggtca gtccttggag
    47341 gagaggaaag ggcgacttgc tccttgaagt atcccaagct gccacagagt ttgatatgga
    47401 tatgggggtc tacctgtcac cgtgggatgc ccatagtccc ctctatcatg tggaccgaga
    47461 agcggactac aatgcctatt atctggctca gttgaaggaa atcttatcaa atcctaacta
    47521 tgggaatgct ggtaagttcg ctgaggtttg gatggatggt gccagaggag agggcgcgca
    47581 aaaggttaat tatgaatttg aaaaatggtt tgaaaccatt cgtgacctgc agggcgattg
    47641 cttgattttt tcaacagaag gcaccagtat ccgctggatt ggcaatgaac gagggtatgc
    47701 aggtgatcca ctgtggcaaa aggtgaatcc tgataaacta ggaacagaag cagagctgaa
    47761 ctatcttcag cacggggatc cctcgggcac gattttttca atcggagagg cagatgtttc
    47821 catccgtcca ggttggttct accatgagga tcaggatcct aagtctctcg aggagttggt
    47881 cgaaatctac tttcactcag tagggcgagg aactccactc ttgcttaata ttccgccgaa
    47941 tcaagctggg ctctttgatg caaaggatat tgaacgactt tatgaatttg cgacctatcg
    48001 caatgagctc tataaagaag atttggctct gggagctgag gtatctggtc cagctctttc
    48061 cgcagacttt gcttgtcgcc atttgacaga cggccttgag accagctctt gggcaaacga
    48121 tgcagacttg cccatccagt tagaactcga cttaggttct cctaaaactt ttgatgtaat
    48181 tgagttgaga gaagatttga agttaggcca acgtatttct gctttccatg tgcaagtaga
    48241 ggtggatggt gtctggcagg aatttggcag gggcttcaca gttggtcata agcgcctctt
    48301 gcgaggtccg ctagtagagg cacagaaggt gcgcgtgatg attactgaag cacaatctat
    48361 gcctctactg accaagattt ccctttataa aactcctgga ttatcaaaaa aagaagttgt
    48421 tcaggaacta gcatttgcag aaaaaagcct agctgtggca aagggagaga ctcttcattt
    48481 taggattgaa cgtagtgaaa gtagctcctc tttagaggct aagatttcga ttcaaccggg
    48541 gacaggtgtc catggtgtcg cctatcagga tgagattcaa gttcttcaat tccaagcagg
    48601 ggaaagcaaa aaagatttgc atctaccaac cctgtatttc gcaggagata aaaccttgga
    48661 tttctatctg aacctaacgg tggatggtca gcttgtggat caacttcaag tccaagtttc
    48721 ataaaagaag aacctttgcg cgatgcaaag gttcttttgg ttattaatga cttggtaacc
    48781 agctgagggt gaaagttagt tgttcagctt ttaagaggtc ttggtgttga atagttgata
    48841 cgagtgtttt gtccagtcgg cattctttga caaagttaaa atggttgtgg ttttgtttag
    48901 tatggatatc cagccattta tcttctttag cgaggtagac tcgtagatgg tcaaagagag
    48961 agattccgag gtcatagctt ggttttcctg gacaggttgg ataaaatccg agagctgacc
    49021 agatgtacca agcagagaga ctaccattgt cttcatctcc aggataggct tcccaacttg
    49081 ggtgaaaagc tttctgacgg agcgtcttga taagaagggc agtgtagtca gggtaatcgc
    49141 tgtaacggaa gagataagga atgtggaaac taggctggtt ggaaatggct atctgtccaa
    49201 aaggagcagt agccatctcg ctcatttcgt gaatttcgta accatagcct gttgtttcaa
    49261 agaggggagc atcttgacag gctttcaaaa gatagttgct aaaggtttct tttccaccca
    49321 tcagttggat taagccaggg atgtcgtgga gaacgcctaa agtagcttga atggcagagc
    49381 attcagcgta gtctcgcccc caactataag gagagaagtc agggtgaaag tttccttgat
    49441 tgtctcgtgc tcgcatgtaa cctgtctcag cgtcaaatag ctggcggtaa ttttgtgaag
    49501 cagccttgta ggtttcagcg atttctatgt tttttagttt tttggcacag ttggcgatac
    49561 aaaagtcact ataggcatag tctagagtat ggctaacact ttcgtggtgg tcggtagaga
    49621 ggtaacctag ttcttggtat tgggctagtc cgtggcggcc attgatgccg agagggtcgg
    49681 ctttgctggc tgttttgagc atggcttgga agagttctcc ttctaggtcg ggggccatgt
    49741 ccttgcaggc gctatctgcg ataataccgt ctaaaagtgt acctggcatc ataccccgtt
    49801 catctggagc cagccatttt ggaaggaaac cagtatcgcg gtagctattg aggaaacctt
    49861 ctaaaaagcg ttgatagtgc tccggtatga taagggcaaa gagggggaag gtggtgcgga
    49921 aggtatccca gaaaccattg ttgctaaaga ggacaccagg cttgacagta ccagtagcca
    49981 gatccatgtg gatggcttgc cctgactcat caacctcata aaaagtctgt gggaagagga
    50041 agagtctgta gaggcagtgg tcaaagaagg ttcggtcagc ctctcctgtc tctataatgt
    50101 caaaacgatg gaggagattt tcccaatccg cttgggcact tgttttacag ctatcaaaat
    50161 cttcttgagg tagattgatt agagcttgag aaggagagat gaaagaagtg gctagttgca
    50221 tctcggtttg actacttgct aagtcaattc gccagtctcc agcttcttgg ctgatagcaa
    50281 gaatatccgt gttcatttgc agggcagtga acatcgttag cgaatttttg ttagtttcag
    50341 ttttaccttc ttgttgcagg gcaagagttc gcttatctac ttgctctact gtcagttcat
    50401 ctgttgcgtg aagatagagg gagagggctt tgccttgctt ttgcttcaaa cgaatagaag
    50461 caccgtagca agtcggtgtg agctgggttt caatctgata gcgcagggag aaaatcttta
    50521 gataatgagg ttggaaagag gccttatccc tatcatagga agattggcgg tgaaagaggc
    50581 tgtctccacc cagttgactg gtgacaggtg tcagaaggag ccaagagtag tccccaatcc
    50641 aaggactggg ctggtgagtt aatcgaatcc cctgaaagat aggcagatgt ggatcaaaaa
    50701 accaagatcc atcctggtca ctggtctggg gcacaaagta attcatccca aaaggcacgc
    50761 ctgtgtatgg cagggtattt ccccgagaaa aggcatgctt gttggtagtt ccaaagcggg
    50821 tatcgatggt ttcaagtagt ggtttcatag tctttccttt agctgttttt ctacattata
    50881 tcagaaaaag agggccttta gaaaaggagt ttcaaaaata actattttgt agaaaaatga
    50941 ctatcatttg tgtatgtatt ttctgtctca aaagctatat actgaacatg aaacttgttt
    51001 gaaagaggta aaatttaaaa tggtttattc gaaagaaatc gtcagagagt ggctagatga
    51061 agtagcagag cgggctaagg actatccaga gtgggtggat gttttcgagc gttgctacac
    51121 cgataccttg gacaatacgg ttgaaatctt agaagatggt tcaacttttg tcttgactgg
    51181 ggatattcct gccatgtggc ttcgagattc gacagcccaa ctcagaccct accttcatgt
    51241 agctaaaaga gatgccctcc tgcgtcagac cattgcaggt ttggtcaaac gtcagatgac
    51301 cttggtactc aaggatccct atgctaactc cttcaacatt gaggagaact ggaaagggca
    51361 ccacgagact gaccacacag accttaacgg ctggatctgg gagcgcaagt atgaggtgga
    51421 ttcgctttgc tatcctttgc agttggctta tctcctctgg aaagagactg gcgagactag
    51481 tcagtttgat gagatttttg tcgcagcgac taaggaaatt ctccatctgt ggacggtgga
    51541 acaagaccac aagaactctc cttatcgttt tgtccgagat acggaccgta aggaagacac
    51601 cttggtaaat gatggctttg gacctgactt tgcagtgaca ggtatgactt ggtcagcttt
    51661 tcgtccgagt gatgactgtt gccagtatag ttacttgatt ccgtcaaata tgtttgctgt
    51721 agtagtcttg ggttatgtgc aagaaatctt cgcagcatta aacctagctg atagccagag
    51781 tgttattgct gatgccaagc gtcttcagga tgaaatccaa gaaggaatca aaaactacgc
    51841 ttacaccacc aacagcaagg gcgaaaagat ttacgctttt gaagtggatg gcctaggaaa
    51901 tgccagcatc atggatgatc caaatgtacc aagtctacta gctgcgccct atctgggcta
    51961 ctgttcggtc gatgatgaag tgtatcaagc tactcgtcgt accattttga gctctgaaaa
    52021 tccatacttc taccaaggag aatacgcaag cggtctcggc agttctcata ccttctatcg
    52081 ctatatctgg ctaatcgccc tttctatcca aggcttgaca acaagagata aggcagagaa
    52141 aaaattcttg ctggatcagc tggttgcctg cgatggtggt acaggtgtca tgcacgaaag
    52201 ctttcatgta gatgatccga ccctctactc tcgtgaatgg ttctcctggg ctaacatgat
    52261 gttctgtgag ttggtcttgg attacttgga tattcgctaa ggggctcgct ttagctcaac
    52321 cgattcttat cagaatcaca agtttacatt taaaacgtta aaatttaaat ttagaatgag
    52381 gttttacttc atggaaaatg ttgttgtaca tattatctca catagtcact gggaccgtga
    52441 gtggtacttg ccttttgaaa gtcatcgtat gcagttggtg gaattgtttg acaatctctt
    52501 tgatctcttt gaaaatgacc ctgagttcaa gagtttccac ttggatggac aaactattgt
    52561 ccttgacgac tacttacaaa ttcgccctga aaatcgtgac aaggtccaac gctacattga
    52621 cgagggcaag cttaaaattg gtccctttta catcttgcag gatgattatt tgatctccag
    52681 tgaagccaat gtccgcaata ccttgattgg tcaacaagaa gctgccaaat ggggtaaatc
    52741 aacccagatt ggctactttc cagatacctt tggaaatatg ggacaagcgc ctcaaattct
    52801 tcaaaaatca ggcattcacg tggcgacctt tggtcgtggt gtgaagccga ttggatttga
    52861 caaccaagtc cttgaagatg agcagtttac atcccagttt tcagaaatgt actggcaggg
    52921 tgtggatggt agtcgtgttt taggtattct ctttgccaac tggtacagta acgggaatga
    52981 aattccagtt gacaaagatg aggccttgac cttctggaaa caaaaattgt cagatgtgcg
    53041 tgcctacgct tcgaccaacc aatggttgat gatgaacggc tgtgaccacc agcctgtaca
    53101 gaaaaatctg agcgaagcca ttcgtgtggc aaatgaactc ttcccggatg taatctttgt
    53161 tcatagttcc tttgatgaat atgttcaagc tgtagaaggt gcgcttcctg aacacttatc
    53221 aactgttaca ggtgagttga ccagtcagga aacagatggc tggtacacac ttgccaacac
    53281 ttcttcatcc cgcatttacc taaaacaagc cttccaagaa aatagcaacc tcctagagca
    53341 agtggtagaa cccttgacta ttatcactgg tggacacaac cacaaggacc agttgaccta
    53401 tgcttggaaa acacttttgc agaatgcgcc acatgatagt atctgtggct gtagcgtgga
    53461 cgaagttcac cgcgagatgg aaacgcgttt tgccaaggtc aaccaagtag gaaactttgt
    53521 taaaagtaat ttgctcaacg agtggaaggg taaaattgct acggataagg ctcaaagtga
    53581 ctatctcttt actgtcatta acacaggctt gcatgataag gtcgatactg tcagcacagt
    53641 gattgatgtg gcgacttgtg atttcaagga attgcaccca acagaaggct acaaaaagat
    53701 ggctgctctt atcttgccaa gttaccgtgt ggaggacttg gatggtcgtc ctgtagaggc
    53761 tacaatcgaa gacctcggag ctaattttga atacgattta ccaaaagaca agttccgcca
    53821 agctcgtatt gctcgacaag tgcgcgtgac cattccagtt cacctagcac cgctttcttg
    53881 gacaaccttc caattgctgg aaggagaaca agaacaccgt gagggtattt accaaaacgg
    53941 agtgattgat acaccattcg taacggtgag tatggatgac aacatcacag tctatgataa
    54001 gacaactcac gaagcctatg aagactttat ccgctttgaa gaccgtgggg acatcggaaa
    54061 cgagtatatc tatttccaac caaaaggaac agagccaatc tttgcagagc ttaagggcca
    54121 cgaggtcttg gaaaacacag cttgctatgc taaaatcttg ctcaaacatg aattgaccgt
    54181 gcctgtcagc gcggatgaaa agctagaaga agagcaacaa ggtatcatcg agtttatgaa
    54241 gcgtgaggct ggacggtcag aagaattgac aaacattcct ctggaaactg agttgactgt
    54301 cttcgttgac aatccacaaa tccgcttcaa gactcgcttt actaacactg ccaaggatca
    54361 ccgtatccgt ctcttggtca agactcataa cacgcgtcca agtaatgatt ctgaaagtat
    54421 ctatgaggtg gtgacacgac caaacaaacc agctgcttca tgggaaaatc ctgaaaatcc
    54481 tcaacaccaa caagcttttg tcagtctgta tgacgatgaa aaaggggtga ctgtatccaa
    54541 taagggattg aatgaatacg aaatccttgg ggataacacc attgccgtga ccattttgcg
    54601 tgcatcaggt gagctaggtg actggggcta cttcccaacg ccagaagcac aatgcttgcg
    54661 ggagtttgaa gtcgaatttg cgattgaatg ccaccaagcc caagaacgct tctcagccta
    54721 tcgtcgtgcc aaagccttgc agacaccgtt taccagcctt cagcttgcta gacaggaagg
    54781 aagcgtggtt gcgactggta gcctcttgag ccattctgtt ctcagcatac cgcaagtttg
    54841 tccaacagcc tttaaagtgg cggaaaatga agaaggctat gtcctccgtt actataatat
    54901 gagtcaagaa aatgtgcgca tatcagaaca tcaacaaacc attcttgact tacttgagcg
    54961 accatatcca gttcattcag gactattggc tccacaagag attcgtacag aattcatcaa
    55021 aaaagaagaa atttaatttc aaaaagtaaa catcaaaaga aaggaggggc gaaaaggtaa
    55081 gaactaacta ctgattcgcc cctttttatg gtaaaaacaa tgaccattgc aacgattgat
    55141 atcggaggga ctgggattaa gtttgccagt ctgactcctg atgggaaaat actggataag
    55201 acaagtattt caacgcctga aaacttggag gatttactaa cgtggctaga tcaacgcttg
    55261 tcagaacagg attacagtgg gattgctatg agcgttccag gtgcggtcaa tcaagagaca
    55321 ggtgtgattg atggcttcag tgcggtgccc tatatccatg gcttttcttg gtatgaggcg
    55381 cttagctctt atcagctacc tgtccattta gaaaatgatg ccaactgcgt tggactcagt
    55441 gaactactag ctcatccaga gcttgaaaat gcagcctgtg tcgtgattgg gacagggatt
    55501 ggcggagcca tgattatcaa tggtagactt catcgaggtc gccacggtct gggtggagaa
    55561 tttggctaca tgacaaccct tgcccctgct gaaaaactta ataactggtc gcaactagca
    55621 tcaactggga atatggtacg atacgtgatt gaaaaatctg gtcatactga ttgggacggt
    55681 cgcaagattt accaagaggc cgcagctggt aatgctcttt gtcaagaagc cattgagcgc
    55741 atgaaccgca atctgacgca aggcttgctc aatatccagt atctcatcga tccagatgtc
    55801 atcagtctgg gtggctctat cagtcaaaat ccagatttta tccaaggtgt taagaaggct
    55861 gttgaagact ttgtcgatgc ctacgaagaa tacacggtcg caccagttat ccaggcctgc
    55921 acctatcacg cagatgccaa tctctacggt gcccttgtca actggctaca ggaggaaaag
    55981 caatggtaag atttacagga cttagtccca aacaaacgca agctattgag gttttaaaag
    56041 gtcacatttc tctaccagat gtggaagtgg ctgtcactca gtctgaccaa gcctctatct
    56101 ctatccaggg tgaggaaggt cactatcaat tgacctaccg caaacctcac caactttatc
    56161 gtgccttgtc cttgttggta acagttctag cagaagctga taaagtagag attgaggaac
    56221 aagcagctta cgaagatttg gcttacatgg ttgactgttc tcgaaatgcg gtgctgaatg
    56281 tggcttctgc caagcagatg attgaggtct tggctctcat gggctactca acctttgagc
    56341 tttacatgga agacacttac cagattgaag gacagcctta ctttggctat ttccgtggag
    56401 cttattcagc agaggagttg caggaaatag aagcctatgc tcaacagttt gacatgacct
    56461 ttgtaccatg catccagacc ttggcccact tgtcggcctt tgtcaaatgg ggtgtcaagg
    56521 aagtgcagga gctccgtgat gtagagaaca ttcttctcat tggcgaagaa aaggtttatg
    56581 acctgattga tggcatgttt gccacgttgt ctaaactgaa gactcgcaag gtcaatatcg
    56641 ggatggacga agcccacttg gttggtttgg gacgctacct gattttgaac ggtgttgtgg
    56701 atcgtagtct cctcatgtgc caacacttgg agcgcgtgct ggatattgct gacaaatatg
    56761 gtttccactg ccagatgtgg agtgatatgt tcttcaaact catgtcagcg gatggccagt
    56821 acgatcgtga tgtggaaatt ccagaggaaa ctcgtgtcta cctagaccgt ctcaaagacc
    56881 gtgtgactct ggtttactgg gattattatc aggatagcga ggaaaaatac aaccgtaatt
    56941 tccgcaatca tcacaagatt agccatgacc ttgcatttgc agggggagct tggaagtgga
    57001 ttggctttac acctcacaac cattttagcc gtctagtggc tatcgaggct aataaagcct
    57061 gccgtgccaa tcagattaaa gaagtcatcg taacgggttg gggagacaat ggtggtgaaa
    57121 ctgcccagtt ctctatccta ccaagcttgc aaatctgggc agaactcagc tatcgcaatg
    57181 acctagatgg tttgtctgcg cacttcaaga ccaatactgg tctaacggtt gaggatttta
    57241 tgcagattga ccttgccaac ctcttaccag acctaccagg caatctcagc ggtatcaatc
    57301 ccaaccgcta tgttttttat caggatattc tttgtccgat tcttgatcaa cacatgacac
    57361 ctgaacagga caaaccgcac ttcgctcagg ctgctgagac gcttgctaac attaaagaaa
    57421 aagctggaaa ctatgcctat ctctttgaaa ctcaggccca gttgaatgct attttaagta
    57481 gcaaagtaga tgtgggacga cgcattcgtc aggcctacca agcggatgat aaagaaagtt
    57541 tacaacaaat cgccagacaa gaattaccag aacttagaag ccaaattgaa gacttccatg
    57601 ccctctttag tcaccaatgg ctgaaagaaa acaaggtctt tggtttggat acagttgaca
    57661 tccgtatggg cggactcttg caacgcatca aacgagcaga aagccgtatc gagttttatc
    57721 tggctggtca gcttgaccgc atcgacgagc tggaagttga aatcctacca tttactgact
    57781 tctacgcaga caaggatttc gcagcaacta cagccaacca gtggcatacc attgcgacag
    57841 cgtcgacgat ttatacgact taatactctt cgaaaatctc ttcaaaccac gtcagcttcc
    57901 atctacaacc tcaaaacagt gttttgagca gcctgcagct agcttcctag tttgctcttt
    57961 gattttcatt gagtataaaa acaagaacac cttgcttggc gcagggtgtt tcgcgtgaaa
    58021 cagaagaatt atctggtttc aaatgctaca gttagacaaa cttatgataa aatagcagaa
    58081 agtgaatgtt tcctaagagc aattctatcg atgagcaatt ggaggtatta tgctacactt
    58141 aaaattagta aaacaagaaa tagaagctga aaagccagca tctgtagaag cttggatcat
    58201 ttccgtcaaa tttaaaaaag gttgctaccg acatatatag attccaaaaa caaaaacgtt
    58261 agcggaacta gcagatgtga ttttatggag ttttgatttt gcaaatgatc atgctcacac
    58321 atttttcatg gataatgttg agtggagtca tgcagattct tactttctta gctttgttag
    58381 tgacgatgtt gaagaacgtt acacagaaaa tgtctatctg gatagcctaa gtgtcaaaca
    58441 aaaatttaag tttattttcg acttcggtga tgaatggcgt tttgaatgcc aagtgctgag
    58501 agaaatcgag acagaggacg aagaagctta tctcgtacgt tcggttggaa cgtcgccaga
    58561 acaatatcca gattatgatg gttttgacta tgaagaatgg taaaattgaa atctaaaaaa
    58621 caattggaat cagtctgtgt gtaggcttag tatttcaata gacttcctgc aaaactagaa
    58681 tcctagttca tgattgataa taccagcaat caaattcatt cgtaatccga agcgtttacg
    58741 atgatttcga taggttgttg aaaatatttt aaacgttttt actttggcaa agatgttctc
    58801 aaccttgctt ctctccttag atagcgcatg gttataggct ttatcttcag ctattagcgg
    58861 cttgagtttg ctggatttac gtggagtttg tgcttgagga tatatcttca tgggcccttg
    58921 ataaccactg tcagccaaga ttttaccagc ttgtccgata tttctgcgac tcattttgaa
    58981 caacttcata tcatgacaat agttcacagt gatatccaaa gaaacaattc tcccttgact
    59041 tgtgacaatc gcttgagcct tcatagcgtg gcatttcttt ttaccagaat cattcgctag
    59101 ttcttttttt agggcgattg atttttactt ccgtcgcatc aatcattacc gtgtcctcag
    59161 aactgagagg agttcttgaa atcgtaacac cactttgaac aagagttgct tcaacccatt
    59221 ggctccgacg gattaagttg ctttcgtgaa taccaaaatc agccgcaatt tcttcataag
    59281 tgcggtattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg cttaatttag
    59341 gttttcgtcc accttttgcg tgtttaagtt gataagttgt ttttaacaca gctaacatct
    59401 cttcaaaagt ggtgcgctga acaccaacaa gacgcttaaa tcgtgcatcg gttagttgtt
    59461 tacttgcttc ataatttcgc agggagtcta ttgactcttt ggtaggtgtc aatgtttttt
    59521 tcatctatcc cgagaattat tttcccgcca tttgtatttg caaatgctga gtaggtttcc
    59581 cagaaagact ctggaagatt gtttttagct tttttgtatt ctaaatcaac cccttcaaat
    59641 tttaagtcca tatttttcct ttacatctgt tttttgtggt tctggtattt gttcaagttg
    59701 agtgataata tagcgaattg aatttcgaga gtttttactc agttaatttc ttttttaacc
    59761 cactttaatt tcttttttaa cccgggttaa aaaagaaatt aaagtgggtt aattttcctt
    59821 gactt
//
LOCUS       DAVKXA010000006        57889 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKXA010000006 DAVKXA010000000
VERSION     DAVKXA010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.006"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(99..1061)
                     /locus_tag="VW883_000400"
     CDS             complement(99..1061)
                     /locus_tag="VW883_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0273593.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            1127..2515
                     /locus_tag="VW883_000401"
     CDS             1127..2515
                     /locus_tag="VW883_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0273594.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRVGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(2550..3002)
                     /locus_tag="VW883_000402"
     CDS             complement(2550..3002)
                     /locus_tag="VW883_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0273595.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            3164..3457
                     /locus_tag="VW883_000403"
     CDS             3164..3457
                     /locus_tag="VW883_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273596.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            3613..4827
                     /locus_tag="VW883_000404"
     CDS             3613..4827
                     /locus_tag="VW883_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0273597.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            4972..5106
                     /gene="rpmH"
                     /locus_tag="VW883_000405"
     CDS             4972..5106
                     /gene="rpmH"
                     /locus_tag="VW883_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0273598.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            5390..6271
                     /locus_tag="VW883_000406"
     CDS             5390..6271
                     /locus_tag="VW883_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0273599.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLV
                     VATSGFALLGRKTRRRK"
     gene            6576..7349
                     /locus_tag="VW883_000407"
     CDS             6576..7349
                     /locus_tag="VW883_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0273600.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            7349..7909
                     /gene="rnmV"
                     /locus_tag="VW883_000408"
     CDS             7349..7909
                     /gene="rnmV"
                     /locus_tag="VW883_000408"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0273601.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            7981..8880
                     /locus_tag="VW883_000409"
     CDS             7981..8880
                     /locus_tag="VW883_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273602.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            9200..9496
                     /locus_tag="VW883_000410"
     CDS             9200..9496
                     /locus_tag="VW883_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0273603.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            9573..11603
                     /locus_tag="VW883_000411"
     CDS             9573..11603
                     /locus_tag="VW883_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0273604.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSIYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTEIGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRDLMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            11605..12246
                     /locus_tag="VW883_000412"
     CDS             11605..12246
                     /locus_tag="VW883_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273605.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            12239..12397
                     /locus_tag="VW883_000413"
     CDS             12239..12397
                     /locus_tag="VW883_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273606.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQILVHGYL
                     LDFASIEG"
     gene            12783..13655
                     /gene="rsmA"
                     /locus_tag="VW883_000414"
     CDS             12783..13655
                     /gene="rsmA"
                     /locus_tag="VW883_000414"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0273607.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            13657..14535
                     /gene="rsgA"
                     /locus_tag="VW883_000415"
     CDS             13657..14535
                     /gene="rsgA"
                     /locus_tag="VW883_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0273608.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            14546..15202
                     /locus_tag="VW883_000416"
     CDS             14546..15202
                     /locus_tag="VW883_000416"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0273609.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            15165..15827
                     /locus_tag="VW883_000417"
     CDS             15165..15827
                     /locus_tag="VW883_000417"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0273610.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            15829..17085
                     /locus_tag="VW883_000418"
     CDS             15829..17085
                     /locus_tag="VW883_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0273611.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            17075..18016
                     /locus_tag="VW883_000419"
     CDS             17075..18016
                     /locus_tag="VW883_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0273612.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEIYSQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            18283..19110
                     /gene="purR"
                     /locus_tag="VW883_000420"
     CDS             18283..19110
                     /gene="purR"
                     /locus_tag="VW883_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0273613.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            19177..20427
                     /locus_tag="VW883_000421"
     CDS             19177..20427
                     /locus_tag="VW883_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0273614.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERAAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            20553..21347
                     /gene="pflA"
                     /locus_tag="VW883_000422"
     CDS             20553..21347
                     /gene="pflA"
                     /locus_tag="VW883_000422"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0273615.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(21422..22348)
                     /gene="yidC"
                     /locus_tag="VW883_000423"
     CDS             complement(21422..22348)
                     /gene="yidC"
                     /locus_tag="VW883_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0273616.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(22426..22704)
                     /locus_tag="VW883_000424"
     CDS             complement(22426..22704)
                     /locus_tag="VW883_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0273617.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22738..23478
                     /locus_tag="VW883_000425"
     CDS             22738..23478
                     /locus_tag="VW883_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0273618.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVATGILIFHLS"
     gene            23534..24217
                     /locus_tag="VW883_000426"
     CDS             23534..24217
                     /locus_tag="VW883_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0273619.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            24330..25322
                     /locus_tag="VW883_000427"
     CDS             24330..25322
                     /locus_tag="VW883_000427"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0273620.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            25387..25926
                     /gene="rsmD"
                     /locus_tag="VW883_000428"
     CDS             25387..25926
                     /gene="rsmD"
                     /locus_tag="VW883_000428"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0273621.1"
                     /translation="MKIVSGIYGRRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            25916..26404
                     /gene="coaD"
                     /locus_tag="VW883_000429"
     CDS             25916..26404
                     /gene="coaD"
                     /locus_tag="VW883_000429"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0273622.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            26388..27425
                     /locus_tag="VW883_000430"
     CDS             26388..27425
                     /locus_tag="VW883_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0273623.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            27483..27713
                     /locus_tag="VW883_000431"
     CDS             27483..27713
                     /locus_tag="VW883_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0273624.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            27737..29020
                     /gene="murA"
                     /locus_tag="VW883_000432"
     CDS             27737..29020
                     /gene="murA"
                     /locus_tag="VW883_000432"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0273625.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEVHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            29013..29201
                     /locus_tag="VW883_000433"
     CDS             29013..29201
                     /locus_tag="VW883_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0273626.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            29240..30064
                     /gene="endA"
                     /locus_tag="VW883_000434"
     CDS             29240..30064
                     /gene="endA"
                     /locus_tag="VW883_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0273627.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            30355..31686
                     /locus_tag="VW883_000435"
     CDS             30355..31686
                     /locus_tag="VW883_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0273628.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(31884..31954)
                     /locus_tag="VW883_000436"
     tRNA            complement(31884..31954)
                     /locus_tag="VW883_000436"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31920..31922),aa:Cys,seq:gca)
     gene            32370..35981
                     /gene="rpoB"
                     /locus_tag="VW883_000437"
     CDS             32370..35981
                     /gene="rpoB"
                     /locus_tag="VW883_000437"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0273629.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            36014..39691
                     /gene="rpoC"
                     /locus_tag="VW883_000438"
     CDS             36014..39691
                     /gene="rpoC"
                     /locus_tag="VW883_000438"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0273630.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            39802..40215
                     /gene="ndk"
                     /locus_tag="VW883_000439"
     CDS             39802..40215
                     /gene="ndk"
                     /locus_tag="VW883_000439"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0273631.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(40725..41003)
                     /locus_tag="VW883_000440"
     CDS             complement(40725..41003)
                     /locus_tag="VW883_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEV0273632.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(41144..41776)
                     /locus_tag="VW883_000441"
     CDS             complement(41144..41776)
                     /locus_tag="VW883_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273633.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLNLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            complement(41778..43793)
                     /locus_tag="VW883_000442"
     CDS             complement(41778..43793)
                     /locus_tag="VW883_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0273634.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLTTSTEWHDY
                     SPNGNVLIVTPHYLERQNIPVDTTIKQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(43896..44192)
                     /locus_tag="VW883_000443"
     CDS             complement(43896..44192)
                     /locus_tag="VW883_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0273635.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            44852..45715
                     /locus_tag="VW883_000444"
     CDS             44852..45715
                     /locus_tag="VW883_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273636.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYENLEYIYRIEIERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            46098..46718
                     /locus_tag="VW883_000445"
     CDS             46098..46718
                     /locus_tag="VW883_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273637.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            46804..47247
                     /gene="tsaE"
                     /locus_tag="VW883_000446"
     CDS             46804..47247
                     /gene="tsaE"
                     /locus_tag="VW883_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0273638.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            47237..47755
                     /locus_tag="VW883_000447"
     CDS             47237..47755
                     /locus_tag="VW883_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273639.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTGE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            47763..48779
                     /locus_tag="VW883_000448"
     CDS             47763..48779
                     /locus_tag="VW883_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0273640.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            48864..50120
                     /locus_tag="VW883_000449"
     CDS             48864..50120
                     /locus_tag="VW883_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0273641.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVTNFSEVSSIFKSGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            50175..51341
                     /gene="recA"
                     /locus_tag="VW883_000450"
     CDS             50175..51341
                     /gene="recA"
                     /locus_tag="VW883_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0273642.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            51648..53018
                     /locus_tag="VW883_000451"
     CDS             51648..53018
                     /locus_tag="VW883_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0273643.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            53394..54350
                     /gene="lytA"
                     /locus_tag="VW883_000452"
     CDS             53394..54350
                     /gene="lytA"
                     /locus_tag="VW883_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0273644.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            54709..54882
                     /locus_tag="VW883_000453"
     CDS             54709..54882
                     /locus_tag="VW883_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273645.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            54869..55075
                     /locus_tag="VW883_000454"
     CDS             54869..55075
                     /locus_tag="VW883_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273646.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            55121..55480
                     /locus_tag="VW883_000455"
     CDS             55121..55480
                     /locus_tag="VW883_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273647.1"
                     /translation="MKKSSVSLILIGEGDETERKADQLASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLG"
     gene            55609..56034
                     /locus_tag="VW883_000456"
     CDS             55609..56034
                     /locus_tag="VW883_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273648.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            56442..57437
                     /locus_tag="VW883_000457"
     CDS             56442..57437
                     /locus_tag="VW883_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273649.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLLFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPFSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            57427..>57889
                     /locus_tag="VW883_000458"
     CDS             57427..>57889
                     /locus_tag="VW883_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273650.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLNEDYYNILVHEKETIQGYLVLSNCG"
BASE COUNT        17335 a        10744 c        13027 g        16783 t
ORIGIN      
        1 aaaacatgtt tttgaggttg tagatgaaac tgacgaagtc agtaaccata catacggtaa
       61 ggcgacgtga cgtggtttgc agagattttc gaagagtatt agccttccat atagtttttc
      121 aaagcctgtc ctgttagtcc ggcattgagg gcgatgagga gtttcaagcg agctttttgg
      181 gcgttgagtt ctttaacaaa gaaaacgcct gctttttgca actgtacgcc cccaccctgg
      241 taggcataaa caggctcggc aataccgtta aagcatcgtg ataccagagc gactggaatt
      301 cctttttgca gaaggctttc taatttttga gccgtttctt tgggaatatt accagctccg
      361 aaggcttgga taatcaaacc gtccaagtgt tctaaatcca gcatatcaat cagctcatct
      421 gtcataccag cataagccga gatgataggg actaaacctt gtatgtgatc aaggtcaaag
      481 cgaacacgag gttcagctgt tttgaagtag aggatttcct gtttcatgat gagaccgagg
      541 ggaccatgtg ttggagtctg gaaggtgctg acattagtcg tatgtgtttt ggtgacatac
      601 ttggcagcgt ggatttcatc gttcataacg accaaaactc ctttgtcagc agccctgtca
      661 tcgctggcca ctcgtaaagc acttaggtaa ttataaacac catcactacc gagctcattg
      721 gagctacgca tggctcctgt tagaacgata ggcatatggg gaacttccat ggtatcaagg
      781 aaataggctg tttcctctaa agtatcggtt ccgtgtgtga tcaccactcc atcgtagtta
      841 tctgcttcct ctttaatttt ctggtagagg accagcatat gtttgggttt gatatgggga
      901 cttggaagat taaaaaagtc caaggcgtgg acttggattc cttcaagtgg gttggacaca
      961 tggttcatgg gattatctga actcgtcaca acagcgccag aagcatcggc ctgcatggaa
     1021 atagttccac ccgtatgtaa aacaaggatt ttcttaggca tgatttacta actctttctg
     1081 aaatgtggta taatcattgt atcacaaaag gggagattgg aataggatgg aagtcaaagc
     1141 tgtttttttt gatatcgatg gaaccttggt caacaatcgc aagagtgttt tgaaatccac
     1201 taaggacgcg attaagattg tcaaagaaca aggggtacta gttggcgtag cgacagggcg
     1261 aggacctttt tttgttaagg aattgatgga cgatttggat ctggattttg cggtaaccta
     1321 taatggccag tatatcttta gtaaagacag agtcttgttc acgagcccta tttccaagtt
     1381 acatttgcgc catctaatta gctatgctaa aaaagagggc acggagattg ctctagggac
     1441 caaggatgcc atgttgggtt ctaaaatcat gtcctttggt ctgggttctt tttcccaacg
     1501 aattagtcgc ttcgttccct ctgttttaac tcggacggtg agtcagtctt ttaatcgcat
     1561 ggtcagcaag gttgttcccc aaaaggaaga ggacctgctt cacctgatga atcaacctat
     1621 ctaccaagtt ttgatgctga tgacaccaga agaatctgag aaggcggcag ctgattttga
     1681 agacttgaaa ttgacacgta gcaatccttt tgcatcggat gtcatcaatc agggaaattc
     1741 taaattagaa ggcattcgcc gagttgggaa agaatatggc tttgacctca accaagtcat
     1801 ggcttttggt gactcagata atgatcttga aatgctggct ggcgtcggta tgtcggtcgc
     1861 tatgggaaat ggtagtagca gtgtcaagga agctgccaag cacattacca ctagcaatca
     1921 acaagatgga atccacaagg ccttggaaca ttttggtgtt ttgtcttcag aaaaagtctt
     1981 tgtcagccgt gactatcatt tcaataaggt caagaccttc caccacatga tggatgaacg
     2041 aacccaagaa gaacctcgag cttgggattt agagggtgca acccataggg ttggttttaa
     2101 aatagaagaa ttggtggagt ttgttcgagc agccagtcct tctgaagaag attttggtca
     2161 agctgtatcg caacttcatc aggcccttga taaggcagca gataaagtag ccaagaagac
     2221 acctgctcag caagatttga tagggcaagt ggatgccttg attgacacgc tttacttcac
     2281 ctacggcagt tttgtcttga tgggggtgga cccagaacgt atttttgata ttgtccatca
     2341 ggccaatatg gggaaaattt ttccagatgg caaggctcat tttgatccag tgacccataa
     2401 aatcttaaaa ccagataatt gggaagaaaa atatgctcca gaacctgcta ttaaaaagga
     2461 actgcagcgc cagctcaagg cttacgaacg ccataaagag agaaataaat cgtaaacaaa
     2521 aaggagctag gggctccttt tctttgtgat tataaggttt tttcttgttc tctcacaacc
     2581 agcaaatcga ccttagcatg gcggagtatg tattcagatg aagagccgac caagaggcgt
     2641 tcaaaggcgt tgagaccagt tgcgccaacg aggatgaggt ccacttcctc ggcatctgga
     2701 atagtacgtg ctagcagggt ctttggattt cccatttcaa tgacgatatg aacatctgct
     2761 accccagcat ctttagcacg tttttcgtac tctttcatca gactttcagc gtcgacttgg
     2821 agttcttcgt aaacttcagc atcaaaggtg gatacgcttt ggagagcgcg tgtgtcaatg
     2881 acatgtgcga tggtgagttt agcgtcgttt cgtagagcag aatgaactcc cttgacaaaa
     2941 gccaagtccg cttccttaga accatcgatt gcgaccatga tattttggta acgttgtgcc
     3001 ataatgaaac ctcctgaaat tttcttacta taattgtaaa ccttttcact atagaagtaa
     3061 agcaaaaaaa gtatttttca aaagaatatt agggcttaaa atctatataa atatatgatg
     3121 aaataaaaga aaggatagca ggaaagaagt gaaggaaggg agaatgatga aaaactcttt
     3181 tcaaaaatca aatttccttt attatggaat tatcctagtt tcagtcttgg tagaagtgat
     3241 catgatctgg caattagaga gtctggtacc gcttctttat ccaagtttta ttggattttt
     3301 agtctttcat gtactctacc atctaatctt atttctagtt gcaaaacgaa gtgggcgttg
     3361 ggattacttg atgatatggg ggcttttcct catgtttaat cttctttatg actcctttct
     3421 aggcttgctt tttctaggtt tatcttttgg tatgtgatgt gtctttgcaa aatacctgct
     3481 atctctacgt tcttaacctc gcctttagca aggtttttct tctatacgaa actagtaaca
     3541 catttcagta aacttgtcgc attctctttc tagtggtata atgttactat cctgatgaat
     3601 tgaggaaaca agatgaaaga atataacaag tctagtaagt tagagcatgt tgcttatgat
     3661 atccgtggtc ctgtattgga agaagccatg cggatgcgag cgaatggaga aaagatttta
     3721 cgtctgaata caggaaatcc agcagaattt ggctttacag cgccagacga ggtcattcat
     3781 gacttgatta tgaatgcgcg tgatagtgaa ggctattctg actccaaagg gattttctca
     3841 gcccgtaagg ccatcatgca gtattgccag ctgaagaaat tcccaaacgt agatattgat
     3901 gatatttacc ttggaaatgg tgtcagtgag ttgattgtca tgtccatgca ggggcttttg
     3961 gacaatgggg atgaggtctt agtgccaatg ccagactatc ctctatggac ggcggctgtc
     4021 agcctagctg gaggaaatgc cgttcactat atctgtgatg aagctgtgga atggtaccca
     4081 gatattgacg atatcaagtc aaaaatcact tccaatacca aggcaattgt ccttatcaat
     4141 ccaaataacc caactggagc cctttatcct aaggaactct tgctggagat tattgagatt
     4201 gcccgtcaaa acgatttgat tatctttgcg gatgaaatct atgaccgcat ggtaatggac
     4261 ggacatgtgc atacgcctgt ggcgagcttg gcaccagatg tcttctgtgt cagcatgaat
     4321 ggtctgtcaa aatcccaccg catagcaggt ttccgtgtgg gttggatggt cttgtctggc
     4381 cctaagactc atgttaaggg ctatatcgaa gggctcaata tgctgtccaa tatgcgcctt
     4441 tgctctaacg ttttggccca acaagtcgta caaacttcct tggggggtca ccaatcagtc
     4501 gatgaattgc ttcttcctgg tggacgaatc tacgagcaaa gaaatttcat ctataatgcc
     4561 attcaagata ttccaggttt gtctgccgtt aaacccaagg cggggctcta tatcttccca
     4621 aaaatcgacc gcaatatgta ccgtatcgat gatgatgagc agtttgtcct tgatttcttg
     4681 aagcaggaaa aggttctctt ggttcatggt cgaggcttta actggcagga accagaccac
     4741 ttccgtatcg tttaccttcc tcgtgttgat gagttagccc aaatccaaga aaagatgact
     4801 cgtttcttga aacagtatcg tagatagggc ttgcattcga aaaagctgga aacatttgcc
     4861 tagagctatt gacaaaagtg aaagaatcag atagaatagt aaagtatgtt tagtaactga
     4921 tcactttata gccggctaaa cgaatacaaa atctatgagg aggtattcat cgtgaaacgt
     4981 acttatcaac caagtaaact tcgtcgtgcg cgcaaacacg gattccgtaa ccgtatgtca
     5041 actaaaaatg gtcgtcgcgt attggcagct cgtcgtcgta aaggacgcaa agttttggct
     5101 gcataatcca aacgaattct atcaaaaatc agtaggaact cgagtctact gatttttatt
     5161 tttgtaaaaa agttcagtag atgcaaatgg attcggaagc gatgttatag tagattgaaa
     5221 ctagaatagt acacctctat ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
     5281 gatttgtcct gttattattt cattttacta taaagttgaa gtagctggag atggcacagc
     5341 gacaatcgtc tttaaagatg gttcagctat tacaattcca ggaaatcaat tggtagcaca
     5401 agatccaaaa gcacaagata gcactaaacc gactgctgaa aaatcaactg ttaaagcacc
     5461 tgctcaaaga gtagatgtaa aagatataac tcatttaaca gatgaagaaa aagttaaggt
     5521 tgctatttta caagcaaatg gttcagcatt agacggagcg acaatcaatg tagctggaga
     5581 tggtacagca acaatcacat tcccagatgg ttcagtagtg acgattctag gaaaagatac
     5641 agttcaacaa tctgcgaaag gtgaatctgt aactcaagaa gctacaccag agtataagct
     5701 agaaaataca ccaggtggag ataagggagg caatactgga agctcagatg ctaatgcgaa
     5761 tgcaggcggt ggtagccagg cgggtggatc agctcacaca ggttcacaaa actcagctca
     5821 atcacaagct tctaagcaat tagctactga aaaagaatca gctaaaaatg ccattgaaaa
     5881 agcagccaag gacaagcagg atgaaatcaa aggcgcaccg ctttctgata aagaaaaagc
     5941 agaactttta gcaagagtgg aagcagaaaa acaagcagct ctcaaagaga ttgaaaatgc
     6001 gaaaactatg gaagatgtga aggaagcaga aacgattgga gtgcaagcca ttgtcatggt
     6061 tacagttcct aagagaccag tggctcctaa gacaacaagt gcaccgcaag caactgcagg
     6121 aacaatgcaa gatgttacct accagtcacc tgctggcaaa caattaccta acacaggttc
     6181 agcatcaagt gcagcacttg ctagtcttgg tctagtggtg gcaacaagtg gttttgcttt
     6241 gctaggaaga aagactagac gtagaaaata gaacagctag aaaattctat tctctactta
     6301 aagttagatt ataaggggga ttttgagaag tcatcaatcc tagtgatggg tgagaaaagt
     6361 gagaacccaa gataatcaca tactttagct gaataggaat attctatcaa tgtagccaat
     6421 ctcttctgtc tctaactgtg gaataggaga tgggcaatat cggatagaaa agatagcaga
     6481 atagctctct attgaagaga ggaggggaaa ccgaaaaatt aggtgcccct cctctttttt
     6541 ggtataatag aagatagaaa acgaggttag aagagatgat ttttgataca catacacact
     6601 tgaatgtaga agaatttgca ggtcgtgagg cagaagaaat tgccttggct gctgagatgg
     6661 gtgtgacaca gatgaatatt gttggttttg ataaaccgac gattgagcgt gccttggagt
     6721 tggtagatga gtatgatcag ctctatgcga ctattggttg gcatcctaca gaagctggta
     6781 cttatacaga ggaagttgag gcttacttgt tggataagtt aaaacatccc aaggttgtgg
     6841 ctttaggtga aattggctta gattaccatt ggatgacagc gcccaaagag gtgcaggagc
     6901 aggtttttcg ccgtcagatt cagctatcta aggacttgga tttgcctttt gttgtccata
     6961 cccgtgatgc gctggaagat acctatgaga ttatcaagag tgagggcgtt ggtcctcgtg
     7021 gtggtatcat gcattcattt tcagggacgc ttgagtgggc agagaagttt gtggatcttg
     7081 gtatgaccat ttccttctca ggagtggtga cttttaagaa ggcaactgac ctccaagaag
     7141 cagctaaaga gttacctttg gacaagattt tggtggaaac agatgcgcct tacttagcac
     7201 ctgtacccaa gcgtggtcgt gaaaataaaa cagcctatac tcgctatgtg gtcgacttta
     7261 tcgctgactt gcgtggtatg acgacagaag agctggcggt agcaacgact gcaaatgcag
     7321 aacgaatttt tggattggac agcaagtaat gaaagagaaa atttctcaag ttatcgtggt
     7381 tgaagggcgt gatgatacgg tcaatctcaa acgttatttc gatgtggaga cctatgagac
     7441 tcgaggttct gccatcaatg ctcaggatat agagcggatt cagcgcctgc accaacgtca
     7501 tggagtcatt gtctttacag acccagattt taatggggag cggattcggc gcatgattat
     7561 gacggccatt ccaacagttc ggcatgcctt tctcaagcga gatgaagctg ttccaaagtc
     7621 caagaccaag gggcgttctc tgggaattga gcatgccagc tatgaagacc tgaaaacggc
     7681 tctagctcag gtgacagaac aatttgaaca tgagagtcag tttgacatta gtcgtagcga
     7741 tttgattcgc cttggttttc tagcaggggc agacagccgt aagcgtagag aatatctcgg
     7801 agagactctc cgaatcggct attccaacgg caagcaactc ctcaaacgcc tagagttgtt
     7861 tggggttact ttggcagaag tggaagaagc tatgaaatct tatgagtagg aaagatgtag
     7921 ccgttacaat tttttaagtt tcacagtatt tttcgaagca ggtagaagag gaggcgtctg
     7981 atgttaattg gtcaaaaaat taaagagatt cggatagaaa aaggaattag tcgtccagat
     8041 ttttgtggag atgagcaaga actgacagtt cgtcaactgt cgcgaattga aagtggagct
     8101 tcgcaaccga gtttgcccaa gttagactat attgctcgcc ggctaggagt tccagtttat
     8161 agccttatgc cggatttttc agctcttcct tctgcttatt tagaattgaa ataccagatt
     8221 ttacgtgaac caatctatgg taaagaagag gagtacgata agaaggaagc gtgtttggaa
     8281 gagatttata aaacatactt tgataatctt cctaaagaag aacaattagc atgtgaagta
     8341 ttgcaggcgt gtttggatac ttctagaact agaaggcctg aatatgcaga gttaatactt
     8401 gaggaacata tgcctcagat tatagaaaaa gaagcttatt caataaatga tatgttgttg
     8461 attcgtttgt ttttttatca aatgctcatt agaaaagatc ttgccaaatt tataaatcaa
     8521 atcgaaaagc taatgctctt tcttttggaa cagaagaagg taactcaaat agagaattac
     8581 tttataatta gagatactct tatttcagga atgtgttgtc ttgaaaaggt aggagtaact
     8641 gattgtttta atgattatct atcgtgttta caagaaatta tggataaaac tcaagattat
     8701 caaaagaaac ctcttgtatt tatgtttttg tggaagcaag cattaagagt agaaagagat
     8761 tttagtttag cggaatcatt ttatcagtct tctaaaacat ttgcgaagct aattggagat
     8821 ggatttctag taaagaaatt gacagaggaa tggcaagagg atgtcaaaaa atatttataa
     8881 acatagtgaa tcagtgacaa aaatgtcctt gtcctcgtat caaaacagtt ctaaagttcg
     8941 tctttagaac tgttttttta gatataagct aaaaataata tgaaatagtt agattttaag
     9001 gacattgatg tccttgatag tgtgataaag atggagtata atgactataa aagttcattt
     9061 cagggtgcta ttttgacaat ttagagaaaa acaaataatt ttagaatatc atttggtaat
     9121 ataatagtat caacgttgat aatggaaaga ggagcaagta actcaacaat cttgtaatca
     9181 aaaatagagg agtatcaata tgaaacaaac agttaaaaag ttagctcttg tagcgagcat
     9241 tgcagcaaca ttaggtggag gtgtatcagt tgcctctgca gccgttcaat acccagaagg
     9301 tggtgtttgg acttatggtt caggtaacgg tggtgcttac tcaaactact atcacccttc
     9361 aaaataccat agttcaacag ttgttagcag aaaaactggt tcatctgaca agggatatgc
     9421 tggtgctgga gggacttctc gtgcatggat tcgtacttct tggggagaga aagttgcatt
     9481 ctactataat gtttagaatg gtatagccct attgtttagc tttacttggt caccttctca
     9541 ctaagtgacc aagtaacttt ttggaggaaa tgatgaaacg tttatttatt ttgatttcaa
     9601 tggtattggt atcgctttat atggtgataa cttccgttga ccatcgagaa gagattttat
     9661 ttggtaacta tccttctgtt gatgtgacag gaatgatgat aaatcaacca gtagctagtc
     9721 gcgaagaggt gacagaggct ttgagtcact tggcggtaga gcacaatagt ctcattgctc
     9781 gtcgaatcgt tgagccaaat gaagctggag aaacacgctt tacctatgcc acttatggtg
     9841 agggaaagct tccagaaggt ctgaccattt cctccaagga gagtgcagaa acgagtgatt
     9901 tattagggtc ttacttgatt gtatcaggaa gtttggatgg agtgagctta cagaccacct
     9961 tgaaagagct tggttatcaa ggctttgttt cgaatggaga agatccattt tcgatagtct
    10021 tactattgac ggccacccct atggtgctac tgagtttagc tatttttctg ctgaccttta
    10081 tgagtctgac cctgatttat cggatcaaat cccttcgtca ggcagggatt cgcttaatag
    10141 ctggtgagag cttgtttgga gttgctctca gaccagtgtt agaagatgtg agacagctta
    10201 tctgctcagt gctggtatcc agtcttttgg gattggggat tctctggtat caaggtgcct
    10261 tgtttatggc aacggtgcaa ctggtcatca ttgctcttct actttatgga ttgaccttgg
    10321 cagggatttc taccttacta agtgtcgtct atctacttgg tttacaggaa aatagtctgg
    10381 tggatctatt gaaagggaaa ctccctctca aacgtatgat gacattgatg atggtggggc
    10441 aactcttagc tgtattggtg gtcggatcga gtgcgacagc tctcctaccc cactaccgtg
    10501 aaatgcagga aatggagaga gctagcaata aatggagcca gtcctcagac cgttaccgtc
    10561 tatcctttgg ttggtctagt gcatttgccg atgaagaagg aacgcgtaag gataatcgtg
    10621 agtggcagac atttactgaa gaacggttag ccaatacaga ctctttttat attatgagca
    10681 atgttgacaa tttctcagat ggagcagaag tggacctaga tggcaatcgt ctcagtgact
    10741 acacaccgtc agggaatgtt atctatgtct caccgcgcta tctgatagaa gaaaagatta
    10801 ccgtttcttc agagtttatg gacaagatgc aaaacttgtc tgagggagag tttgggctga
    10861 tcttgcctga gagcttgcga gagcagtcta tctactacca aggattgttt acagattacc
    10921 tgcaaaactt ttcatctgaa agtgtagaag tgacgagtca gaaacactac ctcccacagg
    10981 taaggctagc ttttacagaa ataggacagg aacgtttcct ctataatgat gggtacaaga
    11041 caacacgcca gtacctaaaa gatccgatta ttgtagttct aacgccgcaa gcgactggaa
    11101 caagacctgt tgcagggatg ttgtggggaa ctacggctaa tagtgccttg aaactagatc
    11161 gatatggaga cagcatcaca gctctaaaag agcaaggtct gtatcacaag gtttcttact
    11221 tggtaaaaag ccagctattt tttgccaagg tactaaatga caaacgggtg gagttttact
    11281 ctctccttat tgggacgatt ttgaccctgt ctacggctat cttgttattt gattccatga
    11341 atcttctcta ttttgagcag ttcagacggg atcttatgat taaacgtctt gctggtatga
    11401 caatctatga gcttcatggc aagtatttac tggcgcaagg aggagttctc ttgcttggcc
    11461 tagtcctatc tagtattttg acaagagatg gtttgattag cgctctagtt gtagctttgt
    11521 ttacgcttaa cgccctcttg attttagtaa ggcaggacaa aaaagaagaa gctggtagca
    11581 tggcagtatt gaaaggaaaa taagatgatt gatattcaag gattggaaaa gaaatttaat
    11641 gaccgcgcga ttttctctgg tttgaatctc aagctggaga agggcaaggt ttatgcctta
    11701 atcggaaaga gtggaagcgg aaagacgacg ctgctgaata tcttgggaaa gctagaaaag
    11761 atagatggag gaagggttct ctatcagggg aaagatttaa aaaccattcc cactcgtgag
    11821 tattttcgag atcagatggg ctatctcttt caaaattttg gcctcttaga aaaccaatca
    11881 atcaaagaaa atttggattt gggttttgtt ggtcagaaaa tctcaaaagt agaacgtttg
    11941 gaaaggcaag tgggggcttt agaaaaagtt aatctagggt atttggattt agaacaaaaa
    12001 atctatactt tatctggggg agaggcccaa cgagttgccc ttgctaagac tattttgaaa
    12061 aatccaccct tgattttggc agatgaacca acagcagctc ttgatcctga aaattcagag
    12121 gaggttatga atctcttggt ggatttgaaa gatgaaaatc gaattatcat cattgcgacc
    12181 cataatcccc tagtctggaa taaggctgat gaaatcattg atatgaggaa acttgctcat
    12241 gtgtgaaaaa atccgtattc gcagggtatc tgattatcct agtgccagag gtggtttaga
    12301 agatatcctc atcatggaaa atatgaccaa tcatctcctt ttggttcaaa tcctagtgca
    12361 tggctatttg cttgattttg ctagtattga agggtaaagg caaaagcatt atcgtttgaa
    12421 aaatttacct caaacggttg aactgacagt ggatgatgtg gaggaggatg tggatttgac
    12481 cctacccgaa aatagaagtt atcaagaagc tgattttttt gatactcaat gaaaatcaaa
    12541 gagcaaacta ggaagctagc cgcaggctgt acttgagtac ggcaaggtga agctgacgtg
    12601 gtttgaagag attttcgaag agtatgaacg tatgtttcga gagaagcgct aagtccctct
    12661 ttaaagattt ccaagactat ctttcttcat gaggaaagat agttttttgg tatgattttc
    12721 attcccaaaa tacaagggga atgtgttaca atagtagtaa cagataatag aaaagagaat
    12781 agatgagaat tgcagattat agcgtgacca aggcagtgct ggagcgtcac ggttttacct
    12841 ttaaaaagtc cttcgggcaa aatttcctga cggataccaa tatccttcaa aaaattgtgg
    12901 atacggctga aattgatgac caggtcaatg tcatcgaaat cgggccaggt attggtgcct
    12961 tgacagaatt tttggctgag cgtgcagccc aagtcatggc ttttgagatt gaccaccgtt
    13021 tggtgccaat tttggcagat actctgcgtg attttgataa tgtgaccgta gttaacgaag
    13081 atattctcaa ggttgatttg gcgcaacata tccagaattt taaaaatcct gacctgccaa
    13141 tcaaggtagt ggctaatttg ccttactaca tcacgacgcc tattctcatg cacttgattg
    13201 agagtggcat tcctttttgt gagtttgtgg tcatgatgca gaaagaagta gcggaccgca
    13261 tttcagccca gcctaacacc aaggcttacg gtagcttgtc tatcgccgtg cagtattaca
    13321 tgacagccaa ggttgccttt atcgtgcctc gtacggtctt tgtgccagcg ccaaatgtgg
    13381 attcagccat cttgaaaatg gtgcgtcgtc cagagccagc cgtagcagta gaagatgaga
    13441 actttttctt taaggtttcc aaggctagtt ttacccatcg ccgcaagacc ttgtggaata
    13501 acttgacagg ttactttggt aagactgaag aggtcaagga caagctgacc aaggctttgg
    13561 accaggcagg cttgtcacca agtgtgcgtg gggaagctct cagcttggca gaatttgccg
    13621 gtctagcaga cgcacttaaa gggcaaggac tctaagatgc agggacaaat cattaaagcc
    13681 ttggcaggtt tctactatgt ggagagtgat ggccaggttt atcaaacacg cgcgcgtggg
    13741 aatttccgta aaaaaggcca taccccttat gttggggact gggtggattt ctctgccgag
    13801 gaaaattcag aaggctatat cctcaaaatt cacgaacgga aaaacagtct ggttcgtccg
    13861 cctattgtca atatcgatca agctgtagta atcatgtccg tcaaggaacc tgattttaac
    13921 agcaatttgc tggatcgttt cttggttctt ttggagcaca agggcatcca tcccattgtc
    13981 tatatttcca aaatggattt gttggaagat aggggagaac tggattttta ccagcagacc
    14041 tatggtgaca tcggctatga ctttgtgacc agtaaagagg aactcctgtc tttgttaaca
    14101 ggcaaggtta cggtctttat ggggcagaca ggtgttggga agtcaactct tctcaataaa
    14161 ctcgtaccag acctcaatct tgaaacggga gaaatttcag acagtctagg tcgcggtcgc
    14221 cataccactc gagctgttag tttttacaat ctcaacgggg gtaaaatcgc agatacacca
    14281 ggcttttcat ctctggacta tgaagtatca agggctgaag acctcaatca ggctttccca
    14341 gagattgcta ctgttagccg agattgtaag ttccgtactt gtacccatac ccatgagccg
    14401 tcttgtgccg tcaaaccagc tgttgaagag ggtgttattg caaccttccg ttttgacaat
    14461 tacctgcaat tccttagtga aattgaaaat cgtagagaaa cctataaaaa agtcagcaaa
    14521 aaaattccaa aataaggaga aacctatgtc tcaatacaag attgctccgt caattctggc
    14581 agcagattat gccaactttg aacgtgaaat caaacgtcta gaagcaactg gggcagaata
    14641 tgcccatatc gatatcatgg acagtcattt tgtaccgcaa atcagttttg gtgcaggtgt
    14701 ggtcgagagc cttcgtcctc atagtaagat ggttttcgat tgccacttga tggtgtcaaa
    14761 ccctgagcat catctggaag attttgcgcg tgcaggtgca gacatcatca gtatccatgt
    14821 agaagcaacg cctcatattc atggcgccct ccaaaaaatt cgttcactcg gagttaagcc
    14881 ttcagtcgtt atcaatcctg gcacaccagt tgaagccatc aagcacgtcc ttcatctagt
    14941 tgaccaagtt ttagtcatga cggttaatcc aggttttggt gggcaagcct ttctgccaga
    15001 aaccatggat aaggttcgtg agttggttgc tcttcgtgag gaaaaaggtt tgaactttga
    15061 aatcgaagtg gatggtggga ttgatgacca aactattgct caagccaaag aagctggtgc
    15121 gactgttttt gtagcaggtt cctatgtctt taagggagaa gtcaatgagc gagtacaaac
    15181 tctcagaaaa caactggact agggttgcag tttttgcagg cggaaaccgc ggtcattatc
    15241 ggacagattt tgatgctttt gttggggtgg atcgaggctc gctctgggtc ttggaagaag
    15301 acttacctct tgctctagca gtcggagatt ttgattctgt gacggaagaa gagcgacagg
    15361 tgattcaaaa acgtgcccag cattttgtcc aagcccggcc agaaaaagat gatactgatt
    15421 tggaattggc tctcttgacc atctttaagc aaaatcctca ggctcaggtt actattttcg
    15481 gtgccttggg tggccgtatt gaccatatgt tggccaatgt ctttctgcct agcaatccta
    15541 agttggcacc ctatatgcat caaatagaaa ttgaggatgg gcaaaacttg attacttatt
    15601 gtccagaagg aatcagtcag ctagaacctc gttcagacta cgactatcta gcctttatgc
    15661 cagttcggga tagccagctg actattcttg gagccaagta tgagttgaca gaggaaaatt
    15721 ttttctttaa aaaagtgtac gcttctaacg aatatataga tagggaagtg tcggtaactt
    15781 gcccagatgg ttatgtggtc gtactgcata gcaaggacag gaggtaggat ggaaagttta
    15841 cttattctat tattaattgc caacctagct ggtctttttc tgatttggca aaggcaggat
    15901 aggcaggaga aacacttaag taagagcttg gaggatcagg cagatcattt gtcagaccag
    15961 ttggattacc gctttgacca agccagacaa gccagccagt tagaccaaaa agatttggaa
    16021 gtggctgtca gcgaccgttt gcaagaagtg cggattgaat tgcaccaagg cctgacccaa
    16081 gtccgtcaag aaatgacaga taatctcctc caaactagag acaagacaga ccaacgtctc
    16141 caagccttgc aggaatcaaa tgagcaacgt ttggaacaaa tgcgccagac ggtcgaggaa
    16201 aaactagaaa agaccttgca gacacgctta caggcttcct ttgagacagt ttctaaacaa
    16261 ctggagtctg tcaatcgtgg tcttggagaa atgcagacag ttgcccgtga tgtcggagct
    16321 cttaacaagg ttctctctgg aaccaagacg cgagggattc tgggagaatt gcaactgggg
    16381 caaattattg aagacatcat gacacctgcc cagtacgaac gagaatacgc aacggttgaa
    16441 aactctagtg aacgagtgga gtatgccatc aagttacccg gacaaggcga ccaagaatac
    16501 gtctacctac caattgactc taagtttcca ctggcagatt attaccgctt agaagaagcc
    16561 tatgaagtag gtgacaagga tgaaatcgaa cgctgtcgta agtcactcct agcaagtgtc
    16621 aagcgttttg ctagggatat taggaacaag tacatagcac cacctcggac gaccaatttt
    16681 ggagttttgt ttgttccgac agaaggtctc tactcagaaa tcgtccgcaa tccggtcttc
    16741 tttgatgatt tgagacggga agaacagatt atcgttgcag gaccaagtac cctatcagcc
    16801 cttcttaact ccctatcagt tggtttcaag acccttaata tccaaaagag tgccgaccat
    16861 atcagcaaga ctcttgccag tgtcaagacc gagtttggca agtttggtgg tattctggtc
    16921 aaggcacaaa aacatctcca acatgcctct ggcaatattg atgaattatt aaaccgtcgt
    16981 accatagcta tcgagcggac gctccgtcac attgagttgt cagaaggcga gcctgcgctt
    17041 gatctactcc attttcaaga aaatgaggaa gaatatgaag attagtcaca tgaaaaaaga
    17101 tgagctattt gaaggctttt acctaatcaa atcagctgac ctgaggcaaa ctcgagctgg
    17161 gaaaaactac ctagccttta ccttccaaga tgatagtggc gagattgatg ggaagctctg
    17221 ggatgcccaa cctcataaca ttgaggcctt taccgcaggt aaggttgtcc acatgaaagg
    17281 acgccgagaa gtttataaca atacccctca agtcaatcaa attactctcc gcctgcctca
    17341 agctggtgaa cccaatgacc cagccgattt caaggtcaag tcaccagttg atgtcaagga
    17401 aattcgtgac tacatgtcgc aaatgatttt caaaattgaa aatcctgtct ggcaacggat
    17461 tgtccgaaat ctctacacca agtatgataa ggaattctac tcctatccag ctgccaagac
    17521 caaccaccat gcctttgaaa cgggcttggc ttatcatacg gcgaccatgg tacgtttggc
    17581 agacgctatt agcgagatct attctcagct caataagagt ctgctctatg cggggattat
    17641 gttgcacgac ttggctaagg tcatcgagtt gacgggacca gaccagaccg agtacacggt
    17701 cagaggcaat cttcttggac atatcgctct gattgatagc gaaattacca agacagttat
    17761 ggaactcggc atcgatgata ccaaggaaga agtcgttttg cttcgtcatg tcatcctcag
    17821 tcaccacggc ttgcttgaat atggaagtcc agtccgtcca cgtattatgg aggcagagat
    17881 tatccatatg attgacaatc tggatgcaag catgatgatg atgtcaacag ctctggcttt
    17941 ggtggataaa ggagagatgt ccaataaaat cttcgctatg gataatcgtt ccttctataa
    18001 accagattta gattgataat ttaagaaaaa tgagcatttt ttaggataag aatgttcgtt
    18061 tttttatgtg aatatggtat aataagtaaa agacaaaaat gaatactctt cgaaaatctc
    18121 ttcaaactag ggtagtatcg ctttgtcgta tgtatatatg caggtatatt acagggtttg
    18181 tcagttctat cgacaatctc aaaacagtgt tttgaaccac cagcgaccag ctttctagtt
    18241 tgctttttga ttttttgaat aaaaatggaa taggaaatag aaatgaaatt aagaagaagt
    18301 gatcggatgg ttgtcatttc caactatttg attaataatc cttataaact aactagtctc
    18361 aatacttttg ctgaaaagta tgagtctgct aaatcatcca tctcagaaga tatcgtcatt
    18421 atcaaacgcg cctttgagga aattgaaatc ggtcatatcc agacagtgac tggggctggc
    18481 ggaggtgtca tcttcacacc gtctatttcg agtcaggatg ctaaggaaat ggttgaagac
    18541 ttgcgtacca agttgtcaga aagtgaccgt atcttgccag gtggttatat ctatctgtct
    18601 gatttgctta gcacaccagc catcttgaaa aatattggtc gtattattgc caaaagcttt
    18661 atggaccaaa aaattgacgc ggttatgacc gtagcaacta agggtgtgcc acttgcaaat
    18721 gcagttgcca atgtcctcaa tgtctctttt gtcattgtgc gccgtgacct gaaaattacc
    18781 gaaggttcaa ctgttagcgt caactatgtt tcaggttcaa gtggtgaccg tatcgagaaa
    18841 atgttccttt caaaacgtag tcttaaggca ggcagccgtg tcttgattgt ggatgacttc
    18901 ttgaaaggtg gcggaacggt caacggtatg attagtctct tgcgcgagtt cgactcagaa
    18961 ctggcaggtg tagcggtctt tgcggacaat gcccaagaag aacgtgaaaa gcagtttgac
    19021 tacaagtcac tcttgaaggt aactaatatt gatgtcaaga accaagccat cgatgttgag
    19081 gttggcaata tctttgacga agataaataa gagatagaac taaaggttgg aacgattgtc
    19141 ccagcctttc tttgcaaaca gaatagaagg aagcttatga aaacaccatt tatcaataga
    19201 gaagagttag aagcgattgt tgccgagttc ccgactccct ttcacttgta tgatgagaag
    19261 gggattcgtg agaaggcaag agccgtcaac caagcttttt cgtggaacaa gggctttaag
    19321 gaatattttg cagttaaggc tactccaact ccagctattt tgaaaattct ccaagaagaa
    19381 ggttgtggtg tggactgctc tagttatgta gagcttttga tgagccataa actggacttt
    19441 ctgggttctg agattatgtt ctcttccaac aacacgccag acaaggaata cgcctatgca
    19501 cgtgaattgg gtgcgaccat taacttggat gcctttgaag atattgaaca tctggagaga
    19561 gcagcaggta ttccagaaat catctcttgt cgttataatc ctggaggcgt ttttgaactg
    19621 gggacagaca ttatggacaa tcctggggag gctaagtttg gcatgaccaa ggaccagctc
    19681 tttgaagcct ttgctatctt gaaggaaaaa ggagccaaga cttttgggat tcactccttc
    19741 ctagcgtcca ataccgtgac ccatctctat tatccagagt tggctcgtca gctctttgaa
    19801 ctggctgttg aaatcaagga aaagttgggc atttggctag actttatcaa tctttctggc
    19861 ggtattggtg ttaattatcg tccagaccag gagccgaacg atatcgcctt gattggtgag
    19921 ggagttcgta aggtgtatga agaagttctt acgtcagcag gtcttggtca ggtcaagatt
    19981 ttcaccgaat tgggtcgttt tatgctggca cctcacggtg ctctagtcac aagagtgact
    20041 cataagaagg aaacctaccg tacctatcta ggtgtggatg cctcagcagt caacctcatg
    20101 cgtccagcta tgtacggagc ttaccatcat attagcaacg tgacccatcc agatggacca
    20161 gctgaagcgg tagatgtggt tggttcactc tgtgaaaaca atgataaatt tgcagtcaat
    20221 cgcgaactgc ctcatacaga aatcggtgat ttgctggtca ttcatgatac aggtgcccac
    20281 ggattttcaa tgggctacca gtataatgcc aaattacgtt ctgcggaaat cctctatacc
    20341 gaagaaggta aagcccgtca aatccgccgt gcagagcgcc ctgaggacta ttttgcaacc
    20401 ttatatggct tcgattttga agaataatct gataatagat tgaaaatgaa attgaaaaac
    20461 agattgcttt ctaaaaaata ggcaaaaatc ttgtttttcc ttcaagtcgt gatataataa
    20521 aactataaaa cgttttcaag gaaggtaacg atatgtctga agaaacaatt gattatggac
    20581 aagtgacagg aatggtgcat tcgacagaaa gctttgggtc agtagatggg cctggtattc
    20641 gctttattgt ctttttgcag ggctgtcaca tgcgttgcca gtattgccac aacccagaca
    20701 cttgggctat ggagtccaat aagtcacgtg aacggacggt agatgatgtc ttgacagagg
    20761 ccttgcgcta ccgtggtttc tggggaaata agggtgggat tacagtcagt ggaggagaag
    20821 ctctcttgca gattgatttc ctgattgctc tcttcaccaa ggctaaggaa caaggaatcc
    20881 actgtacctt ggatacctgt gctcttcctt tccgtaataa accacgttac cttgagaagt
    20941 ttgacaaact catggctgtc actgacttgg ttcttttgga tatcaaggaa atcaacgaag
    21001 aacagcacaa gattgtcact agacaaacta ataaaaatat cttggcttgt gcccagtatc
    21061 tatcagatat tggaaaacct gtctggattc gccacgtgct agttccagga ttgacagaca
    21121 gagatgatga cttgattgaa cttggtaagt tcgtcaagac cctcaaaaat gttgataagt
    21181 ttgaaattct accttatcac accatgggtg agttcaagtg gcgtgaactt ggaattccat
    21241 attccctcga aggagtcaaa ccaccaacag cagatcgcgt caagaacgct aaaaaactca
    21301 tggataccga aagttatcaa gattatatga aacgtgtaca tggatagaaa agaagcctga
    21361 tggaaacatc gggcttttga tttgcaaaaa gacttagcaa atcagctaag cctttttctt
    21421 cttatctcga acgttgtttt ccagcgttgc gatttttgtg ttttttcttg cttgtgatag
    21481 cagttggttg ttcaggggta acgtcttttc gtccacttgg tttagagaaa gcacttgctt
    21541 ttggtgggtt cttggctagt tcttcacgga cttttttgcg aagttttgga cgaacgatat
    21601 agttgacgat aaactgttgg agaatcatca tgaaaccacc gacaacccag taaagtgtga
    21661 cactagctgg tgagaagagg gagaagacga cgatcatgag tgggctcatg taaatcattt
    21721 tcttgatttg ttctctttgc atttcatctt ctactccgtg aagtgaaagg agcgattgaa
    21781 gatagtaaag gacaccagca caggcaacca aaatcatact tggagaacct agaggaatgc
    21841 ctaggtagct tgcttgagca accccttcag tatgttgggc agcaaagtag atagcagaga
    21901 agaaaggcat ttgaaggagg atagggaaac atcctacacc accaaacatg ctgatgccgt
    21961 gctctttttg agcggcaaag agggcttgtt gggcttcgag tttttcttct tgagtagttg
    22021 cttctttgag acgtgtttgg tgtggctcaa ggacatgctt gagagcgttc atcttttcag
    22081 agtgaagcgt tgccttccat gattggtaga taccaagtgg taagataatc aagcgtacga
    22141 taatggttac gataatgata gcgacaccaa agcctagacc tttatcagta gcgaagtact
    22201 tgatggcttc agccataggc gctccgatcg tattccaaat aaatcctgtt ggctgacctg
    22261 tggttttatc gacattgaca cagccagtca agacaagcaa catagccact cccatagccg
    22321 agaatgcaaa acgtttaata gatttcactg tttttattcc ttctttaaaa attatacctt
    22381 tctattctac tgttttttta caaaatatac aatagttctg gagacctaat ttgcgatttt
    22441 aaagtcagag tagggaggaa agttgcttag tttgacatct aagtagctta cttttgaaaa
    22501 aggtgtcggt ccttttcgga tttcttggat aaattttgcc atgatagcag atgagtctgc
    22561 ttgggctaag atttccactg tgccatcgtc gttattccat actcgacctg tgatgccacc
    22621 aatttcaagt gccaagctgt aaacacccca acgaaagccg actccctgta ccctaccttg
    22681 ggcaatcatt ctaacctttt gcataccaac cccctttgat tgtgttataa tatttctatg
    22741 actattataa cctcaaaagc caattctgtg gtaaaaaatg ccaagaaatt acgccaaaaa
    22801 aaataccgca agtctgccta tttgattgaa ggctggcact tgtttgaaga agctgtccaa
    22861 gctggagtga cgattgagaa aatctttgcc ctagaaaatt atcgagatca gttagctact
    22921 ttttcgcaaa ctgtctgggt gtcagaggat attttgctag atttggcgga ttctcagact
    22981 ccacagggaa ttgtggcggt ggttcaaaaa gaagaagtag gacaagctga tttgagtcag
    23041 ggcaagttct tgtttttgga agatgtgcaa gatcccggta atgtaggaac tatcattcga
    23101 actgcggatg cagcaggttt tacaggagtg attgtttcag ataagtcggc agacatctac
    23161 agtctcaaaa ccctacgttc catgcaaggt agtcatttcc atctgcccat ttaccggatg
    23221 actagtcaag cgcttcttga cgaaactaaa aaggtagcta tcccagtgct agcaacaacc
    23281 ctatctaaag attctgttga ttacagagaa ctgccttcta tagaaaattt tgtactagtt
    23341 atgggaaatg agggtcaagg aattagtccc cttatggctg aaagtgcaga ccagttggtc
    23401 catattagca tgaaggggca ggccgagagt ttgaatgttg cagttgcaac cggtatttta
    23461 atcttccatt taagctaatt ttaacttttt ttgttataat caaggaaaga tgttcacaga
    23521 aaaggagaaa aggatgaatc acactattat acatgaccgt gcaggtctca atcaatttta
    23581 cgctaaggtt tatgcctttg ttggtctggg aatcggacta tctgctttgg tatcaggcct
    23641 tatgttgacg gtctttcagt ctcagttggt ttacttgttg atgcaggggc gtctctggtt
    23701 gaccattgct acttttgcgg agttggcttt ggttttcgtt gccagtagca tggcttcaag
    23761 aaatagtcca gctgctcttc cagtattttt actttactcc gttttaaacg gctttaccct
    23821 tagttttgtg gtggctttct atactccggg tacagtttta tctgcctttg tatcgagcgc
    23881 ccttctcttc tttgtcatgg cggcagttgg tatctttacc aagaaagact tgagtgggat
    23941 tggtcgagca atgatggcag ctctcattgg tttactgatt gctatggtag tcaatatttt
    24001 cttggctagt ggcttctttg attatatgat tagcgtagcc atggttttgg ttttttcagg
    24061 gttgattgct tgggataacc aaaagattcg cctcgcctat gaacaatcac aaggtcgtgt
    24121 agcgacaggc tgggtggtgt caatggctct cagcatctat cttgatttta tcaatctttt
    24181 cctaagtatt ctacgtatct ttggtcgcaa tgactaaaag gtctatgaaa tcagtgtttt
    24241 gagtgacact gatttttttt aaaattttct cttttctttt cttggaaata ggtgtataat
    24301 acgtttatta aatttttgag gagttgtcta tgaagaaaag ttttatccat caacaagaag
    24361 aaatttcctt tgtcaaaaac acttttaccc agtatttgaa agataagcta gaagttgtcg
    24421 aagttcaagg tcctatcttg agtaaggtcg gtgacggaat gcaggacaac ctgtctggtg
    24481 tggaaaatcc agtatcggtc aaggttctcc aaatccctga tgctacttat gaagtggtgc
    24541 actcacttgc taaatggaaa cgccacacct tggctcgttt tggctttggt gaaggagagg
    24601 gtctctttgt ccacatgaaa gcccttcgtc cagatgagga ttccttggat gcaacccact
    24661 ctgtttatgt tgaccagtgg gactgggaga aggttatccc aaatggtaag cgtaacatcg
    24721 tttatctaaa agaaacagtt gagaagattt ataaggctat tcgcctgact gagctagctg
    24781 ttgaagctcg ctatgacatc gagtctatct tgccaaagca aatcaccttt atccatacag
    24841 aagaattggt agaacgctac ccagacttga caccgaaaga acgtgaaaat gcgatttgta
    24901 aagaatttgg agccgtcttt ttgattggta tcggtggcga gttgccagat ggtaaaccgc
    24961 acgatggacg tgcaccagac tatgatgact ggacaagcga gtctgagaat ggctacaagg
    25021 gtctaaatgg tgatattctt gtctggaatg agtctttagg tggagccttt gagttgtctt
    25081 ctatgggaat tcgtgtagat gaagaaactc ttagacgtca ggtggaaatt acaggtgatg
    25141 aagaccgctt ggaattggaa tggcacaagt ctttgttgaa tggcctattc ccattgacaa
    25201 tcggtggagg aattggacaa tctcgtatgg ccatgttcct acttcgcaag agacacatcg
    25261 gagaagtgca aacaagtgtt tggcctcaag aagtccgcga tacttacgaa aatattttgt
    25321 agagaatcga accgcaaggt tcggttttct ttctcttttt gtctataatt tggtataata
    25381 aacagtatga aaatcgtatc aggaatctat gggagacgtc ccctcaagac actagaaggc
    25441 aagacaacaa gacctacttc ggataaggtt aggggagcca tttttaacat gattggtccc
    25501 tactttgaag ggggacgagt cttggacctt tatgcaggta gtggtggttt atctatcgaa
    25561 gcagtatcgc gtggcatgtc cagtgctgtt ttggtggagc gagaccgtaa ggctcagacc
    25621 atcgtggctg aaaatatcca gatgaccaag gaagttggaa aatttcaact cctcaagatg
    25681 gatgcagaaa gggcattgga acaggtatct ggggaatttg acctcgtttt cttagaccct
    25741 ccctatacca aggaacaaat cgtagcagat attgaaaaaa tggctgagag agagcttttt
    25801 tctgaagatg ttatggttgt gtgcgagacg gataaggccg ttgaacttcc agaagaaatt
    25861 gcctgtctgg gtatctggaa ggaaaagatt tatggaatta gtaaggtgac agtctatgtc
    25921 agataagatt ggcttattca caggctcatt tgatccgatg acaaatgggc atctggatat
    25981 cattgaacgg gcgagcagac tctttgataa gctctatgtc ggtatttttt ttaatcccca
    26041 caaacaagga tttcttccta tcgaaaatcg taaacggggg ctagaaaagg ctttgggaca
    26101 tctggaaaat gttgaagtcg tggcttctca tgatgaattg gtggtcgatg ttgcaaaaag
    26161 attgggtgct acttgtctag tgcgtggttt gaggaatgcg tcggatttgc aatatgaagc
    26221 cagttttgat tactacaatc atcagctgtc ttctgatata gagactattt atttacatag
    26281 tcgacctgaa catctctata tcagttcatc aggcgttaga gagcttttga agtttggtca
    26341 ggatattgcc tgctatgttc ccgagagtat tttggaggaa ataagaaatg aaaaaaaaga
    26401 ttagatggcc cttatacgtc attgcggcct tgattgtgac tttcttggca tttgtagtgc
    26461 ccttgcctta ttatatagag gttccaggtg gttcggaaga tattcgccaa gtccttaaag
    26521 taaatgacac agaagataag gaagctggtg cctatcaatt cgttacggtt ggtgttcaac
    26581 atgccacttt agctcatatg atttatgctt ggttgacacc ttttacagat attcgtagtg
    26641 ctcaggagac tacaggtggt tcttccgatg ttgaatttat gcgaatcaat caattctaca
    26701 tgcaaacatc acaaaatatg gccaagtatc aaggtctaaa aacagctggt aaggatatcg
    26761 aactcaagta ctttggggtt tatgtcttga atgtgacgga taattcaacc tttaaaggga
    26821 ttctcaatat ctctgatacg gtcacagcag tcaatgatca gacctttgat agttccaaag
    26881 acttgattga ttacgtcagt tctcaaaaat taggggactc cgtcaaggtc acctatgaag
    26941 aggatgggca aaccaagtct gcagaaggaa agattatcac cttggaaaat ggaaaaaatg
    27001 gaattggaat cggcttgatt gatcgtacag aggtaatcag caatgtccca attagctttt
    27061 caacagctgg tattggcggc ccaagtgctg gtctcatgtt tagtctagct atctatactc
    27121 aaatagctca cccagatctt cgtaatggtc gtattgttgc cggtacaggt accattgacc
    27181 gcgatggtaa tgtgggagac attggaggta ttgataagaa ggttgtagct tcggctaggg
    27241 caggtgctgc tattttcttt gctcctgata accctgttag cgaagaagaa caaaaggcgc
    27301 atccggacgc gaaaaacaac taccaaacag ccctagaagc ggctaaaaca atcaagacgg
    27361 atatgaaaat cgtgcccgtt aaaaccctac aagatgcgat tgattacttg aaaaacaatc
    27421 cctaattttt gagtgaagtt tccaaactag cgcacaaaca gagaagatgg tataatagtc
    27481 aaatggttca attattattc actctaagta gtcatatgct ctttatttat gtgagttttt
    27541 accttttaaa ggatcttgtt agatgggaga aggttttaaa agtgacagat gagaatacaa
    27601 gaaaagttcg tttattagta gcctttttta gcattgtcat aggctacatc ctgagttctt
    27661 tctttattag cctgtatcat ttgtggcaag aagcgcttag aggattatta tgaaatcaag
    27721 agtaaaggaa acgagtatgg ataaaattgt ggttcaaggt ggcgataatc gtctggtagg
    27781 aagcgtgacg atcgagggag caaaaaatgc agtcttaccc ttgttggcag cgactattct
    27841 agcaagtgaa ggaaagaccg tcttgcagaa tgttccgatt ttgtcggatg tctttattat
    27901 gaatcaggta gttggtggtt tgaatgccaa ggttgacttt gatgaggaag ttcatcttgt
    27961 caaggtggat gctactggcg acatcactga ggaagcccct tacaagtatg tcagcaagat
    28021 gcgcgcctcc atcgttgtat tagggccaat ccttgcccgt gtgggtcatg ccaaggtatc
    28081 catgccaggt ggttgtacga ttggtagccg tcctattgat cttcatttga aaggtctgga
    28141 agctatgggg gttaagatta gtcagacagc tggttacatc gaagccaagg cagaacgctt
    28201 gcatggtgct catatctata tggactttcc aagtgttggt gcaacgcaga acttgatgat
    28261 ggcagcgact ctggctgatg gggtgacagt gattgagaat gctgcgcgtg agcctgagat
    28321 tgttgactta gccattctcc ttaatgaaat gggagccaag gtcaaaggtg ctggtacaga
    28381 gactataacc attactggtg ttgagaaact tcatggtacg actcacaatg tagtccaaga
    28441 ccgtatcgaa gcaggaacct ttatggtagc tgctgccatg actggtggtg atgtcttgat
    28501 tcgagacgct gtctgggagc acaaccgtcc cttgattgcc aagttacttg aaatgggtgt
    28561 tgaagtaatt gaagaagacg aaggaattcg tgttcgttct caactagaaa atctaaaagc
    28621 tgttcatgtg aaaaccttgc cccacccagg atttccaaca gatatgcagg ctcaatttac
    28681 agccttgatg acagttgcaa aaggcgaatc aaccatggtg gagacagttt tcgaaaatcg
    28741 tttccaacac ctagaagaga tgcgccgcat gggcttgcat tctgagatta tccgtgatac
    28801 agctcgtatt gttggtggac agcctttgca gggagcagaa gttctttcaa ctgaccttcg
    28861 tgccagtgca gccttgattt tgacaggttt ggtagcacag ggagaaactg tggtcggtaa
    28921 attggttcac ttggatagag gttactacgg tttccatgag aagttggcgc agctaggtgc
    28981 taagattcag cggattgagg caagcgatga agatgaataa gaaatcaagc tacgtaatca
    29041 atcgtttact tttagtcatc atagtactga ttttaggtac tctggctcta ggaatcggtc
    29101 taatggtagg ttatggaatc ttgggcaagg gtcaagatcc atgggctatc ctgtctccag
    29161 caaaatggca ggaattgatt cataaattta caggaaatta ggctggagaa ccagcctttt
    29221 tctaaagata aggagaaata tgaacaaaaa aacaagacag acactaatcg gactgctagt
    29281 gttattgctt ttgtctacag ggagctatta tatcaagcag atgcagtcgg cacctaatag
    29341 tcccaaaacc aatcttagtc agaaaaaaca agcgtctgaa gctcctagtc aagcattggc
    29401 agagagtgtc ttaacagacg cagtcaagag tcaaataaag gggagtctgg agtggaatgg
    29461 ctcaggtgct tttattgtca atggtaataa aacaaatcta gatgccaagg tttcaagtaa
    29521 gccctacgct gacaataaaa caaagacagt gggcaaggaa actgttccaa ccgtagctaa
    29581 tgccctcttg tctaaggcca ctcgtcagta caagaatcgt aaagaaactg ggaatggttc
    29641 aacttcttgg actcctccag gttggcatca ggtcaagaat ctaaagggct cttataccca
    29701 tgcagtcgat agaggtcatt tgttaggcta tgccttaatc ggtggtttgg atggttttga
    29761 tgcctcaaca agcaatccta aaaacattgc tgttcagaca gcctgggcaa atcaggcaca
    29821 agccgagtat tcgactggtc aaaactacta tgaaagcaag gtgcgtaaag ccttggacca
    29881 aaacaagcgt gtccgttacc gtgtaaccct ttactacgct tcaaacgagg atttagttcc
    29941 ctcagcttca cagattgaag ccaagtcttc ggatggagaa ttggaattca atgttctagt
    30001 tcccaatgtt caaaagggac ttcaactgga ttaccgaact ggagaagtaa ctgtaactca
    30061 gtaaaagata agcctaaact cctatgtcac ttatggatgt aggagttctt tttactagtt
    30121 taagcagggc tagaataggt actaataaaa aatagtaact tctaaaacta acttccagtt
    30181 tcccacaacc tagcttttag tatgagaaaa acgcgtgaaa tcagtggaaa tccgtcttag
    30241 actaacttcc agttttggga gagagatgga agttacgcta agaaaaaaat aatatgtatt
    30301 ggattaaatt ttgtgatata ataaaggata agatactatt ttaggagaag aactatggaa
    30361 gacccaagta gtcagaattt gttgctacaa tttgttttat tgtttatctt gacggtatta
    30421 aatgcctttt tctcagccac agaaatggcc atggtttctc ttaatcgtgc ccgagttgaa
    30481 caaaaggcgg aagaaggaga cagacgctac atccgcctgc tgaaggtact agaaaatcct
    30541 aaccactttt tatcaaccat tcaggtagga atcaccctga ttacaatctt atcaggggcg
    30601 agtttaactg atactctagg acgtgtgatt gcctcttggc ttgggaatgg cgaaacagca
    30661 caagccgtgg caacttttct atccttggca tttttgacct atatttccat cgtttttggg
    30721 gaattatatc ctaagagaat cgctcttaat ctaaaggatg ccttggcaat tcgtacagcg
    30781 ccgattatca ttgggatcgg aaaactagtc agtccttttg tttggctttt agctgcttcg
    30841 accaatttct tgagccattt gactcctatg tcattcgatg atgcggatga aaagatgacc
    30901 cgtgatgaaa ttgcctatat gctgacaaat agtgaagaaa cattggatgc tgatgagatt
    30961 gagatgctac aaggtgtctt ttcgctcgat gaactgatgg cacgagaggt tatggtgcct
    31021 cgaacggatg cctttatggt ggatattcag gatgatagtc aagccattat ccaaagtatt
    31081 ttaaaacaaa attattctcg tatcccggtt tatgatgggg ataaggacaa tgtaattgga
    31141 atcattcaca ccaagagtct ccttaaggca ggctttgtgg acggttttga caatattgtt
    31201 tggaagagaa ttttacaaga tccacttttt gtacctgaaa ctatttttgt ggatgacttg
    31261 ctaaaagaac tgcgaaatac ccaaagacaa atggcaatct tgctggatga atacggtggt
    31321 atggctggtt tggtgacttt ggaagacctc ttagaggaaa ttgttggtga aattgatgat
    31381 gaaacggaca aagcagcaat agatgttcat cagattggcg aggataccta cattgttcaa
    31441 ggaactatga ccctcaatga tttcaataat tactttgatg ttgaactgga aagtgatgac
    31501 gttgatacca tcgctggtta ttatttgaca ggagtgggaa ctattccaac gactgagaaa
    31561 ctcagctatg aattggtcag ccaaaacaaa cagtttatct taaccaatga taaagtgaag
    31621 aatggacgtg ttaccaaggt aaaagtccaa atcacagaag tcgaaataga agaagaaaca
    31681 gaataaacta gaggcttttg tcaccaggcg tgacgaagct tttttcaatt gatttcaaaa
    31741 gggaattatg ccatggaaag aactctgcca caaactcgct ccaaaagttt ttaaagttat
    31801 acgtatttat tcgagggaaa ataagaaaag cccttcaaat tgggctttct gttcatttga
    31861 aacctgataa atcaagttat agaaggcggt agacggattt gaaccgacga tcaagctttt
    31921 gcagagccgt gccttaccac ttggctatac cgccttaacg tttattatta taccttgaaa
    31981 atgattttca gtcaatagtt ttttcagttt tttgtaccat agcgtgattc gaatgtgatg
    32041 ccaagttttc tatgggaaaa aatttaccaa aaacctactg aaaccccttg aaaaatctag
    32101 ctaaataggg tataatatgg gtaatcattt gtcgtaggtt ttgtctgaaa tattgtccag
    32161 acaaggctca cagcagttaa atcttctgaa aaagtcagat ttagctgctc tttttgtgct
    32221 ttttttcaag attatgagca tttgtaacag aggcttaaag attctgaaaa ttcgtcaaga
    32281 ggacacggtg ataaggggtt tacaaccata tgacgattag aaaagcctga ttgacaaggc
    32341 ttggaactta tttacaaagg agaatcatct tggcaggaca tgacgttcaa tacgggaaac
    32401 atcgtacccg tcgtagtttt tcaagaatca aagaagttct tgacttacca aatttgattg
    32461 aaattcaaac tgactcattc aaagctttcc tagaccacgg tcttaaggaa gtgtttgaag
    32521 atgtattgcc aatttcaaac ttcacagaca caatggagtt ggaatttgtt ggatatgaaa
    32581 tcaaggaacc aaaatacacg ctagaagaag ctcgtatcca cgatgctagc tactcagcac
    32641 caatttttgt aaccttccgt ttgatcaata aagaaacagg cgaaatcaag acccaagaag
    32701 ttttctttgg tgatttccca atcatgacag aaatgggtac tttcatcatc aatggtggtg
    32761 aacgtattat cgtttctcag ttggtccgct caccaggtgt ttactttaac gacaaagtag
    32821 acaaaaatgg taaggtgggc tatggttcaa ctgttatccc taaccgtgga gcttggttgg
    32881 aacttgaaag cgactcaaaa gatatcacct acactcgtat cgaccgtact cgtaagattc
    32941 catttacaac cttggttcgt gctcttggtt tctcaggtga tgatgaaatc tttgatatct
    33001 ttggtgacag cgaattggtt cgcaacactg ttgaaaaaga tatccacaag aatccaatgg
    33061 actctcgtac agacgaagcc ttgaaagaaa tttacgaacg ccttcgtcca ggtgagccta
    33121 agacggctga aagctcacgt agcttgcttg tagctcgctt ctttgaccca cgtcgttatg
    33181 acttggcagc agttggtcgt tacaaaatca ataaaaaact caatgttaaa acacgtttgc
    33241 tcaaccaaac cattgcagag ccattggtag accctgaaac tggagaaatc ttggtagaag
    33301 ctggtacgat tatgactcgt agcgtgattg aaagcattga aagccatttg gatggcgact
    33361 tgaacaagat tgtctacatc ccaaacgatg cagccgttgt gactgagcct gttgttcttc
    33421 aaaaattcaa ggttattgct ccaactgatc cagatcgcgt cgtaacgatc attggtaatg
    33481 ctaacccaga tgacaaggtt cgtacggtga ctcctgcaga tatccttgct gagatgagct
    33541 acttcctcaa cttggctgaa ggacttggcc gtgtagatga tatcgaccac cttggaaatc
    33601 gtcgtatccg tgcggttggt gaattgcttg ccaaccaagt acgtttggga ctttctcgta
    33661 tggaacgtaa tgtccgtgaa cgtatgtctg ttcaggacaa tgaagtcttg acaccacaac
    33721 aaattatcaa tattcgtcct gtaacagctg cagttaaaga attctttggt tcatcacagt
    33781 tgtcacagtt catggaccaa cacaacccgc tttctgagtt gtctcacaaa cgccgtttgt
    33841 cagccttagg acctggtggt ttgactcgtg accgtgccgg atatgaagtg cgtgacgtgc
    33901 actacactca ctatggtcgt atgtgtccaa tcgagacacc tgaaggacct aacatcggtt
    33961 tgatcaataa cttgtcatct tacggacact tgaacaaata tggttttgtt caaacaccat
    34021 accgtaaggt tgaccgtgaa acaggtgttg tcacgaacga aattgtttgg ttgacagctg
    34081 atgaagaaga tgaatatact gtagctcagg ctaactctcg tctgaatgaa gatggaacct
    34141 ttgctgagaa gattgtcatg ggacgtcacc aaggggtcaa ccaagagtat ccagctaata
    34201 ttgttgacta catggacgtt tcaccaaaac aggtagttgc cgttgcgaca gcatgtattc
    34261 ctttcttgga aaacgatgac tccaaccgtg ccctcatggg agccaatatg caacgtcagg
    34321 ctgtgccatt gattaatcct caggcacctt acgttggtac tggtatggaa taccaagcag
    34381 cccacgattc tggtgcggct gtgattgctc agtatgatgg taaagttact tacgcagatg
    34441 ctgacaaggt agaagttcgt cgtgaagatg gttcattgga tgtttaccac atccaaaaat
    34501 tccgtcgttc aaactcaggt actgcttaca accaacgcac tctcgtaaaa gttggtgatg
    34561 tcgttgaaaa aggcgatttc atcgctgacg gaccttctat ggaaaatgga gaaatggcgc
    34621 ttggacaaaa cccaatcgtt gcctacatga cttgggaagg ttacaacttc gaggatgccg
    34681 ttatcatgag cgaacgcttg gtgaaggacg atgtctacac atctgttcac cttgaagaat
    34741 acgaatcaga aacgcgcgat acaaagcttg ggcctgaaga aatcactcgc gaaattccaa
    34801 acgttggtga agatgccctc aaagaccttg acgaaatggg gattatccgt attggtgctg
    34861 aggttaaaga aggtgatatt cttgtaggta aagtaacacc taagggtgag aaagatcttt
    34921 cagctgaaga acgtctcttg cacgctatct ttggagacaa gtctcgtgaa gtgcgtgata
    34981 cttctcttcg tgtaccacac ggtgccgatg gtgtcgttcg tgatgttaag atctttacac
    35041 gtgtaaatgg agatgagttg caatcaggtg ttaacatgtt ggttcgtgtt tacatcgctc
    35101 aaaaacgtaa gattaaggtc ggagataaaa tggccggacg tcacggaaac aaaggggttg
    35161 tctctcgtat cgttcctgta gaagacatgc cttaccttcc agacggaact ccagtcgaca
    35221 tcatgttgaa cccacttggg gtgccatcac gtatgaatat cggtcaggtt atggagcttc
    35281 accttggtat ggcagctcgt actcttggta ttcacattgc gacaccagtc tttgatggag
    35341 caagttctga agatctttgg tcaactgtta aagaagcagg tatggatagc gatgccaaga
    35401 caatccttta cgatggacgt acaggtgaac catttgataa ccgtgtttct gttggagtca
    35461 tgtacatgat caaactccac cacatggttg acgataaatt gcatgcgcgt tcagtcggac
    35521 cttactcaac tgttacccaa caaccactcg gaggtaaagc tcagtttggt ggacaacgtt
    35581 tcggtgagat ggaggtttgg gctcttgaag cctacggtgc gtcaaatgtc cttcaagaaa
    35641 tcttgactta caagtcggac gatatcaacg gacgtttgaa agcctatgaa gctattacaa
    35701 aaggcaaacc aattccaaaa ccaggtgttc cagaatcctt ccgagttctt gtcaaagaat
    35761 tgcaatctct tggtcttgac atgcgtgtcc tagacgaaga tgaccaagaa gtggaacttc
    35821 gcgacttgga tgaaggaatg gacgaagatg tcatccacgt agatgacctt gaaaaagccc
    35881 gcgaaaaagc agcccaagag gctaaagcag cctttgaagc tgaagaagct gagaaagcaa
    35941 caaaagcgga agcaacagaa gaagctgctg aacaagaata agcagttcac ttagaataga
    36001 aagggaagaa atagtggttg atgtaaatcg ttttaaaagt atgcaaatca ccctagcttc
    36061 tccaagtaaa gtccgttcat ggtcttatgg agaagtcaaa aaacctgaaa caatcaatta
    36121 ccgtaccttg aaaccagaac gtgaaggact ctttgatgaa gtgatctttg gtcctacaaa
    36181 agactgggaa tgtgcttgtg gtaagtacaa acgcattcgt tacagaggaa ttgtttgtga
    36241 ccgctgtggg gttgaagtaa cgcgtacgaa agttcgtcgt gagcgtatgg gacatatcga
    36301 gttgaaagct cctgtatctc acatctggta cttcaagggg attccaagcc gtatgggctt
    36361 gacccttgat atgagccctc gtgccctcga ggaagttatc tactttgcgg cttatgtggt
    36421 gattgatcct aaggatacac cacttgagca caagtctatc atgacagagc gcgaataccg
    36481 agagcgcttg cgtgaatatg gttatggttc atttgttgcc aagatgggtg cggaagccat
    36541 ccaagacctt ttgaagcaag tagatcttga aaaagaaatt gctgaactca aagaagaatt
    36601 gaaaacagct actggacaaa aacgtgtcaa agccatccgt cgtttggatg ttttggatgc
    36661 cttttacaag tctggaaaca aacctgaatg gatgattctt aacatccttc cggttatccc
    36721 accagatctt cgtccaatgt tgcagttgga tggtggccgt tttgcctcat ctgacttgaa
    36781 tgacctttac cgccgtgtta tcaaccgtaa caaccgtttg gctcgtttgc ttgagttaaa
    36841 tgcaccaggt atcatcgttc aaaatgagaa gcgtatgctt caagaagcag ttgacgcttt
    36901 gattgacaat ggtcgtcgtg gtcgtccaat cacaggacca ggtagccgtc cattgaaatc
    36961 attgagccac atgcttaaag gtaaacaagg acgcttccgt caaaacttgc tcggtaaacg
    37021 tgttgacttc tcaggacgtt ccgttatcgc cgttggtcca actcttaaga tgtaccaatg
    37081 tggtgtgcca cgtgaaatgg cgattgaact ctttaaacca tttgtcatgc gtgaaatcgt
    37141 tgcccgtgat atcgtgcaaa acgtcaaagc agctaaacgc ttggtggaac gcggagatga
    37201 gcgtatctgg gatatccttg aagaagtgat taaagaacac ccagtgcttt tgaaccgcgc
    37261 accgaccctt caccgtttgg gtatccaagc cttcgagcca gtcttgattg atggtaaggc
    37321 tcttcgcttg cacccacttg tctgtgaagc ctacaatgct gactttgacg gggaccaaat
    37381 ggccatccac gtaccacttt cagaagaagc acaagcagaa gctcgtatcc tcatgctagc
    37441 tgctgagcac atcttgaacc cgaaagatgg gaaaccggta gttactccat ctcaggacat
    37501 ggttttgggt aactactact tgaccatgga agaagctggt cgcgaaggtg aaggaatggt
    37561 cttcaaagac cgtgacgaag cggttatggc ttaccgcaat ggttatgttc acctccactc
    37621 acgtgttggt atcgcaacag acagcctcaa caagccttgg acagaagagc aaagacataa
    37681 ggtcttgctt acaacagttg gtaaaattct cttcaacgat atcatgccag aggggctacc
    37741 atacttgcaa gaaccaaaca atgccaactt gacagaaggt gttccagcta aatacttctt
    37801 gccacttggt ggagctatca aggaagctat cagcaatctt gagctcaacc ctccattcaa
    37861 gaagaaaaac ctcggaaata tcatcgctga aatcttcaaa cgtttccgta cgacagaaac
    37921 ttctgcccta cttgaccgca tgaagaacct cggttaccac cactcaactc ttgcaggatt
    37981 gacagtgggt attgccgata tcccagttgt tgatgacaag gctgaaatca ttgaagaatc
    38041 acacaaacgt gtcgaacaaa tcaccaaaca attccgtcgt ggtatgatca cagacgacga
    38101 gcgttacaat gctgttacag ctgaatggcg tgctgcccgt gaaaaacttg agaaacgctt
    38161 gattgctaat caagatccta agaacccaat cgttatgatg atggactctg gagcccgtgg
    38221 taacatctca aacttctcac agcttgccgg tatgcgtggt ctgatggctg ctccgaatgg
    38281 acgtatcatg gaattgccaa tcctttcaaa cttccgcgaa ggtttgtcgg tattggaaat
    38341 gttcttctca actcacggtg ctcgtaaagg tatgaccgat acggccctta agacagccga
    38401 ctcaggttac ttgactcgtc gtttggtcga cgttgcccaa gacgttatca tccgtgagga
    38461 cgactgtgga actgaccgtg gtctcttgat ccgttctatc gcagaaggaa aagagatgat
    38521 cgagtctctc gaagagcgtc tcaacggtcg ttacactaag aaaactgtta aacatccaga
    38581 aactggtgca gtgattattg gtccaaatga attgattaca gaagacaagg cgcgtgaaat
    38641 tgtcaatgct ggtgtggaag aagtgactat ccgttctgta tttacatgta acactcgtca
    38701 cggtgtctgc cgtcactgtt acggtatcaa cttggcgact ggtgatgcgg ttgaagttgg
    38761 tgaagcagtt ggtacaatcg ctgcccaatc tatcggggaa cctggtacac agcttacaat
    38821 gcgtaccttc cacacaggtg gggttgcctc aaataccgat atcactcagg gtcttcctcg
    38881 tgtccaagaa atctttgaag cccgcaatcc taaaggggaa gcggttatta cagaggttaa
    38941 aggacaagtt actgctatcg aagaagatgc atcaactcgt accaagaaag tctttgttaa
    39001 gggtgaaact ggcgaaggtg aatatgtcgt tccatttaca gctcgtatgc gtgtcgaagt
    39061 tgggggccaa gtagcgcgtg gtgctgctct gacagaaggt tctatccaac caaaacgtct
    39121 ccttgcagtt cgtgatgtct tgtcagttga aacgtacctt ctcggtgaag tacaaaaagt
    39181 ttaccgtagc caaggggtag aaatcggtga caaacacatc gaggtaatgg ttcgtcaaat
    39241 gatccgtaaa gtccgtgtca tggatccagg tgatacagat cttctcatgg gtaccctcat
    39301 ggatatcaat gactttacag atgccaacaa agatgtcctt atcgcaggtg gagttccagc
    39361 gacaggtcgc ccagtcctta tgggaattac caaagcctca cttgaaacaa acagtttctt
    39421 gtcagcggct tccttccagg aaacaactcg tgtccttact gacgcagcta tccgtggtaa
    39481 gaaagaccat ctccttggac ttaaagaaaa tgttatcatc ggtaagatca tcccagctgg
    39541 tactggtatg gcccgttacc gtaaccttga accacatgct gtcaacgaag aagaatacct
    39601 taatcctcca gtagaggaag aaggaaatga agaaacaaca gaagtagttg tggatactgc
    39661 cgttgaaact gtggaagaaa cagtagaata agagagaatg agagaacccg agggttctct
    39721 cattctctct tctgaaaact ttctccattt ttccacgaaa tgtggtaaaa taaaagaaag
    39781 aagctgacaa aggagacggg tatggaacaa acattcttta tcatcaaacc agatggtgta
    39841 aaaagagggc tagtgggtga agtgttaaag cgcatcgaac aacgtggatt tacaatcgaa
    39901 aaattggagt ttcgttcaca ggtttcagaa gagttgattg accagcacta tcaggacttg
    39961 gttggtcaga gtttttaccc accgattcgt gaattcatga cttcaggtcc agttcttgtg
    40021 ggtgtcattt ctggtcccaa agtaatcgaa acttggcgga ccatgatggg tgcaactcgt
    40081 ccagaagaag ctttaccagg cactattcga ggtgattttg caaaagctgc tggagaaaat
    40141 gagattatcc aaaatgttgt acatggttca gattcagaag agtcagctaa gcgagaaatt
    40201 gctctttggt tttaagagtg gattggctca atcaattggt taaaagctca tttgaataga
    40261 aagtatagtc aattagttta agacatgacg catgatatca aactttttag tttttgatat
    40321 ggtgcgtttt ttgattaagt gactattagt ttgtctcgct ccgttaggtg cgagacaaaa
    40381 aaaacacccg ctatgcgggt gtgcgtcgaa ggttatacca aaaaaactcc aaacgcgata
    40441 caataaaggt gttcaatcca attgtaaagc gaaaggagaa aaatatggca caaaaggttc
    40501 ttttatcctg ttcttgtttc aattgactat atttctatac tttttcttcc tttctctgtg
    40561 aaaatcgcaa gtttttccca ccttttctca atactgaaac aacatctttc cagaacttca
    40621 ataatttctt tttgtgttaa atcattattt aactaaatct ttggaggcaa tacgttttca
    40681 aagcgacttt tttaccatag gttttgagcc ttcaacacag attactaagc caaaaatgct
    40741 ctaaattttt gaaattctaa caaattccac tcaactttat catcatcttt gactttcaca
    40801 atatcttcct caaaataaca tggaataaag atagttttct tttgaaacgg ttgtaggagg
    40861 aaaatctctc ctacactatt attgattctg agaggaaatt gcaaaatatc atctaccaaa
    40921 ttttcaatta ttaagatttt ttgcagttta tctgaattag aatcgcaagg cttctcaata
    40981 atataattgt cgaatttttt cattctaact tcctctctac tatttcttcc tttatcaaga
    41041 aaaagttacc tcaatattaa taaagtacaa ttctaaatta actccaattc ttgattcatg
    41101 ataatatttc agtaactcat cgtgcaatta aaaacaagga tttttatttc agacgatcca
    41161 tcgtgaacac ttcatcagcc atctcccaaa ttgccggatt atgtgttgcg ataatgatta
    41221 gcctattatc atctcgaaga gatagcaaaa tctccataat caactgagaa gttgctgggt
    41281 ctattgaagc tgttggctca tctgccagaa taaagggtgg attctttaag ataacttttg
    41341 ccaaggcaac ccgttgcgat tctccgcccg ataactcaaa gatgcgctta tctaggttaa
    41401 gataagccag gccgacctgt tctaaagcct gcttctgcct caaccgctgt tccgaccgac
    41461 tcaacttttg accaatgaga cctagcttaa ggttttcttc aatactttgg ttttcaatta
    41521 agccaaagtt ctggaagagg tagcccaatt cgtgacggaa aaaatcactc gatttataat
    41581 tggccaagtc tttacctcgg taaaaaatcg tcccatcata aggttctaat ttcccaatca
    41641 tgttcatcaa ggttgttttt ccgctaccac ttgaaccaat taaggcatag acttttccag
    41701 cctcaaatgt cattgaaaga ttcgaaaata actctcgttc tccaaaagat ttactcacct
    41761 gtttaagttc aatcatatta acctcccttc aaaacaagca tggacatctt gttttctttc
    41821 tgcatttgga catgtaactg taaaagagat agaccagtaa agagtaacaa gactaagaaa
    41881 gcaactccta tctctacctg aagaaataca ctcgcaacaa atcccagtaa aaacacaccc
    41941 agttgagcaa agagataagt gcgatggatt tctaagaacc tgagacctgc aatgcgtttg
    42001 ataaaaatgg cacgtctaaa ttcttcaaag tagagcctat tcatagtgtt aaacagcaag
    42061 attgaagttg caatcccaag cacagctcct gctagcatta cccaacgttc cctctggata
    42121 ttatccaata atgtgatgta gttgtggtaa cctgtttgca tttctgagac ccaattttca
    42181 atgccttgtc tctggataag ctcctgggca tcagacaatt gattaaagag aacgtagttc
    42241 tgtactgcgt ctatccaaaa caaaatggac tgtggaccag ttgattgggg tgttataaca
    42301 atgatgattg gatctttcaa aaactgctgg taagaaatag gggtcgtatt atacacaaaa
    42361 cgatcctgac ctgattctaa ataacctacc gtagcagtca tttgctgtcg ttcatcttga
    42421 ctagacatgc gactggttaa gtcgtcttca aaaacagatt tataatgttc ttcctctgaa
    42481 cggaggtgtt caggcagcaa taagacaaac tcccctacat taaggtgatt catcttttgc
    42541 ttaatagttg tatctacagg aatgttttga cgctccaagt aatgcggtgt gacgataagg
    42601 acattgccat tcgggctgta atcgtgccat tctgtagagg ttgtcaagtt tttggaggaa
    42661 gccatgccat tttgcaaagt acggtcaatt aactggtgtc tagataagaa agccttttgt
    42721 tctgaaacag ccagatccat caattgatac caagttctga gtttcctttg agcttgttca
    42781 tcaaaaccag gactcgttcc ttcacggctg attgataggg taatcagttg tctttcctga
    42841 ctccaaacct cttgtccaat ccgatgctgt tgccaggctt gggaatactt taagctactc
    42901 cctattccca gcgttacaat aataatcgct aacagttgac cgattaaaat caaactaatg
    42961 attcctctga caggcacttg cccttttata atctgcatca ggtgtatctt ttttatccca
    43021 actgcgaaga gttgagcgaa aaacagggag atcgacaaca agatgagatt ataactgagc
    43081 aagcctgctc ctatggtcat tagggattgc gttggaagcg acagaatttt ttgcataaga
    43141 atggcgagca cgccagctaa actgaaacca acagctatcc ctttcaaatc ctcaccaact
    43201 ggtctaagga aaatggacca ccgtttctct cctgaaatga ggcgaatgcc cgatgaccgt
    43261 aattggctaa tttgactaat taaagtcagt gctacaaagg ttaagatgaa aatcaataga
    43321 ctgattaact gaaatccgtt actaaagata gccattaacg tagatagttt agatggaatt
    43381 gtcaggtgca tgttagtcaa gccaagttga cttagctctt cccttagcaa gtgaatatct
    43441 aggtgtccat cgaatacaaa atagtttgtt tcaacactac tactttgagc atcttctaga
    43501 tttttttcct gaagcccatc aggcaacttt ccgtccccaa aggtcgtata agaaaaaact
    43561 gtagtacctt ctgagttagg atcttggtgt tgaatcgcaa taaagctatc tgtttcttct
    43621 gctagttttt ccaagcgtgt agcaacatgc tgaaaagttg tttcagggga agaatcacgt
    43681 acaacaacgt tggggtaata atgggagaca tatgtatcag tccaaatggt aaatacccaa
    43741 acaaagaaca aactagcaag caggttggat atgagtataa ataatttttt catagtgcat
    43801 tccttattct aaaacagagg gcagaaatac tcctgccctc tataaactaa caagcttact
    43861 gaattattga taaaagaatc ttcttcaatt attctttacc atcccgcatc aaatgtaact
    43921 tgctccccaa aatttgtatt aacaaacgca taggccgcac tacgtgctcc tgcataaact
    43981 gttttttgat tgttacgtcc attacttcca acataggccc agtgatactg tgaaccatga
    44041 taataattcg aaaatgctcc ccaattattt ggatcatgat ggcctccata ggtccactcg
    44101 ccaccacggt gagaaactgc caaaacagga agagccaaac taaatgccaa aacggcaagg
    44161 gatgatgcaa ctacttttct aaattttaac atattattac tcctctgaat gaaatattat
    44221 gaaaatgagc gaaatgcaac tatatatttt aattagaaat ctcagtctga attatagtat
    44281 cctatttttt cctcctttct aactgcacgt tcctttctac aggcagagac ctaattttat
    44341 aaaccaatct taaatacttt agattttgta actcataatt ttcaacagtt ggttagctat
    44401 gaaagcattt tatcaaacat ctccattctt atatctatct ggtattgtta caagctctca
    44461 tcagaatacc tttctctaaa tagttgaatt ttaaagtaat ataaaatcaa tcagccttcc
    44521 caacatcaag accattggac ttcttttgcg attgcactcg aatctccaat tgtttattct
    44581 tctgaataaa ctgttggtaa ggaattgtat tactaaacat aaaaacacct agcaatgcaa
    44641 atgtaactaa ttttttaatt ccacgttttt tccatgcaat gaaacccctt tctttttatt
    44701 ctaacagata tattttattt agtcaagtgt ttttattata ttttgaactt ttttattatt
    44761 actatagaga attatttatt cctttaactt gctattttga actaaaaatt ttataatgaa
    44821 attaagcaaa caggaaggtt tattatcttt aatgaataca ctcgcagaga aattcagatt
    44881 gaaaagaaaa gagttgagac tctcccagca aactcttgca gaaggaattt gtgaacaaag
    44941 ccagattagt aaaattgaga gagggcattt cattccctcc gcagaccttt tgttcaaact
    45001 ctcacaacga cttgaagtgc cattagatta tttttttaat gaacaaattg aaattaaatc
    45061 taacctctct aatttcaagc aattatctgc tcgcctatta gatgatagaa attatgaaaa
    45121 tttggaatat atttatagaa tagagattga acgaagtact tttctaacac tagaagaccg
    45181 aacttacctt gaatggatta aatctataat tgacttctat caatatgaca gtaagtgtga
    45241 agcaatttct tcattggaaa atatattatt aaaagtctct tcaaatactc tgatttattt
    45301 aaaggcgttg aatactctat ctaatttcta ttccttagtg ggtcgtgaac aagaatatga
    45361 ggcaaactac tctcatttaa tagagttgta tcagacaaaa aatttggacc atcaagagtt
    45421 tttatttggc tacatcagag ttcgttacaa ctacgctcac tacctagtat caaaggaaaa
    45481 atataatgaa gccatccaag aagctcttga aacgattgaa ctctgtaaac aaagacagac
    45541 aagctaccaa ttggctcctc tacttattct tgtaggaaat gctggagcca aatttctaga
    45601 cagagaacaa gtcaaaaatt attatataga agcaagagag ttatgtaaga tttataacaa
    45661 tcctttaatg ttgatgaaga tagaaaatta tttgaaggaa ctagatactg tttagttaat
    45721 cttgacatta tagtttttct gaaacgttaa ataacctgta aggctgatag ttagattaat
    45781 actatcagcc ttataattat gtgactctga gtccgtctcg ctccgtgagg tgcgagacaa
    45841 aacaaccacc cgtttgacgg attttcatga tttcaaattt atattcttcg aaaatctctt
    45901 caaatcacgt cagctctatc tgcaatctca aaacagtgtt ttgagcaacc tgtggctagc
    45961 tacctagttt gatctttgat tttcattgag tattagtctc tagtgtttgt ttagcgtctt
    46021 aaagagacat ttgagaagat tagaaacagt tctctctttt ctcctagtat aatgattggt
    46081 aggaagggag agagaagatg aaatcaatga gaatcttatt tttgttagct ttaattcaaa
    46141 tcagtttgag tagctgtttc ttatggaagg aatgcatctt gtcctttaaa caaagtacag
    46201 cttttttcat cggaagcatg gttttcgttt caggaatctg tgctggagta aattatcttt
    46261 atacccgtaa gcaagaagtc catagtgtcc tagccagtaa gaagtcggtg aagctttttt
    46321 acagtatgtt actcttaatt aatttgttag gagctgttct tgttttgtca gataacttgt
    46381 tcatcaaaaa tacgctgcag caagaattag ttgacttttt attgccatcc ttctttttcc
    46441 tatttgggct agatttgctg atttttttac ccttgaaaaa atacgtgcgc gattttcttg
    46501 ctatgctaga cagaaaaaag acagtgttgg tgactatttt agcaacactt cttttcttaa
    46561 gaaatccaat gaccattgtc tcacttctga tttatattgg actgggcttg ttttttgcag
    46621 cctatcttgt cccaaattcg gttaagaagg aagtttcctt ttatggtcat attttccgag
    46681 atcttgtatt ggtcattgtt acgctcattt tcttttagag aaagcctgtt ttttatggat
    46741 gttatgatga taagtttagt aggaaaatag acacaaaaga aaagtttttg gtataataag
    46801 agtatgtaca taaaaaatga agaagagttg caagccttag gggagcgttt gggccatcta
    46861 ttagcaaaga atgatgtttt aatcttaatt ggagaactgg gtgcaggtaa aacgaccttt
    46921 actaaaggac ttgcaaaagg attacagatt tctcaaatga ttaaaagtcc tacctatact
    46981 atcgtgagag agtatgaagg tcgacttcca ctttatcacc tagatgttta tcgtattgaa
    47041 ggagatgctg attctatcga cttggatgag tttatctttg gtggcggcgt gactgttatt
    47101 gagtggggaa atctcttagg agatgccttg ccagatgctt atttagaatt ggaaattcta
    47161 aaagaagcag atggacgccg tttaaatttt caggcaaagg gtttgcgtgc tgagaaattg
    47221 ttagaggagc ttcaatatgg agtatgaatt gctcattagg gaagcagagc ccaaagatgc
    47281 agctgaatta gtggcctttt taaatcgtgt gagtttggag acagacttta ccagcctaga
    47341 cggagatggt attctcttga ctggtgagga gatggaaata ttcctcaaca agcaagctag
    47401 ttcggacaat cagataacct tacttgcatt cttaaatggc aaaattgctg gtattgtaaa
    47461 tattacagct gaccagcgta agagagtccg tcatattgga gatctcttca ttgtgattgg
    47521 aaaaagatat tggaataatg gcttgggaag tttgttacta gaagaagcga tagagtgggc
    47581 acaagcaagt ggcattctgc gtcgtctcca actgactgtc caaactcgta atcaagcagc
    47641 agtccatctt tatcaaaagc atggctttgt cattgaaggt agccaagagc gtggggcata
    47701 tatagaagaa gggaaattta tcgatgttta cttgatgggt aaactgatag gttagtagaa
    47761 atatggttaa aaaaattatt ggaatggtgc tagctttact ttctgtaact gtagtaggag
    47821 taggtgtttt tgcttatact atttatcaac aagggacaga aaccttagct aaaacctata
    47881 aaaaaatcgg cgaagaaacc aaggttattg aagcgactga acctctaacc attctgttaa
    47941 tgggagtgga caccggaaat gctgaacgaa ctgaaacttg ggtcggtaga agtgatagca
    48001 tgatcttgat gacagtgaat cctaaaacga aaaaaacaac aatgatgagt ttagagcggg
    48061 atattctgac gcgcattgaa tcagggaatg gtcaggctca tgaagcgaaa ctgaactcag
    48121 catatgcaga tggtggagca gagcttgcta tagaaaccat tcaaaaaatg atgaatatcc
    48181 atattgatcg ctatgtaatg gtcaatatga gagggttgca aaaactagtg gatgcagtag
    48241 gaggtattac agtcaataat atcctaggtt tcccaatttc tatcagtgac caagaagaat
    48301 ttaatactat ttctatcggt gttggggagc aacatattgg gggagaagaa gccctagtct
    48361 atgcacgaat gcgttaccaa gatcctgagg gggattatgg tcgtcaaaaa cgtcaacgtg
    48421 aagttattca aaaagtcatg gaaaaagctc tcagtttaaa tagcgttggt cattatcaag
    48481 agattctaaa agctttgagt gacaatatgc agaccaatat tgatttgtct gcaaaaagta
    48541 tccctaactt gctaggctat aaagattcat ttaaaaccat tgaaactcag cagttgcagg
    48601 gtgaaggaga gatacttcaa ggtgtttctt accagattgt ttcgagagca catatgttgg
    48661 aaatgcaaaa tatactccga cgttctttgg gacaagaaga agttactcag cttgaaacca
    48721 atgcggtttt atttgaagat ttatttggca gagcacctgt tggtgatgaa gataattaac
    48781 ttttgataca aataaaaaaa tcaatcgtag gaaaattcct gcgatttttt caaaaaaata
    48841 cgaatagata ggtaggagga aacatgaaag cagaaatcat tgctgttgga acagagattt
    48901 tgacaggaca gattgtcaac accaatgccc agtttttgtc ggaaaaacta gctgagattg
    48961 gggtagatgt atattttcag acggctgtag gagacaatga agttcgtctc ttgtctttgc
    49021 ttgagattgc cagtcaacgt agcagtctgg tgattttgac aggcggtttg gggccaactg
    49081 aggacgacct aaccaaacaa accctagcta aatttttagg aaaagcatta gtctttgatc
    49141 ctcaggctca ggagaagttg gatatctttt ttgccctgcg accagactat gcccgaacac
    49201 cgaataacga aagacaagct caaattgtag aaggagcgat tccactgcca aacgaaacag
    49261 gactggctgt tggaggaaaa ttagaagtag acggagtgac ctatgtcgtc cttccaggtc
    49321 cgccaagtga attgaaaccc atggtcttaa accaacttct acccaagttg atgacaggga
    49381 gcaagctgta ttcccgagtt cttcgtttct ttgggattgg cgagagccag ctggttacga
    49441 ttttggctga tttaattgat aatcagatcg atcctacctt ggccccttat gccaagacag
    49501 gagaagtcac tctacgtctg tcaacaaagg ctagcagtca agaagaggcg aatcaagcgc
    49561 tggatatctt ggaaaatcaa atcttggact gccagacttt cgaaggaatt tctttacgag
    49621 acttttgcta tggttatggg gaagaaacta gtttagccag cattgtggta gaagaactga
    49681 aaaggcaagg gaaaaccatc gcggctgcag agagtttgac ggcaggtctt ttccaagcta
    49741 ccgtgacgaa tttttctgaa gtttcaagta tatttaagag tggttttgtg acctatagct
    49801 tggaggaaaa atcaaggatg ttggatattc ctgccaagaa tttggaagaa catggtgtgg
    49861 tgtctgaatt tacagctcag aagatggctg agcaggcacg aagcaagacc cagtctgatt
    49921 ttggaattag tttgactgga gtggcaggac cagatagcct agaaggacac ccagttggga
    49981 cagtcttcat aggcttggcg caagagcagg gaactgaggt tatcaaggtt aatattggag
    50041 gcagaagccg agcagatgta cgtcacattg cggttatgca tgcctttaac ctagttcgca
    50101 aggctttatt aagtgactaa cttttgatat aatagtagat aggtctgagg atcattagaa
    50161 tgtaggagaa tagaatggcg aaaaaaccaa aaaaattaga agaaatttca aaaaaatttg
    50221 gggcagaacg tgaaaaggcc ttgaatgacg ctcttaaatt gattgagaaa gactttggta
    50281 aaggatcaat catgcgtttg ggtgaacgtg cggagcaaaa ggtgcaagtg atgagctcag
    50341 gttctttagc tcttgacatt gcccttggct caggtggtta tcctaaggga cgtatcatcg
    50401 aaatctatgg cccagagtca tctggtaaga caacggttgc ccttcatgca gttgcacaag
    50461 cgcaaaaaga aggtgggatt gctgccttta tcgatgcgga acatgccctt gatccagctt
    50521 atgctgcggc ccttggtgtc aatattgacg aattgctctt gtctcaacca gactcaggag
    50581 agcaaggtct tgagattgcg ggaaaattga ttgactcagg tgcagttgat cttgtcgtag
    50641 tcgactcagt tgctgccctt gttcctcgtg cggaaattga tggagatatc ggagatagcc
    50701 atgttggttt gcaggctcgt atgatgagcc aggccatgcg taaacttggc gcctctatca
    50761 ataaaaccaa aacaattgcc atttttatca accaattgcg tgaaaaagtt ggagtgatgt
    50821 ttggaaatcc agaaacaaca ccgggcggac gtgctttgaa attctatgct tcagtccgct
    50881 tggatgttcg tggtaataca caaattaagg gaactggtga tcaaaaagaa accaatgtcg
    50941 gtaaagaaac taagattaag gttgtaaaaa ataaggtagc tccaccgttt aaggaagccg
    51001 tagttgaaat tatgtacgga gaaggaattt ctaagactgg tgagcttttg aagattgcaa
    51061 gcgatttgga tattatcaaa aaagcagggg cttggtattc ttacaaagat gaaaaaattg
    51121 ggcaaggttc tgagaatgct aagaaatact tggcagagca cccagaaatc tttgatgaaa
    51181 ttgataagca agtccgttct aaatttggct tgattgatgg agaagaagtt tcagaacaag
    51241 atactgaaaa caaaaaagat gagccaaaga aagaagaagc agtgaatgaa gaagttacgc
    51301 ttgacttagg cgatgaactt gaaatcgaaa ttgaagaata agctgttaaa gcagtggaga
    51361 aatccgctac tttttcgatt tttgattcaa gtttttagat tatatatagt agcttgaaat
    51421 aagatatgaa caactttatt aggaaagtca aattaatttc tagaaatgtt ttagcagcta
    51481 cagcgtacta ttccaaactc aaccaactat aatagatcga aactagaata gtacacatct
    51541 acttctaaaa cattgttaaa aatcgatttg actgtcctta tttcattccg ctatatataa
    51601 gtttgctgtt tcttgtcgct cctctggaaa gctgatataa tagctttatg aataaaaaac
    51661 gaacagtgga cctgatacat ggtccgattc ttccctcgct cttaagcttc acctttccaa
    51721 tcttgctatc aaatattttt caacagctct ataacactgc tgatgtcttg attgttggac
    51781 gatttcttgg tcaagaatcc ttagctgcag taggagcgac gacagcgatt tttgacctga
    51841 ttgtaggttt tacacttggt gttggcaatg gcatggggat tgtcattgct cgttattatg
    51901 gggctcggaa tttcactaaa atcaaggaag cagtagcagc cacctggatt ttaggtgctc
    51961 ttttgagcat tctagttatg ttgctgggct ttcttggctt gtatcctctc ttgcaatact
    52021 tagatactcc tgcagaaatt cttcctcaat cttatcaata tatttctatg attgtgacct
    52081 gtgtaggtgt cagctttgct tataatcttt ttgcaggctt gttgcggtct attggtgaca
    52141 gtctagcagc cctgggattt ctgattttct ctgccttggt taatgtggtt ctggatctct
    52201 attttattac gcaattgcat ctgggagttc aatccgcagg acttgctacc attatttcgc
    52261 aaggtttatc agcggttctc tgcttttatt atattcgtaa aagtgtgcca gaactcttgc
    52321 cacggtttaa acatttcaaa tgggacaaaa gcttgtacgc ggatctcttg gagcaaggtt
    52381 tggctatggg cttgatgagt tcaattgtat ctatcggcag tgtgatttta cagttttctg
    52441 ttaatacatt tggtgcagtg attattagtg cccagacggc agctcgacgc attatgacct
    52501 ttgcccttct tcctatgacc gctatttctg catcaatgac gacctttgct tctcagaatc
    52561 taggagctaa gcgacctgac cgcattgttc aaggtcttcg aatcggcagt cgtttaagta
    52621 tatcctgggc agtttttgtt tgtattttcc tcttttttgc cagtccagcc ttggtttcct
    52681 tcttggctag ttcgacagat ggttacttga tagaaaatgg aagtctctat ctgcaaatca
    52741 gttcagcctt ttatcccatt ttgagcctct tgttgattta tcgcaattgc ttgcagggct
    52801 tggggcagaa gatccttcct ctagtttcta gctttattga actaatcgga aaaatcgttt
    52861 ttgtggtttt gattattcct tgggcaggat ataagggtgt tatcctttgt gaacctctta
    52921 tctgggttgc catgacagtt caactgtact tctcactatt ccgtcatccc ttgataaaag
    52981 aaggaaaggc aattttggca accaaagtgc aatcctagtt ggatttactg aataaaattc
    53041 atttcctcta gtgaacatcg aaaaaacttg tgttctcttc tttagtttgg tgttgaaaat
    53101 agtttaacag acttttgact tcttttatat gatataataa agtatagtat ttatgaaaag
    53161 gacatataga gactgtaaaa atatactttt gaaaagcttt ttagtctggg gtgttattgt
    53221 agatagaatg cagaccttgt cagtcctatt tacagtgtca aaatagtgcg ttttgaggtt
    53281 ctatctacaa gcctaatcgt gactaagatt gtcttctttg taaggtagaa ataaaggagt
    53341 ttctggttct ggattgtaaa aaatgagttg ttttaattga taaggagtag aatatggaaa
    53401 ttaatgtgag taaattaaga acagatttgc ctcaagtcgg cgtgcaacca tataggcaag
    53461 tacacgcaca ctcaactggg aatccgcatt caaccgtaca gaatgaagcg gactatcact
    53521 ggcggaaaga cccagaatta ggttttttct cgcacattgt tgggaacggt tgcatcatgc
    53581 aggtaggacc tgttgataat ggtgcctggg acgttggggg cggttggaat gctgagacct
    53641 atgcagcggt tgaactgatt gaaagccatt caaccaaaga agagttcatg acggactacc
    53701 gcctttatat cgaactctta cgcaatctag cagatgaagc aggtttgccg aaaacgcttg
    53761 atacagggag tttagctgga attaaaacgc acgagtattg cacgaataac caaccaaaca
    53821 accactcaga ccacgttgac ccttatccat atcttgctaa atggggcatt agccgtgagc
    53881 agtttaagca tgatattgag aacggcttga cgattgaaac aggctggcag aagaatgaca
    53941 ctggctactg gtacgtacat tcagacggct cttatccaaa agacaagttt gagaaaatca
    54001 atggcacttg gtactacttt gacagttcag gctatatgct tgcagaccgc tggaggaagc
    54061 acacagacgg caactggtac tggttcgaca actcaggcga aatggctaca ggctggaaga
    54121 aaatcgctga taagtggtac tatttcaacg aagaaggtgc catgaagaca ggctgggtca
    54181 agtacaagga cacttggtac tacttagacg ctaaagaagg cgccatggta tcaaatgcct
    54241 ttatccagtc agcggacgga acaggctggt actacctcaa accagacgga acactggcag
    54301 acaagccaga attcacagta gagccagatg gcttgattac agtaaaataa taatggaata
    54361 tctttcaaat cagaacagcg catattatta ggtcttgaaa aagcttaata gtatgcgttt
    54421 tcttgtggag atatttcctt caatttttgt tactatatta aacaaaaatc aaaaagcaaa
    54481 ctagaaagtt atgctcaaat aaaatctaaa tttgacaatg taaaccgagt cggatagctt
    54541 taagtactgt tttgaggttg aagatacgat ttttgatagg aactcatcaa ttttagattt
    54601 ttaagcagca tcaataaatt gcttccttgt tttgtcataa tttttttatt taaaaaatta
    54661 tgacaaaagt gtgctattct ttttatgaga ggtgtatgaa tatgataaat gtatgtgata
    54721 aatgtatgtg atgttggaaa aagaataaaa gaacttagaa tatcttcaaa tcttactcaa
    54781 gataagattg ctgaatattt gtctttatat ttgtctttga atcaaagcat gattgccaaa
    54841 atggaaaaag gtgaaaggaa tatcacgaat ggatttaagt aataaagctt caaatcttag
    54901 aaaaaagttg ggagctgatg gtgaagcgcc gatagatatt tttaaattgg tacaaaagat
    54961 agaaaatttg acgctggtat tttatggact cggaaagaat attagcggag tctgttataa
    55021 aggaactcag ttcagtctca ttgcagtcaa ttcagacatg tcattaggaa ggtaaagatt
    55081 ttctttagca catgaactgt atcatcttta ttatgatgag gtgaagaaga gttcagtcag
    55141 tcttatcttg attggtgaag gagatgaaac tgaaagaaaa gcggatcagc ttgcttctta
    55201 ttttttaatt ttcccatctt cactgtatag gatggttgag gaaatcagag aaaatgccaa
    55261 tagaactcat cttgaagtag aagatattat aaaattgggt cagttttatg gtatcagtca
    55321 taaagctatg ttatatagat tgaggaatga tggatacctt gatgcagaag aaattaaaaa
    55381 tatggatatt agtgttatag agacagcttc aagattaggc tatgatacaa gtttatatcg
    55441 tcctttgtca gaaagtaaaa aggaaatggt attaggataa tatattaatt caactgaaca
    55501 acttttagaa aataacagaa tttcgcaagg gaagtatgag gaactgttac tagatgcttt
    55561 cagatatgat attgtatatg ggctagatga agagggggga gttgtcgttt gactagtcgt
    55621 gtatttattg atgcagattg tatttcagta tttttatggg ttggcactga acatctttta
    55681 gaaaagctct attcgggtaa aattgttatt ccacaagagg tgtatgatga aatcaatata
    55741 cctacaattc cccatttaaa atctaggata gatcagttgg tagctaaggg ttcagctgag
    55801 attgtgagca tagacattgg aactgaagaa tacgcattat atagagattt aacaagaaat
    55861 catgataata acaagattat tggtaaggga gaagcggctt ctatttcctt agcgaaaaag
    55921 cataatggga tattaggaag taataaccta agagatgtta aatcatatgt agaagaattt
    55981 tctttagaac atatgacaac aggagatata ctgattgaag cgtttaaagc gtaatttatt
    56041 actgaacaag agggcaatca tatctggaat aatatgctta aaaagagaag gaaaattggt
    56101 gcaaattcat tttcagacta tcttcgtgga agtattcatc aaaatagaca aaaataaatt
    56161 tggataaatc gaactcacta ttcaggaggc atatgagcaa ttcgaaaaag aaaaatgtca
    56221 aattgagcct ataggagtag aagtgaaata gtaagtcctg catagtggat gagagaaaag
    56281 ttctccttga agttttcctg aactatcagt cgcatgtcaa acgatatgta gggtaatgtg
    56341 agaggggata gcgagtagtt tttggttatt ttatcaaaaa acttatattt tattatactg
    56401 aatgataaaa tataataaaa atgatagaat aaggaaaaaa catgaatgtc aaaaagataa
    56461 tgtcaatttt tcaatccttt tatgttgatg tcagtattga ggaactgact ttgactttac
    56521 caatcagttt tgtaaaaagg tttgagtata ctcaaatgac ttttcataag gaatcatttt
    56581 tattgattaa agaaaagaga agggggagtt tgagttcatt tgttactcag gctcgcacta
    56641 tgggtgaaaa agccaatatg gatgttgttt tgctgttttc gaagttatca gacagtgaaa
    56701 aaaagcaatt acttcaagct agagttccgt ttgtagactt taagggaaac ctcttcttcc
    56761 ctccattggg actagtactg aatgcgaatg atactgaagt ccctaaggaa ttaacaccta
    56821 gcgaacaatt aacgtggatt gcctttttat tgacaaaagg tcaaaaagta gtagatgttg
    56881 atttgctttc acaagtcact ggacttccaa actcaacaat ttataggtgt ttgaggactt
    56941 ttaaagcttt atattggtta aacaagcaaa ataagcttta cacatatacg gtgtcaaaga
    57001 aagaattatt cttaaaatcc gtgtcatgtt tatttaatcc catcaaaaaa cggattttat
    57061 tgccagatgg cgatataaag cagataaaat ctgtttctaa tcttctatat ggtggtgctt
    57121 atgctttgtc gcattcaact tttttagctg aaacggatga aaatattagc tatgtcatat
    57181 ggcagagaaa attcaatcag ttatccttgc cattttctca gcatatttta aaaggaaaga
    57241 tgctagagat atggaaatat cgtccttttg tatctgagtt ttggaatgat tttaaaaata
    57301 atcatgataa acaatttgta gatccgattt ctctttattt gaccttaaaa gatgatgatg
    57361 acccacgtat agaggaagag agtgaagcac tagaaaatat gatattacag tatctgggag
    57421 aagatgatgc cagctaatac gaaagttatt tttcaagaaa cgtttgcgga ttttcagaac
    57481 tattatgttc tgattggggg aactgctacc tctatcgtat tggattcgca aggatttaaa
    57541 agtcgcacaa caaaagatta tgatatggtc atcattgatg aagtaaaaaa taaggaattt
    57601 tatactacct tgaatcattt tttagaattg ggagagtatc aaggaagtca gaaagatgag
    57661 aaagcgcagc tttttcgatt tacaacaact aatcctgagt ttccttctat gattgaacta
    57721 tttagtatct taccagaata tccattaaag aaggacggtc gagaaattcc cttacatttt
    57781 gaccaagatg ctagtttatc agccttatta ttgaatgaag attattataa tatattggtg
    57841 catgaaaaag aaaccattca ggggtatttg gtattgagta attgtggtc
//
LOCUS       DAVKXA010000007        53621 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKXA010000007 DAVKXA010000000
VERSION     DAVKXA010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.007"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(73..882)
                     /locus_tag="VW883_000459"
     CDS             complement(73..882)
                     /locus_tag="VW883_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0273651.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGIGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(884..1687)
                     /locus_tag="VW883_000460"
     CDS             complement(884..1687)
                     /locus_tag="VW883_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0273652.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VW883_000461"
     CDS             complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VW883_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0273653.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3520..4227
                     /locus_tag="VW883_000462"
     CDS             3520..4227
                     /locus_tag="VW883_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0273654.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4232..5254
                     /locus_tag="VW883_000463"
     CDS             4232..5254
                     /locus_tag="VW883_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0273655.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5271..6140
                     /gene="licA"
                     /locus_tag="VW883_000464"
     CDS             5271..6140
                     /gene="licA"
                     /locus_tag="VW883_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0273656.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            6130..7008
                     /locus_tag="VW883_000465"
     CDS             6130..7008
                     /locus_tag="VW883_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0273657.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7020..7709
                     /locus_tag="VW883_000466"
     CDS             7020..7709
                     /locus_tag="VW883_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0273658.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7795..8643
                     /gene="dprA"
                     /locus_tag="VW883_000467"
     CDS             7795..8643
                     /gene="dprA"
                     /locus_tag="VW883_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0273659.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9526..10569
                     /locus_tag="VW883_000468"
     CDS             9526..10569
                     /locus_tag="VW883_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0273660.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10736..12823
                     /gene="topA"
                     /locus_tag="VW883_000469"
     CDS             10736..12823
                     /gene="topA"
                     /locus_tag="VW883_000469"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0273661.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13044..13403
                     /locus_tag="VW883_000470"
     CDS             13044..13403
                     /locus_tag="VW883_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0273662.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13496..14128
                     /locus_tag="VW883_000471"
     CDS             13496..14128
                     /locus_tag="VW883_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0273663.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14172..14828
                     /locus_tag="VW883_000472"
     CDS             14172..14828
                     /locus_tag="VW883_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0273664.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14847..15881
                     /locus_tag="VW883_000473"
     CDS             14847..15881
                     /locus_tag="VW883_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0273665.1"
                     /translation="MNFQLAKYSLLKKFSENIEFTTPGEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIHQDGVLKNPLTYEIITPELVGVKIPLGKLSGRHAF
                     VEKLRELALDFTEEDIKPLFAKFKALADKKQEITDADTRALVAGTMVENPEGFHFDDL
                     QLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIFNAIDKFFNQSVRLVSYTIDA
                     VTDGIDAQDRVLVTVENRDIETIFNAAGLDFDVLKASAIAYINANTFVQKENAGEMGC
                     SVSYHDMPSV"
     gene            15893..16930
                     /gene="leuB"
                     /locus_tag="VW883_000474"
     CDS             15893..16930
                     /gene="leuB"
                     /locus_tag="VW883_000474"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0273666.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDTERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            16927..17196
                     /locus_tag="VW883_000475"
     CDS             16927..17196
                     /locus_tag="VW883_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0273667.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17200..17559
                     /locus_tag="VW883_000476"
     CDS             17200..17559
                     /locus_tag="VW883_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0273668.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17721..18345
                     /locus_tag="VW883_000477"
                     /pseudo
     CDS             17721..18345
                     /locus_tag="VW883_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007122522.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            18508..20191
                     /locus_tag="VW883_000478"
                     /pseudo
     CDS             18508..20191
                     /locus_tag="VW883_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042409.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            20366..21352
                     /locus_tag="VW883_000479"
     CDS             20366..21352
                     /locus_tag="VW883_000479"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0273669.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEVGRISFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            21416..21487
                     /locus_tag="VW883_000480"
     tRNA            21416..21487
                     /locus_tag="VW883_000480"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21449..21451,aa:Arg,seq:ccg)
     gene            21670..22368
                     /locus_tag="VW883_000481"
     CDS             21670..22368
                     /locus_tag="VW883_000481"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0273670.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            22359..25898
                     /gene="smc"
                     /locus_tag="VW883_000482"
     CDS             22359..25898
                     /gene="smc"
                     /locus_tag="VW883_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0273671.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSHQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            25895..26689
                     /locus_tag="VW883_000483"
     CDS             25895..26689
                     /locus_tag="VW883_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0273672.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            26689..27507
                     /locus_tag="VW883_000484"
     CDS             26689..27507
                     /locus_tag="VW883_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0273673.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            27511..28788
                     /gene="ftsY"
                     /locus_tag="VW883_000485"
     CDS             27511..28788
                     /gene="ftsY"
                     /locus_tag="VW883_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0273674.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(28834..30321)
                     /locus_tag="VW883_000486"
     CDS             complement(28834..30321)
                     /locus_tag="VW883_000486"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0273675.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWD
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(30470..31210)
                     /locus_tag="VW883_000487"
     CDS             complement(30470..31210)
                     /locus_tag="VW883_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0273676.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(31210..33375)
                     /locus_tag="VW883_000488"
     CDS             complement(31210..33375)
                     /locus_tag="VW883_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0273677.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSNNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            33544..34497
                     /locus_tag="VW883_000489"
     CDS             33544..34497
                     /locus_tag="VW883_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0273678.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            34574..36562
                     /gene="uvrB"
                     /locus_tag="VW883_000490"
     CDS             34574..36562
                     /gene="uvrB"
                     /locus_tag="VW883_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0273679.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEAVTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            36572..37135
                     /locus_tag="VW883_000491"
     CDS             36572..37135
                     /locus_tag="VW883_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273680.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            37101..37589
                     /locus_tag="VW883_000492"
     CDS             37101..37589
                     /locus_tag="VW883_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273681.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            37663..38130
                     /locus_tag="VW883_000493"
     CDS             37663..38130
                     /locus_tag="VW883_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0273682.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(38127..38642)
                     /locus_tag="VW883_000494"
     CDS             complement(38127..38642)
                     /locus_tag="VW883_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0273683.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(38654..39181)
                     /locus_tag="VW883_000495"
     CDS             complement(38654..39181)
                     /locus_tag="VW883_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0273684.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(39459..40022)
                     /locus_tag="VW883_000496"
     CDS             complement(39459..40022)
                     /locus_tag="VW883_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0273685.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(40006..40557)
                     /gene="coaC"
                     /locus_tag="VW883_000497"
     CDS             complement(40006..40557)
                     /gene="coaC"
                     /locus_tag="VW883_000497"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0273686.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(40569..41258)
                     /gene="coaB"
                     /locus_tag="VW883_000498"
     CDS             complement(40569..41258)
                     /gene="coaB"
                     /locus_tag="VW883_000498"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0273687.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            41488..43158
                     /locus_tag="VW883_000499"
     CDS             41488..43158
                     /locus_tag="VW883_000499"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0273688.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWERVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            43486..44661
                     /gene="mutY"
                     /locus_tag="VW883_000500"
     CDS             43486..44661
                     /gene="mutY"
                     /locus_tag="VW883_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0273689.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            44716..45420
                     /locus_tag="VW883_000501"
     CDS             44716..45420
                     /locus_tag="VW883_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0273690.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            45413..46762
                     /gene="vicK"
                     /locus_tag="VW883_000502"
     CDS             45413..46762
                     /gene="vicK"
                     /locus_tag="VW883_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0273691.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            46764..47573
                     /locus_tag="VW883_000503"
     CDS             46764..47573
                     /locus_tag="VW883_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0273692.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            47664..47906
                     /locus_tag="VW883_000504"
     CDS             47664..47906
                     /locus_tag="VW883_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0273693.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            47908..48162
                     /locus_tag="VW883_000505"
     CDS             47908..48162
                     /locus_tag="VW883_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0273694.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            48209..48904
                     /locus_tag="VW883_000506"
     CDS             48209..48904
                     /locus_tag="VW883_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV0273695.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(49253..50239)
                     /locus_tag="VW883_000507"
     CDS             complement(49253..50239)
                     /locus_tag="VW883_000507"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0273696.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            50433..52901
                     /gene="gyrA"
                     /locus_tag="VW883_000508"
     CDS             50433..52901
                     /gene="gyrA"
                     /locus_tag="VW883_000508"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0273697.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            52901..>53621
                     /gene="srtA"
                     /locus_tag="VW883_000509"
     CDS             52901..>53621
                     /gene="srtA"
                     /locus_tag="VW883_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0273698.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFN"
BASE COUNT        16587 a         9360 c        11768 g        15906 t
ORIGIN      
        1 tgtatttcat tttctactaa aattatgttt ttgaataacc tctatcttag tagtttgtat
       61 aatccccctc aatcagtttt tgcgataagc tttaatgcta tgactatacc actcttgcat
      121 ttcttttgat ggtggtgtca tataatcgcc atacatctgg gttaaaaatt ggtcatattt
      181 tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa atcagttctt taaaggtatc
      241 aactgggaag atttctttca tcccttcctt accgatccca attcctcctt catattgagg
      301 agtgttggtt acagcatttt tgactagttg atcaattttc ttgtaaaagt agcgaggatt
      361 gacaaatcgg agagcgtacc agctacataa tctaagaaaa tcttttagtt tgctatcacc
      421 gtgaactgct cgtgattttt tgatataagc tagttgacga agagccacat acttatagct
      481 cttgtcgaca atactcaagt ctgtaaatcg atcaattggg aagacatcga tgaaaaggct
      541 ggtatcatga cgcttgtact taacatggtc ttctataaca gtagaagtgt ccaaaatcga
      601 tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa agaaccttgt agcgagggtg
      661 attttcttct tcaataatct tcagtaaacg ctcataatcc tcacgataaa gggaaatatc
      721 aatatcatca tcccaaggaa tcataccttt gtggcggatg gctccaagca tggttccata
      781 actgagaaaa taaggaatat catgtttctt acaagtctca tcaatatagt ccagcagggc
      841 tagttgaatt tctttaattt cttttttttc taaatattgc atcctaatcc tccaatttat
      901 aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg tggtagggtc atataatctc
      961 cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc aggaaggctt aaattctcaa
     1021 agggtaaatc gattgtttta tcaaaggtac cacttgggaa gacttccttt tccttaaatt
     1081 ttgaagggat aaaagccata tattgcccat tttcacgact atatttttga atttctttct
     1141 cgattttatt tgcaaaataa cgaggagaaa ccggtcgaag gagtaaccag aaggctgttc
     1201 gtatccaatc ttttaaaagg ctatccttat agacaatatt tttatgttta ctgaaagaca
     1261 gcagtttgaa gctttccagt ttataacaag tatcaatgac cttaggatca tcaaagcgat
     1321 ctatagggaa aatatcgata aagataccag actcataggt ttttgtattt cgagtatcaa
     1381 taattttagt cgtactgtcg gttatcttga taaagttgtt aaagtagttc ttatcagttt
     1441 ctaaggatag gagcttatac ttgctttttt ccttttgaaa aatgttaata aatcgttggt
     1501 agtcttctct aggcatggat aaatcaatat cgtcgtccca agggataaag ccctcatgtc
     1561 gaaccgcccc aatcagagtg ccgtagttaa taatatagtt gatattgtgc tttttacaga
     1621 gagtatcaat ataattcaaa atttctaatt caatttgttt ggcatcttca acggttagtt
     1681 gtttcatttt aaactcctaa gattttttaa atttattttt taaggctagg acatggttta
     1741 aaaattcata gaaaatgcta tcttttgtga agacaagtag actaatataa gagatagctg
     1801 atagcaagac aatcaaacca gtattaatca aaaatggcaa attaatgacc atatccacag
     1861 gatacacgaa attaatcagg aaataaattg ctacaaagga aagtgaaaag agagagtatc
     1921 gaacagtata gctaaagata tgtcccaagt ggatgagttg ttttctatgg atgaaaatga
     1981 tatagaaaac aagtagagaa gcctctgata acatagttgt cagtaagtag tattcgggag
     2041 ccacgatatg gttgaaaaag aggagactat tcaagcccaa attgagtagc ccagcaaaga
     2101 ctgtatagac tgtgatacgt ttttcatagc cattggtaaa gagaatttgg gaaccaagaa
     2161 tggtatctaa ggccagaata atcgtacgaa aagcgaagag agaggtcaag atgccgcctc
     2221 cgatatattt ttcactaccg taaagtagga tggcatttgg tcctaaaacc atgagtccaa
     2281 aactcagtgg aatgataaag aagttaaaga ttcgactacc tctattaacc agagaaacat
     2341 aggcttcttt gtctcctttc cccagatagt aactgagacg aggcacactc actccaattg
     2401 cacctgttac aaccccagct ataacggtca caattcgctg agctatggta tagtaactaa
     2461 cgttgacatc aatccctgtt ttaacgagga agaggcgatc taaaaaagtg aagagcatat
     2521 tggcattggc aaagactaac atggctgtca gagggagaaa gagtggttta aaatcactta
     2581 ggtgaatctt aacaagtttg atgtctcttt taatccaaaa ataactaatc aggtagttaa
     2641 tcagcgtcga taaactcatc acaagtgtat agacaacaat atcgtgttca tttttaacaa
     2701 ataagaaaat agagaccagc atcaggatac ggatgaaggc agttttgtaa aagagaaaac
     2761 tgtaattttc cagagcttca ttgacccatt cgattgaaaa aatctgggca atgagttgaa
     2821 tccccataac aaggtagacc tttttgacga ttggattatc agtaaagaag agaggatagg
     2881 ctaggatata gacagcagtg gtcaaaatcg tacaagcgat gcacaaataa aaaagactag
     2941 aaaaggttct gttaagatct tttttgttat ccttgacatt actgatagcc cttaaaccgt
     3001 agttatagac accataagtt gcaaagggca agaaaaatga caaaatagtg tcgactgagt
     3061 tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac ataggttcca gttaggatgg
     3121 gaaaaataat attcaagaca cgaattccca tgtaagatag agcatttaat tttatacttt
     3181 tcattcaatt tacctcgttt ttcattatat cataaagtta gctaataaga aatgaagggc
     3241 agtaagtcaa gtaatcactt tgaagtttca aatcttaagt tttaagtttt ctttaaggaa
     3301 agtatattat tctgaaggac tctaaaattt cgcagccatt tattagtaat tgctacagaa
     3361 ttcctagtca ttactagaaa tggactagtt tcttggaata atagaactgc ataattctcc
     3421 tattctagaa ggggaggacc agtatttctt ttatgatagg actagattgt ggtataatag
     3481 agagaataag tttttttagt aagacaaagg agaaaataga tgatttatgc aggaattctt
     3541 gccggtggaa ctggcacacg catggggatc agtaacttgc caaaacaatt tttagagcta
     3601 ggtgatcgac ctattttgat tcatacaatt gaaaaatttg tcttggagcc aagtattgaa
     3661 aaaattgtag ttggtgttca tggagactgg gtttctcatg cagaagatct tgtagataaa
     3721 tatcttcctc tttataagga acgtatcatc attacaaagg gtggtgctga ccgcaataca
     3781 agtattaaga acatcattga agccattgat gcttatcgtc cgcttactcc agaggatatc
     3841 gttgttaccc acgattctgt tcgtccattt attacacttc gcatgattca ggacaatatc
     3901 caacttgccc aaaatcatga cgcagtggac acagtggtag aagcggttga tactatcgtt
     3961 gaaagtacca atggtcaatt tattacagat attccaaatc gtgctcacct ttatcaagga
     4021 caaacacctc aaacattccg ttgcaaggac ttcatggacc tttatggatc tctttctgat
     4081 gaagagaagg aaatcttgac agatgcatgt aaaatctttg tgatcaaagg aaaagatgtg
     4141 gctttggcca aaggtgaata ctcaaatctg aagattacaa ccgtaacaga tttgaagatt
     4201 gcaaaaagta tgattgagaa agactagtaa aatgattaat caaatttatc aactaactaa
     4261 gcctaagttt atcaatgtca aatatcagga agaggctatt gaccaagaga atcatatcct
     4321 tatccgtccc aactacatgg ctgtctgtca tgcggatcag cgttactatc agggaaaacg
     4381 tgatcccaag attttgaata aaaagcttcc aatggcaatg attcacgagt catgtggaac
     4441 cgtcatttct gacccgaccg gaacctacga ggttggtcaa aaagttgtca tgattcccaa
     4501 tcagtctcct atgcagagtg atgaagaatt ctatgaaaac tacatgacag ggacccattt
     4561 cttgtctagt ggatttgatg gctttatgag agagtttgtt tctctcccta aagatcgtgt
     4621 ggtggcttat gatgctattg aagatacggt tgcagccatt acagagtttg tcagtgtggg
     4681 catgcacgct atgaatcgtc tattgactct tgctcatagc aagcgggagc ggatcgccgt
     4741 tattggagat ggaagtttag cttttgtggt tgccaatatt atcaactata ctttgccaga
     4801 agcagagatt gtggttattg gtcgtcattg ggaaaagttg gaactcttct catttgccaa
     4861 agaatgctat attacggata atattcctga agatttggcc tttgaccatg cttttgaatg
     4921 ttgtggtggt gatggtactg gaccagctat taatgacttg attcgctaca ttcgtcctca
     4981 gggaacgatt ctcatgatgg gagttagcga atataaagtc aatctcaata ctcgcgatgc
     5041 cttagaaaag ggcttgattt tggttgggtc atctcgttct ggtcgcattg attttgaaaa
     5101 tgctatccaa atgatggaag tcaagaaatt tgccaatcgt cttaaaaata tcctttatct
     5161 agaagaacct gtaagagaaa ttaaagatat tcatcgtgtc tttgcaaccg atttaaacac
     5221 agcctttaaa acagtgttta agtgggaagt ataagtactg gaggttaatt gtggagaaaa
     5281 tcattaaaga aaaaatttct tccttactta gtcaagaaga ggaagtcctc agtgttgaac
     5341 aactgggtgg aatgaccaat caaaactatt tggccaaaac aacaaataag caatacattg
     5401 ttaaattctt tggtaaaggg acagaaaagc ttatcaatcg acaagatgaa aagtacaatc
     5461 ttgaactact aaaggattta ggcttagatg taaaaaacta tctttttgat attgaagctg
     5521 gtatcaaagt aaatgagtat atcgaatctg cgattacgct tgattcaacg tcaatcaaga
     5581 ccaagttcga caaaattact ccaatattac aaactattca tacgtctgct aaggaattaa
     5641 gaggagaatt tgctcctttt gaagaaatca aaaaatacga atccttgatt gaagaacaaa
     5701 ttccttatgc caactatgaa tctgttagaa atgcagtctt ctccttagag aaaagactgg
     5761 ctgacttagg tgttgacaga aaatcttgtc atatcgattt ggtgcctgaa aactttatcg
     5821 aatcacctca aggacgactt tatttgattg actgggaata ttcatcaatg aatgatccaa
     5881 tgtgggattt ggctgccctc tttttagagt ctgaattcac ttcccaagag gaagaaactt
     5941 tcttatctca ctatgagagt gaccaaacac cggtttctca tgaaaagatt gctatttata
     6001 aaattttaca agatactatt tggagtctat ggactgtcta taaggaagag caaggtgaag
     6061 attttggtga ctatggtgtg aatcgttacc aaagagctat taaaggtttg gcttcttatg
     6121 gaggttcaga tgaaaagtaa aaacggagtt ccttttggcc ttctctcagg tattttctgg
     6181 ggcttgggtc taacggttag tgcttatatc ttttcgattt ttacagattt gtcacccttt
     6241 gtggtggctg caactcatga ttttttgagc atctttatct tactagcttt tctcttggta
     6301 aaagaaggga aagttcgcct ctcaattttc ttaaatattc gcaatgtcag tgttatcata
     6361 ggagccttgc tagcaggccc tatcggtatg caggccaatc tttatgcagt taagtatatc
     6421 ggaagttctt tagcttcatc tgtatcggct atttaccctg cgatttcagt tctattggct
     6481 ttcttctttt tgaagcacaa gatttcgaaa aatactgtat ttgggattgt cttgattatt
     6541 ggagggatta ttgcccagac ctataaggtt gaacaggtta attctttcta cattgggatt
     6601 ctttgtgctt tggtttgtgc tattgcatgg ggaagtgaga gtgttcttag ctcttttgcc
     6661 atggaaagcg aattgagtga aatcgaagcc ctcttaatcc gtcaagtaac ttcgttcttg
     6721 tcctatcttg tgattgtgct cttctctcat cagtcatttg ttgcagtagc caatggacaa
     6781 ttgctaggtc tcatgattgt ctttgtagcc tttgatatga tttcctattt ggcttattat
     6841 atcgctatca atcgcttgca accagccaag gctacaggct tgaacgtgag ctatgtagta
     6901 tggactgtct tgttcgcagc tcttttcttg ggaacatcat tagatatgct gaccattatg
     6961 acgtcacttg tcgtcattgc tggagtttat attattatta aagaataaag gagattcgtg
     7021 tgaaagccat tatcttagca gcgggattgg gaactcgctt gcgtcctatg actgaaaata
     7081 cccctaaagc cttggttcag gttaatcaaa aacctttgat tgaataccaa attgagtttc
     7141 tcaaagaaaa aggaatcaat gacatcatca tcatcgttgg ttatcttaaa gaacaattcg
     7201 attatttaaa agaaaaatac ggtgttcgcc tcgttttcaa tgataaatac gctgactaca
     7261 ataactttta ctctctctat cttgtaaaag aagaattggc caacagctat gttattgatg
     7321 ctgacaatta tctctttaaa aatatgttcc gcaatgattt gacacgttcg acttatttta
     7381 gtgtttatcg tgaagattgt accaacgaat ggttcttggt ctatggagat gactacaagg
     7441 ttcaagacat tattgttgat agcaaggcag gtcgcatcct tagtggtgta tccttctggg
     7501 atgctccaac tgcagaaaag attgtcagct ttatcgacaa ggcttatgca agtggtgaat
     7561 ttgttgatct ctactgggac aatatggtta aggataatat caaagagcta gatgtctatg
     7621 ttgaagaatt agaaggcaat agcatttatg agatcgatag tgtccaagac tatcgtaaat
     7681 tagaagaaat tcttaaaaac gaaaattaaa gattccaaca tctgacaaaa tagtcggatg
     7741 ttttttgatt ttttacgaat agatagatga gtagaaaaag aaatggagtt atttatgaaa
     7801 atcacaaact atgaaatcta taagttaaaa aaatcaggtt tgaccaatca acagattttg
     7861 aaagtgctag aatacggtga aaatgttgat caggagcttt tgttgggtga tattgcagat
     7921 atctcaggtt gccgtaatcc agccgttttt atggaacgtt attttcagat agacgatgcg
     7981 catttgtcga aagagtttca aaaatttcca tctttctcta ttttagatga ctgttatcct
     8041 tgggatttga gtgaaatata tgatgcgcct gtacttttat tttacaaggg aaatcttgac
     8101 ctcctgaaat tcccgaaggt agcggtcgtg ggcagtcgtg cttgtagcaa acagggagct
     8161 aagtcagttg aaaaagtcat tcaaggcttg gaaaatgaac tggttattgt cagtggtctg
     8221 gccaagggca ttgacacagc agctcatatg gcagctcttc agaatggcgg aaaaaccatt
     8281 gcagtgattg gaacaggact ggatgtgttt tatcctaaag ccaacaaacg cttgcaagac
     8341 tacatcggca atgaccatct ggctctaagt gaatatggac ctggcgaaca acctctgaaa
     8401 tttcattttc ctgcccgtaa tcgcatcatt gctggacttt gtcgtggtgt gattgtagca
     8461 gaggctaaga tgcgttcagg tagtctcatt acctgtgagc gagcaatgga agaaggacgc
     8521 gatgtctttg ctattcctgg tagcatttta gatggactat cagacggttg ccatcatttg
     8581 attcaagaag gagcaaaatt ggtcaccagt gggcaagatg ttcttgcgga atttgaattt
     8641 taaaaatgac ctaagctaga attctaagaa aaaatcaatt ttaagagaaa atgaacccaa
     8701 catttccata ataaaacgca tattagcaag tttttaacac ttgataatat gcgttttttc
     8761 taagtggatt agtagagtag aggatttttt catataatac tcttcgaaaa tctcttcaaa
     8821 ctacgtcagc ttccatctgc aacctcaaaa cagtattttg agctgacttc gtcagtctta
     8881 tctacaacct caaagcagtg ctttgagcaa cctgtggcta gcttcctagt ttgcgctttg
     8941 attttcattg agtataaggg aaagtatagt gaattgaaat aagatgtgaa caactctatc
     9001 aggaaagtca aattaattta tagaaatatt ttagcagcca aggtgcactg ttatagattc
     9061 aatacactat aatttagtgt aattgagaaa ggagaaatga ttgtgattga tgttggctag
     9121 gttatgttca atgattccta ccgtctcaaa tcttgtcagt aaggaaaaat aaattcttca
     9181 aaagtagaga ttacaaggct tgtttaagaa agaattcaaa gaccttgaca aataaaaata
     9241 aaatggttat tataagaaat ggtctaaaat agatgatgat acttttcgaa aatcttttta
     9301 cgtcagctca gctttgcctt gctgtgtttt gagcaagcta cggttagctt ccgagtttga
     9361 ttttcattta ctagaaatga aactgatgag agatatcagt agacatttga gtcaggatat
     9421 tatggaaaat gataaaaaga gctcgtgaga ttggcatatc agactactaa agtattgagt
     9481 ttgttaggat tttagcgact agttagctgg gaaaggaaga tatttgtgac aaataataaa
     9541 ctgtattcgt tgatagaatt tagaaataaa atatatgaag aattagaact ttccagaagt
     9601 gatttagcga ttttactatg tgccatgctt atcgcctcta tcggattaaa tatggattcg
     9661 actcccgtga ttattggagc catgttaatc tctcctttga tgacacctat tctgggagtg
     9721 gggctctctc tagctatatt tgattttaaa ttgttaagaa aatcttttaa aatattagct
     9781 attcaaattc ttgccagtct aatagcttca acactttatt tttatctttc tcccatttcg
     9841 tatgctagtt cggagattgt tgctagaacc tctccgacta tttgggatgt tctcattgct
     9901 tttgtaggag ggatagcagg tattattggt gctaggaaaa aagagaccaa taatattgtt
     9961 cctggtgttg ctattgcaac cgccttgatg cctcctcttt gtacagtagg ttatgctatt
    10021 gcttctgcta atctaaaatt tatcataggc tcctcttacc tattcctcat caattgtagc
    10081 tttattgtca ttgcgactta tataggtgtt aggttgatga tggttaagaa acattatttt
    10141 aaagataatg aagaagactc taaaatgcgt aggattttgc ttctagttgc tgttttgctg
    10201 atgattccga gtttcatctc tgcaacgact ttagtgagag aaacgttgaa aaaagagtcc
    10261 cttaagaaat ttatatcaga gcagtttcag gggtataata ttttgaaaaa aacctattct
    10321 aaaaagactc ataccctaaa gctaaccatt tcaggaaatt atttgacaga agaagaactc
    10381 gatatgattt caagtaagag aggtgactat ggtttaagtg atgtttctgt tcaagtttca
    10441 caattgtctg attcagaaca acttagtaag gaagagctgg tggagtattt cttccagtat
    10501 atcaaggata aggaagcaaa agaaaaggag aaagccaata aatttgatac agagtctgag
    10561 gagcaataat ttcttgagaa tagctggttt ctctcgtgag tcttctatgt atatcaaagg
    10621 aagactgagg ttttaagtat aaaacttttc ttctattata gtagctaagt cttgacaggg
    10681 ttcaaaaaat ggtttacact ttataaagtt tattactttg aaaaggtgtg atactgtggc
    10741 tacggcaaca aaaaagaaaa aatcaacagt taaaaaaaat ctagtcatcg tggagtcgcc
    10801 tgctaaggcc aagacgattg aaaaatatct aggcagaaac tacaaggttt tagccagtgt
    10861 cgggcatatc cgtgatttga agaaatccag tatgtccgtc gatattgaaa ataattatga
    10921 accgcaatat atcaatatcc gaggaaaagg ccctcttatc aatgacttga aaaaagaagc
    10981 taaaaaagct aataaagttt ttctcgcgag tgacccggac cgtgaaggag aagcgatttc
    11041 ttggcatttg gcccatattc tcaacttgga tgaaaatgat gccaaccgtg tggtcttcaa
    11101 tgaaatcacc aaggatgcag tcaaaaatgc ttttaaagaa cctcgtaaga tcgatatgga
    11161 cttggtcgat gcccaacaag ctcgtcggat cttggatcgc ttggtagggt attcgatttc
    11221 gcctattttg tggaagaagg tcaagaaggg cttgtcagca ggtcgcgttc agtccattgc
    11281 ccttaaactc atcattgacc gtgaaaatga aatcaatgcc ttccagccag aagaatactg
    11341 gacagttgat gctgtcttta aaaagggaac caaacaattt catgcttcct tctatggagt
    11401 agatggtaaa aagatgaaac tgaccagcaa tgacgaagtc aaggaagtct tgtctcgtct
    11461 gactagtaaa gacttttcag tagatcaggt ggataagaaa gagcgcaagc gcaatgctcc
    11521 tttaccctat accacttcat ctatgcagat ggatgctgcc aataaaatca atttccgtac
    11581 tcgaaaaacc atgatggttg cccaacagct ctatgaagga attaatattg gttctggtgt
    11641 tcaaggtttg attacctata tgcgtaccga ttcgactcgt atcagtcctg tagcgcaaaa
    11701 tgaggcggca agcttcatta cggatcgttt tggtagcaag tattctaagc acggtagcaa
    11761 ggtcaaaaac gcatcaggtg ctcaggatgc ccatgaggct attcgtccgt caagtgtctt
    11821 taatacacca gaaagcatcg ctaagtatct ggacaaggat cagctcaagc tatataccct
    11881 tatctggaat cgttttgtgg ctagccagat gacagcggcc gtttttgata ccatggctgt
    11941 taaattgtct caaaatggag ttcaatttgc tgccaatggt agtcaggtta agtttgatgg
    12001 ttatcttgcc atttataatg attctgacaa gaataagatg ttaccggaca tggttgttgg
    12061 agatgtggtc aaacaggtca atagcaaacc agagcaacat ttcacccaac cgcctgcccg
    12121 ttattctgaa gcaacactga ttaaaacctt agaggaaaat ggggttggac gtccatcaac
    12181 ctatgcgcca accattgaaa ccattcagaa acgttattat gttcgcctgg cagccaaacg
    12241 ttttgaaccg acagagttgg gagaaattgt caataagctc atcgttgaat atttcccaga
    12301 tatcgtaaac gtgaccttca cagctgaaat ggaaggtaaa ctggatgatg tcgaagttgg
    12361 aaaagagcag tggcgacggg tcattgatgc tttttacaaa ccattctcta aagaagttgc
    12421 caaggctgaa gaagaaatgg aaaaaatcca gattaaggat gaaccagctg gatttgactg
    12481 tgaagtgtgt ggcagtccaa tggtcattaa acttggtcgt tttggtaaat tctacgcttg
    12541 tagcaatttc ccagattgcc gtcataccca agcaatagtg aaagagattg gtgttgagtg
    12601 tccaagctgt catcagggac aaattattga gcgaaaaacc aagcgtaatc gcctattcta
    12661 tggttgcaat cgctatccag aatgtgaatt tacctcttgg gacaagcctg ttggtcgtga
    12721 ctgtccaaaa tgtggcaact tcctcatgga gaaaaaagtc cgtggtggtg gcaagcaggt
    12781 tgtttgtagc aaaggcgact acgaggaaga aaagattaaa taagaggagg ggcccgaaag
    12841 taaatttcag gctccttttg gttagaactt gacaaaatac atcattttat gcgaaactag
    12901 aagaagatta ttttatactc aatgagaatc aaagagcaaa ttagaaagct agtcgcaggt
    12961 tgctcaaagc actactttga ggttgaagat ggaagctgac ctggtttgaa gagattttcg
    13021 aagagtatta actaggagaa gttatgcgtc ttatctatct gataattggt tttttatcac
    13081 tggccttggc tattgttggg gttgttttac ccttgttgcc gacaacgcct ttccttttgt
    13141 tgtctattgc ttgtttctcc agaagttcca agcgtttcga agactggctt tatcatacca
    13201 agctctatca aacatatgta gctgattttc gcgagactaa gtctattacg cgtgaacgaa
    13261 agaaaaaaat catcgtctct atctacgtct tgatgggaat ttctatttat tttgcacctc
    13321 ttttaccagt caaaatcggt ctgggtgctt tgaccatctt tattacttat tatctcttca
    13381 aggtcattcc agacaaagaa tagttaaaac agtagttatt tgccttgata aaattgaaag
    13441 catattcata acaatatgat ataataaatt tgaagtaata ttcaaggaga atcaaatgat
    13501 ttacgaattt tgtgctgaaa atgtgacttt acttgaaaaa gcgatgcagg ctggagctcg
    13561 tcggattgaa ctctgtgata atctagcagt tggtgggaca acacccagct atggagtgac
    13621 taaggcagcg gttgaactgg cagctaacta cgatacaacc atcatgacca tgattcggcc
    13681 acgtggtggt gactttgtct ataatgactt agaaattgct atcatgctag aagacattcg
    13741 tttgactgct caggctggaa gtcaaggggt tgtatttgga gctttaactg ctgataaaaa
    13801 gttggataag cctaatctgg aaaagttaat tgctgcatca aaaggaatgg aaattgtctt
    13861 tcacatggcc tttgatgaac taagtgatga agatcaaccg gaagctattg actggctcag
    13921 tcaagccggt gtcactcgta tcctaactcg tgctggtgtg tctggcgact ccttagaaaa
    13981 acgttttgtt cactatcaca gaattttgga gtacgctaaa ggtaaaattg aaattctacc
    14041 aggtgggggg attgaccttg aaaaccgtca aacctttatc gaccaggtgg gggtaacaca
    14101 attgcatggt actaaggttg ttttttaaaa aatagaaagg aactgctagc tttgggtagc
    14161 agttttcact tatgtttgaa atttttaaat cctatcaatt taatcaagaa aaggctcatg
    14221 attatggttt tatagaaaat agcgaagtct ggacatatag ttgccagatt ttgcaaggtg
    14281 actttgtcat gactgtgtcc atcactgctg ataatgtgaa ctttcaagtc tttgaccaag
    14341 aaactggtga cctctatcct cacgttcata tggaaagcat gaggggaagt tttgtcggaa
    14401 atgtccgtga ggcttgtctg gagattcttt accagattcg gaaggcttgt tttgatgtgc
    14461 aagattttat ctgtcatcag actaagcgta tcatgactca agttcaggaa aagtatggaa
    14521 accagttgga gtatctgtgg gaaaaatcgc ctgatacagc tgtattgcgc catgaaggca
    14581 atcaaaagtg gtatgccgtc ttgatgaaaa tctcttggaa taagctggaa aagggaagag
    14641 aaggacaagt ggaagcagtc aacctcaagc atgaccaagt agctaattta ctttcacaaa
    14701 aggggattta tccagccttt catatgagca agcgctactg gattagtgtg tcccttgatg
    14761 atactttatc agatgaagaa gtactggaat tgatagaaaa aagttggaac ttaacctcta
    14821 aaaaatgaaa tattttaata attttcatga actttcaatt agctaaatat tctttactga
    14881 agaaattttc agaaaatata gaatttacca caccagggga atatggtgcc atcttcaaat
    14941 acctgattga gaatgtcaag acggatcgtc agatcatctg ttcgcctcac tgtcatgatg
    15001 acctcggaat ggcagtggca aatagccttg ctgctgtcaa gaatggtgca ggacgtgttg
    15061 aagggactat caatggtatt agggagcgag ctggaaatgc tgctttggaa gaaattgcag
    15121 tggctctcaa tattcgccaa gattactacc aagtagaaac cagtattgtc ctaaatgaga
    15181 ccatcaatac gtcagaaatg gtttctcgtt tctctggtat tcaccaagat ggagtcctta
    15241 aaaatcctct cacttatgag atcatcacac ctgaattggt tggtgttaag attccgcttg
    15301 gaaaattatc tggtcgccat gcttttgttg agaaactgag agaattggcc ctagatttta
    15361 cagaagagga tatcaaacca ctctttgcta agttcaaggc actggccgat aagaagcaag
    15421 aaatcacaga tgcagatact cgagctttgg tagctggaac catggttgaa aatccagaag
    15481 gcttccactt tgatgattta caacttcaaa ctcatgcaga taatgacatt gaagcgctcg
    15541 ttagcctagc caatatggat ggtgagaaag tcgaatttaa tgcgacaggg caaggttccg
    15601 ttgaagcaat ctttaacgct atcgataagt tctttaacca atctgttcgt ttggtgtcct
    15661 acactatcga tgcagtaaca gatggaatcg atgcccagga tcgggttttg gtcactgttg
    15721 aaaacagaga tatagaaacc atctttaatg cagcagggct tgattttgat gtgttgaagg
    15781 cttctgctat tgcctatata aacgctaata cctttgttca aaaagagaat gcaggtgaga
    15841 tgggatgcag tgtttcttac catgatatgc ctagtgtgta aaggagaagg ctatggcaaa
    15901 gaaaatagta gctctagtag gagacggaat tggcccagaa atcatggagg ctggtttaga
    15961 agttctggag gctctagctg aaaaaacagg ttttgactat gagattgaca gacgaccgtt
    16021 cggaggtgca gatattgatg cagcaggacc tcccttacct gatgaaaccc ttaaggcaag
    16081 tagggaagca gatgctatcc tactagtagc tatcggtagt cctcagtatg atggagtagc
    16141 ggttcgccct gaacaaggcc tgatggctct ccgtaaggaa ctcaatcttt acgctaatat
    16201 tcgtcctgta aaaatctttg acagtctcaa gtatttgtca ccactcaaac cggaacgaat
    16261 ttctggtgta gactttgtcg tggtgcgtga attgacaggc gagatttact ttggagatca
    16321 tattcttgaa gagcgcaaag cgcgtgatat caacgactat agctatgagg aagtggagcg
    16381 gattattcgc aaagcctttg aaattgcaag aaatcgcaga aaaatcgtta ctagtatcga
    16441 taagcaaaat gttctagcga cctcaaaact ctggcggaaa gtagctgagg aagtcgcaca
    16501 ggatttccca gatgtaacct tggaacacca gctggtagac tcagctgcta tgcttatgat
    16561 taccaatcct gctaagtttg atgttattgt aacggagaat ctttttggag atattttatc
    16621 tgatgaatca agcgtcttat ctggtacact tggggttatg ccatcagcca gtcattctga
    16681 aaatggacca agtctctatg aacctattca cggttcagca cctgatattg caggtcaagg
    16741 aattgccaat cctatttcca tgattttatc agttgtcatg atgttgagag atagtttcgg
    16801 acgttatgag gatacagagc gtatcaaacg tgctgttgag acaagtctgg cggcaggaat
    16861 tttaacgaga gatataggag gtcaggcttc aacaaaggaa atgatggaag ctattattgc
    16921 aaggttatga agttagacga aaaaattact ctagtccttt tgatttggaa tgtcatcatt
    16981 ttcttgattt atggcattga caaattcaag gcaagaagaa gagcttggcg catccaagag
    17041 aaaatcttac tcattttagc ccttacttgt ggtggttttg gggcctggtt agctggaatc
    17101 acttttcacc acaagactcg aaaatggtac tttaaaacag tttggtttct tgggatggtg
    17161 accacactag tagccttata ttttatttgg aggtaatgga tggcagggtc ttcgagggaa
    17221 cacgctgctt gggctctagc gaactatggt tttaaggtcg tgattgcagg aactttcggt
    17281 gacattcatt acaataatga actcaataat ggcctgttgc caatcgttca gcctagagag
    17341 gttagagaga aattagccca gctaaaacca accgaccatg taactgtgga cttggaacaa
    17401 caaaaaatca tctcaccagt tgaagaattc accttcgaga tagatagcga gtggaaacat
    17461 aaactcctaa atagtttgga tgatatcggt attaccttgc agtatgaaga gttgattgct
    17521 gcttatgaaa aacaacgacc agcctactgg caggattaga aaaaatagaa aaggaaatat
    17581 agtaaactga aataagatgt aaacaaatga attggagctt aacatccatt tccagcaatt
    17641 ttttagaaac tacagtggac tattctggat tcaacacatt ataaaattat gacaaaacac
    17701 attcacaaga aggctacgac attttaaaag gtgagggcgg atgtatcgct tgccctacta
    17761 aagttggtta cattatcatg accagcaaca aggcagaact tgagcgtaag ttcgcagcca
    17821 aagaacgtaa gcgtaacaaa ccaggtgttg ttctctgcgg tagcatggat gaacttcgcg
    17881 ctttagcgca actcaaccca gaaattgaag cattctacta aaaacattgg gatgaagata
    17941 ttcttcttgg ttgtatcctt ccttggaaac cagaagcctc tgaaaaactc aaagcatacg
    18001 gggatggccg tgaagaactt atgactgatg tacgtggtac tagctgtttt gttatcaagt
    18061 ttggaaaagc aggtgaacaa ttggctgcca agctttggga agaaggtaaa atggtctacg
    18121 cctcatctgc ttcaatgaca aaacgattga aactcgctat gagagcaagg tgtaatggtg
    18181 tctatggtcg ataaggatgg caaactcatc ccagaacaag gaggagcacg ttcaacctca
    18241 ccagcaccag ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca
    18301 gatactttta actcatggga ctaccgtcag gttgagtatt attaggatag agaagaagtc
    18361 tagtgttaag gacattacag ctcataatac taggcttttt tatagaaatt cttttctttt
    18421 tctataggat atggtattct atgtagaaaa tatatgttaa taagtaatgc caatatttaa
    18481 acatcattag taaaaggagt tagattgatg aataaaagaa aagttagttt agaagatttt
    18541 tataaatggt atagtctaaa taaagaagag ttattaaata aggcaactgt tggtgaaaag
    18601 tttaatgata aattaaaaga agagtttctc caggaatggc ctttggatag gattttaaca
    18661 atgtcaatcg atgaatatgt aataggaaag ggacagcaaa ataagtcttt atgctacgct
    18721 cttgagaagg gaaaatacaa aaatctattt cttggaattt ctggtggctc agcttcaaaa
    18781 tttggtattt attggaataa aaaaacaaac aaatataaag atcaagctaa taatgagatt
    18841 tcagagttgg atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat tatcaaagaa
    18901 ggtattcgtt ttaactttga aaatcctatt tttgatatga aaagatcaac aaatgaattt
    18961 attggtcgtt ctgctatggt gacaaaatta ctttgtatct attctgaggg agatcctttc
    19021 tttggtgtaa atattaatag tcagaaagaa ttttggaacc actttgtttc tcagacaaat
    19081 caaggtggac cttatctgca aaatcataaa ataattgaac tggtgtccaa aacttatcct
    19141 gagttggagc catcgaaatt aggaactatg ctttttgagt attctaagct ttttatggaa
    19201 aataaaggaa gacaatagta caatggattc atcaaacaat tttcgtcatc aattaactca
    19261 atctctatta aagtctccaa accttatcct tcgtggtgct cctggcacag gaaagactta
    19321 tcttgctaaa gaaattgcca aagaattaac ggatggcaac gaagatcaaa tcggatttgt
    19381 acaatttcac ccatcatatg attatacgga ttttgtagaa ggtttaagac cagtatcaaa
    19441 tggggatgga gctattgagt ttaggctaca ggacggtatt tttaaagatt tttgtcagaa
    19501 agcaaaagaa acccaattga ttggaggaca agataatttt gatgaggctt gggattctta
    19561 cttagaatat ataaatgttg ctgaagaaaa agaatatata acaaaaacat cttacttatc
    19621 tgttaatagt agacaaaatt tgtcagtaaa ttatgatagt ggtgttccag gatggtcact
    19681 acctagcaaa tatgtttacg agttgtataa agataaaaat tataataagc aagaatacta
    19741 caaaagtggt ggaaaaactg tcctagaaac attgagaaag agatttggtt tgaaagacta
    19801 tgtttcccca acagaaattg atactgataa gaaattcgtc ttcatcatcg atgaaatcaa
    19861 tcgtggggag atttctaaga tttttggcga actctttttc tctatcgacc ctggctatcg
    19921 tggtgaaaaa ggaatcaacc gtgaggactt attccagctg atttcctatt cttatatttt
    19981 aaaagctgag aaggctggac tgatttttcc tagtatggag cagtcagtaa atagtgaaat
    20041 aggaaaagta gctggctatg gagctcaatt gaagaagtgg tctattcgaa tccctcagaa
    20101 tgcctcattc tatagtacat tttgtaaaat gatggaaaat tcagaagaaa attttaaagc
    20161 gattattgat gaagaagtgg ggagaaaata atttcccctc tttcttttat ttttaacaca
    20221 agtaaaaccc gaacgatata ttttaattca taaaataatt tgacaaaaac tgtactttga
    20281 tttataataa attaaggaaa cgtcggaaaa ggcgtagtga tgcaagagca taggtaggtc
    20341 attacaaaag aaacgagaca tcgatatgtt aaatgaattt ccaatttttg attacgaaga
    20401 tattcaattg attccaaata aatgtgtcat taaaagccgt gcagaagcgg atacaagtgt
    20461 cactttagga aatcacacct ttaaactacc tgttgtgcca gcgaatatgc agacgatttt
    20521 ggatgaaaat gtagcagagc aactggctaa aggtggttac ttctacatta tgcaccgttt
    20581 tgatgaggta ggacgcattt cttttattaa acgaatgcac gatcaagggc tcattgcttc
    20641 tatctctgtc ggtgttaagg attatgagta tgattttgtt agccagctca aggctgatgc
    20701 tcctgagtat atcactattg atattgctca tggtcatgcg gatagcgtga tttctatgat
    20761 tcaacacatc aagaaagaat tgccagatac ctttgtcatt gctggaaatg tgggaacacc
    20821 agaagctgtg cgtgaattgg aaaatgctgg tgcagatgct actaaggtcg gaatcggtcc
    20881 tggtaaggtt tgtatcacca aggttaagac tggttttggt acaggtggtt ggcagttggc
    20941 tgctctacgc tggtgtgcca aggctgcgcg taaaccgatt atcgctgatg gaggaattcg
    21001 tactcacggt gatattgcca agtctatccg cttcggtgct agcatgatca tgattggttc
    21061 cctctttgca ggacatattg aaagtccagg gaaaacgatt gaagtcgatg gtgaacagtt
    21121 caaagaatat tatggttcag cctcacaata tcaaaaaggt gcttacaaaa atgtggaagg
    21181 caaacgtatc ttgcttcctg ctaaaggtca tctgcaagac actttaactg agatggaaca
    21241 agaccttcaa agtgctattt cttatgcagg tggacgtcag gttgctgacc ttaaacacgt
    21301 tgattatgtg atcgtgaaaa actccatctg gaatggggat gcttcccact aagacggggt
    21361 ctttgaccaa aaaacttgtt attagagcaa atttctgtta taataaaaca agtttccacc
    21421 cttagtgtaa tggatatcac gtaagattcc ggttcttgag atgggggttc gattccctca
    21481 gggtggatgt aaacattcta aaaagccttt aatagggctt ttttctttac actgctctaa
    21541 atttactgct aaaactgaga atctctgtct aaagaatttc caaatgcttt ccagtcccgt
    21601 tttagagtga ctcagggggc tttttttgat ataataaaaa ggactgttat cagttagaaa
    21661 gaggttggta tgaaagaatt acaaactgta ctaaagaacc attttgcaat cgaatttaca
    21721 gacaaaaagt tactggaaac tgcctttact catacgagtt atgccaatga gcaccgcctc
    21781 ttaaaaattt cacataatga acgcttggaa tttttaggag acgctgttct acagttattg
    21841 atttcagaat atctgtataa aaaatatcct aaaaagcctg aaggtgacct atcaaaactc
    21901 cgtgctatga ttgtccgtga ggagagttta gctggttttg cgcgtgattg ccagtttgac
    21961 cagtttatca agttgggtaa aggggaagaa aaatctggtg gtcgcaatcg tgacaccatt
    22021 cttggtgatg cctttgaagc ctttcttggt gcccttcttt tggataagga tgtggccaag
    22081 gtcaaggaat ttatctatca agtcatgatt cctaaggttg aagcaggcga atttgagatg
    22141 attacagact ataaaaccca tctccaagag ttacttcagg tcaatggtga tgtggctatt
    22201 cgttatcagg tgatttctga aacagggcct gctcacgata aggtctttga tgtagaagtt
    22261 cttgttgaag gtaagagtat cggtcaaggc caaggtcgtt ctaagaaatt agcagagcag
    22321 gaagctgcca aaaatgccgt tgagaagggg ctggattcat gtatttaaag gaaatcgaaa
    22381 ttcaggggtt caagtctttt gctgataaga ccaaggtcgt ttttgaccaa ggtgtgacgg
    22441 cagttgttgg acccaatgga tctggaaagt ccaatattac agaaagtctg cgttgggctt
    22501 tgggggagtc tagtgtcaag agtctccgtg ggggcaagat gccggatgtc atctttgctg
    22561 gaacagaaag tcgcaaaccg ctcaattatg cttctgtagt tgtgactctg gataatcatg
    22621 acggatttat caaggatgca ggtcaagaaa tcagggtgga acgccatatc tatcgtagtg
    22681 gagatagcga atacaagatt gacggcaaga aagtccgtct gcgtgatatt catgacctct
    22741 tcttggatac tggattggga cgagattcct tctctattat ttcccaaggg aaggttgagg
    22801 agatttttaa ttccaagcct gaggaacgac gagctatttt tgaagaagct gctggagttt
    22861 taaaatacaa gactcgcaga aaagaaaccg agagtaaact gcagcaaact caggataatc
    22921 tggaccgctt agaggacatt atctacgagt tggataatca aatcaagcct cttgagaagc
    22981 aagctgagaa tgcccgtaag tttttagact tggaaggaca acgtaaggct atttatttag
    23041 acgttctggt tgctcaaatc aaggaaaata aggctgaact agagtcgaca gaagaagagt
    23101 tggctcaggt tcaagaactc ttgatgagtt attaccaaaa gcgtgaaaaa ttagaagaag
    23161 aaaatcaaac tcttaaaaag caacgccaag atttacaggc tgaaatggcc aaagaccaag
    23221 gcagtttgat ggatttgacc agtctgatta gtgacttaga gagaaaatta gccctatcga
    23281 aactggaatc tgagcaagta gccctcaatc aacaggaagc acaagcccgt ttggctactt
    23341 tggaggataa gagaagttca ctcagccaag aaaaatctga taaagaaagc tctttagccc
    23401 tcttggaaga aaatctagtc caaaataatc aaaaactcaa tcgattagag gctgaattgc
    23461 tagctttttc agatgatcct gatcagatga ttgagctctt acgtgaacgc tttgtggccc
    23521 ttttacaaga agaagcagat gtctcaaacc aactgacccg tattgagaat gagttggaaa
    23581 atagtcatca gctttctcaa aaacaagcag atcaactaga aaagctgaaa gaacagttgg
    23641 ctacagctaa agagaaggct ggtcagcaaa aggctgagct tgaaactgcc aaggagcagg
    23701 ttcagaaatt attggccgac tatcaagtct gtgctaagga gcaagaggag cagaaaactt
    23761 cctatcaagc tcaacaaagt caactctttg accgtctgga tagtctcaaa aacaagcagg
    23821 ctagagcgca aagtttggaa aatatcctga gaaatcatag taacttttat gcaggtgtta
    23881 agagtgttct ccaagagaaa gatcgtctag gtgggattat tggagcagtt agtgagcacc
    23941 tgacctttga tatgcattat caaactgccc tagaaattgc gcttggagcg agtagtcagc
    24001 acattattgt agaagatgag aatgcggcaa ccaaagccat tgatttactc aaacgaaaca
    24061 gatctggtcg tgcaaccttc cttcctttga ccactatcaa ggctcgtacg atttctagtc
    24121 agaaccaaga tactattgct gcaagtccag gatttctggg catggcagat gagctggtta
    24181 ctttcgatac tagactggaa gccattttca agaatttgct agctacaacg gccatttttg
    24241 ataccgtgga gcatgcgcgt gcagcagcgc gccaggttcg ttatcaggtt cgtatggtga
    24301 cattggacgg aacagagctg cgcacaggtg gttcttatgc aggtggagct aatcgccaga
    24361 ataacagtat tttcatcaag ccagaactgg agcaattaca aaaagaaatt gctgaagaag
    24421 aagcaagttt gcgttcagat gaagtgagtt tgaagaactt gcaagatgag ctagctagat
    24481 tgacagaaag attagaagcc atcaaatctc agggagagca ggctcgtatt caggagcaag
    24541 gcttgtccct cgcctatcag cagaccagtc agcaagttga agagctagaa actctttgga
    24601 aactccaaga agaggaatta aatcgtcttt ctgagggaga atggcaagcg gataaggaaa
    24661 aatgccaaga gcgccttact acaatcacta gtgaaaagaa taatctggaa gctgagattg
    24721 aagagattaa gtctaataaa aacgccatcc aagaacgtta tcaaaacttg caggaagagc
    24781 tagctcaagc tcgtctactt aagacagaac tgcaagggca aaaacgttat gaagttgctg
    24841 atattgaacg cttaggtaag gaactagata atcttgatat tgagcaagaa gaaattcagc
    24901 gccttcttca agaaaaggtt gacaatcttg agaaagttga tacggatttg ctcagtcaac
    24961 aggctgatga agccaaaact caaaaaacaa atctccaaca aggtttgatt cgcaagcagt
    25021 ttgagttgga tgatattgag ggtcaactgg atgatattgc tagtcatttg gatcaggctc
    25081 gccagcagaa tgaagagtgg attcgcaagc aaactcgtgc tgaagccaag aaagaaaagg
    25141 ttagcgagcg cttgcgccat ctacaaaatc aattaacaga ccagtaccag attagctata
    25201 ctgaagcact agaaaaagcg catgagttgg aaaatctcaa tctggcagag caagaggtgc
    25261 aggatttaga gaaggctatt cgctcactgg gacctgtcaa tttagacgct attgaacagt
    25321 acgaagaagt tcacaaccgt ctggatttcc taaatagcca acgtgatgat attttgtctg
    25381 cgaaaaacct gcttcttgaa accatcacag agatgaatga tgaggtcaag gaacgcttta
    25441 aatcaacctt tgaggccatt cgtgagtcct ttaaagtgac cttcaagcag atgtttggtg
    25501 gaggtcaggc agacttgata ttgactgagg gcgacctttt aacagctggt gtggagattt
    25561 ctgttcaacc tccaggtaag aaaatccagt cgcttaacct catgagtggt ggtgaaaaag
    25621 ctctatcggc tcttgccttg cttttctcca ttattcgtgt caagaccatt ccttttgtca
    25681 tcttggatga ggtagaggct gcgctagacg aagccaatgt taaacgtttc ggggattatc
    25741 tcaaccgctt tgataaggac agtcaattta ttgtcgtaac ccaccgtaag gggaccatgg
    25801 cagcggccga ttctatctat ggagtgacca tgcaagaatc gggtgtttca aagattgttt
    25861 cagttaagtt aaaagattta gaaagtattg aaggatgaca attaaactag tagcaacgga
    25921 tatggacgga accttcctag atgggaatgg acgctttgat atggatcgtc tcaagtctct
    25981 cttggcttcc tacaaggaaa aagggattta ctttgcggtg gcttcgggtc ggggatttct
    26041 gtctctggaa aaattatttg ctggtgttcg tgatgacatt attttcatcg cggaaaatgg
    26101 cagtttggta gagtatcaag gtcaggactt gtatgaagcg actatgtctc gtgactttta
    26161 tctggcaact tttgaaaagc tgaaaacgtc accttatgta gatatcaata aactgctctt
    26221 gacgggtaag aagggttcat atgttctaga tacggttgat gagacctatt tgaaagtgag
    26281 tcagcattat aatgaaaata tccaaaaagt agcgagtttg gaagatatca cagatgacat
    26341 tttcaaattt acaaccaact tcacagaaga aacgctggaa gctggtgaag cttgggtcaa
    26401 tgataatgtc cctggtgtca aggctatgac aactggcttt gaatctattg atattgttct
    26461 ggactatgtc gataagggtg tagctattgt tgaattagct aaaaaacttg gtatcacaat
    26521 ggatcaggtc atggcttttg gagacaatct taatgactta catatgatgc aggttgtggg
    26581 acatcctgta gctcctgaaa atgcacgacc tgaaatttta gaattagcaa agactgtgat
    26641 tggtcaccat aaggaacggt cggttatagc ttatatggag ggcttataat ggcagatata
    26701 aaattgattg cattggactt ggacgggacc ttgctgacta ctgataaaag gctgacggat
    26761 cgtaccaagg aaaccttgaa agctgcgcgt gatcgtggta tcaaggtcgt attgacaact
    26821 ggtcgtccct taaaagccat ggatttcttt ctccatgagt tagggactga cggtcaggaa
    26881 gatgagtata ccattacttt taatggtgga ttagttcaga aaaatacagg agaaatcctt
    26941 gataaaacag tcttttcata tgatgatgtg gcacgtttgt atgaagaaac agagaaatta
    27001 tcactgcctc tcgatgccat ctcagaagga acagtttatc aaatccaatc ggaccaagaa
    27061 agtctttatg ccaaattcaa tccagctttg acctttgttc cagtggactt tgaagactta
    27121 tctagtcaaa tgacctacaa caaatgcgtg actgcctttg ctcaagaacc cttggatgca
    27181 gccattcaga agatttctcc agaattgttt gaccaatatg aaatctttaa atcacgtgaa
    27241 atgttgctag aatggtcacc aaagaatgtt cataaagcaa caggtttggc aaaactaatc
    27301 agccatcttg gaatcgacca aagtcaagtg atggcttgtg gtgacgaggc caatgacctc
    27361 tctatgattg aatgggcagg tcttggtgtt gctatgcaaa acgctgttcc tgaagtaaag
    27421 gcagccgcaa atgtagtgac gccgatgacc aacgatgagg aagctgtcgc ctgggctatc
    27481 gaagaatatg tgctaaagga gaactaagat atgggattgt ttgaccgtct attcggaaaa
    27541 aaagaagaac ctaaaatcga agaagttgta aaagaagctc tggaaaatct tgatttgtct
    27601 gaagatgttg atcctacctt cacagaagtt gaggaagttt ctcaggaaga agcagaggtt
    27661 gaaattgttg aacaagctgt gttccaagaa gaggaaatcc aagacacagt tgaagaaagt
    27721 ctggatttag agccagttat agaagtttct caaaaagaag tcaaagaatt tccacactca
    27781 gaagaaggga atactgagtt tctagagact gtagaagaaa ataattctga aattcttgaa
    27841 gcagaaaggc ctcaaacaga agaaactgtt caggaaaaat atgaccgcag tcttaagaaa
    27901 actcgcacag gtttcggtgc ccgcttgaat gccttctttg ctaacttccg ctctgttgac
    27961 gaagaatttt tcgaggaact ggaagaactg ttgattatga gtgatgttgg tgtccaagtc
    28021 gcttctaact taacggagga actacgttac gaagccaagc ttgaaaatgc caagaaacct
    28081 gatgcacttc gtcgtgtcat cattgagaaa ttggttgagc tttatgaaaa ggatggtagc
    28141 tacgatgaaa gcatccactt ccaagataac ttgacagtta tgctctttgt tggtgtgaat
    28201 ggtgttggga aaacaacttc tatcggaaaa ctagctcacc gctacaaacg agctggtaag
    28261 aaggtcatgc tggttgcagc agataccttc cgtgcgggtg cagtagctca gctagctgaa
    28321 tggggccgac gagtagatgt tccagtagta actggacctg aaaaagctga tccagccagc
    28381 gtggtctttg atggtatgga acgtgccgtg gctgaaggta tcgatattct catgattgat
    28441 actgctggtc gtctgcaaaa taaggataac cttatggctg agttggaaaa gattggtcgt
    28501 attatcaaac gtgttgtgcc agaagcacca catgaaacct tcttggcact tgatgcatca
    28561 acaggtcaaa atgccctagt acaggccaaa gaattttcga aaatcacacc tttaacggga
    28621 attgttttga ctaagattga tggaactgct cgaggaggtg tggttctagc cattcgtgaa
    28681 gaactcaata ttcctgtaaa attgattggt tttggtgaaa aaatcgatga tattggagag
    28741 tttaactcag aaaacttcat gaaaggtctc ttggaaggtt taatctaatc agaagcaaaa
    28801 atcctgcaag gcataaactt gcaggaaatt tttttattct aagcgaccat cttgacgata
    28861 ggcgatatct ggttgccaag tccatttggc accgaatttt tcaagtaggt caaagctggc
    28921 ttgaggtccc atgcttccag ctttatagtc atgaagtggg gcaccatttt catcccagag
    28981 ctcttcaata cggtcaatca acttccatga tgcaccaact tcatcccagt ggctaaagtt
    29041 agttgagttg ttatttagga catcataaat caatttctcg tatggttctg gagaagcacc
    29101 agttgcagtc gcatctgtac ggtaatcaag tgagttagga gccaagttaa attcttctcc
    29161 tacttgcttc ccatttaggc taagagagaa gccttctgtt ggttgaatat agatggtcaa
    29221 aatatttgga gcaagtggtt ctccaaagat agaatccatt tgtttaaaga cgatgttgac
    29281 atgagttcct ttttcagtca gtcgtttacc tgtacggaaa aagaaaggaa cactacggaa
    29341 tcgatcgctg tctacaaaga aggcaccaga tgtaaaggtt tcagttgttg attctggatt
    29401 cacatttggc tcgctacgat aagagatgta tttcatgcca tcaatcttac cagagcggta
    29461 ttgcccacgg ataaagtgtt ctttgagttc ttcatcagtt ggatgataga ggtttttaaa
    29521 gaccttaatc ttttcagcac gaatctcgtc ttttgtgaag cttgctggtt tgtccatggc
    29581 gaggagcgaa agaagttgta gagtgtggtt ttggaccatg tcacggaggg caccggattg
    29641 gtcatagtag ccaccacgtt cttctacacc caagcgctcc gcaaaggtaa tttgaacatt
    29701 gtcgataaaa tccttgttcc aaacgttttc aaaaatcaag tttgcaaagc gaactgcaaa
    29761 gatgctttgg atcatttcct taccaagata atggtcgata cggaaaattt gttcttcgtc
    29821 aaatgttgct aggagttcgt cattcaactt gcttgcagtt gcgtaatctg taccaaatgg
    29881 tttttcaacg atcaagcgct caaaaccttt gccatcgaca atgttttcag atttgaggtg
    29941 tttggcaatg gttccaaaga actgaggtgc catagacaag aagaagagct tattgtgttc
    30001 agcttggtat ttttcattaa gctcagcttg taattgacgc aaagcaatat aatgttccga
    30061 atcattgaca tcatggcttt gatagtagaa gtggctagca aattcttggg cttgctcggt
    30121 actatctgcc aaatcaagga tggactcgac aactacagat tcaaaatatt ccttactcca
    30181 aggtctacgg gcagttccaa taacggcaaa gtgcttggaa agattgccgg atttatatag
    30241 tctaaaaagg gaagggtaga gcttgcgttt agccaggtct ccactcgcac cgaaaattgt
    30301 aacaataacc ttagatgaca tctagctacc taatttctat ttttattcct agtcttgcta
    30361 ggtatgagga aacctcattt cataaactta attctaacat aattttccga aaaatcaaaa
    30421 attccaatac gaagtagaaa aactgcaagg aaatccttac agtttgagtt tagacgttta
    30481 agaccttatc taagaactct ttcagacgag ggtgttgtgg gttatcaaag atttggtcag
    30541 gtgttccgtc ttcaaggaac tcgccatctg cagtaaagat aacgcggttg gcaacctgac
    30601 gagcaaatcc catctcatgg gttacgataa tcatggtcat accttgctca gccaattcct
    30661 tcataacgtt aagtacgtct ccaaccatct cagggtcaag ggcagaagtt ggttcatcga
    30721 agagcatgat gtctggattc attgctaggc cacgagcgat ggccacacgt tgtttttgac
    30781 cacctgatag gctatctgga ttggcattag ctttatctgc tagtccaacc ttttcaagca
    30841 actccattcc caattcctca gcttcttcct tagtcatcaa cttgtgctca ataggagcaa
    30901 aggtgatgtt gtccaataca gacatatgag ggaagaggtt gaagtgttgg aataccatgc
    30961 cgatattttc acggacgtgg tcaacattgg ttgttttttc agttaaatca tagccgttca
    31021 cagtgatgtg accgctagtg acttcttcta aaagattgag gctacggagg aaagttgact
    31081 taccagaacc tgaaggaccg atgatacaaa caacatctcc ttcatagaac ttagtcgtaa
    31141 ttccttttag gacttcattt tttccatagt gcttgtgtaa atcatttaca tcaattttta
    31201 attttgccat taacgaatcc tcttttctaa gcgtttcgct agtctagtca aaagtgtgat
    31261 aattacaaga tagaagatag caaggattgc atacatcttg aaactttggt agttacgagc
    31321 aatgataatc ttaccagttt ggaagagttc aaccaaaccg atagcagata cgatagttgt
    31381 atctttaaga gcgataacga attggttgac aaagtttggc aacatcaatt tagttgcttg
    31441 tggcaagata atcttacgca tggtttttcc ataagagata cccaagcttc ggctggcttc
    31501 catttggcca actggaacgg cctgaatacc accacgaacg atttcagcga tataagcagc
    31561 cgcattgagt gagagggcaa tggttccagc tacaaagtcg ttaattgggc tttgttggcc
    31621 tgtgatagac tcgatgaagt ttggaattcc ccagaagatg aaggctgcaa gaatcatcaa
    31681 tggaatacca cgaataacgt caacgaaaat ctcagagatg acgcgaagag atttgtatgg
    31741 gctaacgcta aacataccga agataattcc gatgacaatg gcaatagcaa atgagataag
    31801 agctagagca agagtgatac caagaccgct aaggagttgt ttgtagttgt tttgaagcaa
    31861 gccccagagc gttgtttcgt caacagtact tgttgaagca gttgaagatt cgctagctag
    31921 gtatttgtca agaatctttt ggaattcacc gtttgcttta aggtttgcaa gtccgttgtt
    31981 gaacatttca atcagttctg gatttgctcc ttttttaacg gcaaaggctg tttcaccgat
    32041 tggagttcca gagattggag ttttcaattt ttgaccttgg ctgatagaat atttgagaac
    32101 aggttcatca tccataacgg catcaatggc accagtgttt aaactgtcat acattgaaga
    32161 accatcagca aaggttttga ttttgtaacc gtatttgctt tgattttctg ttaggaaggt
    32221 ttgagaagca gttccgtttt taacaccgac tgtctttcct tttagatctt cataagaagc
    32281 aatattgctt gattctttga caccaagaat ggtattagca gtgtagtatg attctgagaa
    32341 gtcaaaagtt gccttacgag catctgtgac agacatccca gcaatgatac catcggcttg
    32401 accagcttgg acagcactga tagcagcatc aaaaccaggg ttggtgattt caatttcaaa
    32461 accttggtct ttagcgattg ccttaatcaa ttccatatca ataccagtgt attggttgtt
    32521 tgaattttgg aaaacaaaag gtgcaaaaga agaatcgctg gcaatgatat atttagcctt
    32581 aacaggaata gcttttaatc ctgcgagagt agttgtagtt ggcactgctg aagatgatga
    32641 agcagtccat ttcttgataa ttttatcaag actaccatct tttttcattt cagccaaggc
    32701 ttggttaaat tcagtaacca ggtgctcgta tttacttcct tttttcacac cgaaagcaaa
    32761 acttcctaca gcttcaccat ccatttcaat atggagatct tgaccttggt taatggcata
    32821 ttcgataaca ggtttgtcat ccatcatggc atcgatggca ccagcactca agctgttgtt
    32881 cattaaatca ccagtgtcaa atgttttaat agtaaagccg tatttatctt tgattgtttc
    32941 aaggaaacgt tgagcggcag ttccgttttt aacaccaacg gttttgccag ttaattggtc
    33001 gtacttgcta attttgtgtg actttgtagt agcaatgaca acttttgtat catagtaagt
    33061 atcagacatg gtgaagactt tttcacgttc tttagtcttt gtcatccctg ccatgatagc
    33121 gtcggcttgc ccagcttgaa ccgcattgac tgctgcgtca aatccaggat aggacatctg
    33181 aatgttccag cctttaatct cagcgacttt gttaataatg tcaacatcaa ttcctttata
    33241 agtttgatct gaatctttaa actcaaaagg tgcataggcg gtatcagaaa caatcttaat
    33301 cgtttctgct ttggcaatac ctaatgagaa aattgggaat aaaattagca aaaatgctag
    33361 aaattttttc ttcattttta gtctcctttt ccgaatattc tctcattata tcagaaaaag
    33421 taaaaaaagg caaattgtta tatttttcgt gtcagaaaat ataacaattt gccttttctt
    33481 tcttgaattg ctattaaaaa gtgctataat aatagtatat atagaagaaa agaggacggg
    33541 gatatgaaga acaaaagaat atttaaagac ttccaagctt caaaaatgaa tttaaacatt
    33601 tacacaagcc ccttgttagc ctttgttttt gtcttcatag gagagtttgt ggcttatact
    33661 ttatatggta ttagtttgtt agctctcatc ggacttgcta gaaattttgg agaggctggt
    33721 caaaatcttg caagctactt gcagaccttg catcagagct tgacggataa aacaagtgac
    33781 tttcgtttaa ttttaggatt actggccttt ggttttattc ttaacactgt gttcagatgg
    33841 acaagaaaag ttgagaaaag acctattcga accttgggat tttatagaga gaatttcctc
    33901 agcaatcttc tgaaaggatt tagtctaggc ctggcacttt ttcttctgac cttgttaggt
    33961 ttagtggtct taggtcaata tcgtttggaa tccattcact tgaatcctta ttctcttgcc
    34021 tttgtcgtct ttactatccc attttggatt ttacagggga cagcagaaga agtggtggcc
    34081 cgtgcttggc tacttcctca attggcctca agaaccaatc taaaactagc tattcttata
    34141 tctagcctgt tctttaccct gcttcatatg ggcaattctg gcctcacccc tctatctcta
    34201 gtaaatctct ttttattcgg agttgccatg gctctttacc ttctcaaaac tgatacagtt
    34261 tggggtgttg caggtattca tggtgcttgg aattttgctc agggtaatct ctttgggatt
    34321 ttagttagtg gtcaaccgtc aggaacgtct ctgatgacct ttttaccaca aggcaatcaa
    34381 gattggctat caggtggttc ttttggcata gaaggttcca ttatgacaag tctggtatta
    34441 ctactgctga ttgtctatct tgctaataaa ttaaagaaag aaaatgaaag gatgtgactt
    34501 cggtccgtcc ttttcttcgt gaaaatacta taagtatgct aaaataggaa tagcacatgg
    34561 agagaggatt cttatgatca atcacattac agataatcaa tttaaactag tatcaaaata
    34621 tcaaccatca ggagatcaac cccaagctat cgagcagttg gtggataaca ttgagggggg
    34681 agaaaaagct cagattctga tgggggcgac tggaacaggg aagacctata ctatgagtca
    34741 ggtcatttct aaagtcaata aaccaactct ggttattgcc cacaataaaa ctctggctgg
    34801 tcagctctat ggggagttta aggaattttt ccctgaaaat gcagttgagt atttcgtatc
    34861 ctactatgat tattaccagc cagaggccta tgtcccttct agcgatacct atattgagaa
    34921 ggatagttct gtcaatgacg agattgacaa gcttcgccac tcagctacct cagccctttt
    34981 ggagcgtaat gatgttattg tcgtggcctc agtctcttgt atctatggtt tgggttcgcc
    35041 caaggaatac gctgatagtg tcgttagtct ccgtcctggt ctagagattt ctcgtgataa
    35101 actcttgaat gacttggtcg atattcagtt tgaacgtaat gatattgatt tccaacgcgg
    35161 aagatttcgt gttcgtgggg atgtggtaga gattttccca gcttcccgag atgaacatgc
    35221 ctttcgagta gaattttttg gagacgaaat tgaccgtatt cgtgaagttg aggctgtgac
    35281 aggtcaggtg ttgggagaag tggatcattt agcgattttc ccagcgacac actttgtgac
    35341 caatgacgac cacatggaag ttgccattgc aaagattcag gccgagttgg aggagcagtt
    35401 agctgtcttt gaaaaggaag gtaaactgct tgaagcccag cgtttgaaac agcggacaga
    35461 gtatgatatc gaaatgttgc gtgagatggg ctataccaat ggggttgaaa attattctcg
    35521 ccacatggat ggacggagcg aaggagagcc tccttatacg cttctcgact tcttcccaga
    35581 tgatttcttg attatgattg acgagagtca tatgaccata gggcaaatca agggcatgta
    35641 caatggagac cgttcgcgta aagaaatgct ggttaattat ggtttccgtt tgccgtctgc
    35701 tttggacaat cgtcctctcc gtcgggagga gtttgagagt cacgttcatc agattgttta
    35761 cgtttcagcg acacctggtg actatgaaaa tgaacagacc gagacagtga ttgagcaaat
    35821 cattcgtcca acgggactct tggatccaga ggtggaagtc cgtccgacta tgggacagat
    35881 tgatgacctc ttgggtgaaa tcaatgcccg cgttgaaaaa aatgagcgta cctttatcac
    35941 aactttgacc aagaaaatgg cagaggactt gaccgactac ttcaaggaaa tgggtatcaa
    36001 ggtcaagtac atgcactcgg atatcaagac cttggaacgg acggagatta tccgtgacct
    36061 gcgcttgggt gtctttgatg tcttggtcgg aattaacctg ctccgtgaag gaattgacgt
    36121 tcctgaagtg agcctcgtag ctattctcga tgctgacaag gaaggtttcc ttcgcaacga
    36181 acgtggactc atccagacta ttggacgtgc tgctcgtaac agtgaaggcc atgtcatcat
    36241 gtatgcagac acggttaccc agtctatgca acgtgctatc gatgaaactg cccgccgtcg
    36301 gaaaattcag atggcctata atgaagagca tggtatcgta ccacagacaa tcaagaaaga
    36361 aatccgtgac ctgattgccg tgaccaaggc agttgctaag gaagaggaca aggaagtcga
    36421 catcaatagc ctcaacaaac aagagcgtaa agaactcgtc aagaaactag aaaaacaaat
    36481 gcaagaagcc gtcgaagtgc ttgactttga actggcggct cagatccgtg atatgatgtt
    36541 ggaagtcaag gccttggatt aggggaatag tatgatttat ttaagaaagt taaagagaga
    36601 agatttgatg tctttatggg aaatggctta ttcacaactt aatccagttt ggaaacagta
    36661 tgatgctccc tattatgatg attatcagta tttttcaaat tttaaagaat tcgaactaca
    36721 aaaatcagaa tccattttaa gcaactcaaa tcgccttggt atttttgttg atgataaact
    36781 agttgggact gtttcgcgtt attgggtatg taaacaaaca agatggatgg aattgggaat
    36841 tggtatttat gataaaaaat tctggaacac tggtattggg aaagttgcta tgttgcagtg
    36901 gatagatagg acgtttcagg attacttgga gttggagcat ctgggtttga caacttggtc
    36961 agggaatctt ggtatgatga aacttgctga aaaattaaga atgaaaaaag aagctcatat
    37021 tccaaaagtt cgttattatc aaggtaaata ttttgatagt attaaatatg gtattttgag
    37081 agaagactgg gagaaaataa atgacggtta ttatcaaatc aatggaaact cctaaagaga
    37141 tagaaggtaa atcccttgtt cactggcaaa tgtggagaga ggcttatgat gaccttttgc
    37201 ctgcagaatt tcaggagaca atgacattag aaagatgtcg actctttagt caaaagtatc
    37261 cagaaaatac attgattgcg ataggtgatc tgaaggtagt tggttttatc agttatggta
    37321 actttcgtga tgagactatg caagctggtg aaattattgc tttatatgtt ttaaaagact
    37381 attatggaaa aggtatcgca caaaagttaa tgaaagcagc tttgactgct cttaatcatt
    37441 tttctgaaat tttcttatgg gtattgaaag ataacaagcg cgccattgct ttctatcaaa
    37501 aaatgggttt tacttttgat ggacaagaaa aaatacttga acttggaaag cctataaagg
    37561 aaaaacgaat ggtgttctat tctaaataat tttaaaaaag taaaagataa tatctctggt
    37621 agtaagtctg aaaatttaat aaattagaaa gcgagtaaat ttatgtcccg ttcccaatta
    37681 acaattttaa caaatatctg tctgattgaa gacctcgaaa ctcagcgcgt ggtgatgcag
    37741 tatcgcgccc ctgaaaacaa tcgctggtct ggttatgcct ttcctggagg tcatgtagaa
    37801 aatgatgagg cttttgcgga gtctgtcatt cgtgaaatct acgaagaaac agggttgact
    37861 atccaaaatc ctcaacttgt cggcattaaa aattggccac tagatacagg tgggcgctat
    37921 attgtcattt gttataaggc gactgagttc tctggtaccc ttcaatcttc agaagaggga
    37981 gaagtttctt gggtgcaaaa agaccagatt ccaaacttaa atctggccta tgatatgcta
    38041 ccattgatgg aaatgatgga agctcccgac aagtcagagt ttttctaccc tcgccgtaca
    38101 gaagacgatt gggaaaagaa aatcttctag tcttttacta aataacctag ctgatccaag
    38161 gcctcctcga tatagtggag gtcttgttgt gtttcggctt cgactaggtg gtaatggatg
    38221 ccatctgtca attcagatag aggtctaaag tcagaatgct cgacttgttc tagaaaatgt
    38281 tgcacatctc tgcgacaaga cagtttaagc aaggtttcaa tttctccata aacgggatgg
    38341 tcaatcaagg tattctggac atgcccacca ttatcgacaa tagcaaggag ttcctgaccg
    38401 atttcttcaa cttcatgttt cactttgaaa agtttgtgaa cataaggatt ggtatcaatt
    38461 tgcttataga tgtagccacg attggtggat aggataggag cgccatcggc tctcaaaatt
    38521 gcaatgtcct gcacaatgac ctgacgtgtg acatgaaaat gttccgccaa actttggcca
    38581 ttaagggctt taggagcttc tttcaagagt tggagcaggg cttgtttgcg atcttttgtc
    38641 atagcttttc cttttaacgg cgttttcgaa gcactttata gacagctagt gctaatgtat
    38701 agtctaccat actatggata attgtgccaa atccaactag tacaaataga acatagaaca
    38761 tattttctac attggtaccc gaagttgcgt aaaaaaggac acaggctaat acttcagcaa
    38821 gggcatgaac aacagccaaa acaaaattga aaacccagga agattttggt ttatctaggg
    38881 tatcggggaa tttttgtagg taaagagctc ctaaagcacc aaaagatata tgggaaaaag
    38941 cccgaaaaac gataaccatg ggatagccag ccatcaaaaa tccaaaacta gaggctagga
    39001 tgacaaaaac tgccatcaag ggcgacaaga acatggctat aaaaatagcg atgtggctcc
    39061 ccaaagtata ggaagcaggt ggaatgacaa tcttgaaagg cataacaatt ggaatcaaaa
    39121 tcgcaatagc cgttaaaagg gctgtcattg tcataaattg tgtctttttc cgtgtattca
    39181 caagaatctc ctttttaact gcatatacac tagtatggta caataaacca gacaataaag
    39241 caagaattta cttgggttta tagatcattt tttagttaaa agttatagta gatggaaact
    39301 agaatagtcc acctctactt ctaaaacatt gttagcgatt tgactgtcct gatcgatttg
    39361 tcctgttctt atttcgtttt actatagtaa agatttcatt aaaaagaaac tgtatagagc
    39421 aaaatctcca ccttcaggtt tgaaagcgga gattgttttt attttttcaa ggtttgtagt
    39481 cgtggaacaa tggctagggt tagaattgca gaaatgacca attcagcaat tgaatttgtt
    39541 gagataacgg ttgccagaag aagttggata tttccattat aaacatttcc aaataggaag
    39601 aagattcctc caaggacaaa gatagtattt gtcaaggaac caagggctcc agctaaaatc
    39661 agaccagtct tgtttttcat cagtttatag actaagtaag gagttaaacc aatcaaaata
    39721 cgtgggacga tggcaatgat agctgagtag atgtttccgt ttggtacgaa gggagagaag
    39781 aggtagcttg tcggtagaat cgtaatcgtg ttaaccgtca agctaagtaa tcccatcaaa
    39841 aatccaagtg taaccccaac tcgtggacca taaataatgc tggcaataat gacaggaata
    39901 tgaacaatgg tcggtttgat tggaaatgga aaaaggttaa agataagtga gctcagaaag
    39961 tgtatcacga gcatggtagc aaaaaagata gcaatgggtg caatattaga gcgttttttc
    40021 atcgatagtt tcctttattc tttctaaaat aattgtgagg tcagctaaag ctcctcgtcc
    40081 gtggtctcca caagctagta gggattcctt aggagcaatc agctgatagc cgtaggtttc
    40141 taatgttttc agattattct gagttactgg atggtcatac atttttgtat tcatagcagg
    40201 agctattagt ttgggaatat gacttggtag ggctagagct gtactggtta ccatgttgtc
    40261 cgcaaatccg tgagctagtt ttgcaatagt gttagcagtt gcaggtacca cgataaataa
    40321 atctgctttt tttccaagtt cgatatgatt gacctgatca ggatagggtt ccttcatgac
    40381 atccaagtgg acaggattct gtgagagtac ctgtagtgtc aaaggttgga taaactctgt
    40441 agcagcctga gtcattaaga cagtgacttg atggccttgt ttttttagag aactgactaa
    40501 atctgccgac ttataagagg cgattgaacc cgttacagcc aagagaatgt ttgccatagt
    40561 tttcctttct aagaatgata ggcttgaatt ttttcaagga ggagttctgc aatttcttct
    40621 ttagtctgga ctgtttgaag ctgatttttc tcaacaaata tagctcggtg ctgatctgct
    40681 gaaatttgag tcaggtcatt cgcgatgatt aaatctgctt gattcttgat aagacttttt
    40741 cgtgcaatgt caaccagatg atcttcggta acatcaacca gcagtttgaa accaatcaga
    40801 tgaatagtgg gattccattc cttgactagg gatatgattt tgggtgtctt tttaaggaac
    40861 aaaacctgaa cctcatcagt tgaagaaatc ttggcctgat gattctgctt gcttaaaaat
    40921 tcttttagat tggagctagc ctgaacttcc tcaagccctg tcatataaac aggagtgtag
    40981 tcagaaacag ccattgagtg gatcaagacc tgataatcct gaacacgttc ttgcatttct
    41041 attagaaggt ccttggtatt ggtaatttct cgaatactta ggttaggatg aggctctggc
    41101 ttcagagctc gttttgtcgt aattaaacaa acttcatgcc ctgcagaaag caaagtctct
    41161 gtgataattt tccccaagtg acctgtagaa tggttagtga tagagcggac gctatcgata
    41221 gcttcactgg taccgcccga tgtaactaaa attttcatag cactattgta cacaaaaata
    41281 agcggtaagt aaaatgaaag tgataaattt ttggtaaaaa cgaagattta ctatagtttc
    41341 aaactataaa gccatataaa atttaagaaa ggactctaaa agccttaaaa acagagatat
    41401 ttacgaacgt ttagagagtt ttaggatgtt aaaaatcttg ttttgtgata taatgaatta
    41461 tcatataaga ggttagagga attttgaatg aaaacagata ttgaaatcgc acagagtatt
    41521 gagttgaagc caattgttga tgttgtagag aaacttggta tttcttatga cgatttggag
    41581 ttgtacggaa agtacaaggc taaactcagc tttgataaaa ttcgtgcagt tgagagcaat
    41641 ccagtcggta aattgatctt ggttactgcc atcaacccaa cacctgcagg tgaaggaaag
    41701 tcgacgctta ccattggtct tgcggatgcc ttgaacaaga ttggcaagaa aaccatgatt
    41761 gctatccgcg aaccgtctct tggtccagtc atggggatca agggtggtgc tgctggtggt
    41821 gggtatgcac aagttctgcc aatggaagac atcaacctcc actttactgg agatatgcat
    41881 gctattacaa ctgccaacaa tgccctttct gccttgattg acaaccactt gcaccaaggg
    41941 aatgagctgg aaattgatca acgtcgtatc ctctgggaac gcgttgtgga cttgaacgac
    42001 cgtgcgctcc gccatgtgac tgttggtctt ggtggtcctc taaacggtat tccacgtgag
    42061 gatggttttg atattacagt tgcttcagaa atcatggcaa ttctttgctt ggcaacggac
    42121 atcgaggact tgaaacgtcg tttggcgaat atcgttattg gttatcgcta tgaccgtacg
    42181 cctgtttctg taggtgattt gcaggttgag ggtgccttgg ctttgatttt gaaggatgct
    42241 attaagccaa acttggttca gacaatttac ggtacacctg cctttgtaca cggtggtcca
    42301 tttgccaata tcgctcatgg ctgtaactct gttttggcga cgacaacagc ccttcacttg
    42361 gctgattaca ctgttactga agctggtttt ggtgcggacc ttggtgctga gaaattcctt
    42421 gatatcaaga caccaaactt gccaacatct ccagatgcag ttgtcattgt cgcaaccctt
    42481 cgtgccctta agatgaatgg tggtgtggct aaagacgctc tgactgaaga aaatgtagag
    42541 gcagttcgtg caggttttgc taacttgaaa cgccacgttg aaaatatccg taagttcggt
    42601 attccagcag ttgtagctat taacgaattt gtatctgata cagaagctga aattgcagtc
    42661 ttaaaagaac tctgtgcctc aatcgatgta ccagttgaat tggctagtgt ctgggctgat
    42721 ggagcagaag gtggagtagc acttgccgaa acagttgtta agacaattgc tgaaaatcca
    42781 gctaactata aacgtttgta cgataatgcc ctttctgtcc aagaaaagat tgaaaaaatt
    42841 gtcactgaaa tctatcgtgg tagcaaagtg aactttgaga agaaagctca aacacaaatt
    42901 gctcaaatcg ttcaaaacgg ttgggacaaa ttgccaatct gtatggctaa aactcaatac
    42961 agtttctcag acaatccaaa tgcgcttgga gcaccagaaa actttgaaat taccattcgt
    43021 gaattggtac caaaattagg tgcaggcttc atcgttgcct taactggtga tgttatgacc
    43081 atgccaggtc ttccaaaacg tccagcagct ctcaacatgg atgttgaaag cgatggaact
    43141 gtactaggct tgttctagtg gattgaaatt gactttaagt gagtttggaa ataatatcca
    43201 agctcatttt ttctcagact gcaagcagtt catcaataag atttatactc ttcgaaaatc
    43261 tcttcaaact acgtcagctt caccttgccg taggtatatg atactgactc tgtcagttct
    43321 atccacaacc tcaaaacagt gttttgagca acctgcggct agcttcctag tttgctcttt
    43381 gattttcatt gagtataagt agatagaaaa gttatatact atctattgaa aatattataa
    43441 atcagataca aagacaggtg aaaccttctg tgttatacta gagatatgtt agatttgaaa
    43501 gaatacggta tcgtcatgtg gccggaggag aaagtcattt ctttccgtga gaaacttctc
    43561 gcttggtatg atgaaaacaa aagagatttg ccttggagga gaagtaaaaa tccttatcac
    43621 atctgggtat ctgaaatcat gcttcagcag accagggtgg atacagttat cccttactac
    43681 gaaagattcc tggactggtt tccaactgtc gaaagtctgg caactgcgcc tgaggagagt
    43741 ttactgaaag cttgggaggg cttgggctat tattctcgag ttcgcaatat gcaggctgca
    43801 gcccagcaga ttatgactga ctttggtggc caatttccaa atacctatga aggaatttcc
    43861 agcttgaaag ggattggacc ttacacagca ggagccattt ccagtattgc ttttaacttg
    43921 cctgagccag ctgtagatgg taatgtcatg cgggtcttgg cgcgtctgtt tgaagtcaac
    43981 cacgatattg ggattccaag taatcgaaaa atttttcagg caatgatgga gatcttgatt
    44041 aatccggatc gtccgggtga ttttaatcaa gccttgatgg acttagggtc tgatattgag
    44101 tctcctgtaa atcccagacc tgaagaaagc ccagtcaagg actttagtgc ggcatatcag
    44161 aatggaacca tggaccgtta tccaattaaa tctcctaaga aaaagccggt tcctatttat
    44221 cttaaagcct tagttgtgaa aaattctcaa ggacaatttt tacttgaaaa aaatgaaagc
    44281 gaaaagctct tggcaggttt ttggcatttc ccctttatag aagttgataa cttttcgcaa
    44341 gaagagcagt ttgacctctt tcatcaggtt gcggaagaaa gtgtgaactt tggccccagt
    44401 ccagaagaga gtttccagca ggactatgac ctagatgttg attggcttga tgtttgtttt
    44461 gatacagtcc agcatgtttt tagtcatcga aaatggcatg tacagattgt agcaggtcag
    44521 gtgagtgact tccatgattt ttcagatagg gaagttcgtt ggctttcacc agaagaattc
    44581 aagaattacc cacttgccaa accccaacaa aaaatctggc aggcttatgc acaagccaac
    44641 ttagacagta gccaagacta gctattgtgt cttctgacta ttttttggta taatagtaga
    44701 gaaaaaggtg aacatatgaa aaaaatacta attgtagatg atgagaaacc aatctcggat
    44761 attatcaagt ttaatatgac caaggaaggt tacgaagttg taactgcttt taatggtcgt
    44821 gaagcgctag agcaatttga agcagagcaa ccagatatta ttattctgga tttgatgctt
    44881 ccagaaattg atggtttaga agttgctaag accattcgta agacaagcag tgtgcccatt
    44941 cttatgcttt cagccaaaga tagtgaattt gataaggtta tcggtttgga acttggggca
    45001 gatgactatg taacgaaacc cttctccaat cgtgagttgc aggcgcgtgt taaagctctt
    45061 ctgcgtcgtt ctcaacctat gccagtagat ggtcaggaag cagatagtaa acctcaacct
    45121 atccaaattg gggatttaga aattgttcca gacgcctacg tggctaaaaa atatggcgaa
    45181 gaactagact taacccatcg tgaatttgag cttttgtatc atttagcatc gcatacaggt
    45241 caagtcatca cgcgcgaaca cttgcttgag actgtctggg gttatgacta ttttggtgat
    45301 gtccgtacag ttgatgtgac tgtacgacgt ctgcgtgaga agattgaaga tacgcccagc
    45361 cgaccagagt atatcttgac gcgccgtggt gtagggtatt acatgagaaa taatgcttga
    45421 tttactgaaa caaaccattt ttaccagaga ttttatcttt atcctgattt tgttaggttt
    45481 catccttgtt gtgaccctct tattactgga aaatagacgt gataatattc agttgaagca
    45541 aatcaatcaa aaggttaaag atttgattgc aggagattat tccaaggttc ttgatatgca
    45601 aggtgggtct gaaatcacca atattaccaa taatttgaat gacttgtcgg aggttattcg
    45661 tctcactcag gaaaatctag aacaagagag taagaggcta aatagtattc tgttttatat
    45721 gacagatggg gttcttgcga ccaaccgtcg gggtcagatt atcatgatta acgatacagc
    45781 caagaagcaa ctggggttgg ttaaggaaga tgttctgaat agaagcattt tggaattgct
    45841 caagatagaa gaaaactatg aattgcgtga tttgattacc caaagtccag aattgttgct
    45901 agattcccaa gatatcaatg gcgaatattt gaaccttcga gttcgctttg ccttgatacg
    45961 tcgagagtct ggctttattt caggtttggt ggctgttttg catgatacga cggagcagga
    46021 gaaggaagaa cgcgaacgaa gactctttgt ttccaatgtt agccatgagt tacggactcc
    46081 tctgactagc gtaaaatcct atcttgaagc cttggatgag ggggctttgt gtgaaactgt
    46141 agcaccagac tttatcaagg tttctcttga tgagaccaac cgtatgatgc gcatggtgac
    46201 ggatctcctc catctttcac gtattgataa tgctaccagt cacctagatg tggaactgat
    46261 taacttcact gcttttatta cctttatcct caatcgtttt gacaagatga aaggacagga
    46321 aaaggagaaa aaatatgagt tggtgagaga ttatcccatc aattctatct ggatggaaat
    46381 tgatacagat aagatgacgc aggttgtcga caatatttta aataatgcta ttaagtattc
    46441 gccagatggg ggtaaaatca ctgtcagaat gaagacaact gaagaccaga tgattttatc
    46501 catttctgac cacggtttgg ggattcctaa gcaggattta ccacgtatct ttgaccgttt
    46561 ctatcgtgtg gatcgtgcta gaagtcgtgc acaaggtggt acaggtctag gactgtctat
    46621 cgctaaagaa attatcaaac aacataaggg ctttatttgg gccaagagtg aatacggcaa
    46681 gggttcaacc tttaccattg tgctccctta tgataaggat gcagtgaaag aagaagtatg
    46741 ggaggatgaa gtagaagact agaatgagtg aaataggctt taaatacagt attttagcgt
    46801 cgggttccag tggaaattct ttttatctgg aaacctcaaa aaagaagctt ttagtagatg
    46861 caggcttgtc tggcaagaaa attaccagtc tgctagctga aattaaccgt aagccagaag
    46921 acctggatgc catcttgatt acccatgagc attcagatca tatccatgga gtaggcgttt
    46981 tggctcgcaa gtatggtatg gatctttatg ccaatgaaaa gacctggcaa gctatggaaa
    47041 atagtaaata tcttggcaag gtggattctt cgcaaaagca tatttttgaa atgggtaaaa
    47101 ccaaaacctt tggagatatc gacatcgaga gttttggtgt aagccatgat gcagtcgcac
    47161 cgcagttcta tcgctttatg aaggatgata agagttttgt ccttttgaca gatacaggtt
    47221 atgtcagtga ccgtatggcg ggcattgtcg aaaatgcgga tggctatctt atcgaggcca
    47281 accatgatgt agagattttg cgatcaggtt cttacgcttg gcgactcaaa caacgaatcc
    47341 tatctgacct tggtcacctt tctaacgagg acggtgctga agctatgatt cggacgctag
    47401 gaaatcgtac taagaagatt taccttgggc atttatctaa ggaaaataat atcaaggaac
    47461 tggctcatat gaccatggtc aatcagctgg ctcaagctga tctgggagtc ggagtagact
    47521 ttaaggttta tgatacctca ccagataccg caacaccatt gacagagata tagaaagaac
    47581 gctgagaagg tgttcttttt atattgactg aacacctaaa aagtaataca atggtgttac
    47641 cattaaaaaa gggagcacaa aagatgacta ctattacatt aaaagtttct gaagctgata
    47701 aaacatttat gaaagcaatg gctaagtttg aaggagtttc cctttcggaa cttattcgca
    47761 ccaaaactct tgaagcccta gaagatgaat acgatgctcg tgtggcagat ttagcctatc
    47821 aagagtattt agaagacttg gaaaaaggag ttgaacccat tacttgggaa gaaatgatgc
    47881 atgatttagg cttgaaggat gaataatttg tataaattag ttccaacaag acgttttatc
    47941 aagcaattga aaaaattgga ccgttatacg cagaagctaa ttacaaacta tttacaaacc
    48001 aatgttttgg aaggtccaag acgacacgga aaggctttgg ttggtaatcg cgttggtcaa
    48061 tggcgctata gaattggtaa ttatcgagtt atcgtacaaa ttgtagatga tgaattagtc
    48121 gttgctactc tagaagttgg tcatcggaga gatatttatt gaattaaagc tgagtaataa
    48181 caatatagaa agtaaggaga gtaaaaattt gaagaaaaaa tggttatttg cagattatta
    48241 tgatacaaca attattttac ttgctttaat ctctgttatt ctggtattac ttggatttgc
    48301 tgagatgact gatttggaca atccgcctta tagtattatt gatttagtaa tctggggtgt
    48361 ttttgtaatt gattatagtt ggcgcttttt tattactaaa agaaaatggc gctttattct
    48421 tgaaaatatt tttgatttat tgaccattct ccctttaaat gctattttta cagtgtttcg
    48481 attaggacgt atcttccgct tagcaaggct gacaaaatta ctgaaactga ctcgtttact
    48541 tagaataatt ggacttacag gtaaactaga aagaaaaatt agtagattct tacgaacaaa
    48601 tggattgatt tatatcttgt atgttaatat ctttattgtt ctagtaggga gttcgatttt
    48661 atccgttgtt gaagaaaaat ccttctcaga tagtctttgg tgggctcttg tgacagtaac
    48721 tactgttggt tatggtgata ttgttccagt ttcccttttt gggaaatggc tagcagtttt
    48781 actgatgctt gtcggtattg gaacaatagg gatgctaaca agtgctttga cgaacttttt
    48841 tgtaaaggat aatccagatg aacagataaa acttgataaa ctcaaagacg aattatcgag
    48901 ctaaagaata ttaatagaga aacaatctga aaaaatcgaa gaactacatt gaatgataaa
    48961 agacttagtt gaaaaaatat cataaaggtg agacaaaata aaacttgatt cgaggagaaa
    49021 tcaagtaagt tttgacacaa tagaacgcat attatcaggt ataaaaactt gatactatgc
    49081 gttttataga gaaataaaat aaaatctgaa caaatcaatt aggaatttaa agcattttat
    49141 aacaacgttt tagagtaatg gggtgctatt tcaacttcaa cctactataa tacagaaaaa
    49201 aatacagaaa aaaacaactc cctgatgatt caaggagttg tctatagtta aattagtttt
    49261 tagaagcttc ttggaattct ggatttttcc atgcttcgtc aataatagct tgcaattctt
    49321 tagcagatgc ttgcattttt tgagtttctg catcgttcaa tggaatgttt actggacgaa
    49381 cgataccatg tgcaccaaca acagctggtt gaccgataaa gacattctca actccgtatt
    49441 gaccttcttg gaatactgaa agtggaagta ctgcgttttc atcgtcaagg attgctttag
    49501 tgatacgagc aagggctact gcgataccgt agtatgttgc accttttttg ttgatgattg
    49561 tgtaggctgc atcacgaaca ccttcgaaca attcaatcaa ttcagcttct tgaacatttt
    49621 gagtgtcttt aaggaattct tcaaggttta caccagcgat gttagcgtgt gaccaaacag
    49681 cgaactcaga gtcaccgtgt tcacccatga tgtaggcgtg cactgaacga gcatccacat
    49741 ccaatttttc agcaagtgct tgacggaaac gagctgagtc aagtgaagta cctgaaccga
    49801 taacgcgttc tttagggaaa ccagagaatt tccaagttga gtaagtcaaa acgtcaactg
    49861 ggttagcagc aacaaggaag atacctttga aaccagattc aacaacttga gttacgattg
    49921 atttgttgat agcaaggttt ttacctacaa ggtcaagacg agtttcacct ggtttttgag
    49981 gtgcacctgc agtgatcaca acaaggtcag cgtctgcaca gtcagagtat tgagctgcat
    50041 agattttttt aggtgaagtg aaggcaaggg cgtgactaag gtcaagcgca tcaccaacag
    50101 ctttttcatg caattgtgga atttcgataa ttccaagctc ttgtgcaatt ccttggttaa
    50161 caagtgcaaa agcgtaagat gaacctacag caccatcacc gacaaggata acttttttgt
    50221 gttgtttagt tgaagtcatt gttttaaaca tctccttaat tttattaggg gattttccct
    50281 agacaacttc attctatcac ttttaaaaaa ctttgtcacg aatatgcctt atagttctcg
    50341 atgtaaacgt tttagtggtt tagaggctga aatagatggg aatttatggt ataatgttgt
    50401 tacttactaa ttgtgaaatg aggcatttat taatgcagga taaaaattta gtgaatgtca
    50461 atctgacaaa ggagatgaag gcaagtttta tcgactacgc catgagtgtt atcgtagcgc
    50521 gagctcttcc tgatgttcga gatggcttaa aacctgttca ccgtcgcatt ctctacggaa
    50581 tgaatgaatt gggtgtgacc ccagacaaac cccataaaaa atctgctcgt attacagggg
    50641 atgtcatggg taaatatcac ccacacgggg attcctctat ttatgaagcc atggtccgta
    50701 tggctcaatg gtggagctac cgttacatgc ttgtagatgg tcatgggaat tttggttcca
    50761 tggatggaga tagtgctgcc gctcaacgtt ataccgaggc acgtatgagc aagattgctc
    50821 tggaaatgct tcgtgatatc aacaaaaata cagttgattt cgttgataac tatgatgcca
    50881 atgaacggga acccttggtc ttgccagcgc gttttccaaa ccttttggtt aatggagcaa
    50941 ctggtatcgc ggttgggatg gcaaccaata ttccacctca taatctgggt gaaaccattg
    51001 atgcagtgaa gttggtcatg gataatcctg aagtgactac caaggacttg atggaagtct
    51061 tgcctggacc agattttcca actggtgctc ttgtcatggg gaaatcaggt atccataagg
    51121 cttatgaaac aggtaaaggt tcgattgtcc tacgttctcg tacagagatt gaaacgacta
    51181 agactggtcg tgagcgtatc gttgtaacag aatttcctta catggtcaat aaaaccaagg
    51241 tgcatgagca tattgttcgc ttggttcagg aaaaacgcat tgagggtatc acagcagtac
    51301 gtgatgagtc aaaccgtgaa ggtgttcgat ttgttattga agtcaagcgc gacgcctcag
    51361 ccaatgttat tctcaataac ctcttcaaaa tgacccaaat gcaaaccaat tttggattca
    51421 atatgctcgc tatccaaaat ggtataccga aaattttgtc tcttcgtcag attttggatg
    51481 cttatattga gcaccaaaaa gaagtggttg ttcgtcgtac acgttttgat aaggaaaaag
    51541 cggaagcgcg cgctcatatc ttagaaggtc tcttgattgc gctagaccat atcgacgaag
    51601 tgattcgtat catccgtgct agtgaaacgg atgcggaagc tcaagctgag ttgatgagca
    51661 agtttaagct ttctgaacgt caaagtcaag ctatccttga tatgcgtctt cgtcgtttga
    51721 caggtttgga acgcgataag attcaatctg agtatgatga cctcttggct ctgattgcgg
    51781 atttagcaga tattcttgct aagcctgaac gtgtttctca aattatcaaa gacgaattgg
    51841 atgaagttaa acgtaaattt tctgataaac gccgtacaga gttgatggtt ggacagatct
    51901 tgagtctcga ggatgaggac ttgattgaag aatcggatgt cttgattacc ctttctaaca
    51961 gaggctacat taagcgtttg gatcaggacg agttcactgc tcaaaaacgt gggggtcgtg
    52021 gtgtccaagg aacgggagtg aaagatgatg actttgttcg tgagttagtg tcaactagca
    52081 cccatgatca tctgctcttc ttcacaaaca agggacgtgt ctatcgtctt aaaggttatg
    52141 aaattcctga gtatggtcgg actgccaaag ggctaccagt agtcaatctc ttgaaattgg
    52201 atgaagatga aagtattcag acggttatca atgttgagtc tgatcgcagt gatgatgctt
    52261 atctcttctt tacaacccgt cacggtattg tgaagagaac tagtgttaag gagtttgcca
    52321 atattcgtca aaatggtctc aaagcgctga atttaaagga tgaagatgag ttaatcaatg
    52381 tcttgttgac agaaggagat atggatatta tcattggtac caagtttggt tatgcagttc
    52441 gctttaatca atcagccgtt cgtggtatga gccgtatcgc cactggtgtg aaaggtgtta
    52501 accttcgtga aggagacaca gttgttggtg ccagcttgat tactgatcaa gatgaggttc
    52561 ttattatcac agaaaaagga tatggtaagc gtacagtcgc tactgaatac ccaacaaaag
    52621 gtcgtggtgg taagggaatg cagacagcta aaattaccga aaaaaatggc ttgctggccg
    52681 gtcttatgac tgttcaaggg gatgaggatt tgatgattat cactgataca ggtgtcatga
    52741 ttcgaaccaa tcttgccaat atttcacaaa caggacgtgc aactatggga gttaaagtaa
    52801 tgcgcctgga tcaagatgct cagatagtga ctttcacaac ggttgcggtg gcagaaaaag
    52861 aagaagttgg gacagaaaac gaaacagaag gtgaagcata atgtctcaaa aaaataataa
    52921 aaagaaaaac aagcgaaaaa atctgctgac aaatatccta gcaggatttc tgatattact
    52981 gtcactggct ttgattttta atactcaaat tcgaaatatt ttcatagtct ggaataccaa
    53041 taagtatcaa gttagccagg tatcaaaaga aaaattagaa gaaaatcagg atacagaagg
    53101 caattttgac tttgattctg tcaaagctat ctcttcggaa gctgttctaa cttctcaatg
    53161 ggatgctcaa aaattaccag ttattggggg aattgcaatt cctgaattgg aaatgaattt
    53221 gccgattttt aaaggacttg ataatgttaa tctcttctac ggagctggta caatgaaacg
    53281 cgagcaagta atgggagaag gaaattatag tctagctagt caccatatct ttggtgttga
    53341 taatgctaat aaaatgttat tttctccttt agataatgct aaaaatggca tgaagattta
    53401 tctaaccgat aaaaataaag tttatactta tgaaatacgt gaagtcaaac gtgtgacacc
    53461 ggatcgtgtt gatgaagttg atgatagaga tggggtcaat gaaatcacat tagtaacctg
    53521 tgaagacctt gctgctacag aacgtattat tgtcaaaggt gatttgaaag aaacaaaaga
    53581 ttattcacaa acatctgatg aaattctaac agctttcaat c
//
LOCUS       DAVKXA010000008        48607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKXA010000008 DAVKXA010000000
VERSION     DAVKXA010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.008"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            122..330
                     /locus_tag="VW883_000510"
                     /pseudo
     CDS             122..330
                     /locus_tag="VW883_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            486..824
                     /locus_tag="VW883_000511"
     CDS             486..824
                     /locus_tag="VW883_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV0273699.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            1014..2450
                     /locus_tag="VW883_000512"
     CDS             1014..2450
                     /locus_tag="VW883_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0273700.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2502..2741
                     /locus_tag="VW883_000513"
     CDS             2502..2741
                     /locus_tag="VW883_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV0273701.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2871..3185
                     /locus_tag="VW883_000514"
     CDS             2871..3185
                     /locus_tag="VW883_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV0273702.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3303..5282
                     /locus_tag="VW883_000515"
     CDS             3303..5282
                     /locus_tag="VW883_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0273703.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5292..5606
                     /locus_tag="VW883_000516"
     CDS             5292..5606
                     /locus_tag="VW883_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV0273704.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5637..6143
                     /locus_tag="VW883_000517"
     CDS             5637..6143
                     /locus_tag="VW883_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273705.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKVYQQFVQ
                     LEKNSLSL"
     gene            6223..7569
                     /gene="celB"
                     /locus_tag="VW883_000518"
     CDS             6223..7569
                     /gene="celB"
                     /locus_tag="VW883_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV0273706.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFRSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7948..8124
                     /locus_tag="VW883_000519"
     CDS             7948..8124
                     /locus_tag="VW883_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273707.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8526..10739
                     /locus_tag="VW883_000520"
     CDS             8526..10739
                     /locus_tag="VW883_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HEV0273708.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNMSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10961..11437)
                     /locus_tag="VW883_000521"
     CDS             complement(10961..11437)
                     /locus_tag="VW883_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0273709.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11660..14863
                     /locus_tag="VW883_000522"
     CDS             11660..14863
                     /locus_tag="VW883_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0273710.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            15243..15619
                     /gene="tnpA"
                     /locus_tag="VW883_000523"
                     /pseudo
     CDS             15243..15619
                     /gene="tnpA"
                     /locus_tag="VW883_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(16006..16635)
                     /locus_tag="VW883_000524"
     CDS             complement(16006..16635)
                     /locus_tag="VW883_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0273711.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNKKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAIKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16645..17646)
                     /locus_tag="VW883_000525"
     CDS             complement(16645..17646)
                     /locus_tag="VW883_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0273712.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17677..18318)
                     /locus_tag="VW883_000526"
     CDS             complement(17677..18318)
                     /locus_tag="VW883_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0273713.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18337..19152)
                     /locus_tag="VW883_000527"
     CDS             complement(18337..19152)
                     /locus_tag="VW883_000527"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0273714.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLIGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19422..19856
                     /locus_tag="VW883_000528"
     CDS             19422..19856
                     /locus_tag="VW883_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0273715.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            19868..21058
                     /locus_tag="VW883_000529"
     CDS             19868..21058
                     /locus_tag="VW883_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0273716.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            21069..21560
                     /locus_tag="VW883_000530"
     CDS             21069..21560
                     /locus_tag="VW883_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0273717.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21575..22354
                     /locus_tag="VW883_000531"
     CDS             21575..22354
                     /locus_tag="VW883_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0273718.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            22341..23159
                     /locus_tag="VW883_000532"
     CDS             22341..23159
                     /locus_tag="VW883_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0273719.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGENQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            23159..23452
                     /locus_tag="VW883_000533"
     CDS             23159..23452
                     /locus_tag="VW883_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0273720.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23474..25375
                     /locus_tag="VW883_000534"
     CDS             23474..25375
                     /locus_tag="VW883_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0273721.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLFLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFMSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSENIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25435..26436
                     /locus_tag="VW883_000535"
     CDS             25435..26436
                     /locus_tag="VW883_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0273722.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26546..26881)
                     /locus_tag="VW883_000536"
     CDS             complement(26546..26881)
                     /locus_tag="VW883_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273723.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26892..27134)
                     /locus_tag="VW883_000537"
     CDS             complement(26892..27134)
                     /locus_tag="VW883_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273724.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(27145..27687)
                     /locus_tag="VW883_000538"
     CDS             complement(27145..27687)
                     /locus_tag="VW883_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0273725.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(27703..27897)
                     /locus_tag="VW883_000539"
     CDS             complement(27703..27897)
                     /locus_tag="VW883_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273726.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEDDF"
     gene            28063..29013
                     /gene="rsmH"
                     /locus_tag="VW883_000540"
     CDS             28063..29013
                     /gene="rsmH"
                     /locus_tag="VW883_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0273727.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            29025..29342
                     /gene="ftsL"
                     /locus_tag="VW883_000541"
     CDS             29025..29342
                     /gene="ftsL"
                     /locus_tag="VW883_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0273728.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            29346..31598
                     /gene="pbpX"
                     /locus_tag="VW883_000542"
     CDS             29346..31598
                     /gene="pbpX"
                     /locus_tag="VW883_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0273729.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            31600..32580
                     /locus_tag="VW883_000543"
     CDS             31600..32580
                     /locus_tag="VW883_000543"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0273730.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            33189..35294
                     /locus_tag="VW883_000544"
     CDS             33189..35294
                     /locus_tag="VW883_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0273731.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMIG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(35591..36073)
                     /locus_tag="VW883_000545"
     CDS             complement(35591..36073)
                     /locus_tag="VW883_000545"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0273732.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(36168..37652)
                     /locus_tag="VW883_000546"
     CDS             complement(36168..37652)
                     /locus_tag="VW883_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0273733.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNRIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTILDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLDINVTFDPYYQYDRLYRK"
     gene            37805..39415
                     /locus_tag="VW883_000547"
     CDS             37805..39415
                     /locus_tag="VW883_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0273734.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNEDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANSDSIFYTYQKL
                     IQIRKENSWLIRADFKLLDTADKVFAYIRKDGDRRFLVVANLSNDKQNFSVDGKVRSV
                     LIENTAAKEVLEKQVLTPWDAFCVEMTD"
     gene            complement(39493..40327)
                     /locus_tag="VW883_000548"
                     /pseudo
     CDS             complement(39493..40327)
                     /locus_tag="VW883_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(40275..41660)
                     /locus_tag="VW883_000549"
                     /pseudo
     CDS             complement(40275..41660)
                     /locus_tag="VW883_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            41837..43282
                     /locus_tag="VW883_000550"
     CDS             41837..43282
                     /locus_tag="VW883_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0273735.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYFNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNIDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSMIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            43284..44015
                     /locus_tag="VW883_000551"
     CDS             43284..44015
                     /locus_tag="VW883_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0273736.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLGKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGEPYKFMKKRAQYFLERDLVHVIASDMHNVDSRPPHMAEAYDLVS
                     QKYGETKAQDLFIDNPRKIVMDQLI"
     gene            44024..44716
                     /locus_tag="VW883_000552"
     CDS             44024..44716
                     /locus_tag="VW883_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV0273737.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSIFIV
                     KPEYTSTTRIYVVNRNQENKPGLTNQDLQAGTYLVKDYHEIILSQDVLEKVATNLKLD
                     IPVKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSIREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGAAAVTVITVLLIELFDTRVKRPEEVEDVLQMP
                     LLGVVPDFNKMK"
     gene            44726..45415
                     /locus_tag="VW883_000553"
     CDS             44726..45415
                     /locus_tag="VW883_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV0273738.1"
                     /translation="MPTLEISQAKLELAKKTEEYYNALCTNLQLSGDDLKVFSISSVK
                     AGEGKTTTSTNIAWAFAHAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPIALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIMQKCDASILVTKAGETKRRELQKAKEQLEQTGKSCLGVVLNKFDTSVDKYGFY
                     GSYGSYRKQKK"
     gene            45430..46791
                     /locus_tag="VW883_000554"
     CDS             45430..46791
                     /locus_tag="VW883_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0273739.1"
                     /translation="MNEKLAKSSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYMLNLFIKWYWKRAYPNFKGSKKVFLLTATSHVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATREVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLILCG
                     LVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVVYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            46823..48001
                     /locus_tag="VW883_000555"
     CDS             46823..48001
                     /locus_tag="VW883_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV0273740.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNDAICYNIDVPNIGPARAIAYDIAAVNKAIEIAKKNKDEAPIF
                     YILACRIGPFIARLKKKIQAIGGTLFVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKYA
                     DLLVCDSKNIEKYIQNDYKQYQPKTTYIAYGTDTSPSILKSEDLKIRSWYQEKGLSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSKKDFVLITNVEQNKFYDQLLQETGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWRKDNLHKVIEESEQKTIEEIKEIDILSTEQVEKRFTWDFIVNEYENLFLLGK
                     "
BASE COUNT        15045 a         8171 c        10550 g        14841 t
ORIGIN      
        1 aaaagtttac cttattttta tagtaatgtg aaataagaat aggacaaacc gaggataatc
       61 aaatcgaatt ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta
      121 tattatggat aatgcaagat tccatagaat gggtaagtta gaactcttgt gtgaagagtt
      181 tgggtataaa ctttaacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac
      241 atgggctcat atcaaaaagc acctcaaaaa ggtattacaa gttgcaatac cttttatgag
      301 gctcttttgt cttgttcttg tttcaattga ctataaatcg ctataagaaa aaatcatttt
      361 attggtataa agaagtgatt gaaagtaatg gcaaaacgtt agataattag ttcataaaaa
      421 acaagtttag atcctcatct aaacttgttt ttttaaaatt gaaggatgat tttggaggat
      481 ataagatgac attgactatt catgtatatt ataaaggtga tggagatagt gcaataaagt
      541 ttgcaagaga aatgcttgat agtggccttg ttgaagaaat tagaaatcaa aaaggtaact
      601 tgaaatacga atatttttta ccaattgaaa aagagggaac tattctcctt attgatcagt
      661 ggataaatca agaaacttta gataaacatt atcaatcaaa gacaatgcag aaaatcttag
      721 atttaagaaa aaaatatcac ttgcagatgc aagttgaacg ttatatagaa gatgattctg
      781 ggatgccaga aagcgataag tcgtttatag acacagggaa ttagaattat tgtgagagtt
      841 tttgtagttt gaaagtattg aaaatcgtaa agatatcatt acgagaatac aagaagatat
      901 tgttctattt ccattaaaaa ttacttcttt ccttaacaat aaggaaaaag aatacgtttt
      961 cattttttgg tttgaggttt ataataagag tatcaaagtc aggaggaaaa aagatgacta
     1021 cttttaaaga tagattttta tggggtggtg ctgttgctgc tcatcaactt gaaggcggat
     1081 ggcaagaagg tggcaaagga attagtgttg ctgatgttat gactgctggt cgtcatggag
     1141 tagctcgtga aattacttcg ggagttttag agggtaaata ttatccaaat catgaggcga
     1201 tagattttta tcatcgttat aaagaagaca tagcactttt tgctgaaatg ggattcaagt
     1261 gcttccgtac ctctattgca tggacacgta tctttccaaa aggtgatgag ttagagccga
     1321 atgaagaagg attacagttt tatgataatc tttttgatga atgcttaaag aatggtattg
     1381 aacctgtcat cactctatct cattttgaaa tgccttatca cttagtgacc gaatatggtg
     1441 gttggaaaaa taggaaattg attgatttct ttgctcgttt tgcagaagtc gtatttaaac
     1501 gttacaaaga taaggttaaa tattggatga ctttcaatga aatcaataat caagcgaatt
     1561 atcaggaaga ttttgcacca tttactaact caggtattgt atatgaggaa ggtgataata
     1621 gagaagcaat tatgtatcaa gcagcacatt acgaactagt tgcttctgca cgagctgtaa
     1681 aaattggtca tgagattaat ccagattttc aaataggttg tatgattgcg atgtgtccaa
     1741 tttatccagc tacttgcaat cctaaggata tcttaatggc aatgaaagct atgcagaagc
     1801 gttattattt tgctgatgtg catgttttag gtaaatatcc tgagcatatt ttcaagtatt
     1861 gggaacgaaa aggtatttca gttgatttta ctgaccagga taaagaagat ttacttggtg
     1921 ggactgtaga ttacattggt ttcagttact atatgtcctt tgctatagac tctcatcgtg
     1981 aaaataatcc ttattttgat tatcttgaaa cagaagattt agtgaaaaat aattatgtta
     2041 aggcttctga atgggagtgg caaattgatc cagaaggttt acgttatgcg ttaaattggt
     2101 ttacagacca ctatcactta ccactcttta ttgttgaaaa tggttttgga gctatagatc
     2161 aagttgcagc agatggtatg gtacatgatg attatagaat tgaatatcta ggtgcccata
     2221 ttcgtgaaat gaaaaaggct gtagttgaag atggtgttga tttaatgggt tatactccat
     2281 ggggatgtat tgatttggtt tcagctggta ccggtgaaat gcggaaacgt tatggcttta
     2341 tttatgtaga taaagatgac aatgggaagg gaagttataa tcgttccccg aaaaaatctt
     2401 ttggctggta taaggaagtt atttcatcta acggtgaatc agtagaatag tataaacaaa
     2461 ctgagattat tctcagtttg tttagcatat tgaggtgaca tatgattgga agtattgcag
     2521 caattttaac aacatttgca tttttaccac aagtttttcg tgtagttaag acaaaggaca
     2581 caggatctat tgctctaggt atgtatgtta tgcaggttat tggtattgca ttgtggcttg
     2641 ctcatggtat tcgtatagga gacttgcctt tgattttagc aaatagtgtt tcatttctac
     2701 tctcaggaat aattttattt tataaattga agtataaata atttttttcc atatcattta
     2761 ggaaaatgag ggaattgtca ttggaaacgc tttattttat aataaaaata gataacaaat
     2821 aagccaactt agcacagctt tgattggatt taagaaaagg agaaaatatt atggcaaaag
     2881 ctttaattat ttgtgcagca ggaatgtctt catcacttat ggcacagaaa acaacagagt
     2941 ttctaaaagg aaaagggaaa gatattgtag ttgatgctat tagtgctact gaaggaggga
     3001 aagctatcgc agcagcagct tttgatttgt atcttgtcag ccctcaaaca aaaatgtact
     3061 ttaagcaatt tgaagaggct ggttctaaag caggaaaacc agttgtacaa atacctcctc
     3121 aagcatatat tcctattcca atgggaattg aaaaaatggc taatttgatt cttgagaata
     3181 tttgatgaac acatgaaatg tcaataaata tttaggttaa gataaattgt tttgagtttg
     3241 atataaactg atttaagtgt ataatatgct tcaatatatg aaaacatacg ttttaggagg
     3301 gaatgaatgt gttaaacatt aaagagaaag atatccttca atttttaata aaaaataagg
     3361 aacgttttgt tacaagcaaa gaactggcag aatatttatc ctgttcagat agaactgtcc
     3421 gtaatgtact gaaattaatt gagaagacaa tgattattca aggagtccgg ttgatttcaa
     3481 aacaaggtca agggtatcaa atattttttg agaatcaagg cgcttaccag gagtttagac
     3541 aaacttatga actggaagaa gactatacga aaactgcggt ttcaaaaggt gatgatcgtt
     3601 tagtatttat cttaaataaa ttattatttg agcaagttcc agttcttttt gatgatttag
     3661 ctgatgaact ttacgttagt cgttcaacat tatctcatga tttcagaaag atacgagtga
     3721 tgttatcaga gtataatttg tccattgaga gtagggcgaa taaaggagtt tatgtctcag
     3781 gcgaggaacg tgataaacga cgttttatca taaattattt cctagagaat caatttttta
     3841 aaacaataca ttgctatgta aaatttaact tttttgatca aactgttcca ttagaagaat
     3901 ttgctagaat tgttttggat gaatgccaag aggccaacct aaaactatct gattttgtac
     3961 tacagaattt agtagttcac atagcattgt ctgtgattcg tttaaaatcc ggatttgaaa
     4021 taaaaaatat agactgtcag atgactgatg atgcaataga gagaaaggtt gcccaaagaa
     4081 ttctttctaa agtaagagaa gtaacaaatc aggaatttcc agttcaggaa atagactaca
     4141 ttactttgca tttgttagct aagagtcaac aatgtcaaaa aaatcagaag aatatttctg
     4201 aagaagtttt aaaaaaatct ttatttaaaa catttcagaa tttaggatta gatgatatgt
     4261 ataacttttc ttcagatttc caactaattg aaggattgat aactcatcta atgacactac
     4321 aagtacgttt agaaagccgg attaccttaa ataacccttt ggtagatgaa attaaacaga
     4381 attatagtga tatattcttt atgactagag aaattcttgc aaatatggac aagttcttgg
     4441 agtggacaat atcagatgat gaagtagcat atgtaagtct tcacttttta gctgctatgg
     4501 aacgtagcaa agagagtact aagtttaata ttcttgctat ttgtgcaaca ggatttggtg
     4561 cagcccaaat gttaagaaat cgtttggaaa cggagtttgg gaagcgagta gaagttgttg
     4621 atgtaatagg ctattatgaa ttgaatcaag aaaaacttaa aggaatagat tttatagtgt
     4681 cagctgttga tttatcaaat ctatattttc aaatcccagt ttttaaagtt agtgtgtttc
     4741 ttaagagtga tgagatggaa atgattagaa aagctatgga tcagatgcaa gtttctagtt
     4801 atgtacaatc atcaaagatt aacaaatttg aaaacaacgg ctttagacag tattttagta
     4861 aagaaaattt tttaatatgt actgaatcag acaaggtaaa tttacttgaa aagatggttg
     4921 agggtttatc tgttggtgaa tcaaatgagt ttgaacaatc tttactttat ggaattaaac
     4981 agcgcgaaga attaagttca gttgtttttt ctgaaaaaat tgcagttccg catcctattc
     5041 agccctttgg tacagaggga aaggtttcgg ttgcaatctg taaagattcg ttactctggg
     5101 ataatcaaag ttcacatgtc cagctagtat ttcttctatc tccatcaata tatgggaacg
     5161 aaggtttggc aactgtgact aaaaagatag tctctctgac agagaatgat gaattgcaaa
     5221 atcagctaat atcttgcaat aactttgaag attttattaa catatttgag aagataaaat
     5281 aggaggttca tatgaatcaa gaggaactgc aggttgcagc atttgaaatt atcctgcatt
     5341 cgggaaatgc aaggtcagaa atacatgaag catttgcaaa aatgagagaa ggtagttttg
     5401 atgatgcaga aagtaaatta aatcaatcaa atgagataat tcttgaagcg catcatgcac
     5461 aaaccaaact cttgcaagaa tacgcaagtg gagtggaaat taaaattgaa attatcatgg
     5521 tacatgctca agatcattta atgaccacta tgacattatt agaagtagca aaggaaatgt
     5581 tagctcttta taagaaagtt aactaaatat gtgttgttat ataaggagga aatgatatgg
     5641 ataaaaaaga acgacaaaaa attgaacaac aacgtcgaga gatggctcta actaatactt
     5701 tttttaatcg atatcttctt ctacgttatt caatagcact cttctttttt gggaatattt
     5761 attggctttt gaatcagttt attaatccct cgcctattat tattttcccc attatgctca
     5821 tagtattttc tattttagca actattgaac aatttaaact ttatggaaat aggaaagaaa
     5881 agttgggaat aacactaatg tttgttagaa tacaaatgct tatttcaata ggattacttg
     5941 ttttaacttg gacaagttgg tttaagaatc tttttccgat ttttgaaaat aaccaagtag
     6001 cacgtttatt tgtttttgta gttcttctat taggtttagt tctgagtttg ttagacatta
     6061 gaagaattaa aaaaatttat aaacgaacag ataaggttta tcaacaattt gtccaattgg
     6121 aaaagaactc acttagttta taatcctgat ctagtataat ttgtatttga aactagtctt
     6181 tagaaagtaa aaattattat gttttattaa ggaggtctat ttatggatca acaaaacggg
     6241 ttgtttggtt ttcttgaaaa ccatgttatg ggaccaatgg gcaaacttgc tcagtttaaa
     6301 gtagtacgtg ctatcacggc tgcaggtatg gctgctgtac catttactat tgtaggatca
     6361 atgtttttgg tattcagtat tttgccacaa gctttctcat tttggccaat tgtggcagat
     6421 attttctctg cttcatttga taaattcaga tcactttaca tggttgcaaa ctatgcgact
     6481 atgggttctc tatctcttta tttcgttcta tcacttgcat atgaattgac aaaaatttat
     6541 gcagaggaag aagaactcaa tatgaatcct cttaatggtg ccttgcttgc cttgatggct
     6601 tttgtcatga cagtaccgca aatcattttt gatggtggaa tgatgaagac tgtgacaagt
     6661 ctaaaagaag gtgcagtaat tgcagatgga tgggcaatgg gaaatggagt cgcacgtttt
     6721 gggacaacag ggatttttac cgcaatcatt atggcaattg tgactgttct tatttatcgt
     6781 atgtgtgtta aacataattg ggttattaaa atgcctgaag ctgttccaga aggagtttct
     6841 cgtggattta ccgctttggt tccgggattt gttgttgcat ttgttgttat ctttatcaac
     6901 ggtcttcttg tagcaatggg aacagatatt tttaaagtca ttgcaattcc atttggtttt
     6961 gtatccaatc tgactaattc gtggattggt ttaatgatta tttatctatt gactcaacta
     7021 ctttggattg taggtatcca cggtgcgaac attgtttttg catttgttag tccaattgct
     7081 cttgccaaca tggctgaaaa tgctgctggc gggcacttcg ctgttgcagg tgaattttct
     7141 aatatgtttg taattgcagg tggttctggt gcaactttag gactatgttt atatattgct
     7201 tttgcctcta aatctgaaca gcttaaagca ataggacgag catctgtagt tccagcctta
     7261 tttaatatta atgaaccatt aatttttgga ttacctatta tctataatcc agccttggct
     7321 ataccattta ttttagcacc aatggttact gctactattt attacgtagc gaattctcta
     7381 aactttatta agccaattat cgcacaggtt ccatggccaa ctccagtagg gattggagct
     7441 ttcttaggga cagcagatct tcgagctgta ttagttgctc tagtatgtgc atttgcagca
     7501 ttcctagtct atcttccatt catccgtgta tatgatcaaa aattggtgaa agaagagcaa
     7561 ggtatctaat aagtaaaaaa gtatactcga tgatagaatc catatagttt aaataatgag
     7621 cgttaacatt agcagtgaag aggtcttttt aagatattct tctctgtttt ttcatatttt
     7681 ttcgctatgt agggtatgaa gcaaaataga aagtagttcg aatagttgat aaacagggaa
     7741 ctgctgttat ttaaaaaaac aataaagtaa agtatgttat cgtagaatac gatacaatag
     7801 taaaaaagca aaaagaatgc gttttatatt tgggtttgag gtttataaaa taggataagc
     7861 gtgctgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca gagaaacatg
     7921 gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga aaagatgaca
     7981 atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta tgctttaagt
     8041 acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt acgagatgaa
     8101 gctcttgctc tggggatgac ttaatgaagc gcaactgtta cgagtcttat gactatgttg
     8161 atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag caggaaggaa
     8221 aaaagcacgt gagcttgaat atcgtatgat tgctagtaag agtttgaaat tatttatcaa
     8281 tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag cttagaaaag
     8341 ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt tgtccactac
     8401 atttttttca attgactatt atttgtcata gatataacag atagaacatt gcattcagaa
     8461 taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa aaggaggaaa
     8521 acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca gacaagctag
     8581 taaggttaga atactctcaa actggaagtt ttgaggatag aacgacacaa cttatctata
     8641 atagagattt tggccaaatt tcgttagatt atatcgagac atcaaacgta ctagatatta
     8701 tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa aatttattta
     8761 tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt gaatctattg
     8821 aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc tcgttagaag
     8881 atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga tttatttggg
     8941 atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc tttgcctatg
     9001 ggcatgatta tagaggagca atcagagact tttaccattt gactggttca acacccttgt
     9061 tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg tcggatgaat
     9121 acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc ggtgtgttag
     9181 atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg acaggatata
     9241 gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt catgatagaa
     9301 agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat gaagaagctt
     9361 atcctcaaat cgcaaaacga ttggggttaa atgtagaact agaagaacct gctatttttg
     9421 atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat gagctagaaa
     9481 agcagggagt agatttttgg tggattgact ggcaacaggg gacacaaggc atgctagatc
     9541 cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca gaaggtggtt
     9601 tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt ttttcagggg
     9661 atactattat tagttggaat tccttaagat ttcaacccta ttttacagcg acagcatcta
     9721 atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg gattatgacg
     9781 aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact cgattacata
     9841 gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca acatctaaga
     9901 ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat accatgaatg
     9961 tacagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc tatccagaga
    10021 atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg atggtggctc
    10081 ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta tggttccctg
    10141 aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg aagttaagtg
    10201 tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc attcccttgg
    10261 ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg tatgtattcc
    10321 cagggaaaca acattttttt gaaatgcttg aagatcaaaa tggtcaaaga tataaaacaa
    10381 gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga gattctagta
    10441 tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatatg tctataattg
    10501 aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa aggacatctt
    10561 taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa ttaaaagata
    10621 gattgttaaa tcaattcatc aatgcgaaaa actctcatga cttaatgaat atcttgcatc
    10681 atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc caaaactaat
    10741 tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg tattcgttat
    10801 cactggtcac attgaaaatg tgaaataagc acctacaaca tagactttac aacacttcat
    10861 gtttcatatc atggggtgtt tttctattta agtcaaagcc catcaaaaaa tctcactatt
    10921 catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga gtttgtatcg
    10981 cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact tgcccatcac
    11041 gaccaatgag aaacttagcg aaattccatt cgattcgttt tcctagtggg ccagatttat
    11101 ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta atcttggcaa
    11161 aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc tctgcgctgc
    11221 cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag ccctgatctt
    11281 gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca catccagtag
    11341 cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt gcttggttgt
    11401 tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt ctttttctac
    11461 attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg aagaataagc
    11521 cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt taactaaacc
    11581 ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga ttttacaata
    11641 tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga gtttgtcttc
    11701 acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg aagaaacgac
    11761 tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg atacaaaaaa
    11821 tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt ggacaggaag
    11881 caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag atgcctcaac
    11941 tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga aattaagggc
    12001 agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc gtttcaagat
    12061 taaaacagat aataaaatcg ggattgccaa agttcgtatc attgaggaaa gtggtaagga
    12121 caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga ccattgaagc
    12181 agactatagc ccgactttag atgttgataa aatcaagctg gagttattct atgaaacagg
    12241 aactgggact gtttccttta aggatattga gctggtagag gtagcagccc agctttctga
    12301 ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg gaaaaaaaca
    12361 tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg cttcagtcaa
    12421 aaatggaatt ttagaacctc ttaaggaagg gacaaccaat gtcattgtca gtaaagatgg
    12481 caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata catacacaga
    12541 ccgtttggat gactggaatg gcatcatcgc tgggaatcaa tactatgatt ctaaaaatga
    12601 acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc tatccagtat
    12661 ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata aaacgtctgc
    12721 aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga ccaatccttc
    12781 ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca tggaatggat
    12841 gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg attatgaaat
    12901 cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact tctctgatga
    12961 ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg aacatttccg
    13021 aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata tgggaagagt
    13081 aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta ccattcgctc
    13141 gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag atggatccta
    13201 tatcgaccat accaatgttg cctatacggg tgcttatggg aatgttttga ttgatggcct
    13261 gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag ataaaatgca
    13321 aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg gagagctgat
    13381 ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg tggccgcagt
    13441 agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa ccaaacaacg
    13501 tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg tctttaagaa
    13561 tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg caggagtcgc
    13621 aagtgttcca agaacaagtt acctatctgc ctttaacaag atggataaaa cagccatgta
    13681 caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta ccttgaatta
    13741 cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga tgttctatct
    13801 ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta atccatataa
    13861 gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag gtaaagtttt
    13921 accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag caaccatgga
    13981 tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc taaaggataa
    14041 gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg caactacaat
    14101 tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg ataaagaagc
    14161 ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt tagaatcatc
    14221 cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca gtatgagtaa
    14281 ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca aggaagttga
    14341 aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt atggctatat
    14401 gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaagagt tagaaagtag
    14461 cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag gagtttgggg
    14521 cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag ttttgaaacg
    14581 tggagtctat accattcgaa aagaagggga tgaatataag attgcctact ataatcctga
    14641 aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag cagctcagcc
    14701 acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc attcggatca
    14761 aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag ggttcttgct
    14821 acttggggcg ttttatttat tccgtagagg aaagaacaac taatttgttc atcatctaga
    14881 tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat atcttcggat
    14941 ttttctttta aaaaaggata agttgatact tatccttttt acttcattat gtgactatag
    15001 cgttttgaaa ctagaatagg acatcataac tgctaaaaga tttctataaa ttcatttgat
    15061 tttcctaatc aatttattcg tatcctattt cactctacta tattagtccg tctcgcacct
    15121 cacggagcga gacaaaacaa ccacccgcta tgcgggtgcg cgtcgaaggt tataccaaaa
    15181 aaactccaaa cgcgatacaa taaaggtgtt caatccactt gtaaagcgaa aggagaaaaa
    15241 atatggcaca aaaggctcat agtttatctc acacaaagtg gaggtgttct atcacattgt
    15301 gttcacccct aagtatagac gaaaagtcat ctataatcaa tatagaagta gtttaggcga
    15361 aatatttcat cgcttgtgta gttataaagg tgttgaaatg atcgagggtc acttaatgcc
    15421 agaccatgta cacatgttag tcagtattcc actaaggcta agtgtttcga gtttcatggg
    15481 ttatttaaaa ggaaaaagtg cactcatgat gtttgacaaa cacgccaatc tcaagtacaa
    15541 gtttgggaat cggcatttct gggtggaagg ttattatgta agtacagtag agcttaataa
    15601 agccacaatt aagaaatata gtcaagatta aagaaattat ccagtggatg atttcttcat
    15661 gagtatgaaa atttgagaac gagtaaagca tgatatatag taaaatgaaa taagaacaga
    15721 acaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta gaggtgtact
    15781 attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat atgaggatcc
    15841 ctttagggat agtggtaagt aataccaaag tctcttaaag aggcaagtga cgagtcaaga
    15901 gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg taatttgggc
    15961 ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc tgagtgtaac
    16021 atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga gtttattgag
    16081 ttcgccacca attccaacgg cgtctgcacc agcagcgaac cattgaggga tgttgtttag
    16141 accgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga ttgcagagat
    16201 atatgctgga ctgagagcac tacctgggaa gagtttgatg atttcactac cggcttcaag
    16261 tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc tgtagagatt
    16321 gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg ctccggctag
    16381 aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac aaacactctg
    16441 atcgtcctga tacaagtcta caagttcttt gatgatttgt cctgcatact gattggtata
    16501 ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt gtagtccttc
    16561 ttccttttta tttcctcgaa tgacagcgac aattttctgt ttttttagtt caataatcgt
    16621 atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg ccagtaaatt
    16681 ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt tgagagttgc
    16741 gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta gttggtaaag
    16801 ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag tttttagttg
    16861 gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt tgtcttgctc
    16921 atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt ttaaaagtcg
    16981 catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct ctagattttg
    17041 gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg caaacttaga
    17101 aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga gatccattga
    17161 aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg cacggacctc
    17221 ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct gaaagagaga
    17281 atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac gatcgtagaa
    17341 aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga ttcgatcgcc
    17401 aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga gaaaacgatc
    17461 tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca gagcttgcaa
    17521 attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa catgatctcc
    17581 gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca gtaatatttt
    17641 cgtcatccat tagttccttt ctggtttaga atagctttac ttggctaata cttctttcaa
    17701 ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga agtatttgcc
    17761 agatatggtg tctttgagga agtcttggtc gattgtttta aggatggtca tcaaatcatt
    17821 gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag ggattacacg
    17881 ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca tcaatttgag
    17941 ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg cgttaccacc
    18001 attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac agacaacacc
    18061 agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg taacaacaaa
    18121 gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca cataagttaa
    18181 ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt cttttttatc
    18241 tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac tattttcatt
    18301 gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt ttccgatgta
    18361 ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc tggcatcact
    18421 agcgagaaag acagcagggc ctatcaaatc ttcaggattt ccccaacgtg cagcaggtgt
    18481 ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca actcacgaag
    18541 aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt ggatattggc
    18601 tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt tagcagcagc
    18661 ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat tgataatctt
    18721 tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa atggtgcgtt
    18781 taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca ttggaactcg
    18841 gcggataata ccagcgttat taacgaggat gtcaatgaca ccaacctctt gttcgatttg
    18901 cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc catgggcttc
    18961 gatgccaact tcacgataag cttcaatccc tttattgacc agatcttgat tgatatcgtt
    19021 aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc caattccata
    19081 agaagcgccg gtgatgagag caatttttcc ttttaaagaa aactgctcaa ttgagaatga
    19141 tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata accaaattat
    19201 attctagtaa accggttttg tcaataaata aatattttta tttataaaaa gatttatttt
    19261 ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa gataatgaaa
    19321 gcgctaatat ttttaaaaaa aactattgac aagataaaaa taaaggatta caatggggaa
    19381 tataaagtaa accggtaaac ctaaacaaga aaggagaaaa gatgaaaatt gtacttgtag
    19441 ggcatggaca ttttgctaca gggatttata gttctttaca attgattgca ggcaatcaag
    19501 aaaatgtgga ggcaattgac tttgtggaag gaatgtcagc agatgaactc aagcaaaaaa
    19561 tcttacttgc aatttcaaat gaagaagaag ttttaatcct aagtgatctc ttgggaggat
    19621 cgccattcaa ggtttcttct accataatgg gagaaaatcc agccaaaaca atgaatgttc
    19681 tctcgggttt gaacttagcc atgttaatgg aagcagtctt tgctagaatg gctcatagct
    19741 ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg cggagtcgta aatggtaaag
    19801 aattgttttc aacggatgca gaggaagagg aagaagattt cgaatcgggt atttaaaggg
    19861 taaaagaatg ataaaaaagg ttacgattga aaaaataaaa tcgcctgagc gcttcttaga
    19921 agtaccactt ctgacgaaag aagaagtcgg ccaggcaatc gataaggtta ttcggcagtt
    19981 agaactcaac cttgactatt tcaaggaaga tttcccgacg ccagctacct ttgataatgt
    20041 ctatccaatc atggataaca cggaatggac caatggtttc tggacaggag aactgtggtt
    20101 ggcttatgaa tacagtcaac aggatgcatt taaaaacatc gctcataaaa atgttctttc
    20161 ttttctggat cgtgtcaata agagagtaga attggatcac catgatctcg gcttcttgta
    20221 cacaccgtct tgtatggctg aatataagat aaatggagat ggagaggcta gagaagcaac
    20281 cttgaaagct gcagataagt tgattgaacg ctatcaagaa aaaggtggtt ttattcaagc
    20341 ttggggagac ttgggcaaga aagagcatta ccgtttgatt attgactgct tgctcaatat
    20401 ccaactctta ttctttgctt atcaagaaac aggcgatcaa aaatactacg atattgcaga
    20461 aagccatttc tatgcttcag ctaataatgt aatccgtgat gacgcttcgt ccttccacac
    20521 cttctatttt gatcctgaga caggtcaacc ctttaaaggt gtaacgagac aagggtatag
    20581 tgatgattca tgctgggcac gtggtcaatc atggggagtc tatggtattc ctttgactta
    20641 tcgtcactta aaagacgagt cctgctttga cttgtttaag ggtgtgacca attatttctt
    20701 gaatcgtctg ccaaaagatc atgtgtccta ttgggatttg atttttaatg atggtagtga
    20761 tcaatcacga gattcttcag caacagctat cgccgtctgt gggattcatg aaatgctaaa
    20821 acatctccca gaggtggatg ctgacaaaga tatttataaa catgctatgc atgccatgct
    20881 tcgttccttg atcgaacatt atgcaaatga tcaatttacc cctggtggga caagtctcct
    20941 ccacggtgtg tactcatggc attcaggtaa aggagtggat gaaggcaata tctggggtga
    21001 ctactattac ctagaagccc ttatccgttt ctacaaagac tggaacctat attggtagga
    21061 ggagaaatat gacaatgcca aatattatta tgacccgtat cgatgaacgg ttgattcatg
    21121 gacaaggaca actttgggta aaatacctag gttgtaatac ggtcattgtt gccaatgacg
    21181 aagtaagcac ggacaagatg caacaaactc tgatgaaaac agttgtgcca gactcagttg
    21241 ccatgcgttt cttccctttg caaaaggtga ttgatatcat tcacaaggct aatcctgctc
    21301 aaacgatctt tatcgttgta aaggatgtga aggacgcttt aaccttggta gaaggtggtg
    21361 tccctatcaa agaaatcaat attgggaaca ttcacaatgc tactggtaaa gagcaagtga
    21421 cacgctccat cttcctgggt gaagaggaca aggcagccct caaggaatta agccaaactc
    21481 atcaagtaac atttaatacg aaaacaactc caacaggaaa tgatggagct gttcaagtca
    21541 acattatgga ctatatttaa aagaggagat cgttatgtcg attaatgtat ttcaagcgat
    21601 tttaattgga ttatggacag ctttctgttt tagtggaatg ctattaggaa tttacaccaa
    21661 tagatgtatt gttctgtcat ttggtgtcgg aattattcta ggtgatctgc ctactgctct
    21721 tgcaatggga gctattggtg aattggctta tatgggattc ggtgttggtg ctggaggtac
    21781 tgttccacca aacccaatcg gacctggtat ctttggtacc ttgatggcta tcactagtgc
    21841 tggtaaagtc agtccagaag cggctcttgc cctctctact ccgattgctg tggcgattca
    21901 attcttacaa actttcgcct acactgtacg tgctggtgcg cctgaaacgg cgatgaagca
    21961 cttgaaaaac cataatttga agaaattcaa gttcactcta aatgcaacaa tttggttgtt
    22021 tgcctttatt ggatttacct tgggttgctt gggtgccctt tcaatggata ccttgttgaa
    22081 actcgtagac tacattccac cggtattgct tacaggtttg acagttgctg gtaaaatgct
    22141 cccagctatc ggttttgcga tgatcttgtc agtgatggct aagaaagagt tgattccctt
    22201 tgtcttgttg ggatatgttt gtgcagctta tctaaacatc ccaacaattg gtattgcaat
    22261 tgtaggtact atctttgctt tgattgaatt ttataacaag ccaaaaacag cggatcatgt
    22321 ggtagaggag gaagcacacg atgactggat ctaacaaatt aacaaaacgt gattatctta
    22381 aaacgtcttt gcgggcattc ttttgtcaaa atggatttaa ctatagtaac tatcaagggt
    22441 tgggatatgc caatgtgatg tatcctgctt tgaaaaaaca ctatggagag aatcaggaag
    22501 gtttctacca agccttggaa gaaaactgtg aattctataa taccaaccca cacttcctgc
    22561 cttttattac cagcttgcat cttgtaatgt tggaaaatgg ccgtccggca aaagaaacac
    22621 gtagcatcaa gatggccttg atgggaccat tagcaggtat tggggattct ctctctcaat
    22681 tctgtttagc tccattgttc tcaaccatcg cagcttcgtt tgctcaagaa ggcttggttg
    22741 tcggtccaat cttgttcttc cttgcgatga atacgatttt aacagcgatt aaattgtcaa
    22801 ctggtctgta tggatacaaa ctaggaacga ctgtgattga taaactaagc gagcagatgg
    22861 caacgatttc tcgtattgcc aatattattg gtgtaaccgt aattgctggt ttggcagcga
    22921 catctgttaa gattatggta ccgatcacct ttgctgcagg ggaagttaaa gcagacgcta
    22981 aacaaagtat cgtaagtatt cagggaatgc ttgataaggt tgctccagct cttctaccag
    23041 ccctatttac acttttagtt tactacttga tcaaagaaaa gaaatggaca acatataaac
    23101 tcgttatttt aacagttatc atcggaatta tcggaagctg gcttaagatt atagcttaat
    23161 ggatacaaca ttgttttatg gaatagtgat tgtcttggca gtgagtcccc ttttactgtc
    23221 aagctttcat tctattcgtc agcaaaagtt gcttcgcaaa cagatggagc aacgacaaga
    23281 gtatttagct tctttaacat ctggtgatga agtgttgtta ttgtctggaa ttcatggaaa
    23341 aatcatttct atccaagatg acttggtctc cttgcagatt gcaaaaggtg tggtcatcta
    23401 tgtagaaaag gaaagtgtaa tgggaaagac aaaagaactg ctttttaagt agttcttttt
    23461 ctggtaatag ataatgaaag aagaaagaag acaatttttt gaaagaatcg atggaaacca
    23521 atgtcgtgat tatatcttgt cccactgttc aaaagactat gagaaagtca agagttccct
    23581 tgaacgcttg atggacaatc gttttatgtt tgatagtcct tgggatatgg agccttgttc
    23641 aaaaatccat caaatccagc cgatggtatg ggatcaagta tttgaagatg atccagaatg
    23701 ggcttatatg ctcaatcgac aagaatatct cttgcagttt atgatagggt atgtggtaga
    23761 aggagataag gactatattc aaaagtgcaa gttctttcta tttgattgga ttgagcaggt
    23821 gagagaattt tctcctcaat ccttgatgac tagaaccttg gatacgggta ttcgttcctt
    23881 tacttggttg aaactactct tgctcctctt gaaatttgac ttgctagagg agaaagaact
    23941 agagaaaatt ttggtcagtc tagaaaagca gattgacttt atgaaaagcc actatcgcgc
    24001 caagtacacc cttagtaact gggggatttt acaaacaatt ccgatgcttg ctatctatca
    24061 tttcttttca gataagatgg acctagaaga agcttaccat tttgcttcag aggagttgaa
    24121 acagcaaatt gagacacaga ttttaggaga tggaagccag tttgaacagt cgattctcta
    24181 tcatgtagag gtttataaag ccttgctgga tttgtttctc ttgcttccag acttgcaaga
    24241 tagttaccaa gagttgctgg aaaagatggc gacctatatt caaatgatga caggcttaga
    24301 tggacggact ttggcttttg gtgatagcga ttctacagaa acgacagaaa tgttgagcct
    24361 gtctgctgtg gttttgaaca aggaagatct tcttaacggt ctggatgtta aagtcgattt
    24421 gcttagcctc ttgttcctgg ggcgagaaaa ggtcaagcga ctgcaggaat ttgaaaagag
    24481 agcttggcag cctaagttca tgagctttga agactctgga catgtctgca ttaaggatga
    24541 acatcgttat ctatttttca aaaatggtcc gctaggaagt gcccatagcc atagtgacga
    24601 gaatagtttt tgcttacagt atcaaggcca acctattttc atagatgctg ggcgttattc
    24661 ttatcgggag atatatgaac gttatctctt aaagagtgct tggagtcatt cgacctgtat
    24721 tgtagatggg aaagctccgg aaagaatcac gggatcctgg gaatatgaat actatcctca
    24781 ctccctgttt tgtcaccata aagaaaggga gggaatgcat tatattgaag gggcttattg
    24841 gtcagcagaa cctgatttgc cttatcttca caggagaaaa atcctcatgc tagtagagga
    24901 tgtctggctc ttggtggatg acatcaggtg tcaaggtcag catgaggcgt tgactcagtt
    24961 tatccttgac aaggatgtga cctatcaaga tgggaaaatc aatcagttga gactatggag
    25021 tgaagttgat tttgatttgg aagataccat catttctcct aaatacaatg agcttgaaag
    25081 aagtagcaaa ctcaccaagc gccaattctt tgagaatcag atgctggatt ataccatcat
    25141 tgcgcatgag agttttgaaa tcatccgtca ttctgtctac cagacagatg atcgtgaagt
    25201 ggaaaatgct ctggcttttg aagtgaaaaa tgatgaaaca gacaagctga ttctgttatt
    25261 aagcgagaat attggtgtag gtgaaaaatt gtgcctcgtt gacggaacaa aaatgcgtgg
    25321 aaaatgtcta gtatatgata aaataaatga gagaatgatt cgcttgcagt gctagaaata
    25381 ggcattttga atagtgaata tgttataata agtattagta ggaggtgttt tagattggag
    25441 aagaaactga ccataaaaga cattgcggaa atggctcaga cctcgaaaac aaccgtgtca
    25501 ttttacctaa acgggaaata tgaaaaaatg tcccaagaga cacgtgaaaa gattgaaaaa
    25561 gttattcatg aaacaaatta caaaccgagc attgttgcgc gtagcttaaa ctccaaacga
    25621 acaaaattaa tcggtgtttt gatcggtgat attaccaaca gtttctcaaa ccaaattgtt
    25681 aagggaattg aggatatcgc cagccagaat ggctaccagg taatgatagg aaatagtaat
    25741 tacagccaag agagtgagga ccggtatatt gaaagcatgc ttctcttggg agtagacggc
    25801 tttattattc agccgacctc taatttccga aaatattctc gtatcatcga tgagaaaaag
    25861 aagaaaatgg tcttttttga tagtcagctc tatgaacacc ggactagctg ggttaaaacc
    25921 aataactatg atgccgttta tgacatgacc cagtcctgta tcgaaaaagg ttatgagcat
    25981 tttctcttga ttacagcgga tacgagtcgt ttgagtactc ggattgagcg ggcaagtggt
    26041 tttgtggatg ctttaacaga tgctaatatg cgccacgcca gtctaaccat tgaagataag
    26101 catacgaatt tggaacaaat taaggaattt ttacaaaaag aaatcgatcc cgatgaaaaa
    26161 actctggtat ttatccctaa ctgttgggcc ctacctctag tctttaccgt tatcaaagag
    26221 ttgaattata acttgccaca agttgggttg attggttttg acaatacgga gtggacttgc
    26281 ttttcttctc caagtgtttc gacgctggtt cagccctcct ttgaggaagg acaacaggct
    26341 acaaagattt tgattgacca gattgaaggt cgcaatcaag aagaaaggca acaagtcttg
    26401 gattgtagtg tgaattggaa agagtcgact ttctaaaatg aaggaaaatg acttgcaatc
    26461 tctgttaaga aataaaataa tcccacctag aacaagctag gtgggattat ttgcctataa
    26521 aatgagaaat tatgggagca agctcctaaa tcaactgttt ttgatctact tctttaacta
    26581 cttgataaaa gttatagaag taggccaaac ttgaaatgat ggttacgact aggaatattg
    26641 aaaatttcca ttggacaggg ttggttaaaa gttgtggaaa ggatatgagg agaaagaaga
    26701 gggctgcgtt gaggacaggt atccgttttg attgtatttt ctcaagtcct ttattgagcg
    26761 caggaagaaa gaggagtagg agtagtaaaa ctgtatgaga aatagctcct gaagtaaggg
    26821 cgaagaaaag gaaaatactg ataaaaacat gaatgatcag tagtctagct agtgatttca
    26881 taaggcacct cctaatcctg gtctttttta gctcttgcaa tacgaagtga gtcgacaata
    26941 tgtatcatca ctccgaaaaa gaaagctccc agtatagttt taaaaatatg ttttgtattt
    27001 agaagagaac tgataaaatt tggattttca cttgttaggg tatcaatgag tggaattata
    27061 aaaaatatca ctgttccata aatcgaacct gctttcagac caggataacg taactgtttc
    27121 ttttcttttt tcatgagttt cctcctaatc ctcatcttga tttttcttag tttttgcaat
    27181 gcgacgggag atgaggaact gtatgctcgc tccgaagaaa atagaaccga gaatacttga
    27241 tacaccattt cttatagtga gaagagaatg aaaatagtcc tgaccttcat ctatgagtat
    27301 actgagaaga ggagttataa aaaacatcca tagaccaaag aacaaacctg ctttcagacc
    27361 agggtagtgt agttgcttgc tttctttctc attcagcata tctggttcaa tgactgtgat
    27421 gcctgttttt ttcatttggt aggtgacata gccagaagcg atgagggcaa tcactaaaat
    27481 cagaggagga tagattagag ccacttcttg agggtattta taggccagaa ggagtggaat
    27541 aatatttccg aaaatcatca gataaaagag gacgataaag acttggttcc caatactatc
    27601 ggcctcacgc cgtttgtatt cgtcaagggg accagaaata ccgtatgtgc gtttgatcag
    27661 tttttcagtg aaggtttctt ttttcatgag tttgcttctt ttttaaaaat catcctccca
    27721 aaagagactg ttgaggtcag tttggaggct gcgggcgaga ttgagacaga gttccaaggt
    27781 tggattgtac ttgtcgtttt caatcatatt gatagtctgt ctcgagacac cgatatcctt
    27841 ggcgagttcg agctgggaaa tacccaattc cttgcgaaat tctttcacac gattcatctg
    27901 gtctcctttc tgatttatgt cgtatatatt tgactatatt atagtctttt aaacataaag
    27961 tgtcaagtat ttttgacata ttttttgaag aaatagtagt ctccttgtcc tatttgtctg
    28021 acaagtgcaa gctggtcgga tttgtggtaa aatagataag atatgacaaa agaatttcat
    28081 catgtaacgg tcttactcca cgaaacgatt gatatgcttg acgtaaagcc tgacggtatc
    28141 tacgttgatg cgactttggg cggagcaggc catagcgagt atttattaag taaattaagt
    28201 gaaaaaggcc atctctatgc ctttgaccag gatcagaatg ccattgacaa tgcgcaaaaa
    28261 cgcttggcac cttacattga gaagggaatg gtgaccttta tcaaggataa cttccgtcat
    28321 ttacaggcac gtttgcgtga agctggtgtt caggaaattg atggaatttg ttatgacttg
    28381 ggagtgtcta gtcctcaatt ggaccagcgt gagcgtggtt tttcttataa aaaggatgcg
    28441 ccactggaca tgcggatgaa tcaggatgct agtctgacag cctatgaagt ggttaatcat
    28501 tatgactatc atgatttggt tcgtattttc ttcaaatacg gtgaggataa attctctaaa
    28561 cagattgcgc gtaagattga gcaagcgcgt gaagtgaagc cgattgagac aacgactgag
    28621 ttagcagaga ttatcaagtt ggtcaaacct gccaaggaac tcaagaagaa ggggcatcct
    28681 gctaagcaga ttttccaggc tattcgaatt gaagtcaatg atgaactggg agcggcagat
    28741 gagtccatcc agcaggctat ggatatgttg gctctggatg gtagaatttc agtgattacc
    28801 tttcattcct tagaagaccg cttgaccaag caattgttca aggaagcttc aacagttgaa
    28861 gttccaaaag gcttgccttt catcccagat gatctcaagc ccaagatgga attggtgtcc
    28921 cgtaagccaa tcttgccaag tgcggaagag ttagaagcca ataaccgctc gcactcagcc
    28981 aagttgcgcg tggccagaaa aattcacaag taagagggaa aaagatggca gaaaaaatgg
    29041 aaaaaacagg tcaaatacta cagatgcaac ttaaacggtt ttcgcgtgtg gaaaaagctt
    29101 tttacttttc cattgctgta accactctta ttgtagccat tagtattatt tttatgcaga
    29161 ccaagctctt gcaagtgcag aatgatttga caaaaatcaa tgcgcagata gaggaaaaga
    29221 aaaccgaatt ggacgatgcc aagcaagagg tcaatgaact attacgtgca gaacgtttga
    29281 aagaaattgc caattcacac gatttgcaat taaacaatga aaatattaga atagcggagt
    29341 aagatatgaa gtggacaaaa agagtaatcc gttatgcgac caaaaatcgg aaatcgccgg
    29401 ctgaaaacag acgcagagtt ggaaaaagtc tgagtttatt atctgtcttt gtttttgcca
    29461 tttttttagt caattttgcg gtcattattg ggacaggcac tcgctttgga acagatttag
    29521 cgaaggaagc taagaaggtt catcaaacca cccgtacagt tcctgccaaa cgtgggacta
    29581 tttatgaccg aaatggagtc ccgattgctg aggatgcaac ctcctataat gtctatgcgg
    29641 tcattgatga gaactataag tcagcaacgg gtaagattct ttacgtagaa aaaacacaat
    29701 ttaacaaggt tgcagaggtc tttcataagt atctggacat ggaagaatcc tatgtaagag
    29761 agcaactctc gcaacctaat ctcaagcaag tttcctttgg agcaaaggga aatgggatta
    29821 cctatgccaa tatgatgtct atcaaaaaag aattggaagc tgcagaggtc aaggggattg
    29881 attttacaac cagtcccaat cgtagttacc caaatggaca atttgcttct agttttatcg
    29941 gtctagctca gctccatgaa aatgaagatg gaagcaagag cttgctggga acctctggaa
    30001 tggagagttc cttgaacagt attcttgcag ggacagacgg cattattacc tatgaaaagg
    30061 atcgtctggg taatattgta cccggaacag aacaagtttc ccaacgaacg atggacggta
    30121 aggatgttta tacaaccatt tccagccccc tccagtcctt tatggaaacc cagatggatg
    30181 cttttcaaga gaaggtaaaa ggaaagtaca tgacagcgac tttggtcagt gctaaaacag
    30241 gggaaattct ggcaacaacg caacgaccga cctttgatgc agatacaaaa gaaggcatta
    30301 cagaggactt tgtttggcgt gatatccttt accaaagtaa ctatgagcca ggttccacta
    30361 tgaaagtgat gatgttggct gctgctattg ataataatac ctttccagga ggagaagtct
    30421 ttaatagtag tgagttaaaa attgcagatg ccacgattcg agattgggac gttaatgaag
    30481 gattgactgg tggcagaatg atgacttttt ctcaaggttt tgcacactca agtaacgttg
    30541 ggatgaccct ccttgagcaa aagatgggag atgctacctg gcttgattat cttaatcgtt
    30601 ttaaatttgg agttccgacc cgtttcggtt tgacggatga gtatgctggt cagcttcctg
    30661 cggataatat tgtcaacatt gcgcaaagct catttggaca agggatttca gtgacccaga
    30721 cacaaatgat tcgtgccttt acagctattg ctaatgacgg tgtcatgctg gagcctaaat
    30781 ttattagtgc catttatgat ccaaatgatc aaactgctcg gaaatctcaa aaagaaattg
    30841 tgggaaatcc tgtttctaaa gatgcagcta gtctaactcg gactaacatg gttttggtag
    30901 ggacggatcc ggtttatgga accatgtata accacagcac aggcaagcca actgtaactg
    30961 ttcctgggca aaatgtagcc ctcaagtctg gtacggctca gattgctgac gagaaaaatg
    31021 gtggttatct agtcggggta accgactata ttttctcggc tgtatcgatg agtccggctg
    31081 aaaatcctga ttttatcttg tatgtgacgg tccaacaacc tgaacattat tcaggtattc
    31141 agttgggaga atttgccaat cctatcttgg agcgggcttc agctatgaaa gactctctca
    31201 atcttcaaac aacagctaaa gctttggagc aagtaagtca acaaagtcct tatcctatgc
    31261 ctagtgtcaa ggatatttca cctggtgatt tagcagaaga attgcgtcga aatcttgtac
    31321 aacccatcgt tgtgggaaca ggaacgaaga ttaaaaacag ttctgctgaa gaagggaaga
    31381 atcttgcccc gaatcagcaa gtccttatct tatctgataa agcagaggag gttccagata
    31441 tgtatggttg gacaaaggag actgctgaga cccttgctaa gtggctcaat atagaacttg
    31501 aatttcaagg ctcgggctct actgtgcaga agcaagatgt tcgtgctaac acagctatca
    31561 aggacattaa aaaaattaca ttaactttag gagactaata tgtttatttc catcagtgct
    31621 ggaattgtga catttttact aactttagta gaaattccgg cctttatcca attttataga
    31681 aaggcgcaaa ttacaggcca gcagatgcat gaggatgtca aacagcatca ggcaaaagct
    31741 gggactccta caatgggagg tttggttttc ttgattactt ctgttttggt tgctttcttt
    31801 ttcgccctat ttagtagcca attcagcaat aatgtgggaa tgattttgtt catcttggtc
    31861 ttgtatggct tggtcggatt tttagatgac tttctcaagg tctttcgtaa aatcaatgag
    31921 gggcttaatc ctaagcaaaa attagctctt cagcttctag gtggagttat cttctatctt
    31981 ttctatgagc gcggtggcga tatcctgtct gtctttggtt atccagttca tttgggattt
    32041 ttctatattt tcttcgctct tttctggcta gtcggttttt caaacgcagt aaacttgaca
    32101 gacggtgttg acggtttagc tagtatttcc gttgtgatta gtttgtctgc ctatggagtt
    32161 attgcctatg tgcaaggtca gatggatatt cttctagtga ttcttgccat gattggtggt
    32221 ttgctcggtt tcttcatatt taaccataag cctgccaagg tctttatggg tgatgtggga
    32281 agtttggccc taggtgggat gctggcagct atctctatgg ctctccacca agaatggact
    32341 ctcttgatta tcggaattgt gtatgttttt gaaacaactt ctgttatgat gcaagtcagt
    32401 tatttcaaac tgacaggtgg taaacgtatt ttccgtatga cgcctgtaca tcaccatttt
    32461 gagcttgggg gattgtctgg taaaggaaat ccttggagcg agtggaaggt tgacttcttc
    32521 ttttggggag tgggacttct agcaagtctc ctgaccctcg caattttata tttgatgtaa
    32581 gaatggcacc ctgatgtttc agggtgtttt tgtgtttaaa tacacaatga aaatcaaaga
    32641 acaaactaga aagctaactt taggctgctc aaaacatagt agtttgaaac tagaatagta
    32701 cacatctact tctaaaatat tgttagaaat cgatttgact gtcctgatcg acttgtcctg
    32761 ttcttatttc attttactat acagttttga gatggttgat agaactgacg aagtcagctc
    32821 aaaacacggt tttgaggttg tagataagga gaagctgatg tggtttgaag aggttttcga
    32881 agagtgtaaa aaaatattgg tcagttaaag tcaaaactat tgaccttttc tgaccaatgt
    32941 agtatattat gaacgtaagg taaatgaaag ccttactaga acacttattt aaagtaaaat
    33001 agaaagaggt gggtctatgt ttcatctaga aatcttcaga agtaaagatg gtctactcct
    33061 gcttgaaaaa gaaaaaccag aaatagtacg tagggtagcg gtttagctag tctaaatttt
    33121 ttaaaacaaa ggtcaaagat agtcaatatc agtaatcata actaagtaaa caaaaagagg
    33181 taaagaatat gaataacaac tttaataatt ttaataacat ggatgattta tttaaccaat
    33241 tgatgggtgg tatgcgagga tatagttctg aaaatcgccg ttacttaatt aatggacgcg
    33301 aagtcacacc tgaggaattt gctcactatc gtgcgactgg tcaattacca ggaaatgcag
    33361 aaactgatgt gcaaatgcca caacaggcat caggtatgaa acaagacggt gtccttgcaa
    33421 aactaggtcg aaacttaaca gcagaagcgc gtgagggcaa gttggatcct gttatcggac
    33481 gaaacaagga aattcaagaa acatctgaaa tcctctcacg ccgcaccaag aacaatcctg
    33541 ttttggtcgg agatgcaggt gttggtaaga cagcagttgt cgaaggtcta gcgcaagcca
    33601 ttgtgaacgg agatgttcct gctgctatca agaacaagga aattatttct attgatatct
    33661 caggtcttga ggctggtact caataccgtg gtagctttga agaaaatgtc caaaacttag
    33721 tcaatgaagt gaaagaagca gggaatatta tcctcttctt tgatgaaatt caccaaattc
    33781 ttggtgctgg tagcactggt ggagacagtg gttctaaagg gcttgcggat attctcaagc
    33841 cagctctctc tcgtggagaa ttgacagtga ttggggcaac aactcaagac gaataccgta
    33901 acaccatctt gaagaatgct gctcttgctc gtcgtttcaa cgaagtgaag gtcaatgctc
    33961 cttcagcaga gaatactttt aaaattcttc aaggcattcg tgacctctat caacaacacc
    34021 acaatgtcat cttgccagac gaagtcttga aagcagcggt ggattattct gttcaataca
    34081 ttcctcaacg tagcttgcca gataaggcta ttgaccttgt cgatgtaacg gctgctcact
    34141 tggcggctca acatccagta acagatgtgc atgctgttga acgagaaatc gaaacggaaa
    34201 aagacaagca agaaaaagca gttgaagcag aagattttga agcagctcta aactataaaa
    34261 cacgcattgc agaattggaa aggaaaatcg aaaaccacac agaagatatg aaagtgactg
    34321 caagtgtcaa tgatgtggct gaatccgtgg aacgaatgat aggtatccca gtatcgcaaa
    34381 tgggagcttc agatatcgaa cgtttgaaag atatggctca tcgcttgcaa gacaaggtga
    34441 ttggtcaaga taaggccgta gaagctgtag ctcgtgctat ccgtcgtaac cgtgctggtt
    34501 ttgatgaagg aaatcgccca atcggcagct tcctctttgt agggtctact ggggttggta
    34561 agacggagct tgctaagcaa ttggcactcg atatgtttgg aacccaggat gcgattatcc
    34621 gtttggatat gtctgaatac agtgaccgca cagctgtttc taagctaatt ggtacaacag
    34681 caggctatgt gggttatgat gacaatagca ataccttaac agaacgtgtt cgtcgcaatc
    34741 catactctat cattctcttg gatgaaattg aaaaggctga ccctcaagtt attacccttc
    34801 tcctccaagt tctagatgat ggtcgtttga cagatggtca aggaaataca gtaaacttca
    34861 agaacactgt cattattgcg acctcaaatg ctggatttgg ctatgaagcc aacttgacag
    34921 aagatgcgga taaaccagaa ttgatggacc gtttgaaacc cttcttccgt ccagaattcc
    34981 tcaaccgctt taatgcagtc atcgaattct cacacttgac taaggaagac ctttctaaga
    35041 ttgtagattt gatgttggct gaagttaacc aaaccttggc taagaaagac attgacttgg
    35101 tagtcagtca agcggctaaa gattatatca cagaagaagg ttacgacgaa gtcatgggag
    35161 ttcgtcctct ccgtcgagtg gttgaacaag aaattcgtga taaggtgaca gacttccact
    35221 tggatcattt agatgctaaa catctggaag cagatatgga agatggcgtt ttggttattc
    35281 gtgagaaagc ctaagataga attttgagga taaaaaagaa ggagccagct gaaaaaaaac
    35341 tggttccttt tgaggtacga cgggcatgtc gtatagtaga agtgtattat tctagtttca
    35401 atttactata gtagctcaga agtcggtact taaacgtgct atatcaaaac cagtccttga
    35461 aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatgcgt taaaagttag
    35521 ttgaaccgcc gtatgccgaa cggcacgtac ggtggtgtga gaggggctag agattatccc
    35581 ctactcgatt ttaaatcaca tgacgttcaa aggcatcatc tgaaatccct tgttccaaga
    35641 tgagttttgc ccattcttta gcagagaaga ggctgtggtc cttgtagttt ccgcaagatt
    35701 cgatggttgt ccctgggaca tcttcccaag tagtagtttc agcgatttcc ttgagcgaat
    35761 ccttgataac agctgcgatt ttagcactgg tgtgacgtcc ccacataatc atgtggaagc
    35821 ctgtgcggca accaaatggt gaacagtcaa tcatgccgtc aatgcgggta cggatgagtt
    35881 tggctaagag gtgctcgata gtgtgaaggc cggcggtagg gatagagtct tcgtttggtt
    35941 gcaccaagcg aatatcataa ttggagatga tgtctccttt tggtcctgtt tcttccccaa
    36001 tcaagcgaac atagggtgct ttgacaatgg tgtggtcaag ttcaaaactt tcgacaataa
    36061 cttcttttga catggtaaat cctttcagtt ttcttctctc attatatcat aaaggttgct
    36121 cctgagacag agagaaaacc tctccgaggc tggagaggtt gaaatcttta cttacgatat
    36181 aagcggtcgt attggtagta tgggtcaaag gttacgttga tatccagttt acgaaggaca
    36241 ttcttgtctt catcagtcaa gatgatggtt gagtgggctt cgcttccttt gaggttgccg
    36301 agttcttcca tagcgcgggc agcatcagga ttttctgtag ctgtgatagc aagtgcaatc
    36361 aggatttcat ttgaatgaag gcgtggattg cggctaccga gatgatcgat tttaagacct
    36421 tggattggct taacaacttc aggttcgatt agttttactt ctttagcgat gtcagctgat
    36481 tttttgatgg cgttgatcaa ggcagcggct gtaggaccaa agagttctga gttcttacca
    36541 gtgacgattt ccccatttgg caattcaaag gctagggctg gtccaccagt ttcttctgct
    36601 ttttggcgcg caacgacagc aaccttacgg tctgcaggtg tgataccgag gtcgttcatg
    36661 agcaactcaa ttttcttgac ggcagcttcg ccaacttttt cagctttgaa gtcaagaatt
    36721 gtttgatagt aacggcggat gatttcttgt ttagaagctt cgacagcggc ctcgtcatct
    36781 gtaatagcga aaccaaccat gttgacaccc atatctgtcg gtgaagcgta tggtgatttt
    36841 ccgagaatac gttccaacat gcgtttgagc actgggaaga tttcgatatc acggttgtag
    36901 ttgacagtgg tttctccata ggtttgaaga tggaaggggt caatcatgtt gacatcatca
    36961 aggtcagctg tggcagcttc ataagccaag ttaactggat gatgaagggg aagattccaa
    37021 acagggaagg tttcaaattt agcgtagcca gacttgatgc cattgatttg gtcgtggtac
    37081 atattggaca tacacgttgc caattttcca gaaccgggtc caggagcggt tacgacaatc
    37141 aagttgcgac tggttttgat gtagtcgttt ttgcccatgc cttctgggga aatgatgtga
    37201 tccatatccg tcggatatcc tttgattgga taatgaagat aagaatcaat tctgtttttc
    37261 tcaagttggt tgcggaaggc atctgcagcg agttggccag cgtattgtgt aatgacaacg
    37321 gaaccaacaa aaatccctaa ttcattgaat ttgtcaatca aacgaagaac ttcttggtca
    37381 taagaaatgc ctaagtcgcc acgtgctttg gaatgttcaa tgttgctagc attaatggca
    37441 atcacaacct caacttgctc tttcaattct tgcaagagct tgattttgtt gtcaggttca
    37501 taaccaggaa ggacacgagc agcgtggaaa tcttctaaca ttttgccacc aaactctagg
    37561 taaagcttgc cgtcaaattg gttaatgcgc tctaagatgt ggtcgcgttg tagatttaaa
    37621 tattgttcag aactaaaagc ttgttttttc atttttttac ctctggactc tattataata
    37681 aaaaattgga agttaggaaa ctacggagct aaaaaagaaa ttaaaaagat taagcaaacg
    37741 cttgcacaaa attttaaaaa gtgctattat agactataga ttatgaaaat aatgaggtaa
    37801 gaagatgcaa gaaaaatggt ggcataatgc cgtagtctat caagtctatc caaagagttt
    37861 tatggatagt aatgaagatg gaattggcga tttgccagga attaccagta agttggacta
    37921 tctagccaag ctaggaatca cagcaatttg gctttctccc gtttatgaca gccctatgga
    37981 tgataatggc tacgatattg ctgattatca agcgattgcg gctatttttg gaaccatgga
    38041 ggacatggat cagctgattg cagaagctaa gaagcgtgat atccgtatca tcatggactt
    38101 ggtggtcaat catacctcgg atgagcatgc ttggtttgtc gaagcctgtg aaaatactga
    38161 cagccctgag cgagactact atatctggcg cgatgaaccc aatgacctag attctatctt
    38221 tagtgggtct gcttgggaat acgatgaaaa gtcaggtcaa tactatctcc actttttcag
    38281 caagaaacag ccggatctca actgggaaaa tgaaaaactt cgccagaaaa tttatgagat
    38341 gatgaacttc tggattgata aaggtattgg tggtttccgt atggatgtta ttgacatgat
    38401 tggcaaaatt cctgacgaga aggtagtcaa taatggtcct atgctccatc cctatctcaa
    38461 ggaaatgaat caggcgacct ttggagataa ggagctcttg acagtagggg agacttgggg
    38521 agcaacgcca gagattgcca agctctactc tgatccaaag gggcaagaat tgtctatggt
    38581 cttccagttt gaacatatcg gtcttcagta tcaggaaggt cagcctaaat ggcactatca
    38641 aaaagagctg aatattgcta agttaaaaga aatcttcaac aaatggcaga cagagttagg
    38701 agttgaggac ggctggaatt ccctcttctg gaacaaccat gacctccctc gtattgtctc
    38761 aatctgggga aatgaccaag aataccgtga aaaatctgcc aaagcctttg cgattttgct
    38821 tcatctcatg agagggactc cttatatcta ccaaggtgag gagattggga tgaccaacta
    38881 tccgtttgaa acactggatc aagtagaaga tattgaatct ctcaactatg cgcgtgaggc
    38941 tcttgaaaaa ggtgttccga ttgaagaaat catggacagt atccgtgtta ttggacgtga
    39001 caatgcccgt acccctatgc aatgggacga gagcaaaaac gctggtttct caacaggtca
    39061 accttggttg gcggttaatc caaactacga agaaatcaac gttcaagaag cactggcaaa
    39121 ctcagattct attttctata cctatcagaa actcatccag attcgtaagg aaaacagctg
    39181 gttgattcga gctgatttta aattactcga tacggctgat aaggtctttg cttatatccg
    39241 taaggacggt gaccgtcgct tcctagtcgt ggctaattta tccaatgata aacaaaactt
    39301 ttcagtagat ggaaaagtta gatctgtctt gattgaaaac actgcggcta aagaagtact
    39361 tgaaaaacag gtcttgactc catgggatgc tttctgtgtg gaaatgactg actagaatga
    39421 gcaagagcct gggacaaaat agttctcgac cacaaaaaag ctagagattt ccaattgtgg
    39481 aactctagct ttttaatttt gagtcattct cttattgtat tttaggaggt tattggccat
    39541 aagtaccaat cccatgtcaa ttctcacttg acgcttgccc ctcagattac atctcttgta
    39601 acccaaacaa gcctttatct gcccaaagac aggttccaca tcaatcttgc gttgagcgaa
    39661 aatctgtcta ccttggggag ataaaagcgc ctgacattct ttagctttca agttttgata
    39721 gccttcgttc atatacagtc cccttttgag gggctgattc aggttcgtcg acgtagtaaa
    39781 ccttgatttc ttgttgaaag tctgtctgtg ttttctgatg tttggtatgg tgaaaacgat
    39841 aatactagcc atcaggatgt gtatagctat cctccttgtc attatagtgc caattcgcta
    39901 agtttttagc tgactgttta tagcctctct tctgttcctt atcaaacatg gcatatttaa
    39961 tcagatggtt tacctccttt tcatctaaac gaaggaggtt ctcttcactt ccatatccag
    40021 catctgcgac aactgtcttc aagtcatgcg gataggtttc aaggaatggc agaagagtct
    40081 tggtatctgt cggatttgaa aagacatcat agtgaagaac aaattggttt tccgtagcga
    40141 tttgaagatt ataagcagcc ttgggttgac tatttttcat atgttcttcc ttcatccgca
    40201 taaaagtggc atctggatcg gttttggaaa aactgttagg cccttgaaat gtctcctgat
    40261 agttctcata tttttcagca cgtactgaaa aatcctcctt taaactcttc ataatccttt
    40321 ttatttttat gaagatattg tttgaaagat gtgagtttcc acggatgggt ttgtggaggg
    40381 atatacttgc gtctttcttt ttttgttctg gttcttgttc aaggtttttc gaatagagtt
    40441 catgatttag tagctccttt gtgtgataga ttttgtcagc gatattgagg tagatgtcac
    40501 catcaaatgc ttttataact aatgcttttg tctttctgat gaaatagact tcttttcctt
    40561 gctcggtagg gatatagcaa cgattttgga atcggatatg gtgtccacta tcgacgactc
    40621 tctcccgcca gtttagctag aatgagattt cgttcagagg gcttaggagc ctcctcaaag
    40681 acagagagtt ttgtcttgtt tccaaactgt tcattaaagg tttggatata ggaaggcaga
    40741 aaggtattgg cttcttccaa ggtatgaatc ttgtttcgtt ccagttcgat aggcaagaga
    40801 gattgtagta tctgattgag tctttcgact ctccctttag cttgagggat agaggttgtc
    40861 tcaaggagaa ttcccagttg gtgacaggcg tatccaaatt gtgtatgggt gtcgtcctcc
    40921 attttcttag agttggaggc ttgataggta aaaacagttc tcttatctgt tttgatttga
    40981 acaggaatgc cgtggttggc taagatttgt tcgaggacat gatagtaagc attcaaggtc
    41041 tcttgtttgt caaaataagc gcctaggata ttgccagaag catcatcaat ggctaggtgt
    41101 aagttagagg tttctgctcc aaaccaggca tgagggctgg catccatttg gatgagttct
    41161 ccagcaaatt tctttctggg tctactagga tgtacctttt tagggtcttc caggaagttt
    41221 tcagccgtcg gtaagattgg attgtctagg ggttgcttgg ggttcagttt agcttgcttt
    41281 cttactctct tctttgtctt tctatgggac ttaggcgaca ggatattttt cttatagagt
    41341 atttttctaa cagtagtatc agagagctga attccttctt cttcagctag caattcacag
    41401 aaatgacgga catttggttt atatgtttca taggagaggt atttctttag gatacgttct
    41461 ttgatttcat cagggattgc atgttttggt tttcgatttc tgtttccgtg tctgaaggct
    41521 tcttttcctt tctgttgata ggctagtagc agacgattga tttgcctttc agaaagattg
    41581 agctcgacac aggctcgttt ctttgttttc tttccttggg ctatagcttt tatcacaaga
    41641 tattttttcg tttcattcat attcagttgg atcctttaca tatgactatt ctaccaaatg
    41701 ggacattttt acgttcgatt tactaaagac attatcacat tcgaattaca caagatgcag
    41761 atagtgaaaa aaaggtgtag acattaccgt aaaaaagtga tataattgta agatgttcaa
    41821 tgtataggtg ttaatcatga gtagacgttt taaaaaatca ggttcacaga aagtgaagcg
    41881 aagtgttaat atagttttgt tgactattta tttattgtta gtttgttttt tattgttctt
    41941 aatctttaag tacaatatcc ttgcttttag atattttaat ctagtggtaa ctgcgttagt
    42001 cctactagtt gccttggtag ggctactctt gattatctat aaaaaagctg aaaagtttac
    42061 tatttttctg ttggtgttct ctatccttgt cagctctgtg tcgctctttg cagtacagca
    42121 gtttgttgga ctgaccaatc gtttaaatgc gacttctaat tactcagaat attcaatcag
    42181 tgtcgctgtt ttagcagata gtgatatcga aaatgttacg caactgacga gtgtgacagc
    42241 accgactggg actgataatg aaaatattca aaaactacta gctgatatca aatcaagtca
    42301 gaatatcgat ttgacggtca atcaaagttc gtcttacttg gcagcttaca agagtttgat
    42361 tgcaggagag actaaggcca ttgtcttaaa tagtgtcttt gaaaatatca tcgaatcgga
    42421 gtatccagat tacgcatcga agataaaaaa gatttatacc aagggattca ctaaaaaagt
    42481 agaagctcct aagacgtcta agaatcagtc tttcaatatc tatgttagtg gaattgatac
    42541 ttatggtccg attagttcgg tgtcgcgttc agatgtcaat atcctgatga ctgtcaatcg
    42601 agataccaag aaaattctct tgaccacaac gccacgtgat gcttatgtac caatcgcaga
    42661 tggtgggaat aatcaaaaag ataaattgac ccatgcgggc atctatggag ttgattcgtc
    42721 cattcacacc ttagaaaatc tctatggagt ggatatccat tactatgtcc gtttgaactt
    42781 cacttctttc ttgaaattga tcgatttgtt gggtggggta gatgtttata atgaccaaga
    42841 tttcacatct ctacacggga agttccattt cccagttgga aatgtccact tagattctga
    42901 gcaggctctg ggatttgttc gtgagcgcta ttccctagcg gatggtgatc atgaccgcgg
    42961 gcgcaatcaa caaaaggtga ttgcggctat ccttcaaaaa ttaacttcga gcgaagcgct
    43021 gaaaaattat agtatgatca ttgatagctt gcaagattct atccaaacaa acatgcccct
    43081 tgagaccatg ataaacttgg tcaatgctca gttagaaagt ggtggaacgt acaaagtaaa
    43141 ttcgcaagac ttgaagggta ggggacggac ggatcttcct tcctatgcga tgccagatag
    43201 taacctctat atgatggaaa ttaacgacag tagccttgca tctgtcaaaa ctgctattca
    43261 ggatgtgttg gagggcagat gaaatgattg atattcattc gcacattgtc tttgatgtag
    43321 atgatggtcc caagtcaaga gaggaaagta aggctctctt gacagaagcc tacaggcagg
    43381 gggtgcgaac cattgtctct acctctcacc gtcgcaaggg catgtttgaa actccagaag
    43441 agaagatagc agaaaacttt cttcaggttc gggaaatagc taaggaagtc gcgagtgact
    43501 tggtcattgc ttatggggcc gaaatttact acacaccaga tgttttgggt aagctggaaa
    43561 aaaatcggat tccgaccctc aataatagtc gttatgcctt gatagagttt agtatgaaca
    43621 ccccttatcg cgatattcat agtgctttga ttaaaatatt gatgttggga attactccag
    43681 tcattgccca catcgagcgc tatgatgctc ttgaaaataa tgaaaaacgc gttcgagagc
    43741 tgattaatat gggctgttac acgcaagtaa atagttcaca tgtcctcaaa tccaaacttt
    43801 ttggagaacc ttataaattc atgaaaaaaa gagctcagta tttcttggag cgtgatttgg
    43861 ttcatgtgat tgcaagtgat atgcataatg tggacagcag acctccccat atggcagaag
    43921 catatgacct tgtttcccaa aaatacggag aaacgaaggc tcaggacctt tttatagaca
    43981 atcctcgaaa aattgtaatg gatcaactaa tttaggagaa ataatgaaag aacaaaacac
    44041 gatagaaatc gatgtatttc aattacttaa aaccttgtgg aaacacaagc taatcatttt
    44101 attagtggca cttgtgacag gggcgggagc ttttgcatat agcattttta ttgttaagcc
    44161 agaatataca agcaccacgc gtatttacgt agtcaatcgt aatcaagaaa ataagccggg
    44221 actgacgaat caggacttgc aggcaggaac ttatctggta aaagactacc acgaaattat
    44281 cctttcgcaa gatgtattgg aaaaggtagc gacaaatttg aaattggata ttccagtaaa
    44341 aacgttaact agcaaagtgc aagtgactgt accagccgac actcgtatcg tctcaatctc
    44401 tgtcaaggat aaacaaccag aggaagccag tcgcattgct aattctatac gagaagttgc
    44461 tgcagaaaag atcatcgctg taacgcgagt atctgatgta acgacgcttg aagaagcgcg
    44521 accagctacg actccctctt ctccaaatgt tcgacgcaac accttagttg gttttcttgg
    44581 agccgccgcc gtaacagtaa ttactgttct tttgattgag ttgttcgata cccgtgtaaa
    44641 acgtcctgaa gaagttgaag atgtactgca aatgccactt ctaggagtcg ttccagattt
    44701 taataaaatg aaataggagg aagttatgcc aacgttagaa atctcacagg cgaaattaga
    44761 acttgcgaaa aagacagagg aatattataa tgctttgtgc acgaacctac agttaagtgg
    44821 agatgatttg aaagtatttt ctatcagttc tgtgaaagca ggagaaggaa aaacaacgac
    44881 ttccaccaat atcgcttggg cttttgcgca tgcaggttac aaaacgctgc tgattgatgc
    44941 agacatgcgt aactccgtta tgtcaggtgt ctttaaatca agggaaagga ttactgggct
    45001 aacagaattt ctatcaggga caacagacct gtcacagggg ctttgcgata ccaatgttga
    45061 gaatctcttt gtgattcagg ctggctctgt gtcaccaaat ccgatagccc ttcttcaaag
    45121 taagaatttc agtacaatgc ttggaacctt gcgtaaatat tttgactata tcgtcgtaga
    45181 cactgctcct atcggtatcg tgattgatgc ggctatcatt atgcagaaat gtgatgcttc
    45241 tattttagtg acgaaggcag gtgaaacaaa acgacgggaa cttcaaaaag cgaaagaaca
    45301 gttggaacaa actgggaagt cgtgtttagg agttgtgttg aataaattcg atacttcagt
    45361 agacaaatac ggtttttatg ggagttatgg gagttacagg aaacagaaaa aataggttga
    45421 gggatagaga tgaatgaaaa actagcaaag tcttcagtag ctatagtcca gagttttctt
    45481 gttattttat tgacttatct acttagcgct gtgagagaaa cagagattgt ttcaacaaca
    45541 gctattgtac tttatatcct ccactatttt gtcttttata tcagtgatta tggacggaat
    45601 ttctttaaaa ggagatattt gattgaactt gtccagacat tgaaatatat cctattcttt
    45661 gcgctagcga ttagtatttc taattttttc ttagaggatc gatttagtat ttccagacga
    45721 ggcatgattt acttcctcct attacatgtt ttcttagtct atatgctaaa cctatttatc
    45781 aagtggtatt ggaagcgggc ttatcccaac tttaaaggaa gtaagaaggt tttcctactt
    45841 acagcaactt ctcatgtcga aaaggtactg gatagactaa tagaatcaga tgatgttgtt
    45901 ggggagttgg tagccgtcag tgttttagat aaaccagatt ttcagcatga tgatttaaag
    45961 gttgtagcag agggggagat cgtaaacttt gcgactcgtg aggtggtcga tgaagtcttt
    46021 atcaatcttc caagtgaaaa atacaatatt ggagagcttg tctctcagtt tgaaacgatg
    46081 ggaattgatg taacagtcaa tctaaatgct ttcgattggg cacgtaacaa gcaaatttgt
    46141 gagatggcag gactaaatgt tgtgactttt tctacaacat tttataagac tagccatgtg
    46201 attgctaagc gggttattga tattatcggt tccctggtag gtttgatact atgtggtcta
    46261 gtcagtattg tgctggttcc tttgattcga aaggatgggg gctctgctat ttttgctcag
    46321 acgcgtatag gaaaaaatgg ccgccatttc actttttaca agtttcgctc tatgtgtgta
    46381 gatgctgagg ataaaaagag agaactcatg gaacaaaata ccatgcaggg tggaatgttt
    46441 aaggtggacg atgatcctcg tatcacgaaa attggtcatt ttatacggaa gacgagcttg
    46501 gacgagctac cacagtttta taatgttcta aagggagata tgagtttggt aggtacacga
    46561 ccaccaacag tggacgagta tgaacactat accccagaac aaaaacgtcg gctaagtttt
    46621 aaacctggta taacaggctt atggcaggtc agtggacgaa gtgaaatcaa aaatttcgat
    46681 gaagttgtca aattagatgt ggtctatatt gatggttgga caatctggaa agatattgaa
    46741 attttattga agacagttaa agttgtattg atgaaggatg gagcgaaata gtttgctttt
    46801 gtttcagact attaggagaa aaatgaagaa gtcagtttat atcattggtt caaaagggat
    46861 tcccgctaag tatgggggct ttgaaacctt tgttgagaaa ttaacagaat atcaaaaaga
    46921 tggtaacatc caatactatg ttgcctgcat gcgcgaaaat tctgcaaaat caggatttac
    46981 agcagataca tttgagtaca atgatgctat ttgttacaac attgatgtgc ctaatattgg
    47041 tcctgctaga gccattgctt atgatattgc tgctgtgaat aaagcgattg aaatagctaa
    47101 gaaaaacaaa gatgaagctc ctatttttta cattctagct tgtcgtatcg ggccttttat
    47161 agctagactt aagaaaaaga ttcaagctat cggaggtact ctgtttgtca atccagatgg
    47221 acatgagtgg cttcgggcta aatggagcct gccggttcga aagtattgga aattttcgga
    47281 acagttgatg gtcaaatatg cagatttatt ggtctgtgat agcaaaaata ttgaaaaata
    47341 tatccagaat gactataagc aatatcaacc aaagacgact tatattgctt acgggacgga
    47401 tacaagtccg tctatcctga aatccgaaga tctaaaaatt cgtagttggt atcaggaaaa
    47461 aggacttagc gaaaatggct attatctagt ggtgggacga ttcgtccctg aaaacaacta
    47521 cgaaaccatg attcgtgaat ttatcaaatc taagtccaag aaggactttg tcctcatcac
    47581 aaatgtggag cagaataaat tttacgacca gttgttacag gagactggtt ttgacaaaga
    47641 tcctagggtt aaatttgtag gtactgtcta tgaccaagaa ttgcttaagt acattcgtga
    47701 aaatgctttt gcctatttcc atgggcatga ggttggaggg accaaccctt ctctactaga
    47761 agctctagca tccacaaaac tgaatttgtt gctagatgtt ggttttaacc gtgaggttgg
    47821 tgaagacggg gctatttatt ggagaaaaga taatcttcat aaggttattg aagagagtga
    47881 acaaaaaaca atagaagaaa taaaagaaat agatattcta tctacagagc aggtagaaaa
    47941 aagatttact tgggatttta ttgttaatga atatgaaaat ttatttttac tagggaaata
    48001 attatctaag ttacaaggat tttatttgag gaagctttga tggaagttca tcactttctt
    48061 agacaattat ctaaataact tatgttattc atgaagtttt taaaatgata gatattctcc
    48121 ctttttgcaa agatactaaa attatagaga ggaaatatgc ccagtagttg atagtgtttt
    48181 tgggtagggt taaacgacat agttttaaga caaactggtg gagatttaag aaataagtag
    48241 ttcttattaa atcaaaaacg tgttcttatt ctatattgtc atttagtcaa aggtatcaag
    48301 tatgactatt aaaattaatt atatgttttt tgtttgtctc tcttttttcg gtatagtttt
    48361 aagtagttca caggtaatag tgaatctggg tttgtccagt atagttcagt atatagctta
    48421 ttttttattg ttgctatgta tattttttac cttaattaaa aatagtccgg atgtaatcgc
    48481 taatagaatt gcttattttt ctattatttc atttttgttt atcataggga ttaatttaca
    48541 aaatcttcct ttctcaacaa agatttattt atcgttttcc atgcttatta tttctagtct
    48601 atcgact
//
LOCUS       DAVKXA010000009        47117 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKXA010000009 DAVKXA010000000
VERSION     DAVKXA010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.009"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            42..1055
                     /locus_tag="VW883_000556"
     CDS             42..1055
                     /locus_tag="VW883_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0273741.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTH
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(1100..1519)
                     /locus_tag="VW883_000557"
     CDS             complement(1100..1519)
                     /locus_tag="VW883_000557"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0273742.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(1530..2936)
                     /gene="atpD"
                     /locus_tag="VW883_000558"
     CDS             complement(1530..2936)
                     /gene="atpD"
                     /locus_tag="VW883_000558"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0273743.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(3022..3900)
                     /locus_tag="VW883_000559"
     CDS             complement(3022..3900)
                     /locus_tag="VW883_000559"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0273744.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(3916..5421)
                     /locus_tag="VW883_000560"
     CDS             complement(3916..5421)
                     /locus_tag="VW883_000560"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0273745.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(5436..5972)
                     /locus_tag="VW883_000561"
     CDS             complement(5436..5972)
                     /locus_tag="VW883_000561"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0273746.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVNCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(5972..6466)
                     /gene="atpF"
                     /locus_tag="VW883_000562"
     CDS             complement(5972..6466)
                     /gene="atpF"
                     /locus_tag="VW883_000562"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0273747.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(6480..7196)
                     /gene="atpB"
                     /locus_tag="VW883_000563"
     CDS             complement(6480..7196)
                     /gene="atpB"
                     /locus_tag="VW883_000563"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0273748.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(7231..7431)
                     /locus_tag="VW883_000564"
     CDS             complement(7231..7431)
                     /locus_tag="VW883_000564"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0273749.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(7506..8459)
                     /locus_tag="VW883_000565"
                     /pseudo
     CDS             complement(7506..8459)
                     /locus_tag="VW883_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155340.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(8890..9288)
                     /locus_tag="VW883_000566"
     CDS             complement(8890..9288)
                     /locus_tag="VW883_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273750.1"
                     /translation="MENKESYKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     GFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            9410..9490
                     /locus_tag="VW883_000567"
                     /pseudo
     CDS             9410..9490
                     /locus_tag="VW883_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(9616..10098)
                     /gene="greA"
                     /locus_tag="VW883_000568"
     CDS             complement(9616..10098)
                     /gene="greA"
                     /locus_tag="VW883_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0273751.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(10169..11824)
                     /gene="mltG"
                     /locus_tag="VW883_000569"
     CDS             complement(10169..11824)
                     /gene="mltG"
                     /locus_tag="VW883_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0273752.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPATPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(11905..12399)
                     /locus_tag="VW883_000570"
     CDS             complement(11905..12399)
                     /locus_tag="VW883_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273753.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVDLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(12396..12860)
                     /locus_tag="VW883_000571"
     CDS             complement(12396..12860)
                     /locus_tag="VW883_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273754.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKVIRLESPDELLSYFGMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(12870..14204)
                     /locus_tag="VW883_000572"
     CDS             complement(12870..14204)
                     /locus_tag="VW883_000572"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0273755.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGSDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(14215..14832)
                     /locus_tag="VW883_000573"
     CDS             complement(14215..14832)
                     /locus_tag="VW883_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0273756.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSTPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(14880..17978)
                     /locus_tag="VW883_000574"
     CDS             complement(14880..17978)
                     /locus_tag="VW883_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0273757.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLVSPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(18071..19237)
                     /locus_tag="VW883_000575"
     CDS             complement(18071..19237)
                     /locus_tag="VW883_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0273758.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVLLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(19245..20339)
                     /locus_tag="VW883_000576"
     CDS             complement(19245..20339)
                     /locus_tag="VW883_000576"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0273759.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQTLEG"
     gene            complement(20496..21219)
                     /locus_tag="VW883_000577"
                     /pseudo
     CDS             complement(20496..21219)
                     /locus_tag="VW883_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(21244..22179)
                     /locus_tag="VW883_000578"
                     /pseudo
     CDS             complement(21244..22179)
                     /locus_tag="VW883_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(22351..24309)
                     /locus_tag="VW883_000579"
     CDS             complement(22351..24309)
                     /locus_tag="VW883_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0273760.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(24512..26134)
                     /locus_tag="VW883_000580"
     CDS             complement(24512..26134)
                     /locus_tag="VW883_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0273761.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            26240..27685
                     /locus_tag="VW883_000581"
     CDS             26240..27685
                     /locus_tag="VW883_000581"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0273762.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(27731..27925)
                     /locus_tag="VW883_000582"
     CDS             complement(27731..27925)
                     /locus_tag="VW883_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0273763.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(28026..28621)
                     /locus_tag="VW883_000583"
                     /pseudo
     CDS             complement(28026..28621)
                     /locus_tag="VW883_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(28658..29170)
                     /locus_tag="VW883_000584"
     CDS             complement(28658..29170)
                     /locus_tag="VW883_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0273764.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERTCRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(29257..30192)
                     /locus_tag="VW883_000585"
     CDS             complement(29257..30192)
                     /locus_tag="VW883_000585"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0273765.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(30263..30562)
                     /locus_tag="VW883_000586"
     CDS             complement(30263..30562)
                     /locus_tag="VW883_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0273766.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(30552..31301)
                     /locus_tag="VW883_000587"
     CDS             complement(30552..31301)
                     /locus_tag="VW883_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0273767.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(31355..31714)
                     /locus_tag="VW883_000588"
     CDS             complement(31355..31714)
                     /locus_tag="VW883_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0273768.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(31716..33116)
                     /locus_tag="VW883_000589"
     CDS             complement(31716..33116)
                     /locus_tag="VW883_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0273769.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWVKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(33411..33650)
                     /locus_tag="VW883_000590"
     CDS             complement(33411..33650)
                     /locus_tag="VW883_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0273770.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(33682..34152)
                     /gene="ssbA"
                     /locus_tag="VW883_000591"
     CDS             complement(33682..34152)
                     /gene="ssbA"
                     /locus_tag="VW883_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0273771.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(34164..34454)
                     /locus_tag="VW883_000592"
     CDS             complement(34164..34454)
                     /locus_tag="VW883_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0273772.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(34607..35953)
                     /gene="asnS"
                     /locus_tag="VW883_000593"
     CDS             complement(34607..35953)
                     /gene="asnS"
                     /locus_tag="VW883_000593"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0273773.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(35969..36334)
                     /locus_tag="VW883_000594"
     CDS             complement(35969..36334)
                     /locus_tag="VW883_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0273774.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLVPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(36327..37514)
                     /locus_tag="VW883_000595"
     CDS             complement(36327..37514)
                     /locus_tag="VW883_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0273775.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYSFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(37511..37999)
                     /locus_tag="VW883_000596"
     CDS             complement(37511..37999)
                     /locus_tag="VW883_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0273776.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            38320..38868
                     /locus_tag="VW883_000597"
     CDS             38320..38868
                     /locus_tag="VW883_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0273777.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKVEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(39106..44586)
                     /locus_tag="VW883_000598"
     CDS             complement(39106..44586)
                     /locus_tag="VW883_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0273778.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASTNEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRTAGSGFRAAGPENKPILNPNNTIAFSDISQGSHSFRGIGHSRGGREIHYDVT
                     TVRRGNNINFTINYFAPGNLREFVNNNFILDKGTGYGEPTPATVITPNLRNQVKNISK
                     GGNFVSHSGYSLEAAVETNKSQTITFSLPITNPNGDLSLRLRPVEFNVDQGGSGTGTS
                     NDPYSNSNYYFETDPLYLDANPNQANPLTTSFNTKVDFQTLYIPTTKLAEGVTELVSE
                     GVEGEKSQAYRLHKFGDQYVLGLPVGNATTVTAAKPRVMKYGIGKIAATQNKTGDTNH
                     IKFYLDKDGDGVFNNQDEVILNTDIKDGERGPTGATGAQGPAGPKGADGQRGPAGPQG
                     PKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTN
                     GQSPTITATRSVQNGKNGVLVTITPVEGRPQTTFVEDGQKGADGKTPTVTITEGQNGT
                     HTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDV
                     YVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDG
                     KDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGADGAKGE
                     KGDRGERGLTGAQGAKGADGAAGRDGRDGRDGRDGKDVLNGKVNPEANQGKDGDKYVN
                     TETGDVFVKNNGNWDKEGNIKGSKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPG
                     KDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDEL
                     LGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVD
                     GKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITT
                     QRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAA
                     TPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTH
                     TITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKD
                     GKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTIT
                     NPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPK
                     VTITDEQNGTHKISVLNGDGTTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSE
                     TTVRDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIK
                     VTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVS
                     PTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKCGCQDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVSTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            44802..46286
                     /locus_tag="VW883_000599"
     CDS             44802..46286
                     /locus_tag="VW883_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0273779.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYHFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            complement(46337..47065)
                     /gene="yaaA"
                     /locus_tag="VW883_000600"
     CDS             complement(46337..47065)
                     /gene="yaaA"
                     /locus_tag="VW883_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0273780.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
BASE COUNT        13351 a        10452 c         8646 g        14668 t
ORIGIN      
        1 tttgtgatat aatagtctta tctttacaca gaggtatagt aatgaaagaa actgtttatt
       61 ttggaactta tacacgtcgt acttctcaag ggatttacaa ggcagacttt gatacagaaa
      121 ctggtcagct ttcaaatcta gaactttttg cagctgagcc aagtccaacc caccttgcct
      181 ttgaccagca ccaacattta tacactgttg gtagccaaga cgataagggg ggaattgcag
      241 cctatcaaac tgacgggact gtgttaaatc atgttgttga agaaggagct ccccactgtt
      301 atgttgctgt cgatgaaaag cgtgatttgg tttacgcagc taactatcac aagggacaag
      361 tccttgttta taaacgccag gaagatggta gtcttctact tagtgatatg gatcaacaca
      421 gtggccaagg tccacatgaa aatcaagctt ccccccatgt tcactataca gatttaacac
      481 ctgaccacta tctagtgacc tgcgacttgg gaactgacca agtcatcacc tatgacctcg
      541 atcaagaagg aaagttatct aagctctata cctatcacag caagccagga gcaggctcac
      601 gccatatcat tttccataac cactataaaa tcgcttatct catttgtgaa ctcaatagta
      661 ctatcgaagt tttaatctac gatggcgttg gcgaatttga acgtatgcag gtcatttcaa
      721 ctttaccgga agcttacgaa ggctttaatg gaaccgctgc tattcatctc tctaaagacg
      781 gtaaatacct ctacgcttct aaccgtggcc atgattctat cgcagtatat accatccttg
      841 cggacggtag cttagagtta ttagaaatcg ttccaacgca tggtcagact ccacgtgatt
      901 ttgatttgac acccgaccaa aaatttctca ttgttgtcca tcaagactct gacaatgcaa
      961 ctgtctttaa acgtaattgt gacaatggtc gtctagcaga actctccaac gacttccatg
     1021 ttcccgaagc agtctgcatc cgttttgctc cttaaaacac cataaaaaat gaacttggta
     1081 ttttcaagtt cattttttct tatagtctat ttccgacatt aatacggtta atagcacgtt
     1141 gcaaagcaat cttagcacga cgttcttggt caatcaaatg tttgtcttgt gcttcttcaa
     1201 ttgcacgttc tgcacgaagt ttggcacgtt ctgcacgact gatatcgata tcacgagcac
     1261 gttctgcaga gtcagcgacg attgtgatca tatcattggc aatttcaata acgccaccgt
     1321 ttactgcaat ccagttcacg tgatctttat catcgatacg ttttaccttt acttcatcaa
     1381 ctgctaaaac cgcaatcata ttttcatgtc gtggcaagat ccccatctca ccatccagag
     1441 ttcgaaccga tacatagctg gcatggtgat catagacgag accatctggt gtcacgatct
     1501 ggacagttaa ctgagccata gatcacctct taaaatccca ttttttcagc ttttgcaatc
     1561 acatcttcga tagaacctac accacggaag gcatcttctg gcaagtggtc gtatttacca
     1621 tcaaggattt ccttaaagcc acgtacagtt tcagcaactg gaacataaga acctggctga
     1681 ccagtaaatt gttccgcaac gttgaagttt tgtgacaaga agaactggat acgacgggcg
     1741 cgagcaacca aggtcttttc ttcatcagaa agttcatcca taccaaggat agcaatgata
     1801 tcttgcaatt catggtaacg ttgaaggaca cgttttactt cagcagcaac tgcatagtgc
     1861 tcttctccaa cgatttcagg tgccaaggca cgtgagcttg aagcaagtgg gtcaacggct
     1921 gggtagatac ccaattgtac caacttacgt tccaagtttg ttgttgaatc caagtgagcg
     1981 aaggctgttg ctggcgctgg gtcagtatag tcatccgctg gcacatagat agcctggata
     2041 gaggttacag aacccttctt ggttgatgtg atacgttctt gcaattgacc catttccgta
     2101 gcaagtgttg gttggtaacc aacggctgat ggcatacgac ccaaaagggc agatacttct
     2161 gaaccagcct gagtgaaacg gaagatatta tcgataaaga gaagcacgtc ttggccttcc
     2221 acatcacgga agtattcagc gattgtcaaa ccagtaaggg caacacgcat acgtgctcct
     2281 ggtggctcat tcatctgacc aaagaccatg gctgttttct cgataacgcc tgattctttc
     2341 atttcccagt aaaggtcatt cccctcacga gtacgttccc caacaccagc aaatactgaa
     2401 ataccaccgt gctcttgggc aatgttgtga atcaattctt ggattaagac agttttacca
     2461 actccggcac caccgaaaag tccaacttta ccacctttaa ggtaaggggc aagaaggtca
     2521 ataaccttga tccctgtttc aaggatttca gaagaggtag acaactcatc aaaagttgga
     2581 gcttttttat gaattggctg acgctctgcg tcttctgtaa aaggagcttc caagtcaatg
     2641 gtatctccca aaacgttgaa gacacgtccc aaagtttctt tacctactgg tacagagatt
     2701 ggacgacctg tgtccaatac ttccattcca cgagtcaacc catctgttga ttccatggcg
     2761 atagtacgaa ccataccatc tcctaactcc aaggctactt caaggacgat ttttgttttt
     2821 ctttcgtcat ttttgtagac gacaagtgca ttgttaatct caggaagttt ttcccctgct
     2881 gcaaacaaaa cgtctacaac gggaccgata acctgagcaa ttttacctga actcatctcc
     2941 ttctcctatt ctatataaga tactgtcggt tcctagctca actaggtcct aagttcattt
     3001 tcatacgagc tggactagag cctattctaa ggcactagca cctgctacga tttctgtaat
     3061 ttcttgtgta atcgccgcct gtctggcacg gttatactga attgttaaat cattgatgac
     3121 tttcttagca ttatctgtcg ctgtttgcat ggctgtcata cccgcagcat tctcagctgt
     3181 cttggcatcg ataatggcac cgtaaatcat actttctgca aactgaggca acaactgctc
     3241 cagaatttct tctcggctgg tttccaattc aaaagtcaag ctgtactctt catccgcttc
     3301 atttggatcc aagtcaacaa tcggaagcat ttgttccaca cgcatttgac tggttagcgt
     3361 attgacatgg tggttgtagc aaacataaag ctcatcaaag agttcatttt ggtacatttc
     3421 aacagttttt gaaataatct tacgaacttg atcaaagcta ggttggtctg ccaagccacg
     3481 taattcataa agtggttgaa taccgcgagc cttaaagaaa tcagctccca tcccaccgat
     3541 acagatcatt tcaaaacctt taccgtctgg gtggtattct tctttcaact ccataacagc
     3601 tttcaaaata gaggaattat aacctccaac caaaccgcgg tctgaagtga taacgatata
     3661 gcctgtcttc ttcacagaac ggctaatcaa catcggatta gttgaagcac cagctccatt
     3721 accatgaagg atatctgtca aaagtttacg cactttctga gcgtaaactt ggaagttgcg
     3781 agcagcttct tcagagcgac ctaacttagc agccgatacc atttgcatgg cattagtgat
     3841 ttgactcgta ttttttgttg aggcgatttt tgttttaata tcatttagag acactgccat
     3901 ctgacacctc tattcttatt ggaagctaga ttgattgaga aactctgtaa tcgcagcatc
     3961 caagactgct tcttctggca agtcttttgt atcacgaatg gtttccaaaa tctctggatg
     4021 ttgagcatca aagaaggcat ggaactcttc ctcgaaacga acaatatcat ctactggaac
     4081 agtatccaag aaaccatgtg tcaaagcata aagaatggtt acttgtttct caacaggtaa
     4141 tggtttgtga acaggttgtt tcaagacctc aacggtacga cgtccacggt tcaacttagc
     4201 ctgtgttgct gcgtccaagt cagaaccaaa cttagtaaag gcttccaact cacggtatga
     4261 agcaaggtcg atacgaagtg taccagcaac cttcttcatg gctttgattt gtgcagaacc
     4321 acctacacga gatacagatg aacccgcatc gatggctgga cgaatacctg cattgaagag
     4381 gccatcgcca aggaagattt gtccatcagt gatagaaatc acgttggttg cgatataggc
     4441 tgagatatct cctgcttgtg tctcgataaa tggtagggct gtaattgatc caccaccaag
     4501 ttcatcagaa actttagctg agcgctcaag caaacggctg tggagataga aaacatcccc
     4561 tgggaaggct tcacgacctg gaggacgacg aagcaagagc gacagttcac gataagctac
     4621 cgcttgtttt gatagatcat cgtatacaat caaaacatgc ttaccttgat acataaattc
     4681 ttccgccata gcgaccccag tataaggagc taggaagagc aatggagatg gttgtgaagc
     4741 agaggctgtc acaacgattg tgtagtccaa ggcaccgtac tgacgaagtg tttctacttg
     4801 cgtacgaact gttgattctt tttgtccaat cgcgacgtag atacagatca tatcttgatc
     4861 tttttggttc aagattgtat caatcgcaat ggttgttttc cctgtctgac ggtcaccgat
     4921 aatcaactca cgttgaccac gaccaatcgg tacaagggcg tcaatagctt tcaaaccagt
     4981 ttgcaatggt tctgaaacag acttacgttg cataacacca ggagctggtg cttctactgg
     5041 acgagtttta tcagtgtgga tttctccaag accgtcaact ggacgaccaa gcggatccac
     5101 aacacgacca atcagacttt cacctacagg gacttccatg attttccctg tacggcggat
     5161 tgtatcgcct tcacggatat ctgtaaagtc acctaggatg ataataccaa cgtctgttga
     5221 ctccaagttt tgagccatac cataagagcc gttttcaaaa ttcaacaact ctccactcat
     5281 gacattttca aggccgtgag cacgcgcgat accgtccccg atataggtta caacacctgt
     5341 ttcagtcaca tcaaaattgg gtttgaaatt ttcaatttgt tgcttaatta aagcgctgat
     5401 ttcttgtgcg ttaattgcca aaagaacacc actttctatt tcaaattttc tttaacaact
     5461 ttaagttgtt gtttaatact cacatcaatt gtcttgtgat tggcaaaaat gacaaaacca
     5521 ccaatgagac tttcatcgat ttgttctttt acactcctta ctttcagaga catttttttc
     5581 tcaatcaaag ggagcaaacg agtcttctgt tcatcagtta gaggatgagc agacgtaatc
     5641 gtcacttcaa atcgatttgt ttctttttca agtcggttca agcaatttac aagcacatca
     5701 taaaaaagat ttgctctgtg attgtaggcc agaacctgga taaagttttg taataaaggc
     5761 gacacagaat cttggaaaaa agcaattgtt ttttccttat ccgactcgtc tactgccact
     5821 tgttttaaaa aagaaggcag acctgttttt tcaacaactt gcttgatttg agtcaagtct
     5881 gaaaagatac ggtcttcttc tcctttttca agtaccaatt ggacaaaagg catgctgtat
     5941 ttttcaatta cctttactgt tttcttgtcc attaagcttc tcctagctga tcgatatact
     6001 gatcaatgag tgctttatgg gcatgactgt caaggttttg tgagatgatt ttaccagcta
     6061 agctgatggt caaatctgcg acctcaccct taacactctg taaagcttct actttatttt
     6121 gagcaatttc ttgattggct ttttctttta agtgtcctgc ttctagttta gcatctgcta
     6181 agatattagc cttactttgc tcagctgttt cctttgcatt ttcaatgatt gtcttagctt
     6241 ctttacggct accagccaat tcatcttcgc gtttttgagc caatacttct gctttttgac
     6301 gggcttcttc agctctgtca atatctgaag caattttttc agctctttct tcgaaaatgc
     6361 ctgtaatatt agaccatgca aattttttaa tcaagactag caaaagaata aaagagccag
     6421 tgattaaaat aaaattacca attaattcac ctactgttac gtgcatcagt tactcctttc
     6481 tattcctctt caatattaat cttattccct aaatacacag atgtcaaaag agtaaaaaca
     6541 taagcttgga tgcaggaaat aaagacagaa aatgcagtcc aagccaaatt agctccaaag
     6601 gctactggat accaataaat agcttggtgg gaaagaagaa gtaacaaact cgtcatgacc
     6661 tctcctgcaa agatattccc aaaaatccgc aaagccaaag ataagaagtt tgtaaattct
     6721 tccaagatat tcatcggtat gacaaaaaca ggactcataa aagattttat acttttttta
     6781 aatccacgac gacgaacgct ttctatatgt gtcaacaaaa tgacaagaaa agataaggtt
     6841 aagtcatact gtaaattagc ggttggcgaa ctccaccagt tagtcccatc gatcgtttga
     6901 agctttgtca ttaagccaag gttattggca atcaccatga aaaggaataa acaaaggaaa
     6961 aagagtgagt aatctttcat gtagcgcgaa ccaatgttag gttctgtaaa tccaataaca
     7021 aagtcataga catactcaag tacattttgc tttcctttgg gtttcaaggt catattgcgg
     7081 cttgcccaat aaataaagac aaaaataact cccacaatca acaaagtcat ggctaacata
     7141 gtcagattga agataacagg accaatagag atgattggat taatactttc ttccatctaa
     7201 aatcctccct tttcttctcg ttccatgtat ttatttgata ataaatgaga agacaagagt
     7261 tacaaagaaa gttccttcaa taaaggcaac acctaaaaac atcaaactac gaaactcaga
     7321 aagcatatct ggttggcgtg ctactgattt aaacagtcca ttcatcaata aaccttcacc
     7381 gacagatacg cccatacagg caatacataa gcctaaaaat gttaaattca taacaaattc
     7441 tcctttaaaa taaaatttac ttacttagtg tagtcctaaa atttaaattt gtcaactttt
     7501 aaccgctatt ggaagcgttt aataaaaatt atttccattt tgctaaattt caagttcaag
     7561 ttagccatcc aaaagtcttc tctgggtgac ttgtagtcca agcatttttt aggatagttg
     7621 ttaatccact tttcgatgaa tgcgacttct ttgggagtca ttttcttggt tcccttaggt
     7681 aaccatctac gaatgagcct gttgtgattc tcattagttc ccctttccca agaggcatag
     7741 ggatgtgcat aataaatgtg ctcctcagaa aatacattag acaagcgatt gaattccgtt
     7801 ccattatctg ccgtgatgga aagaatcttg tgttgtttta agatgagttt tagagcctga
     7861 ttgaccacct cagcactttt atttggaatc aatcggatga tctgatgtct actttttcga
     7921 tccgtcaaga caagcaagca gtagtttttc gctctcgtaa gtagaactgt atcaatctca
     7981 taatgcccat tctccaagcg aaaattgata gcttcaagcc gctgttcgat ggattgacca
     8041 gcaggtttaa agttggtgct ggcctgtttc ttaagcgctt ttccttttct agggtaaagc
     8101 agatcctgct tgctttaccc caattttcca tgatgaatcc aatagtaaat ggttgaaatt
     8161 cccacgttaa cccctttagc cataaccatc atttcaggca aaaatttttg gttatgatag
     8221 tggagaatct tttcctttag ttccttggtc acgcttgatc tcttgaccga gtgcttgcga
     8281 ttattttcat aagactgttg agcatagtcg gcagaataaa cctctttgaa gcgccctttt
     8341 ccaagacatt ttcggactgt cctacgcttg atttcagtgt ggatagtttg aggagctttt
     8401 ccaagtagag aggcaatttc tctatttgat ttccctttgt tcgccttttg tagtataatg
     8461 gttttgcatc tctgtgcctt tcttgtgttt gtggttgaac aacaagtata acacaaaggt
     8521 gttttcttat gcctacaaga gctttcatta tttccatttt cttttggatt tcactctatt
     8581 ctgaaaaact tgtgtatatt tactgaagct agcaagtctt acctgtaaat ttaatgaaag
     8641 caacacaaaa tccgagaggg gaatctcgga ttaatgtcaa tttaaaaaga tagagagttt
     8701 ttagtttaaa taaattgttt taaaatatca acaacatcac ttcttttctt aacctgataa
     8761 gccttgattc ctaattttgg ggctacgatt atattgtcct caatatcgtc tagaaagaca
     8821 caatttctag gttataactg gtatttatcg atagttactc atatatatca gtccacctcc
     8881 atactcacct tacagattct tttgataata atatctttgc ctaatgtaga gatagtcttg
     8941 caaagaaaaa acttccttgt agccatgttt ctgataaaag cccggtgcct ggaactggta
     9001 agtattgaca aaggcaaaac aacaatttcg atttttagct tcactttctg cctgttgcaa
     9061 tagttttgaa ccgattcctt gccctcgcag ttcctctttt acaaacaaat actcgatttc
     9121 tagccaattt ccaaaagtct ctgctatcaa acccgcaagg agattgccct tttcatcttc
     9181 gacataaaga ttaagtggct cactttcagc ctcttctctt tttgaacggt tataaacacg
     9241 aatcagattc cctatttctt gcgatttata tgattcctta ttttccaatc taaagtataa
     9301 tgaaatgaaa taaaacatgc gcaaatcgat taaggaattt aatctaattt ctaacaatgt
     9361 cttagaaatc aaagtgtact attttaactt caatgcacta tacatctaat actcaatgaa
     9421 aatcaaagaa cagactagga aactagccgc aggttgctca aaacactgtt ttgaggttgt
     9481 agatgaaact gacgaagtca gtaaccatat atacggcaag gcgacgctga cgtggtttga
     9541 agagattttc gaagagtagc aaaatggaaa aaggagtgag tgaagcacat cgcctcccca
     9601 ctcctttttc tgtttttagg ctgttttttc aaccttcaag atttttacat catagctacc
     9661 aacaggcgtt tcaattgttg ctgtgtcacc tgttttcttg ccaatcaagg cctgcccaat
     9721 tgggctttca tttgaaacct tacctgcaaa ggcatccgca ccagctgaac ctacgataat
     9781 ataaacttct tcttcgtcct cgccaatttc ttggatggtg actgttttac caatcgctac
     9841 ttcgtcctgg gcaactgcgt cgctattgac gatttcagca tagcggattt ttgtttctaa
     9901 gctagagatt tgtccttcga caaaggcttg ttcatcctta gctgcttcgt actcactgtt
     9961 ttctgaaaga tcaccgtatg aacgggcaat cttaatgcgt tctaccactt ctggtcgacg
    10021 aaccaatttc aattcttcta attctttttc aagtttctcc ttttcctcaa gggtcatagg
    10081 atatgttttt tctgccattt ttctcaactt tcttctgata atattttcta aagaaaatta
    10141 tgtgaagtat cacataattt tagtttgttt agtttaattt gctgttgaca tgttcagcga
    10201 cattgcggtc gtggtcttct tgattgttag catagtagac cttgccttct gtgacatctg
    10261 ctacaaagta gaggttatcg ctcttagttt gattgatgct tgactcaatc gcatccagac
    10321 ttggactatc gactggacca ggcatgagac ctacattttt ataaacatta taaggtgaat
    10381 caatgttggt atcaatcgca acatcctcag ctagactgat attttgcccc agttttcctt
    10441 gggcatacaa gattgcaata ttactttgaa gtggcatatc acgattcaaa cgattgtaga
    10501 atacacctgc aatgagctta cgatcttctg tcttggcacc ttctttttcg accaaggaag
    10561 caatggtcaa caactcattg acagtcaagt ttttagattt gatagtacta tagtaaggag
    10621 ataggttctt atccatagca gctaacatct catcaatcaa gctctcaata gttgtgcttt
    10681 ccttgataga gtatgtagct gggaaaaggt atccttccaa acgataacgc gcaccgctgt
    10741 cttttacagg caaactttcc agtaaagtag gatatttcgc tactgcttga ctgataaacg
    10801 tctcatcttg aactttagcc aagaaagtct ccgctgtcaa agactctttg aagtcacctt
    10861 gcaattgacc cacagcttga gcaatctgat ccaaggtata accttctgga attgtcaaag
    10921 tcgcaagtac aggttcttgc ggttcatctg ttccaccttt ttgcaactct ttgagtaagt
    10981 cttctgtact catactcttt tgcaaattgt agtaacctgc tttcaagtcg gtataatttt
    11041 tatacttggc ataaaaacta aaaatcagac catgctttac caaaccagct ttttcaagcg
    11101 tcgtaccgat ttcttgaacg tttgaacctt ctggaattcc aaccgtcaca tatttcttag
    11161 aattagcatc gataggtaac aaagaatcta gcacgtactg gtaaccaaag taaccacctg
    11221 ctgagagcaa ggcaaggaat acaaggaatg aaatcacaaa agctttcaca tgtgacttct
    11281 tctctttctt aggcttaacg ggttttgctc cttctctacg gctacgacgt gatgtatcgc
    11341 tgatgatatc cactgtttct gtagcaggcg taggtgttgc tggacctgct tgttctgctt
    11401 ttttctctgc cgtcgtatag gaaacagcta cccttgttgg ggtttcattg tattctcttt
    11461 caagtttctt aggtctaaca ggacctggac ctggtcttga tccactttct tccgctggag
    11521 aagaaggtac atcttgactt ggatgacttg gaacaccagg agtttctctt tgaatctcat
    11581 ctgctggaga agctggtaca ccttgacttg ggtgagtagg cacggtagga gcttttctca
    11641 taatctcctc taccgttgac aaggaatcag ccatgagttc ttcagctgaa ggttcatttg
    11701 caggagtgcg aactactgcc tcatcttctt tcagaacttc atcatagcct tttacttttt
    11761 ctaaatctct cagaatctgc tctttaaagc ttaatttctc ttcttctctt gacttttcac
    11821 tcaaaagttt ttcctccttg ttgataatcc ataatattat atcttaaaag tccaaaaaaa
    11881 gcaatctatg atacttttcc taacttattt tttcatttcc cagaccatat cataccatgt
    11941 ttcccctgca aaggttgact gggactggcc ttcgttgaca aatccatgtt tttcataata
    12001 ggcgatgaga tagtcatgac aggttagatt aatgccatct ctctcatctt caagagcaac
    12061 ttctttcaag gctgtcagca atttctgacc cagtccgagt ccctgtgcct ccttggcaat
    12121 agacagacag gtcacagaga tataaccacc aggctcatga ctatagtctt ttatttcttc
    12181 tgtaaaagac tggtcttgca gatggcggtg caggtcaact ggtccttcga tataacccat
    12241 gattcttcct tctttttcag caaccagaaa agaggtctga atttctctca aatgtgcttc
    12301 aaagacagaa ggaggaatgg cttcttcgac cgaaaaattt tcaaattcaa gttcaacaat
    12361 ccgatccaaa tcttctaatc ttgcttgtct gattttcatt gttcctccag ataaaaggga
    12421 ttaaaccaaa tcatactata gccctggcta gttgcataga gcaaagtttc ttcttcatca
    12481 acaaaaccgt tcattccaaa ataggaaagc agctcatcag gactctccaa acgaatcact
    12541 ttgtaatcca gctcaactgc cacctctttc aaggctgcaa gaagaagtgt tcccaggccc
    12601 tgtctctgat ggtcagactc gatgactaaa gaatgtactt ttagacattg cggattgtct
    12661 gactggggac ttgataaaat atagcctaaa agttgatttt catccctagc tagaagaaag
    12721 gtatccgcac acttacggat actttcttct aaaatatggg aaagttgctg cttttcagct
    12781 ggaaaagacg aggtctgaag tgcccctatc tcaggcaaat cagacttgct tgcctgaatg
    12841 atcttaattg gaatttccat gggaacatcc tattgaacat tgcttgtcaa gttagacaag
    12901 agacgctcaa atgagtattc ataggtttgg atgtctcctg ctcccataaa gacgtaaaca
    12961 gcattgtcat ggtctaggag tggagaaaca ttttcaacag taatcacttg gtgttttttg
    13021 ttgattttgt tggctaggtc ttctacctta acgtcaccat gatctacttc acgagccgag
    13081 ccataaattt gcgctagata aacagcatct gcttggttta aagcatgggc aaagtcgtcc
    13141 aacaaggcaa tggttcttgt aaaggtatgc ggttgaaaga ctgctacaat ttccttgctt
    13201 gggtatttct gacgagccgc atccaaggtc gcaataattt ctgttggatg atgggcaaag
    13261 tcatcaataa tcactgtatc attgacaatt ttctcagtga aacgacgttt aacaccggca
    13321 aatgttttca agtgctcacg caccaagttc aaatcaaatc ctgctgtgta aagaagacca
    13381 ataacggctg tcgcattcat gatattgtga cgaccaaagg ttggaatgtg gaattgcccc
    13441 aagttttgtc cacggaaatg aacggtgaag gttgaaccag ttgttgaacg aagaagatca
    13501 ctagctacaa agtcactgcc ttcagcttca aaaccataat aataaattgg tgcatcagac
    13561 gtaatcttac gcaattcagc atcttcacca tagacaaaaa gacccttggt aatttgtttg
    13621 gcatagtcgt taaaggcatt gaaaacatcc tcgagacttg tgaaataatc tggatggtca
    13681 aagtcaatgt tggtgataat agagtattct gggtggtaag gcatgaagtg acgctcatat
    13741 tcgtcagatt caaagacaaa atatttggca ttagccgaac cacgacctgt cccatctcca
    13801 atcaagaagc tggtatctgt aatgtgagac aagacatgag acaacatacc tgtcgttgaa
    13861 gtttttccat gtgctcctgc tactcccatg ctaacaaagt cacgcataaa gctacctaga
    13921 aactcatggt aacgtttgta gctgatacca ttttggtccg cataggcaat ttcgacgttg
    13981 ttatctggac gaaaggcatt tccagcgata atttccatat caccgtctag attcttttca
    14041 tcaaaaggaa gaatggtaat tcctgcctgc tcaagaccgc gttgggtaaa gtagtacttt
    14101 tcaacatctg atccctgaac cttgtgcccc atctggtgca acatcaaggc caaggcactc
    14161 atccctgatc ccttaattcc gataaaatga tatgtctttg acatgttttc tcccctattc
    14221 tgtcattctg gtcagattca actcttgggc aacccgacgt tcttgttctg tttgtttact
    14281 ttttttattg tagatttggc tcttctttag aaaatcataa ttgtttttct ttggagcagg
    14341 tgttgacact tcttcattct tggtagggat agaatgaact tcttccgcca agatataatg
    14401 agactgggtc aatttttggc tatatttgac aaattcacca ggattttcct tttggaaagg
    14461 agttgtcggt tgattgccct gtctaactag actgggctga gaatgacgtc tcgcaaggct
    14521 gaaatcctga gttaggtagt tagcagagcg tttctttttc aagtccgcac gcgcttcttc
    14581 acgcgccacc tccgcatagc tctttccttc ttttttaacc cctaaaggag cctttttagg
    14641 tttttcgact tgcttttcaa tcggttttac tggtttttct tcagtaatag gagcccattc
    14701 taaataattt ttatctcgat actcaccctt gatattactg atcagatcag actcatcata
    14761 gagattcatg actggcattt cagtcaacat gacctcgtca tctgacacca atggaaatcg
    14821 ttcttgtttc attttctatt tcctttcaac acttcattat agcgtattgt cttgattttt
    14881 caagtgctgg cttcagaaat tcccaaaatt tctctaattt ctgctagggt cagactacca
    14941 cgtgactctg tgccatccaa tacttgtgac accagatgtt tcttttgttc ttggagttcc
    15001 tgaatttttt cttcaatggt tcccttggtc accaagcgat agacctcaac cgtttcttcc
    15061 tgacccatcc gatgggcacg gccaatggct tgcgcttcca ccgcaggatt ccaccaaagg
    15121 tcaaccaaga tcactgtatc tgcacctgtc aggttcagac cgaccccacc agccttgagg
    15181 gaaatcagaa aggcatctct ttctccttgg ttaaaggcct tggtcatgtc ttgtctttcc
    15241 ttggctgggg ttgaacccgt aattttaaag gatgtcaggc ccaagtctgg cagttcttgt
    15301 tcaatttttt ccaacattcc cttgaactga gagaaaatca agacacggtg tccgccgtct
    15361 gccacctgta ccagtaggtc tcggagacta tctagtttgc cgctggctcc ctgataatct
    15421 tccataaaca gggcaggagt gtcacatatt tgacgcaagc gcatcaaacc agataaaatt
    15481 tccacacgac ttcgctgaaa ttcctgttct gacacttgag ccagatggtc tcgcatctgt
    15541 tgtaactggg caaggtaaat agccttttgc tggtcttcca gttcattttt ataaaccacc
    15601 tcaatcaagt ctggcaattc agtcagaact tcttctttct tgcgtcgcat cacgaaaggc
    15661 ttgataaact gagccactcg ctctgctggc aatttcataa attctttctt gcttggcaaa
    15721 agtccgggca tgacgatttg gaaaatagac cacaactcac ccagatggtt ttcaatcgga
    15781 gttcctgaca aggcaaagac cgacggcacc acaaattgtc tcaaggtctg ggcaatcttg
    15841 gtctgggcat ttttcatgac ctgagcctca tctaagaaaa ggaagtcaaa ggccatcccc
    15901 tgataaaact cactgtcctg acggaaggtg gcatagctag tcacatagat ttgatggctc
    15961 tcggcaagaa tctcctcacg acttgctttc aaaccatgaa caacagccac atccaactgt
    16021 ggggcaaatt tctgaaactc atctgcccag ttgtaaatca aacctgacgg agcgagaatc
    16081 aaaacccgac tttcttttgt cacttgacta gtcaaaaaag caatggtctg aagggttttc
    16141 ccaagtccca tatcatcagc caaaatccca ccaaaaccat aatgatggag catctgcaac
    16201 cagccaattc ccttttcctg ataatctcgc aagtcagcct gaacctgagt tgcctgtcga
    16261 ggaaagtcct ctggatgtgt caaatcctgg gccagattct ggaattcttg tgaaaaagaa
    16321 acacggtctc gcccttcaaa gagatgagct aaactgtagg ccaaggattt ccgagcctgc
    16381 aaggtcccat cttttaattc aaattgcccc agttcctgta gattttggcg aattttcttg
    16441 gtttcttcat cgaaaaagta aacttgatta gacgaatcaa tataaaaatc ctgattggca
    16501 accaaggcct gcatggcttg gtcgatttcc tcctgggcaa tatcttgaaa atcaaactgg
    16561 atttccaaga gacctccctt ggaggcaatc tgcacctgag gactcactag gctataaagc
    16621 tcttctagtt tatctgatag gtcaacatgc ccgagttttt caaagactgg aatgatatca
    16681 tgaaaaaaat gatagacaga ctccgctttt aaggcctgac gccaagattg aaaatcggct
    16741 tcaaagcccg cagccaaaca gacttggaaa attctttctt ctaagtccgc gtcacttgaa
    16801 aatggtaatt cttctagctc ttgtcggcta gatacctgtc tatttccata atcaaactga
    16861 atttctaaac gaatccgatt atcttcttcc ctgtcaaagt aaaaagaggg cgcaaaagtt
    16921 ttgatttgta gacgttctgg agctgaaacg gtgcccatct ggataaaaag agtcagacag
    16981 gaggccaatt tgtctcgatc actgctatca aattgcaggt atttctttcc ttgttgaccc
    17041 acaggtaacg ctttaatttc cttgagaaga cgcatctgct ggtctgttaa aaaataaacc
    17101 tgacctttat ggaaaagtac tgctccctga taaaagacat tgaccctagg actctcactg
    17161 atttccattt caaaatagtc cgagtattct gttactgtaa aggcaaatag attggcatca
    17221 gcatgcatat cctgaaaaag cagggtttgg tagctatcca cttgatggtc aaattgaaaa
    17281 tggggcaagg ccatcagtaa attcacaccc tgctcaaaaa aggtcagagg gaaaaagagg
    17341 tgccgacctt ggttttggaa aaagaggtct gaaaccagcc cttcctccgt tagtccgtgc
    17401 aagaaagtca aaagttcttg gctggcatca tcaaaggctt cccaagaaag agactcctca
    17461 taaatcttgc caatcatata cgactttctc tgctcgacaa tccttaaaaa aagtggaata
    17521 tcccgaatga catagtattt ttggctattg atttggccga ttctcagagt ccacaagata
    17581 tgattggttc ctgcttccac ctgacccaca gctgataact cataggcgca ttctgatttt
    17641 ggagataaaa ttcgatccaa aaacttgcca cccaaggtca ccttggtttc aacagcctct
    17701 ttttcttcat gaccttcttc cagactccac aagatttcct gaccacgctc atcatttttc
    17761 agaaaatgct ctagcgctgc caaatgcaca cagtaacccc tcttttgaaa aaaatcacag
    17821 gcacaaaaaa ccaaatcatc ctctaaacta tagcgcagtt cttcttctgc aacgcgagcg
    17881 tagagccgat tgttcttttc cttgatgata tcaaccttac cagtttcata aagggcaaca
    17941 ccttcgatac gaattttccc cggaatcaat ttagccatat tttcaccttt accttatctt
    18001 tttattatac catattttcg cctatgaaaa tagccttcta ggaagacttt tctcctagaa
    18061 ggctggattt ttaacgtttg gcaaaagtag ccacaatccg ctgacagact tcttgcaaca
    18121 gagatttggg catagctata ttgatgcggg catggagact tccttcctct ccaaaatcca
    18181 aaccacggtt gaggataacc ttggcttcat ttctcaacaa ctcttgcaat gtttcatcag
    18241 tcaggtcata agctgaaaag tcaagccaaa tcaagtaggt accttgcggt ttcatgacct
    18301 tgattttagt ctcttttcca aatagatcca ccacataatt gatgtggtct tcaaagactt
    18361 gcttgagttc ctctagccaa tctttaccgt atcgataggc agcttctgtc gccaaataac
    18421 ccaagcctga aatttcatgc tgattattgg ccaacaggcg tttctggaaa gccagtctca
    18481 acttaggatt ttcaatgact gcataggaat tttttgttcc agcaatatta aatgttttag
    18541 tggcactgct caagacgata gcaaaatttt tgaaggcagg attgatggta ttgaaagact
    18601 ggtgtttgtg accaaagagg gtcaaatctt ggtgaatctc atccgaaact aacaaaacac
    18661 cgtgtttttg gcagagttgg ccaatcttct ccaacacttc tttttcccaa acacgtccac
    18721 caggattgtg agggttgcaa agaacataga gtttaacctc ctcttccacc aaatcctttt
    18781 caagttggtc aaagtcaatc tcaaacagac tatccttttc cactaaggaa ttagtaatca
    18841 atctacgatt attcaacttg acactgcgag caaagggtgg gtagacaggc gtgttaatta
    18901 aaaccgcctc gccttctttt gtaaaggttt gaatagctgt tgagatggct ggtaccacac
    18961 cctcgataaa gacaagagcc tctttgtcaa agttgtaacc gtattgtgta gcttcccact
    19021 tttgaacttc cttaattaag tcttcactgg cataggtata accataaacc agttggtctg
    19081 cgtaagtttg cacggcttgg cggatttcag gcaagagcac aaagtccata tccgctatcc
    19141 aagctggtag aacttcacta tccgtttctg tttctttcca tttataggta tggtgcccta
    19201 aacggttggg caggcttgta aaatcatatt ttcccatctt tgtcttatcc ttctaaggtt
    19261 tggcgcaaat ctgcaatcaa atctctagca tcctcaatcc caatagacaa acgcaagagg
    19321 tcatctgtca aaccataaga atggcgtact tctgctggaa tatcagcatg agtttgagtc
    19381 gttggataag taataagact ttccactccg cccaaacttt ccgcaaaaga gaagaccttg
    19441 agactgttca aaatatgagg aatgcgtgtt tcatcggcta ctttaaagga aatcatgcct
    19501 ccacgaccag tgtagagaac ttccttaact gctggagaat ccttcaaaaa ggcaaccact
    19561 tcttgggcgt tagctgttga gcgctccata cgaagagaca aggtcttgag accacgaagc
    19621 aactggtagc tgtcaaatgg agacaagact gcccctgttg tattgagatt gtaaaaaagc
    19681 ttctcgtata gttctaaact attggtcaca accactccag ccaagacatc attgtggcct
    19741 gctagatact tggttgctga atggagaacg atatctgctc catcttcaat cggacgttgg
    19801 tagatagggc tatagaaggt attgtccacc accactttgg cacccttagc atgagccaat
    19861 tttgctagtt tttcgatatc aaattccaac atcaagggat tggttggggt ttcgatatag
    19921 agaacatcca catccttttc taactcggca atcaactctt cttctgtatt ggcataggta
    19981 aaatggaaac gaccttcctg ctccacttgg ttaaaccagc gaaaagaacc accgtaaaga
    20041 tcacgcactg ccaagacctt acttcctact ggaaagacgc taaaggccag tacaatagct
    20101 gacatccctg agctagtcgc tagggcatag tctgctgact caatagccgc caagacttcc
    20161 tcagccttac tacgagttgg atttttagtg cgcgtatagt caaacccagt agatcgacca
    20221 aactctggat gctgataggt cgttgaaaaa tgaagcggtg tcaccaatgc acctgtcgct
    20281 tcatctgact taatacccgc ctgggccaaa attgtgttaa tgtgtaattc cttgctcata
    20341 caatacctcc aaatctatag taactattgt accacttatt ttcatcaact cattttcttc
    20401 ttttcaagag ctagttatag tttcaaacta tataaaaagg gagtttttcc tgctcccttt
    20461 aatagactat aaaatggtga atctcaaaag acacttcact ctatcatttg ctcctgcaca
    20521 aaacgagcat aacgctcatg attttccagt agttccttat gagttcctga gccagtgatt
    20581 ttcccctcct ctaagaagaa aatacaatcc acatctttta ccgttgacaa acgatgcgct
    20641 ataatcacaa ccgtcttctc ctttaataca gaatagaggc tactgataat cgcatactca
    20701 gaatccgcat caagattagc agtggcttca tcaaatataa gaatttcagc atcttttaag
    20761 taggctctag ctatttgaag tctttggctt tgccccccct gacaagagtc gtccgcgttc
    20821 accaacttca gtatctagtc cctctttcat ggagcgaatc tcatcaccta gtgatactaa
    20881 gtctagcact ttcatcaatt catcatcagt tactaagcga ttcaaaccga gacaaagatt
    20941 gtcacgaata ctgccagata agactgcatt attttgtgaa acccaagcga ttttacttct
    21001 ccattctttt aagttaaaat catatatact tgattgctcc attagaatat ctcctgaaag
    21061 cggtttataa aactgctcta acaaacgcac aatcgttgat tttcctgatc cagatggtcc
    21121 aacaaaagca attttttgcc ccttgaaaat tgaacaagta atatccttta agacaggtcg
    21181 attttcatca taaccaaaat agacatggtt aaaattcaac ccttgtcctg ataccgattt
    21241 tcctcactca aatttttctt taggaactgc aagcaagttc tccagtgcaa ctgaagatcc
    21301 cttgctccta gaataaacag ttacaaaatt agctatatta ctaataggat taagtaattg
    21361 aaagaggtaa atcaaaaacg aaaccaaggt tcccacagat atatatcctg cgctgacccg
    21421 ataaccccca taggttagca tcacagctat agccgcaaag ataaataaga gagcaaacga
    21481 ggtctcaaaa gaagtaaccc tatctgattt cagtgaattg ttttgtaccc tttcaataca
    21541 attatccaaa acatcctgta cacttttctc tgcttggtta gtcttaatta attcatgttc
    21601 ttgaatcttt tcagtcaatt gccctgttaa aaatccgatt tcctcctgta aacgacgact
    21661 atacttttca ctgatattgg aaaggggcaa gataataaac atcatacaag gaagagtgat
    21721 gaataaaagt agagaaagat tccaatcaag actaaataag actacaatgg aaccaagtac
    21781 cataactaaa ctcagaataa tatttgggaa agtcgtaatt aaaaactcac gaatgacact
    21841 cgtgtcattg acaatggcag aagtcaactc cccactttag ctcttatcaa agaaggattt
    21901 ctctgcataa atcaacccct ctatcacttt tttcctgatt tttgctatct ttttttcacc
    21961 cgattgacta aacagatagt aaccaataga agaaaacaag gcttgaccaa taaaaatcaa
    22021 aaacgattga aatactttgg aacctatatt ttcaatagaa ctcccatcta ttaaaccttt
    22081 taagataagg ggaagcaaca aagcaagtag actagataga acaaggaaga aactccccat
    22141 aatcacctta gtatctactc ttaataattt taatttcata aatactcctt ataatatttc
    22201 aacggataaa gtcgggaata actcaatttg aggataaaat ctaataaatc ttcctataac
    22261 aaaacgcata acatctagga ttttatatac ctgatattat gcgtttttaa gcacaaagac
    22321 ttcttacaca aacttatcta caattagatt ttatttgaca tgttttgcca attcttcttg
    22381 ggctttttta ttggattctt ctttttcttt caaccatttt tctctagctt ttgcatattc
    22441 gtctgttgtg acaatcttat cttgtacttt gaggtattta tatgattcaa tcccttttgt
    22501 accggttaaa ccataggcag cagcaaatgg tacggttctt ctcaatgatg gtgttccccc
    22561 acgcgaaaca cttggaagaa ctaaagaact atcaatcaac caagcttgaa tatcagcata
    22621 tttctcataa cgtttggctg gatcttgctc tttattagct tcttccaaca tttgagtata
    22681 gacatccagt ccaacttcct tagccttgtc attggcttct ccaggctcta gtccaagatt
    22741 ttgtagaact cctccactat tagtattaaa aatatcgaga taggttgacg ggtcttgata
    22801 atcaggtccc caaccgccat gatataaatc atagtctttc tgagcagctg tttgagcaaa
    22861 gtagcctgaa ctgtcaaact catctgatgt taattgctga atgtcaatca ctacattatc
    22921 agaacctaaa acagattcaa ttgattgttt gatagaacta actccttgta tgcctacttt
    22981 atctgttact tccacagtct tatccaagtg gattgggaat tgaacaccct ttgcttcgag
    23041 ttctttctta gcttccgcaa acttagcctt ggctttctca ggattgtagt aagggtcttg
    23101 accatccgca aagttgatac cttgccattc cttaccatag ttgaccatct tagaggctac
    23161 aacttcacca aagtcttttc ccttgatact gacaaagttt ggaggaacca ctaggttacg
    23221 caaaatcttt gttgcacctt ctttcccttc agactgagcc ccataagatg ttctgtcaaa
    23281 agcaaaattg atagcctgac ggaagttttt attgagaact gcttcctgag tcgatttctt
    23341 ttcaatgtca cttgttttag aagtataatt gtaagacttc ctatctaggt taaaattaaa
    23401 gaaatatgaa gttgaatttt gcatactata tatgatattg tttttgtatt tttctttaat
    23461 cccttcatag ctggagctgt taggaaaaag acgagccgta gtataagcac cagctgtaaa
    23521 attacgttcc agtgattctt ggtcgctacc atcatagtag gtcaatttca catcgtctac
    23581 aaagacattc ttagcatccc agtaattagg gtttttctta tattcaatag cagattttga
    23641 gacaagtgct ttcatcaaga aaggtccatt gtacaaaata ctagatggat ccgccttccc
    23701 aaaatcatcc ccttttgatt tcaggaaatc tgcattaaca ggaaaaagta tcgttgcaag
    23761 tgtttttgaa ttccagtaaa gttctggttt aaccaaagta tattgaaccg tttggtcatc
    23821 aagtgccttg acaccgacag ttgaaaagtc gcttgtttta ccagtgatat agtcatccaa
    23881 accagcaaca gagtcctgca ctagatacaa agcttctgat tttttatcag ctgcatattg
    23941 caaacctgtc acaaaatcct gggcagttac aggcgcatat tcttctccct cagaagtaaa
    24001 ccacttggca tccttacgaa gtttgtaggt ataggtcaaa ccgtcctgag aaacagtcca
    24061 atcctctgct aatgatggaa taatattccc atattggtca ttttctaata acccgtctac
    24121 caaatttgca acaatatcgg atgttgctgc gcggttttct gctagatagt tcaaactaga
    24181 tggatcactt gaataaacat agttataggt ttttgatgca gtgctagaat ttccacacgc
    24241 gctcaataaa actcctgtac ccaggacaag acctgccaag gttagatatt tgctcttaga
    24301 ctttttcatt tccagaacct cctgctttaa atatttgttt tattatacaa ctctgggttt
    24361 gtttagtcaa ttgttttttc caaaaaatca aaaaaacctc attttctatt tttgaaagat
    24421 aattttagct attttgacgc taaaaaagga ataagtttca agttctccta aaagattgtt
    24481 caacttattc cttttattta taaatgctac cttacgaaag cttaaatttt gctcgcaggc
    24541 gatctgcttg ggcttttcct attaccttat ctaataaata ggtacgcaga ctcataacca
    24601 tataaagtcc accccccatg gcaccgacaa gagctacata aaagaagctc cacaaacgtc
    24661 cacttggttg gaagaaaaat cctaacagcc actggatggt tcctattaac agaaacatga
    24721 ctagggtcag caaactgatt aaaatggttc gcttcaaaat caccttgcgc ttgacaccag
    24781 ttactttaca aatatcccga tacatcaaga cgttaggaat gatgagagca atggttgttg
    24841 aaatcaaagg accataactg tggaagaggg cgatggtagg tagttgcaag actagcttgg
    24901 caatagaacc atagataaaa tagagaacgg ccttgcggtt gcggaacatg gcctgaagca
    24961 ttggagacaa gaccatgtac aagcctaaaa taatagactg caaaactgca aagacaaata
    25021 agcccagagc caaactatct ggcttaccat agaagaccgt ataaagaggt tctcctacca
    25081 taaccactcc aaccgttgct ggtagcaaga acataaagag tagggtgaga ctgtcctgaa
    25141 cgagacgaga agctgctttc aagtccccct tgacatagtt ttccgtcaaa agtggcaaac
    25201 caacactccc aatcgaaacc cctacagaaa tcaaaatcat cgtgatttta ttaggattgg
    25261 ctgagaaata agaaaacatg acaaccaagt cctcattgct gtagttggta aaccagctca
    25321 tactattgat aaaggtcagc tgatccaaaa tctggaagag ctggatggca gaccctgtca
    25381 ggataaaagg aatggcttcc ttaatggtat caaccaagag acgcttactg ttaatcttat
    25441 ctcctgtttc aaagactctt ttgagtgaac cttcttgggc aaggaaataa atcaagactg
    25501 caaaactggc taccataccg acaaaggcag caaaggttga ttgggtaacg gctgctagat
    25561 aatctcctga accgagcttc ataatgataa aggttgctag gagcatccag ataacacgaa
    25621 tgacctgctc agcaatttgg ctcatagcat agggtttgag gttattcatc ccttggaaaa
    25681 atcctcggat aacactcata gacgggaaaa tcaagactcc ccaagccaag ctttgcatga
    25741 ttgggatcaa gtctttgccc acgccagaca agtctgctag ccaaggagca aagacataca
    25801 agactaaagc aaaaaccagg cctagtcctg tcataaagcc taagaagctc cgaatcaggg
    25861 caaagctatg ctcttcttct cgcatggtat tatacttggc aacttgcttg gccaccgcaa
    25921 ctggaatccc cgctgttgaa accaacaaga accaagcata gatattgtaa cccatggtaa
    25981 agagaccatt tgccttagct gcataagccc ccatccagat gtaccaaggg ataatgtaaa
    26041 cagccccgag taggcgactg ataaagttac tagccgttag ccaagcagtc ccccgtaaca
    26101 tctgggcctg ctggtgattg ttttcgtgcg acatagattc ctcattcaat tttgataact
    26161 aggaaaaact ccttatcttc cattataaac ttttccttgt tacttgtaaa tttacgactt
    26221 tcggtttaca atagaaagta tgattaagat tgaaaccgta ttagatattt taaagaaaga
    26281 tggccttttt cgcgaaatta ttgaccaagg tcattaccac tacaactaca gcaaagttat
    26341 ttttgatagc atcagctacg acagccgaaa agtaacagaa gacactcttt tttttgcaaa
    26401 aggcgctgcc tttaaaaaag aataccttct ttctgctata acacaaggtt tagcttggta
    26461 tgtagctgaa aaggactacg aagtcgatat ccctgtcatc attgtgaacg atataaagaa
    26521 agccatgagt ttgattgcca tggagttcta tggtaatcca caagagaaac tcaaactcct
    26581 tgcctttact ggtactaagg gtaagacaac agcaacctat ttcgcctata acatcttatc
    26641 tcaagggcat agacctgcta tgttgtcgac catgaacaca actcttgatg gcgagacttt
    26701 ctttaagtca gcgttgacaa cccctgagag tattgacctc tttgacatga tgaatcaggc
    26761 tgtgcaaaat gaccgtaccc acctcatcat ggaagtctcc agtcaagcct atctagtcca
    26821 tcgagtctat ggactgacct ttgatgtagg agtctttctt aacatcactc ctgaccatat
    26881 cggcccgatt gaacacccta gctttgaaga ctatttctac cacaagcgtc tcttgatgga
    26941 aaatagccga gcagtcatca ttaacagtga catggaccac ttctcagtct tgaaagaaca
    27001 ggttgaagat caagaccatg atttctatgg tagccaattt gataaccaaa tcgagaattc
    27061 caaagccttt agcttttcag ctacgggtaa actcgctgga gattatgata tccaactcat
    27121 tggcaacttc aaccaagaaa atgcagttgc tgctggactt gcttgtctcc gtctcggagc
    27181 aagtcttgag gacatcaaaa aaggcatcgc tgcaacccgc gttcctggtc gtatggaagt
    27241 cctcactcag aaaaatggag ccaaggtctt catcgactat gcccacaatg gggatagtct
    27301 gaaaaaactc atcaatgtgg ttgaaactca tcaaaccgga aagattgctc tggttctggg
    27361 atcaacagga aacaagggag aaagtcgtcg taaggacttt ggcctcctcc tcaatcaaca
    27421 ccctgagatt caagtctttc tgactgctga tgaccctaac tatgaagacc ccatggccat
    27481 tgcagatgaa attagtagct acatcaatca tcctgttgaa aagattgcgg atcgccaaga
    27541 agccatcaag gcggcaatgg ctatcacaaa tcacgaatta gatgcagtta ttattgcggg
    27601 taagggagcc gattgttacc aaatcatcca gggcaagaaa gaatcctacc caggagatac
    27661 agccgtcgca gaaaattatt tataagaata gaaaaaatca agggaaaatg aaacccttga
    27721 ttttttccta ttatttagta aaaacgtttt tcaaaccttc aacggcacct tctacagcac
    27781 cttttgcgtc ttctacaacg tcttttgcct tagcaactgt tttttcaaca gctccttcaa
    27841 gttctgtctt gctgtctcca gtaactttac caaaaccttc tttgacagcg cctgttgctt
    27901 gttccaattt gttttcaagt gacatatgat tgtctccttt agtttattcc gatatgtgtt
    27961 accggttaca tatagtttat accgaatact aaggaaagtc aaacaatgtg ctcagaaaca
    28021 agaaatcacg ctaagtagaa agttaatctc tccttatcaa aatcgatagc caactcatac
    28081 tttctatctt cattttgcac aatatagcct aagacaacca aactgtccac aaagatatca
    28141 cggcatttct gcataagctg gtcttttttg agaaatttca acaaaaaagc cgtcatatac
    28201 ttgagtgcat actcaggatt aacatctcct aaaatgtcat agagctcctg ctgtttttct
    28261 gtcaaaggat actgctgttt gaccttgtaa aaataattgg acagggtcat tttaatgcgc
    28321 gcaaagtccg tctttcaact aaaatagctg cattgatttg attgcgcaat tccgtctcaa
    28381 aactctgctc caacaaggct tgatagaccg gactagcttc tctgacaaaa atctcttgat
    28441 ccagttcaag actatcaagt gattcaagcg taggaaaatt gaggtaatag cgcttatttt
    28501 cacgtagaat caagcttgcc tttatatact cttccatgag tttatcaact gcaacatctg
    28561 gaaattgagc cttaatttcc cgtagaatca catcctcata ctggtccaga tagcggatca
    28621 attctccaaa aatggctgtc tcgtcaaacg agatggatta aaaatctgaa tcatgaagat
    28681 tcctttcttt acattgtaac agaggcgatg ctgccaactg actaggattg gtcccagctt
    28741 ggttcagagg aacaggcaga cctagttcta tgtaatactc cctccaaaaa tcactaatct
    28801 cctgttcccc atctccaaat ttcataggaa tagtttcaaa aataggtagg atttctgcta
    28861 tatactggga gcagtagaaa ccagctgcat ctggatagaa agaagcattg tagggtgctc
    28921 caagatgtct gcaagttctt tccttcaccg actggatatc catttctggg taaacataga
    28981 ggtcgtacaa atgattggac tcaaagaagt ctgccggttc ttgacagaca acaccagcct
    29041 gtccactagc atgataaatc atcccatcca aataaatggc aacatggcta tagttacctg
    29101 tggaagtctg gatggcctgt cccatgtctg acccatctct cacaaaaatc aaatcgccat
    29161 tttctaacat acttcactcc tagaaaaaaa ggagccgaaa ctcctttcga tataaggcaa
    29221 actagacttt ccgattttga gctgacaccc aaaatcttac gcattaaagc tttcagttaa
    29281 ttgaggtacc acttgtttct tacgtgaaac ggcaccagca aggaaggcat gattgttttc
    29341 aagtttgaaa ttgaaagccg cttcgacctt gtccatattg gcaccaagag ccaatatttc
    29401 tgagtttgag ttgacgatat ctgtaatcat caagacaaag tcagagtagc cgtttgattc
    29461 gttggcagct tgcattgcag cttcaatttc tgcttggcgt tccaaaactt cagcgatgtc
    29521 aactgtgttc acttgggcaa cacggacatt atttccgttg agttcaaaag tcttagcatc
    29581 gatgtcaatc aattcttcag cagatttgct agccaagttg gtaccagctt tcaacattgc
    29641 caaaccatat tcttccaagt ttacaccagc caattcagcc aattcaggag caatgatttt
    29701 atctgttggg tgtgttgttg gtgatttcaa aagaagggta tctgaaatca aacctgaaag
    29761 catcaaacct gcaatctctt taggcacagc tacaccatgt tctttgaaca tacggtaaac
    29821 gattgaagac gctgatccaa ctggctccaa acgcatgtaa agtgggcttg cagtttcaaa
    29881 gttagccaca cggtggtggt ctacaacacc gtaaacttct acttcagcga tatctgatac
    29941 agattgttgg aattcattgt ggtcagtcaa gataacttgc tctgccccct ctgctttggc
    30001 agaagtgata acacgtggtg cttccacacc aaaatagttc aagacaaagg ctgtttcttc
    30061 atttggagtt ccaagggcaa cagcttccgt atccaaaccg taagcttctt ttgcaaggta
    30121 ggcaaaagct acagatgacc cgatggcatc tgagtctgga ttttggtgac caaatactag
    30181 aatcttggac atgataatac ctcattttgt ttattttctt tattgtagca tttttttcgc
    30241 tttttgacaa aggtaagagg agtcaaagga ctccccacga ttcttcaaaa taactgagta
    30301 aatttctatc ttgattttca gataaaaatt cttccttctg tggcctcttc ttacgcttga
    30361 aaagagcttc agccgacatg gcttcttcct tactggcaaa accttgagca tagataagtt
    30421 tgactggcaa gcgtgctcgt gtatatttgg ctcccttccc actattgtgg atagcgaggc
    30481 gtcttctcat atcagtcgta tagcctatat agtaggatcc atcacgacac tccagaacgt
    30541 acatataagc cttatgatcc ataataaatc tcttcgattt cgggcgtata agagccatca
    30601 tcattgtgga caatcaaagg aggtaagacc ttaaagccac ttgttgagcc atccttgatc
    30661 gcctcaatca aaagcatatt ggcttccttt tctctttttg gataaacaaa ctgcaggcgc
    30721 ttaggggcta gattatgtcg ttttaacgta tccaaaatat ccagaagtcg atcaggacga
    30781 tgaaccatgg ccaaacgccc attagacttg agaatactct gggcactatg acagatttct
    30841 tccaaattag tcgtgatttc gtgtcgagcc aagagataat gttcactctc gttcagatta
    30901 gaataaggat ccaccttgaa atagggtgga ttacacaaaa tcatatccac cttactcccc
    30961 tgaatgtgag caggcatatt tttcaaatca tcgcagatga cctgcatttg ctcctctaat
    31021 ccattcaaac ggacagagcg ttcagccata tccgccaaac gctcctgaat ctcaacagac
    31081 aatatctgtg cttgagtacg agtgctagca aaaagcccca ctgctccatt cccagcacag
    31141 aaatccacaa tcaacccctt cttaggaaaa cgtggaaatc gtgataagag aacactatcc
    31201 accgaatagc taaaaacctc tctattttga atgattttga tatctgtcga aaagagctgg
    31261 ttaatgcgct ctcctgattt taataattgt tcttcttcca tggtcctatt atagcaaatt
    31321 tatattaaca ttacaaacaa tataaaactc taaactactt cttctttttt aaatggtgca
    31381 gggcttctcc agtccagatt ggtagcattc gtcgaaaggg agcaaaaccg tagttaaagc
    31441 ggtcgcttga aaagcgtctc cgtctaggaa actggtactt ttcttcctcc aaagtgcgga
    31501 tagaaagact ggctttcccc gtaaattcat ctaaatccac tacctgaact tgaacctctt
    31561 catcgacttt caaggtttca tgaatatttt caataaatcc tgtccgaatt tctgaaatgt
    31621 gaatcagccc cgtatcaccc gtctctaact caacaaaggc accgtagggc tgaatccctg
    31681 taatacgccc ctttagctta tcaccgattt tcatcttagt cctcgatttc aatagtttca
    31741 attacaacat cttcaactgg cttgtccata gctcctgtct caacagcagc aatgacatcc
    31801 aagacagcgt aagatgcttc atcagctaac tgaccaaaaa ccgtgtgacg gcggtctagg
    31861 tgaggtgtcc caccttgatt ggcatagatt tctgcaatcg gttctggcca accaccacga
    31921 gtaatttctt tcttagaata aggtaggtgt tggttttgca cgataaagaa ctggctgccg
    31981 ttggtatttg gaccagcatt tgccatggaa agagcaccac ggatattgta aagctcttct
    32041 gagaattcat cctcaaaaga ttcgccgtag attgactcgc cacccatacc agttccagtt
    32101 gggtctccac cttggatcat aaagtccttg ataatacggt ggaaaatgac accatcatag
    32161 tagccatctt ttgaaagaga tacaaagtta gccactgttt taggagcatg ttcagggaaa
    32221 agcttgatac gtaagtctcc gtgattggtc ttaatagtcg caagaggacc ttctactgtt
    32281 tcaatgtcta cttgtggaaa atgcaattct ttttctacca taccaaatac ttctaaggca
    32341 tcaaaaatgc catcttcttc taatgttttt gtaatataat ctgctttttc tttgatttta
    32401 tcatgagaaa ttcccatggc aacgctgatt ccagcataat caaagagttc caagtcattg
    32461 agaccatctc caaaaaccat gaccttctct ggtttcaagc caaggtgttc cacaaccttt
    32521 tccacccccg tcgctttgga gcctgaaatc ggcacaatat cagacgaatg ttgatgccaa
    32581 cgaaccatgc gaagtttgtc tgagagactg tcaggcaagt gcaagtcatc tcccttatct
    32641 tcaaaagtcc acatctgata gatatcttct ttttcatgga aatcgggatc tacatctaag
    32701 tcgggataaa ttggattgat agcttcactc atcatatcgg tgcgagtcga caacttggca
    32761 tcatgactcc caaccaagcc atactcaatt ccttcttgct taacccaaga gatatactcc
    32821 tcaacatatg acttttcaat ctgatgctga taaatgacct gacctttttt atcttcgata
    32881 taagccccat tcaaagttac aaaaaagtca ggtttgagat cacgaatctc tggaacaaca
    32941 ccaaaaatgc cacgtccaga ggcgattcct gttaaaattc ctttttcacg caactgttta
    33001 aaaacagtgg gaattgtagt tggaataaac cctgtctttg aattccgcaa tgtatcatca
    33061 atatcaaaaa agacaatctt gatcttcttt gccttgtatc ttaatttcgc gtccatctca
    33121 ctacctcttt caatctaact ctttccatta tatcataaag taggcaaatc ccctattttc
    33181 aaaaagttta tcatttttat tttaatttct tggatgagaa aaaagacata tttatgaaaa
    33241 agctccatcg tgcttttaat gtgttctctt gttttcaaac tcgtaaaaag ggagccactg
    33301 agcctgactc gctctctcat ttcaaagctt gtgaaaaaag acccgttggg gtcttaattc
    33361 gctttcttgt tttcaagctc atgaaaaaga gatccaaccg ggtcttttct ttaatcttcg
    33421 tttacgaaag gcatcaaagc cattacgcga gcgcgtttga tagctgttgt tactttacgt
    33481 tggtttttag ctgaagttcc tgttacacga cgaggaagga ttttcccacg ttctgaaacg
    33541 aaacggctaa gaagctcagt atctttgtaa tcaacatatt caattttgtt tgctgcgatg
    33601 taatcaactt ttttacggcg tttgaatccg ccacgacgtt gttgagccat gttttttctc
    33661 ctttataagt ttagttgtcc attagaatgg taaatcatca tctgaaatat ccaatgggtt
    33721 tgttgctcca aatggatttt cattacgtga aaagtctggt actgaatttg taggtgctga
    33781 atagtttgca gttggtgcag agtaagctcc acctgtgtga ccctcacgca cactacggct
    33841 ttccaacatt tggaaattct cagccacgac ctctgtcacg tagacacgtt gtccttgctg
    33901 gttatcgtaa ctacgagtct ggatacgacc tgtcaccccg ataagtgagc cttttttagc
    33961 ccagttagca agattttcag cctgttggcg ccacataacg acattaataa aatcagcctc
    34021 acgttcacca ttttgactct taaatgtacg gtttactgca agagtaaaag tcgcaactgc
    34081 tacatttgat ggggtataac gcaactcagc gtcacgtgtc atacgcccta caagtacaac
    34141 attgttaatc atagtttacc ttcttacgcg tcaattttga cgatcatgtg acgaagaatg
    34201 tcagcgttga ttttggaaag acggtcaaac tctttaagag ctgcatcgtc atttgcttca
    34261 acgttaacga tgtggtaaag tccttcacgg aaatcttgga tttcgtatgc aagacgacgt
    34321 ttttcccaag tttttgattc aacaacagtt gcaccgttgt cagtcaaaat agagtcaaaa
    34381 cgtgctacca aagcgttttt agcttcttct tcaatgtttg gacgaatgat ataaagaatt
    34441 tcgtatttag ccattgatat gttcctcctt ttggtctaat gaccccaaga ctttgcaagg
    34501 ggtaagtgag gttcgctcac aataaactat tatactagaa aaaatttttt tacgcaagta
    34561 aaaacactag aattcgaaaa aacgccacat gggcgttttc ctgttcttat ggtttgatac
    34621 ggtgcaacat acgtgggaat ggaatagctt cacggatatg ttttgttcct gctgcgaagg
    34681 ttaccatacg ttcgataccg ataccaaatc ctccgtgtgg aactgtaccg tatttacgaa
    34741 ggtcaaggta gaattcatat tctgtacgat ccatgccaag ttcatccatc ttagcgacaa
    34801 gggcatcgta atcttcctca cgcatagacc caccgataat ttctccatag ccttctggag
    34861 caagcaagtc tgcacaaagc acgcgctctg gatttccagg aactggtttc atgtagaagg
    34921 ccttgatggc tgctggatag ttcatgacaa atgttggcac accaaagtgg tttgaaatcc
    34981 aagtttcgtg tggtgaccca aagtcatcac catgctcaag atgctcgtag tcagcatctt
    35041 catcattttc atgctcttgc aagaggtcaa tggcttgatc gtaagtgata cgtttgaatg
    35101 gctctgcaat gtagcgtttc aagagttctg tatcacgttc caaggtttcc aaggcttgag
    35161 gcgcgcggtc aagaacacct tgtagaagag ctttcacata agcttcttgc aagtcaagcg
    35221 actcatcatg tgtcaagtat gagtactcag catccatcat ccagaactca gtcaagtgac
    35281 ggcgtgtttt tgatttttca gcacggaaaa ctggaccaaa gtcaaagaca cgaccaagag
    35341 ccatagcccc tgcttctagg taaagctgac ctgattggct caagtaggct ggcgttccga
    35401 agtagtcagt ttcaaagagt tctgtagaat cttctgccgc atttcctgaa agaattgggc
    35461 tgtcaaactt cataaaaccg ttcttgtcaa agaactcata agttgcatag ataatagcgt
    35521 tacggatttg caacacagct acttgcttac gagagcgtag ccacaagtga cggttatcca
    35581 tcaaaaagtc tgttccgtgt tcttttggtg tgattgggta gtcttgagat tcaccgatca
    35641 cttcgatgtc tgtgatgtcc aactcatagc caaatttaga acgttcgtcc tctttgacaa
    35701 tacctgtcac ataaacagac gtttcttggc tcaagcgttt gataacatca aacttctcaa
    35761 gtcccacttc ttcaccaaat ttttcgacaa agtttggttt aaaagccaca ccttgaaaga
    35821 aggctgttcc atcacgcaat tgtaagaaag cgatttttcc ttttcctgat ttgttggcaa
    35881 cccaagcgcc aatcgtcact tcctgaccaa catagtcttt tacgtcaata atcgttacac
    35941 gttttgtcat tatttttcct tttctttttt attctttatg gcaaaccacc tctatattgt
    36001 tcccatccag gtcaatcata aaagcagcat agtaaatcgg atgctcactt cgataaccag
    36061 gaaccccatt gtctcgccca cctgcctcta tgccagcctc ataacaagcc tgaacttctt
    36121 ccttattttc tgctaaaaaa gcaaaatgaa caggatcttg tgttccctga gtcagccaaa
    36181 aatcaccacc aggatgaggg ctgttcgggg atagaaaact aattagagaa ctagtcttaa
    36241 aagccaattt atagtccaaa ggaacgagaa aactcctata aaatccttct gaaatttgta
    36301 aatcctttac cttaatctca aaatgatcaa tcattctcac tacccataaa tgctttcaag
    36361 cgttcgactg cttctttaag cgtgtctagg tctgtcgcat agctgaggcg gacattttct
    36421 ggtgctccaa atccagctcc tgttaccaag gccacttcgg cttcttctaa gataacagtt
    36481 gtaaagtctg tcacatccgt gtagcctttc atctccatgg cctttttgac atttgggaag
    36541 agatagaagg ccccttgtgg tttgaccact tcaaatcctg gcacctctgc aaggagggga
    36601 tagatggtat taagacgttc ctcaaaggcc tgacgcatgc tttctacagt atcttgctca
    36661 cctgatagag cctcaactgc tgcatattgg gctactgctg acggattcga agttgtttga
    36721 cctgcaatct tggacatggc agcgataatg tctgcttctc caacggcata accaatccgc
    36781 caaccagtca tggcataggt tttagacaca ccattgatga ccactgtttg cttgcgaatc
    36841 gcttccgata ggctagaaat cggtgtgaac tcatgaccat tataaaccaa gcggccatag
    36901 atatcatctg ctaggatgag aatatcattt tctacagccc agtttccaat tgccaagagt
    36961 tcctcacggg tgtaaatcat acctgtggga ttagatggcg aattcagcac caaaaccttg
    37021 gtcttgtcag tgcgagctgc ttctaactgc tctacggtca ccttaaagtg attgtcttcc
    37081 ttagcagaaa caaagacggg aacgccttct gccatcttga cctgatctcc atagctaacc
    37141 cagtatgggg ttgggatgat gacttcatca cctggattga ccacagccat aaagaagcta
    37201 tagagagaat atttggctcc cgcagcgact gtcacttgat ttgacgctac agaatagccg
    37261 taaaagcgct caaagtagct attgaccacc gccttaagct ctggcagacc tgaggttact
    37321 gtataaaaag aagcacgccc atctcgaatc gatgcaatgg cggcatcttg gatatttttg
    37381 ggagtagtga aatctggctc acccaaggtt agagacaaaa tatctctacc ctcagccttc
    37441 agtgctttgg cacgggctcc agcagccaaa gtcacacttt cttccatttc taaaacacgg
    37501 ttggatagtt tcataggccc tccttgttga ccaatgctcc tgtttcaaaa tctactagat
    37561 aaaaatcaga tcctgactta acttcccaga ttggcttatc ttgataacgg ccaaaggtta
    37621 tcttgtcaat ctcgccagct cccttttcct tagaaaccgt ttctgctttt tcttgtgaaa
    37681 caccctgatt tagctgataa acgtaaatct tatggtcatc tttaccaatc aggacagcaa
    37741 gcgcttcttg ctgtttgtta cgaccaagaa cgctgtaata agattccaag ccattgtata
    37801 aatcaacctg atcagcctgc tctaatcctg catactgctg agctaatttt tctccttcac
    37861 ttttagctgt ttgatagggt ttcatactaa gagaaaccat atacagaaag gaaccactga
    37921 taaccacaaa caaaatcgtc atccctagac catactgcca cagtagatta ttttttgctt
    37981 tgttttgtct ttttttcact cgtctatttt accatctatt aagctttatt acaagtgaat
    38041 ataagaatac tcttcgaaaa tctcttcaaa ccacgtcagc tttatctgca acctcaaagc
    38101 tgtgctttga gcaaccaatt ctatttctcc cttcaaacaa aaccgatttt gaaagtgaaa
    38161 cagttcttac tttttcagtc acaaatgatt agagtttccg aaattttaca attttcaaat
    38221 aaactctgag caaatttctt gcaagttctt ttgttttgtt gtaatatatt ttataacaac
    38281 gagagagttc tcgaaatttt aagaaaaagg agacacatca tgtctaaaaa agtattattt
    38341 atcgtcggat cactacgtca aggttctttc aaccaccaaa tggcgctcga agctgagaaa
    38401 gcacttgctg gtaaagtgga agttagctac cttgattatt cagcccttcc tctcttcagc
    38461 caagatttgg aagttccaac acatccagct gtagctgctg ctcgtgaagc agttctcgtt
    38521 gcggatgcta tctggatttt ctctccagtc tacaacttct ctatccctgg tacagtgaaa
    38581 aacttgcttg actggctatc tcgtgccctt gacttgtctg atacacgtgg cgtttctgcc
    38641 cttcaagaca agtttgtcac agtatcatct gtagccaatg cagggcacga tcaacttttc
    38701 gctatctaca aagacctctt gccatttatc cgtacacaag gcgttggtga tttcactgct
    38761 gcacgtgtta atgactctgc ctgggcagac ggaaaattgg ttcttgaaga aacagtccta
    38821 aactcacttg aaaaacaagc tcaagacttg gtcgaagcga ttcagtaaaa aatagaaaat
    38881 tttagaaagt ctaaatcaat tatagccacc taatagggtg gctttttatt tctcaatcaa
    38941 gattttcaga caaacatcag ccatccaaaa aaaaccttga gcgttaccac tcaaggtttt
    39001 tagcagtctt ttccatcata ggaaaatcat tctaagaata ttctttcatt cgagatctat
    39061 cacttatcat cttctttcga gaaattagtg actgcttttg gctgattaat cttcttttct
    39121 tcgtcctaca tataggctca atagaatacc gctacctaaa agaacagaga tataatcaga
    39181 ttggcttcca gtttcaggta atttgtcccc acggttttct ttacctgtag ttggtgctac
    39241 tgggttagca tttactggag ttgctggttg agccggtgtt ggtactactg gttgttctgg
    39301 aaccgctggt actggtttaa ccggtacttc tggtgttgaa acagctggag ttggttgtac
    39361 tggcacttct ggtgtcggta catttggtgt tggttgcgct ggcacaggtt taaccggtac
    39421 ttctggtgtc ggcacatttg gtgttggagg aactggtttg tcttggcatc cacattttcc
    39481 atctttaccg tctttaatca ccatttctgt cttacttcca tctggattag tgattgtaac
    39541 aacgtgagtt ccatcgttat tatttttaac agttacagtt ggtgaaacgc tatctttgcc
    39601 gtctttacca tctttgataa tagatttgta ttcacgacca tcagaatcta cgattgttaa
    39661 tgtatgagtt ccatctccgt tatcaacgat gttcgctttt ggtgatttac catcaaagat
    39721 tgtagttgtc gttcctttac catcagcacc tgtcacttta atagtgtgtg aaccatcgtt
    39781 gttatcaata acttcaagtt ttggttctct accatcacga actgtagttg ttgtagttgt
    39841 tccgtctgag ttcacaactg tgatagtgtg agttccatct ccattatcca caaccttagc
    39901 agttggtgat ttaccgtcac gaactgtggt ttcagaaaca gtaccattac cgttttccac
    39961 acgaatagtg taagtaccat cttggttatc tctaactgtt gctactggtg atttaccatc
    40021 tttaatgatt gtttcagtag ttgttccgtc accatttaga acagagatct tatgagttcc
    40081 attttgttca tcagttatag tcacttttgg tgatttacca tcacgaactg tggtttcagt
    40141 tgtcacacct tctggatttg taataacgat tgtatgactt ccgtctccat tatcacgaac
    40201 agatgcggtt ggagtacgtc cgtcaacacc gtcacgtcca ttcttaacaa caaactcatt
    40261 cttagttccg tctgggttag tgattgttac tgtgtggctt ccatctggat tttcagtagt
    40321 tgttgctgtt gcagctttac cgtctttacc atctttgatg atagcgttgg taacattgcc
    40381 gtctccatct gtaactttaa cagtatgagt tccatcgttg ttatccgtta cttcaacttt
    40441 aggagtctta ccgtctttac cgtttttaac aacagtttct ttagttgaac catctggatt
    40501 tgtcaccgta attgtgtggc ttccatctgg gttttctgtt gtagtgatat tcgcagtttt
    40561 accgtcttta ccatctttaa caactgttgt tgattcagaa ccatctgggt tttgaactgt
    40621 gatagtgtga gttccatctc cattatcttt tgtagtaata gttggagctg aaccatcacg
    40681 tccatctata ccgttataaa tatctttact atttaatact ttatcgacac cttcgtcgta
    40741 taccccattg tcattaacat catcataaac tgtaacacgg ataccgttac gcgttggagt
    40801 tgcagcagca tctgtatcgc gtctaattct tgaaggtgaa gtaatatctt ctactttgat
    40861 tttcggtgca cggccatctt taccattctt accatctttt acagtgaagg ttactggatc
    40921 tttacctgat gttgtgatag ttacaacagt gctttggcca tcttgtccac gttgagtagt
    40981 gattgtagga gtttgtccat cctgaccggt tgcaccagtt tctcccttag caccatcttg
    41041 aacaaagact gtagttggtt gtgaaccatc atggttatca acagtgattt ctacaccttt
    41101 atgccctgct tcatctttac gaacagctgt aactgtaggt gattttccat ctactccatc
    41161 tctaattacc gcaagtggtt tttctggatt taatggttgt cctgggttag ctggatcttc
    41221 ttggtaaact ttagtttctt taccatcctt gacagtaagc aatgatttac catctcgtcc
    41281 gtccgcgcct ttagcaccat ctttaatcat ttctgaacct agaagttcat cagttcctgg
    41341 tgtatatttg ccgtcattgt tttcatctgt atagaatgtc acaattgtat gagatggatt
    41401 tccgtttttt ccttggacac gaagtaaatc aacttttgga gttttaccgt tcagaccatt
    41461 ttctccgtcc ttaacattta ctgtaactgg atctttacct ggaacagtga atgtaatgtc
    41521 agtactatgg ccatctttac ctggagttac agttacttct ggagtcttac catcttctcc
    41581 gcgttcacct ttgtcaccct tagagccttt gatgttgccc tctttatccc agttgccgtt
    41641 attcttaacg aagacgtcgc ctgtttctgt attaacgtat ttatcgccgt ctttaccttg
    41701 atttgcttct ggattaactt tgccgttcaa cacgtcttta ccgtcacgtc catcacgtcc
    41761 atcacgtccg tcacgacctg ctgctccatc cgcaccttta gctccttgcg ctccagtcag
    41821 gccgcgttcg cctcggtctc ctttttcgcc tttagcacca tctgcacctt tgtcaccttt
    41881 agggcctttg atgttgccct ctttatccca gttgccgtta ttcttaacga agacgtcgcc
    41941 tgtttctgta ttaacgtatt tatcgccgtc tttaccttga tgtgcttctg ggttagcttt
    42001 gccgttcaac acgtctttac cgtcacgtcc atcacgacct actgcgccat ccgcaccttt
    42061 agctccttgc gctccagtta ggccgcgttc gccttggtct cctttttcgc ctttagcacc
    42121 atctgcacct ttgtcacctt tagggccttt gatgttgcct tctttatccc agtttccatt
    42181 gtttttaaca tagacatcac cggtttcggt attaatatat ttatctccat ttttaccttg
    42241 gtttggttgt ggatttactt ttccgtttaa tacatcttta ccatcacgac ctgcttgtcc
    42301 tgtagctcca tcacggatcg tagttgtcac atctggactt cctggattat gaaccgttaa
    42361 tgtatgtgtg ccgttttgcc cctcagttat tgttactgtt ggagttttcc catcagcacc
    42421 cttttgtcca tcctctacaa atgttgtttg tggacgacct tctactggtg taattgttac
    42481 taatacacca tttttgccat tttgcacact tcgtgtcgct gtaattgttg gtgattgtcc
    42541 attagtaccg tttcttccat cagtgatagt tgctaatggt tggtttggat taagtggttg
    42601 tcctggtcta gccggatcct ctacatagac ttttgtttca gttccatttt taacagcaat
    42661 tagagatttt ccatctttac ctggagttcc tggattacct tgttctcctt ttggtccttg
    42721 tggtcccgct ggtcctcttt gtccatctgc tccttttggt cctgctggtc cttgtgcccc
    42781 agttgcacct gttggccctc tttctccatc tttaatatct gtatttaaaa ttacttcatc
    42841 ttgattatta aagacaccat caccatcttt atctaaataa aatttaatgt gattcgtatc
    42901 ccctgtttta ttttgagttg cagcaatttt accaataccg tatttcatta cacgaggttt
    42961 agcagctgta actgtagtag cattccctac aggaagtcct aaaacatact gatctccaaa
    43021 tttatgaagt ctgtatgctt gtgatttctc tccttctacc ccttcagaaa ctaactccgt
    43081 tactccttct gctaatttag tagttggtat atataaagtt tggaaatcaa ctttagtatt
    43141 aaaacttgtt gttaaaggat tagcttgatt tggatttgca tctagataca atggatccgt
    43201 ttcaaaataa tagttagaat tactatatgg atcattacta gtcccagttc cactaccacc
    43261 ttggtctacg ttaaattcaa ctggacgtaa acgaagagat aaatctccgt tagggttagt
    43321 tataggtaaa ctaaacgtaa ttgtttgact tttgtttgtt tctactgcag cttctaaact
    43381 gtagcctgaa tgagaaacaa agtttccacc cttactaatg tttttaactt ggtttcttaa
    43441 gtttggtgtt ataacagtag caggtgtagg ttcaccataa cctgttccct tatctaagat
    43501 aaagttgtta ttaacaaact ctctaagatt tcctggcgca aaataattaa ttgtaaagtt
    43561 aatattattg cctctacgta ctgtcgttac atcataatgg atttcacgac caccacgtga
    43621 atgtcctata ccacgaaatg aatgtgagcc ctgactgatg tcagaaaatg caatagtatt
    43681 atttggattt aagattggtt tattttctgg tccagctgct ctaaaaccac ttcctgctgt
    43741 tctaaaacca ctataccccc tatcaacatc ttccttacgg atagctggat tttggcgagc
    43801 atcagaaagg ctcaaacctg gtttcaagat ttcattagta gatgctggag ctgaagttgt
    43861 ttctacttta gcagctgtgc tagttggcaa aacagcgcta tcaacagctg aacgatcagt
    43921 tgttgcagct ggattagtct cttccttcgc ttcaactata ttagctttct ttgctacagg
    43981 cgtttctgat acagttcctt tgttagagtt agaacgaagt tctagaccaa taatagatga
    44041 ttgaatagat gactctgctg ctgataattc agcttcagat gcatctgctt tcccaagcaa
    44101 gctttgacca gcttggatac ttgtttgcaa gttagcagca cttgcttctg tatataactt
    44161 gctttctaac tttttagcac gcgaaagagc cgttaacaat tttgacttgt caatagcatc
    44221 ttgatgcgtt acttcctctt ttttgtcttt tgcttcttca actttttctg ctggtttagt
    44281 aacttctcca gttttaactg gagtcgtttc tactggatta gctacagttg gagctgcata
    44341 ggttttctct ttattagacg cagaaacctc tgctggttta gtagctgctt ctcccctacc
    44401 aacagaaata ctattggtag tttcttgttt gttttcttcc gcttgtactg tttggacact
    44461 agctgctgca cctaatacca aagcggtacc gagcaagaca ctaactgcac caaagtaata
    44521 cttacgaata gaataacgtt gttgcatgct ataccagtca aatgattttt tatgtgaatg
    44581 tttcatttta aactcctaga tagtatttta tagtttacaa tgtacaacta tttgagacat
    44641 taatcaatat tttctgaaca attaatatat tctgtttttg cacttaaaag ccacttatat
    44701 tattctaatt tttccgatta ctaacgacaa ttttcttgct ctaatttttt tatactactt
    44761 agacaaaaaa agatataatg aattatggag gaaatacccg tatgagaaac cttttatcca
    44821 caaaagttca aagacaatta cgcttaatgg aaaccctaat tcagaatcgt aattggatga
    44881 aattacatga actagccgaa aaattaggat gtacagaacg aatcttaaaa agtgatttaa
    44941 atgaattacg tattgccttt ccatctatta acatccaatc ttctgttaac ggaatcatga
    45001 tagatttaga agttaacact agtgtagaag atatttatca atattttctt gctaattctc
    45061 aatcttttca attactagag tatatgttct tcaatgaggg gctacctatt tatcgaacaa
    45121 tagaaaatct ttactttagt agtgccaacc tctatcgact gggcagaaat attacaaagg
    45181 ttctttcatc tcagtttcaa attgaattat cttttactcc atccgagata cgtggaaatg
    45241 agatcgatat tcgttacttt tttgcccaat acttttctga gcgctatcat ttcctagatt
    45301 ggccttttcc tgaccttcct gaggaagatt taacagagtt tgctgacttc ttctataaaa
    45361 tcacgaatta tccaatgcga ttttcaattt atagaatgta caaactgatg atagctatca
    45421 gtatccacag ggttaaaaat ggtcacttca ttgacctccc caaccacttt tacaaagaat
    45481 attatcctct tttaaagagc attccaaatt tccaggagac acttgcttat ttctctaaac
    45541 attttgggct tgaaatgact ccagatacaa tcgctcaaat ttttatttct tttcttcaga
    45601 atgatatttt cctagatcct caagaattct tcaactcttt agaagataac agtcaagcaa
    45661 gatactctta ccaattactt agtcaaatat tagaacgcct atcaaaacaa tataagatta
    45721 cttttactaa ccacgatgag ctgatttggc atttacacaa cactgctttc tttgaaagac
    45781 aggaaatctt ttctacccca atcttatttg aacaaaaagc attgacgatt aaaaaatttg
    45841 aagtttactt cccagacttt atgggaagtg cgcgtcaaga actggctcaa taccgtcagg
    45901 caattggaca gcatgaccat cctgaacagt tggaacactt gatgtacacc atcttaaccc
    45961 atgctgaaaa cctctctact cagttgttag aaaatcgacc acctatcaag gttttgatta
    46021 tcagtaactt tgaccatgct atatccctta cctttgttga tatgctttcc tattactgta
    46081 ataaccgctt taccttcgat atttgggatg aattaaaaac aagtcctgag attttaaatc
    46141 agacagatta cgatatcatc gtgtctaatt tctatatttc agggattacc aagaagttta
    46201 tttgccgaaa tcatctgtca atcatgaatt tggttaatca tcttaacacc ttatcaaatg
    46261 agattcattt gtccaatact ttataagtta tcaaaaaagt cagcataatc gtgctgactt
    46321 ttctcttatc tgatttctat acttccttta caaaaaccaa tccctgtggt tgtgacaaat
    46381 cttctcggta aacaaatcca gcaaagttca agcgacgtgc ttcccccaca gtttgtactt
    46441 gattttctat taaagctgtt agaaaggccc cgcgcgcttt cttggagata gttgagtgaa
    46501 tcttcagctg accgcctcta tcctccatga atttgaaggt caccatcttt gctctgattt
    46561 ccttagaaaa tacagtctca aactctgatg acaagagaga gaaaatcact tcttccttct
    46621 tcagagcttc atcatagact gccttccaat ggctcttcaa agtcttacca gcgactttta
    46681 atttcatcaa aaaatccaaa cggtgaggag ccatgggtga caaggctgga acaacaccgt
    46741 acaaagccga ggtaatgaag acatgatttt caagataatc ttgttccgcc tcggtcagct
    46801 tatctctctt aatgttgcgg tacataagcc catcaaaaag tttcaaggct ggatagtgtt
    46861 gagcagtttg ccttttcaaa gcttggatat tttgaaattc ttccgccgct ttctcagctg
    46921 ataccttgta gaaactctcc aattgactgg cagaatagag agccaaggca tcaagcacgg
    46981 tctgactttc tggttttaaa ggaattgcct cgatacttgg caagtctgtg ttcatttctt
    47041 ttgctgttgg gattaaaatt ttcatattga tagtgtagca tattttttag ccacaaccaa
    47101 gaaattcatt tgaaaaa
//
LOCUS       DAVKXA010000010        46772 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKXA010000010 DAVKXA010000000
VERSION     DAVKXA010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.010"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(1..297)
                     /locus_tag="VW883_000601"
     CDS             complement(1..297)
                     /locus_tag="VW883_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273781.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VW883_000602"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VW883_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0273782.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3570..4796)
                     /locus_tag="VW883_000603"
     CDS             complement(3570..4796)
                     /locus_tag="VW883_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0273783.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4839..5531)
                     /locus_tag="VW883_000604"
     CDS             complement(4839..5531)
                     /locus_tag="VW883_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0273784.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5704..7455)
                     /locus_tag="VW883_000605"
     CDS             complement(5704..7455)
                     /locus_tag="VW883_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273785.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHLCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7445..9190)
                     /locus_tag="VW883_000606"
     CDS             complement(7445..9190)
                     /locus_tag="VW883_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0273786.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLFLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9396..9692)
                     /locus_tag="VW883_000607"
     CDS             complement(9396..9692)
                     /locus_tag="VW883_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0273787.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9711..9848)
                     /locus_tag="VW883_000608"
     CDS             complement(9711..9848)
                     /locus_tag="VW883_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273788.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNIA
                     P"
     gene            complement(9845..10300)
                     /locus_tag="VW883_000609"
                     /pseudo
     CDS             complement(9845..10300)
                     /locus_tag="VW883_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10434..11261
                     /gene="xth"
                     /locus_tag="VW883_000610"
     CDS             10434..11261
                     /gene="xth"
                     /locus_tag="VW883_000610"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0273789.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAKLDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11273..11416
                     /locus_tag="VW883_000611"
     CDS             11273..11416
                     /locus_tag="VW883_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0273790.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11527..11655
                     /locus_tag="VW883_000612"
     CDS             11527..11655
                     /locus_tag="VW883_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV0273791.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHEFAVLDPNGYFLRFSE"
     regulatory      12038..12133
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12533..13114
                     /locus_tag="VW883_000613"
     CDS             12533..13114
                     /locus_tag="VW883_000613"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0273792.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13114..14376
                     /locus_tag="VW883_000614"
     CDS             13114..14376
                     /locus_tag="VW883_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0273793.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLMMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14427..14888)
                     /locus_tag="VW883_000615"
     CDS             complement(14427..14888)
                     /locus_tag="VW883_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV0273794.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14885..15649)
                     /locus_tag="VW883_000616"
     CDS             complement(14885..15649)
                     /locus_tag="VW883_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV0273795.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15830..16234)
                     /locus_tag="VW883_000617"
     CDS             complement(15830..16234)
                     /locus_tag="VW883_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0273796.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16304..17785)
                     /locus_tag="VW883_000618"
     CDS             complement(16304..17785)
                     /locus_tag="VW883_000618"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0273797.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(17804..18982)
                     /locus_tag="VW883_000619"
     CDS             complement(17804..18982)
                     /locus_tag="VW883_000619"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0273798.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKREDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19146..20153
                     /gene="galR"
                     /locus_tag="VW883_000620"
     CDS             19146..20153
                     /gene="galR"
                     /locus_tag="VW883_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0273799.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLNQ
                     E"
     gene            complement(20200..21237)
                     /locus_tag="VW883_000621"
     CDS             complement(20200..21237)
                     /locus_tag="VW883_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0273800.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRSCVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21238..21591)
                     /locus_tag="VW883_000622"
     CDS             complement(21238..21591)
                     /locus_tag="VW883_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0273801.1"
                     /translation="MNIKSASDLLGISADTIRYYERIGLVPPITRTATGIRDFQVQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21835..22725)
                     /locus_tag="VW883_000623"
     CDS             complement(21835..22725)
                     /locus_tag="VW883_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0273802.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVIAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22858..23394
                     /locus_tag="VW883_000624"
     CDS             22858..23394
                     /locus_tag="VW883_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0273803.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTENYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23561..24367)
                     /locus_tag="VW883_000625"
     CDS             complement(23561..24367)
                     /locus_tag="VW883_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0273804.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24712..26232)
                     /locus_tag="VW883_000626"
     CDS             complement(24712..26232)
                     /locus_tag="VW883_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0273805.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26225..26953)
                     /locus_tag="VW883_000627"
     CDS             complement(26225..26953)
                     /locus_tag="VW883_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273806.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(26968..27732)
                     /locus_tag="VW883_000628"
     CDS             complement(26968..27732)
                     /locus_tag="VW883_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0273807.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27736..28179)
                     /locus_tag="VW883_000629"
     CDS             complement(27736..28179)
                     /locus_tag="VW883_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0273808.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28861..29157)
                     /locus_tag="VW883_000630"
     CDS             complement(28861..29157)
                     /locus_tag="VW883_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0273809.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29179..30243)
                     /gene="pepA"
                     /locus_tag="VW883_000631"
     CDS             complement(29179..30243)
                     /gene="pepA"
                     /locus_tag="VW883_000631"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0273810.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPEMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30644..31345
                     /gene="galE"
                     /locus_tag="VW883_000632"
     CDS             30644..31345
                     /gene="galE"
                     /locus_tag="VW883_000632"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0273811.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVG
                     SRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTVSLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31768..32727
                     /locus_tag="VW883_000633"
     CDS             31768..32727
                     /locus_tag="VW883_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0273812.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32717..33673
                     /locus_tag="VW883_000634"
     CDS             32717..33673
                     /locus_tag="VW883_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0273813.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            33670..34422
                     /locus_tag="VW883_000635"
     CDS             33670..34422
                     /locus_tag="VW883_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0273814.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34518..35483
                     /locus_tag="VW883_000636"
     CDS             34518..35483
                     /locus_tag="VW883_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0273815.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35708..35950)
                     /gene="yidD"
                     /locus_tag="VW883_000637"
     CDS             complement(35708..35950)
                     /gene="yidD"
                     /locus_tag="VW883_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0273816.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35950..36672)
                     /locus_tag="VW883_000638"
     CDS             complement(35950..36672)
                     /locus_tag="VW883_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0273817.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36659..37228)
                     /locus_tag="VW883_000639"
     CDS             complement(36659..37228)
                     /locus_tag="VW883_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0273818.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37247..37975)
                     /locus_tag="VW883_000640"
     CDS             complement(37247..37975)
                     /locus_tag="VW883_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0273819.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37975..38715)
                     /gene="xerD"
                     /locus_tag="VW883_000641"
     CDS             complement(37975..38715)
                     /gene="xerD"
                     /locus_tag="VW883_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0273820.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISVQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38706..39167)
                     /locus_tag="VW883_000642"
     CDS             complement(38706..39167)
                     /locus_tag="VW883_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0273821.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKTVNALLHDFSKEYEIRCQ"
     gene            complement(39164..39685)
                     /locus_tag="VW883_000643"
     CDS             complement(39164..39685)
                     /locus_tag="VW883_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0273822.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39661..40632)
                     /locus_tag="VW883_000644"
     CDS             complement(39661..40632)
                     /locus_tag="VW883_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0273823.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40629..41423)
                     /gene="racE"
                     /locus_tag="VW883_000645"
     CDS             complement(40629..41423)
                     /gene="racE"
                     /locus_tag="VW883_000645"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0273824.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41630..41878)
                     /locus_tag="VW883_000646"
     CDS             complement(41630..41878)
                     /locus_tag="VW883_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0273825.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42020..43645)
                     /gene="treC"
                     /locus_tag="VW883_000647"
     CDS             complement(42020..43645)
                     /gene="treC"
                     /locus_tag="VW883_000647"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0273826.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43823..45790)
                     /gene="treP"
                     /locus_tag="VW883_000648"
     CDS             complement(43823..45790)
                     /gene="treP"
                     /locus_tag="VW883_000648"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0273827.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            45975..46685
                     /gene="treR"
                     /locus_tag="VW883_000649"
     CDS             45975..46685
                     /gene="treR"
                     /locus_tag="VW883_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0273828.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        13689 a        10642 c         8746 g        13695 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttacca ccgaatatac
      841 tattctctga cactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc tactgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatactatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttaac tgtcccgatc
     2701 aatttgtcct attcttattt cattttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttattgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttacctgaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatgggat attcgtatta ttataatatc aacatgctat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaag acgcgagttt ccacaatctc actcatggaa actcacgtct
     3301 ttcaaaaaat agggtgaatt gaaaactaga acaagacact agattttcta aatgatgtct
     3361 agtaaggatt ctaaatgcta caccaaattg ctcacatctt atttcaaacc acgggactcc
     3421 cacaagaaag gaaaatccta taaaaattct ctctctgagg agaaagaggc ctcaactaca
     3481 ggtgtaaact attatcaatt gaaaacaaca gtttttacac tcaattagac tttttaggga
     3541 caggatcact ttcgcttgac tgtagtttgt catttttttg ataaagttag cactttttca
     3601 gaaactgttt tgaaagtctc aatgatatag tctacttctt catcgcttaa tttagtatga
     3661 agagggaggg taatttcatt ctcaaagaag gcataggcct taggatagtt cgtcatatca
     3721 aatccaagat tcttataggc tgtcaagaga ggaagcggtt tgtagtgaac attacttgca
     3781 attcctgctt tagccaattc ttggatgatg aggttgcgtt cttctaggct tgctccttct
     3841 acacgggtga tgtagaggtg gcgtgaagat tcgacagttt cagtcttgtg tgccaaagga
     3901 tggatgcgag aacctgcaaa accactatca tagcggtcca caatgtcctt acggcgttgc
     3961 aacaaacttg gatagcggtc caattgtacc aaaccaagtg aagccatgat atcggtcatg
     4021 ttgcacttat aggctggtgt aacgatatcg tattcccatg accccagttg catcttggca
     4081 agagcatcct tagtttgccc gtgaagggaa aggatttgga attccttgta catctcttcg
     4141 tcatcaatca ctggattggc tttccaagtc gcacttccac cttctgccgt tgtaaagttc
     4201 ttaacggcat ggaatgagaa ggaagtaaaa tcagcgatag aaccagaagg ttgtccttta
     4261 taagtagatc ccaaagcgtg ggcactatca gagacaatga caatacggtt aaaggccttt
     4321 tgccacttgc ttgaagcggt aaagaagtca cgttttttct ccacgacttg gaacaaacgg
     4381 tcataatcgc aaacaatccc tgcgagctct actgggataa tcaccttagt tttctcagtg
     4441 atagcttgct caagcaggtc atagtccatc tcaaacgtat ctgcttggat atccaccatg
     4501 acaggggttg ctcccacgtg cgtaatgaca ctacatgaag ccgtataggt catggctgga
     4561 acgatgactt catcaccagg tcccacttcc aaaacgcgta aaatcaactc cagagcggct
     4621 gtcgcagagt tgagacaaac agtcttaggt gtctgtgtgt aaagagacaa gcggcgctcc
     4681 agttcttttg ttttaggacc tgttgtgatc caaccagaac gcagggtatc cgctacttca
     4741 gcaatttctg cttctgtgat atcaggcggt gaaaatggaa tattgtaatt tggcattgat
     4801 ttgctccttt tatctgtact cattttctta tgactacttt attttagtac ctcaaacacg
     4861 gtttgaaaca tgattttgat gtccccaaag aaactaaact ctcggagata ggcgaggtta
     4921 tagcgcatct tttcaggaag aacatgctcc acataggcct gatcaactga cagacctttc
     4981 tccgtcattt gactgatgat ggtgtcctca tccttgtagt tgatgctggc tggagaggta
     5041 attcctgctt gcaagagcaa ggttgccatc atttcagggc tatactgctc tgtataacgt
     5101 ggcacttcag gtcgtgtacc gacaaaggac atctcacctt taaggacatt gaccaactga
     5161 ggcagttcgt ccaaacggac acgtcggatg aaatttccaa ccttggtaat acggctatcg
     5221 ttagcagaag tcaccagact tcctttttta tccgcatccg tcaccatggt acggaacttc
     5281 caaatcttga accgacggtt gtactgggtc acacgctctt gcttgtaaat cactggccct
     5341 ttgctatcca acttgatcca aatgctcaag atgagaaaga tgggagaagt tagaaccagt
     5401 aagaccaagg ccaaaaccca gtccaagcaa cgcttgaaaa tcagcgaacc cttcctttta
     5461 gagacaagct ggtagtaaga ctcaacctcg cttgatttca tttccacagg caagtcttcc
     5521 catttcagca tgctgttctc ctttgttttt attatactat ttgtcaacat ttttcattat
     5581 accacaaaat ggaaaaggcg gtgaaagaaa tctgtaattt gaaggatttc cttctagtac
     5641 tcaatgaaaa tcaaagtaca gctttgagat tgcagataaa gctgacatgg tttaaagaga
     5701 ttttcaaaga gtataggcca tggcccctgc ctgcaaacta tacatcttgt gataggttcc
     5761 tcccagagtc aagagttcct catgggttcc actctcgata atgcgtccct tatccaagac
     5821 atagatgcag ttggcgtctt gaatagtaga aaggcggtga gcgatagcaa tagttgttcg
     5881 gccctgtctc atcttcgcca gagaagcttg aaccaaactt tctgtttcag agtcaatatt
     5941 ggctgtcgct tcatccaaaa tcaggatttt aggctggctg gcgactgttc tagcaaaggc
     6001 aagaagctgg cgctgcccag tagagaagct cgaaccacgc tcggaaacag gggagtcgta
     6061 cccctgagga agttcttgaa taaaggaatc tgcatccaca aaggctgccg cagcctgaac
     6121 ctgctcatca ctgatttctt ggtacatggc gatattggac ttaatagttc catgatagag
     6181 gaagggttcc tgtaaaacca aaccgatgtt ttttctcagc tcttcttgac tgaaatccct
     6241 gatatccaca tcatccaaga gaactctccc tgactggaat tcataaaagc gcatgaggac
     6301 attgataata gacgatttcc ctgaacctgt atgacctaca aaggcaatgg tttcaccctt
     6361 attaacagag aaagaaatgt catccagaat cggatgttta ccgtcatacg agaaacacag
     6421 atgttcaaaa cggatattgc cttctttgac tttggcttgc ccattttctt gaaggggctc
     6481 ataggtcctc tcatcgatta aggcaaagac acggcctgca gaaaccatag acgtttgcag
     6541 tgttgaaaag ttttgcgtca cctcaatcaa agggtcaaag aggcggttga tgtactggat
     6601 aaaagcatac atggtcccgg ccgttatccc gatagaaaga ccacgatagc caaaataggt
     6661 catcaagaca gcataaccta gaagtttcaa caaactcatg gcaggtctca aaaagagggc
     6721 atccaaggct acagaacggt tggcataggc caagtgctct tggttgattt catcaaattc
     6781 tgcctgcagg cgcttctctt gattaaaagc ctgaataatc ctgattccct cgatattctc
     6841 tgccagctta ctattgatat ctgacaagag acttctggtt ttctcgatga ttttcactga
     6901 cttttttcga tagagattga ccaaaaggaa aatcaagggg agaaagagca agactaatgc
     6961 tgtcaaacga aaatccagca ccaacatggt ataaagggtt gtcagaaaga taaaaactgc
     7021 tgagataaag ctggataaaa tcccagaaaa catatcacta atcgtctcgg tatcgttggt
     7081 caaacgagaa acgatagaac ctgctggcgt cttgtcaaag taagacatgc ccagtttctc
     7141 catattggca aaggcatccc gacgaatatc cctaacaata ctgtaagaca cgcgcgcaaa
     7201 gagaagattg ccgacatact gaactacagt ttgtaggatg tagagaccat agtagaccag
     7261 caaaacggtc acggctagtt ggttaagatt gctgagatac tggtcgataa agtgggaagc
     7321 cacaagggga atgacacttt taatgaccgt cgtcgctagg agaaaactga gtgccaaaaa
     7381 ggtaaggagt ccataaggct tgagatagga catcaagcgc ttcaatacag tccattgttc
     7441 ttgtttattc tgcatcttct tctcccttca tttccagctg ctgagactgg taggtttggg
     7501 cataccagcc atccaaagct agcaagtctt cgtgcctgcc tcgttcgata atttgaccat
     7561 tttgcaggac taaaatcaaa tctgcatgga caactgcact caggcgatgg gcagtgataa
     7621 tggttgtctt gtcctttcgc gtctccttga ggttgtcgat aatcgcatac tctgtcttgg
     7681 catctacggc ggataaggaa tcatccaaaa tcaagatatc agggtctaaa atcatagccc
     7741 gactcatagc caaccgttgc ttttgaccac cagaaagact gactcctttt tcaccaatca
     7801 gcgtatcaaa tccttgaggc atgtctacaa tatcttggta aactcgggct agcttagtag
     7861 cttcctcgac cgctgaaagg ggcaagttag gattgccaaa gcggatattg tctaggattg
     7921 aagtcgcaaa aagaaactgg tcctgaggaa catagcccat gagactgcga aggtctgtca
     7981 gacgatagtc ccgaatatcg tgaccgttta gataaatggc acccttatcc acatcgtatt
     8041 cacgcaagaa gagcttgatt aaggacgttt tcccagagcc tgtctgccca accaagccca
     8101 gtgtttgccc ttttgccaaa ctaaagtgaa tatccgtcag tgtttcctca ttttcaaaag
     8161 caaagctgtc aatggcatac tccaaacgcc cattttcaat accatccaga ggaaactcag
     8221 ggtcttgtac aggagattcc tgagacaaaa gattttcaat ccgctggtaa gaaaccttcc
     8281 ctcgctgagt agtattaaag aggaagccga tggccataag aggccagacc agcatatcca
     8341 aatagctgat aaaggtgact agattaccaa ctgtaatctg cccttcctga accatcaagg
     8401 agccaaccaa aagcgttaaa acataggacg aaccaacaaa caagagaacc atagggtcaa
     8461 agagactatc atatttcatg gtttgcaggt tcttttggaa ggttaattca ttgactgcct
     8521 gaaaagactt caactcgtct gcctgataac cgaaagactt ggtcactttg atacctgata
     8581 cggactcctg taccttgtta ttgagttcag aaaaagcagc ttgggattcg ccaaaggcct
     8641 tatgagtctt tctccctagg cgactagtcg cataggccat gaaaggtagg gggagaatgg
     8701 caacaagagt catctgccat gagatgctaa agagcatggt caacaaagtc accagagccg
     8761 tgatagaggc atccaccgca gacatgacac cgccacctgc taaacgagtc aaggcattga
     8821 tatcattggt tgcgtgtgcc atcagatcac ccgtccgata ggtttgataa aaggctgacg
     8881 acatttttgt gaaatgctta aacaagcgag accgcatgat ctgtcccaag caataagagg
     8941 tcccaaggat atacatacgc cacacatagc gcaaatagta cataccaaag gctgcaagta
     9001 gcaagtaaaa taggctaaga aggaggtcct gctgggttaa ttgccccgat gtgatggcat
     9061 caataacccg ccccataacc ataggaggaa tgagattgag gacggaaacc aagaccaggg
     9121 ccacaattcc gactagataa cggcgttttt ctaacttgaa aaaccaccaa agtttttgaa
     9181 taatggacat aaaatccctt tctgattgca aatggaaacc tgaggccaat actcaatgaa
     9241 aatcaaagag caaactagga aactagccgc aggctgctca aagcactgct ttgaggttgt
     9301 agatagaact gacgaagtca gtaacctaca tacggcaagg cgacgttgac gcggtttgaa
     9361 gagattttcg aagagtacaa gaccccaggt ttttcttatt cataagttac gactgtaaca
     9421 gcacccttgt catattcagc aataaagata ttggctacat tgtcatgccc ttgtttactg
     9481 aggttatcaa gcaaccactc ttcgctacga ccaatcgatt ccaagacatc tacttgaatc
     9541 acaccgtcag tcacaactgg atacttagga ttttcatctc ccatttgcac aacgatgagt
     9601 tgcccatttt gctcttgcac agctcgtttg acttgcttca tctggaaaat cccttggcta
     9661 cgaagtttga gggctacatc cgatgcagac aaaccaactg aacgacaggt ttatggggca
     9721 atattcccat ttttgataag gagagttggc ttaccatcaa tcaaacgttt cacaaagtga
     9781 acattgttgt tgagccattt gagagtcaag accagtttga ttaaaatttc gatataatta
     9841 agtgtcattt attcacatcc accagttcaa ttgcgtctgt cttatacaat tcgactttct
     9901 ctaacaggta cttgtctggc tcacttccgt ttagggcacg ataatagcga tctcccacct
     9961 tgataagtgc gccatctgtg tttgtggaag tattaacata gacttctgac ttgtctactc
    10021 ccaaatcttt ggaaacaacc tcgatgaaat gaagtgaagt ttgaaattta ttgttagaaa
    10081 cttgattgtt ttgataagtc gtgatgctga ccaaaagcag agctaaataa ggccagagct
    10141 gaaatcatga ccaactcacg aaattcggtt ccctttttat catggtatgc cttaaaagca
    10201 aaaaaactgt cacagctaat agaacaatcc caaagccaac catgatacca ttttgctgac
    10261 cgatttggct gagtacatag tcataagagt agaatttcat gtattttcac tccctttcat
    10321 aaaatcattc ttaattataa acgaaagaga gtaatttttc aaactatacg ttggggaaat
    10381 agatcttttt ttggtataat aaaatctata atctgaatga aaaaggtaac tttatgaaac
    10441 ttatctcatg gaatattgat tccctaaacg ctgccctaac tagtgactca gctcgtgcca
    10501 aattgtccca agaagtccta caaaccttgg tcgctgaaaa tgctgatatc attgctatcc
    10561 aagaaaccaa gctttctgcc aaaggaccta caaagaaaca cgtggaaatt ttagaagaac
    10621 tcttcccagg ctacgaaaac acgtggcgtt cttcccaaga gcctgcccgt aaaggctatg
    10681 ctggaaccat gttcctttat aagaaagaac ttacacctac tatcagcttc ccagaaatcg
    10741 gtgccccttc taccatggac ttggaaggtc gtatcatcac tctagaattt gatgcatttt
    10801 tcgtaaccca agtttacact ccaaacgctg gtgacggtct caaacgcttg gaagaacgcc
    10861 aagtctggga tgccaaatat gctgagtatt tggctaaact agacaaagaa aaaccagtcc
    10921 ttgcgaccgg tgactacaac gtagcccaca atgaaatcga ccttgcaaat cctgctagca
    10981 accgccgttc acctggattt actgacgagg aacgtgctgg atttaccaac cttttggcaa
    11041 ctggatttac agacaccttc cgccatgttc atggcgatgt tcctgaacgc tacacttggt
    11101 gggcacaacg cagcaaaact tctaaaatca acaatacagg ctggagaatc gactactggc
    11161 tcacaagtaa ccgtatcgct gacaaggtca ctaaatctga tatgattgac tcaggtgctc
    11221 gccaagacca tacaccgatt gtcttggaaa ttgacttgta aggattttct atatggacta
    11281 caatgcggtc attcccgagt tgcttgtatc gaatatcgaa cagtcccggt ccttctactg
    11341 tggtttactg ggttttagga ttgaatacca acgtccagaa gaaaactttc tctttctctt
    11401 gaagagtgtc aactaatgtt agaggaggga acaaaggatc aactagctga actgacctat
    11461 ccctttggtc gtggagtcaa tctctccttt ggcataaagg atgtttcaaa actctattaa
    11521 agagtgatga aggcaaacta tcctatttat cgtcccttga ccaagagaaa gtttcgtgtc
    11581 agtgatccct atatctatcc tcatgaattt gcagttttgg atccaaatgg ctatttttta
    11641 agatttagcg agtagaataa taaaaattgg gaaaagtctt taaagttaga aaaaggcata
    11701 ttgtcagatg tctaaaaact tgatagtatg ccttttatga tggaaaaatc ttctaatact
    11761 attcgaaaat ctcttcaagc cacatcaacg tcgccttacc gtaggtatat gatactgact
    11821 ctgtcaattc tatccacaac ctcaaaacag tgatttgagg ttgtggatag cttcctagtt
    11881 tgctctttga ttttcattta gtataaatgt tagcttacaa cggagttttt gttcaccccc
    11941 tcttctgttt gttcgttttt taaaccaaaa cactaacaaa atagttgatt tataaagtta
    12001 tttagtgtaa aataaaaaca ttggctcaag cctatttaaa attgaatatc gttttacttg
    12061 tttatgtcgt gaattggcac gacgtttcta caaggtgccg gaacacctaa caataagtaa
    12121 gtcagcagtg agatatggcc gtttttgcca tgtctattta ggggacttac ttagagatta
    12181 agtaggtctt ttttgaatat ttttaatatt tcccttaatt agtgcggacg ggaggtgaaa
    12241 ttatcctgtg aataatttca ggaatccagg gaatttcatc cctaattttt gagcccctag
    12301 ctctttcatt tctaggctta ggctaaaata gttccccgaa ctattttact ctcaaaaatc
    12361 ccgtcataga caataacaag attattgtct atgataccac tacaacggga aatatttgat
    12421 aagactcgct tcgctcgtaa tagttttatc aaatatatag tattagcaaa agggatcact
    12481 atagaaacat ttaaacaaca agtaaattag cttttagact ttaggaggtc ttatgaaatt
    12541 attagaagag cgcatcctca aggatgggca tatcttgggt gataacatcc tcaaggtaga
    12601 ttccttttta acccaccaag ttgactttag cttgatgcga gagattggta aggtttttgc
    12661 ggaaaaattt gctgctgccg gcattaccaa ggtcgtaacc attgaagcgt cgggtattgc
    12721 cccagccgtt tttacagctg aagccttaaa cgttcccatg attttcgcca aaaaagctaa
    12781 gaacatcacc atgaacgaag gcatcttaac tgctcaagtc tactccttta ccaagcaggt
    12841 gaccagcacc gtttctatcg ctggaaaatt cctctcacca gaggacaagg ttttgattat
    12901 cgacgatttc cttgctaatg gccaagctgc taaaggcttg attcaaatca tcgaacaggc
    12961 cggtgccaca gtccaagcta tcggtatcgt gattgagaaa tccttccaag atggccgtga
    13021 tttgcttgaa aaagcaggct accctgtcct atcacttgct cgtttggatc gttttgaaaa
    13081 tggtcaggtc gtatttaagg aggcagatct ctaatgcaaa ctcaagaaaa acactcgcaa
    13141 gcagccgttc ttggcttgca gcacttacta gccatgtact caggatctat cctggttccc
    13201 atcatgattg cgacagccct tggctattca gctgagcagt tgacctacct gatttctaca
    13261 gatatcttca tgtgtggggt ggcaaccttc ctccaactcc aactcaacaa atactttggg
    13321 attggactcc cagtcgttct tggagttgca ttccagtcgg tcgctccctt gattatgatt
    13381 gggcaaagcc atggtagtgg cgctatgttt ggtgccctta tcgcatctgg gatttacgtg
    13441 gttcttgttt caggcatctt ctcaaaagtg gccaatctct tcccctctat cgtaacagga
    13501 tctgttatta ccacgattgg tttaaccttg atccctgtcg ctattggaaa tatgggaaat
    13561 aacgttccag agccaactgg tcaaagtctc ttgctttcag ctattactgt tctgattatc
    13621 ctcttgatca acatctttac caaaggattt atcaagtcta tctctatttt gattggtctg
    13681 gttgttggaa ctgccattgc tgctactatg ggcttggtgg acttctctcc tgttgcggta
    13741 gctccacttg tccatgtccc aactccactc tactttggga tgccaacctt tgaaatctca
    13801 tctattgtca tgatgtgtat catcgcaacg gtgtctatgg ttgagtcaac tggtgtttat
    13861 ctagccttgt ctgatatcac aaaagatcca atcgacagca cgcgccttcg caacggttac
    13921 cgcgcagaag gtttggcggt acttctcgga ggaatcttta acaccttccc ttacaccgga
    13981 ttttcacaaa acgttggttt ggttaaattg tcaggcatca aaaaacgcct gccaatctac
    14041 tacgcagctg gtttcctggt tctccttgga ctgcttccta agtttggtgc ccttgcccaa
    14101 atcattccaa gctccgtcct cggcggtgcc atgctgatga tgtttggttt tgtatctatt
    14161 caagggatgc aaatcctcgc ccgagttgac tttgctaaca atgaacacaa cttccttatc
    14221 gcagctgttt caatcgctgc aggtgtcggt ctcaacaaca gtaatctctt tgtcagcatg
    14281 ccgacagcct tccaaatgtt cttctcaaac ggaatcgtcg tagccagcct actcgctatt
    14341 gtcctcaatg ccgtattaaa tcataaaaag aaataagaaa aagaggtgcg agcctctttt
    14401 ttgtgtgaca aaataaaaac atctacctat tcatatatgc tagtgtcata gtcctgaaaa
    14461 tcatctgcat caagaacaat ttcacaactc ttatactttt ctcttacaag tcgttcggct
    14521 tcatctggat tttcagcctc tatacttact aaacgtgata aagtttctgt aatttctact
    14581 gtatactttt tcagttttag attgctttcc aataattcac ctattaacaa taatctatga
    14641 taggagctat gtagccactc tggcaattta tctcctactt cccacccata tttttccttc
    14701 atcaaagcta gttgtttttc gtcaccaaat ttcatatttt cagataacca tctcacacaa
    14761 tcgggatctg ataaggtaca gacgattaaa cttaggttat cgtaacggct ttcagtttca
    14821 taatcaggcc agatgacttt taagaaatca tacacctctt ctgatgcaac aagttgtttc
    14881 gttttcataa tttccgatac tttcctctac ctttaaattc tattatttct ttgtctctta
    14941 atatttgaag ctgttgccta atcttttctt tgatatgatt gttcttaaca aagatatttt
    15001 ttaggtcact ttcaaaacga tacatatctt caagggtaaa ttctgaaccc tctatcttat
    15061 ctatacaatt tagaatttct attgtccaac ctcttgatga cagagagctc ttccttaaaa
    15121 ataaaccttg cttaaattct tttgtaactt tttctggatc tctaacttgt ccatcttgca
    15181 caagaaatat ccttccttta gaaggtactt gtgataaatc aatgttacaa ccaatccaac
    15241 ctgctcgtct agcagttggt gcaagtggtt ttctttgaat aatcgatttc ggtgtaacaa
    15301 attgcttcgg aaggacaaga aagttattta cctcaaaatt ttttgtgtaa gttaaaaaaa
    15361 agaaattagg attattatct gcctgcacac gcttcatcat cgttgcataa gcaccatcat
    15421 tgattgttga tgaaaaattt ccttttttgc tctttagttc aaactcctca ctacaatgat
    15481 tacagtaaaa atctgctaca ggccgattat tttcaaaatg atttaaggga ttgttcccac
    15541 aattagggca ataagactga cgataaaccc aatcctccgt taagatacgt gccttttggc
    15601 tattactttt ataggtttct actaattcta aattaaagtg taattccatt taaaaattcc
    15661 tcactaatat gagaactcac tcgatataag caattaaaat ctactataac tagtatacca
    15721 catatatgta cctattacat ttgtatttca tcactctctt ttatatttcc ttctaacata
    15781 tctcataaat taaaaatgag tgagataaat ttatcccact cacctttctt tatatactta
    15841 cccgtctttc ctcagacctt tggcctgtga caaacatggt aaaggttgcc ttacagacat
    15901 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    15961 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    16021 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    16081 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gatgagttca
    16141 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    16201 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    16261 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    16321 cgacctgttc cacaaagcgc ataaaggctg tctgcccttg ttctgtctgc ttgtagactc
    16381 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    16441 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    16501 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tctacttctt
    16561 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    16621 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    16681 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    16741 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    16801 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    16861 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    16921 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    16981 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    17041 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    17101 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    17161 catagggcga atactggaaa ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    17221 ggttggtgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    17281 gacactgagg ataattacta gcttgcacca acttggctgc cgcaatctct ttcggatcct
    17341 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    17401 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttctga ctgagttgat
    17461 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    17521 cctgactcgg acaaggagtc accaagtcca tcaattcagt accaaggatt tcacgcgcag
    17581 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    17641 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    17701 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    17761 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    17821 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    17881 gtttgcctac agcttcctta aaggcctcaa cagtatcttt ttgaaccaag gcaatggcac
    17941 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    18001 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    18061 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    18121 ctttaagggt acgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    18181 ctttaatcaa atagctatat tggtcaacgg cccactcgtc caattcaccc agggtctgaa
    18241 tatccaaggc aacttgcaat tcttccactg ctttttcaca ctcagcacga cgttcattgt
    18301 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    18361 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    18421 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    18481 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    18541 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    18601 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    18661 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    18721 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    18781 gtaaaacttg gtcttcacgc ttgcgagctg caccataagt tcccaaggaa atagcagctg
    18841 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    18901 aaaagaaggt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    18961 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    19021 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    19081 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    19141 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    19201 cccgtgttct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    19261 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    19321 ccaagcaaaa gattgccatt attcaatggg tcagcgaaca aggggagcta gacgacctct
    19381 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tacgatatct
    19441 tgcgctattt taatgaccac ccttttaccc taagcgagga agtgattggg attctctgca
    19501 tcggaaagtt tagtcgagct cagatttctg cctttgaaga ataccaaaag cctcttgtat
    19561 ttctagacag cgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    19621 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    19681 caggccttga agaaacaact gaccaagaag aaatcattga ggataagcgg ctggaaaatt
    19741 tcagaaacta cagtcaagca aaaggaatct atcatgatga actgatcttt caaggaaact
    19801 ttactgccca gtctggctat gacttgatga aggaagccat tcagaacttg ggagaccaac
    19861 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    19921 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    19981 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    20041 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcggaaaatc cctagcctga
    20101 ccatgctggg aaccaaactg acgttaagag aaagtactct aaatcaagaa taggataaca
    20161 taaaaaacga ataggagttt tagaactcct attcgttttt tattcgatta caatcataga
    20221 cttaatggtc ttacgttcat ccatatcttt gtaggcttgg tcgatatctt ccagtttata
    20281 acttgaagta aagacgcgac ctggattgat atcaccatca aggacggctt ttagtaaaaa
    20341 ttgcttatcg tatgttgtag cagaagctgc cccacctgct acagagatat tttgcataaa
    20401 tgtcgaacca agagcacgat tattatagtg tgggactcct acaaagccca tacgccctcc
    20461 attatgaaga acacctagcg cctgttctat agcagcctcc gtaccaacac attcaagtgc
    20521 tgcatctgct cctccaccga ggatttcacg cacctttgta attccttctt gaccacgttc
    20581 tgcaacaaca gctgtcgcac ctgactccat agccatcttt tgacggtctt catgacggct
    20641 cataaggata atttgtgatg ctccacgcat cttagccgcg atgacagcac attgaccaac
    20701 agccccatca ccaataacaa caaccttgtc ccctttttga acatttgcaa cacgcgccgc
    20761 atgatagcct gtcggcatga catctgcaag agtcaaaagg gacttgagca tcccttctgt
    20821 atagtcagaa ggttgaccag ggattttaac cagcgcccag tttgcatagt ggaagcgaat
    20881 atattctgcc tgaaaatcac cccccaaatt attgccaata tgattgtcgc aagaaccgtc
    20941 aaatccagca agacaggcat cacactcacc acatccatgt gtaaaaggga caatcacaaa
    21001 atcacctggt ttcaccgtcg taatggcttc cccagcttct tcaacaatcc caatcgcttc
    21061 gtgtccacta tttttgtgtc cagctttcgt ttctggatta cggtacctcc ataaatctga
    21121 accacaaacg cacgaacgaa ccacacgaat aatcacatca tccgcttcta ttatttgcgg
    21181 acgttcaatg ctagcaagtc caacctgacc tgcctttgta tatactgctg atttcattta
    21241 aaattttcct tccttataaa gtttaatttt gagatttaaa cgatttaaag ctgtctgtag
    21301 ctgagacaag cgctcctcta atttttgctt ttcctcttct aaaataccaa gcctctcctc
    21361 tctcgtttca tctccctttt ggtagagcga catatagtca actaaactat ctacagagac
    21421 acccgccgaa cgaaaacact taataaattc cagcgcttcg atatcctgaa cttgaaaatc
    21481 acgaatccca gtagcagtac gagtaatcgg tggcacaaga ccaatccgtt cataataccg
    21541 aatcgtatcc gctgaaattc ccaacaaatc actggcggat ttaatattca cacgctaacc
    21601 tcctctcatt tcattcactg aattcacgct attctaactc acttatctta ttatataact
    21661 ttgagttgac tccaagtcaa gcattttgta tctaatcgaa aaatttttat cattaacaat
    21721 catatatctg gagtttatac aatgctcttc tcttaccaat ttttgaaata tttaaataat
    21781 aaagaaatta ctctattcca aataagatag tacccaagta tttttcactt ttttctaatg
    21841 ttgatgctca taactccgtt ccaagtcaca cacctttcgc ttatgggttt ggtgagtttc
    21901 taggtcagca tcaatttcaa tggtaatatt ttgaaaacca caatctttta ggaaaattcg
    21961 aatagactct ttacaagttt ccatatgttc catttctttt agacaaacat ggacaatggc
    22021 atttttttcc aaagcatcca tagtccagag attaagctga ttaaggctgg ccacattgtc
    22081 caatcgctcc aggccactct ttacttgctt gatatcaaga ccttctggca cagcatccaa
    22141 gaaaatcttg agtgtagacc aaaaacgtga aagggctttt gaaagaataa agaaagaaat
    22201 gacaagggac aaaagaggat ctaggatata ccagtccgta aatcgaagaa caatcgccat
    22261 caggataaca gctacccacc ctagcgtatc ttccagaaaa tgcagactca gaatagactc
    22321 attctttgtc tttcccttac caaccaccag actcgctaac agattgatag taatcgcaat
    22381 aattcctaac cagagaatcc cctcatcatt gactggttgc ggatgcaaaa tcttcgtgac
    22441 attttccaaa atgactagaa cagagcccgt tacgagaatc acagctatta ccaaggctcc
    22501 tagcaggcta aaccgcttat agcccaaggt gtactgattg tcttcttcac gattggagat
    22561 tgtttctaga aaagctgata ttccaattgc aatcgcatct cccaagtcat gcacagagtc
    22621 agcaagaaca gcgctagaac caaatactcc acctgcaata aactcaacaa tggcataagt
    22681 caaatttaag aaaaaagcca cccaaacagc atattttgcc ttcatatttc tcattccttt
    22741 gttataatag atttatgaac accttgttca ttatcattat ccactaaaac tcaaagaaag
    22801 gatagaagca aaacgtcagc tttattcagt tctgaacaat ttgccttaag tgtccatatg
    22861 actaacattg accgccgtat cagcaaaacc aaaaaagcca tctatcaagc ttttatacaa
    22921 cttttgaatg ctaagggcta cgaggccact actgttcagg atatcattga tctcgcagat
    22981 gtgggacgat ccacctttta ctgtcactat gagagtaagg agcttcttct ggaccagctc
    23041 tgccgctacc tcttccatca tctttttgaa agagagcaag ccatttcaac cgagaattac
    23101 ctcgcccacc tctttctcca ttttcataaa aaccaagacc atatcaccag tctgctattt
    23161 tccaaaaatg actacttcct ccgtcaactc cataaagagc tagaacacca tgtctattcc
    23221 gtgctagctg ataatttaaa agaagcccac cctaatctgc ctacttctta cctccaacac
    23281 ttggtcatgt ccaactttat cgagacattg acctggtggc tcaaaaaagg tcaagatttc
    23341 acagaccagg aagttgtcca attttatcta gaccttctca ttcctaaaaa ttgaatatag
    23401 agtaaagctt cagttgtctt atttctaggt tactgagttt tttatctttt caacaacaaa
    23461 agaggacccg ccgatcctct ttttcatact ataaatcctt gattatcaac tatatctgtt
    23521 ttaatcgaaa tctcaaaaca gcactttcaa acatcttttc ctagttaagt aaatcagtat
    23581 tctgcttagc tgccttgctc cattgatacc aaccaactag actgttaatg agataaatta
    23641 gatatttccc ttgaatttgc aggctttctc cccaccagag atagattgaa aaaacattgg
    23701 tagccgccca gaatatccac tgttcacggt aaacagctgt catgaggatt tgccctaccc
    23761 cattggttgc atctgtgatt gaatcacgat agggacgatt ggcaccaata gactgataaa
    23821 tgaagccaaa ggccaaccac caaagcacac taatggaaag atactttgtc cagcccttgc
    23881 cgtccagttt acgcgcgaca aactcctgct tttccttctt aaactgtgcc tgataaatcc
    23941 aaactagaag tccaattggc tgcatgactg tgaagtaaag tgtcgtcagc acctcaccat
    24001 aaaagccttt ctgtagggcc aaaataaggt aaataacaga gttaatcaag ccaaaaagat
    24061 aattacttgc tcgaccttcc gatacaaaga ttacacagat aatccctgtc aagctacaaa
    24121 tcatcccaat ccagtcaaca atacgatgtt cgtaaaccaa ctccagccag agaggaaaac
    24181 ttcctaaaac cagcaaataa atccactggg caaaactacg atgggcaaag aggtcatccc
    24241 agatagcctt catagttcct gaaaatccta aatcagccat agccgcaacc atacgacggt
    24301 aaccacctga catttcacct agggttgttt tgatattttc aattttcttt tgcaaataag
    24361 tatgcatcat ttctcctttt gtttttaaag agccgtgtct ggatagactt tcggacgcaa
    24421 cgctctatta gataatgaac tgcctataca caagatttct aaccttagtc gacatgagct
    24481 gaaacctctt atttgttaag tagttcacaa aatattatac acctatttta tgaatagtca
    24541 actgtcttta cagtaaaatt ttagaaaatc atgaaaattt tctctttctt tccattttaa
    24601 gtgacattca gtcattctca catcaaaaaa gcccagacga aattgtctga gcattctttt
    24661 atctagtcgt ttaaggaagt tgagttcagt atgtttaaag tctctgtccc atcatttctt
    24721 caacaaacct tgttcttgga gaaactcctt ggctacttgc tttgctgact tgccttcaac
    24781 accgacttgg tagttgagct ggctcatctg gctttctgta atcttaccag ccaatgtatt
    24841 aagaactctt tccaactctg ggtgtttctt gagaagagct tctttcatga gtggagcccc
    24901 ttgataaggt gggaagagtt gcttgtcatc ttccaagacc tgtaaatcat aacgctccaa
    24961 ttccgcatca gtcgaatagg catccgtgat ttgaatatcc cctgactgaa ttgcctgata
    25021 acgaagagct ggctgcatag tcgccacatt gagattgaga ccatacattg attgcaagcc
    25081 cttatttcca tcttcacggt cgttaaactc aagcgtaaag cctgccttca gctgcccttc
    25141 cacttttttc aaatccgaaa tggtcttcaa gccatattct tgagcaatct ttttcggaac
    25201 agctacagca taggtatttt gataagacat aggtttgaga taggctagat gatcctgctt
    25261 ggcaatacca tcacgcgcca cttgataaac ctgctctggc tcatgactca ccttgggtga
    25321 tggttgaagc aaactttcag tcaccgtacc ggtaaattca ggataaatgt caatatcacc
    25381 ttttttcaga gcttcataaa ggaaacttgt cgtcccaaaa ttcggtttaa cagtcgcagt
    25441 catgctggta ttttcttcaa tcagcaattt atacatatta gccaaaattt ctggttctgg
    25501 gcctattttc ccagcaataa tcaagttttc cttctctttt tgagccaaaa gggctggact
    25561 ataagacaga cccagtaata aagccatcaa ggcaaaacca gagaaaatcg tccgcaattt
    25621 cgctttttcc attactttta gtaggaagtt aaaggcaata gctagcactg cagaagaaag
    25681 ggccccaatc aaaatcaaac tggcattatt acggtcaatt cccaacagga taaaggaacc
    25741 cagtccccct gccccaatca aggtcgccaa ggtagccgta ccgataatca agaccgctgc
    25801 cgtccgaatt ccagacatga taacaggcat ggcaagtgga atttcaaact tcttgagacg
    25861 ctcccatctg gtcatcccaa aggcaatccc agcctcttga agactcggat caattccctt
    25921 cagcccagta atagtatttt gtaaaatcgg aaaaatcgca taaatcacta gagctgtcaa
    25981 tgccggtaaa gtcccaattc ccatcaaggg aataaagagt cccaacaagg ccagagacgg
    26041 gatggtctgg aaaatccctg caatctgtaa gacccaatcc gccaacttct catgatagcg
    26101 aagataaaca gccaagggaa tcgcaagcaa aatagctagt aacaaggtca aaagtgacaa
    26161 ctgcaaatgt tgagataggg ctgtcaacca atcaccaaaa cgatcctgaa aagttgcaat
    26221 taaattagtc atgaatacta cctccaaaca agtctgcaac aaagtctgtt gcaggagctt
    26281 ttaaaatagt ctcaggattc gacacctgac gaatctctcc atcctgcaag acagcaatac
    26341 gatctgccaa ctttaaggct tcatccgtat catgagtcac aaaaatcgtt gtcatcccaa
    26401 actctttatg taattctttt gtcagaacct gcaactgctt gcgagaaata gcatccaagg
    26461 ctgaaaaggg ttcatccatg aggagaatct tgggctgacc aatcatagct cggacaatac
    26521 cgacccgttg ctgttctcca ccagatagct cacttggaag tcgatgccca tactcagcta
    26581 ctggtaaacc aaccttagcc aaaagctctt ctgttttttg agcaatttct tccttagtcc
    26641 aacccttcat ttcaggaatg agagcaatat tttcctcaac tgttagattg ggaaagagag
    26701 caatagcctg taaaacataa ccagtagaaa gacgaagttc acgctcatca tagtctttga
    26761 tgcgcttccc atccatataa atatttccat cagttggttc caaaagacgg ttaatcatct
    26821 tgagcatggt cgtcttacct gacccagaag gccctactaa aaccataaat tccccatcct
    26881 caatctgtaa gttgacatct ctcaagacat ccttttctgt gtagcgcagt gctacatttt
    26941 tgtattcaat cattctttgt cctcaattta aaacttccct cgattagtca agtcttctac
    27001 cttaggcatg acttccttat tatcccaatg ctccacaatt ttcccgttct ctaaacggaa
    27061 gatatcgtac tgggcataag caacgccatc aatctgagtc tgaccatagc taaccacata
    27121 gtttccttgt cctaagagtt ggaaaacaaa gtcaaaagtg acactatatt cagccacata
    27181 atttttataa gcagcacttc cttgtccaat atcatgatta tgctgaatca aatcgtctgc
    27241 cacataatca ctccactgct ctagctcccc attttggaaa atttctgtca agaaacggcg
    27301 aaccagcttt ttattttctg ctttcttgtc caaatccttg atttcaaaat ctccaaaaat
    27361 ttgatctagt tggtcatttt caggtgttcg atagtagtca atgacatccc aatgctcaac
    27421 aatacgacca ttctcatccg cacggaaagt atccgtcgtc acccattgag cttctccacc
    27481 attcagatat tgatgaacat gaacaaagac cagattgcca tcctcaatgg tgcggacaat
    27541 cttaatctga cgctctggat gacgctcaaa gaaatctgca aagaaggctg caaatccttc
    27601 tttcccgtca ggaacacctg tcgaatgttg gatataggta tcccctacag actgggcttg
    27661 agcctcagca actcgtccgt cttgaatggc atggatgtat aggttgtgag catttttcac
    27721 ttgttgtgac atattctaaa cctcatttcc cttctctttc agattcgcca aaattctttc
    27781 ttgaaaacct tcaaattggt gaatttcttc ctctgaaaat cctttgtaaa agatagtatc
    27841 caatttctga ctgacacgat gccccacttc tttctgggac ttgcctaact ccgttaaaac
    27901 taaatacttc ttacgcttgt cttttccaca cggactaaca attacaagct tttgttcctc
    27961 tagctttttt atcatagtcg tcagcgtatt attcgcaagc ccagtcgcaa gcgcgatatc
    28021 tgtcgcagtt gcgcagccag tttcactatt ccataaaacc gctaaaatct tgccctgttc
    28081 acccctataa agagcctcag gatcttgact cagtaacttt tgaaaaatcc gcccattcaa
    28141 caaacgaata tgatgggcta gcaaatgact atctttcata acacctccaa tttatgtcga
    28201 tatcgaaatg aataaaataa ttgtaacact catcgttcta actgtcaact atttcgattt
    28261 ggaaataatt tttgataatt atccacacca ccatactccg aatcaactaa cttttaacga
    28321 gagtttctaa attccttcgt cctccagtct acaaaagcct tccatccgta ctatcctata
    28381 ttttatgagg ggacacattt ttcctatcag accatttatt ttaaagatag aagtaaatca
    28441 taattgcttc catctgttct tttatagtat attgaagttg aactagggca ctgtatcttc
    28501 taaaacattg ataaaaagcg atttgaattt cccaatcaat ttgttcgtat ttatagcatt
    28561 ttgaaattgg aataggacac catgactgct aaaagatttc tataaattca tttgattttc
    28621 ctaatcaatt tgttcatatc ttatttcatc ccgctataat ttcaccttgc cctatctttt
    28681 tcgtagcacc cttcaaacag cctatcccct accgtttgac gattcctcac ttcgctccac
    28741 ttccattaca gaagtttctt cactactatg gtctcggctg acttctcatg attccttgtt
    28801 actactattt gaacgctcac gagataggtc ttacaaaaaa tgctttgatc cacaatggaa
    28861 tcaaagcatt ttaaagagtt cctcatacat aagcgcagaa gtcgcagttc ctctgtactt
    28921 ggcttcttct cttttgataa agcgagccaa gttgagcaac tcaggtgctg gatgtttggg
    28981 atttaggagc aattcacgat tgaccaggcc tgagagacga actgcctgca attgctcatt
    29041 tgtagtaggc agttttttag cagtctctag gagagcagca actaaatctt cactcaaatc
    29101 atgtcgagca tgattgtaaa gatcttttat aaggctttct aggtttggtt ctaccatccc
    29161 taccacctcc cttatggttt aataatgttt aatcaaatca accgttgaac gatccaattt
    29221 cttcaccaag gcttgtaaga aagcttgcgc ttctaggaag tcatccattg catagagggt
    29281 ttggtgagaa tggatataac gagcgcagac accgatagtt gttgatggga caccaccatt
    29341 tttcagatga gctgcacctg catctgttcc gcctttacca cagtagtatt ggtacttgat
    29401 gccagcttct tcagccgttg tcaaaaggaa atccttcatc tctgggagaa gcaagtgacc
    29461 tggatcatag aaacgaatca aggttccatc tccaatcttg ccttgaccac cgtagacatc
    29521 acctgctggt gagcaatcaa ctgcgaggaa gacttctggg tcaaacttgg ttgtagaggt
    29581 atgagcgcca cgcagaccaa cttcttcttg gacgttagaa cccagataga gttcattgcc
    29641 gagtttttga cctgataaag cttcagctag ctcgcttacc atgaggacac cgtagcggtt
    29701 atcccaagct tttgagatga tatttttttc attggctgtc aaaattgcag aactatctgg
    29761 tacgatggta tcaccaggac ggatgccaaa actttctgcc tcatccttgt ccgcaaaacc
    29821 accatcaaaa acgatatcgg caatggctgg catggttggt cccccctttc cacgagtcaa
    29881 atgcggagga acagaacctg aaatcacagg aatttcatga ccatcacgag tcaagagttt
    29941 gaaacgttgg ctgctaacca ccatggggtt ccagccaccg atttctacga cacggaaggt
    30001 accatctggc ttgatttcgc tgaccataaa accaacttcg tccatatgag aagcgaccaa
    30061 gacgcgcggt gcatccacag cttctgaatg tttgatacca aaaataccac ccaagccatc
    30121 tgtcaccact tcatccacat gcggtgtcaa cttttcacga agataagcac ggacaggcgc
    30181 ttcatgacct gagactgcag caagttctgt tacttcttta atttttgaaa ataatgttgt
    30241 catttcagtt ccttctttct ttcatccatt ttaccacttt ttataggaga aggatagtgg
    30301 gaaggtggat ttctaagtta gtatcttagt cctgctctat cttagaaaag gatagtattc
    30361 tcttgcatgt agtgcaaaat ctagtaaaca ttccaaaatt aactcgaata tttatttcca
    30421 aacaaaaaaa caatacacca tcaaagttgt ttaggttttt catgaaattt acagaaaata
    30481 gttgacttcc ctttcttctt tctttaaata tatagttggt tgagtttgga atagtacgct
    30541 gtagctgcta aaacatttct agaaattaat ttgactttcc taatagagtt gttcatatct
    30601 tatttcaatt tactatagta caaaactaga aaaggaaaaa atcatgacca aaacaattct
    30661 tgttacaggt gggactagct acattggctc ccataccgtt aaagctcttt taaatgctgg
    30721 ttataaggtg catgtcctcg ataatctctc cacaggaaat cgagcggctg tgggtagtcg
    30781 tgctagcttt aaagaactgg atgtttatga tgctagcgcc ttaaaggctt acttagaaga
    30841 aaatcagatt gatgctgtcc tccattatgc aggtgaaatt gttgtgagcg aaagtattga
    30901 aaatccaagt aaatacttca ctgccaacgt tgctggtatg gaccaagttc tcaaagtctt
    30961 atctgaagtt ggcattcaaa aaatcatgtt ctcttcgact gtttctctct atggaaataa
    31021 ctgtattgac aagccggtga ctgaagatac cctgctcgac cctgtcaacc cttatgcaga
    31081 gacaaaactg atgggcgaac gaatgattta ctggatggcc aatcgctacg actggaaata
    31141 tgttattttc cgttacttta atgttgctgg ggctgaaatg gatgcttcaa acggtctgcg
    31201 tgtgaaaaat ccaactcaca tcattccaaa tatcaacaag accgcattgg gacaaaatga
    31261 tagcttaaaa atatttggag atgactacga tacacgtgac ggttcatgta ttcgagatta
    31321 catttatgtc ttggaccttg cataggctca tgttaaagga atgaactacc tatttcaaga
    31381 agacagttct tctcaaatct ttaacttagg aactaaaaaa ggctatacta tcaaagaaat
    31441 ctttaaaact gctgaagaat tactaaatta aaaaatccca cacgagattg ttgctcgacg
    31501 tgctagtgac ccagccagtg tcctagcaga tgcttcaaaa gctaaacaat atcttgattg
    31561 gacggctagc tactccctcg aagatattat tttatcagat taaggtaaaa acattttaga
    31621 ataggataac aaaggagaaa gtcttgttgc tctctccttg ttgtatttat taaattgtca
    31681 gaaattttat tgacagatta gaaaaataat gttacattta tatccgcagg tatctttcga
    31741 taccaaatct acatgaaagg acggggtatg aaactttctc attatttaat tggcttactt
    31801 ctactcctag tctttctctc tattagcatt gggaccagtg atttttcatg gggaaagcta
    31861 tttgatttcg accagcagac ctggctcctc tttcaagagt cccgtctccc aagaactatc
    31921 agtattctcc tgactgcctc tagtatgagt atggcaggcc ttctcatgca gactattacc
    31981 caaaatcagt ttgctgcacc gagtacagtt ggaacgactg aagccgccaa actgggaatg
    32041 gtgctgagcc tttttgtctt tccatcggct agtctgaccc aaaagatgct cttcgctttt
    32101 gtttcatcca tcgtattcac cctcttcttc ctagccttta tgaccatttt tactgtaaag
    32161 gaaaggtgga tgttgcctct gattgggatc atctatagcg ggattatcgg ctcagtcaca
    32221 gaagttatcg cctatcgttt caatctggtt cagagtatga ctgcctggac ccagggctcc
    32281 ttctccatga ttcagaccca tcagtatgag tggctcttct taggcctcat catcctgata
    32341 accgtttgga aattatccca aaccttcacc atcatgaatc tagggaaaga aaccagcgag
    32401 agtttgggga tttcctactc cctacttgaa aaactggccc tctttctggt ggcgctaacg
    32461 acaagcgtca ccatgattac cgtgggtggc ttaccatttc tcggagttat cgttcccaat
    32521 cttgttcgca agcgctatgg agataatcta agtcaaacca aactcatggt cgcactggtt
    32581 ggtgccaatc tagttctggc ttgcgatatc ctatcccgag ttctgattag accctatgag
    32641 ttgtctgtca gtctcttgct aggaatcatc ggtagtctcg tctttatcct acttctctgg
    32701 agagggggac gaaaagatgc agactaaaag caaacatacc aagctcttct ggattctcat
    32761 tattcttgcc atcggagctt gtcttctcta cttttggccc atcactcact tgtcagcctt
    32821 tgcttggaag ttgcgttccc aaaagatcat cgtttatctc ttggtagcca tcgcgactgg
    32881 gatttcgacc attagttttc aaaccctgac ggaaaatcgc ttcctgacgc ctagtatttt
    32941 gggaattgaa tccttctacg tcctactaca aaccctacta ctggtttttg aaagcaagtt
    33001 tcttcaactt ggcaaatccc ctatcttaga attcctagtc ttacttcttg tccagtccct
    33061 cttctttctc gccttacaag gttacttgaa gacactgatg aagcaagacc tggtcttcat
    33121 cctgctgatc tgtctagcgc tcagaagtct ctttcgaaat atcagcacct tccttcaagt
    33181 cctaatggat ccaaacgaat acgataaact gcaaaatagt ctttttgcct cctttcaaca
    33241 tctcaacact tccatcctag ccatcggttc tctgatcatc ctcgctttga caatcttttt
    33301 ctttcgaaaa gcagtcgttc tagatgtctt gcacctgcaa agagaaacgg ctcagatatt
    33361 gggactcgat gttgaaaaag aacagaaaga gctcctctgg ggaatcgtgc ttttgacctc
    33421 aacggccact gccttggtag gacctatggc cttcttcggc tttatgctgg ccaacctcac
    33481 ctacctgatt gtcaaagact atcagcacaa gttactcttt atagtggcca ttctggttgg
    33541 atttattagc ttaaccttgg ggcaagcctt gattgaacga gtctttgcac tggaaattcg
    33601 tatcagtatg atcattgaga gtgtgggtgg cttcttattc tttatcttac tatataggag
    33661 gtctcgtcag tgaaactgga aaacattgac aaatccattc aaaaacagga tattttgcaa
    33721 ggcatttcgc ttgaagtcag tcctcaaaaa ctgacagcct ttattggtcc aaatggtgct
    33781 ggaaaatcga ctctcctctc catcatgagc agactaacca agaaagatca gggagttctc
    33841 agtatcaaag gacgtgaaat cgagagctgg aattcgcaag aactggccca agaactaacc
    33901 atcctaaaac agaaaatcaa ttaccaagcc aaattgactg ttgaagaact ggtcagtttt
    33961 ggacgttttc cctacagccg aggtcgactt agatcagaag actgggaaaa aatccgagaa
    34021 actctgaact atttggaact gaccaactta aaagaccgct acatcaatag cctgtcaggg
    34081 gggcaactcc agcgcgtctt tatcgctatg gtactggccc aggatacgga ctttatcttg
    34141 ctggacgaac cactcaacaa tctcgatatc aagcaaagcg tcagcatgat gcagattctt
    34201 cgacgactgg tggaggaact cggcaagacc attatcatcg tcctccacga tatcaacatg
    34261 gccagtcagt atgcagatga aattgtcgcc ttcaaggacg gccaggtctt tagcaaggga
    34321 agaaccgatc aaatcatgca ggctgacctg ctcagtcaac tttatgagat tcccatcacg
    34381 ctagctgata tcaataacaa aaagatctgt atctatagct agtaacataa aagctcaagt
    34441 tagagaacct tcagtctctt agtcaataag attaagagac tccctaaatc gttatcacat
    34501 tttaaaaagg agaaattatg aaaacatccc ttaaacttta tttcactgcc ctagtggcca
    34561 gcttcttgct cctacttggt gcatgtagta caaactcaag cactagtcag acagagacca
    34621 gtagctctgc tccaacagag ataaccatta aaagttcact ggacgaggtc aaactttcca
    34681 aagttcctga aaagattgtg acctttgacc tcggcgctgc agatactatt cgcgctttag
    34741 gatttgaaaa aaatatcgtc ggaatgccta caaaaactgt tccgacttat ctaaaagacc
    34801 tagtgggaac tgtcaaaaat gttggttcta tgaaagaacc tgatttagaa gctatcgccg
    34861 cccttgagcc tgatttgatt atcgcttcac cacgtacaca aaaattcgta gacaaattca
    34921 aagaaatcgc cccaaccgtt ctcttccaag caagcaagga tgactactgg acttctacca
    34981 aggctaatat cgaatcctta gcaagtgcct tcggcgaaac tagtacacaa aaagccaagg
    35041 aagaattggc caagctagac aagagcatcc aagaagtcgc tactaaaaat gaaagctctg
    35101 acaaaaaagc ccttgcgatc ctccttaatg aaggaaaaat ggcagccttt ggtgccaaat
    35161 ctcgtttctc tttcttgtac caaaccttga aattcaaacc aactgataca aaatttgaag
    35221 actcacgcca cggacaagaa gtcagctttg aaagtgtcaa agaaatcaac cctgacatcc
    35281 tctttgtcat caaccgtacc cttgccatcg gtggggacaa ctctagcaac gacggtgtcc
    35341 tagaaaatgc ccttatcgct gaaacacctg ctgctaaaaa tggtaagatt atccaactaa
    35401 caccagacct ctggtatcta agcggaggcg gacttgaatc aacaaaactc atgattgaag
    35461 acatacaaaa agctttgaaa taagccactt caaactcaat ttaatactca atgaaaatca
    35521 aagagcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag gttgcagatg
    35581 aaagctgacg cggtttgaag ggattttcga agagtataaa attttgacat tctaaaacgc
    35641 atcctatcaa gttcactcaa acctgatagg atgcgttttt atcattttga aatctattta
    35701 ccccacctca ttccccttct tgatttcgtt taagggaaaa gtggtctgga acggggtcct
    35761 tacctgtttt cgaccaggga tgacaacgta aaatccgagc caagcccatc aatactccct
    35821 taaaaccatg tttttcaata gcctgaatca tgtagttgga acaagtcaga tcaaagcgac
    35881 aagagggtgg aaagactggt gagataaaac gttggtaaaa gcgcacaggc gctattaaaa
    35941 ttcgtttcat tatttcttag ttacagccat ggtgtgtagt tggctgattt cttttttatt
    36001 aagacgacgg gattctcctg gacggagtcc tgtcaagtct aggtgtccga aacgagtccg
    36061 agacaactta tctacttgga gaccaacagc ttcaaacatc tttttaacct gatggttacg
    36121 cccttcatgg atggtcaact gcaccacaga gcgatttttg actgggtcca ctttgagaat
    36181 ttcataaaca gctggcttgg ttttcttacc atcaatctca agaccacggg tcaaggggcg
    36241 aagattgtcc ttattggcca cacctttaac acgcgcgaca taaaccttgt caatctcatt
    36301 acgagggtga atcatctcgt ctgtaaagtc cccatcatta gtcaaaatca agacacctga
    36361 tgtatcccag tccaaacgac ccacagggta aatacgttct ttgacattgg gcaagaggtc
    36421 gacaaccgtc ttgcgaccct tatcatctgt cacactggaa atcacaccgc gtggtttgtt
    36481 aagcagatag tagacctttt cttcgttgta gataggttga ccttcaactt cgaccttgtc
    36541 gcctgacttg atagtggttg ctagttcacg caccacttgg ccgttaaccg tcaccaaacc
    36601 ttgcttgatc agctcttctg cttttctcct actggccaca cctgcgtggg caatatactt
    36661 attgattctc atcttcttct atcctttcac caaataattg gctttcttgg gcttgaatct
    36721 caagctcatc aatcactggt aattcttcta aatggtttat ccccatgtaa tctaggaaat
    36781 aatccgtagt cacatagagg ttggggcgcc ccaatacttc ctttttcccg tcttccttta
    36841 tcaggtcaaa agcctgcaac tttgccaagg ctccactcga gttaacccca cggatggcat
    36901 caatttctat ccgcgtaatc ggctgtttgt aggcaataat ggacaaggtc tcaagggcag
    36961 cccgagacaa gctctggttg ataggcgcct tagagtattc cttcaaaatc tctgcaaatt
    37021 gaggcttggt caccaatcta taagcaccac ttgtctcaat caaagccaaa ctggaatctg
    37081 ggtccttttc atacttctgg gctaattttc ctaaactttg ctggatgcct gtcggtggca
    37141 gagagaggag ttcagctaac tggcggaccc gaatcccatc ttcacccgct acaaacaaga
    37201 gcgcttctat ttttgctaaa gtactcatct ttcctctcta tcaagtctag ctttgaggca
    37261 cttgactttc ttccttcttt tccatgagat agatatctcc aaaactctcc tcttgcacga
    37321 ggatcagctc ctgggttttg attaactcta gggttgccaa aaagagggtg atgacctctt
    37381 ggacattctg ggcttccttg aacaaatcct gcaagcgcaa ttgatctcgt ccaatcaagg
    37441 actctttcac gataatcatc atgtcctcaa tcttatactc atcccgcaag atcgtcgtgt
    37501 gattttgtgc aaactcctct tttttcttgg ctaggatatt tgaaaaagcc aaaaagaggt
    37561 caatggtcgt cttgtcatgc acaagctccg catcttcgta aatcaactct gtcggcgctt
    37621 tggaataata ctgggcccgt tcttggtgct tggcttccaa gtgctcaccc aagagcttga
    37681 acttgcgata ttcttcgatt tgagagagga ggtcctgctc caggtcatcc cccaagtctg
    37741 tcacttctgc taccttcgga aggagtttac gactcttaat cagcatgagc tgactagcca
    37801 tgaccatgta ctcacccgtc acttccagac gcatggcctg cagggttgag acataggcta
    37861 gatactgttc gatgacttcc gtaatgggca catcgtagat atccatctgg tacttagaaa
    37921 ccagatgcaa gagcaagtcc aggggtcctt caaaatcttt taatttaata tccattatct
    37981 atatttttct aaggtcagga ctgtttttaa tcctaatttt tttgcaattt cgtacaaatc
    38041 gaccttgttt tctatttgtc ttagaataaa ctgttcacgt aagacttgag ctgataagga
    38101 tggaaaacct ttctccttga caaaagattc taactgacga aaggcccact gacgagaata
    38161 gggtttctct cctctttcaa aaagataggt ctgccccatc aagggttcca attctgaaag
    38221 caaggccgtg ggaatggtga caatcctctg ttgggaagcc ttgctgattc gcaacacctg
    38281 aaaatccaga ttgatgtccg caaccttgat ggctaaaatc tcactgggca agagccccat
    38341 ttctaggatt aagagcgcta gcaagcggcc ctctggatgg tcgctttcct gccaaaaaga
    38401 gtctaggtat agaatctctg gcttttccgt cttcttttca gcttgtttgg ctaattccaa
    38461 gcggtaaaag ctgtccacct ctcctttttg atagagaaag tatagaaatt ggttacaggc
    38521 cgaaatcttt cgcttctgga cgctgatttt tagattggct agctgggctt ggtaaatctt
    38581 gagactggtc tcagaaatcc gctcacctac catgtctaaa aattgctcca aatcatactt
    38641 ataggactgc ttggaattga cagacaagcc ctgcttttcc tctaaaaagg ctgaaatcct
    38701 gtctctcatt ggcatcgaat ctcatattcc ttactaaagt catgcaagag ggcattaacg
    38761 gtcttgagga tggacttgcg cgtaataatc ccttggaaaa taccctctgc atccacaacc
    38821 ggtaagaagg actcatctac tagcttgtgc aagacctccg taatggtgaa atcaggcgaa
    38881 acaaccgcta cgtccgtttt tgtcatatga acgatatccg tatccgccat gatttcttgg
    38941 ctcaagtcat gctccatctg ataagccata atatctctga gtccaatcgt cccaacaaac
    39001 tgtttttcat ctgtcacaac gggaacacgg gtataggtca tctgactgag caagagggtc
    39061 gcatgatccg cattgtgggt atcaatcaac acagctagat ttttagcagg ggtcaaaaaa
    39121 gtttcctcct gccccaacaa gaaagtctca aactccttgg caatcatcgg ctaaactcct
    39181 tggacaaacc tggatacacc tcgtgatctc gtgtcaaaaa gtccactttg aagtaactat
    39241 catcaatctc cacacgagca tagagacatt ctctgatggt acctcgtggt tgactgatag
    39301 aacctggatt tagaaagagg atcttgcctt ccaaccaagc acttggcaca tgcaagtgac
    39361 catagaggca gatagcggcc tcttcctcct gagcccagta gtccaacttt tgaaagttga
    39421 aattgatgtc aaacaagtga ccatgagttt ggataatctt ggtcgaacca agctcagtca
    39481 ccagacgttc tgggtagccg gcgtagaagt ccatgttccc tttaacaacg cggatgccct
    39541 cccaaagtgg agaatccgga cgtagttcag aatcgccgtt atgaaaaacg gcatcgactt
    39601 tgcccacata gcgatcacgg acttcttcca caatcaagct atcgccatgg gaatcgctca
    39661 ttacaatgat ggtttgcttt gccatgatgg aaatacctcc aaaagtttct taacggctaa
    39721 ggcacggtga gattgactat ttttttcttc cagggttaat tcagctgatg actcacctgt
    39781 ttctcctaca aggaagaggg gatcatagcc aaagccattt tcacccttag gttcaaagtt
    39841 aatataacct gaccagtctg cttcaacaac taaactttcc ttatttgggc tggctacgac
    39901 tagggttgtg tggaactgag ccgagcggtc cttgagttca aagaccatgg ccaattcgtg
    39961 caagagtttg gcattatttt cacggtcagt tgctcccaca cctgcgaaac gagctgacca
    40021 gacgcctggt aagccaccaa ggacatcgac tttgagacca gaatcatctg ccaaaaccat
    40081 cttgcccgtt aattgagaaa tggtttctgc cttaaggcgg gcattttctt caaaggtcat
    40141 acctgtttct gctacttcag gcaggtcagg gtagtcatta agattttcca catcgtagcc
    40201 taacttatca aagatagctc ggaattcctt ggttttacct tcgttacgag tcgcaatcaa
    40261 caaggtttct ctgaccttgc ttgtctcaaa gaaatcatga acattgaccc cttctttagg
    40321 caattctaca tacaagagtt gcccattttc aaccaagagc agggccccat gacgttgaat
    40381 aacttccaag tttcgtccca tttcttgatt aagcatgtct accacaaagg agaacaaacg
    40441 gtaggtagaa ccatagcgta aaacagtaac tgaaagcggg aaaccatact cttcatctcc
    40501 aaatattttg gagaattcaa acagaggaaa atctgtctta tagtcgctca aactgttaac
    40561 gccaccaaaa atactataag acccaacata ccagtcctgg tcatccttat attcataaat
    40621 tttatttgtc ataattctac atgctccaca tgaatctctt tttccagcca ttcttcacca
    40681 atttgtgcaa aactttggct actggctgtt gtgtaaaaac ggtgatggag tggtccagca
    40741 tcgcgaccac gattgatttc aaaataattg agtaagactg agatatcccg tacgcactct
    40801 gccccactat cgatgagctg aacctttggc cccatcacat tttggataat agggcgaagg
    40861 agtggataat gagtacagcc caaaatcagg ctatccacct ttccaaccaa gggacgcagg
    40921 gtttcataga ccaccttctt ggtaacactg gttgacaggg cacctgactc aaccaaggga
    40981 gcaaacttgg gacaggccaa gctctccacc tgtaagtcgg gatccagatc atggattttc
    41041 tgacggtata tgtctgattg taccgtcatg ggcgttccaa tcactccgat tttcccacct
    41101 tgactggact tgatggctgc cgaagctcct ggcaaaatta cacccaagac aggaatatct
    41161 agttgagcct tgatttcttc ccagacgacc gcagtcgcag tgttacaagc aatgacaatc
    41221 attttgacat ccttggtcaa gagaaagttg accagctgcc aagtatattc acgaatttgc
    41281 tcagcaggac gggggccata gggcgcccgc gccgaatctc caatatagac gatttcttca
    41341 tggggaagct ggcgcatgag ctcgcgcaca acggtcaagc ccccgacacc cgaatccaaa
    41401 aaaccaattg gtcgattatc catacagtct tctttctagt cttttttctg attgatcgtt
    41461 cattatgatt ccttgtactg aacgaactga ccgacagctt gatagaatgt caactacctc
    41521 tctcttaatc ataatcaaat atcaatagaa tgcaaggaaa aagtctcatc cctaaaccat
    41581 aaccaacata gtgagaagtc tggaactttc atcccagact tttccttatt tattttttct
    41641 ttttattgtt agcaagggct gccttttgtt ggcggatgat ttggtggtaa acttgttgta
    41701 ccttagcttc gcttggtttt tgaccatttg cactcaaaag agtacgaact gcttcagcat
    41761 tcaaacgtgg gttgtcagca aattcttttt cgatttgctt acgaaccaag tacattcctc
    41821 caagagctcc tcctagaaaa gctagcacaa tcaatacaat tgctaaaagt aaatccatca
    41881 tttttctcct gtttcttttt gagtcccttt cattatacca caaactagcc accctgacca
    41941 gtttgttcta cactttcaag gatggaatag acagcaaaaa gaaccctgct tttctgaaaa
    42001 agaggtctcc ttgctaagtt taatttacat aaatagccag tgtttgatag ggttttagta
    42061 gaattttctc agacacttct gcatcttcat agtttgaaat caaaatctgt ccattttggt
    42121 agactgctgg caagtcgatt tccacttctt tagcataaaa gttattgagc actagtaact
    42181 tttgatcctc aaactggcgt tcaaaagcgt agacttgttt gctatcttca aaggctggtt
    42241 tgtaacttcc ttctgaaatg attggcattt ccttacgcag tcgaatcaag tcttgataga
    42301 aggtaaaaat cggaccctgg atttcatttt ctacattgat gtctttatag gatttaccag
    42361 ctttcaacca aggagtgcct gttgaaaatc ctgcattttc cgaagcatcc cactgcatgg
    42421 gaatgcgtga attatcacgc gacttagctt gaataatctg gaaggcttct tgctgactct
    42481 ttccttcttc taggagcatc tgataggcat taagcgattc gacatccacg taatcagcca
    42541 tagaatcata gtctgggtca atcatcccga tttcctcacc catgtagata taaggtgtcc
    42601 cacgtgacag gtgaatgctg gctgctagca tagtggctcc ttccttgcgg aagttttgaa
    42661 tatcgacaaa acggttcaag gcacgtggtt gatcgtgatt gttccaaaag agggcactcc
    42721 aaccgtcttt atcactcatt tccttacccc aactatggta aagactcttc aactcttcaa
    42781 aatcaaaggg agccaaggtc cacttttgtc catccttata gtccaccttg aggtgatgaa
    42841 aattaaaggt catggataat tcctgacgat caggcgacga atagaggaca cagttttcca
    42901 tggtggtaga agacatttcc ccaactgtca taaagctatc gtcagatcca aaagtggctt
    42961 ggttcatcat acgcaaatag ttatgaacga tgggtttgtc tgtataagct ggcttccctt
    43021 cattttcagg acagtccact gaaacctcgt ccttaccgat caaattgatc acatcaaatc
    43081 gaaaaccttt gacacccttg tcgcgccaga aattaacaac cttgaaaagc tccttacgga
    43141 cattgggatt gcgccagtta aggtcagcct gggtctcatc aaataggtga agatagtatt
    43201 tcccagtatc cccgaaaggc gcccatgcag aaccaccaaa cttagactgc caatctgttg
    43261 gttggtcttg gatgaagaaa aagtcttgat aatacttatc accagctagg gctttctgaa
    43321 accattcatg ctctgtcgaa caatgattaa gtaccatgtc cagcataaag tcaatcttgt
    43381 gctctttacc gacacacacc atttcctcaa aatcagccat atcaccaaaa agaggatcca
    43441 ctgccatata atctgaaata tcgtaaccat tatcccgttg agggcttgga tagaatggat
    43501 tgagccagac catatccaca cctagtttgg ctaaataggg aattttttcg ataatcccac
    43561 ggaaatcccc aataccgttt tcagtggtgt ctttgtaaga ttttggatag atttgataga
    43621 ctacttttcc tttatcaagt gtcatctgtt tctccttttc tgataaaagg gaggaagcag
    43681 tcttccgtcc ctatttgtgc tatttcaatt atactcaatg aaaatcaaag aacaaactag
    43741 gaagctagcc acaggttgct caaaacacta ttttgaggtt gcagatagag ctgacgtggt
    43801 ttgaagagat tttcgaagag tattagattc gtgtagcgac catgagagat gctccagctt
    43861 ggatcgttgt cggataagtt ccagtaatag tcgctgtata agcatcttgg ttggtgatga
    43921 taacaggagt ttctgtcacc agacctgcag ccttaatgac atccatatca aaacgaatca
    43981 gttgctggcc aactataacg tgatctcctt ggactacaag actttcaaaa cctttgccat
    44041 caagacctac tgtatccata ccgatgtgga tgagcaattc aactccctcg tcagagacaa
    44101 tgccgatggc atgcttggta gggaaaagaa ccgtcactgt tccattaact ggagaggtca
    44161 actcaccttg gcttggttca atgaccagac cttgccccat gacacctgat gcaaaaacag
    44221 gatccgtcgc ttgactcaat tctttcactt ggccagttag tgggctgata atttctaccg
    44281 aagtaagttc tactggttca tggctcacaa attctgcttc ttcttgagca acgaattctg
    44341 cctgcaagtt cgtatcgccc tctatttttg tgaagagacc agccttgcga aagaagaaag
    44401 tcaagagcat tggaacaaca atcgcaacta gcatagttcc tgcaaatggc agcatgtatt
    44461 gaggttgaat agagagaata cctggcaaac caccgatacc aatagaagcc gcagttacat
    44521 taaaagtaac ggataacatg cctgcaaggg ctgaaccagt catcccagca acaaatggat
    44581 aaatatattt tacgttaacc ccaaaaagag ctggttctgt aacaccgaga taggctgaaa
    44641 tggttgcagg aagtgaaacc tgagcctcac gctcatcatg gcgatgcatg aaataatagg
    44701 caaacacggc tgagccttga gcaatattag aaagagcaat cataggccag agggcagtgc
    44761 caccagcatc cgcaatcaat tgtgtatcaa tggcattggt catgtggtgc agacctgtga
    44821 tgacaaatgg agcgtagagg gcaccaaaaa ttgcaccgaa gagccatttt acaggacccg
    44881 ttaaacctgc caatacaact gatgaaagtc cttgtccaat tgtccaaccg attggcccca
    44941 agacagtatg agccaaaatc aaggctggaa tcaatgacaa aaaaggtaca aaaatcatgg
    45001 aaatgacttc tgggatatgt ttgcgccaaa aaatttcaag ataagacaga ctcaaacctg
    45061 caagcaaggc tgggataact tgggcttggt aaccaatacg attaacagta aaataaccaa
    45121 aattccaaac ccagtttgct gcgatatcag ctgctggcgt tgaagcaacc gcataggcat
    45181 tgagcaactg aggcgatacc aaacagattc cgagaacaat tcccaaaatt tggctggttc
    45241 ccatcttacg agaaacagac caagtaatcc ctactggtaa gaactggaag atagcttcac
    45301 caggcaacca gaggaagtga ttgacacctg cccaaaactg agaggattct gtgatggtct
    45361 tgccatccaa catcgaccaa tggacacctt ccaagacatt acggaaaccg aggatcaatc
    45421 ctccgactat caaggctgga ataatcggag taaaaatctc cgccagagtg gtcataacac
    45481 gttggaccac gttttgatta ctcttagctg cagacttggc tgcttctttg gaaacaccct
    45541 caatacctga aacggctgta aaatcattat aaaagatggg cacgtcattt ccaatgatta
    45601 cctgaaattg acctgcattt gtaaaagttc ctttaacagc tggaattgac tcgatagctt
    45661 taacattagc cttcttatca tctcctaaaa caaagcgcat ccgtgtcgca cagtgagtta
    45721 cggcagtcac attttctttg cctccaattg cctgaagcag atctttggct tcttgttcaa
    45781 attttcccat ttgattctcc ttatacttgt caaagcaagt ttgatttgat aagtatattg
    45841 taaacgatac caaacttgtc tgcaacttgt ttggtataaa aagggtgttt ttttgtaaat
    45901 tttctagcac ttgtatggta aaatagatac aggtgttcat taaactagac taaaaaccta
    45961 tttaagcagg caaaatgaag aaataccaac aattatttaa gcaaatccaa gaaaccattc
    46021 aaaacgagac ttacgctgtc ggagatttcc ttcctagcga gcacgacctt atggagcaat
    46081 atcaagtgag tcgtgatacc gtccgaaagg ccctgtctct cctccaagag gaaggattga
    46141 tcaaaaagat aagagggcaa ggttctcaag tcgtcaaaga agaaaccgtc aatttccctg
    46201 tatccaacct aaccagctac caagaactag ttaaagaact tggactgcgc tctaaaacca
    46261 acgtggtcag tctggacaag attattattg ataaaaaatc ctcactgata accggtttcc
    46321 cagagtttcg gatggtttgg aaggtggtcc gccagcgtgt ggtggatgat ctggtatccg
    46381 ttctggatac ggactatctg gatatggaac taattccaaa tctcactcgc caaattgctg
    46441 agcagtctat ctattcttat atagaaaatg gcctcaaact ccttattgat tatgctcaga
    46501 aggaaatcac cattgaccac tcaagcgacc gagacaagat tctcatggac attggcaaag
    46561 acccttatgt cgtttcgatt aaatcaaaag tctatctcca agacggacgc caatttcagt
    46621 ttaccgaaag tcgccataag ttagagaaat ttagatttgt agattttgca aaacgcaaga
    46681 aataaaagac tgagacacca gatctcagcc tttttcggct ctataatatt tgtagtgggt
    46741 aaccccccta tggatattat ggagcctatt tt
//
LOCUS       DAVKXA010000011        43398 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKXA010000011 DAVKXA010000000
VERSION     DAVKXA010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.011"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..218)
                     /locus_tag="VW883_000650"
     CDS             complement(<1..218)
                     /locus_tag="VW883_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273829.1"
                     /translation="MLINRLAILLAERSMSGARLASDTGIAQSTISKITSNKSKQVDY
                     ETVNKICNTLGVTSDDFFDYSPIDYEIK"
     gene            379..582
                     /locus_tag="VW883_000651"
     CDS             379..582
                     /locus_tag="VW883_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273830.1"
                     /translation="MLKNNLLIVFAEKKTNASKVSNETGIAESTISNLTNNKTDVKLS
                     TLIKLCNALKVRLSDLIEFSPEN"
     gene            597..1226
                     /locus_tag="VW883_000652"
     CDS             597..1226
                     /locus_tag="VW883_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV0273831.1"
                     /translation="MELVYMDGKKEPYTTSEIIAECAGVTHHTIQELLRKHKADFESY
                     GIIAFEMRKLDGRGRPMKIYRLNEQQATLLITYLKNTEPVRRFKMNLVKAFFEMREEL
                     SKFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDRNAKQLREERGGY
                     NGIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            1661..2113
                     /locus_tag="VW883_000653"
     CDS             1661..2113
                     /locus_tag="VW883_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273832.1"
                     /translation="MEETAYENLTRRIDRISAEMREIGEKTGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSYKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            2110..2310
                     /locus_tag="VW883_000654"
     CDS             2110..2310
                     /locus_tag="VW883_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273833.1"
                     /translation="MTLDLDNMTQAEFDKQMAEIKERNPNLFQFIADFVDRKVTPKEV
                     DEFLKMGRSDQVDYIKNYKARA"
     gene            2312..2527
                     /locus_tag="VW883_000655"
     CDS             2312..2527
                     /locus_tag="VW883_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273834.1"
                     /translation="MNELDLTNTQAVISMVVLIGLLLYLNHRDRKKSAQFERENQQTI
                     ETPSEDLSPDYGRYIQLAGVRVYGGMK"
     gene            2524..2817
                     /locus_tag="VW883_000656"
     CDS             2524..2817
                     /locus_tag="VW883_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273835.1"
                     /translation="MSYTMNLYPDIEKISDETYFTREIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFLNKSKEEEELNESIRE"
     gene            2798..3139
                     /locus_tag="VW883_000657"
     CDS             2798..3139
                     /locus_tag="VW883_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0273836.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LIMRYGIPIIGVRHGTFRGYFIPANKEELLDGAKTFYNQIREEEKRLTVLLNADLESY
                     KQLLKGADEYV"
     gene            3132..3413
                     /locus_tag="VW883_000658"
     CDS             3132..3413
                     /locus_tag="VW883_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0273837.1"
                     /translation="MFSLSQESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     GELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            3548..4408
                     /locus_tag="VW883_000659"
     CDS             3548..4408
                     /locus_tag="VW883_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV0273838.1"
                     /translation="MAIYEAKGFQSNLVYPFDKIEPFQYIELFKPLVVPEGANIEEFK
                     RTQAPYCISGKVTPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSTLFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            4452..5930
                     /locus_tag="VW883_000660"
     CDS             4452..5930
                     /locus_tag="VW883_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV0273839.1"
                     /translation="MEVREQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVT
                     EKVAIPQTFTVAKILSEIVTFTFISKSNIADYSLLYIYDLDEGIYTASNDLFNLLCKT
                     FDVRIKPREWPQIKLMVRTLTKIRKPLESSNLIPVQNGIINLETKELFPFSPKYVITS
                     KISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINSNHTRNKFAI
                     FYGDGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYL
                     KNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVP
                     FNADFNGEKEKPWIKNEFLANDEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEEN
                     DYLLSWVKHEYMERGWHELDVVPVFILTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQ
                     LTPNRYSLRKKRVPSEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            6281..6448
                     /locus_tag="VW883_000661"
     CDS             6281..6448
                     /locus_tag="VW883_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273840.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEINDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            6531..7061
                     /locus_tag="VW883_000662"
     CDS             6531..7061
                     /locus_tag="VW883_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273841.1"
                     /translation="MTLKTFSDKAKTFTFTYEFKDLDTAMVAGHALLGYMTGTYEVPS
                     ISITHKDKGTLVAEYVEDHKLNKTFKRICDSFKDYYNQPVDDEAFEERYKRERVLQLK
                     ESEDFENLLEKVTDYELELLDYADRLLSDKPIPMDSMTAFGTLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            7132..7635
                     /locus_tag="VW883_000663"
     CDS             7132..7635
                     /locus_tag="VW883_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273842.1"
                     /translation="MKRLAIETITKPMKLRGISKGIAELDGQRLEIDLDNLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKSTLNRSKTNCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKRDRYHKHYKKFLKYTKKGDRF
                     WLNGLRL"
     gene            9233..9589
                     /locus_tag="VW883_000664"
     CDS             9233..9589
                     /locus_tag="VW883_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0273843.1"
                     /translation="MQLKYQSLESGLLAGSSQFQTRVSTSKTNTAENKLLDTLELRDK
                     IAEQIQAIINERMEAMDMINQLEEIEEWLVLVMIYFNNLPMVKICNDLNFSKVQIYRI
                     RKKAIENLAKVKNANR"
     gene            9576..9914
                     /locus_tag="VW883_000665"
     CDS             9576..9914
                     /locus_tag="VW883_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001121035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273844.1"
                     /translation="MPIDKEETIKQAYKFLKSYHSLVKLSLGGQDGAFEAKAMELLRV
                     IEAFRDNLDDVRHEIFANLFTRRTGERLKLWQIYEALDIDKAEYERLKAEILLDFTKS
                     YCGGVLLKKC"
     gene            10568..13399
                     /gene="uvrA"
                     /locus_tag="VW883_000666"
     CDS             10568..13399
                     /gene="uvrA"
                     /locus_tag="VW883_000666"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0273845.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKIQKDGYVRVRVDGEVYDVTEVLELSKSRQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGYYLKGKLHHE"
     gene            13392..14453
                     /locus_tag="VW883_000667"
     CDS             13392..14453
                     /locus_tag="VW883_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0273846.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGIRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            14585..14983
                     /gene="spx"
                     /locus_tag="VW883_000668"
     CDS             14585..14983
                     /gene="spx"
                     /locus_tag="VW883_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0273847.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            15049..15618
                     /locus_tag="VW883_000669"
     CDS             15049..15618
                     /locus_tag="VW883_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0273848.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGFENLLKNEPSKYISDRLANGATEQ"
     gene            15705..15971
                     /locus_tag="VW883_000670"
     CDS             15705..15971
                     /locus_tag="VW883_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0273849.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            15975..16394
                     /gene="ruvX"
                     /locus_tag="VW883_000671"
     CDS             15975..16394
                     /gene="ruvX"
                     /locus_tag="VW883_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0273850.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            16410..16715
                     /locus_tag="VW883_000672"
     CDS             16410..16715
                     /locus_tag="VW883_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0273851.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            16923..18173
                     /locus_tag="VW883_000673"
     CDS             16923..18173
                     /locus_tag="VW883_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0273852.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLACQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMRERKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLAEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            18170..18712
                     /locus_tag="VW883_000674"
     CDS             18170..18712
                     /locus_tag="VW883_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0273853.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTLDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            18858..20390
                     /gene="cls"
                     /locus_tag="VW883_000675"
     CDS             18858..20390
                     /gene="cls"
                     /locus_tag="VW883_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0273854.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            20468..20611
                     /locus_tag="VW883_000676"
     CDS             20468..20611
                     /locus_tag="VW883_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273855.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            20648..22186
                     /locus_tag="VW883_000677"
     CDS             20648..22186
                     /locus_tag="VW883_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0273856.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSNYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            22306..24513
                     /gene="nrdD"
                     /locus_tag="VW883_000678"
     CDS             22306..24513
                     /gene="nrdD"
                     /locus_tag="VW883_000678"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0273857.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSNQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            24525..24665
                     /locus_tag="VW883_000679"
     CDS             24525..24665
                     /locus_tag="VW883_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273858.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            24709..25215
                     /locus_tag="VW883_000680"
     CDS             24709..25215
                     /locus_tag="VW883_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273859.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAAILANGGIFEDARNGVER
                     YWIEVANE"
     gene            25208..25798
                     /gene="nrdG"
                     /locus_tag="VW883_000681"
     CDS             25208..25798
                     /gene="nrdG"
                     /locus_tag="VW883_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0273860.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            25795..26411
                     /locus_tag="VW883_000682"
                     /pseudo
     CDS             25795..26411
                     /locus_tag="VW883_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            26672..26980
                     /gene="rpsJ"
                     /locus_tag="VW883_000683"
     CDS             26672..26980
                     /gene="rpsJ"
                     /locus_tag="VW883_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0273861.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            27196..27822
                     /gene="rplC"
                     /locus_tag="VW883_000684"
     CDS             27196..27822
                     /gene="rplC"
                     /locus_tag="VW883_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0273862.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            27847..28470
                     /gene="rplD"
                     /locus_tag="VW883_000685"
     CDS             27847..28470
                     /gene="rplD"
                     /locus_tag="VW883_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0273863.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            28470..28766
                     /locus_tag="VW883_000686"
     CDS             28470..28766
                     /locus_tag="VW883_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0273864.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            28784..29617
                     /gene="rplB"
                     /locus_tag="VW883_000687"
     CDS             28784..29617
                     /gene="rplB"
                     /locus_tag="VW883_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0273865.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            29721..30002
                     /gene="rpsS"
                     /locus_tag="VW883_000688"
     CDS             29721..30002
                     /gene="rpsS"
                     /locus_tag="VW883_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0273866.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            30014..30358
                     /gene="rplV"
                     /locus_tag="VW883_000689"
     CDS             30014..30358
                     /gene="rplV"
                     /locus_tag="VW883_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0273867.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            30371..31024
                     /gene="rpsC"
                     /locus_tag="VW883_000690"
     CDS             30371..31024
                     /gene="rpsC"
                     /locus_tag="VW883_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0273868.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            31028..31441
                     /gene="rplP"
                     /locus_tag="VW883_000691"
     CDS             31028..31441
                     /gene="rplP"
                     /locus_tag="VW883_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0273869.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            31451..31657
                     /locus_tag="VW883_000692"
     CDS             31451..31657
                     /locus_tag="VW883_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0273870.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            31682..31942
                     /gene="rpsQ"
                     /locus_tag="VW883_000693"
     CDS             31682..31942
                     /gene="rpsQ"
                     /locus_tag="VW883_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0273871.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            31968..32336
                     /gene="rplN"
                     /locus_tag="VW883_000694"
     CDS             31968..32336
                     /gene="rplN"
                     /locus_tag="VW883_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0273872.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            32414..32719
                     /gene="rplX"
                     /locus_tag="VW883_000695"
     CDS             32414..32719
                     /gene="rplX"
                     /locus_tag="VW883_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0273873.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            32743..33285
                     /gene="rplE"
                     /locus_tag="VW883_000696"
     CDS             32743..33285
                     /gene="rplE"
                     /locus_tag="VW883_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0273874.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            33303..33572
                     /gene="rpsN"
                     /locus_tag="VW883_000697"
     CDS             33303..33572
                     /gene="rpsN"
                     /locus_tag="VW883_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0273875.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            33857..34255
                     /gene="rpsH"
                     /locus_tag="VW883_000698"
     CDS             33857..34255
                     /gene="rpsH"
                     /locus_tag="VW883_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0273876.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            34447..34983
                     /gene="rplF"
                     /locus_tag="VW883_000699"
     CDS             34447..34983
                     /gene="rplF"
                     /locus_tag="VW883_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0273877.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            35067..35423
                     /gene="rplR"
                     /locus_tag="VW883_000700"
     CDS             35067..35423
                     /gene="rplR"
                     /locus_tag="VW883_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0273878.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            35441..35935
                     /gene="rpsE"
                     /locus_tag="VW883_000701"
     CDS             35441..35935
                     /gene="rpsE"
                     /locus_tag="VW883_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0273879.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            35907..36131
                     /gene="rpmD"
                     /locus_tag="VW883_000702"
     CDS             35907..36131
                     /gene="rpmD"
                     /locus_tag="VW883_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0273880.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            36276..36716
                     /gene="rplO"
                     /locus_tag="VW883_000703"
     CDS             36276..36716
                     /gene="rplO"
                     /locus_tag="VW883_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0273881.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            36729..38039
                     /gene="secY"
                     /locus_tag="VW883_000704"
     CDS             36729..38039
                     /gene="secY"
                     /locus_tag="VW883_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0273882.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            38190..38828
                     /locus_tag="VW883_000705"
     CDS             38190..38828
                     /locus_tag="VW883_000705"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0273883.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            38945..39163
                     /gene="infA"
                     /locus_tag="VW883_000706"
     CDS             38945..39163
                     /gene="infA"
                     /locus_tag="VW883_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0273884.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            39188..39304
                     /gene="rpmJ"
                     /locus_tag="VW883_000707"
     CDS             39188..39304
                     /gene="rpmJ"
                     /locus_tag="VW883_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0273885.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            39322..39687
                     /gene="rpsM"
                     /locus_tag="VW883_000708"
     CDS             39322..39687
                     /gene="rpsM"
                     /locus_tag="VW883_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0273886.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            39705..40088
                     /gene="rpsK"
                     /locus_tag="VW883_000709"
     CDS             39705..40088
                     /gene="rpsK"
                     /locus_tag="VW883_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0273887.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            40131..41066
                     /locus_tag="VW883_000710"
     CDS             40131..41066
                     /locus_tag="VW883_000710"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0273888.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            41078..41464
                     /gene="rplQ"
                     /locus_tag="VW883_000711"
     CDS             41078..41464
                     /gene="rplQ"
                     /locus_tag="VW883_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0273889.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            41729..41995
                     /locus_tag="VW883_000712"
     CDS             41729..41995
                     /locus_tag="VW883_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0273890.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            42005..43342
                     /locus_tag="VW883_000713"
     CDS             42005..43342
                     /locus_tag="VW883_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0273891.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
BASE COUNT        13815 a         8027 c         9635 g        11921 t
ORIGIN      
        1 tattttatct cataatctat tggagaataa tcaaaaaaat cgtccgaagt aacccctaaa
       61 gtgttacaga ttttattaac agtttcataa tcaacttgtt ttgatttatt tgaagtaatc
      121 ttagaaattg ttgattgtgc aattcccgta tcacttgcta aacgcgcacc actcattgac
      181 ctttcagcca atagtatagc caatctattt attaacataa taccacctct ttttatttat
      241 tatagcgcac acgctaataa aagtaaaata taaaataata atttaagtgt tgacaatatg
      301 ttttatatgt tgtatcatat cattaaatta gtcattgcgc tataatgatt agttaataaa
      361 aaataataag gagcgcctat gctaaaaaat aacttactaa ttgtttttgc tgaaaaaaag
      421 actaatgcta gtaaagtttc caacgaaaca ggtatagctg agtctacaat ttcaaactta
      481 acaaacaaca aaactgacgt aaagctttct acccttatca agctttgtaa cgctttaaaa
      541 gttcgtttgt ctgatttaat tgaattttca ccagaaaatt agaaaggagc aaaccaatgg
      601 aactagtcta catggacgga aagaaagagc cgtatactac gagtgagatc atcgctgaat
      661 gtgctggagt cactcatcac acaatacaag aacttttaag gaagcataaa gctgattttg
      721 aaagctacgg aattatcgca tttgaaatgc gtaaattaga cggccgaggg agaccaatga
      781 agatatatcg cctaaatgaa caacaagcga ccttgctgat cacttattta aagaatactg
      841 aacctgtacg gcggttcaaa atgaacctag tcaaagcatt ctttgaaatg cgtgaggagc
      901 tttctaagtt ccgtatgcag agggcgctag aaaagccaaa aagaaaaacc ttgcatgaca
      961 gtatagagac atgggaggca aaacccaagc acgcgcatag caccatgaac aacctgctac
     1021 taaaagcagt aactgacagg aacgctaaac agttaaggga agaacgtggg ggctacaatg
     1081 gtattgatag cttgaccagt gacgagctgg agcaatacca ggcatttgag gatatggtaa
     1141 tagccatgat cggcttgaat atgagttacc aagaaatcaa ggctatggca ttcagaaata
     1201 aaaaaacacg ccaaagaagc gcgtgattgc aacaaaaaag gcttaccgag accaatcagc
     1261 aaagcctttc acactatgac taaaacgaat ttaacaaaaa gcaggcaagc tattatcaaa
     1321 gaggttttag taaagattta tacctagatt atagcatatt tagggcaatt tgaccatacg
     1381 gagagcgcca actctttaaa ctggtacttt ctcacgcttt caatttggcg agtctgagcg
     1441 tgaggaatag cgttataaga aacaactcaa aaagccccac gttcagaaat ttggcgaccg
     1501 agagcatgag gctgtagaca agaaaaactg tataagaaac aaccattcaa aatccccaca
     1561 ctcgccatcg ctcaactttg agtgtgagga tatcctggat agtaaaaggc attaaaaagc
     1621 ccttagggca actacacaac atagaaacag aggtaaaaat atggaagaaa cagcatacga
     1681 gaatttaact agacgtatag acagaattag cgcagaaatg cgagaaattg gcgaaaaaac
     1741 tgggcttagt agactttcgt tattggcaaa tcagacaaaa ttcatcaaag aaaatttaca
     1801 ccgtttactt tggattgaac ttcctgaatt gaatgacagc tataaaatcg aggcagtttc
     1861 taaaagcact acgggaatgt ttttccaccc tggtattttt gaaatggacg ctatgcgaca
     1921 agcattcttt aaacgccaag ctatgcactt ttttgagaac gaagcagagc aacaggcgta
     1981 tatagaacat gctgaaaagg agtatttaga ggctactata accttaaaag atattctttt
     2041 taactctaaa aatggaactc agagagtaaa taaaagttgt cttatagaga agtttgagga
     2101 ggcaatgcaa tgacactaga cctagacaac atgacacaag cagaatttga taaacaaatg
     2161 gctgaaatca aggagagaaa tccgaatctc ttccagttta ttgctgattt tgtagataga
     2221 aaggtaacac ccaaagaggt agatgagttt ttgaagatgg gacgaagcga ccaagtggac
     2281 tacatcaaga actataaagc gagggcatga catgaatgaa ttagatttga ccaatacaca
     2341 ggcggtaatc tctatggtgg tactgattgg cttactgctt tatttaaacc accgagaccg
     2401 taaaaaaagc gcccaatttg agcgagaaaa ccaacagacg atagaaacac ctagcgagga
     2461 tttaagccct gattatgggc gttatatcca gcttgcaggg gtaagagttt acggagggat
     2521 gaaatgagtt acacaatgaa tttatacccc gatattgaaa aaatatcaga cgaaacctat
     2581 tttaccagag agatttttct agcaacgtgc ttgaataaca caatcagaat agcagtagcc
     2641 agaggagtgc taacatctca acttttagac aaagaaacta aagaagttgt ttgtaaaacc
     2701 ttggatacaa tcatagaaaa tcaaaaagct attttgcaag gggtagcaag cggacaaata
     2761 acctttttga ataaaagcaa agaagaggag gaactgaatg agtctatcag agaatgacaa
     2821 acgagtatta agactaatca aggtaggtgc tgagaactcc ataacagggg cagaaatcag
     2881 cctgatcact aagttagcag aaagaaccgt gcaagatatt atcagccgtc tgatcatgcg
     2941 ctacggcatt cctatcatcg gggtacgtca tggaacattt agaggatatt ttatcccagc
     3001 taacaaagag gagttactgg acggtgcaaa aacattttac aatcagatac gagaagaaga
     3061 aaagcgccta actgtccttt taaatgctga tttagagagt tataagcaac tactgaaggg
     3121 ggcggacgaa tatgtttagc ctaagccaag aaagcgagca agacctagcg catggcattc
     3181 tggaggtagt ggaaagatac ctggaagcgc gtgatacagt caaaccacga ctgacaggtt
     3241 taatatcagc ccaggaagtc atgggcgagt tagatataaa atacatgaca ctccaaaaat
     3301 gggaaaaagc agggctaaga cggtatcagc caccgctaga agatactagg aaaatctatt
     3361 ataaaatatc tgacatctgg aagtttttgg gggtggaaaa tggcaaggta tagtattcat
     3421 ccggcagata ataaagggca ttatcacaat attaaatttt acaaagagcg caggccaacc
     3481 ctagaccagc taaaggaaca gcaaaggctt aaaaagctga agaaaaaacg tagaaagggg
     3541 cgataatgtg gcaatttatg aggctaaagg ctttcagagt aatcttgtct atccatttga
     3601 taaaattgag ccgttccagt acattgaact ctttaagcct ttggtagtcc ctgaaggggc
     3661 aaacattgaa gaatttaaac gtacacaagc gccctactgt atcagtggga aagtgacacc
     3721 agaaaagaat ggcagttaca agcgaaacaa ctccagtcta atctatcggg atttgatttt
     3781 ccttgattat gacgatatac aggggacgac tgaggacttc atagaagccg tttctagcac
     3841 tttgtttggc tactcttata tcttataccc gactatcaaa catagcatag aaaagccccg
     3901 ttttcgcctt gtggtgaaat ctaacaacgt gatgaacgag gcaacctata agcaggtagt
     3961 aaaagagatt gctgacaaga ttgggctacc ctttgacatg gccagtttaa cctggtcaca
     4021 actccaaggg ctaccagtaa caacaggcga cccagcaact tatcaaaaga ttgtagagca
     4081 tggacttgat tatccagtcc ccaaggttga accaagagcg aagcaaggaa ctactgagcg
     4141 ttataaacct agagtaagtg gccagaggtc aatgactatg aggattattg acacgctttt
     4201 caacggattt ggagacgaag gagggcgcaa cgtagcgctg acacgctttg tgggattact
     4261 cttcaataag tgggttgatt gtgacctaga gaccgcctat gaactgacaa agatagcaaa
     4321 tagcgtgaca gttgaaccat tgcctattga agagctagac cgcactttta gcagtatagc
     4381 acgggctgag tatagaaaga gaggttagaa ccatagaact agaagaatta gcaaacctaa
     4441 aaagtgaaat catggaggtc agagagcaag aacaccctcc tagaacgatg aaggagcttg
     4501 aaaatcgtat ctttaaagct ggtgaagaat ggcgggcaga acataccgaa actaaggtaa
     4561 atgagaccac aggggacgtt actgaaaagg ttgccatacc tcagacattc actgtagcta
     4621 aaatactgag cgagattgtc acgtttactt ttatcagcaa gagcaatata gctgattata
     4681 gtctactcta tatctacgat ttagacgagg gtatctatac agctagtaat gatctattta
     4741 atctattgtg taagactttt gatgtgagaa ttaaacccag agagtggccg cagattaagt
     4801 taatggttag aacactaaca aagatacgaa aacctttaga aagttccaac ctcattcccg
     4861 tacagaacgg aattatcaac ttagaaacta aggagctatt cccctttagt cctaagtatg
     4921 taattacaag caagataagc acggcatacc acgcgcctaa acgagtccca acagatagag
     4981 agggaaaaac ttttgatgat tggctaaact caatcgcttg taatgatagt gagctagtga
     5041 cactgttttg gcaaattatc cttgaagcta tcaactctaa ccatacccga aataagtttg
     5101 ctatcttcta cggggacggt aacaatggta aagggacatt tcagcgcttt cttatcaatc
     5161 tgatagggga aagcaatata tcagccttaa aacctgcaca gtttgctgaa aagcataact
     5221 tagaaaccct ggtaggtaaa gtttgtaata tcggagatga agccccaaat gaatacttga
     5281 aaaatccgtc tgatttaatg agtatcacta gtggcgatac agtactggtc aaccccaaag
     5341 gacgcccagc ctttgaggct actttcaagt tattcaatat cttttcaggg aattatatcc
     5401 ccaatggtgg caacaagaca aaaggctggt atcgtagaat tatgattgtc ccttttaatg
     5461 ctgactttaa cggggagaag gaaaagcctt ggattaaaaa tgaatttttg gccaatgatg
     5521 aagtattaga gtacgcactt tacaaagcta tcaatcaaga gccttttaca cactttatcg
     5581 aacccaaagc agtcaaaggc cttctagaag aataccagga agaaaatgac tacttgcttt
     5641 catgggttaa acatgaatac atggaaagag gttggcatga gctggacgtg gtacccgttt
     5701 ttatactgac cagatcacta aagcactatg ccgaagatat gggaataccc aaacccaatg
     5761 tttacggggc tggtaaagaa actatcaagc acttacaaca gttgacacct aatcggtatt
     5821 ctctaagaaa gaaaagagtt ccttcagaag attttgaaaa actagaggca tgggacgttg
     5881 acaagataaa aatgcggaca cctcaacact ctatcactaa acaagaataa gtgtgacgtt
     5941 ctttttttgc ttaaaccctt gataatactg attttcttaa aaaaagtgtg acgttgtgtg
     6001 acgttctcaa aaaagaaggt cacacccctt gaagccttga tatatctagc tttaggggaa
     6061 taggtgtgac gttgtgacat tctttccaac tcttatatat agagaaaaat gcagtattta
     6121 tatataggaa cgataaaaca aaagaacgtc acagggtcac aggggtggtg aaacacctag
     6181 agcctcaagg gtttgaacgt gtgacgttct ttgtcacaga aggtcacaga acacgaaaaa
     6241 tattacataa tttaccttaa aataaagaaa tgacaacaac atgaaagtta aactatttga
     6301 atatactaga cgatgggaaa aagaagactt tgagaaagag atcaatgact tcatggcaac
     6361 tgttgaagtg ctggacgtta aattttctgg tacaccatct agtgaatcct ttaattcggt
     6421 ggctatcgta ttggtattat acagataaca aaatggggta gatagtaccg acccccttgt
     6481 aatggtgtaa ctactagtga cacccttaaa acagaaagag gaaaaacaac atgacattaa
     6541 aaacattttc ggataaagcc aaaacattta ctttcactta cgaatttaaa gacctagata
     6601 ctgctatggt agcaggtcac gcgctactgg gatatatgac tgggacttat gaagtaccat
     6661 ctatttcaat aactcacaag gataaaggga cgcttgtcgc tgagtatgtg gaagatcaca
     6721 agctaaacaa gactttcaag cgtatttgtg acagtttcaa agactattac aaccaaccag
     6781 tggacgatga agcatttgaa gaacgttata aacgggagcg cgtgctccaa ctcaaagagt
     6841 cagaggactt tgagaacttg ctggaaaaag taacagacta cgagctggaa ctattagact
     6901 atgctgatcg cttgctttct gataagccta tccctatgga ctctatgacc gcttttggta
     6961 cgttggaaat gctgggcgat gaaagtatta gcctactcca aaagttggac gtagagggcg
     7021 aatataaagg ccttgctggt tatacagagc atttgaagta gaacacaggg gagcaatccc
     7081 ctttttgtta tcaagtcaat agttttgggt ttttccatat agggggaaat aatgaagcgg
     7141 ttagcaatag aaacaatcac taaaccaatg aagctgagag gaatatctaa gggtatagct
     7201 gagttggacg gtcaacgttt agagattgat ttggataatt taatgattga ttttggtgga
     7261 gagtcatttg aattagacag aatagcagga actaagggag gtaatagata tttctttctt
     7321 tgccctgatt gtgggagacg gtgcaggttg ctttataaac ggtatttata ttttagttgc
     7381 ggtacttgtc tagatatcca caagagcacc ctgaaccgta gtaaaacgaa ttgccaatac
     7441 tactgggagc ttgcactaaa agaagccaga aaggtagaac cagggtggag tcctagacgt
     7501 ggtggatata tgtttgatag tttccctgaa agaccaaagt atatgaagcg cgacaggtat
     7561 cacaagcact ataagaagtt tttgaagtat actaaaaaag gagatagatt ttggctgaat
     7621 ggtttgagat tgtaggacaa tatgaagtag tgtgcaattt acaaaacaaa caaatactac
     7681 atattagacg gtttgaatgt taaaaaagct agatatgtca aggatttaag taagtagagc
     7741 gttccaaaaa atggtgcggt aagcgttccg aaaaatggta aggttttggt aaggttgcat
     7801 atataaaaag tataagatta gtataaggtt gtgtatttta aaatactaag gttttacaaa
     7861 ggtacagggc tttttttcta gtgatataac cacaaggata ccacaaggta gagagtttta
     7921 ccgagggtta gaaaaggtga gattttgctt aggtagtggc agtaaatatg cctgataaat
     7981 ggaataaaga tagttgtaag attagagtaa gatgttatta gtaatttgat tagtagatac
     8041 atttaccttt ctctaagtgt tatgatcaaa ttgaattagt cagtaatcaa caatactttg
     8101 tgttgattgc attctttatt gattgatata atcaaatcga taacaataga tgaatgaaat
     8161 gcaatgttag caatagttaa caaatgattt ctctttctct tttatgtttg aatgacatga
     8221 gattgaacta ctggaaaacg ataaggggat aaaaaagtat gcaaataccc cccttatttt
     8281 tgaacggggg tatataatgt tcggatatag gaacgcgccc cccttctgtg caaaaatttc
     8341 cctttttgaa atgtttttaa tttttgtaga atgcagtatt actaagtgtt tagcttgatt
     8401 ttttgaccga taaagctact ccaattttat aacacagtgg ggctatcttc ctccccacgc
     8461 gcttctatga acttcacact gtcattgtac attttttctc acgggaaagc attgaactcc
     8521 gagcgaacgc cgagaaagtg gatatatcct cctatcattt atcaagcaga taagggcgac
     8581 aataagcctt cttaattgct tacaaaacga tagggagtta agacgaattt aaaagctcct
     8641 tattttcgtt tttctccttg tcaaatagta aggaaataag acaggaaata acatcgctta
     8701 ttttgatttt gctccctgaa aaactgtaag gagataagga gacttattag cttccttaat
     8761 ttggattttc tccttacaaa atgacaggga aataagaact aaaataactc cccttatttt
     8821 tctacaaaat gataagcaga taagccaata aataacttgc cttaattgct ttcaaacatg
     8881 aacaagtatg aacatattcc accagtcgtt gaaaatacaa aaagccaagg cttaccacct
     8941 cagaatgatt aggttttggt taggttttac atttaaaaat agcaaggtac aggactttat
     9001 tctagagata aaatactaag atttcctaag atacaaatac ttttagagat aaagaacgtt
     9061 aaggagggta taatcgaact cctagaaaac gcaaaaaaag ccagcacagg gctgacttct
     9121 ttataaatta ttccttaaaa ttattatacc ataaaggagt agcaacttga ctattaaaga
     9181 aatagaggaa taactaaaaa gagtaaagaa aggaaatgcc cttatccagg aattgcaact
     9241 taaataccag agtttagaaa gtggactgct tgcaggatct agtcagtttc aaacacgggt
     9301 aagcacaagc aaaaccaata ccgctgaaaa taaactgctt gatactttgg aattaagaga
     9361 taagatagcg gagcagatac aagctattat taatgaacgt atggaagcaa tggatatgat
     9421 aaaccagtta gaagaaatcg aagaatggtt agtgttggta atgatatact ttaataattt
     9481 acctatggtt aaaatctgca atgatttaaa ttttagcaag gtacagattt acagaattag
     9541 gaaaaaagcc attgagaact tggccaaggt gaaaaatgcc aatcgataaa gaagagacga
     9601 taaaacaagc atacaaattt ctaaaaagct atcactcgtt ggttaaactg agcctaggcg
     9661 gtcaagatgg agcatttgaa gccaaagcga tggagctact gcgcgtgatc gaagccttca
     9721 gggacaatct ggacgatgta cgacatgaga tattcgccaa tctctttaca aggcgaactg
     9781 gggagaggtt aaagctatgg cagatatacg aggcactaga cattgataag gctgagtatg
     9841 agcgtctcaa ggctgagata ctgctagact ttactaaaag ctattgtggt ggtgttttgt
     9901 tgaaaaaatg ttgagattta agcgagagaa catggacatt tatggacaca tatcgccagt
     9961 tgttgaacag ctcataaaat gttgtcaggt actaacaagt tcttacacat cccgcccgtc
    10021 gtcgaaaaac taaaaaataa tctctgggtc tgaaaagttc ctacatattc caccagaacg
    10081 gagagttaga agcgtaaatg ttggcaaatg taggctgagg cttcttattc gccccctatt
    10141 ttgctttgtt tcgtactgga caactaaaac accatggata aactacaagc cctcagaaac
    10201 gaatctgggg gcttttgtga ggtcataatc ttataaacca cgcgcttcat ggtataatat
    10261 acctatcagc aaccagcaat aaaaaaagca cgtttgaccg tgctagtttc ttgcctgctg
    10321 aactcgtcaa atcttagccc ttttgtgggg ctttttttgc tccccttttt gcgtactttg
    10381 ggggagcaag tagtaaaaag taatgttagt aatttttatt aaaaagcgcg tgatataagg
    10441 gttaggaagt cctaaggaaa cataaaataa gaagtttttt attatactac aaaatcggcc
    10501 ttttgggtaa tagaatctca ctttttttgg tataatggta agcaataatg gactagaaag
    10561 aacaaagatg caagataaaa ttgtcattca tggggcgcgt gcccataatt taaaaaatat
    10621 tgatgtggag attccgcgag acaagttggt tgtcgtgact ggcttgtcag gttcagggaa
    10681 gtccagtctg gcttttgata ccctctatgc ggagggacaa cgtcgctatg tagagagttt
    10741 gtccgcctac gctcgtcagt tcttgggaaa tatggaaaaa ccagatgtag atgccattga
    10801 tggtctcagc ccagctattt ctatcgacca gaaaacgact agcaaaaacc ctcgctcgac
    10861 ggtgggaaca acgactgaaa tcaatgacta tctgcgtctc ctctacgcgc gtgtggggac
    10921 gccttactgt atcaacgggc atggggctat caaggcttct tctgtggagc aaatcgttga
    10981 taaggttttg gagttacctg aacgccagcg cctgcagatt ttggcccctg tcatccgtaa
    11041 gaaaaaagga cagcataaga gcgttatcga gaagattcag aaagatgggt atgttcgtgt
    11101 ccgtgtggat ggggaagtct atgatgtgac cgaagtgcta gagttgtcca agagcagaca
    11161 acacaatatt gatgtcgtgg ttgaccgtat tgttatcaag gagggcattc gtagtcgtct
    11221 ctttgattcc attgaggctg cccttcgtat cgcagaaggt tatgtgatta tcgacaccat
    11281 ggacgactct gagttgttgt tctctgagca ttatgcctgt ccagtttgtg gatttactgt
    11341 cccagagtta gaacctcgtc tcttctcttt caatgctccc tttggctctt gtagtgagtg
    11401 tgacggcttg gggattaagc tggaggtgga tactgatttg gtagtgccag atgccagcaa
    11461 aaccttacat gagggagcgc tggcaccttg gaatcctatc tcatccaact actatccaaa
    11521 catgttagag caggccatga aagtctttgg agtggctatg gataagcctt ttgaggacct
    11581 gtcagaagaa gataagaact tgattctcta cggctcagat ggtaaggaat tccatttcca
    11641 ttatgaaaat gaatttggtg gtgtgcgcga tatcgacatt ccgtttgagg gagttatcaa
    11701 taatatcaaa cgtcgttacc atgaaaccaa tagcgattac actcgcactc agatgcgtct
    11761 ctacatgaat gagctgacct gcggaacctg tcaaggctat cgtctcaatg accaggcctt
    11821 gtctgtccgt gtgggcggcc agcaagggcc acatattgga gaaatctcag acctgtctat
    11881 cgctgaccac ttggacttgg tgagccagtt aactttgtct gaaaatgaag ccatcattgc
    11941 tcgtcccatt ctcaaggaaa tcaaggatcg tttgaccttc cttaataatg tgggtcttaa
    12001 ctatctaacc ctgtcacgtt cagcaggaac cctttcaggt ggggaaagtc agcgcattcg
    12061 tttggcaacc cagattggtt ccaacctatc aggtgtcctc tatatcctag acgagccgtc
    12121 aatcggtctt caccagagag acaatgaccg cctgattgcc agtctgaaaa agatgcgtga
    12181 cttgggcaat actcttatcg tggtggaaca cgacgaagat accatgcgtg aagctgatta
    12241 tctgattgac gttggtcctg gtgccggtgt ttttggtggt gagattgttg cagcaggtac
    12301 acctaagcaa gtggctcgca acagcaagtc tatcacaggt cagtacttgt caggcaaacg
    12361 tgtcatccca gtaccagaag agcgccgtgt cggaaatggt cgttttattg aagtgatagg
    12421 agcgcgtgag aacaacttgc aaaatgtcac ggctcgcttt ccactaggaa aatttatcgc
    12481 agtgacaggt gtgtcgggtt cagggaaatc gactctaatc aacagcattc tcaaaaaagc
    12541 cattgcccag aagctcaacc gtaattcaga caaacctggt aagtttaaga ctattacagg
    12601 gattgagcat gtcgaccgtt tgattgatat tgaccagagc cctatcggac ggacgccgag
    12661 gtctaaccca gctacctata caggagtttt tgacgatata cgtgaccttt ttgctcagac
    12721 aaatgaagcc aagattcgag gctacaagaa ggggcgcttc agtttcaacg tcaagggagg
    12781 tcgctgtgaa gcttgctcag gtgacgggat tatcaagatt gagatgcact tcttgccaga
    12841 tgtttatgtg gcttgtgaag tttgccacgg aacccgctat aacagtgaaa ccctagaagt
    12901 tcactacaag gaaaagaata tttcgcaggt cttggatatg acggtcaacg atgcggtaga
    12961 atttttccaa cacattccga aaattcaacg caaactccag accatcaagg atgtagggct
    13021 aggctatgtg accttgggac agccagctac caccctttct gggggagaag cccaacgtat
    13081 gaagttagct agcgaactcc acaaacgctc gacaggaaaa tctttctaca ttctggatga
    13141 gccgacgaca gggcttcata cagaggacat tgctcgcctg ctcaaggttt tagctcgctt
    13201 tgtagacgat ggcaatacag tcctcgtcat cgagcacaat ctggatgtta tcaagacggc
    13261 agaccatatc attgacttgg gacctgaggg cggtgtcggt ggtggaacca tcatcgtaac
    13321 aggaactcca gaagaagtag ctgccaacga agccagctat acaggatact atttgaaagg
    13381 aaagttacat catgaataaa cgcgtacaag catttctagc taaaatgcaa gaaaaagaac
    13441 tagatggtat catcatcaac aatcttaaaa acgtctatta tttgactggt ttttggggct
    13501 caaacggaac agtctttatc agccgtgacc gtcaggtctt agtgacagac tctcgctata
    13561 tcatcgcagc taagcaagaa accagtggtt ttgagattgt ggctgatcgt gatgaattgg
    13621 ctgtcattgc aggaattgtt aaggacatgg gcttgactcg tatcggtttt gaagatgaga
    13681 tttcagtatc ttattaccac cgtatgcagg cagcttttgc aggtttggac ttgcttccac
    13741 aaactcaatt tgtggaaggt attcgtatga ttaaggatga ggcagagatt gcagcgattc
    13801 gcaaggcttg ttctatctca gaccaagctt tccgcgatgc gcttgacttt atcaaaccag
    13861 gaaaaactga gattgaaatt gccaacttcc ttgatttccg catgcgtgag ttgggagcat
    13921 ctagcttatc ttttgatacg atcctagcta gcggtatcaa ttcttctaaa ccccatgccc
    13981 atccaatgca caaaccagtg gagttgggag aagccattac catggacttc ggctgtctct
    14041 atgaccacta tgtcagtgat atgacccgga ctatctatct agggcatgtt agcgatgagc
    14101 aggcagagat ttacaatacg gttctaaaag ctaaccaagc cttgattgac caagctaagg
    14161 caggcttagg tttccgtgac tttgacaaaa tccctcgtga tattatcatt gaggcaggtt
    14221 atggcgacta ctttactcac ggcattggcc acggtattgg tctggatatc catgaggaac
    14281 cctactttag ccagacttct acagaaacta ttaagacagg tatggccttg accgatgaac
    14341 caggtatcta tatcgaaggc aaatatggcg ttcgtatcga ggatgatatc ctgattacag
    14401 agacaggttg tgaattattg accctagctc caaaagagtt gatagtcatt tagttgtttg
    14461 tcaagaaaaa agtacgaaaa tgacgaaaaa agtcaaaaaa aattaaaaat aggtcgcaag
    14521 tcggatgttt tttatggtat aatagactaa actgatagta acatgtagcg aaaggggtag
    14581 gtacatgatt aaaatttata cagtctcaag ttgtactagc tgtaaaaaag caaaaacctg
    14641 gctcaatgcc caccagttaa gttataaaga acaaaacctt ggtaaagaag gaattacgag
    14701 agaagaatta ctggatattc taaccaaaac agataacgga atagccagca tcgtttcgtc
    14761 taaaaatcgc tatgccaaag cccttggagt ggatattgaa gatttgagtg tcaatgaagt
    14821 tctcaatctg attatggaaa caccgagaat tttaaagagc ccaatccttg tagatgaaaa
    14881 acgcctgcaa gttggctaca aggaagacga tattcgtgcc ttcctaccac gctctgtccg
    14941 taatgtagaa aatgcagaag cacgtttgcg tgcagctcta taaacatcaa ggctgggagc
    15001 acttcccagt cttattctat tttaatttca aaaagaaaga agaaagaaat gaaaaaaata
    15061 gttcttgtta gtctagcttt cctttttgtc ctggttggtt gcggacagaa aaaagaaact
    15121 ggaccagcta caaaaacaga aaaagatacg cttcagtcgg cattgccagt tattgaaaat
    15181 gctgagaaga atacagttgt aactaagact ttggtcttgc ccaagtcaga tgatggtagc
    15241 cagcaaactc aaaccattac atacaaggac aagacttttt tgagcttaac gattcaacaa
    15301 aaacgtccag tttctgatga gttgaagact tatatcgacc aacatggagt ggaagaaact
    15361 caaaaagctc ttcttgaagc ggaggagaag gataagtcta tcattgaagc tcgtaaattg
    15421 gcaggtttca aacttgaaac aaaactattg agcgcaacgg aacttcaaac aacgactagt
    15481 tttgattttc aagttctgga tgtcaagaag gcttcccagt tggaacatct gaagaatatt
    15541 ggttttgaaa atcttttgaa aaatgaacca agcaaatata tttcagatag attggcaaat
    15601 ggcgcgacag aacaatagaa aatccaaata aatagactgc ctgaattgta gaaggtaagg
    15661 aattatgcta taatggtact attctaagga aagagggtgt tagaatggga tttactgaag
    15721 aaacagtacg ttttaaattg gacgattcca ataaaaaaga aattagcgaa actttgacag
    15781 atgtttatgc ttcgttgaac gataagggtt acaacccaat taaccaaatc gtaggttacg
    15841 tattgagtgg agaccctgcc tacgttcctc gttataataa tgcacgaaat caaatccgta
    15901 agtatgagcg tgatgaaatc gttgaggaat tggttcgtta ctacctcaaa ggacaaggag
    15961 tcgatctata acctatgaga attatgggat tggacgtcgg ttcaaaaacg gtaggggtgg
    16021 cgattagcga tccgcttggt tttacagctc aagggcttga aatcatccag ataaatgaag
    16081 aacaaggcca atttggtttt gaccgcgtta aggaattggt tgatacttac aaggtggaac
    16141 gatttgtagt gggcttgcct aaaaacatga acaatacaag tggaccgcgc gtggaagcta
    16201 gtcaagcata cggagcaaag ctagaagagt tttttggttt accagtagac tatcaggatg
    16261 aacgcttgac aacagtggct gctgagcgca tgttgattga acaagcagat atcagtcgca
    16321 ataagcgcaa gaaagtcatt gataagttag cagctcagct gattttacaa aattatttag
    16381 atagaaaatt ttaatataaa ggagaggcta tgtcacacga tcataaccac gaccacgaag
    16441 aacgtgaact aatcacacta gtagatgagc aaggaaatga aaccttgttt gaaatccttt
    16501 tgacaattga tggaaaagaa gaatttggta aaaactatgt tcttctagta ccagttaacg
    16561 cagaagaaga cgaagacgga caagttgaaa tccaagctta ctcattcatc gaaaacgaag
    16621 atggaacaga aggcgaattg caaccaatcc cagaagactc agaagacgaa tggaacatga
    16681 ttgaagaagt cttcaacagc tttatggagg agtgatacag tctgggagac tgtatcagcc
    16741 caactcccag aaatggggaa gagttggaac gtccagtgga tgtttttagc ccatattcac
    16801 attcatagta gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt
    16861 gtttttatta gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt
    16921 gtatgtttga agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt
    16981 tgggtcgaat gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta
    17041 tccacgtaac agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta
    17101 tggggcatgg caaaaaagtt gcgaccttta cctcccctca tatcgtctct atcaatgacc
    17161 gaatctgcat taatgggcag cctatagcag acgcagactt tatccgtttg actgatcagg
    17221 tcaaggagat ggagaaaacg cttctgcaaa ctcctgccca gttgtccttt tttgaattgc
    17281 tgaccttggt tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag
    17341 tgggaattgg tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca
    17401 cctccattgg gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc
    17461 agaaagctgg tattttcaag gctggtaaga aggcagtgat tgcgaaattg cctccagaag
    17521 ctaggcttgc ctgtcagaaa aaagccgaat ctttagctgt taacctttat caggcaggtc
    17581 aagatttttt aatgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga
    17641 acataggctt agaaggagtc tatcagcagg agaatgcagc cttggcgttg caaacttttc
    17701 ttctttttat gagagaaaga aaggaagctg ttgatgaaca ggctgtaaga aaggccttgg
    17761 aacagaccca ttgggctggt cgcttggagc gtattcgccc acagatttat ttggatggtg
    17821 ctcataacct ccctgccttg actcgcttgg ctgagtttat caaagaaaaa gagcaggaag
    17881 gctatcgacc tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg
    17941 gttatttgac tgaaaaattg cctcaggtgg aactcaaggt gaccggcttt gactatcagg
    18001 gggctttgga cgaaagggat gtgacaggtt acgatatagt ttcttcttac cgagaattta
    18061 tcagcgattt tgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct
    18121 attttatctc agaagtacgg ggctacctgc tggaccgtga gcagataaat tgactccatt
    18181 ttttgaactt gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc
    18241 agaaaggaaa ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag
    18301 ttttagtctc ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca
    18361 gcaggtccaa cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa
    18421 tcaagcggct ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta
    18481 tactggtcag gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg
    18541 gactgagctc gaatctgacg gggatcagaa agtcaaacag gttacattgg attcagcaaa
    18601 tcaacgcatg attattggcg atgatgtcaa aatttacact gtaaacggta atcaaattgt
    18661 cgtagatgat atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc
    18721 aagtagaaag ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata
    18781 cttgccttct accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa
    18841 actatcaagg aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct
    18901 ttagtctttc gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag
    18961 gacgcatggc tcccatttta tggattactg tcctcattct actgagtatc atcacaatca
    19021 tttcgatagt caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct
    19081 ttgtgccagt atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa
    19141 aagaaatcaa acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc
    19201 tactaaaaga gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat
    19261 tgagtatgga taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg
    19321 gagaagctat gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct
    19381 tggaatatta cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc
    19441 aaaaggtagc tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta
    19501 ctttaacagg agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca
    19561 ataaagttat tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga
    19621 ttgttgatgg tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc
    19681 acgtcgagag atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa
    19741 aagccctgac acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt
    19801 ttgatcaata tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg
    19861 gaagtggacc caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa
    19921 tcaatcaagc aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt
    19981 taacagagac aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt
    20041 acataccaga taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt
    20101 ctgctggtgt tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg
    20161 tagacgaaga ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc
    20221 attatgaaaa tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt
    20281 ttcgaaatat atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt
    20341 atcaaaagct tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga
    20401 acttaggata caaaccagac ctatttttct tgtcttttac gaatagaaag aaagaggagg
    20461 ggaattcatg ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt
    20521 acaccgcttt cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc
    20581 atcgcaagct gacaatccta ggactttttg atatactaag acagataaat tgaacaggag
    20641 aaacgatatg agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct
    20701 agaataccaa atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa
    20761 aattttacta tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga
    20821 cttaatgagt gcacaagaag tgcaggattt ttatgcaggt tgggcgcttc atcagacagg
    20881 gaagatttac agcaactatt atggaagtca aggtttgctt tattatttgc tgacttacgt
    20941 gagtcagggc ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt
    21001 tttccttttt agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt
    21061 gactattttt tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt
    21121 agcgcttcct ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag
    21181 ccatgataag ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc
    21241 cttatcatcg ctcctgttta ttgctgtagt gagtttaggc ttgttggtct ttaaccttgg
    21301 gcatagacgc tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact
    21361 tgtcttttat ccaactgcct actatagtgc tgcaacagga agttttgggg atgcgattag
    21421 tggtattcgt tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa
    21481 tatgtttttt tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg
    21541 tctctttcaa tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgtggt
    21601 aattttaggt ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat
    21661 ggtcgtcttc cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg
    21721 gcgtagtgct agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa
    21781 aggaaatcta tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat
    21841 gaagtttgtc ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa
    21901 agaggagaca aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg
    21961 taagagtgag cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga
    22021 ggaaaatcgt aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt
    22081 aaatgacaag gtggaagtct ggtctgaagt ggaaacactc ttaaaagaaa attaccaaca
    22141 agtaaagact gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct
    22201 tgtgtatttt taaaaatttt aagattttta acacaagata ttgatttttc tttttagagt
    22261 ggtataatac tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa
    22321 gaaaaaatta caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta
    22381 tttgatgtgg acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg
    22441 acacccctgg ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat
    22501 agtcgctttc cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc
    22561 cttgaagcca aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat
    22621 tttgagcgct caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac
    22681 cagacagttg tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat
    22741 ttgacagcag ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc
    22801 aatgcccacc aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct
    22861 atgaccaact gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga
    22921 aatgcagagg tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc
    22981 attgccaacg ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt
    23041 ttggcgcctt atgcagagaa gaactatcaa aaacatctca aagatgcaga agagtgggta
    23101 ttgcctgaaa aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc
    23161 atgcaatctc ttgagtatga aatcaatact ctctttactt caaatggaca aacacctttt
    23221 acttcgctag gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt
    23281 ttaaacattc gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt
    23341 attttcactc tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag
    23401 cagttggctc ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag
    23461 attgttgact tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga
    23521 tggaaggatg aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg
    23581 gttaatctgc ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc
    23641 ttcaacgagc gaatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa
    23701 gaggcgacac cagcgaatgc tcctatcctt tatcagtacg gtgcttttgg ccatcgtcta
    23761 ggtaaagaag aaagtgttga ccagctcttt aagaatcgtc gtgcgaccgt ttcgctgggc
    23821 tatatcggct tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca
    23881 gatgctaagg aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg
    23941 tcaaaccaat atggctacca tttctctatc tactcaacac catccgaaag tctgacagac
    24001 cgtttctgcc gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa
    24061 tactacacca actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg
    24121 gactttgaga aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag
    24181 tatccagtcc ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac
    24241 cgtgtaggct atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa
    24301 ggggattttg aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct
    24361 aaaacagtag atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg
    24421 atggtcaacg ggcgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg
    24481 attaaaatag ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac
    24541 tagacgataa ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag
    24601 ctggtaagaa agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa
    24661 aataaaagtg agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc
    24721 agaccaagat tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt
    24781 cagtcgcctc acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta
    24841 gaaagcaatc aggaacagga aatggggatt aatctgcctg aaggatgggt tcctgcaatt
    24901 cagttagtgg ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc
    24961 ctcagtaact ttctactaga agaaggtggc cacattggct actccattcg tccatctgaa
    25021 agaggcaagg gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag
    25081 aacatcaaga aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagccatt
    25141 ctagcaaatg gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag
    25201 gtagcgaatg aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg
    25261 tatcattgac tacaaggcct ttaactttgt ggacggcgaa ggcgtgcgca actctctcta
    25321 tgtatcaggc tgtatgtttc actgcgaggg atgttataat gttgcgactt ggtcttttaa
    25381 tgctggcatt ccctatacag cagaattaga agagcagatt atggcagacc ttgcccaacc
    25441 ctatgttcaa ggcttgactt tgctgggagg ggagcctttt ctcaatactg gcattctctt
    25501 gcctctagtt aaacgcatcc gaaaggaatt gccagacaag gacatttggt cctggacggg
    25561 ctacacttgg gaagaaatga tgttggaaac tccagataaa ctggaactct tgtcactgat
    25621 tgacattctt gtcgatggac gatacgatcg aactaagaga aatctcatgc tccagtttcg
    25681 aggttcgtcc aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt
    25741 gatttgggac aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag
    25801 aaaaaggact tagtagacca actagtctca gagatcgaga cggggaaagt caggacactg
    25861 ggaatatacg gtcatggagc ttcaggtaaa tcaacctttg cacaggaatt gtaccaagct
    25921 ttagattcta ctacagtaaa tttgctagag acagatcctt atatcacctc aggacgccat
    25981 ctggtagtac ccaaggacgc gccgaatcaa aaggtgacag ccagtctgcc agtggcgcat
    26041 gaactggaga gtttgcagag agatatcctt gccttgcagg cgggtatgga tgtcttgaca
    26101 attgaagaac cttggaaggc tagtgaggtc ttgtctggag ccaaaccaat tttgattgtc
    26161 gaagggatgt ctgttggctt tctacccaag gaactctttg aaaaaccatc tgtttctaca
    26221 cggatgagga gaccgaatta aagcgacgcc ttgctagaga tacgactgtg agaaatcgcg
    26281 atgcatcctt tatattggct agccatcaga tgagacggga gcagtatctg cgatactata
    26341 aagaaactga gtctaaggcg gatatcttag tggaccaatc agaagataaa tttgatgtca
    26401 agaggactta actatagaag aaatatagaa gaaaatccct aattttagaa agaaaaagta
    26461 ggaaaacagt ttcatcccaa aaaaacgaaa aaacctaaca aatcccttgc aatcgcaggg
    26521 gctttgtgtt attctattat ggtgctgtaa attacagcct tagttttgat gcaagaggtt
    26581 gcgacacgct cggttgcatt gccacgcaac accgcgtcgg ttttcttgtg gagctagcct
    26641 attatcttaa atagacgaaa aggagaaaaa gatggcaaac aaaaaaatcc gtatccgttt
    26701 gaaagcttac gaacaccgta cgcttgacac agcggctgca aaaatcgtag aatcagctac
    26761 tcgtacaggt gcacaagttg cgggtccaat cccacttcca actgaacgta gcctctacac
    26821 aatcattcgt gcgactcaca aatacaaaga ctctcgcgaa caatttgaaa tgcgtacaca
    26881 caaacgtttg atcgatatcg ttaacccaac tcaaaaaaca gttgatgcct tgatgaaatt
    26941 ggatcttcca agtggtgtaa acgtagaaat caaactttaa tctaaaatat aaaagagcag
    27001 aggctggtgt ttcaatctaa ttgaacacgg gctaaactcg gtgtgaaaaa gataaacttc
    27061 ctcgcgtctg ctagacactg tgtcagtttc ctattttcac gttgagtttg acgccctttg
    27121 tatcttagac ttgagcataa aaaacgctcg ttaaaaactt tttgaataaa aatatagaaa
    27181 aggaactatt ttctcatgac aaaaggaatc ttagggaaaa aagtgggaat gactcaaatc
    27241 ttcactgaag ctggcgaatt gatccctgta acagttattg aagcaactcc aaacgttgtt
    27301 cttcaagtta aaactgttga aacagacgga tacaacgcta tccaagttgg tttcgatgac
    27361 aaacgcgaag tattgagcaa caaacctgct aaaggacatg tagcgaaagc taacacggct
    27421 cctaagcgct tcattcgtga attcaaaaac gttgaaggct tggaagttgg tgctgaaatt
    27481 acagttgaaa cattcgcagc tggagacgtt gttgacgtaa ctggtacttc taaaggtaaa
    27541 ggtttccaag gtgttatcaa acgccacgga caatcacgtg gaccaatggc tcacggttct
    27601 cgttaccacc gtcgtccagg ttctatggga cctgttgcac ctaaccgcgt attcaaaggt
    27661 aaaaaccttg caggacgtat gggtggtgac cgcgtaacaa ttcaaaatct tgaagttgta
    27721 caagttgttc cagaaaagaa cgttatcctt atcaaaggta acgtaccagg tgctaagaaa
    27781 tctcttatca ctatcaaatc agcagttaaa gctggtaaat aataaagaaa ggggaaatca
    27841 gtcacaatgg caaacgtaac attatttgac caaactggta aagaagctgg ccaagttgtt
    27901 cttagcgatg cagtatttgg tatcgaacca aatgaatcag ttgtgtttga tgtaatcatc
    27961 agccaacgcg caagccttcg tcaaggaaca cacgctgtta aaaaccgctc tgcagtatca
    28021 ggtggtggac gcaaaccatg gcgtcaaaaa ggaactggac gtgctcgtca aggttctatc
    28081 cgctcaccac aatggcgtgg tggtggtgtt gtcttcggac caactccacg ttcatacggc
    28141 tacaaacttc cacaaaaagt tcgtcgccta gctcttaaat cagtttactc tgaaaaagtt
    28201 gctgaaaaca aattcgtagc tgtagacgct ctttcattta cagctccaaa aactgctgaa
    28261 tttgcaaaag ttcttgcagc attgagcatc gattctaaag ttcttgttat ccttgaagaa
    28321 ggaaatgaat tcgcagctct ttcagctcgt aaccttccaa acgtgaaagt tgcaactgct
    28381 acaactgcaa gtgttcttga catcgcaaat agcgacaaac ttcttgtcac acaagcagct
    28441 atctctaaaa tcgaggaggt tcttgcataa tgaatttgta tgatgttatc aaaaaacctg
    28501 tcatcactga aagctcaatg gctcaacttg aagcagggaa atatgtattt gaagttgaca
    28561 ctcgtgcaca caaacttttg atcaagcaag ctgttgaagc tgctttcgaa ggtgttaaag
    28621 ttgccaatgt taacacaatc aacgtaaaac caaaagctaa acgtgttgga cgttacactg
    28681 gttttactaa caaaactaaa aaagctatca tcacacttac agctgattct aaagcaatcg
    28741 agttgtttgc tgctgaagct gaataatcta aggaggaaat atcgtgggaa ttcgtgttta
    28801 taaaccaaca acaaacggtc gccgtaatat gacttctttg gatttcgctg aaatcacaac
    28861 aagcactcct gaaaaatcat tgcttgttgc attgaagagc aaggctggtc gtaacaacaa
    28921 cggtcgtatc acagttcgtc accaaggtgg tggacacaaa cgtttctacc gtttggttga
    28981 cttcaaacgt aataaagaca acgttgaagc agttgttaaa acaatcgagt acgatccaaa
    29041 ccgttctgca aacatcgctc ttgtacacta cactgacggt gtgaaagcat acatcatcgc
    29101 tccaaaaggt cttgaagtag gtcaacgtat cgtttcaggt ccagaagcag atatcaaagt
    29161 cggaaacgct cttccacttg ctaacatccc agttggtact ttgattcaca acatcgagtt
    29221 gaaaccaggt cgtggtggtg aattggtacg tgctgctggt gcatctgctc aagtattggg
    29281 ttctgaaggt aaatacgttc ttgttcgtct tcaatcaggt gaagttcgta tgattcttgg
    29341 aacttgccgt gctacagttg gtgttgtcgg aaacgaacaa catggacttg taaaccttgg
    29401 taaagcagga cgtagccgtt ggaaaggtat ccgcccaaca gttcgtggtt ctgtaatgaa
    29461 ccctaacgat cacccacacg gtggtggtga aggtaaggca ccagttggtc gtaaagcacc
    29521 atctactcca tggggcaaac ctgctcttgg tcttaaaact cgtaacaaga aagcgaaatc
    29581 tgacaaactt atcgttcgtc gtcgcaacga gaaataatat taaactagtc gcttaagcaa
    29641 ctagtaaatc cgccagctcg gtagcgctcc ataggagtgc aagccgctgt ggtacaacat
    29701 ttaaaggaga aaatataaaa atgggacgca gtcttaaaaa aggacctttc gtcgatgagc
    29761 atttgatgaa aaaagttgaa gctcaagcta acgacgaaaa gaaaaaagtt attaaaactt
    29821 ggtcacgtcg atcaacgatc ttcccaagtt tcattggtta cactattgca gtttatgacg
    29881 gacgtaaaca cgtacctgtt tacatccaag aagacatggt aggccacaaa cttggtgaat
    29941 ttgcaccaac tcgtacttac aaaggtcacg ctgcagacga caagaaaaca cgtagaaaat
    30001 aaggagaaca taaatggcag aaattacttc agctaaagca atggctcgta cagtacgtgt
    30061 ttcacctcgt aaatcacgtc ttgttcttga taacatccgt ggtaaaagcg tagccgatgc
    30121 aatcgcaatc ttgacattca ctccaaacaa agctgctgaa atcatcttga aagttttgaa
    30181 ctcagctgta gctaacgctg aaaacaactt tggtttggat aaagctaact tggtagtatc
    30241 tgaagcattc gcaaacgaag gaccaactat gaaacgtttc cgtccacgtg cgaaaggttc
    30301 agcttcacca atcaacaaac gtacagctca catcactgta gctgttgcag aaaaataagg
    30361 aggtaaaatc gtgggtcaaa aagtacatcc aattggtatg cgtgtcggca tcatccgtga
    30421 ttgggatgcc aaatggtatg ctgaaaaaga atacgcggat taccttcatg aagatcttgc
    30481 aatccgtaaa ttcgttcaaa aagaacttgc tgacgcagca gtttcaacta ttgaaatcga
    30541 acgcgcagta aacaaagtta acgtttcact tcacactgct aaaccaggta tggttatcgg
    30601 taaaggtggt gctaacgttg atgcactccg tgcaaaactt aacaaattga ctggaaaaca
    30661 agtacacatc aacatcatcg aaatcaaaca acctgatttg gatgctcacc ttgtaggtga
    30721 aggaattgct cgtcaattgg agcaacgtgt tgctttccgt cgtgcacaaa aacaagcaat
    30781 ccaacgtgca atgcgtgctg gagctaaagg aatcaaaact caagtatcag gtcgtttgaa
    30841 cggtgcagat atcgcccgtg ctgaaggata ctctgaagga actgttccgc ttcacacact
    30901 tcgtgcagat atcgattacg cttgggaaga agcagatact acatacggta aacttggtgt
    30961 taaagtatgg atctaccgtg gtgaagttct tccagctcgt aaaaacacta aaggaggtaa
    31021 ataaccaatg ttagtaccta aacgtgttaa acaccgtcgt gagttccgtg gaaaaatgcg
    31081 cggtgaagca aaaggtggaa aagaagtagc attcggtgaa tacggtcttc aagctacaac
    31141 tagccactgg atcactaacc gccaaatcga agctgctcgt atcgccatga ctcgttacat
    31201 gaaacgtggt ggtaaagttt ggattaaaat cttcccacac aaatcataca ctgctaaagc
    31261 tatcggtgtg cgtatgggat ctggtaaagg ggcacctgaa ggttgggtag caccagttaa
    31321 acgtggtaaa gtgatgttcg aaatcgctgg tgtatctgaa gagattgcac gtgaagcgct
    31381 tcgacttgct agccacaaat tgccagttaa atgtaaattc gtaaaacgtg aagcagaata
    31441 aggagaaggc atgaaactta atgaagtaaa agaatttgtt aaagaacttc gtggtctttc
    31501 tcaagaagaa ctcgcgaagc gcgaaaacga attgaaaaaa gaattgtttg aacttcgttt
    31561 ccaagctgct actggtcaat tggaacaaac agctcgcttg aaagaagtta aaaaacaaat
    31621 cgctcgtatc aaaacagttc aatctgaagc gaaataatag actagggaag gagaaatttc
    31681 aatggaacgc aataatcgta aagttcttgt tggacgtgtt gtatctgaca aaatggacaa
    31741 gacaatcaca gttgtagttg aaacaaaacg taaccaccca gtctatggta aacgtattaa
    31801 ctactctaaa aaatacaaag ctcatgatga aaacaatgtt gccaaagaag gcgatatcgt
    31861 acgtatcatg gaaactcgcc cgctttcagc tacaaaacgt ttccgtcttg tagaagttgt
    31921 tgaagaagcg gtcatcatct aatcaaacct gaaaggagaa aactgaaatg attcaaacag
    31981 aaactcgttt gaaagtcgca gacaacagcg gtgctcgcga aatcttgact atcaaagttc
    32041 ttggtggttc aggacgtaaa tttgcaaaca tcggtgatgt tatcgtggca tctgtaaaac
    32101 aagctactcc tggtggtgcg gttaaaaaag gtgacgttgt taaagcagtt atcgttcgta
    32161 ctaaatcagg tgctcgtcgt gctgatggtt catacatcaa atttgacgaa aacgcagcag
    32221 ttatcatccg tgaagacaaa actcctcgcg gaacacgtat ctttggccca gttgcacgtg
    32281 aattgcgtga aggtggcttc atgaagatcg tgtcacttgc tccagaagta ctttaatttt
    32341 taggaacaaa ctagtcccct agcttcaagc tagggtgccc ttatgggcgt aagaaaaatc
    32401 aaggagaaac ctaatgtttg taaaaaaagg cgacaaagtt cgcgtaatcg ctggtaaaga
    32461 taagggaaca gaagctgttg tccttactgc ccttccaaaa gtaaacaaag ttatcgttga
    32521 aggtgttaac attgttaaga aacaccaacg tccaactaac gagcttcctc aaggtggtat
    32581 catcgagaaa gaagcagcta tccacgtatc aaacgttcaa gttttggaca aaaatggtgt
    32641 agctggtcgt gttggttaca aatttgtaga cggtaaaaaa gttcgctaca acaaaaaatc
    32701 aggcgaagtg cttgattaat cacgaaggaa aggagaagta taatggcaaa tcgtttaaaa
    32761 gaaaaatatc ttaatgaagt agttcctgct ttgacagaac aattcaacta ctcatcagtg
    32821 atggctgtgc ctaaagtaga taagattgtt ttgaacatgg gtgttggtga agctgtatca
    32881 aacgctaaaa gccttgaaaa agctgctgaa gaattggcac ttatctcagg tcaaaaacca
    32941 cttatcacta aagctaaaaa atcaatcgcc ggcttccgtc ttcgtgaagg tgttgcgatc
    33001 ggtgcaaaag ttacccttcg tggtgaacgt atgtacgaat tcttggataa attggtatca
    33061 gtttcacttc cacgtgtacg tgacttccac ggtgttccaa caaaatcatt tgatggacgc
    33121 gggaactaca cacttggtgt gaaagaacaa ttaatcttcc cagaaatcaa cttcgatgac
    33181 gttgacaaaa ctcgtggtct tgacatcgtt atcgtaacaa ctgctaacac tgacgaagag
    33241 tcacgtgcat tgcttacagg ccttggaatg ccttttgcaa aataatatag gaggtaaatc
    33301 taatggctaa aaaatcaatg gtagctagag aggctaaacg ccaaaaaatt gttgaccgtt
    33361 atgctgaaaa acgtgctgca ttaaaggcgg caggggacta cgaaggttta tctaaattac
    33421 ctcgcaacgc ctcaccgact cgtttacata atcgttgtag agttacgggg cgcccacatt
    33481 cagtttaccg caaatttggt ctgagtcgta tcgcttttcg cgaacttgcg cataaaggtc
    33541 aaattcctgg tgtaacaaaa gcatcttggt aatttaagat atcaagagcg tcaaaactcc
    33601 aagtaaaaat aggaaacttg acgaagaaac taaagtttct aggaaagttt atctttttca
    33661 cacagagttt agcccgggtt caattgggct tgccaatttg aacacgagct acagctttgg
    33721 caaaaaagac caatttgctt tggagcattg cttctgcatt aaattgtcta tttttgctcg
    33781 tgctgttacg ctctttgtat catgtattaa ctagcaagtg caacttgcaa actactagta
    33841 agaggagaaa aacaaaatgg ttatgactga cccaatcgca gacttcctaa ctcgtattcg
    33901 taatgctaac caagctaaac acgaagtact tgaagtacct gcatcaaaca tcaaaaaagg
    33961 gattgctgaa atccttaaac gcgaaggttt tgtaaaaaac gttgaaatca ttgaagatga
    34021 caaacaaggc gtcatccgtg tatttcttaa atacggacca aatggtgaga aagttatcac
    34081 taacttgaaa cgtgtttcta aaccaggact tcgtgtctac aaaaaacgtg aagaccttcc
    34141 aaaagttctt aacggacttg gaattgccat cctttcaact tctgaaggtt tgcttactga
    34201 taaagaagca cgccaaaaga atgttggtgg tgaggttatc gcttacgttt ggtaaaatca
    34261 agatacaaag ctcgtaaaga acaaagcaaa attaggaagt tggagaagtt tgtttacaaa
    34321 caagccaact tatctatttt gcacagttct tagagcgtgt tcagttcagc tcttgaacta
    34381 aataagtatc tgaaccccgt gaaaactggc cgttctggcc tgacaatcta acaggagaaa
    34441 ataaacatgt cacgtattgg taataaagtt atcgtgttgc ctgctggtgt tgaactcgct
    34501 aacaatgaca acgttgtaac tgtaaaagga cctaaaggag aacttactcg tgagttctca
    34561 aaagatattg aaatccgtgt ggaaggtact gaaataactc ttcaccgtcc aaacgattca
    34621 aaagaaatga aaactatcca cggaactact cgtgcccttt tgaacaacat ggttgttggt
    34681 gtatcagaag gattcaagaa agaacttgaa atgcgtgggg ttggttaccg tgcacagctt
    34741 caaggatcta aacttgtttt ggctgttggt aaatctcatc cagacgaagt tgaagctcca
    34801 gaaggaatta cttttgaact tccaaaccca acaacaatcg ttgttagcgg aatttcaaaa
    34861 gaagtagttg gtcaaacagc tgcttacgta cgtagccttc gttcaccaga accatataaa
    34921 ggtaaaggta tccgttacgt tggtgaattc gttcgccgta aagaaggtaa aacaggtaaa
    34981 taatgttgag tggttgatca tcaaccacca acctattttc caactttgtg catagcacac
    35041 gatttaaaac taaagaggtg aaaactgtga tttcaaaacc agataaaaac aaactccgcc
    35101 aaaaacgcca ccgtcgcgtt cgcggaaaac tctctggaac tgctgatcgc ccacgtttga
    35161 acgtattccg ttctaataca ggcatctacg ctcaagtgat tgatgacgta gcgggtgtaa
    35221 cgctcgcaag tgcttcaact cttgataaag aagtttcaaa aggaactaaa actgaacaag
    35281 ccgttgctgt cggtaaactc gttgcagaac gtgcaaacgc taaaggtatt tcagaagtgg
    35341 tgttcgaccg cggtggatat ctatatcacg gacgtgtgaa agctttggct gatgcagctc
    35401 gtgaaaacgg attgaaattc taataggagg acactagaaa atggcattta aagacaatgc
    35461 agttgaatta gaagaacgcg tagttgctgt caaccgtgtt acaaaagttg ttaaaggtgg
    35521 acgtcgtctt cgtttcgcag ctcttgttgt tgttggtgac cacaatggtc gcgtaggatt
    35581 tggtactggt aaagctcaag aagttccaga agcaatccgt aaagcagtag atgatgctaa
    35641 gaaaaacttg atcgaagttc ctatggttgg aacaacaatc ccacacgaag ttctttcaga
    35701 attcggtgga gctaaagtat tgttgaaacc tgctgtagaa ggttctggag ttgccgctgg
    35761 tggtgcagtt cgtgccgttg tggaattggc aggtgtggca gatattacat ctaaatcact
    35821 tggttctaac actccaatca acattgttcg tgcaactgtt gaaggtttga aacaattgaa
    35881 acgcgctgaa gaaattgctg cccttcgtgg tatttcagtt tctgatttgg cataagaaag
    35941 gggataaaat ggctcaaatt aaaattactt tgactaagtc tccaatcgga cgcattccat
    36001 cacaacgtaa aactgttgta gcacttggac ttggcaaatt gaacagctct gttattaaag
    36061 aagataacgc tgctatccgt ggtatgatta cagcagtatc tcacttagta acagttgaag
    36121 aagtaaacta atgaagtttt aggggatgtg cactgtacca tcccctaaaa ctagatatag
    36181 tcatctatga tgacatcgta taggcgagtt gatgggggag acaacctttt ctcccttatc
    36241 ggcgctagca ttttacaaaa gaggagaaaa taaaaatgaa acttcatgaa ttgaaacctg
    36301 cagaaggttc tcgtaaagta cgtaaccgcg ttggtcgtgg tacttcatca ggtaacggta
    36361 aaacatctgg tcgtggtcaa aaaggtcaaa aagctcgtag cggtggcgga gttcgccttg
    36421 gttttgaagg tggacaaact ccattgttcc gtcgtcttcc aaaacgtgga ttcactaaca
    36481 tcaacgctaa agaatacgca attgtgaacc ttgaccaatt gaacgtcttt gaagatggtg
    36541 ctgaagtaac tccagttgtt cttatcgaag caggaattgt taaagctgaa aagtcaggta
    36601 ttaaaattct tggtaacggt gagttgacta agaaattgac tgtgaaagca gctaaattct
    36661 ctaaatcagc tgaagaagct atcactgcta aaggtggttc agtagaagtc atctaagaga
    36721 ggtgacctat gttttttaaa ttattaagag aagctcttaa agtcaagcag gttcgatcaa
    36781 aaattttatt tacaattttt atcgttttgg tctttcgtat cggaactagc attacagttc
    36841 ctggtgtgaa tgccaatagc ttgaatgctt taagtggatt atccttctta aacatgttga
    36901 gcttggtgtc ggggaatgcc ctaaaaaact tttcgatttt tgccctagga gttagtccct
    36961 atatcaccgc ttctattgtt gtccaactct tgcaaatgga tattttaccc aagtttgtag
    37021 agtggggtaa acaaggggaa gtaggtcgaa gaaaattgaa tcaagctact cgttatattg
    37081 ctctagttct cgcttttgtg caatctatcg ggattacagc tggttttaat accttggctg
    37141 gagctcaatt gattaaaact gctttaactc cacaagtttt tctgacgatt ggtatcatct
    37201 taacagctgg tagtatgatt gtcacttggt tgggtgagca aattacagat aagggatacg
    37261 gaaacggtgt ttccatgatt atctttgccg ggattgtttc ctcaattcca gagatgattc
    37321 agggcatcta tgtggactac tttgtgaacg tcccaagtag ccgtatcact tcatctatca
    37381 ttttcgtaat cattttgatt attactgtat tgttgattat ttactttaca acttatgttc
    37441 aacaagcaga atacaaaatt ccaatccaat atactaaggt tgcacaaggt gctccatcta
    37501 gctcttacct tccgttaaag gtaaaccctg ctggagttat ccctgttatc tttgccagtt
    37561 cgattactgc agcgcctgcg gctattcttc agtttttgag tgccacaggt catgattggg
    37621 cttgggtaag ggtagcacaa gagatgttgg caactacttc tccaactggt attgccatgt
    37681 atgctttgtt gattattctc tttacattct tctatacgtt tgtacagatt aatcctgaaa
    37741 aagcagcaga gagcctacaa aagagtggtg cctatatcca tggagttcgt cctggtaaag
    37801 gtacagaaga atatatgtct aaacttcttc gtcgtcttgc aactgttggt tccctcttcc
    37861 ttggtgtgat ttccatttta ccgattgcag ctaaagatgt atttggtctt tctgatgttg
    37921 ttgcctttgg tggaacaagt ctcttgatca ttatctctac aggtatcgaa ggaatcaagc
    37981 aattggaagg ttacctattg aaacgtaagt atgttggttt catggacaga acagaataaa
    38041 agtatttact gaatcagtaa atgctgaggg agtggaggtt taaactctga catttgtaag
    38101 agttggatct cccctcttct attttgtttt taaatagggg tgaaaagact ttttgcttct
    38161 atttaaaaat aaaataagga gatcaaatca tgaatctttt gattatgggc ttacctggtg
    38221 caggtaaggg aactcaagca gcaaaaatcg tagaacaatt ccatgttgca catatctcaa
    38281 caggtgatat gttccgcgct gcaatggcaa atcaaactga aatgggtgtt cttgctaagt
    38341 catatattga caagggtgaa ttggttcctg acgaagttac aaatggaatc gtaaaagaac
    38401 gcctttcaca agatgatatt aaagaaacag gattcttatt ggatggttac ccacgtacaa
    38461 ttgaacaagc tcatgccttg gacaaaacat tggctgaact tggcattgaa ctagaaggta
    38521 ttatcaatat tgaagtgaac cctgacagcc tcttggaacg tttgagtggc cgtatcatcc
    38581 accgcgtaac tggagaaact ttccacaagg tctttaaccc accagttgac tataaagaag
    38641 aagattacta ccaacgtgaa gatgataagc ctgagacagt aaaacgtcgt ttggatgtta
    38701 atattgctca aggagaacca atcattgctc actaccgtgc caaaggtttg gttcatgaca
    38761 tcgaaggtaa tcaagatatc aatgatgtct tctcagatat tgaaaaagta ttgacaaatt
    38821 tgaaataaag cgtttttcgc acttgcaaaa atccgctaca aatgttatac tgagatagtc
    38881 tgacttataa ttgttgtctc tgtgtctaga ggcatcgaat cgaaatttat ggaggtgctt
    38941 ttgcgtggca aaagacgatg tgattgaagt tgaaggcaaa gtagttgata caatgccgaa
    39001 tgcaatgttt acggttgaac ttgaaaatgg acatcagatt ttagcaacag tttctggtaa
    39061 aattcgtaaa aactatattc gtattttagc gggagatcgt gttactgtcg aaatgagtcc
    39121 atatgacttg acacgtggac gtatcactta ccgctttaaa taatcgaaaa acttggaggg
    39181 ataagaaatg aaagtaagac catcggtcaa accaatttgc gaatactgta aagttattcg
    39241 tcgtaatggt cgtgttatgg taatttgccc agcaaatcca aaacacaaac aacgtcaagg
    39301 ataagataga aaggagaaaa catggctcgt attgctggag ttgatattcc aaatgacaaa
    39361 cgcgtagtaa tctcattgac ttatgtttat ggtatcggac ttgcaacatc taagaaaatt
    39421 ttggctgctg ctggaatctc agaagatgtt cgtgtacgtg atcttacatc agatcaagaa
    39481 gatgctatcc gtcgtgaagt ggatgcaatc aaagttgaag gtgaccttcg tcgtgaagta
    39541 aacttgaaca tcaaacgttt gatggaaatc ggttcatacc gtggtatccg tcaccgtcgt
    39601 ggacttcctg tccgtggaca aaatactaaa aacaacgctc gcactcgtaa aggtaaagct
    39661 gttgcgattg ctggtaagaa aaaataatat aggaggtaaa agtcttggct aaaccaacac
    39721 gtaaacgtcg tgtgaaaaag aatatcgaat ctggtattgc tcatattcac gctacattta
    39781 ataacactat tgttatgatt actgatgtgc atggtaatgc aattgcttgg tcatcagctg
    39841 gtgctcttgg tttcaaaggt tctcgtaaat ctacaccatt cgctgctcaa atggcttctg
    39901 aagctgctgc taaatctgca caagaacacg gtcttaaatc agttgaagtt actgtaaaag
    39961 gtccaggttc tggtcgtgag tcagctattc gtgcgcttgc tgccgctggt cttgaagtaa
    40021 cagcaattcg tgatgtgact ccagtgccac acaatggtgc tcgtcctcca aaacgtcgcc
    40081 gtgtataatc atcgcattac actgcttttc gtttaagagg gagtaactaa atgatcgagt
    40141 ttgaaaaacc aaatataaca aaaattgatg aaaataaaga ttatggcaag tttgtaatcg
    40201 aaccacttga acgtggctac ggtacaactc ttggtaactc tcttcgtcgt gtacttctag
    40261 cttctctacc aggagcagct gtgacatcta tcaacattga tggtgtgtta catgagtttg
    40321 acacagttcc aggtgttcgt gaagacgtga tgcaaatcat tctgaacatt aaaggaattg
    40381 cagtgaaatc gtacgttgaa gacgaaaaaa tcatcgaact ggatgttgaa ggtcctgctg
    40441 aagtaacagc tggtgacatt ttgacagata gcgatattga aattgtaaat ccagatcatt
    40501 atctctttac aatcggtgaa ggttcttctc taaaagcgac tatgactgtt aacagtggtc
    40561 gtggatatgt acctgctgat gaaaataaaa aggataatgc accagttgga acacttgctg
    40621 tagattctat ttatacacca gttacaaaag tcaactatca agtggaacct gctcgtgtag
    40681 gtagcaatga tggtttcgac aaattaaccc ttgaaatctt gacaaatgga acaattattc
    40741 cagaagatgc tttagggctt tcagcacgta ttttgacaga acatcttgat ttgtttacaa
    40801 atcttactga gattgctaag tcaactgaag tgatgaaaga agctgatact gaatctgacg
    40861 accgtatttt agatcgtacg attgaggaac tggacttgtc tgtgcgttca tacaactgtt
    40921 taaaacgtgc cggtatcaat actgtgcatg atttgacaga aaaatctgaa gcagagatga
    40981 tgaaagtacg aaatcttgga cgcaagagtt tggaagaagt gaaactcaaa ctcattgatt
    41041 tgggtcttgg attaaaagat aaataaagga ggaatacatg gcttaccgta aactaggacg
    41101 cactagctca caacgtaaag caatgcttcg cgatttgaca actgaccttt tgatcaacga
    41161 atcaatcgtg acaactgaag ctcgtgctaa agaaatccgt aaaactgttg aaaaaatgat
    41221 tactctaggt aaacgtggtg atttgcatgc acgtcgtcaa gcagctgctt tcgtacgtaa
    41281 tgaaatcgca tctgaaaact atgatgaagc aactgataag tacacttcta ctacagcact
    41341 tcaaaaattg ttctcagaaa tcgcacctcg ttatgctgaa cgtaacggtg gatacactcg
    41401 tatccttaaa actgaaccac gtcgtggtga tgcagcgcca atggcgatca tcgaattagt
    41461 ataaaatcat caattttgtt gagtgttatg atgatggagt cttgtgctct tagtctagct
    41521 ctggtctacc gctaggattt cggtcctagc gggaacactc atcataagtt gggatagtag
    41581 acgcttgttt acgaaattgt ttttttctta agaacaactt cgtaagcagg cgtttttgag
    41641 tattttcgtt agaattatgc tatactattt gaaaagaatc ctgtttaatg ttaaggtttc
    41701 ttattttaag aagaattgga gtttacttat gaaagccatt ataactgttg ttggtaaaga
    41761 taaatctgga attgttgcag gtgtttctgg taaaattgca gaattaggat tgaatattga
    41821 cgatatctct caaactgtct tggatgaata ttttacgatg atggctgttg tatctagtga
    41881 tgaaaagcaa gattttacct atcttcgtaa tgaatttgaa gcttttgggc aaactttgaa
    41941 tgtaaaaatc aatattcaga gtgcagcgat tttcgaagct atgtataata tctaggaggt
    42001 catcatggat attagacaag ttactgaaac catcgccatg attgaggagc aaaacttcga
    42061 tattagaacc attaccatgg ggatttctct tttggactgt atcgatccag atatcaatcg
    42121 tgctgcggag aaaatctatc aaaaaattac gacaaaggcg gctaatttag tagctgttgg
    42181 tgatgaaatt gcggctgagt tgggaattcc tatcgttaat aagcgtgtat cggtgacacc
    42241 tatttctctg attggggcag cgacagatgc gacggactac gtggttctgg caaaagcgct
    42301 tgataaggct gcgaaagaga ttggtgtgga ctttattggt ggtttttctg ccttagtaca
    42361 aaaaggttat caaaagggag atgagattct catcaattcc attcctcgcg ctttggctga
    42421 gacggataag gtctgctcgt cagtcaatat cggctcaacc aagtctggta ttaatatgac
    42481 ggctgtggca gatatgggac gaattatcaa ggaaacagca aatctttcag atatgggagt
    42541 ggccaagttg gttgtattcg ctaatgctgt tgaggacaat ccatttatgg cgggtgcctt
    42601 tcatggtgtt ggggaagcag atgttatcat caatgtcgga gtttctggtc ctggtgtggt
    42661 gaaacgtgct ttggaaaaag ttcgtggaca gagctttgat gtagtagccg aaacagttaa
    42721 gaaaactgcc tttaaaatca ctcgtatcgg tcaattggtt ggtcaaatgg ccagtgagag
    42781 actgggtgtg gagtttggta ttgtggactt gagtttggca ccaacccctg cggttggaga
    42841 ctctgtggca cgtgtccttg aggaaatggg gctagaaaca gttggcacgc atggaacgac
    42901 ggctgccttg gccctcttga acgaccaagt taaaaagggt ggagtgatgg cctgcaacca
    42961 agtcggtggt ttatctggcg cctttatccc tgtttctgag gatgaaggaa tgattgctgc
    43021 agtgcaaaat ggctctctta atttagaaaa actagaagct atgacggcta tctgttctgt
    43081 tggattggat atgattgcca tcccagaaga tacgcctgct gaaaccattg cggctatgat
    43141 tgcggatgaa gcagcaatcg gtgttatcaa catgaaaaca acagctgttc gtatcattcc
    43201 caaaggaaaa gaaggcgata tgattgagtt tggtggtcta ttaggaactg cacccgttat
    43261 gaaggttaat ggggcttcgt ctgtcgactt catctctcgc ggtggacaaa tcccagcacc
    43321 aattcatagt tttaaaaatt aagaaaatag gagaaatttt aagttctatt taagattaga
    43381 cgtgtatact ataatcat
//
LOCUS       DAVKXA010000012        43136 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKXA010000012 DAVKXA010000000
VERSION     DAVKXA010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.012"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..158
                     /locus_tag="VW883_000714"
     CDS             <1..158
                     /locus_tag="VW883_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NINE protein"
                     /protein_id="HEV0273892.1"
                     /translation="WIGGHHFYAGYNRKGFLYLLFSFTFIPMLLALFQVISALLKTPD
                     SNGKILV"
     gene            178..408
                     /locus_tag="VW883_000715"
     CDS             178..408
                     /locus_tag="VW883_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273893.1"
                     /translation="MDYAQDYLDDILVRMAYHSSGIEGNTISLPETVSIILEKSIIVM
                     FNIANTSQRINVNAYTYFQNKNKKVQKKRQKS"
     gene            1300..2466
                     /locus_tag="VW883_000716"
     CDS             1300..2466
                     /locus_tag="VW883_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0273894.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKDGSTVYKTVEIKTYAELVENWLETYCHTVKKATLTIIKSRLNNYVL
                     PAFGEYKLDKLTPPVIQKQVNQWAKEYNQLGKGYQEYPQLNSLNKRILKYAVSLQVIP
                     FNPARDIIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLQNGTLDVNKTLNCEKEVTTPKTKSSIRVIDLDNKTVLMLRLY
                     KNRQAQVGREIGLTYEKVFSNSFDEYRDARALRSRLEKHLKLSDCPRLTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHSQISITMNTYSHLSKDNKKNATSFYEKAIEKLKSS"
     gene            complement(2729..2983)
                     /locus_tag="VW883_000717"
     CDS             complement(2729..2983)
                     /locus_tag="VW883_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0273895.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(3003..4844)
                     /gene="typA"
                     /locus_tag="VW883_000718"
     CDS             complement(3003..4844)
                     /gene="typA"
                     /locus_tag="VW883_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0273896.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            5006..5731
                     /locus_tag="VW883_000719"
     CDS             5006..5731
                     /locus_tag="VW883_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0273897.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMNLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSIGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(5767..5997)
                     /locus_tag="VW883_000720"
     CDS             complement(5767..5997)
                     /locus_tag="VW883_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273898.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFRK"
     gene            complement(6086..6466)
                     /locus_tag="VW883_000721"
     CDS             complement(6086..6466)
                     /locus_tag="VW883_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0273899.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(6466..6735)
                     /locus_tag="VW883_000722"
     CDS             complement(6466..6735)
                     /locus_tag="VW883_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0273900.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLKAEAVLRREHKVELDYIEKNGEKN"
     gene            6799..7707
                     /locus_tag="VW883_000723"
     CDS             6799..7707
                     /locus_tag="VW883_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0273901.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(7761..8516)
                     /locus_tag="VW883_000724"
     CDS             complement(7761..8516)
                     /locus_tag="VW883_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0273902.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(8537..9466)
                     /locus_tag="VW883_000725"
     CDS             complement(8537..9466)
                     /locus_tag="VW883_000725"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0273903.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(9481..10104)
                     /locus_tag="VW883_000726"
     CDS             complement(9481..10104)
                     /locus_tag="VW883_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0273904.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(10097..11335)
                     /gene="hflX"
                     /locus_tag="VW883_000727"
     CDS             complement(10097..11335)
                     /gene="hflX"
                     /locus_tag="VW883_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0273905.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTILSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(11328..12212)
                     /gene="miaA"
                     /locus_tag="VW883_000728"
     CDS             complement(11328..12212)
                     /gene="miaA"
                     /locus_tag="VW883_000728"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0273906.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVSHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            12333..12503
                     /locus_tag="VW883_000729"
     CDS             12333..12503
                     /locus_tag="VW883_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0273907.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(12551..13390)
                     /locus_tag="VW883_000730"
     CDS             complement(12551..13390)
                     /locus_tag="VW883_000730"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0273908.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKFAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(13487..14446)
                     /locus_tag="VW883_000731"
     CDS             complement(13487..14446)
                     /locus_tag="VW883_000731"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0273909.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(14573..15572)
                     /locus_tag="VW883_000732"
                     /pseudo
     CDS             complement(14573..15572)
                     /locus_tag="VW883_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(15622..16239)
                     /locus_tag="VW883_000733"
     CDS             complement(15622..16239)
                     /locus_tag="VW883_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0273910.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(16240..17961)
                     /gene="pabB"
                     /locus_tag="VW883_000734"
     CDS             complement(16240..17961)
                     /gene="pabB"
                     /locus_tag="VW883_000734"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0273911.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(18035..23647)
                     /locus_tag="VW883_000735"
     CDS             complement(18035..23647)
                     /locus_tag="VW883_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0273912.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTIEVVPDDTKYVDEEV
                     VERQGSKGVQITKTTYETVEGVETDKVLSTTTEVKTPAVPKVVKKGTKPVEGTTVETR
                     EEVIPFETKEQEDDTLKRGTRQVVQKGVEGKKQITETYKTIRGEKTNEAPIVKETVIE
                     QPQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVEIKSIKVALKDNT
                     GTVIKEVTVEENNLNATLDNLKYYQGYTLSTTMVYNRGEGEETEMLEDKEVQLDLKKV
                     EIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKTTRLAVSSVEEVV
                     VDGKTLYKVVAKAPDLVQRREDDTLSEEYVHYFEKQLPKVDNVYYSFNELITDMQKNP
                     TGTFKLGADLNAANTPTPSKSYVTGEFKGKLSSVDGQHYTIHNTARPLFNNIVGGTVK
                     NINLNNVNIDMPWADQIASVANVIKGGSLIENVKVKGNVLGRNWVSGFIDKIDSGGRL
                     VNVAFIGNVTSVGDGDKFLTGIVGENWKGYVEKAYVEANIKGKRAKAAGISYWSQNSG
                     DNNAVGRDGAIKKSVVKGSIDVEKPIEVGGAVGSLNYLGYIEDTVAMMKVKNGEIFYG
                     SHDIDTDPYYTGERVNRNFIVDGVSEGKSSYTYSKQQKRIKSISQEEADKKIKELGIT
                     ADKFTIIDPIVNKLNNIKQKADTYKDTQDYKADRELAYRNIEKLQPFYNKEWIVDQGN
                     KVPSNSKLLTTEVLSVTGMKDGQFVTDLSEIDKIMIHYADGTKEEKSVSPKPTSNVEQ
                     VKEYGITDLGDVVYTPNMVVKDRAQLLSDVKAKLDTITLESPEVRAITGNVGALYLEE
                     SFAEVKGNLDKLVKALVENEDHQLNSDEAAIKAFLKKVEDNKAKIMMALTYLNRYYGI
                     EYGDLNIKNIMMFKPDFYGKIPSVIDRLIRIGSQEKNLKGDRTQNAYREIIAGDTGKG
                     DLRSFLDYNMRLFTNDTDLNDWFIHSAKNVYVVEPETTNPDFKNKRHRVFDGLNNNMH
                     ARMILPLLNLKKAHIFMISTYNTMAYSSFEKYGKNTEAEREAFKERINYVAKAQQTYL
                     DFWSRLALPNVRDRLLKSQNMVPTPVWDNQAYAGIKDANRRGYGTDGKVATPIRELFG
                     PTDRWHQINWNMGAMAKVYGKPYEDEQVFFMVTNMLEDFGISAFTHETTHINDRMAYL
                     GGHGHRPGTDLEAYAQGMLQTPDKSTSNGEYGALGINMAYHRQNDGNQWYNPDPDKLQ
                     SREQIDHYMKNYNDALMMLDHLEADAVLPQLNGNTSRWFKKMDRQYRSGNSGHQFDKI
                     RELTEDEKKVAINTIDDLITNNLITKHGAPGDGTYNPTDFRSAYVNMNMMTGIYGGNT
                     STGAPGAASFKHNTFRMWGYFGYENGFVGYASSKYQNAANKENNRMLGDDFIIKKVSN
                     GRFTNLEDWKKEYYKEVKAKGEKGFTAIEIDGKQITNYAELKVLFDKAVEADLAGGGT
                     AKTVELKSKVFKALLKNSDGFTGNLFKA"
     gene            complement(23669..24232)
                     /locus_tag="VW883_000736"
     CDS             complement(23669..24232)
                     /locus_tag="VW883_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0273913.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(24348..26039)
                     /locus_tag="VW883_000737"
     CDS             complement(24348..26039)
                     /locus_tag="VW883_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0273914.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(26036..26773)
                     /locus_tag="VW883_000738"
     CDS             complement(26036..26773)
                     /locus_tag="VW883_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0273915.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSFLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(27041..28153)
                     /gene="msrB"
                     /locus_tag="VW883_000739"
     CDS             complement(27041..28153)
                     /gene="msrB"
                     /locus_tag="VW883_000739"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0273916.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(28164..28730)
                     /locus_tag="VW883_000740"
     CDS             complement(28164..28730)
                     /locus_tag="VW883_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0273917.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHRGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(28750..29460)
                     /gene="ccdA2"
                     /locus_tag="VW883_000741"
     CDS             complement(28750..29460)
                     /gene="ccdA2"
                     /locus_tag="VW883_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0273918.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYFTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(29671..30531)
                     /locus_tag="VW883_000742"
     CDS             complement(29671..30531)
                     /locus_tag="VW883_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0273919.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(30710..32764)
                     /locus_tag="VW883_000743"
     CDS             complement(30710..32764)
                     /locus_tag="VW883_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0273920.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(32776..33030)
                     /locus_tag="VW883_000744"
     CDS             complement(32776..33030)
                     /locus_tag="VW883_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273921.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKDQKEIFESCCKKD"
     gene            complement(33023..33580)
                     /locus_tag="VW883_000745"
     CDS             complement(33023..33580)
                     /locus_tag="VW883_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0273922.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALKKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSI
                     ITRPQTTIEALGKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(33564..34520)
                     /locus_tag="VW883_000746"
                     /pseudo
     CDS             complement(33564..34520)
                     /locus_tag="VW883_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            34612..34971
                     /locus_tag="VW883_000747"
     CDS             34612..34971
                     /locus_tag="VW883_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0273923.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            35183..36040
                     /locus_tag="VW883_000748"
                     /pseudo
     CDS             35183..36040
                     /locus_tag="VW883_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722232.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(36288..42989)
                     /locus_tag="VW883_000749"
     CDS             complement(36288..42989)
                     /locus_tag="VW883_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0273924.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKCIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDSYETKDLTVEWEEVPAEN
                     LTKAGQFTIRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
BASE COUNT        12407 a         9587 c         7923 g        13219 t
ORIGIN      
        1 gttggatagg tggtcatcat ttttatgcag gatataatag aaaaggattt ttatatctac
       61 tattcagttt cacttttatt ccaatgcttc ttgcactttt ccaagtaatt tcagcattgt
      121 taaaaactcc tgattccaat gggaaaattt tagtttaatt ttacagaaag gagaatcatg
      181 gactacgctc aagactacct ggacgatata ctggtacgca tggcctacca ttctagcggt
      241 attgaaggga acactatttc cctacccgaa accgtcagca ttatcttaga aaaatccata
      301 atcgtaatgt tcaatatcgc caatacttcc cagcgaataa atgtcaatgc ctacacttat
      361 tttcaaaata aaaataaaaa agtacaaaaa aagcgacaaa aaagttgatt tttaataaaa
      421 aaacgataga gttatattag aaagtcgctt gtaattctga tatgtctgcg tatttttcgt
      481 aagttgccta ttgggtaacc tgctatcagt taagggcttt tatattttac aaaaaaatca
      541 gtgtatcggc ttattatgtt ggtacacttt tctttttact acactagttt tctacaacaa
      601 aaaaaaagac aagctagctg ctgctgactt gtctaatatc gcctgaactg aaataacggg
      661 aaagattcag gcggttacat gactagttta ccatattatc cagaaaaaca aaaaaggtaa
      721 gtcaataccc tgtcatcagg ctataactct ctaatgaagt ataatgcggt ataatttaga
      781 caattttcaa cactttggca ttttagaaac gcttaaagcg ctctaaacaa tatcaaaaaa
      841 aataaaactc ttgaaatatt ggggcttgta tgctagaatg aaagcataaa gggaaaaaca
      901 gtgcttctag catatgtaac taaaaagccc caccgttaca gcgatggggt tttttgctac
      961 cctcttaaag ggttaaatgc tacttgctac gtctctttat ccatagcttg aaaagctcag
     1021 ataagacgtt aacaagtaac ggagctagaa aaagggaaaa caactctagc atatataaca
     1081 cctcccttct ctaaattgag gaggcgaaaa cattatatca aaaacaccca tcacaaacaa
     1141 gcccatataa gtcccatatc tgccttattc ccttttctgg tacaatttac cgtctgacta
     1201 attaaaatcg aaaatagggg tattctcgta gcccctcgca tggtataaac tcaaaatctt
     1261 ttctaattgc ttgcctgctg atggaagagg agtaaaacca tgaaaataac agaatacaca
     1321 aaaaaagacg ggtctacagt ctatcgctct agcgtctatc ttggtatcga taccgtaaca
     1381 ggtaagaaag tcaagacgac tatatcaggg cgaaccaaga gagaactcaa agccaaagcg
     1441 ctacaggctc aaatagattt tgaaaaagac gggtctacag tatataagac ggtggagata
     1501 aaaacttatg ccgaactggt ggagaattgg ctggaaacat actgccatac agtcaaaaag
     1561 gcaacactta caataatcaa gagtagacta aataactatg tacttccagc ctttggagaa
     1621 tacaaactag ataagctaac acccccagtt attcaaaagc aagttaatca atgggcaaaa
     1681 gagtacaatc aactaggcaa aggttaccaa gagtatccgc aacttaactc gctaaataaa
     1741 cgaatactta aatatgccgt atccttgcaa gttatcccct tcaacccagc ccgtgatatt
     1801 atcgtgccac gtcgtaagga aaaagaaggg caaaaactga aatatctgga tgatgataac
     1861 ttaaaaaaat tcttgactta cctggagcag ctgccaaaca cttacaaaaa tttctacgat
     1921 acggtgctat ataagacgct tttagcgact ggtttgcgta ttcgtgagtg tttagccctc
     1981 aaatggtctg atattgactt acaaaacggt acactagacg taaataagac tctaaactgt
     2041 gaaaaagaag tcactacccc taaaactaaa tcaagtatta gggtaattga cttggataat
     2101 aagacggtgc tcatgctgcg actttacaaa aatagacaag cgcaagttgg tagagaaata
     2161 ggcttgactt atgaaaaagt attttctaat tcctttgacg aatatagaga cgctagggcg
     2221 cttaggtcaa gacttgagaa acatttaaaa ctttctgact gccctcgttt aacgttccac
     2281 gctttccgcc acactcacgc tagtatcttg ctcaatgccg gactgcctta caaagaaata
     2341 caaacaaggc tagggcattc tcaaatatca ataaccatga atacatatag ccacttgtcc
     2401 aaagacaaca agaaaaacgc tacttcattt tatgaaaaag ccattgaaaa attaaaaagt
     2461 tcctaaaaag tccacaaatt ttataaatcg gttatgaatc aagccacaaa taccgctata
     2521 ctagggaatt taccccctat acttgaaata aagcgcattt caaaataata tgcaaccagt
     2581 actaaccaaa tataaaatag atgccattaa cgaattttat tcaagttttt cccattcata
     2641 ctatacaagc aaaagagatg gtgttaacta aaaagcaatt caaactatta taaaattcct
     2701 agcaaaaaga gagccgaaac tctctttttt atcttctttt actttttttg actggcatga
     2761 gtgtgatgtc tctcacacta aagtaagcta ggatcaacat ggctattgct aggaatattt
     2821 ctgttggtaa ttgaaaaatt ttcagaaaag atagaaccaa taaaatcaag agtgccacta
     2881 aaatacatac catagcgacg atattgactg tccctttaat gctttctggt gtcgcaaata
     2941 catagagtag gagcagtaaa attcctagga ctaaatagac catctttctc tctttctagc
     3001 tcttattcag ctgatttttt cttcttgtta gctttctcac gctctgcttt gttaaggatt
     3061 tgtttacgca aacggataga ctcaggcgtt acttccatgt actcatcgtc gttcaagaac
     3121 tcaagagact cttcaagtgt caagatacga ggcgtcttga taacagctgt ttggtcctta
     3181 gtagctgaac gaacgttggt catttgtttt gccttcgtga tgttaactgt caagtcattt
     3241 tcacgagagt tttcgccgat gatcattcct tcataaacct cagtacctgg gttgacaaag
     3301 atcgtaccac gttcttcgat agacatgatt gagtaagttg tagccttacc agcatcgata
     3361 gaaacaaggg caccacggtg acgtccacca atttcccctg gaatcaatgg caagtactgg
     3421 tcgaaggtat ggttcatgat accgtaacca cgagtcattg acaagaactc agttgagtat
     3481 ccaatcaaac cacgcgctgg aacaaggaag accaaacgag tttgaccatt accagttgaa
     3541 atcatatcca acatttcacc tttacgttca gaaaggcttt ggataacaga cccttggtat
     3601 tcttctggag tgtcgatttg tacacgttca aatggttcac atttaacacc gtcgatttct
     3661 tttacgataa cttctggacg agatacttga agttcatagc cctcacgacg cattgtttcg
     3721 ataaggattg acaagtgcaa ttctccacgt cctgaaacag tccatttatc tggtgaatca
     3781 gttgggtcaa cacgaaggga aacgtctgtt tgcaattctg cctgcaagcg ttcttccacc
     3841 ttacgagaag ttacccattt accttcttta ccagcaaatg gtgagttgtt gaccaaaaaa
     3901 gtcatttgaa gagttggctc atcgatgtgt aggattggaa gagcttctac tgcatctgtc
     3961 ggagtgatgg tttcaccgac aaagatgtct tccatacctg aaacggcaat caagtcaccc
     4021 gctttggctt cttggatttc acgacgttcc aaaccaaaga aaccgaagag ttttgtaaca
     4081 cggaagtttt tagttgtacc gtcaagttta gaaagggtaa cctggtcccc aaccttaact
     4141 gtaccacgga agacacgacc gataccgata cgtccaacaa agtcattgta gtccaaaagt
     4201 gacacttgaa actgcaaagg ctcatctgag ttatctactg gagctgggat atggtcgata
     4261 atcgtgtcaa agattggtgc catagtcgct tcttggtcag ctggatcatc tgacaatgaa
     4321 gaagttccgt tgatcgctga agcataaacc actgggaaat caagctggtc gtcatctgca
     4381 ccaagctcga tgaaaagttc caagacttca tccactactt ctgctggacg agctgatggc
     4441 ttatcgattt tgttaacaac cacgattggg acaaggtctt gttccaaggc ttttttcaat
     4501 acgaaacgag tttgtggcat ggttccttca taggcatcta cgaccaagac aacaccgtca
     4561 accattttca tgatacgctc aacttctcca ccaaagtccg cgtgtcctgg tgtgtccata
     4621 atgttgatac gagttccgtt gtaagcaacg gcagtgtttt tagcaaggat ggtaatccca
     4681 cgctcttttt cgatatcgtt tgagtccata gcacgctctg ccaattcagt acgtgcatca
     4741 agcgtttctg attgtttcaa taattcgtca accagggttg ttttaccgtg gtcaacgtgg
     4801 gcgataatcg caatgttacg gatatcttct cttaattttg tcatgatttc ctctataata
     4861 ttcaaaattt attttctaac tgaacgatta taccataatt tcaaataaat aacataactc
     4921 aagcaagtgt aaatgttttc actccgcttt tcttttcacg tcaagccttt tcaaagcaag
     4981 cgacttatga taagataggc acagtatgcg tttagataat ttattagccc aagaaaaagt
     5041 tagccgaaag gccatgaagc aagcactcct cagaggggaa attctagtcg atggttgccc
     5101 agcccgctcc ctagctcaaa atatcgatac aggactacaa gaactccttt ttcaggatcg
     5161 aatcattcaa ggctatgaac acacctatct tatgcttcat aaacctgctg gtgtcgttac
     5221 agccaacaaa gacaaggaac ttccgaccgt catgaacttg cttccatctg acatccagtc
     5281 tgacaagctc tatgccgtcg gccgactgga ccgagataca acaggactcc ttctcttgac
     5341 cgataacggt cccttgggct tccaactcct ccatccccaa tatcatgtcg ataagactta
     5401 tcaagttgag gttaatggac ttctaacacc tgaccatatc caaacctttc aaaaaggaat
     5461 tgtcttttta gatggcacta tctgtaaacc tgcaagacta gagattctat cagcaagtcc
     5521 ttccctcagt caagcctcta tcaccatttc agaaggaaaa tttcatcaaa tcaagaaaat
     5581 gttcctctcg attggtgtta aggtgactaa cctcaagaga atccaatttg gggacttcac
     5641 attgaaccca gatttagcag aaggtaacta ccaccctttg aaccaaaaag agttacaaat
     5701 cattaaaaac tatttagaga tgagtcgata aaacaaaaaa agctttaaaa ctaaagcttt
     5761 tttcttttat ttccgaaaaa ttaaggcgat tgctacaatc cagttaacta cagaaatcac
     5821 aattcctaag atattaagaa tcttttctat tttatagtct aattgtgact ctttttggta
     5881 tgaaatagcc aagaccaatc ctatgatacc caaaatcagg cctacaattg gaaataacaa
     5941 accaagaata atcgacaaga tacccacaaa aagtggattt ttcttctttt ctttcatgtt
     6001 ctaagaactc tttaaatttt atacaaatta attatactat aaaacaatat cttcatccta
     6061 tcattcgact aatttggaaa taaggttagc tagtcttcac tttccctttc caagaatcca
     6121 agccataaga aaggatataa atctcagaaa aaccttgttt tttcaagtaa agagctgcat
     6181 ttgtaactcg ttgcgcacgt tggttttcgt agagaaggac aggtttatct ttacgaaggg
     6241 ctgcaagact agttttcaac tgacttgaag gaatattgcg tgcaccaagg atatgttttc
     6301 tgtggaattc tgctgggtcg cgcaaatcaa tcaattgacc cgtacgaatc aaggcttcaa
     6361 actcctcatt gtccacaatt ttagccgcac ggcgaatacg aagatagtta aagcccatcc
     6421 acgccaacat tgctagtata agtgcccaca aaatccaagt aaccattagt tcttttctcc
     6481 atttttctca atataatcca attctacctt gtgctctctg cgaagaactg cttctgcctt
     6541 tagatagtct aatttatcca tcaaccctgc atcgtaaatc cgagatagtt ccaacttcat
     6601 cagttcaata tcatataagc gttttcccat gtaaacaata ataccaaatc gtttgaggaa
     6661 ttgctgcaca tcatagaatg ttttcataag actcattcta gcaaaatttt gtgttttttt
     6721 caagaagaga ctcacacaat gctccttatt ttcctatctt ctttagcgat tctaaggcaa
     6781 gtatggtaca ataaaaacat gagaattcaa caattacatt atattatcaa aatcgtcgaa
     6841 actggctcca tgaatgaggc agccaagcaa ctctttatca ctcagccaag tctctccaat
     6901 gcagtgcgag atttggaaaa tgaaatgggc attgagatct ttatccgcaa tcccaaggga
     6961 atcaccttga cccgtgatgg gatggagttt ctctcttatg cccgtcaggt tgtcgagcag
     7021 acccagcttc tggaggaacg ctataaaaat cctgtcgccc accgcgaact atttagcgtt
     7081 tcgtctcaac actatgcctt tgtggtcaat gcctttgtct ctttgctcaa gaaaagcgat
     7141 atggagaaat acgaactctt ccttcgtgaa actcggactt gggagattat cgacgacgtc
     7201 aagaacttcc gcagtgaggt cggggtcctc ttcttaaaca gttacaaccg tgatgtttta
     7261 accaagatgc tggatgacaa tcacctgcta gcccaccatc tcttcacagc gcaaccgcat
     7321 atctttgtca gcaagaccaa ccctctggca aagaaagaca aggtgaaact gtctgatttg
     7381 gagaatttcc cttacctcag ctatgaccaa gggacgcaca actccttcta cttttcagaa
     7441 gagattcttt ctcaagaaca ccacaagaaa tccattgtgg tcagtgaccg tgccaccctc
     7501 tttaatctct tgattggttt ggatggttat accattgcga cagggatttt gaacagcaac
     7561 ctaaacggag acaatatcgt ttctatccca ctggatattg atgacccgat cgagctggtc
     7621 tatatccagc atgagaaaac cagcctatct aagatgggcg aacgctttat agactatctc
     7681 ctagaagaag ttcagtttga tagttgagaa atgataagaa ccaatatgta ggctagcaac
     7741 aacctgcaca ttggttcttt ttacttataa ttaaaagttt cccctgccaa cttatcagct
     7801 agcttaggaa agagggtata aaacttatga gctaggttca acaaaatcgg gagattgagt
     7861 tctcgtttgt tttttcctat aatcttgaca atctttttag ccactgcatc tggttctagc
     7921 aggaagcggt caaccgattt aagataagtt ccatctgggt cagcttggtc aaaaaatcct
     7981 gttcggattg gacctggatt gactgttgtc acatagactc catagggcat aagttcgagt
     8041 cgcagagcat ttgaaaaacc aatagccgca aacttggtcg ctgagtaaag actagacttg
     8101 ccagtagcta ttagacctgc catgctgacg atgttgatga tatgcccttt gctgctttcc
     8161 ttcatacgag ccgcaaggtg acgagacaga ttcatcaggg caaaggtatt gacctcaaac
     8221 atctggtgaa tgtctttatc agcaatttgg tcaaatccct caaaaatccc gtaaccagcg
     8281 ttgttaatca agacatcaat cttgccatag cggagataaa gatcagttac cagagcttct
     8341 agggctgaat cgtcggtaat atcaatttca atcaattctg catgggaata atttccgtag
     8401 agttgggcta atttttcctt atttctacca agcaagatga gttggtcatt gggcaggagt
     8461 ttgaccattt cttgagctag accaccgcta gctccggtaa tgagaatagt aggcatactt
     8521 atcctttctg tgactgctag atttccactt cttccaagtc tttgaccaca tggacatttt
     8581 caaaaattgt ggcagcgtct ttcttgagtt tgctaatatc ttttgagagg aaacgggcac
     8641 tgatatggtt gagtaggagg cgtttggcac ctgcttctac cgctacttgt gcagcttgca
     8701 tattagttga gtgaccatgg ttacgagcaa ttttttcatc acccttgcca taagtggact
     8761 catgaactag gacatctgca ttgacagcca gacgcacact ggcatccgtt tttcgagtat
     8821 ctcctaaaat agtgataatc ttacctggac gtggcgctga gatatagtct gctgccttga
     8881 tttcagttcc gtcttccaaa acaagatcct ggccgttttt gattttacca aaaagcgggc
     8941 cgaacggaac accagcagcc ttaagttttt cagcatccag cgtcccttct agatcctttt
     9001 gcatgacacg atagccaaca cagaaaatag tgtggtccag ctcctctgca tacacagtga
     9061 atttatcggt ttcaagaatt ttacctagag aatcttggtc aaactcatgg aaatgaatgc
     9121 ggtagggcag acgagaacct gacacacgaa ggctggttaa gacaaatgac ttgattcctt
     9181 gaggtccgta gatttccaaa tctgtctgct cttcattggc ctgaaaggca cggctagaaa
     9241 ggaaacctgg caaaccaaaa atgtggtctc catgcagatg ggtaataaag attttgctga
     9301 ccttacgtgg tcgaattgtg gtttccagaa tgcgattttg cgtaccttct ccacagtcaa
     9361 agagccaaac ttcgttaatc tcgtccaaaa gtttcagggc gagacttgaa acgttgcggg
     9421 ctttagaggg ctgaccagcc cccgttccta aaaattgaat atccattcga tactttctaa
     9481 ttaatcaata tataacatgg ctgtgcggtt ttccgatcgg aaatagcgtt tgccagaaaa
     9541 agcagcagct tcttgcaata aatcctcttg gctgtagcct ttgagacgtt ttcgaccatc
     9601 agccaatctt tccaaatcag tcaaagctgt gagactttct aggctgacaa cttcctcgtc
     9661 cttgacaggc ttcatgtaaa tcttaccaga ctcttcaaag actaattgat gggagaaaat
     9721 ttgcgcaatt tcaaagagca agtcatccga gattttctcc tcattttcag agaaaatccg
     9781 accaaagccg tcactctcat aacaaaaacc aaaggattta ccagacagat taagccgaat
     9841 aaaaggctta ttttctaggg tgaaacttgg ctcagtattg taaagattca gttcctgact
     9901 gagttctgca aaataatccg tcgcagcctg aggacttttt ttctgataga gttctgcaaa
     9961 gtaggcatta acaacacttg gcggaggtgt aataagtgtt aactgctcct gctctgtttt
    10021 accagctaga agctgatcca gatagacctt gtccagactt gtataacctc catactttag
    10081 agccaaagtt ttaatatcag tcataaaatt cttctaacct ccatttattt ttctcggaaa
    10141 tgtagcctgt aatcacttcg ccgtcttcct gataatcacg ttcttccaga attgcaacac
    10201 tctctaaatc atgaatcttg taggactttg aaaaaggcac tcgcagggta aatgcttcaa
    10261 aaatttcctt aatcttatct agcaataatg cttgcaagtt ttcacgactg tcctcagact
    10321 tggcagaaat gagggtatat ggcgtttggg taggcgtgaa atcctccacc aaatccgctt
    10381 tattataaag cgtcaagtga ggaatatctt ccatgtccag gtctttcatg atggagagaa
    10441 tcgttttttc atgttcctcg tggtaaggat tgctagcatc gataacatga accagaaggt
    10501 ccacatgctt gctttcttcc aaggttgact tgaaactgga caccaactct gtcggcaaat
    10561 cttggataaa gccaacggta tctgtcaaag ttacttggag gttgcctccc agatgaatac
    10621 tcttggttgt cgcatccaga gtcgcaaaga gctcatctgc ttcatactgg gtcttactgg
    10681 tcaagatgtt catgatagtt gatttcccag cattagtata accaatcaaa ccaatcttaa
    10741 aagtgctaga ctccaaacgt ttttctctga cagtcgcacg atttttctca accaccttaa
    10801 gctggcgctc gatatccgtg atttgattgc gaacgctacg acggttcagc tccagttggc
    10861 tttcaccagg accacgggaa ccaattcccc ctgcctgacg gctgagcata atcccctgac
    10921 caaccaagcg aggcaagagg tatttgagtt gggctaggtg gacttggaac ttcccttcat
    10981 ggcttcgagc ccgcatggca aagatatcca aaatcaactg catacggtca atgaccttaa
    11041 caccgagaac ttcctctaga ttgacattct gccttggggt cagacggttg ttgacgatga
    11101 cagtagtgat ttcttctgca tccaccataa gcgcaatctc ttccaactta ccagagccga
    11161 cgaaggtctt ggaatcatat ttttcacgtt tttgtctgta gctatctaca acgactgccc
    11221 ctgccgtttt cgctaaacta gccaattctt ccatggagag gtcaaaactg tccataccct
    11281 gcaattccac accaatcagc aggactcgct cctctttttt ctccgtttca atcatctaaa
    11341 aactcctcta tctggcttaa aatgcggtct tgtacaccag attctccaat ctgataaaag
    11401 gtgacctgca tgcgattacg gaaccaggtc agctgacgct tggcaaaacg acgggtcgcc
    11461 tgtttgagac tctcactagc ttcctccaag gtctgctctc cacggaaata aggaaagagt
    11521 tccttatagc caattccttt agcagcctgt acattagggg aatggtcaaa cagccacttg
    11581 gcctcatcca aaagcccagc ctcaaacatc aaatccactc ggtggttgat acgctcataa
    11641 agttgactac gttcatcatc caagcagata atcagcggtt catacaaggt ctcttgattt
    11701 tccaaatcct gaccaaaatg ggcaatttct aaggcacgca tagcacgacg acgattaaac
    11761 tggggaatct caaggcctgc ttgatccacc aaatgggcta attcctcatc tgaatatggc
    11821 tccaaactag ctcgataagc taaaatctcc tcatgaggag tctccccacc taggtggtaa
    11881 ccttctagca agctctggat ataaagtcca gtcccaccgg cgataatggc tagcttgcca
    11941 cggctgtgaa tatcctcaat agtcatctta gcttctgaaa caaaatcaaa agccgagtaa
    12001 gactcggtta tctctctaac atcgattaaa tgatgagaaa cagctgcctg ctcttctgga
    12061 ctagccttgg ccgtcccaat atcaagtcct cgatagactt gttggctatc tccactaacc
    12121 acttcgccat taaaacgctt tgcaacttca atagctagag ccgtctttcc aacagcagtc
    12181 ggtccaacaa tcacaattat ttttgttttc atcttttttc cttgaaaaat tcccattttt
    12241 tcgttactat tattataaca caaaaaggtc agtcagaaaa atgtgacctc ttgaggaggc
    12301 tggctgattg agaatataaa ggaggaagac tcatggctaa aggattcgct aaaggtcttg
    12361 taacaggtgt cgcaggaact gtcgctgccg ttgcaggtgc agtatacgca tttaaaaaga
    12421 aagtaatcga accagaagag caaaaagcag ctttcatcga agaaaaccgt aaaaaagcag
    12481 ctcgtcgccg cgtatcacgt taagaaacaa aagaagttgg gattattctc aacttctttt
    12541 ttctattctt ttaaatagct aggtcaaact tcaactgtgg cttaacaggg tcataatcca
    12601 ccaactcaaa atcttctgct ttgatatcaa agaaattagt cccatcagga acatttaaaa
    12661 ccaagcgtgg ttggcagttt gacggctccc gacggagcaa ttcctgagct tgttcaaatt
    12721 gattatcata gatatggagg ttgttgatga agtagaagaa cttcccaacc ttccagccaa
    12781 aatgtttggc aatcatcatc tgcaaagcca catactgcat agcgttgatg tggtgggcca
    12841 ccagcatatc attggagcgc tgggtcaagg tcgcatccag atagatttcc ccatcaacac
    12901 gccggacatc aaacatggtc tgaaaggcgc acgggagcag cccatctgtt tcttcgaaag
    12961 cttggtaatc ccagagcgaa ataatattgc ggcggttcca aggattggtt tccaactgtt
    13021 tgagaagctt attgataatg tcgtgtttct taacaacggc accatagcgc tcaccaatgg
    13081 ttcccgtgtc tccaacttcc cagtcattcc agtagtgaac attgtacttg tcattaagca
    13141 cttctaagct atttgactgg tcttggtaaa tccagagaac ttctttgatg gcgaatttga
    13201 ttgcaatggg acgcaaggtt gtgataggaa attctccttt agataagtcg tactcggaaa
    13261 aggcaccagt tacatactta gaattagcaa cagtcccatc cttgtactta ggacgagcct
    13321 gctctgagaa aacaccttcc tttagaatgc gttcaatatt ctctttaaaa atcgtatctg
    13381 cttttgtcat ttcgtttcac ctcattcatt gtcctaacta gtatagcata aaaaataaaa
    13441 gaggaacatt actaactcta ggttagcatt ttcctctctc attatcttat tgcaatacaa
    13501 gtgatgctgc tccgataact ccagcgtcat ttcctagagt tgcaagagct aatttagtag
    13561 atgtgcgtac ttgtgggaaa ctattttcat cgtaaacttt ttgaacacct tgtagaagga
    13621 attctcccgc agctgacaca ccaccaccga tgacgattgt tgatgggttt aggattgaac
    13681 caatgttagc acaagcgatt cccaagtaac gtgagaagtt acggtaaaca atcaaagcaa
    13741 ggtcgtctcc ttcttttgcg agatcaaaga cagtcttagc agttacttct tctccgttat
    13801 caatcaagcg tttcaaggct gcatcgcctt cgtattcatc ggcatagcga cgagtcaagt
    13861 tgacaatccc tgttgctgaa gcaactgtct caaggcagcc tttcttaccg caagtacatg
    13921 cgattggctg gtcaaagtca acagtgatgt gaccaagctc acctgctgca ccagcaacac
    13981 cgtgaagcaa tttgccttct gcgacgatac cgccaccaac accagtaccg agtgtcataa
    14041 agacaacgtc tggttggtta tctccagcac ccatccagcg ctcaccaaga gctgctacgt
    14101 tggcatcatt atcgatgaaa aatggaatgc ccaaagcttt ttcaatcttt tgtttgattg
    14161 gttgaagggt tttccagttc aagttgtagg caccgataac agtccctttt tcacggtcaa
    14221 ccacacctgg tgatcccatt ccaatgcctt ggaagtccgc tgctgccaat ccaagcaagt
    14281 ccaaacgatg ttgaatagac tcaatcatat catcaacgat atgacttccc tcatccaaaa
    14341 tgtttgtctt gattgaccat tttccttgga tttctcctgc tgttgttaag attgcaaatt
    14401 tgatagaagt tccaccaagg tcaatcccaa taatcttttg actcatcata ttctcctttt
    14461 tcattgtgta gtaattgaaa atgcttacag tactagtata tcaaaattca ttcacttatg
    14521 caaaggtttg cgtaagtgaa ttataaggaa ttttttcgcc taccagtatc tgttaatcat
    14581 ctaaatgatc aatggcatat tgagctgcat catttgaaaa tttatcaaaa tcagaagtta
    14641 attgtctata catacgtttt ttttgacatg tggaataacg aattataact ttttgccttt
    14701 cctaaagcag cagaatattc actattgcta tcattactag aagaagctgt acttgcttga
    14761 ccttccttcc aaactccgtc agcgccaaca taataacgtc caccatcaac ccattcattg
    14821 acagccattt taccatccga ttttagatag taatttcctt gccatgtact gtaagcataa
    14881 gaaccatctg atgtcaaata ataccaagct tgataggtgg caacataaac ccattcacct
    14941 ttagccattt taccatctga tttcaaatag tagtttcctt gccatgcatt gcgagcatat
    15001 gaaccatctg atttcaagta ataccatgct tggtaagaag aatcataaac ccactcacct
    15061 tgtgccattt taccgtttga tttaaggtaa taagctcctt gccatgcatt ttttgcataa
    15121 gaaccatctg atttcaaata ataccaagct tgataagaag agtcataaat ccattcactc
    15181 tgtgccattt taccatcagc tttcaggtaa tagcttccct gccatgcatt tttcactaga
    15241 tttccatttc catcaaagta gtaccaagcg ccgtcctgct taacccaacc acttgttgtt
    15301 gctgaacttg tgttgatttg aatagccgtt gactgttttg ctttaaaagc acccttagga
    15361 gcatttttca attcgcaagc cacaccatca tgatcacggt ctaacttggc agaataacca
    15421 ggttctccct cgtgaatatc cgaatagcca ttcgcccaag cttccttaca gctcgaaaaa
    15481 tggatgtttt cttccgccaa aactggttgt gaaaacaagg ctaaaattgg caacgtcacc
    15541 agactcattt ttaaaaatag acgtttattc atttctttct cccataatta tgatatcgat
    15601 ttcaatatta ttttatcaaa cttatttcag caattcaagg aaacttctgg tcttttctac
    15661 aaactccttt ggttttgcct tattcaagac atgagggcca tcaggaatga tctgaaactg
    15721 cgaatctgtt aacagtctat ggagagcttt catagaacta agattcggtt tatctttgct
    15781 gccacaaatt agtaaggttg gataggagca agtccctgct atatccgtta aatcaagtgt
    15841 cttcaattcc tcagaaactc cgaccataag agtcttgtct gctccctgtt tttcaaatac
    15901 tcttttggga agtagtttaa aaatcagcaa ttgaagataa aataggatat tccctgctaa
    15961 tttaagcggg catcctgaca gaatcaaagc tcgaagattt ggtaaatcgt aactggaaag
    16021 ttctagtgcc agggcagcac ctaaggacaa tccaatcaaa acaaaaggtt ctgtctcttg
    16081 agctaggtgc tgataaactc gctccttagc ttgttgatag ttactaactc cagaaggaaa
    16141 taactcgata gcctcagaag gataatctgt cagtagattc cgaacttctt tccaagactc
    16201 tgctgactgc cctaacccat gcaaaaatat cagtttcatc tagttctcct caaggcttag
    16261 ttcatacaag cctctcactg cattacagcc gtaaatagct tctgcttggg ctaaatctgc
    16321 caaggtcaag actttctctt ctacctgtcc tgtttctagc aaatactgac ggtaaattcc
    16381 tggcaagatt ccaagtcgga taggcggtgt gtagagtttt ccagcgattt tcagaaccaa
    16441 atttcctata gaggtttcaa gcagttttcc tgacttattg tggtaaatct tctcttgttc
    16501 tcctaggctc aaatgcggtc ggtgagtggt tttaaagtag gtaaaggatt gattcaaagc
    16561 agcttcctga aggcagactt gggcctgaca aaagcttgta ctgagagggg ttaatacttg
    16621 acgattgact tctatctctc cagatttgct aaggctgatt cgcaagcggt aatcttgatt
    16681 agcttcacaa tcctgacact cttcctcaat cttgtgtccc aagtcttctg catcaaaagg
    16741 aaaggcaaaa taacgactag cttttctcag tctttccaga tgttgatctt caaacagcag
    16801 gttcttctgg ctgatttccc ctgtcgtaat cagttggaag cgggcttgtt tacgataaag
    16861 aactgctgcc ttttgatgaa cctctcggta ttcagattcc catgtgctat cccaagtaat
    16921 ccctccgcca actccataaa tggcttgacc tttgtgaagt tgaatggtac gaatggccac
    16981 attaaaaatc cgtcgtccat ttggaagcaa gagaccaatc gttccacaat agactccacg
    17041 cggttgaggc tccaagtcct tgataatctc cattgtcgca attttcggtg cacccgttat
    17101 ggaaccacaa ggaaagagtg agcggaagat ttcaacaagg tccacatcct ctcgcaactg
    17161 actcttgatg gtcgaagtca tctgccaaac agttgaatac tgctctacct ggcacagacg
    17221 ctccacgtgc tcgctcccaa cttcagaaat acggttcata tcattgcgca agaggtccac
    17281 aatcatcata ttttcagagc gatttttggg atcctgttcc aaccaactgg cctgttcaag
    17341 atcttcttgg tcagttaccc cacgctgagt cgtccccttc attggtcgtg ttgtcaactc
    17401 gcgatcattt tgctcaaaaa agagctctgg gctcatggaa atcactgcca tctcgtcatg
    17461 ttccacatag gcattgtagc ccgcctcctg ctctaccacc atacgattgt agatggcaaa
    17521 aggattggca cttaactttt gcttgagttg gacggtgtag ttgacctgat aggtgtctcc
    17581 ctgcctcaag tgatggtgta tctgggcaat ggccttttca tagtctgctg cagacgtcac
    17641 ttcctgccaa tttgagggca aatcaatatc ctcataagtc agaggaatag gggaggtctc
    17701 taccctatca tgaacagtaa agtaaagcag gtactctccc agtaggggat ccttgtgaac
    17761 tgctaatttt tcctcaaaag caggggcagc ctcgtagctg acatacccca ccacataata
    17821 accttgctct tggtagcttt ccacttgtgc cagcaaatct gccacttctg ctacatttct
    17881 cgtttttatc tctttgatag gctgggtaaa ggtgtatctc tcccccaaaa tcctaaaatc
    17941 aatcactgtt tttctatgca tactttaagt atagcataaa aaggcagata cagacaaagc
    18001 tgctctacct ttttactcat ctatttaata caatctatgc tttaaaaaga tttcctgtga
    18061 atccgtctga attcttaaga agtgctttaa agactttcga tttaagttct acagttttag
    18121 ctgttcctcc acctgctaga tcagcctcaa ccgccttatc aaataagact tttagttcag
    18181 cataattggt aatttgttta ccatcaatct caattgcagt aaatcctttt tcaccttttg
    18241 ccttcacttc tttatagtac tctttcttcc aatcttcaag gttagtgaat cttccatttg
    18301 aaactttctt aataatgaag tcatcaccta acatcctatt attttcttta ttggctgcat
    18361 tttgatattt gctagaagca tatccaacaa atccattctc atatccaaag tatccccaca
    18421 tacggaatgt attatgttta aatgatgctg cacccggtgc acctgtactt gtatttccac
    18481 cataaatacc agtcatcatg ttcatattaa cataagcaga cctaaagtcc gttggattat
    18541 aagtaccatc accaggagca ccatgtttcg ttattaggtt attagtaatt aaatcatcaa
    18601 ttgtattgat tgctactttt ttctcatcct ctgtcaactc acgaatttta tcgaactgat
    18661 gacctgaatt tccactacgg tattgtctat ccattttctt gaaccagcga ctcgtatttc
    18721 catttaactg cggtaataca gcatcagcct caagatgatc taacatcata agagcatcat
    18781 tgtagttctt catatagtga tcaatttgtt cacgactttg taatttatca ggatctgggt
    18841 tgtaccactg atttccgtca ttttgacgat gataagccat attaatacct aatgctccat
    18901 actcaccatt tgatgttgat ttatcaggtg tttgtaacat accttgagca tatgcttcaa
    18961 ggtctgtacc tggacgatgt ccatgaccac caagatatgc catacggtca tttatgtgag
    19021 ttgtttcatg tgtaaaggct gaaataccaa agtcctctaa catatttgtt accatgaaga
    19081 aaacttgttc atcttcatat ggttttccat aaactttagc catagctccc atattccaat
    19141 taatttgatg ccatctgtct gttggaccaa ataactcacg aattggtgtc gctaccttac
    19201 catctgtacc atatccacga cgattagcat ccttaatacc cgcataagct tgattatccc
    19261 atacaggtgt aggaaccata ttttgactct taagaagtct atcacgaaca tttggaagtg
    19321 caagacgtga ccagaagtct aagtatgttt gttgagcttt agctacataa ttgatacgtt
    19381 ccttgaacgc ttcacgttca gcttccgtat ttttaccata tttttcaaat gaactataag
    19441 ccatagtatt ataggttgaa atcataaaga tatgtgcttt tttcaagttc aataatggta
    19501 aaatcatacg tgcatgcata ttattattca gaccatcaaa aacacgatga cgtttatttt
    19561 tgaaatctgg atttgttgtt tctggttcta caacataaac atttttcgct gaatggataa
    19621 accagtcatt aagatctgta tcatttgtga agagacgcat attataatct aagaaactac
    19681 gtaaatcacc tttaccagta tctcctgcaa taatttcacg atatgcattt tgggttctat
    19741 cacccttcaa gttcttttct tgcgaaccaa ttcgaattaa tctatcaata acacttggta
    19801 tcttgccata gaaatctggt ttaaacatca ttatattctt aatgtttaag tcaccatatt
    19861 caataccata ataacgattg aggtaagtaa gtgccatcat gattttagct ttattatctt
    19921 ctactttctt aagaaatgct ttgatggctg cctcatcact atttaactga tgatcttcat
    19981 tttcaacaag agcttttact aatttatcaa gatttccttt tacttctgca aaactttctt
    20041 ctaagtataa tgctccaaca ttacctgtta tcgcacgaac ttcaggagat tcaagagtaa
    20101 tcgtatctaa tttcgcttta acatcactta gtaattgagc acggtcttta accaccatat
    20161 ttggtgtgta aacgacatct cctaaatctg taataccata ttcttttact tgttctacgt
    20221 ttgatgtagg cttaggtgat acagattttt cttcttttgt accatccgca tagtgaatca
    20281 taattttatc aatttctgat aagtcagtca caaattgacc atctttcata cctgtaacag
    20341 ataatacttc tgtagttaat aatttagaat ttgatggaac tttattacct tggtctacaa
    20401 tccactcttt attatagaat ggttgaagtt tttcgatatt acgataagca agttcacggt
    20461 ctgctttgta atcttgagta tctttataag tatcagcttt ttgtttgatg ttgttaagtt
    20521 tatttacaat tggatcgata attgtaaatt tatctgctgt gatacccaat tctttaattt
    20581 tcttatctgc ttcctcttga gatattgatt taatacgctt ttgttgttta gagtatgtat
    20641 acgaagattt accttcactt acaccgtcaa caatgaaatt tctatttact cgttctcctg
    20701 tgtaatatgg atcggtatcg atatcatgcg aaccgtagaa aatttcaccg ttcttaactt
    20761 tcatcatagc aacagtgtct tctatataac caagataatt taaacttcca acagcgccac
    20821 caacttcaat tggtttttct acatctattg aacctttaac gacagatttc ttaattgctc
    20881 catctctacc gacagcatta ttatctccgc tattttgcga ccaataagat ataccagcag
    20941 ctttagctcg cttaccttta atattagctt caacgtatgc tttttcgaca tatcctttcc
    21001 agttttctcc aacaatacct gttaagaact tatccccatc tccaacagaa gttacattac
    21061 caataaatgc aacattaact aatctaccac cactgtcaat tttatcaatg aaaccagata
    21121 cccagtttct gccgagcaca ttacctttga ctttaacatt ctcaataagg ctaccacctt
    21181 tgatcacatt tgctacagat gcaatttgat cagcccaagg catatcgata tttacattgt
    21241 taagattaat atttttaacg gtaccaccaa caatattgtt aaataatggg cgcgcagtat
    21301 tgtgaatcgt ataatgttga ccatcaacac ttgataattt acctttaaat tcacctgtta
    21361 catatgattt acttggagtt ggagtattcg ctgcattaag atctgcacct agtttgaatg
    21421 taccagtagg atttttttgc atatctgtaa ttaactcgtt aaagctatag tacacattat
    21481 ctacttttgg taattgtttt tcaaagtaat gtacatactc ttcgcttagt gtatcatctt
    21541 ctctacgttg aactaaatca ggagctttag ctaccacttt gtacaatgtt tttccatcaa
    21601 caacaacttc ttcaactgaa cttactgcca gtcttgttgt tttgttatca tgagttgtca
    21661 ctcgtaggta aagtggagca acgtctgtcg gtttttcagt aagtaagctc ttatctgttt
    21721 caacaccagc atcatccaca ctcatcaagc tagtttcttt gatgtttttg atttcaactt
    21781 ttttaaggtc taactgaact tctttatctt ctaacatttc agtttcttcg ccttcgcctc
    21841 gattatagac catggttgtg gatagtgtat aaccttgata atatttcaag ttgtctaaag
    21901 tagcgtttaa gttattttct tctaccgtta cttctttaat aactgttcca gtattatctt
    21961 ttagagctac tttgatggat ttgatttcta ccccatctgg tttattcaat gtataactgg
    22021 ctgtcgcact cttcttcaag acatctttat ctgttttaac ccattctaag gttggttttt
    22081 ctaaaccttt tgtgcctttt ttgataatct catcttgagg ttgttcaatt actgtttcct
    22141 taactattgg agcttcattt gttttttctc cacgaattgt tttataagtt tcagtaattt
    22201 gtttcttacc ttctacacct ttttgaacta cttgtcttgt tccgcgtttt aaagtgtcat
    22261 cttcttgttc ttttgtttca aaaggaatga cttcttctct tgtttcaact gttgttcctt
    22321 caactggttt tgttcctttt ttaacgactt taggaacagc aggagttttt acttctgtag
    22381 ttgtagaaag gactttgtct gtttccacac cttccactgt ttcgtaagtt gttttcgtaa
    22441 tttgaactcc tttagaccct tgacgttcaa caacttcttc atctacatat tttgtgtcat
    22501 ccggaactac ttctattgtg aaatctaatt cactttcggt agacttctca actgtacctg
    22561 ttgttacttt atattctggg tttacttctt gtactggtgc ttgaccttct ttgccttctt
    22621 cttgcgtacc tttagctgtt ttagtctcct cttttggttc tacagtttct tcagccttgg
    22681 tatctggagt tgactcttct tgtttcggtg tttcctctac agccttctct tcttcaggag
    22741 cttctggttg attttctggc tcgactggtg cctgttcgtc ttttcttggc gcgactggtt
    22801 cacctgcttg ttcaactttt gattcctcag ctggtttgtc tgatggttga ctttctggct
    22861 taactgctac tttttcctct ggttttgatt caacttctcc acctacttct tcaactggag
    22921 ctggttctgc tgaatcttct ttcccctctt ctactttagg aagggtgtcg tcagtaggtt
    22981 ttacctccga ttttggttct tcctttggac tttcttctgt tttaggtgct tcttcttttg
    23041 gagcttcctc tgtctctact acttggtttt ctgtcctagc ttgctcctga tttgttgttg
    23101 attgaggagt ctcaacttcg actacagtca cctctccagg ttttgctgag gtttcttcta
    23161 aaacagtgtc caagccaagc gttttgagga tgtcacctga tagataacca acatagcgat
    23221 agccctccat ttcaacaaca ccctctcgac tagccagtgc tagggtcgca actgggtcta
    23281 cagcccctgc actaggaaga actaccaatc ccatagttcc aactagaaag acgctagcaa
    23341 ttttctttct cttgtagatt aaaagcaagc tcccaacagt cagcaaacca aaagctgtca
    23401 aaacagatgc ttctgtccct gtttgaggca actgatcttt ttgatacacc aaaccatata
    23461 caacttcatt cctgtcaggc tttcctgtct gaattaaatc tttagcttct tgtgaaataa
    23521 tctctttatt tacatagtga taggtggctg cgtccactac agaaggagcc atcaaaaggc
    23581 ttccaagaaa tacagagcct acaactccct taatcttacg aattgaaaaa cggtcttttt
    23641 taaacacttt tatctccttt attcattctc aaaacttcct aatagcatct tgcggatagt
    23701 gcgcacgcgc acctccgatt aattttggac gactagtcag tgccgttaca tgggcatgac
    23761 caatctctct caaaataggg cgaatcggaa cctgaacatg cttgacatgc atgccaattg
    23821 cagtgtctcc gatatccaat ccagcatgag ccttgataaa ttcaacctca actggatcct
    23881 gcataaactt aaaggctgcc aactgccccg aacctcctgc atgaagagta ggatggacac
    23941 tgacaatttc cagaccaaac tgctctgcca cctgacgttc aacaacgaga gcccgattga
    24001 catgctcaca accttgaact gctaaatgga tacctctact acctagaata cccaagatag
    24061 tctccactat cagctcacca atctcttgac tggattcttt cccaatctga ccacctagca
    24121 cctcactaga agatagacct aaaacaaaaa gggccccctg tttcaaattg gtcttttcta
    24181 aaacatcttc cactacctga cgtgtttctc tttgaatctg tgtctcgttc atctctgtta
    24241 cctctgttgt cactcttcta tcataccgtt ttttcttgtt tttagcaaga tagacaacct
    24301 agaaagtttg cccaattacg cataaaactc ccagaattga ctgggagtta gctagtttct
    24361 attctattta tatatatttc aactttcgtt cctttttggg gtctagaatc aatcttcatc
    24421 tggtaattgg ctccaaaatg aagtttgagc cgttgatcga cattttgaag accaactccc
    24481 ccacgtttga gttgactttg actactatca ccagcatctt ggaagccaac gccatcatcc
    24541 tcaatacgga tgaccaatcc cgaatcctgt ttctggacag aaagtttaat atggccctga
    24601 ccttcctttt ccttaatgcc atggtaaaga gcattttcta caaggggttg taggaccagc
    24661 ttgggtaaga ctaaattatc aaaggcaaca ttttcattaa tttcgtattc cagcttatct
    24721 ccatagcgtt gtttctggat aaagagatac tggcggacat gattgatttc gtcagagaga
    24781 caaatcaagt ccttgccttg attgagcgcc aagcggaaat aggttgccaa ggacttggtc
    24841 acctgcacca ctcgctgact atcatgaaat tcagccatcc agatgatggt gtccaaagtg
    24901 ttatagagga aatgtggatt aatctggctc gaaagggctt gaagttggta ctgacgggtc
    24961 gtttcttcct ggctacgaat agctaccatc aactgatcaa tctgatccaa catggcatta
    25021 aattggcgag ttacttctct cagttcatag gcaccaactt ccttggcacg aagattttga
    25081 gcaccagaag caatttccaa catggtttct ctcaaatcct tcaaaggagc aatccagcgt
    25141 ttaagactga accacactaa gcagagacag acaagaagag atgtgacact agccccaagc
    25201 aaggtccaca agagctgact ccgaacctgg tctaactttt ccaatgatga cacgccaagt
    25261 accgtccaat cagttcctgc aatcttctct tgactgacgt aggatttgtg accaggagta
    25321 taaccctgac ctgtctcgat gtagggtttc atagcctcca ttttgctaga cgaactataa
    25381 actgtgtgtt gaggatggta gacaaattca tggttttcat tgataatgaa ggcaaagccc
    25441 tgctgcccca actggagttg attgagatag gcttccagag tttcataaga aatatccaaa
    25501 cgaagcacac caagattggc tccctttgca tcaacaagtt cttgagtgac agaaatgacc
    25561 cactgactat ctgatttacg agctggagtc aaaacaggca tagctccctg atgaatggcc
    25621 ttttggtacc aatcctcagc catcatatca gaggaagttt tcatctgcac actgtcatct
    25681 gtagaaatga cctgaccaga tttggtcacc agcacaacag ttttcaagtc cttatctgac
    25741 ttcaagatgg tcaaaaacaa atctcggatt ccctcgacct tgtcttgact gggattctca
    25801 gcataggcca gaacatccgt ctgctgggtc aaaccggtcg aagtggtttc tagttttttg
    25861 atataagact gaataaagtg gctagtctgg ctgatggtcg tttggctgtt gccctcaatg
    25921 gtggcctcaa tggctgaaga acttgattga tagtagaaag ttccaaccag agctaggaga
    25981 atgagaaaga ccagaaagat ggaaataacc attctaacta aaagagaaga acgcttcatc
    26041 ggtcttctcc cttcttaaac tgacgaggtg tcacacctgc aatctgctta aaacgttggg
    26101 taaaatagtt catatcttca aaaccaacct tctctgcgat ctcataaatc ttcagatctg
    26161 tagttaaaag caagagcttg gcttgtttaa cacgttctct caccagataa tcctgaaaag
    26221 gcaagcccaa ctctttctta atcaagaaac tcagataggt cggactaaaa cctaagtcac
    26281 tggctaaaga ctttaaacta aattggctat cagccagatg agactggatt ttctgggcca
    26341 tgtttccttc aaacctatta gtcaataaat cttgtaactg ctcttctttc tcttccttgt
    26401 ctagtttttg tttgattttc cccaacattt cctcaatatc ctgacgagaa aagggtttga
    26461 gcaggtagtc gtccacacct agtttgacag cagacaaggc ataatcaaaa tcatcgtaac
    26521 ctgttaaaaa gaccaaatga acctgaggat aggtttctcg taccagactg gccaactgga
    26581 tgccatttag atgaggcatg ttgatatcgg ttaaaatgat atctggcacc tgcttttgga
    26641 tcaattccca agcctgcctt ccattttcag cctgaccgat gatttccata tcgtaggctg
    26701 ctacattgac cagtttagtc aaaccttgtc ttaccagata ttcatcttct acgattaaga
    26761 ttgtgtaggt catgatctgc tcctttacca cttactagta tcagtatagc aaaattctcc
    26821 tctaactgct taggaaagac ctcttatact caataaaaat caaaaagtaa actaggaaga
    26881 tagccacagg tttctcaaag taccgctttg aggttgtaga taaaactgac gaagtcagct
    26941 caaagtatag ctttgaggtt gtagataaaa ctgacggagt cagtaaccct acatacggta
    27001 aggcgacgct gacgtggttt gaagagattt tcgaagagta ttaatcaaca taatctagta
    27061 aataagcgta gcctttttct tccatttggt ctttgggaat aaagcggata gagaggctat
    27121 tgatacagta acgtaagccg cccttgtcct gtggaccatc cgtaaagaca tgcccaaggt
    27181 gagaatctcc tactcggctc cgcacttcca tacgcgtcat attgtaggac ttatcttcct
    27241 tgtaggtgac aacatctgga ctgatgggtt gggtaaaact aggccagcca caaccagact
    27301 caaatttgtc ttttgatgaa aagagaggtt ccccagttgc tatatccaca tagataccgg
    27361 attcaaattt atcccagtaa cggtttgaga aagctcgttc tgtttgattt tcctgggtaa
    27421 ctgcatactc ctcaggtgac agggtctttt tcaattcctc atcacttggt tttggatatt
    27481 tgctggcatc aatgacagga taggccgcct gattaacatt gatatggcag tagccatttg
    27541 gatttttctt gagatagtct tgatggtaat cctcagccac cacaaaattc ttcaagtttt
    27601 ccttttcaac tgctagaggt tgatcgtatt tcttagccac ctcatcaaag acttggttaa
    27661 tcacttccaa atccttgtca tctgtgtaat aaacaccagt acggtactgg gtccccacat
    27721 catttccttg tttatttttg ctggttggat tgataatgcg gaaatagtga agcaggattt
    27781 ccttgagaga aatttgcttg gcatcatagg tgacatggac ggtttctgca tgacctgttt
    27841 ggttaatcaa ttcgtacttg gttgtttctc ctctaccatt tgcatagcct gaaacggcat
    27901 ccgtcacccc gggaacgcgt gagaaatatt cctccactcc ccagaaacaa cctccagcta
    27961 gataaatttc gtgcaagtct gcgtctttac taatttctgt ttttttcact gcttttcctc
    28021 cttggctaac tgccgccttt tcaatttgcg aggcatctgt ctgccctgca tttcgtatca
    28081 atagaacata gaaaccggtt atggctagaa aaaatactcc tagcaacaag aagattttta
    28141 acttatcatt cataagacac ctcctaggct aattccttca aagtttgcaa aattgcatct
    28201 ttttccatga atcctggatg tgttttgacc agcttgcctt ctttgtctat aaaggcttgg
    28261 gttgggtaag aacggacacc ataagtttcc aaaagtttgc ctgatgggtc aactaggact
    28321 gggagatttt tataatccaa tcccttatac caattcttaa agtccgcttc agattgctct
    28381 cccctatgtc ctggtgacac tactgtcaag accacatagt catcaccagc ttctttagca
    28441 atctcatccg tatctggaag actagccaga cagatggaac accaagaagc ccagaatttg
    28501 agatagactt tcttgccctt gtaatcagat aaacggtagg tcttgccatc tactcccatc
    28561 aattcaaaat cagccacctc tttcccttta gctgcgcttg ttttactagc tgtctgctcc
    28621 gtcttcattt catctttcgt ttggtgttca ctagtcacgg acttgcctga acaagccgtc
    28681 aaacaaagga gcgaacctgc tccaagaaca catgtttgcc attttttcat attgatattc
    28741 ctttccattt tattcaaata attgacttaa aattgaagca tttccaaaca gaaccaagag
    28801 tcccatcaca ataatgagaa aaccacccac ttttttgagg attccgagat agggatgaag
    28861 ttttcggaaa tgtttcaaaa cataactaga ggtcagagct agaagcaaga atggtagcgc
    28921 caagcccagc gtatacacca acatgagacc agctccctgc caagctcctg aaccacctga
    28981 agccgccaag gccaaaacag accccagaac cggccccacg caaggcgtcc aagcaaaact
    29041 aaaggtcaag cccaataaaa atgcctgact atagccctta ccattttgcc cctgtccttg
    29101 cagttgtagc ctcttttcct tataaagccc cttaaagtgt agaatctcca tttggtgcaa
    29161 accaagaagg ataataattg ccccagtaaa atattggaac caagaagcat aaagcaaatc
    29221 gcctaaaaaa ccagctccat agcccaacaa aataaatata aaggaaattc ctgctataaa
    29281 ggccagagtt cgtaataaac tagtaactga gattgaaaat ttgccgctag aagcctgagc
    29341 accatcctta tcatctagta acactcctgt atagaccggt aacaaaggta agatacaagg
    29401 agaaaagaag gatagaatcc ctgccaaaaa gacacttaga aaaaagaaaa tatgacccat
    29461 aaagttcctc ctatcatttt attgatagat ttattatact ccttccattt tcgaaaaaac
    29521 agggacaatg ataggggaaa ataggaattt aatcagatga tttagaaatc ttggacaaaa
    29581 actatacaaa aaactgtcaa agcgcaaaag cgcatagtat caaggttcta taaagtcttg
    29641 atactatgcg cttttataat ggataaatag ttagtctttt ttaaagaccg gatctttcaa
    29701 actctgcata ctggcattga tcaccgcgcc taggataaca attttagcaa tcaagataaa
    29761 ccaaaacatc ataacaacaa gaagaacgga acctaaaatt cggacatcca ccaaatgatg
    29821 gacatagtaa ttgagataac tagagaacag agttagtaaa cctaaaatca ctaagagaac
    29881 aaaggcactg cctggtaggg tatagctaat tttcctgtta gatagattgg gaagaaaata
    29941 ataaagcatg accaagatag caaagaggag ggcgtaaatc agaggacctg ccaacccttg
    30001 taaagcctga tagataatgc catcttttgt ccaataatga gcaagtaaag ccaaaatcat
    30061 ctgaccaaat aagatcaaaa acaaggcaaa cgcaaagagg agctgcaagc caaaactgac
    30121 taggagactt agcatctgat gggaaataag tccacgactc ttttcgacgc cataagcctt
    30181 gttaaaagct ttttgcaaga aattcataga ttttgaaaaa ctccataacg ccgataaaac
    30241 agaaaaactc aataaacctg ttgaaggttg cgtcaagact tctctggcta ttttttccac
    30301 accttcatag aggcttgggg gcaggacgtc tttcataaag cccaaaaatt ctcccacagg
    30361 aatctgaaaa taggggagga tattgaccac caccaaaagc agggggaaaa tcgaaatcaa
    30421 ccaatagtag gctactgcga cactggtcaa ctcactatct gatgcttgat aataatgcaa
    30481 aaaagctttt aataaaggct tgtctatcag ctctttccac cactttttca tgtcatactc
    30541 cttcatttat aatcttatac tcaatgaaaa tcaaagagca aactagaaag ctagccgcaa
    30601 gctgctcaaa acactgtttt gaggttgtag ataagactga cgaagtcagt cacatacata
    30661 cggtaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtattaac taatttcttc
    30721 ttaccaattc caccatatca tacggcaggg tattggcagc ttccttcaag gaatagttct
    30781 ctaagttatt tacattttgt cgtaatttct tggcatactt agttgtaatc aatcgttttt
    30841 cttcgtattc gaaaatcaac ttgcgctcca gataatagcc tcttagcatt tcatcgatat
    30901 tgttgggttt gacacgattg ataacccgtt cgacaaaggc accactgctg ataatagctg
    30961 tttctcgaag acgagactcc tgcataaaac taatcaaaga gcgtctgtag actcccttca
    31021 ggttttccaa actttcaata atcatctctg tattggcaag atagagctct gcaatttggt
    31081 cataatcaag agcacggaga cggctttgct ccttgttctt ccagctacgg aaggtctttc
    31141 cgagagtaaa aacttcatga aggagaaaac gtaaaatcct caaggaaaca agaaaataat
    31201 aggtcagtct tgaggcaagt ttacgattga ttccttgttc tatatttttc agataacgtt
    31261 ggtaaactcg gtaagcacga ttgctaatgt tcccctcttc ataggcctgt tccaaaccat
    31321 cactttcaat actaagaatc aagagtttca aagcagccca gtcttcttga tcatcctggt
    31381 tttcttggct taaaatgaga ttttcaatac gtccatgata attgtcaata gccgcataaa
    31441 gggaaagttt atttctggtg tcttccaact ctttttccaa ctctagcgtt acttcattca
    31501 aaatggcgat atgcatgaga taatccttgc tttcttcctc ttcatcagaa agatgaggca
    31561 agaccaagag acctgttaaa aagctaacaa gcgtcacacc tgcaacaagg aaaagcaaga
    31621 gaggatactc ctgttctaga ttacttggta tcaagagaat cgtagcaatc gacaccgttc
    31681 ccttaacacc tgaaaaggtc aagagaaaca tgtccttcat atacttattt agctttttct
    31741 tgaggcgtcg ggttctatag gcataatagc catagatcat aataaaacga atgacaaaga
    31801 ggacaaaggt aagggcgata agagatagca ataaaagtag aggattatag attggattgg
    31861 tcaagatagg ttctgctatc atttccagct ccatccctaa aatcacaaag acagaaccgt
    31921 tgagcataaa ggtcactgta tgccagaccg tctcggtcac cgtatccact tgggcttcga
    31981 ggagcgtgat tttcttgaag cgacttgcct ttaaaattcc agcaactacg acggcaataa
    32041 tacctgaaac atggacttct tctgccagaa agaaggtcac tagaggcaaa ctcaattcta
    32101 ataaaagttc actggcaata tccgttgcgc gcacacttag caagaaggta tggaggaagc
    32161 ggttggtcat ggctgttaaa aatccaatta aaaaaccgcc taggattgaa aagatgagcg
    32221 aactgctagc ttgccccaga gaaaaagctc cagttgtcca agctgtcaaa gctacctgaa
    32281 aagccaccaa accagaagca tcattcaaga gtccttcgcc cttaagaata ttggacacgc
    32341 gcttaggaaa gctaaaacgc tccgaaagag aggcaaaggc caccaagtcc gtaggaccaa
    32401 gggctgcccc aacagccaag caagctgcca agggaaggct gaaccaaaga agatgggcca
    32461 agccacccaa actcagggtc gagataaaaa tcactggaaa tatgagataa acaatgattc
    32521 gccagtgttt taaaatagcc gtaacatctg cttcttcagc ctctcggaaa agcaagggtc
    32581 cgataaccag tgccaaaaac aactccgtat taaggtgaaa gtcagtattg ggtaaaaaga
    32641 gaccaatcac aattcccaaa agaatctgca ccaaagggag aggcaaaaag ggcaggagct
    32701 tattggttgt acttgagaca atcaaaacca gtaaaaatag gatgaggtaa atcagtaatt
    32761 ccacgcacgt cctccttaat cttttttaca acaggattca aatatctcct tctgatcttt
    32821 gattttttgg tcaatcttgg aacagtcttt gtgctcaatt tttctctggc accgttccat
    32881 ttcaagagca actaattttt tcttgatttt aagcattttt ttgctcatat gtgcttggtc
    32941 tagcacgccc accgatcgtt cgtggtgggt tgattcaaca aaattctggc gcatggcatc
    33001 cagcttttcg tgtaggtatt gtttatccat gtctgtatct ctctaatttt tcaatcatca
    33061 ctaaaaacgg cgggttgttg acttggttta aagttcggta aatggcagct gtgtactctt
    33121 gttggttcaa ctggattaca aaatccaaga cagcatctct ctcgaggtcg cctccttcat
    33181 gaccatagta aatcataata gcaattcgtc cacctttgac aagtaagcca catagctttc
    33241 ctaatgcctc aatcgttgtc tgcggtcggg tgatgataga cttatcagct gacggcaaat
    33301 agcccagatt aaaaatccct gccttagctt ttgtcacaaa ctggtccagt gtctcatggc
    33361 cttgcaagat taactgggca tttgtcaagc cagcctgatg caaacgctct tgggtctttt
    33421 tcaaggcttg cttctgaata tcaaaggcat agacttgctt ggctagcttg gctaaaaaaa
    33481 gcgtgtcatg accatttccc atagtcgcat ccactacgac atcctctttt gtcacgacct
    33541 cagccaaaaa atcatgtgcc atctcaagtg gtcttttcat tttcaaactc ctgttttaca
    33601 gccttgcatc cttgaacact tccacgacgt cgcatctcca tctcaatgct gttgagagct
    33661 tcccatttat tgaggctcca cataagccca atcagcatat ccctaggtgc atctcctgtg
    33721 attcgatgga tgacgatatg tttgggaata atttccagtt ggtcacagat gaccctgaca
    33781 tattcgtcct gactcatcaa ttgtaaacgt ccctcatggt aatctcgttg catacgagta
    33841 tttgtcataa gatggagcaa atgcagttta atcccttgaa tatcgttatt cgtgacacaa
    33901 cggcggacat tttcaaccat catctcatag gtttcaccag gcaaaccatt gatcaaatgg
    33961 gaaacaatct caatttttgg atactttctc aaacgcttga ccgtttccac ctacaattca
    34021 taagaatacg cacggttaat caggtcagaa gttgcttcat aagtagtcta caagcccaat
    34081 tcaaccgtca catgcatgca ctccgataac tcagccaaat attcgatggt ttcgtctggt
    34141 aaacagtctg ggcgcattcc aatattgatt cctaccacac ccggctcatt gatagcctgt
    34201 tcataacgct ctcgaataac ttccaccttt tcatgggtgt tggtaaaatt ttgaaaataa
    34261 accagatact tctgaacatc cggccactta cggtgcataa agtcaatttc cttataaaat
    34321 tgctcacgga taggcgcatc tggggctaca atagcatctc cagaacctga aaccgtacaa
    34381 aaagtacagc ctccatgagc cacagttcca tcacgattgg gacagtcaaa ttccgcatca
    34441 atagggactt taaaagtctt ttctccaaag agttttcgat aataatcatt caaggtatta
    34501 taagatttta taactttcat tataacaaaa atcacccaca atctcaaaag cctgactttc
    34561 ctataaattc ctctgtttct cgtttccatt agcttttttt tatgatacaa tatgggtatg
    34621 attttaatga aattagcatc tattttatta ttgatactga ccttagtcgt ctgcattatc
    34681 ctaaccaaac tttttagatt aaaaaaacta ggacgaaact ttgcggattt ggcttttccg
    34741 gtcttggtat ttgaatatta cctgattaca gctaaaacct ttacccataa tttcctccct
    34801 agactggggc tagccctctc aatcctagcc attattctcg tctttttctt ccttttgaaa
    34861 aaacgcagct tttactatcc taaattcatc aaattcttct ggcgtgcagg attcttatta
    34921 acccttatca tgtatataga aatgattgtt gaattgttct taatgaaata gtcgaatccc
    34981 taagcatttt ctagggattt ttgctttctc tgcaaaatag tatagacaat aacactatac
    35041 aattttatac aaagaaaaga gtctgggaca atagtctctt atctccaaaa aaagcaacgg
    35101 atttgccgtt gctttttttg catggttacg atagtcttgg taaaatagaa ttgcccaata
    35161 aaccatttag aaaggctatc ccatgcatat tcactataac acaaatcaaa caactttacc
    35221 actagaaatc agttccttct taccacaaga ccatctcgtc tttactattg aaaaagtggt
    35281 gaataccttg gaggaacatc acttctacgc cttctatcat gcctttggtc gcccgtctta
    35341 tcaccctaaa atgcttgtat ctactcttct atttgcctat tcacaaggga ttttctctgg
    35401 tcgaaaaatt gaaaaatgga agagttagtg accttagatt gtttgtttat tgacggaact
    35461 aagattgaag ccaatgccaa caagtatagt tttgtgtgga agaaaacgac agagaaattc
    35521 tccgccaaac ttcaagaaca gatacaagtc tattttcaag aagaaatcac tccccttctg
    35581 attaaatatg ccatgtttga taagaaacaa aagagagggt ataaagagtc agctaaaaac
    35641 ttagcgaatt ggcactataa tgacaaggag gatagctaca tacatcctga tggctggtgc
    35701 tatcgttttc accatatcaa gcaccagaaa acacagacag actttcaaca ggaaatcaag
    35761 gtttactacg ccgacgaacc tgaatcagcc cctcaaaagg ggactgtata tgaacgaacg
    35821 ctatcaaaac ttgaaagcta aagaatgtca ggcgctttta tctccccaag gtagacagat
    35881 tttcgctcaa cgcaagattg atgtggaacc tgtctttggg cagataaagg cttgtttggg
    35941 ttacaagaga tgtaatctga ggggcaagcg tcaagtgaga attgacatgg gattggtact
    36001 tatggccaat aacctcctaa aatatagtaa aatgaaataa gaacaggaca aatcgataag
    36061 gacagtcaaa tcgatttcta acaatgtttt agaagtaaaa gtgtactatt ctagtttcaa
    36121 tccactatac aataagagaa tgactcaaaa ttaaaaagct agagttccac aattggaaat
    36181 atctagcttt tttgtggttg agaactattt tgtcccagac tctttatctt ctatttagga
    36241 caagagtttt tctttggtct ttaatgataa agaaggtatc aaaatttcta gtcttctttt
    36301 ttacctttag taactactaa tcctgcactc aaacctagaa gagctaaacc tgctgctact
    36361 gctgcttggc ttgccgcact acctgtattt ggtaactggg ctttattagt ttgactagct
    36421 tcacttgaat caattggttt tgtatctgct ttttctgaca cttgtggttt tttagcttct
    36481 tgagctactg gtttggttcc aaccaagacg atgcggtctg tcggagcttc taccacttca
    36541 cggagttttt cttccttact tccatcagga ttaatcgctg taaagatacg ttctttacca
    36601 gtttttcctt cttgttctac acgagtttca cctagataca gtgttgaatc ttttttctca
    36661 actgtcttgt atgccaaatc tttttcaaca aattcgagtt ttggaagatc ttcttgtaca
    36721 gcagcaactg tcttctcaga aactggtttt tccttagtca agtggatacg gtattccttg
    36781 acttgttttc cactttctga aacgaggcga acaagtactg gaaggctatc ttctccacta
    36841 tctaccacag ttgaagctac ttgattattt tcttcaactg agacttttgg ccgttgacct
    36901 ttataggtga tttggtagtc ttgacgattt tcagcgaaat cagcaagttc ttttccatct
    36961 acaagaatct tcgattgcgt actttcttga ggcaattcac ttggtgcaag gaaggtcatc
    37021 tcaatcatcg caacaccgct cttatctgct ttacgctcca tacgccatct catagctttg
    37081 gctttgacag ctttaaatgt tacgttgatt tcatcaccag ctgcgatgtc tttatccgca
    37141 cgataaggca cagcttccca attttctgga ttgttgaatg gatggtctgc gtcgtaggct
    37201 tggtagtttg aatagtaggt tggcacttca aactctggac cgacatagcg ttctaaaacg
    37261 agtttagttg gtgcatccgt accactatct gcaaagaagt gaagtttggc ttgagcaaca
    37321 gtccgttcta caatcttacc attttcacgg aagatcacac ccgctgatac ttctggatta
    37381 gaagatggtg ttggagacca gtttgtccaa cgacgatttt ctgaatgatc tccgtcattg
    37441 agatagtcaa cgcggtcatg agagtttttg tcaatatcat tggttgctga agcaaaggcc
    37501 tggttactgt tttcatcata gttagggtta tctgaaagag cctcaccaag tttgtctgtc
    37561 actcgtacag tgacctcagc aacaaggtca ctaccaagga cacggcctcg aatagtaaat
    37621 tgacctgctt ttgtcagatt ttccgctgga acttcttccc attcaactgt caggtctttt
    37681 gtttcgtagc tgtctttacc tgtgaagtaa actggaacct tagtcggcaa ttcaagtgct
    37741 tgacctactt gtagcaagcg agcttgttta accgcagcaa ctggtttatg agaaagtaag
    37801 ttcttatcct tagtgaagtg cagacggtat tctcctaaga tatcgccatt ttcagctttc
    37861 gcgatgacac gaactggctc accttcacga acgcttggaa cgacggtagc gagaccattg
    37921 ttgctaacac ttgctgtgac tgccggaact tttccatcta cagactcaag gtagtagtct
    37981 gtcaaatcag ggttgaagtt tgctaagtct ttgccgtcaa cttggattct tgtttgtcct
    38041 tgcttggctg ccgcaacttg tttcgcaaag atttgtacct ctgtgataga cgttccacgc
    38101 ttgttatctg ctttaaccat gcgaatacga atagcatagg tttcaacttt atcaaagcta
    38161 aagtggttca tttctccagc cttgagttga gcaggggctt ttagattagt aactggtttc
    38221 cagttggcag aatcattaaa gacatggtcc tcattaccaa caaaactagg gtttttagga
    38281 gctgttggga cagtcttacc aacataatac tcaatcacat aagacttcgg tgcaccaact
    38341 ccatggtctt cgtggaatcc gacacttaga ttatcaacgg agcgtttgct caagatacct
    38401 gaatctccaa acagaacacc gactgaagct tctggattac tacgattcca gtttgtccaa
    38461 cgattggctg gttggttatt gtaggaaatg agcttgtcat taacatttga aactgggtcg
    38521 cttggatttg aatctgaagc aaaggcaagt ggcaattctg aaccggtcca ttggtcagaa
    38581 atgtttgcac cttgctcagt ttgagcagat acgcgaacat gaagtttagt tgttaattgc
    38641 gtaccttcta agcgaccatt aactgtaaag acaccttcct tagcgtattg ctctggacga
    38701 atcgcatccc atgcaacctt agctgatgaa acgtgaccat ttgaatcata tgtccgaacg
    38761 ctttctggta attgtggtgc ttctgcgatt ggagttgtca cactgacttc ttcaactgaa
    38821 acgatacctt ctacagagac ttttgcacgc gcttcaaggt caattccttc aactttacct
    38881 agtacttcaa atgtttgata ggagtctagt ttttctttcg gaatagcttg ccaagtgact
    38941 ttatgagttt tagggaaacc tttgtcatac tcaactgtta ctgttgctgg aagacttggt
    39001 tcctgatgca aatctgtcac tacatttaca ggacggatgg attgcgcaat cttcttctca
    39061 gtattggctt ggatagtgag ttcaacttgg cctttagctc cctcatattc agcgttcaga
    39121 gtgactgctc ctggcttatg caactcaagc attcctttac gaattgcgac ttccccttca
    39181 ccacttgtag agaaggttac tttatcagct ggtaatacag cttgcgttcc atcttgatag
    39241 tgagctcgaa ccgacaattt gacagtttgg tcttctttga gactgtcagc tttttccact
    39301 tgcaagctca agtgagcaat ttttggtgct tcttctagga attgaattgc ataggtttga
    39361 agagggccac catctttagg ctgaacaaat atgcttgcac gcatgccgtt tgctgcgctt
    39421 gcttgaagaa ctgtcacatc agcattttca gcacttgctg tgacttctgg caattgggca
    39481 ccataagata gagtacgata ttgcattggt tgtcgactag taagacctgt tactgcttca
    39541 cctccaacag taacagttgg cactacaggt gctgcagcat ttccttcttc taccacaagg
    39601 gttgcatgaa tagtttctcc agctaactga ccagtcattt gaatacgtga tccagctact
    39661 gaaagtttgg ctttatctac ttccgtaatc tcccagctat ctacttcgta ctcttgtaca
    39721 cttccatcag tcaaaacata agaaacagat ttgtctacag aattcaagtc agtatttgga
    39781 gcaatacatt taactgttgg taattctttc gcaattgcta gaacctcgac atgagcctct
    39841 acctcacgtc catttgctgt acctttaaca gtcacaactc ctgcttgact aacatcgact
    39901 tgagaccaag ttactggaag tttttcacga ctaccatcgc tgtatacaaa acctactgtt
    39961 ttcggcattt ttggttcttt accaattaat gtacgaactc ttgctacttc tgtccccaaa
    40021 acagtcttct cttgtccttc tttcttacca gtaaagacag tgacttggtt cgatttcaag
    40081 agatcagagt gggcagtaag ggtgaatttc cctgcttgtt cagttgattt gacaatggca
    40141 acacctttac cattaaatgc tttacgaatc caagaaccat ctgcttgcgc cttatagcgt
    40201 tcacggctgg cttgttctcc gttatctaca ccgaccagtt gaccttggcc atgcaattgg
    40261 aagcgaacca gattattagc agttggaacc acattcccct ggctgtcaac aatttcatag
    40321 tagatgtaag tcaagtcttt tccatctgct gcaatcgcat ggtcttcctt aataagacga
    40381 actgccgctg gcttaccagc agtcgtaatc ttatctcgag caatttcctt gccagattca
    40441 tcacgagcaa ttgcttccaa ggtacctggt tgataggcaa ctttccattc aagataaagt
    40501 tcattagcat ttgcaccttc ttggtaagtc cgcccatcgc tggtttgttt tttattgaaa
    40561 gtcttaagac caagagattt tccattcaag aacaattcta cactagaagc attcgaataa
    40621 gcacgaactg gaatcttacc ttctgagtca gctactttgg atgctaattc tttgttttcc
    40681 cagttccagt gaggaagaag gtgtaccatc ggtttcttct taacagaaac ccattggctt
    40741 tggtagagat agaagtcatg ttttggaatg ccggctgtat ctacgatacc aaagtaagag
    40801 ctcttaacag gagtttgatt ttggttgtgc catggtgtag gttcaccaat atagtccgta
    40861 cctgtccaga taaactgtcc agcatagcca gcgttgtcac ggtcaaaagt ccatgaagcg
    40921 gttgctgttt tcccccaacc cacacgatca tttccataat ctgactgttc ataattacgc
    40981 tcaggtccat tgctatgttt caattcacgt tcagggcgat agtaacttcc acgtgtacgg
    41041 gttgctgatg atgtttctga accgtaaatc aaccattttg gatgcttagc tctaagggct
    41101 ttgtaattat cttcagaata gttaaatcca acagcatcga gttcatcagc aattttctca
    41161 tgccctccgc taccattgcc gaaacggaat ttatctgctc ccatggtaac atagcgagtc
    41221 ttatcaacat ccttgataac cttgaccaaa cgtttaacag ttgctaaaga gtgggcatca
    41281 ccattagctt cacctatttc attaccaatt gaccacatga agatagcagg gttgtttttg
    41341 cctctttcga ccatggtacg taggtcaaaa tcagaccatt tttcaccttt tcgagcttct
    41401 gggtgagtgg catctttttc aaagaaacgt ccatagtcat aaggtttctt gccaccatac
    41461 cacgtatcaa aggcctcttc ctgaacgagt aaacctagtt ctgctgcgat ttgcaaggtt
    41521 tgctcactag cagggttgtg ggttgtacgg atagagttaa ctcccatctc cttcatttgt
    41581 ttgagacggc gatattctgc tttatagttt tcttctgctc caagcgcccc atggtcgtgg
    41641 tgcaaggata ctccatggaa tttaatacgt tcaccattca aagagaaacc ttcatttgga
    41701 gtccagtgat agtaacggta accaaacaaa tccttcttag catcaaccaa ttgaccgtca
    41761 cggtaaacac gcgtaatcaa ttcgtacaag gcaggtttgt catttaaaac ggtccagagt
    41821 tttggtcttt caacttctaa aatcgcatct aggcttgttg attcatgtgc ttttaaggta
    41881 cgactcgctg tacgaactaa gcctgttaca gcatgaccac ctcgttcaac gatttgatat
    41941 tcggctacaa gttcatggtc tttgtcgtcc gtattgacga ttttgctggt cacatgagtt
    42001 tcaaccttgc catgttgttg ttcttcaagt tttggtgtta aaatagttgt cccatttttc
    42061 tcaacatgca ccttatctgt cacttgtaaa gtcacatcac gatagatacc acttcctgaa
    42121 taccaacggc tacttggctg tttgttgact gcatggacag caatcacatt ctcacgacca
    42181 tctttgtgaa ggtatttggt gatatcgtat gagaactggt tataaccatt tggataatgc
    42241 cccactaact gaccattgac ataaacttga gaatccatgt agacgccatc aaaagtaagg
    42301 cgaacatttt tcttgaggtc tttttcatct agtttgaaag tcttgcgata ccaagcttcc
    42361 ccaccgttga gctgtccacc ttcattttgt gcaggagatt catgatcgaa atcgttaaag
    42421 atactccagt catacggtaa atctaatttt ttccacgtag atacgtctgc atcaggttta
    42481 atggcttcct tagaatttgc attgagttta aagtaccaat tttgattaaa atccactttc
    42541 ctgtcttcaa tcatttgatt cacttcttca tttgttacag ctttagcatc ttccttgagc
    42601 ggtttttctt gacttgaagc ttgtgattct atccttggag ctttttcttc cggtttagca
    42661 gacacttttt cctcttttgg agttacggct tcatcttctt tcttctcaga tgcaatagcc
    42721 tcagttgaac taggttcact ttgttctgtc ctttcaacta catttttagt ttccaaagct
    42781 ttatcagcct tttcttctac tatcattttt tcctctttag gtttctcagc agtatgagta
    42841 ataagtgttt catccgcata aactacagat tctccagcta tatttcctcc taatagaact
    42901 gcacaagtcc caatcattac tgagcaagct cccacagcaa acttacgaat gctataaact
    42961 cttttccgat tccaatggcc tttccccata aaaccctcct tatattatat ttagtgcagt
    43021 tagctactac caaagcccaa gtggtataca tggtatgaca acctagtttc aacaatttac
    43081 actctgcgaa aatccaattc aaacttcgtc agtgtcgcct tgccgtagat atgatt
//
LOCUS       DAVKXA010000013        41852 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKXA010000013 DAVKXA010000000
VERSION     DAVKXA010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.013"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(116..1750)
                     /locus_tag="VW883_000750"
     CDS             complement(116..1750)
                     /locus_tag="VW883_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273925.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIALTVFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENLDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVKRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1731..2480)
                     /locus_tag="VW883_000751"
                     /pseudo
     CDS             complement(1731..2480)
                     /locus_tag="VW883_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            2659..4113
                     /locus_tag="VW883_000752"
     CDS             2659..4113
                     /locus_tag="VW883_000752"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0273926.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4203..6821)
                     /gene="alaS"
                     /locus_tag="VW883_000753"
     CDS             complement(4203..6821)
                     /gene="alaS"
                     /locus_tag="VW883_000753"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0273927.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(6843..7328)
                     /locus_tag="VW883_000754"
     CDS             complement(6843..7328)
                     /locus_tag="VW883_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0273928.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7603..7842)
                     /locus_tag="VW883_000755"
     CDS             complement(7603..7842)
                     /locus_tag="VW883_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273929.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8103..9173)
                     /locus_tag="VW883_000756"
     CDS             complement(8103..9173)
                     /locus_tag="VW883_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0273930.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9170..9943)
                     /locus_tag="VW883_000757"
     CDS             complement(9170..9943)
                     /locus_tag="VW883_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0273931.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9940..10746)
                     /locus_tag="VW883_000758"
     CDS             complement(9940..10746)
                     /locus_tag="VW883_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0273932.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10727..11884)
                     /locus_tag="VW883_000759"
     CDS             complement(10727..11884)
                     /locus_tag="VW883_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273933.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(11943..12893)
                     /gene="murB"
                     /locus_tag="VW883_000760"
     CDS             complement(11943..12893)
                     /gene="murB"
                     /locus_tag="VW883_000760"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0273934.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(13005..13757)
                     /locus_tag="VW883_000761"
     CDS             complement(13005..13757)
                     /locus_tag="VW883_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0273935.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13767..14498)
                     /gene="budA"
                     /locus_tag="VW883_000762"
     CDS             complement(13767..14498)
                     /gene="budA"
                     /locus_tag="VW883_000762"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0273936.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14640..15911
                     /locus_tag="VW883_000763"
     CDS             14640..15911
                     /locus_tag="VW883_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0273937.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(15931..16746)
                     /locus_tag="VW883_000764"
     CDS             complement(15931..16746)
                     /locus_tag="VW883_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0273938.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQVGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
     gene            complement(16903..17556)
                     /gene="phoU"
                     /locus_tag="VW883_000765"
     CDS             complement(16903..17556)
                     /gene="phoU"
                     /locus_tag="VW883_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0273939.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17568..18326)
                     /gene="pstB"
                     /locus_tag="VW883_000766"
     CDS             complement(17568..18326)
                     /gene="pstB"
                     /locus_tag="VW883_000766"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0273940.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(18339..19142)
                     /gene="pstB"
                     /locus_tag="VW883_000767"
     CDS             complement(18339..19142)
                     /gene="pstB"
                     /locus_tag="VW883_000767"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0273941.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19153..20037)
                     /gene="pstA"
                     /locus_tag="VW883_000768"
     CDS             complement(19153..20037)
                     /gene="pstA"
                     /locus_tag="VW883_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0273942.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20027..20944)
                     /gene="pstC"
                     /locus_tag="VW883_000769"
     CDS             complement(20027..20944)
                     /gene="pstC"
                     /locus_tag="VW883_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0273943.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(20944..21822)
                     /gene="pstS"
                     /locus_tag="VW883_000770"
     CDS             complement(20944..21822)
                     /gene="pstS"
                     /locus_tag="VW883_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0273944.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22396..23700)
                     /locus_tag="VW883_000771"
     CDS             complement(22396..23700)
                     /locus_tag="VW883_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0273945.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDVMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23701..24474)
                     /locus_tag="VW883_000772"
     CDS             complement(23701..24474)
                     /locus_tag="VW883_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0273946.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24464..24742)
                     /locus_tag="VW883_000773"
     CDS             complement(24464..24742)
                     /locus_tag="VW883_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0273947.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24742..25143)
                     /locus_tag="VW883_000774"
     CDS             complement(24742..25143)
                     /locus_tag="VW883_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0273948.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25353..25970)
                     /locus_tag="VW883_000775"
     CDS             complement(25353..25970)
                     /locus_tag="VW883_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0273949.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(25960..26733)
                     /locus_tag="VW883_000776"
     CDS             complement(25960..26733)
                     /locus_tag="VW883_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0273950.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26744..27481)
                     /locus_tag="VW883_000777"
     CDS             complement(26744..27481)
                     /locus_tag="VW883_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0273951.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(27486..28616)
                     /locus_tag="VW883_000778"
     CDS             complement(27486..28616)
                     /locus_tag="VW883_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0273952.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28700..29089)
                     /locus_tag="VW883_000779"
     CDS             complement(28700..29089)
                     /locus_tag="VW883_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0273953.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            complement(29105..29488)
                     /locus_tag="VW883_000780"
     CDS             complement(29105..29488)
                     /locus_tag="VW883_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0273954.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29489..30277)
                     /locus_tag="VW883_000781"
     CDS             complement(29489..30277)
                     /locus_tag="VW883_000781"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0273955.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(30270..31205)
                     /locus_tag="VW883_000782"
     CDS             complement(30270..31205)
                     /locus_tag="VW883_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0273956.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31335..31511)
                     /locus_tag="VW883_000783"
     CDS             complement(31335..31511)
                     /locus_tag="VW883_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0273957.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31651..32358)
                     /locus_tag="VW883_000784"
     CDS             complement(31651..32358)
                     /locus_tag="VW883_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0273958.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32509..33537
                     /gene="queA"
                     /locus_tag="VW883_000785"
     CDS             32509..33537
                     /gene="queA"
                     /locus_tag="VW883_000785"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0273959.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGSHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQRIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34086..35213)
                     /locus_tag="VW883_000786"
     CDS             complement(34086..35213)
                     /locus_tag="VW883_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0273960.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGSIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEKVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFTTKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(35929..36480)
                     /locus_tag="VW883_000787"
     CDS             complement(35929..36480)
                     /locus_tag="VW883_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0273961.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(36727..37551)
                     /gene="nadE"
                     /locus_tag="VW883_000788"
     CDS             complement(36727..37551)
                     /gene="nadE"
                     /locus_tag="VW883_000788"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0273962.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(37548..39008)
                     /locus_tag="VW883_000789"
     CDS             complement(37548..39008)
                     /locus_tag="VW883_000789"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0273963.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(39124..39612)
                     /locus_tag="VW883_000790"
     CDS             complement(39124..39612)
                     /locus_tag="VW883_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273964.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(39602..39811)
                     /locus_tag="VW883_000791"
     CDS             complement(39602..39811)
                     /locus_tag="VW883_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0273965.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(40196..40921)
                     /locus_tag="VW883_000792"
     CDS             complement(40196..40921)
                     /locus_tag="VW883_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0273966.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQY
                     LVLITTIILLYFFTLKKSKKYSF"
     gene            complement(40937..41728)
                     /locus_tag="VW883_000793"
     CDS             complement(40937..41728)
                     /locus_tag="VW883_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0273967.1"
                     /translation="MNFALNKGEIVGLAGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQEIFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLSITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        12581 a         9434 c         7794 g        12043 t
ORIGIN      
        1 tcaaaacatt cctccctata tttttgatta ccaatcttaa tcatttacaa ctacattcta
       61 acaaactata aaagcgtttg tcgaattgaa tttatcaagc aagcaaccaa ctatctcatc
      121 ttttttctat ttctgccaat atgcgtgaca ggtaataatg atagccaaaa atagcaagag
      181 caagcaagac gataagagct cctactccca agttgatggc aaggataggg gagagagact
      241 gaaccaagaa tatgctccca attacaaggg ccatcaggat tgcactataa ataaacaata
      301 aaactatggc gactatgcca tttgaacgct tcaccaggtc cgtaatgcta ctccaattgg
      361 ttgacagatt tttaacgtcc ttaaagtaat ggtggcaaga aaggatgaca ctggcaatga
      421 tccagactac aagaaggtaa atcatcgaaa ggatggacaa gcctagatat agagaaagac
      481 cgagcaaagt cagaattggt aaaaaggact gaacagcata gataatccaa aatttcactt
      541 tcacataacg agcaaagtca aagggtaaac tcttcagaaa atcaagattt tccctctcca
      601 aggacaaggc aattgaatgc aggctggtga tattgttatt gacaactgct ataaacactc
      661 ctacaaaaaa caagggtaac cagtatggag gatgaatgtc tggaactatc tgagaatctc
      721 ggattttgga aatcagactg atcatcatga gataaggaag gaaagcactt gtaaaaagca
      781 ctgtaatcac gccagtcccc tgtcccaaga gggtgaggtg gtagcgtaaa accatacgga
      841 aaaagccctt tttagtagtt gaaatcctct ccttgctgcg acgttctttt ttgaccttct
      901 cctcactgtt aagcaggatc acgtcataaa aacgaggaag gaccttcttt ttggtcaggt
      961 aaagcaagaa aacagttaaa gctatccaag cgagcagacc caatatggct tctattgaaa
     1021 aaggctccac tgctattttg taaaagatat gaagaggata aaggagaaat ggaatgtctc
     1081 taactttgtc aacaatactt ccaaaagtcg actgtagaaa gaagacaaat attaaaggta
     1141 tgagaactcc tatcccaatc atcacattcg aaaaaataga ctgatacttt ctgaagaccg
     1201 tagtttgagc caagaaatgc actgccacta ccatcactag agccacagag acaaataata
     1261 aggtcaagga cagtagcatc aaaggcaaac ccagccatag agaaggagct agcctaatgt
     1321 agaggactag aaaataagct aggattggta caattccagt tagagctggc aaaaggacag
     1381 acagtccttt agcaattata atctctgatt ctttaaaggc atagggccta taggaggcca
     1441 ggtccttact ctcataaaag acattgtaaa aggccgttaa agaagttgaa aaggcaatca
     1501 ctagtaaaat agcaaccatc gagctaaaat aaataggcat ttcctcaaaa ggaaaatgaa
     1561 tggctatatt actaaaacag atgagcatca agagactgga aaaaatgtaa gaacttagga
     1621 ctctagcaga aacatttact tttttcccag gattcttagc ctgcttcttt cgtagattag
     1681 ccagattagc ttcttgagat gaatagagga tattgatatc aactaatttt ttaatgacct
     1741 tgagacgcat ccgcaacctc ctcttttcta ccagcaagac taaggtagat actttccaaa
     1801 aactggtctg ggtggtcttt cctcaagttc tctacactac cacaatagat caaatgcccc
     1861 tttttcaaaa tagcaatccg atcacagact tgctcggcta cctcaaggac atgagttgaa
     1921 aacaagaccg tcttgccttt ttatgcatgt tccttcatca tttgcttcaa atcaaaggcg
     1981 gcctggggat ccaaaccagt caagggttcg tccaaaaccc aaatatcagg agcagacaag
     2041 agtgccccaa tgacaaagac tttctgacgc attccgtgag aaagagtttc aataacctga
     2101 tagcggtttt cagcaaaatc aaaaacgttc aatagcctag ctagactagt ctccaagtca
     2161 gagctagtca gatcatagga tgaagcgatc aattcccaaa attcattggc cgttaagcgt
     2221 aaaaataagt caggcgagtc tgctacgtag ccaatctttc gtttgatcgc caagcgattt
     2281 tccgataact cctgaccgtc taccaaaata cgaccactgc tgggtgaaat gatactgact
     2341 agggatttta tggtggtcga ttttccagcc ccattatgac caatcaagcc cataatctct
     2401 ccattttcaa tctgcaaatt gagattactc aaggcctctt tatcaccata caacttacta
     2461 acattttgaa attcaatcat gggacaactc ctatctttat ctgtattata catcgctata
     2521 ctagcacttt gatacaaaaa aatcaatact ttattttaag tagttaaaat agtttccttc
     2581 tatcttacgc aaacgtttgc gccgagagat actttatgat agaataaaga acaagattga
     2641 caagtaagag gaaacatcat gcaaaatcaa acactcatgc aatactttga atggtatctg
     2701 ccccacgacg gtcaacactg gacgcgtctg gctgaaaatg ctccacacct agctcatctg
     2761 gggatcagtc acgtctggat gccaccagcc ttcaaggcaa ccaacgaaaa agatgtcggc
     2821 tatggggtct atgacttatt tgacttagga gagttcaacc aaaaagggac tgtccgcacc
     2881 aagtatggtt tcaaagaaga ctatcttcaa gccattcaag cccttaaaga acagggaatt
     2941 caacctatgg ccgatgtagt tctcaaccac aaggctgctg ccgataacag ggaagccttt
     3001 caggttatcg aagttgatcc tgtagaccgt acagttgaac ttggagaacc cttcaccatc
     3061 aatggctgga ctagttttac cttcgatggt cgccaagata cctataatgg cttccactgg
     3121 cattggtacc acttcaccgg tacagactac gatgccaaac gcagtaaatc tgggatttat
     3181 ctgatccaag gggacaacaa gggctgggct aacaaggaat tggtcgataa cgaaaacgga
     3241 aactacgact acctcatgta tgccgaccta gactttaaac atcctgaagt catccaaaac
     3301 atctatgact gggctgattg gttcatggaa acgactggtg tagctggttt ccgtttggat
     3361 gccgttaagc atattgactc tttctttatg cgcaacttca tccgcgatat gaaggaaaaa
     3421 tacggtgacg atttctatgt ttttggtgaa ttttggaacc cagacaagga agccaatctg
     3481 gactatctcg aaaaaacgga agaacacttt gaccttgtcg atgttcgtct ccaccagaat
     3541 ctctttgaag ccagtcaagc tggcgcaaac tatgaccttc gtggcatttt cacagatagc
     3601 ctggttgaac tcaagcctga caaggctgtg acttttgtcg acaaccacga tacccaacga
     3661 ggacaagccc ttgagtctac cgttgaagaa tggttcaagc cagcagccta tgccctcatt
     3721 ttgttacgcc aagacggcct tccatgtgtc ttttacggag actactatgg gatttcaggc
     3781 cagtatgctc aagaagattt caaagaaatc cttgaccgcc tcctagccat ccgaaaagac
     3841 ttggcctatg gagaacaaaa tgactacttt gaccatgcta actgtatcgg ttgggtacgt
     3901 tcaggtgctg aaaatcaatc cccaatcgca gtccttatct caaatgacca agaaaacagc
     3961 aagtcaatgt ttgtcggtca agaatggact aatcaaacct ttgtagattt acttggtaac
     4021 caccaaggtc aagttacaat tgatgaggaa ggttatggac aattccctgt ctcagctaga
     4081 tccgtaagtg tctgggcagt caataccatc taatagctca taataaccaa gctaggtcca
     4141 agcggatttg gcttttttgt attcacaaaa agacctaccc aaatggatag atctttactt
     4201 gattacaatt tacctgctac tgcatccaac aattcttgga tcttagcttg gttgcttcct
     4261 cctgccatgg ccatgtctgg tttaccacca ccacgtccat cgatgattgg tgctaattct
     4321 ttgacaaggt ttcctgcatg aaggtctttt gtcttgcttg ctacaaggac attgactttg
     4381 tcaccgatag cggcaactag gacaagaaga tcagagtagt ctttttgttt ccagttatct
     4441 gcaaaagtac gaagggcacc ggcatcggat acagacactt gactagcaat gtaacgatga
     4501 ccgttgactt ccttaacatc tttgaagata tcgcctgcgg ctgcagctgc ggctttttct
     4561 ttcaactcag cattttcttt ttgaagttga cgaagttgtt cttgaagtcc ttctaccttg
     4621 tgaggtactt ccttgacttg aggtgctttc aaggttgctg cgatagcttt aagagcatcc
     4681 tcttgttcac gataggcttc aaaggcttcc ttaccagtca ctgccaagat acggcgagtt
     4741 cctgaaccga ttccttcttc tttgacaatt ttgaagagac caatctcaga agtgttgtca
     4801 acatgagtac caccacaaag ttcaatagag tagtcaccga tagtcacgac acgaacttcc
     4861 ttgccgtatt tctcaccaaa gagggccata gctcccattt ctttagcagt gtcaatatcc
     4921 gtttcaactg tcttcacttc aagtgcttcc caaattttct cgttaacttg ctgttcaatc
     4981 gcacgaagtt cctcagcagt tactgcttgg aagtgggtaa agtcaaagcg aaggaattca
     5041 acttcgttaa gagatcctgc ctgtgttgcg tggtttccaa ggatattgtg aagggcagcg
     5101 tgaagcaaat gagtcgcagt gtggtttttc atgacacggt gacggcgatt gctatcaatt
     5161 gccaaggtat attcttggtt caaggcaagc ggtgcaagga cttcaactgt atgaagggct
     5221 tgaccatttg gggctttctg aacattggtc acagtagcca caatcttacc tgactcatcc
     5281 aagatttgtc cgtagtcagc tacctgtcca cccatttcag cataaaatga cgtttccgca
     5341 aagataagag aggcagttcc ttctgaaaca gctcctactt ctgcattgtc agcaacgata
     5401 gctaccaatt tagaagacaa ttggctagta ttgtagttga agacactttc tacagtgatg
     5461 ttttgaagag tttcattttg catacccatt gagccaccct tgacagctga cgcacgcgcg
     5521 cgttcttgct gttctttcat ggctgcttca aaaccttcac ggtctacagt cataccagct
     5581 tcttcagcga tttcttcagt caattcaact gggaacccat aagtatcata gagtttaaag
     5641 acatcttgac cagcaatgac agattgacct ttttctttca agtctgccac aatgccttgg
     5701 gcaaagtgtt gacctgagtg aagggtacgg gcaaatgatt cttcttcgct cttaacgatt
     5761 ttctcaataa agtcacgttt ctcaagcact tctgggtagt agctttccat gatttttcca
     5821 acagttggaa ccaatttgta aaggaaaggc tcgttgatac ccaatttttg accatgcata
     5881 gaagcacgac ggagaagacg acgaagaaca taaccacgac cttcatttcc tggaagggca
     5941 ccatcaccga tagcaaatga aagagaacga atgtggtctg cgataacctt gaagctcatg
     6001 ttgtcgccat cttggtcata aaccttacca gacaatttct cgacttcacg gataatcggc
     6061 atgaagaggt ccgtttcaaa gttggtctta gccccttgga taacggccac caaacgctcc
     6121 aaaccagcgc ccgtatcaat gttcttatgt ggcaattcct tgtattcgct acgaggaaca
     6181 gcagggtctg cgttaaattg tgacaaaacg atgttccaga tttcaatata acggtcgttt
     6241 tcaatatctt ctgcaagcag gcgaagaccg atattttctg ggtcaaaggc ttccccacgg
     6301 tcaaagaaga tttctgtatc tggtccagaa ggtcccgcac cgatttccca gaagttgtcc
     6361 tcaattggaa tcaagtgact tggatccact cccacttcaa tccagcggtt gtaagaatct
     6421 ttatcgtctg gatagtaggt catgtaaagt ttttcagcag ggaaatcaaa ccattcaggg
     6481 cttgtcaaaa gctcataagc ccaagtgata gcttcgtcac ggaagtaatc cccgatagag
     6541 aagttcccca gcatttcaaa catggtatgg tgacgcgcag tcttccctac gttttcgatg
     6601 tcgttggtac ggatagcctt ttgggcattg gtaatacgtg gattttcagg gataatggtc
     6661 ccgtcaaagt atttcttaag ggttgctacc ccagagttga tccacaaaag agttgggtca
     6721 tttacaggaa ccaaacttac tgatggttct actgagtgac ctttggtcgc ccagaaatca
     6781 agccacattt ggcgtacttg tgcactagat agttgtttca tattgtctcc ttattcactt
     6841 gtttaatgtg attggctttc cagcatttcc acatagtcaa tcgcgacaca gagggaaatg
     6901 actaggtctg cataagcgtc ttcaagaacc gttacggtat aggtagaggt cagatggaag
     6961 agttccttct taatttccgc aatcaactga tcgcgatcat ccagcaattt gaaattcaaa
     7021 tcccagatat tgccctcgat acgaagacct agattatcaa actcatactt atctcgccag
     7081 aaggtcaact tcttacgaat gacaaaactc gagccatccc gaagctgaat ctcaaaacga
     7141 ggaagcaagg tcaagatttc tttactgatc tgactgactt gttcaccagc cgcatcatag
     7201 atggtaaaag ttttgggaat cttaaaaaat gatccctcca cctgataggc aatttctccc
     7261 ctgtcatcct tgatagcgaa gcgttcgcct ccaagacgaa acttttgttt gacaagaaat
     7321 gttttcatca acacctccaa aaatcaaaag acaagctcat atcacgaagg gcgaaaaacc
     7381 gcggtaccac cttcattcaa tgaacttgtc attctcttgt tcttatgcaa ttgtatgatt
     7441 gagtagcatg acttcctagc ttagatggct cgcagcaccg ccatttctct ggactaagac
     7501 aagtgaaaat caattctcaa ctttcttatt ataacgtttt tttaagcttg cgtcaactgg
     7561 aaatgatctc cgttgaatta gaccaattcc ctacatctct gattactttt tcaggatata
     7621 ttttttctta ctgccatttt tctttttatc ccaaattttc atattactaa acacagctac
     7681 tagaatattt ccaaatataa aggtgcctat cacccaatat atggactcag ttgttaggta
     7741 ttgtcgatcc aagccatcct ttaaatggaa tagtatagca gtttggttaa caatcataaa
     7801 ggttggccag aaactttttt tgaaaaaagt agacattttc attatttgtt gccgctttct
     7861 gtaaggttaa tactcaataa aaatcaaaaa gcaaactagg aagctagctt caagctgtac
     7921 ttgagtacgg caaggcaacg ctgacgtggt ttgaagagta taggcttagt atactactag
     7981 gcaagcaaat aagcaaataa acaaataaac aactagaata gaaaaagata gggctctaaa
     8041 aactgacttc tattccttaa aaacgaacca gcttgactga ttcgtcttct tacgtttatc
     8101 tcctacttcc gatacatttt aaactgtagg aagaggtcgc tatatttccc tgtccattta
     8161 tggtcaaatt tctcataaac ttctaggtgt ttcatggttt caacatcggg atagaaggcc
     8221 ttatcttcct ttgtttcctc tgggagcaat tccttcgctg gtaggtttgg tgttgaatag
     8281 ccgacatact ccgcattttg gagagcattt tcaggtttca acataaagtt gataaaggca
     8341 taggctgagt cttgattttt aactgttttg ggaatgacca tattgtcaaa ccaaagattg
     8401 ctggcctctg tcggtaccac ataacgtaga ttttcatttt tttctaacat ttggctggct
     8461 tcaccagaga aggtcacgcc gattgcaaca ttattctgaa tcatgtagcc cttcatctcg
     8521 tccgcaacga tagccttgat atttggagtc agtttgtaga gcttatccac tgtctcttcc
     8581 aactgctgcg gatccttgga gttgaggctg tagccgaggg aattgagtcc tagtcccagc
     8641 acctcacgcg ccccatcaaa aagcatgata gaattcttat actccagctt ccaaaggtca
     8701 tcccaatgct caggcgcttc atctaccatg gtttcgttgt agacaattcc taaggttccc
     8761 cagaagtaag ggatggagaa tttattacct gggtcaaagg actggttgag aaactctggt
     8821 ccgatatttt cgattccttc aatttttgaa taatcaagcg gaaccaagag gtcttcgtcc
     8881 ttcatcttgt taatcatgta ttcacttgga atggcaatat cgtaggtcgt tccaccctgc
     8941 tttatcttag tgtacatggc ttcgttggag tcaaaagcct cgtactgaac ttgaattcct
     9001 gtttcttctg taaactgagt caagagttca ggatcgatat agtctcccca gttatagata
     9061 accaattttt gactatctcg actattgatt ttactatcta aatgagtcgc aattccccac
     9121 aagacaagga taatcgctgc aattcctgct aaaaatgaat agattttttt catgcttgct
     9181 cctccttctc acgagagata aagtaataac ctacaactag gataatacta aagagaaaga
     9241 ctagagcaga aagggcattg atttctagcg aaatcccctt gcgagcacga gagtaaatct
     9301 cgactgatag ggttgaaaag ccatttcctg ttacaaagaa ggtcacggca aagtcatcta
     9361 acgaataggt gaaggccatg aaataaccag caatgataga cggagtcagg taaggaagca
     9421 tgatttcctt aaacatctga aattgactag ctcccaagtc ataggccgca tgaatcatgt
     9481 cgccattcat ttccttgagt cgaggcaaga ccatcaagac cacgatagga atggagaagg
     9541 ccacatgact agatagaacg gtcaaaaagc caagtgaaaa cttgagttgg gtaaagagaa
     9601 tcaagaagct agcaccaatc ataacgtcag gcgcaaccat gaggatatta ttgagtgata
     9661 gaaaggcttc ttggtatttc ttacgagact ggtagatgta aatggcacca aaagtcccga
     9721 taatggtcgc tatcaaggct gataggaagg ccaagaaaaa tgtctgagcc aaaatcagca
     9781 tgagtctccc atctccaaac atggtttcaa agtgagtcca gctaaaacct gtaaagctat
     9841 tcatatcatc accagcatta aaggcatagc caatcaagta aaagataggc aggtagagga
     9901 ccagaaagac cagtcccaga taaaggttgg caaatttttt catcgttctc tcctttcctt
     9961 agtcacccac atggtgatga acatggtcag gatgagaatc acaccgatag ttgaacccat
    10021 accatagttg tcattggtta gaaaattctg ctcaatagcc gtccccaagg tgataacgcg
    10081 gttcccacca atcaaacggg tcagcatgaa gagactcaaa cttgggataa agaccgactg
    10141 aaccccactt cgcacaccgt tcatagatag agggaagatg acatgacgga aggtctccca
    10201 cttagttgca ccaaggtcgt aactagcatt gatgagatta ttatccatat cgtctaagac
    10261 attgaaaatc ggcaaaatca taaaggggag ctcgatgtag cttgcgacaa agataaagga
    10321 aaaatcggta aaaagcaact gttgtgaacc aattccgata aattccaaga attggttaat
    10381 agagccattt tgaccaaaaa tcccgataaa agcataggct ttaaggagca aattgatcca
    10441 ggtaggaagg ataatcagca tgagccagag ttgacggtgc ttgagacggg tcaaaaagag
    10501 ggctgttgga tagctgataa gcaaggtcac aaaggtcaca atccctgcat aaagcactga
    10561 gttgaaactc attttgaggt aggtcaagtt ttgtgacgca aagtaagatt tataattttc
    10621 taaactaaac tggccttcaa tgttgaaaaa ggattgtccg aaaatcaaga ccaagggtgc
    10681 caatacaaag agggcaatcc aaagcatgta gggcactaca aagagtttag agcttgtttt
    10741 cttcatctct ttcctcctcg atcgcattga tcagacctgc ttcttgctct tcgatttcca
    10801 cgtattcttc gatacgagca tcgaactctt cttcggtttc attgagacgc atgatgtgga
    10861 tgtcttctgg ttcaaagtcc agaccgattt cctcacccac gatggcctta cgggttgagt
    10921 ggatcatcca ttcatttcca agttcgtcat aggcgataat ttcataatgc accccacgga
    10981 agagctgggt atcgacctta acttggagct tgccttcttc aggaagggta atgcgcaagt
    11041 cctctggacg aataacgacc tcaacaggtt catttggctt catcccacca tcaaccgctt
    11101 caaagcgttt gccgttaaat tcgaccaagt agtcctcaat catggtacct ggcaagatgt
    11161 ttgactcccc gataaaggtg gcaacaaagt ggttgattgg ctcatcgtag atgtccacag
    11221 gggttccaga ctggacaatc tcgccatcat tcataacgaa aatccagtca ctcatggcaa
    11281 gagcttcttc ctgatcgtga gtgacaaaga caaaggtaat gcccaatcgt tgttgtaatt
    11341 cacgcaattc gtactgcatg tctgttctca atttcaagtc cagcgctgat aaaggctcgt
    11401 ccaacaagac cacacggggt tggttgatga tagcacgggc gatggccaca cgctgacgtt
    11461 gtcctccaga aagtttgcgg atggaacgtt tttcataacc ttccaactga accatcttga
    11521 gaacttccgc tacacgctgc tcaatttctt tcttatcaat tttacgcaag cgaagtggaa
    11581 aggcaacatt ttcaaacaca ttcatatgtg ggaacaaggc ataggattgg aagacggtat
    11641 gtacgtcgcg cttgttggtt ggaatatcat tgatacgaac accgtctagc atgatatctc
    11701 ctgtcgtcgc atccagtaaa cctgcaataa tgtttaggat agttgatttc cccgaaccag
    11761 atgcacctag aagggtgtag aatttccctt cttccaactc aaagttgatg tctttgagaa
    11821 ccttggtgtt gctgtcttca aaaactttag agacgttttt gaattcgata attggttttt
    11881 tcaattggca taaattcctt ctttttcata gattaaccga tcggggctct gtcaggtccc
    11941 cactacctct tgcagggagt aaaaccacct gcatacatct tcgctaccga taggctttca
    12001 cccaagatcc ggacttctct ttcaagcgta atacctgagt gttccttgac tttttcgata
    12061 accgattgga tcaagtcctc gtagtctttg gccgttccat ctgcgacatt gatcataaat
    12121 cctgcatgct tttctgacac ttctacgcca ccgatacgat agcctttcaa gccagcttct
    12181 gaaattaact gacctgcaaa atgcccgact ggacgcttaa agaccgagcc acaagatggg
    12241 tattccaaag gttgcttgag ttcacgtagg tgcgtcaagc ggtccatttc ctgcttgata
    12301 acctgatggg ttcctggagc tagggcaaat ttaactgaca agacaactgc accagactcc
    12361 tgaatagctg aatggcggta accaaaagcc aagtctttag cagacagggt ttcgatttct
    12421 ccatccttgg tcaagacctt acaagactgc aagatgtgag caatctcgcc accataggca
    12481 cccgcattca taaagacagc accgccaacg cttcctggaa taccacaagc aaactcaaag
    12541 ccagttaaac tatgacggag ggcaatgcga gttgtttcaa tcaagttagc cccagcttct
    12601 gcttcaatgg tatagccatc aacagaaacg ttattgagct tgtcacacaa gatgacaaat
    12661 ccacgaatcc caccatcacg aacgatgata ttgcttgcat tgccaagaac catccaaggg
    12721 atattttctt ggttggcaaa tttcacaacg cgagccaact caaaacgatt tcgtggaaag
    12781 accaaataat cagcctctcc acctactttt gtataactat agctatgcaa gggttcctta
    12841 aaacggatat caattccttc taagatttca agcatttttt ctcttacaga catgtcactc
    12901 ttccttttac aaaattcatt ccattatacc atttttagag acatttgacg accataaaaa
    12961 taccttgttt ggattttgca taagaaaaag aggttccccc ctttttatga ttttttacaa
    13021 aagatttcct tggttccata ggcgaccaga acgagctcca gtgctagaat cacttcaacc
    13081 aagactggat ttgtcaacca gcctacttgg aaaagagatg gtgccagatc aaagaaggca
    13141 tgcaagccat aggctgctag gagataaatc catttcttct ggcgaacagc ttggtaaacc
    13201 caaactgtca aaagtaattg gaaaccaagc gccaagattc gctcaaaacc aagcaaataa
    13261 atctgccaga ccgaaagtga ctgaatggtt tttaacatat tttcagacag taattgcata
    13321 acctgtggat tctgagtttg aactgccgaa agaacgatgt aaagattgag taaactaata
    13381 aggcctagaa aaatcaactc caagccacca tgccctaggc cataggccaa ggcatctgcc
    13441 ttttccaaac ttctcttttt ctccaaccat ttgaagaaaa caagacgagc cgtttcctca
    13501 aaaaatgctg ccatggctag gccatagata atatagataa gcggatgatc ttgcaagagg
    13561 gcaatactac cgtctttttg aggatgcaaa atcaagatat gcaccagttt ttccaaaatc
    13621 tgcgaagaga caaagaaagc gactgcaccc aagcccaaga cagctagatt aatctggtat
    13681 ttctttttgg caaaccaaat gcttcctatc agaaaagcta gcaacagcaa catggtaata
    13741 atgatatgaa tggtcatttt cttctcctat tctgcctttt caatatcttt tttcatctcg
    13801 tcaacattga acttagcaaa caagtattga cggtcttgga ctgggaaacg ttggtccaac
    13861 tggtcaactg ctcccacctc gataatgcct tccttgatga caaaatccat gacatgtcca
    13921 ccgaaggtca aatcatctga tatgaagtgc agatggtagc ctgccacact gaccccatgg
    13981 aaaatctcag gcgtccagaa accaacaata gtccccgcaa cattgtcacg actatattcc
    14041 ggttgatggg ttgcgacatc agcaaacttg gtatcgggtg ttgacttagg aatcatacgc
    14101 acatgcatat gtgaaaattc cccccgaatc ttgatagagc ggaaaagatt ttccccatca
    14161 taataagact caattcgttc tttcaattcc ttgtctgtca tctcaaagcg ctggcggaaa
    14221 atgacctctg cctgatgcgg taccactgca gcgtaaggaa taagggcatc tggtgacact
    14281 tccacaattt ctggctggtc tcctgaccct ttggcctgat aagccttgcc atccaagaca
    14341 atcaattccc catcaatgga atccaaggtt cccaaaccaa ggtcaccatg ttctagcaat
    14401 tctcctactg tcatagtacc accataaagg ccagccatca aggctccaag agtattgtat
    14461 tgaaataatt tcactggttc ctgcacgttc ttatccattc actttcttgt ctgttattct
    14521 ataaatctta ctcctaagta taccacattt gcccctagat gtgaacgaga gaaacgctct
    14581 agacattgcc aagaaggaaa aaaaagggta caatgtaaca aaatcaaggg aggtctggaa
    14641 tgaagaaaca aagcaagtac aaagaggtcg tttcctatct gaaaaatggt atcgagtctg
    14701 aacgatttcc gacgggtagt cgcctgcctt ctatccgtca actgagcctt gactttcact
    14761 gcagcaagga caccattcaa cgagccctgc tggaattacg gcacgaacaa tacctctatg
    14821 ccaagcctca gagtggctac tatgtattag aacaagggca acatcaagac ctagaaatcg
    14881 aggttaccga cgaacatgcc agtgcctatg acgatttccg actctgtgtc aatgaaacct
    14941 tgattggacg agaaaactac ctcttcaact actatgacaa tcaagaagga ttagaagacc
    15001 taagacagtc cattcacaaa ctcctatttg agcaagctct ctactgcaag gctaaccaac
    15061 tagtactgac ttctggaacc caacaagcct tgtttatcct ctctcaaata tcctttccta
    15121 gacaagccaa ggaaatcttg gtggaacagc caacctacca tcggatgaat cgcctcttga
    15181 ttgcacaggg gctggactat caaacgattg aacgaggcat tgatgggatt gacttggagg
    15241 agctggaagg ccacttcaaa acaggaaaaa ttaaattttt ctacaccatt cctagatttc
    15301 actatcctct gggacattcc tattctgagc aagacaaacg atctattctt aacttagctg
    15361 ccaagtatga tgtctatatc gtagaggacg attatctggg tgatttggac tccaagaagg
    15421 gccaaacctt ccactatctt gatacagagg agcatgtcat ttatatcaag tccttctcga
    15481 ccagcctttt tcctgccctt cgtattacag cactcattct tccaaatgct atcaaagaag
    15541 catttgtggc ctacaaaaat atcctagact acgacagcaa cctcattatg caaaaggccc
    15601 tgtcactcta tattgacagt caattgtttg aaaaaaatcg tttggctcgc ttgaccaatc
    15661 atgaatctta ccaaaaacaa atcgaggaaa ggataactaa aacaccttgt ccccttcctc
    15721 attatcccct acacgatggt ttattgctag acctgagaca gtatcctaaa atcgccagtc
    15781 tcaaacacag tcaactgggc ttggacttct ttgaagaggc ctatttaagc acctgtcctt
    15841 atcaatttgc caaggtgtcc ctagacaatc tggaaaatgt tttaaactat ttaaaagcag
    15901 aattggaatg acatccaact ctgctttttc ttattcttca acttcagtta gacttgctgc
    15961 tttttcaaga tagctttggt aagttccttc attcttaagt ttttggatga ccttgtctac
    16021 cacttctttc aaatcatcac tattttttct aagagcaacg gcattggcgt cgccgtcctt
    16081 catcttcaag ctgacagttg cgacagctaa gccagcgttt ttagcagcat aactaagtgc
    16141 aacaggctca tccatatgaa cagcatctac ttttccaacc tgcaattcat tgactgcttc
    16201 acccatatta gttagggaag ttaattgagc ttttggcaat tgttccttga ccattgattc
    16261 tggaacagtc cctttttggg ctgcaatatt agcactttct aggctagtta aatccttgta
    16321 tttttccaca tcagccttac gaaccaagaa actaatcttg ttttcatagt atgggattga
    16381 aaaatcaaag acttcttttc tctcgtcagt agcactaatt cctgcaactg ctaggtcagc
    16441 cttaccagtt tgaagactgg tcaaaacatt gtcaaaactc atgcttgaga tttccaactt
    16501 aaccccaagt tcatcagcga tagcctgagc catgtcgatg tctgcaccga ctacctggtt
    16561 ctttccatca accaatgatt gaaattcaaa gggtgcatag tcaggactgg ttgccacaac
    16621 taatttccct ttttgtttga tagcatccac agcagactga gaaccattag aacctgactg
    16681 acaagctact aagaagaaac ttgcaagaaa attacataaa acaaatatcc atttttttga
    16741 tttcataaat aaacaacctc tctgttaatt ttgtataatt ataacgatat ccaagttact
    16801 tgtcaagtgt tttttaaatt tttatctcaa aaatattttt tcgttcaaaa aaaggagcca
    16861 tcagttgatt tcaagctcct ttttatacag aattaaacta ttttataatt cgacaatctt
    16921 acctgtttca aagtagacaa cccattcaca gatattttta gcatagtcac cgatacgctc
    16981 caagtaggaa ataacttgga aataatcacg acccgtaaca atggcttctg gatttttctt
    17041 aatctcttca gtcgcaaggt cacggatagt ttcaaaatag tggttaattt gctcatccat
    17101 ggaggccacc cggtatgcgt cgtcaacaga accattaaga taaagatcaa gtgctgcttc
    17161 aacaacgctt ttaacttcac gtcccatttt tttaatttct tcctctacag ctgggatgcg
    17221 ttcttccccc ttcatacgga tggttgcctg ggcaatggct acagcgtgat cccccatacg
    17281 ctccacatct gatacagcct taaggacagt caagactgta cgcaaatctt gagagactgg
    17341 ttgttggagt gcgatcattt caaatgattt cttttccagt ttcacttcgt attcatttac
    17401 ttctgcatca tcttcgatga cctcttttgc caggtcacgg tcatgcgtga caaaagcacg
    17461 taccgtacga ttgatttgtg agagcacttc ttgtcccata gcgtagaact ggttatgtaa
    17521 tttctctaaa tcttcttcaa attgagatcg taacatcttt catctcctta tccaaatttt
    17581 cctgtaatat agtcttccgt ttccttgtgt tggggatcaa ggaacatctg cttggtatca
    17641 ttaaattcaa tcaaatctcc atctaggaaa aatcctgtct tatcagagat acgtgaagct
    17701 tgctgcatgg aacgggttac cagaagcatg gtgtacttgt cttttagacc atacaaggtt
    17761 tcctcaattt taccagctga aatcggatcc aaagccgaag ttggctcatc caagaggatg
    17821 attttaggac tagttgccaa gacacgggcc acgcagacac gctgctgttg accacctgac
    17881 aatccaatag ctgaatcata tagacgatcc ttgacctcat cccagataga ggcaccttgc
    17941 aaggcttttt ctacggcttc atccagaacc tgcttatcct taattccatt gatacgaagc
    18001 ccgtagacaa cattctcata gatagtcata gggaaaggat taggttgttg gaaaaccatt
    18061 ccgatttcct tacgtaattc aaccgtatct gtacgcggac tgtagatgtt gtgaccattg
    18121 tacaccacgg atccagttgt ggtcacctct ggattgagat ctcccatgcg gttgagagac
    18181 ttgaggaggg ttgacttccc tgatccagat ggaccaatca aggctgtaat ttccttaggt
    18241 tggaaagata gggaaacact attcaaagcc ttctttttat tataataaac ggacaggtct
    18301 gatacctgta aaatcgcatc tgtcatacgg tttcctttct aaccaaagtg accagataca
    18361 tagtcattgg tggactgtag cttggcattt tggaaaatag ttgcagtctt gtcatactca
    18421 atcaaatcac ccaagtaaaa gaagcctgta tagtcacttg cacgagcagc ctgctgcata
    18481 ttatgcgtta caatgatgat ggtaaagtct ttcttgagct caaacatggt ctcttctagt
    18541 tgcatggtcg caatcggatc caaggctgaa gctggctcat ccattaagag gatatctggc
    18601 ttaacagaga tggcacgagc gatacagaga cgttgttgct gaccacctga taaggtcaag
    18661 gctgacttgt ggagatcgtc tttaacctga tcccagaggg cagcctgacg aagggaggtt
    18721 tctacgattt catctaggac ttgcttatcc ttaactccag cacgttcatg cgcaaaggta
    18781 atattacggt aaattgactt agcaaatgga ttggggcgtt gaaaaaccat tccaatgtgt
    18841 ttacgcattt cataaacgtt gatttctgga cggttgacat caattccacg atagagaatc
    18901 tgcccagtta ctttagcaat atcaatagta tcattcatgc gattgagact gcgtaagtag
    18961 gtagatttcc ccgatcccga cggaccaatc aaagctgtaa ttttatttct ttcaaattgc
    19021 atatcaatcc ccttaatgga ttcattttta ccatagtaaa catggacatc cttagtagaa
    19081 agggctactt tttcttcagg aaaggtaagg atatgcttct catcccagtt atatgttgac
    19141 atggcttctc ctttaggcag cggttaattt cttgtgtaga tagcttccga acttacgagc
    19201 tccaaagtta aaaatcagga taaagatcag gagcacagcg gcagaacctg ctgatacaat
    19261 ggttccatct ggaatagtgc cttcactatt gactttccag atatggacag ccaaggtttc
    19321 tgcttgacgg aagatagaga tggggctagt cacactgagg atattccagt tagaccagtc
    19381 aagagctggc gccgattgcc ctgctgtata gatcagagct gcagcttcgc caaagatacg
    19441 accagatgcc aagacgacac ccgttacaat acctggaagc gcttctggaa taacaacatg
    19501 aaccactgtc tcccagcgag aaatcccaag agccagacca gcctcacgtt gggtatggtg
    19561 aacgtgtttc aaactatcct ctacattacg cgtcatctga ggcaagttaa agactgtcaa
    19621 ggccaaggca cctgaaatga ttgaaaatcc atactcaaac tggactacaa agatcaagta
    19681 accaaagaga cccaccacca ctgatggtaa agaggacaag atttcaatac aagtccgcac
    19741 aaagttggta acaggacctt ttttagcata ttcagccaag taaatcccag ctcccataga
    19801 aagaggtaca gaaataatca aggtaatgac caataggaaa aaggaattgt aaagctgaat
    19861 gccaatccca ccacctgctt gaaaagcaga agaccttcca gtcaagaaag accaagagat
    19921 atggggcaag ccccgaacca agatatagag aatcaaggaa gccaagattg tcacaatgat
    19981 gctagcaatc gtatagagga cagctgttgc aagtttatct aatttcttag cgcgcataat
    20041 ttttctttcc tctttctttc gtaatcaatt taatcacact gttaaaaact aaactcatca
    20101 agagcagtac caaggccagt gaccagagaa cattattatt tacagttccc atgacagtgt
    20161 tcccaattcc catagttaat atagaagtta aagttgcagc tggtgtggtc aaggaagttg
    20221 ggataacagc tgagtttccg acaaccatct ggatagctaa agcctcacca aaggcacgcg
    20281 ccatcccaaa gaccactgca gtgaaaatac cagaacgggc cgccttcaag atcacacgcc
    20341 agatagtctg ccagcgagtg gctcccatag cgaaactggc ttcacgataa taacgaggaa
    20401 ccgcacgcaa gctatccgtt gtcataaagg ttacggtcgg caaaatcatg acaaagagga
    20461 cggaaatccc tgacaaaatc ccaaaaccag tcccaccaaa gacactgcga acaaagggaa
    20521 cgacgacttg caagccaata aatccataca ctactgaagg aatcccaacc aggagttcaa
    20581 tagctggttg caaaatcttc gccccttttg gtgatacttc ggtcataaaa actgctgcac
    20641 caatagcaaa gggtgttgcg ataagggctg agagaatggt aacgataaag gaacccaaaa
    20701 tcataggaag ggcaccaaat tctttactag aaggattcca agttcctccc aaaagaaagt
    20761 caaagatatt cacaccattg acaaagaagg tcgacaagcc tttttgcgct acgaaaacca
    20821 aaatcatggc cacaaggatg actatcaaag aaagacaggc aaaggtcaaa ccttttccta
    20881 atttctccag acgagaattc tttgatggaa gcaacatttt cttagctaat tcttcttgat
    20941 tcattattgt ctcccttcca acactgtcac agttccggca gcatcttttt caaccttcat
    21001 ttccttaatc ggaatatact tcaatccttt gacaatccct tcttgggtct catccgagag
    21061 aacaaaattg agaaattctg cagccaactc attgggctgc cccaatgtat acatatgctc
    21121 ataagaccac aagggccaat tattgctact tatattttct ggacttaagt catagccatt
    21181 caacttcatg cttttgaccg aatcatctat ataggtaaga gataaataag agatagctcc
    21241 tggacttttt gatacgattg attttaccgc tccatttgaa tcctgctcct gactttgcat
    21301 ggcagactga ccttccataa tgacagtatc aaaggtagca cgagagccag agccggctgc
    21361 ccgattgata acagagatgg gtaagtcctt accaccaacc tctttccaat tggttacctc
    21421 acctatgaag atttgacgaa gttgctctgt cgttaggtta tcaacatcaa cctccttatt
    21481 gacaatcaga gccaagccag ctaccgcgac cttgtggtca acaagagcag aagcatcaat
    21541 tccgtctttt tcctcagcaa atacatctga gtttcctata tcaactgccc cagactgaac
    21601 ctgggacaag cctgtaccag aacctccccc ttggacattg accgtttttc caacatgaat
    21661 cgtgccaaat tcatctgccg ctacttcaac caagggttgc aaggcagttg agccaacagc
    21721 cgttatggat tctccacgat caatccagct agcacagcct actaaacaag ccgtcagcca
    21781 aaaagcgata agagacagag caagcttttt tctttttttc actgtttttc tcctcgaaaa
    21841 taattatgaa tactgtgaat tttttaagta gttctttatg agttgacgca tgaattctta
    21901 ccaaatttct gcgcaattga ttatttatat aatataggct atattactct ttcctaacct
    21961 ccttttttca tatgtggata aaatctcttg tctatccctt ccaccattgt cacccattat
    22021 agtcatttcg tgtctctttt tccccttttt aatgcaaggg aaattactct cctcagatga
    22081 taatccaaaa gctagaaagg tatctcaaac ctctctactc tcccagacta gtttacaact
    22141 aaaaggaaaa gattctattt tatgagaaat ctagtttaca agcggtaaga acgctaataa
    22201 ctaaacttct tgtactcttt gaaaatctct tcaaaccagt gttttgagct atctatggct
    22261 agcttcctag tttgctcttt gattttcatt gagtagtaaa actacatgta atggcaatca
    22321 agatatcaag aatcatccta ctaaaaaaat ccatactttc actataacat agaataagat
    22381 atttgactag cattttcatt tgaatctgag gccttttgga aaataatttt tcaaaacatt
    22441 tccagtaacc tttgcaaagc ccaagccatt gcctttaacc aaaacttggt accaaccatt
    22501 tggcagactt tctgccagct gaacgatttc tccagccgca tacttgacaa acgcttcttg
    22561 gccaatttca accgactgtt cgacctgact cggtttcaag gctaaaccaa gagcgaaact
    22621 gggctcaaag cgtttcttct taaaagtgcc cagatgcagt ccattgcgag caatcttgag
    22681 cttccctaaa tctggcaaaa gttctggcaa gagataaagc tggtctccaa aagtctgcaa
    22741 gatacccggt agattgacct tcaaatggtt ttgggcaaat tcctgccaca aggcaacttg
    22801 ttcacggctg aggttactct tacttgcctt aaatttagga gctggattgt tacccttaaa
    22861 ctgtagatgg gcaacaaact gaccctctcc cttaaactga tgaggataca tccgagccgt
    22921 ttctggcagg tcaataccag ctaccattcc attgatatgc tctactggca acaagtcaaa
    22981 atcatactct tccagcaacc aattgacaat ctcttcgttt tcctcgggtg cccaggtaca
    23041 ggtcgaataa accagatgac caccttcagc taacatggtc actgcatcct ccagaatttc
    23101 tctttgcaag ctagcacatt gactcggata atctaagctc caatagtcca taacatcagg
    23161 ttgcttacga aacattcctt caccagagca aggggcatca agaacgatta agtcaaaata
    23221 gcctttaaag accttgacca agcggtcggc agattcattg gtcaccacga catttgtcgc
    23281 tccaaaacgc tccatgtttt caaccaaaat cttagcccgt ttgcttgaaa tttcattgga
    23341 aacaagtagc ccctcccctg ctagataggc tgccagttga gttgatttgc cccccggtgc
    23401 agcagccaag tccaagacct tcataccagg actgggttgg gctacttgag ccaccatttg
    23461 agcagcaggt tcttgcgaat aaactaaacc tgtagcatgc tcaggcgatt tccctgaaac
    23521 cttcccatag tggccccaag gggtttgagt aatggcatca gaaaaggaaa gttgctcttc
    23581 ttttaaggga ttgacccgaa aggccgaaac cgcttcctcc tcaaaagagg caagaaaatc
    23641 tcttgcctca tctcctagta tctctttata tttttcaaca aatccttctg gaaattgcat
    23701 ttaagttctt ttcctttcgt aaatatagga ctgaatttcc tcctgcatct caagaggcac
    23761 catcatgacc ggctgtctgg tttgaaaatc aggagcttca ccaaaaaggg tcacaacccg
    23821 atagcccaga ctttccccta aaatactagc tgcggcataa tcccatggtt gcagataagt
    23881 gagataggtc aacaaacgcc ctgacaaaat cttggcaaaa ctaatggccg cacttccata
    23941 gacacgaaca ccaagaaccg atcggctcaa atcagccagc ccccattcat tggtttccag
    24001 cataccacta ttccctgcaa tgagaaaatc tccaagtggt ttagttttaa aaggagctag
    24061 gggcctatca tttagacaaa ctggaaattc cccaccaccg tggtaacaat cccctttgac
    24121 cacatcataa atcagaccaa actgtccctg accattttca aaataagcca tcataacagc
    24181 aaaatcttcc tgctgggcta caaaattatt ggtaccatca atgggatcaa tgacccaaac
    24241 cttgccctct tgaaccgagg ctcgcagaca accttcttca gcacaaatct tatcctcagg
    24301 ataacgggac aaaatctcac caaccaagag ttcctgaact tctttgtcca gtctggtcac
    24361 caaatctgtt gaagaggact tggtttcaac acgcaagtct tcctgcatat ggtcaagaat
    24421 gtactggcct gctttcttaa caagctcttt agcaaattca aatttacttt ccaagagaaa
    24481 tctttccttc ccctttttct ttggcagcct gaactgctcg gtaaagtgaa tagccactaa
    24541 ccgtttcaaa ttctcgtccc aaacgtttct cttcgctctt gcttggcacg accgctttga
    24601 atcccttata ggagtccagt aactttttag cctctacttt gccttcatag gcagcttcaa
    24661 catcattaaa aaaagaaagc actgaagcaa gttcttcagt gctccacgac aaatctagtg
    24721 ggtaactata ctgtttgttc attaactaat accagctctc attcttgctt cttttagttc
    24781 ttgcttacga taactacgag ggagaaaagc acgaatctca tcttcattaa aaccgatttg
    24841 catacgcttg gcatcaataa taattggacg acgcaaaaga ctaggatact gctcaatcaa
    24901 atgaagcaat tccgataccg aaatactctc tacatcaata ttcaattttt gaaaaatttt
    24961 tgaacgagtt gaaatgatgt catcagtacc attttcggtc aaggaaagga tgtgttgcaa
    25021 ttcttttctt gttaaaggac tggtcataat attgtgttcc acaaagggaa ccttatgttt
    25081 ttctaaccag gccttagcct tacgacatga tgtacagctc ggtgatagaa atagtgtaat
    25141 catgcttttc tcttcttatc tatactttgc tacttctatt atacaaaaaa ataaggcgct
    25201 tgactaggga tttttagaaa aaaagcctat tttttcaaga aaaataggct gtttgcgaac
    25261 gattgacaca attggatttg gttaattcac tcttaacgat ggttttaaac gatatatatt
    25321 tttatatatg caaattaaaa acatctttca tttcacttcc tacgactttt cagacacaga
    25381 tacccaaaga agctttcata gagggcaaaa aagaggagga aggcatgaag aaagaaggtc
    25441 tctggcaaaa tcataataac aggatccttg gctggatcaa aaagccaggt atcatctccc
    25501 acaaagagaa tttgatggaa aagagtaaag aattggtcaa aaccaatcaa aactccccca
    25561 agtccaatca tcacaggtaa gactactaga gtcaggagac tttttcgata aagagacaaa
    25621 aagtcctttt tcacaatcct attgacaaag acatagaaac ttggcagtgt cactagagct
    25681 actagctgaa ccaaatgaaa gagattcttg accactgcga aatggtgcag accagctgct
    25741 gacgaacgaa aatcaggcat ctgtaagacc tgactaaaag gattggtcag ataattcatc
    25801 aagatatgaa aattgtattg aatggtttct ggttttagat agactcgatt cgttaagttt
    25861 agccactgaa tctccatagg atagaaaatc caagccagat aaatggtcag aaggattgag
    25921 agggagagga gaaagagcat agagccccaa aaggtcaatt tagttttcat caaaatccca
    25981 ctccgcaagg ctagaaacca catgtgtcgg tgcgattggc aggccagcta cttcttctgc
    26041 cttggtaaaa cctgtcgtca ccaagagtgt tggaatgcca ttgtcaatcc cagcccggat
    26101 atcagtcaaa taattgtccc caaccatgat taactcttca cgttccaaac ctaagtgctc
    26161 aaccgccttg tccataatga tggcatttgg ttttccgata taaaccggct tcactcgtgt
    26221 cgctacttca agcagcgtaa tcagtgagcc agcacctggc aaaagaccac gttccgtcgg
    26281 gatgttgagg tcaggattgg ttccgataaa atgggcaccc ttttgaatag caagagttgc
    26341 tgtggcaaat ttttcatagt cgacttgcca atccagacca actaccacgt aggcagggtt
    26401 ttccttgtct tccacataac cagccgcctt gatggcttcc ttgagtcctg cttctccgac
    26461 gacatagacg gtcttttcaa gccccaaatc attcatatag tcgatggttg ccaaagtcgc
    26521 tgtgtagaca gtcgatagag gcgtatcgat attaaaattc tgagccaaca tctccttaac
    26581 actctctgga gtgcgggttg tattgttggt tacaaagaga tagggaatgt cccgcttttg
    26641 caattcatga acaaaagtct ctccagcagg gattcggtct ttccccttat aaatggttcc
    26701 gtctaaatcg attaaatagc ctttatattt catctatttc tccctaaacc ttttttattt
    26761 cttgccaagt aatgattgct tgggcattga taaccccatc acttgtaatt tcatgcttgc
    26821 tttccagtcc agtccgttca acagccgatg taatcacccc acctggtcga acttccttga
    26881 catacttgag gttgattttc ttgggaatat agtgggtcaa aaaatccgct cccatgacct
    26941 caaaaatcca gtccaagtat ttactgttat tgacatgacc attcatatcc aagtcgtaaa
    27001 aacgaacatg gtaatccttg ctgatcggct cttccaagga ttcatacttc ggtccacgga
    27061 taagtttttt atcaaaatca gactggtaag gagccacaat ctcaggttca acagcatgga
    27121 cttttcgact gtcgcggtcc atgagaacaa aggtcgccat catatggatg agctcctgcc
    27181 ccgcttcatt ataaatagta aagcgacggt agcaaaaaag tcgattgtag ctcaaggctt
    27241 ccgtttcgat ggtaatttct tccgcaaaac gaggcaaacg aaccacctca atatcatatt
    27301 ctgcgataat ccagaccaga ttatagtctt ccaaaatggc cttatcacta actcccagtt
    27361 caatcgattg catccctgaa acttgcagtg acagcaaaat cacatctgga agtttgatat
    27421 gaccgttcat atcagccata tcaaaaggaa ttttcatttt catttgataa gttaagccca
    27481 tgatcctact ccaaaataaa tcgttctgct acagtatctc ccaaaaagag acctctcttt
    27541 gtcatgcgaa cgtggtcacc ctcaatctgc atgaggcctt gttgaaccaa atctctgaca
    27601 atttctccat aaagtccagc aaaagactgt ccaaattttt cctcaaatcg cgccatggaa
    27661 accccggatt tcttgcggag tcccaagaac atttcttctt ccatttgctc cttttgactc
    27721 aggtgatctt ctgtaataca agcattgcct tcctcaaccg cactgagata atgacgaatg
    27781 ggaccatgat ttttatagcg tactccattg acataaccag atgcccctgc accaatacca
    27841 tagtattcag cattgtccca gtacatgaga ttatgacgac tttcaaaacc gggtttggag
    27901 aaattagaaa tctcataatg ctcaaaaccc gctcgctcca gctctgcaat gatgtactca
    27961 aacatctccg cttctagttc ctccttaggc agaggcaatt tcccacgtcg catccggttc
    28021 ataaagaccg tatggttttc taaaatcaaa ctatacaaac tcatgtgggg aatatccaat
    28081 ccaatggctt tagccacatt ttcctttact tgctccatgg tctgaccagg cagagcataa
    28141 atcaaatcaa tggagatgtt gtcaaaacca gccagtttca ggcgatcgat attttcataa
    28201 atatccttct ccaaatgact gcgcccaatc tttttcaaca tcttatcatc aaaggtctgg
    28261 acacctagcg aaacacgatt gacagccgaa tttttcaaaa cagctatctt atccgcatcc
    28321 aaatcgcctg gattggcttc aatggtcaac tcttccaaga cagacaaatc caagttttta
    28381 gtcaagccat tcagtaacac ctccagttgc ggagccgaca gggctgtcgg tgttccacca
    28441 ccgatataaa gggttgacaa cttttcaata tcataagaac gaaactcttc cagcagatgc
    28501 tctaaatagc tgtcgactgg ctgatttttg atgaagacct ttgaaaaatc acaataataa
    28561 caaatctggg tacaaaatgg gatgtgcaca taggctgacg ttggtttttt ctgcatagta
    28621 attattatac cacaaagact agattccaga taaaaatcac catccccaga tacatagtcc
    28681 gtccggagat ggtgatggtt tattcttctg ttatatgaat cacaatctct tctgagtcat
    28741 caagagcttc ggctttttct tgccattgtt ccttgagatt atttaattga ttttttgatg
    28801 cttctgtcgc ttgaaaagca taggatttag cttgagcaag tatactgtcc acagtgattt
    28861 cacctgactc aacctgttct tttgttttca gaacaaaatc tgtagcctgc tccttaactt
    28921 ctgtcagttt ttcacagact tgctccttgg catactccgg atcttctctc aaatcatcta
    28981 gaaaatcttg agcctgactg caaacttgtt tgcccttatc acttgttaaa aacaaggcaa
    29041 gagctgcacc tgaaaccgtt cctaaaagga ttgaggataa tttacccata aggattctcc
    29101 ttttttattt tttgaaaaat ttacttgcaa gacgaagagc tgacagactt gcaccagtct
    29161 tgagtgtttt tgaaccagct gatgaagctt tcttgctcaa gacacgcgca tggtcattga
    29221 ggtctgaaac agatagagat aaatctgcaa cagcactgaa gagtggatca atcgtagcca
    29281 ccttgacatt gatatcatct gccaagacat tgaccttagc caacaactca ttggtgtgat
    29341 gcaaggtcac atccacatct gaagtcaagg ttttaatcgt cttttctgtt tcatcgatga
    29401 cacgaccaag cttttgtaca gtaatgatca gatagaccaa aaagacaatc aaagctaggg
    29461 caacaagaat atatgcaact tctaacattt agttttcctc ctctgtaata tagtaagggg
    29521 ccttctttcg attttgataa ataacgatca ttataccgag accgataagg acaactgaca
    29581 gccattggga cactcgaagt ccgaagaaca tgagactatc tgttcgcata ccttcgatga
    29641 ccatacgacc gaaaccatac caaatcaagt aaaaggccgt gatatgacct cgtctgagac
    29701 tcttccattt ccgtctaaaa atcagaatca aggcaaagcc aagcagattc catagagact
    29761 cataaaggaa agtcggttga cggtagctcc cctcaatata catctggtca cggataaagc
    29821 caggtagata atccagatta tccactgttg caccataagc ttcttggtta aagaaattac
    29881 cccaacgccc caaactttga gcaatcataa cgctaggcgc cgcaatatct agaaaatccc
    29941 aagtattgat gagtttacgg tcagcaaaga tatagagcac aagagcccca gttatcaaac
    30001 caccgtaaat ggccaaacca ccattccaaa tggcaaaaat ctctcctaaa ttctgactat
    30061 agtaatcaaa tcggaaaata acatagtaga gacgagctcc taaaatagcc aagggaaagg
    30121 ctactaagat aaaatctaaa atatcgtctg gtatgatctt ctttctaggt gcttctttca
    30181 tggtcaaata aaccgcaaga atcaagcctg tcacaataca taaggcatac caacgaatgg
    30241 ctaggggtcc tagttgaata gcaattggat caagcatttt gcacctcatt tcgagcgatg
    30301 agacttgtca gtcgttcgtc gaacaaacgg gtcgcatcaa agcccatttc cttggcacga
    30361 taattcatgg cagctgcctc aatcacaaca gagatattac gacctgtttt aactggaata
    30421 cgaatacgag gaatggctac gccagaaact tcaagttcct ctgcattgtt tccaagacga
    30481 tcaaaggtct tatgcgtatc gtaattttcc aaatagacag caagctgaac ctgtgaagaa
    30541 tccttgacag cactcgcacc gtagagactc ataacatcga taataccaac cccacgaatt
    30601 tcaatcaagt gtttcaaaat ttcagctggt tcaccccaga gagtaatctc atccttggca
    30661 aagatatcga cacggtcatc ggctaccaaa cggtgaccac gtttgacaag ctcaagacct
    30721 gtctcactct taccaattcc actatctccc tgaatcaaga cgcccatccc ataaatatcc
    30781 atcaagacac cgtgcacact ggtacgttct gccaaacgag aatccagata gctagataac
    30841 tctccagata aacgactggt agctgcacgg ctggttaaaa tagcaatctt acattctcta
    30901 gcagccttta acatctcctc tggaaccacc aaaccacggg caacaatgac tgctggtgtc
    30961 tcaggtagaa acattttttt caaaacttca taacggctgt tggaaggcat gctgatcaga
    31021 taagaccact ccttcatccc caaaagttga atccgctctg gtgtatagta gtcaaaatag
    31081 cctgtcattt caagaccagg tcgcgtaata tccgctatat tgatttcctt ttcaagcaat
    31141 tctggttcac catagacaat gtctagtcta agcttttcaa tcacttcttt tactaaaacc
    31201 gacatcattt cctccttcaa atgagttctt ctctctatta tatcaaattg taggaggaag
    31261 tttcagattt ttgcaggctt tggagtattt atttaaaaga aaaaggacta gatttctcta
    31321 gcctttcatt tcaattagaa ttttttacgt ttacgagcta cttctgattt acgtttacgt
    31381 tttacagaag gtttttcata gaattcacgt ttgcgtgttt cttgaagagt accagcttta
    31441 gtaaccgcac gtttgaaacg gcgaagtgcg tcgtcaagag attcattctt acgtactact
    31501 gttttagaca tttttttcac tcccttcaag ttcaatatct atttcattct acacgtaaaa
    31561 ggaataattg tcaagcaaaa atgcggttta attttgattt tttcttccat ttatacaaga
    31621 gttgaaagcg ttcaatagaa cattgctttt ttatttttcg agtaagctaa gcgcttcagc
    31681 atctgcgatg atggttacat cagggtgatt ttggaggcta cttgcaggta ggttctcagt
    31741 cactgggcca gatactgttc cggcaatggc ttctgctttc gactcaccgt aagcaaaaag
    31801 aataatagac ttggcatcca aaatgttttt aatccccatt gaaatagctt gggttgggac
    31861 gtcttcaatc ttggcaaaga agcgtgcatt ggcttcgata gtagactggt caagttctac
    31921 tagatgcgtt tgactgtcaa atggagtacc aggctcatta aagccgatat gcccattgcg
    31981 accgattccc aagatttgga ggtcaactgg atggtcagcc aaaatttggt tgtagcgttc
    32041 aacttcagct tcagcattgt ccttaacacc acgaggcaag aaactttctt taaatggttt
    32101 ttggttgaac aagttttctt gcatgaagta acgataagac tgtggattgt ccccatcaag
    32161 gcccacatac tcatcaaggt tgacactggt tagatttgaa aaatcaaggt tactctcaac
    32221 aatttccttg taaaattcaa gtgggctact tcctgtcgca agtcctagag tttgagctcc
    32281 attagccaat ttttccttca aaatctcaaa agcaactttt ccaccttgaa cttggttttc
    32341 aactttaata actttcatct tttcatcctc catttctgtc tatatttatt atatggtata
    32401 gaccaatttt tgtcaagtga aaacgattta atttctaaaa aaagagcgtc caaacttgaa
    32461 acgtgttata atggatagga ttagaactta gaaagaatga acagatatat gaatacagct
    32521 gattttgatt tccacttgcc agaggaattg attgcccaaa cgccccttga aaaacgtgat
    32581 gcctccaaac tcctcatcgt caaccgtgag acaggagaaa tgcaagataa acacttccac
    32641 tctattattg atatgctgga acctggtgat gcccttgtca tgaacgacac ccgagttctc
    32701 cctgcccgcc tctatggtca aaaagtggag acaggaagtc atgtggaact tctcctcctt
    32761 aagaacacta gtggagacga gtgggaagtt ctggctaaac ctgccaaacg cctcaaggtc
    32821 ggtactcgta tcagctttgg tgatggccgc ctcagcgctg tcgttacaga agaattgacc
    32881 cacgggggac gcattgtccg ctttgaatac caaagaattt tcctagaagt cttggaaagt
    32941 ctgggagaaa tgcctctgcc accttatatc cacgaaaaat tagatgaccg tgaacgttat
    33001 caaaccgtct acgccaagga aagcggctct gctgcagcac cgactgctgg tcttcacttc
    33061 accaaagaac tgctggcaga aatccaagct aagggtgtcc atctagtcta tctgactctc
    33121 catgtcggac tcggaacctt tagacctgtt tctgtggata atctggacga acacgaaatg
    33181 cactcagagt tctatcaact ttctgaggaa gctgcggcca cccttcgctc tgtcaaagaa
    33241 aatggtggtc gtgtcatcgc tgtcggaacc acttctatcc gtaccttgga aactattggt
    33301 tccaagtttg atgggcaaat ccaagcagat tctggttgga ccaatatctt tatcaaacct
    33361 gggtatgagt ggaaggtcgt ggatgccttc tcaaccaact tccacctgcc aaaatcaact
    33421 ctggtcatgt tggtttctgc ctttgcaggc cgtgaattag tcttagatgc ctaccaccat
    33481 tccatccaag aacactaccg cttcttcagt tttggtgacg ccatgtttat ttattgagaa
    33541 agaatttctc taaatcttct aataccaata aatcgctaag atattatttc aaagaacatc
    33601 tacaattgaa actctagcta gctgtagaag acgcctagta cattgaaatt aaaatgcaag
    33661 acacatgagt agcaccatat ttgttgctct tatctgtcct cgcaagagac tattatgagt
    33721 tatttcagaa tcattcacta ctttgaccct gactctcctt agtctcaaaa tcaaagactt
    33781 atactcttca aaaatctctt caaaccgcgt caacgtcatc ttggattata tatgtgactg
    33841 acttcgtcag ttctatctac aacctcaaag cagtactttg agcaacctgc gactagtttt
    33901 ctagtttgct ctttgatttt cattgagtat taaacaaaaa gtgaacaaag ctgaattcta
    33961 atgtacagaa gactaggctt gttcactttt ttatagtcgc tataagatga ccttatctat
    34021 agctttttat atataattat atattcagac atactattat caattttgtc gcagggagga
    34081 atctgttaac gcacccattc accattatca ttgactctat agccatctat acttgtattg
    34141 accgctaact cacccgatgt atttacataa taccatttac caccaacttg gaaccattga
    34201 ttgactttca tagaaccgtt gctgttgagg tagtaccatg aaccattaac ttgtacccaa
    34261 cctgttgcca tggaaccatc agtattataa aaataccaca taccattttc ttgtttccag
    34321 cctgttgttg gagcaactgc tttagctggt tctactgcta catctgttcc ttggttagat
    34381 gtaacagata caggatacga aggaatagat gattgctcag gaacaacaac tttttcaggt
    34441 tctctcgtcc ctctccttat acgtcttttt accatctctt tagtaatttg acgagaagta
    34501 gtttcttcaa ttgttccatc acgttcatct acagcataga ttgtagtaag agtaatttta
    34561 ccaatttctc ctacttcttg acctttatca agagttgggt catcgagata ttctgtttcg
    34621 attggaattt cttggacaag aacttggggc ttggttcctt ttttaacaac tcttgtttga
    34681 gagtcttctt tttgacttaa agtactctca gttacttgtc cactctttcc atctacatca
    34741 taagttatcg ttgtaactgt tttcccattc tttcctagag taatctcttg ctcctgtcct
    34801 gcagaaaggt cattgtctgc ttcatattta gtagtaaatg gaacaagaac ttcttcaacc
    34861 ttgcttttag ctggaacttt gataactgta tccgtggctt cttttctatc aacagtaacc
    34921 ttttcggtaa catgaccagt ctctggatta acatcgtagg tccttgtcgt agttacatag
    34981 ccatcctctc catcaattgt aacaggattt tcactacggt cttttgtttc atctttttca
    35041 taacgaattc gcgtacttga aattttcttg gttactacct taggtttagt cgctactttt
    35101 acaataatac tcccattgtc agcgtcatca tactctattc cctcttcttt atctctagta
    35161 tcatctctga catattgaat cccatcagca gcatgaacaa aacttgtatt cagattcctc
    35221 ctaaaaataa agttagcccg attaccgcag aaccaaaaat ctttccgagt ttacgtaatg
    35281 catagcgctt attagtatta gattttgcca ttacatccta cttctagtat agcatctttt
    35341 ctatcaaacg ttaaacagta tactttatat atcagataga cttagaatga tatattgatt
    35401 attgaactaa cactttaact atatcgtaat caatctcata tataaaggat tgcagacatc
    35461 ttatctaaat acatgctaat atatttagat acaaacattc caacttgata attttcactc
    35521 atctttcatc attccttata caactatgca gtataaatag aatagttttc tcatcagaat
    35581 gagactattt taatattaga taatttgata gaaaaaaaca taaataaaat tggttgaatt
    35641 taattcccta actcgataga agattctatt ttaaatttaa caacagctag gattacacta
    35701 taaaaagcac attaccacct gttcgactgg agaatctagt cgattagctc cctcttagtt
    35761 acaagcttaa agcgattttt taactaatac taaaccagat taaagaagga actagaacat
    35821 ctgtcttgta ctaatcaata tgctatttta aaattgcaaa taaacttgga atgctaatta
    35881 ttatatttac aataaatagt tgacttcgat agaaacagaa aatagaattc aacattcttc
    35941 cctacttata ccataataaa taagatccgc aagatagcct tttctctcta caccattaac
    36001 aatggtttgt agataggaca ttccagcctt ttccatgaca cgacctgaag ctgggttgag
    36061 actggcataa cgtgctctga ccttttgaaa acctgcttga gtaaaacaaa agtccaagac
    36121 agctttcaag gcctctgtca tcataccatg tccccagtaa gccttgccta gcacatagcc
    36181 gatttcacag cttaaatcag cctcgtctat cttaacgatg ctgatatctc ctatcacttg
    36241 ctctgggttt tcttttagac aaatggccca tttataatag ttgagattag tataggaagc
    36301 aacccaattg cgaatcgagt ttcgagtgat ttcgacatca ggatggggat cccaggtaac
    36361 ataggtcaga ttctcagcgg atgaagccca attttgaaac atggcttctg catcactctc
    36421 cacaaatctt cttaaaatca aacgttctgt ctgtaatatt tgcgtaccga tagatttcat
    36481 gatgctacct cacttcctta tttctatgct cgtagtaaaa agactcaact cagtaacagc
    36541 tagaaaacga gtttgtcttc taatttcttg acgcagttgc tgcatggttt gaaatgcgct
    36601 ctagcaatct ttttcaaacc tagtcatcgt tgcaggggta agacgatgaa atcgaactct
    36661 tcgagttacc gaatctgcct cattttctta tttctaaact cggggttcaa gatcccccgg
    36721 acctttttac tcccaaaagt catcaaatac ggtgatgggt aagtggcgtt tgtgttggcc
    36781 tttgtgccac cagttttcaa tggtcgcttg agcttctggg ctgattgttt tgccttctag
    36841 gtaatcgtca atctctgcat aggtgactcc aagtgcgact tcgtcagcta ggcctggttt
    36901 gtcttcttct aggtctgccg ttgggatttt ttcataaagg gctggctctg cgccaagttt
    36961 ctgcaagagt tgttttcctt ggcgtttatt gaggcggtaa agagggagaa tatccgcacc
    37021 gccgtcacca aacttggtaa agaaacctgt gatattttcc gcggcgtggt ctgttccaat
    37081 gaccgctccg ctatgggaac cagcaagggc atactgagca atcatacggc aacgtgcctt
    37141 gatattcccc ttgttgaagt ctgaaacagg actacctgtc gcttcaactg cagctgtcat
    37201 ggcatcagct gattccttga tattcacaac caagctgaca tctggctgga tgaaggctag
    37261 ggctttttga gcatctgctt catcagcttg cactccgtat ggcaggcgga cagcgataaa
    37321 tttgtagcta tcgtctcccg tttcagctcg cagttcttcc atagctaatt gcgccaaacg
    37381 tcctgccaag gttgaatctt gtcccccaga aatccctagt acaaaggttt ttaggaaggg
    37441 atgttttttc agatatcttt ttaagaaatc aatagaacga cggatttctt cctgggcatc
    37501 aatcactggt ttgacaccca gctcttggat aatcgtttct tgcaaactca ttcttcttct
    37561 ccttcaccaa gggcttcctt gcgcatctta tcaatcaagt ccatcttatc ttgccataca
    37621 tcacgcgcca aatccactgg atagtgctgc ggattgagca cacgcttata ctcatcccac
    37681 aacttgtcaa attccttacg ggcataatcc tgaatgtcag tcaaactagg caagttgtaa
    37741 actaatatac cttctttgaa gatatccacc aagagaggaa cggcatcaaa attacgaacc
    37801 gtcttcttga tgtatgtata ggtcggatgg aacatcttga tttctgtcat gtcgctaata
    37861 tccacaccat cataagtgat gtagtcacct tctgacttgc ctttttcacg actggtaatg
    37921 cgccacacct gcttcttacc tggcgtcgac actttttccg cattattaga cagcttaatc
    37981 gtattgcgca tctgaccagt ttcatcttcg attgcaacaa tcttgtaaac cgccccaaga
    38041 gctggctggt cataggctgt aatcagcttg gtacccacgc cccagacatc aatcttggcc
    38101 ttttgcatct tgaggttgag gatagtattt tcgtccaaat cattagaagc ataaatctta
    38161 gcctctgtaa atccagcctc gtccagttgc tgacggactt tcttagaaat gtaggcaata
    38221 tccccagagt caatccgcac acccataaag ttaatctgat cacccagctc acgcgccacc
    38281 tgaatggcag ctggtacacc gatgcgaagg gtgtcatagg tatccacaag aaagacacaa
    38341 tttttgtggg tcgcagcgta agccttgaaa gcttcatagt cattgccata aacctgtacc
    38401 aaggcatggg catgggttcc caaaacagga atgtcaaaga gcttacccgc acgcacgttg
    38461 ctggttccat tggcgccacc aatcacagct gcgcgtgttc cccagatggc cgcatccatt
    38521 tcttgagccc gacgtgtccc aaactccatc aagggttcat cttcgataac cgaacgaata
    38581 cgagctgcct tcgtcgccac caaggtctgg tagttgacga tgttcaaaag agccgtttcg
    38641 accaactgac attgggctag aggtccttcc acctgcacaa tcggttcatt agcaaaaacc
    38701 aaatcccctt cttgggcaga acgaacggtc aactccaact tgaaattgcg aaggtaatcc
    38761 aagaacgccc catgataacc aagcgactcc aaataggcta tatcactatc tgaaaaacgc
    38821 aagtcttcaa gatagttcac aattctttcc aaacctgcaa aaaccgcata gccgttctta
    38881 aaaggctgtt ggcggaaata cacctcaaag accgccttct tattgtgaat cccttggtca
    38941 aagtaaacct gcatcatgtt gatctggtac aagtccgtgt gcaatgtcaa actatcatct
    39001 ggatacatac ttttcctact tccttagcta gaaacccatg aaaattttca agaactttca
    39061 tgtattccaa taaattagta ctattatatc acattttagc tggattgaga aaagagtaac
    39121 aagctattct ccactctcca attcatccat atcttgttca aattttttct gagcccattc
    39181 gccatagctc ttaagaccaa gattgccaat aaagacccac ggaaggtaaa tgacataagt
    39241 aatgacccaa gcagacaggt atttaaaatt caaaggattg tgctgataaa tttctatgtt
    39301 gaattgataa ttctgcaaca tcaaaagagc cgtaatagcc aaggttagga aaaaacaacc
    39361 caaaatcgta aaatgaaaac gactatagta ggtcactccc agataacggg cacgattgaa
    39421 aaagtaaaat gtccctatga tgataacgat tagcagcata ttagaattaa aaaggcttgg
    39481 tgctaatact gaaatgatat aagataggag cgacaaagca atgcagatat agaaactttc
    39541 agagcccgct ttattgaaca gttgttcttc tctttcgtct agtaattgat aataataaaa
    39601 tctatttttc atcttcttcc tcccaaaata gttggtctag ggttttccct aaacatctgc
    39661 aaatagactg gcagagcgag agactgggat tgtattttcc cgcctctatc aaaccaatag
    39721 tctggcgtgt caccccgaca gcctctgcca gttgaccttg tgttaaatca cgctctaccc
    39781 gagctaattt taattttaaa tttttagcca ccttcgtcct ccttatagtt ttaatactca
    39841 tctactctta aaaaatccaa aaccaacaca agctatcagc tatttattat aaccccatta
    39901 atttgcactc cagtattatc ttcagccgaa aatcagtatt ttaggttgtt tgaaataaac
    39961 ttcctagttt actcttttat ttttatttag tattagcttt agtaggatct tttaaacgag
    40021 tttttattgc ttatatttct tgtttagttt agttggtttc atatcactat tatataatgc
    40081 ttttggaaat gagcctagta taagtcaaaa acgtgttgaa tagtgaaagc aggagcatac
    40141 caagatgact gattttttac tgtattttag gtatgcaaaa taatactaaa tgaaactaaa
    40201 atgaatactt cttgcttttc ttgagagtga aaaagtacaa taaaatgatt gtagtgatta
    40261 gcacaagata ctgactaata gacatcgtat ttgaagccac aaatacaggt aaagaataaa
    40321 aaggaagaag ttcaattgct ttgataaaca aatcattact agtattcatc atcgtattta
    40381 atatattagg gataaagagt agtaaagcta ctaaaatacc aaataccaag ccacttttca
    40441 atttgtataa atagaaaatg taagataata gaaaataaaa caggactaac aaaattgtat
    40501 tgactacaat agctactata aaatctaatc ctaaatcacc tggaataccc aatttactta
    40561 ctatgactag taacacaatg ccattcaaag cataaataat ggaaactgag atggcatata
    40621 gaaaattaga caagacgtaa atcatccgat tcttctgttg attataaaac aaacttaccg
    40681 tattgtggga aaaatctcta ctaatgactc gattagcatg tataacagcc attaacatac
    40741 cgagcatagc ataaaagttt gaaatatgct taataccaag cgatgtccct tgagtcttta
    40801 gaataaagaa tgtaagcaat atcggcggta taaacgagat aagcaaactg agatatatta
    40861 cgcctgatga atataaattt cttatatttt ccttaagaaa attaaattta tttaatttca
    40921 tgattataac cttcctttat tttgaacgat ttagataaat atctttaagc gtctcttttt
    40981 tagtttcaaa atcaactact ttaatagagt tttcgttaaa aaatttaaaa agctcactac
    41041 tttgaatatt cccagacata gtaatgctca gtccctcttc ctgaacaata tccccaaatt
    41101 cttgtttggt aatgaaaatg tctctatctg tagctgatga aaaagctatc tcaaacaaga
    41161 aattatgact atcttttcct actttttgaa atgtcaaaag cccgttctcc aagaaaagaa
    41221 ccctctcaca aatttcttca atatcttcta atttatgact cgatattaaa attcccacat
    41281 tttcatgtaa agctaaattt tttagaaccg ataaaactat ttgtgatgat tcaatatcta
    41341 aaccattagt cggttcatct aaaatcaata tatcaggttc cgtaacgaga gttagaagca
    41401 aagctaattt ttgttttgta cccaaagaat aggtctttac ttttttatta atagactgag
    41461 tcaaatctaa ctcttggatc aaacttctaa atatttcttg attgtagtca acaccatata
    41521 aatttgacaa atattttaaa ttctctaaac ctgttttaga taaaaataat tttggttctt
    41581 cgattaaata cccaacatta tcactgctta taatattacc tgaagtcggt tgattattct
    41641 gaacaagaat tttcatcaac gtactcttac caactccatt tctccctgct agaccaacaa
    41701 tttcaccctt gttaagtgca aaatttatat ctttgagaat gattgaatga ccataatgct
    41761 tacttacatt tataacttac attttttatt cctccattaa tattcatggt ttgctctttg
    41821 attcttattg agtttaaaaa gttgcgcctc tt
//
LOCUS       DAVKXA010000014        40160 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKXA010000014 DAVKXA010000000
VERSION     DAVKXA010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.014"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            692..2845
                     /locus_tag="VW883_000794"
     CDS             692..2845
                     /locus_tag="VW883_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0273968.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2858..4207
                     /locus_tag="VW883_000795"
     CDS             2858..4207
                     /locus_tag="VW883_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0273969.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4377..5084
                     /locus_tag="VW883_000796"
     CDS             4377..5084
                     /locus_tag="VW883_000796"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0273970.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5286..9011
                     /locus_tag="VW883_000797"
     CDS             5286..9011
                     /locus_tag="VW883_000797"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0273971.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9104..10546
                     /locus_tag="VW883_000798"
     CDS             9104..10546
                     /locus_tag="VW883_000798"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0273972.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10583..11605
                     /locus_tag="VW883_000799"
     CDS             10583..11605
                     /locus_tag="VW883_000799"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0273973.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11602..12147
                     /gene="purN"
                     /locus_tag="VW883_000800"
     CDS             11602..12147
                     /gene="purN"
                     /locus_tag="VW883_000800"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0273974.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12231..12740
                     /locus_tag="VW883_000801"
     CDS             12231..12740
                     /locus_tag="VW883_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0273975.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12765..14312
                     /gene="purH"
                     /locus_tag="VW883_000802"
     CDS             12765..14312
                     /gene="purH"
                     /locus_tag="VW883_000802"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0273976.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14434..15696
                     /gene="purD"
                     /locus_tag="VW883_000803"
     CDS             14434..15696
                     /gene="purD"
                     /locus_tag="VW883_000803"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0273977.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTIADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            16099..16587
                     /gene="purE"
                     /locus_tag="VW883_000804"
     CDS             16099..16587
                     /gene="purE"
                     /locus_tag="VW883_000804"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0273978.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16574..17665
                     /gene="purK"
                     /locus_tag="VW883_000805"
     CDS             16574..17665
                     /gene="purK"
                     /locus_tag="VW883_000805"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0273979.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSQDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            17675..17902
                     /locus_tag="VW883_000806"
     CDS             17675..17902
                     /locus_tag="VW883_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0273980.1"
                     /translation="MIQIIVNTFIEKYKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17965..19263
                     /gene="purB"
                     /locus_tag="VW883_000807"
     CDS             17965..19263
                     /gene="purB"
                     /locus_tag="VW883_000807"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0273981.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCNKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19318..23256)
                     /gene="strH"
                     /locus_tag="VW883_000808"
     CDS             complement(19318..23256)
                     /gene="strH"
                     /locus_tag="VW883_000808"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0273982.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGSPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAELVVAGLMSTLAAYGLTKRKED"
     gene            complement(23571..24287)
                     /locus_tag="VW883_000809"
     CDS             complement(23571..24287)
                     /locus_tag="VW883_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0273983.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24636..26423
                     /locus_tag="VW883_000810"
     CDS             24636..26423
                     /locus_tag="VW883_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0273984.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPCEGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKEENL"
     gene            26420..26896
                     /locus_tag="VW883_000811"
     CDS             26420..26896
                     /locus_tag="VW883_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0273985.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILGGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26924..27829
                     /locus_tag="VW883_000812"
     CDS             26924..27829
                     /locus_tag="VW883_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0273986.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27816..28631
                     /locus_tag="VW883_000813"
     CDS             27816..28631
                     /locus_tag="VW883_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0273987.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28638..29042
                     /locus_tag="VW883_000814"
     CDS             28638..29042
                     /locus_tag="VW883_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0273988.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29341..30507
                     /locus_tag="VW883_000815"
     CDS             29341..30507
                     /locus_tag="VW883_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0273989.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30623..31660
                     /locus_tag="VW883_000816"
     CDS             30623..31660
                     /locus_tag="VW883_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0273990.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31867..32721
                     /locus_tag="VW883_000817"
     CDS             31867..32721
                     /locus_tag="VW883_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0273991.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            32871..33128
                     /locus_tag="VW883_000818"
     CDS             32871..33128
                     /locus_tag="VW883_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0273992.1"
                     /translation="MTNSKYITCLKRSEGQLRGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33341..33424)
                     /locus_tag="VW883_000819"
                     /pseudo
     CDS             complement(33341..33424)
                     /locus_tag="VW883_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
     gene            complement(33458..33550)
                     /locus_tag="VW883_000820"
                     /pseudo
     CDS             complement(33458..33550)
                     /locus_tag="VW883_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33586..33882)
                     /locus_tag="VW883_000821"
                     /pseudo
     CDS             complement(33586..33882)
                     /locus_tag="VW883_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(33872..34033)
                     /locus_tag="VW883_000822"
     CDS             complement(33872..34033)
                     /locus_tag="VW883_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0273993.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            34103..34867
                     /locus_tag="VW883_000823"
     CDS             34103..34867
                     /locus_tag="VW883_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0273994.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(35101..35259)
                     /locus_tag="VW883_000824"
     CDS             complement(35101..35259)
                     /locus_tag="VW883_000824"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0273995.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            35477..36856
                     /locus_tag="VW883_000825"
     CDS             35477..36856
                     /locus_tag="VW883_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0273996.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36870..37535
                     /locus_tag="VW883_000826"
     CDS             36870..37535
                     /locus_tag="VW883_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0273997.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37649..37744
                     /locus_tag="VW883_000827"
                     /pseudo
     CDS             37649..37744
                     /locus_tag="VW883_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            37935..38474
                     /locus_tag="VW883_000828"
     CDS             37935..38474
                     /locus_tag="VW883_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0273998.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            38541..38951
                     /locus_tag="VW883_000829"
     CDS             38541..38951
                     /locus_tag="VW883_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0273999.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLY
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39067..>40160
                     /gene="pavB"
                     /locus_tag="VW883_000830"
     CDS             39067..>40160
                     /gene="pavB"
                     /locus_tag="VW883_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0274000.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNG"
BASE COUNT        11062 a         7800 c         9369 g        11929 t
ORIGIN      
        1 tctgttgttt tcacatttat agcaactctt attgaatatg gattttctct ctttctgatt
       61 acattatttt ttgataagaa taagaggaac tttggagata ttcttttatc taaaaatata
      121 accttaagtt ttagcatttt actttgttat ttatttaatc catcggatat aaagtttgcc
      181 tatttcagcg tattgacagt attactaatt gggataacaa attatgcgag atttaaaaat
      241 ttaagattga cagtagtgtt ttctgtacca tttttattta atgctataat gtctattata
      301 aatagttttt agaaatacta aaattttttt ctttacttaa taatgatatg aaatcatttc
      361 ggttttgtta acttgtaatt cttatatttt ctaggtagaa cgtttgttct gcctattttt
      421 ttatccaaaa agtgcagttg ggagggagat aggctcattt gggaaggaag tccagttttt
      481 gtttagtgat tggggtaaga tagttgttat cagatgagtt tatactcttc gaaaatcaaa
      541 ttcaaaccac gtcaacgtcg ccttgccgta tatatgtgac tgacttcgtc agtcctatct
      601 acaacctcaa aacagtgttt tgagcagcct gcggctagtt tcctagtttg ctctttgatt
      661 ttcattgagt attagggaaa aggagatgaa tatgaaattt gggaaacgtc actatcgtcc
      721 gcaagtggat cagatggact gcggtgtagc ttcattagcc atggtttttg gctactatgg
      781 tagttattat tttttggctc acttgcgaga attggctaag acgaccatgg atgggacgac
      841 ggctttgggc ttggtcaagg tggcagagga gattggtttt gagacgcgag ccattaaggc
      901 ggatatgacg ctttttgact tgccggattt gacttttcct tttgttgccc atgtgcttaa
      961 ggaagggaaa ttgctccact actatgtggt gactgggcag gataaggata gcattcatat
     1021 tgccgatcca gatcccgggg tgaagttgac taaactgcca cgtgagcgtt ttgaggaaga
     1081 atggacagga gtgactcttt ttatggcacc tagtccagac tataagcctt ataaggaaca
     1141 aaaaaatggt ctgctctctt ttatccctat attagtgaag cagcgtggct tgattgccaa
     1201 tatcgttttg gcaacactct tggtaaccgg gattaacatt gtgggttctt attatctgca
     1261 gtctatcatt gatacctatg tgccagatca gatgcgttcg acactaggga ttatttctat
     1321 tgggctagtc atcgtctaca tcctccagca aatcttgtct tacgctcagg agtatctctt
     1381 gcttgttttg gggcaacgct tgtcgattga cgtgattttg tcctatatca agcatgtttt
     1441 tcacctccct atgtccttct ttgcgacacg caggacaggg gagatcgtgt ctcgttttac
     1501 agatgctaac agtatcatcg atgcgctggc ttcgaccatc ctttcgattt tcctagatgt
     1561 gtcaacggtt gtcattattt cccttgttct attttcacaa aataccaatc tctttttcat
     1621 gactttattg gcgcttccta tctacacagt gattatcttt gcctttatga agccgtttga
     1681 aaagatgaat cgggatacca tggaagccaa tgcggttctg tcttcttcta tcattgagga
     1741 catcaacggt attgagacta tcaagtcctt gaccagtgaa agtcagcgtt accaaaaaat
     1801 tgacaaggaa tttgtggatt atctgaagaa atcctttacc tatagtcgag cagagagtca
     1861 gcaaaaggct ctgaaaaagg ttgcccatct cttgcttaat gtcggcattc tctggatggg
     1921 ggctgttctg gtcatggatg gcaagatgag tttggggcag ttgattacct ataatacctt
     1981 gctggtttac tttaccaatc ctttggaaaa tatcatcaat ctgcaaacca agcttcagac
     2041 agcgcaggtt gccaataacc gtctaaatga agtgtatcta gtagcttctg agtttgagga
     2101 gaagaaaaca gttgaggatt tgagcttgat gaagggagat atgaccttca agcaggttca
     2161 ttacaagtat ggctatggtc gagacgtctt gtcggatatc aatttaaccg ttccccaagg
     2221 gtctaaggtg gcttttgtgg ggatttcagg gtcaggtaag acgactttgg ccaagatgat
     2281 ggttaatttt tacgacccaa gtcaagggga gattagtctg ggtggtgtca atctcaatca
     2341 gattgataaa aaagccctgc gccagtacat caactatctg cctcaacagc cctatgtctt
     2401 taacggaacg attttggaga atcttctttt gggagccaag gaggggacga cacaggaaga
     2461 tatcttacgg gcggtcgaat tggcagagat tcgagaggat atcgagcgca tgccactgaa
     2521 ttatcagaca gaattgactt cggatggggc agggatttca ggtggtcaac gtcagagaat
     2581 cgctttggcg cgtgctctct tgacagatgc gccggtcttg attttggatg aggcgactag
     2641 cagtttggat attttgacag agaagcggat tgtcgataat ctcattgctt tggacaagac
     2701 cttgattttc attgctcacc gcttgactat tgctgagcgg acagagaagg tggttgtctt
     2761 ggatcagggc aagattgtcg aagaaggaaa gcatgctgat ttgcttgcac agggtggctt
     2821 ttacgcccat ttggtcaata gctagaaaga ggagaggatg aaaccagaat ttttagaaag
     2881 tgcggagttt tataatcgtc gttaccataa tttttccagt agtgtgattg tacccatggc
     2941 ccttctgctc gtgtttttac ttggctttgc aactgttgca gaaaaggaga tgagtttgtc
     3001 cactagagct actgtcgaac ctagtcgtat ccttgcaaat atccagtcaa ctagcaacaa
     3061 tcgtattctt gtcaatcatt tggaagaaaa taagctggtt aagaaggggg atcttttggt
     3121 tcaataccaa gaaggggcag agggtgtcca agcggagtcc tatgccagtc agttggacat
     3181 gctaaaggat caaaaaaagc aattggagta tctgcaaaag agcctgcaag aaggggagaa
     3241 ccactttcca gaggaggata agtttggcta ccaagccacc tttcgcgact acatcagtca
     3301 agcaggcagt cttagggcta gtacatcgca acaaaatgag accatcgcgt cccagaatgc
     3361 agcagctagc caaacccaag ccgaaatcgg caacctcatc agtcaaacag aggctaaaat
     3421 tcgcgattac cagacagcta agtcagctat ggaaacaggt gcttccttgg ccagtcagaa
     3481 tctagcctac tctctttacc agtcctacaa gtctcagggc gaggaaaatc cccaaactaa
     3541 ggttcaggca gttgcacagg ttgaagcaca gatttctcag ttagaatcta gtcttgctac
     3601 ttaccgtgtc cagtatgcag gttcaggtac ccagcaagcc tatgcgtcag ggttaagcag
     3661 tcaattggaa tcccttaaat cccaacattt ggcaaaggtt ggtcaggaat tgacccttct
     3721 agcccagaaa atcttggagg cagagtcagg taagaaggta cagggaaatc ttttagacaa
     3781 ggggaaaatt acggcgagtg aggatggggt gcttcatctt aatcctgaga ccagtgattc
     3841 tagcatggtt gcagaaggtg ccctactagc ccaactttat ccatctttgg aaagagaagg
     3901 gaaagccaaa ctcacagcct atctaagttc aaaagatgta gcaagaatca aggtcggtga
     3961 ttctgttcgc tatactacga ctcatgatgc cgggaatcaa cttttcctag attcaactat
     4021 tacaagtatt gatgcgacag ctactaagac tgagaaaggg aatttcttta aaatcgaggc
     4081 ggagactaat ctaacttcgg agcaggctga aaaacttagg tacggggtgg aaggccgctt
     4141 gcagatgatt acgggcaaga aaagttatct acgttattat ttggatcaat ttttgaacaa
     4201 agagtaatgt tcgtgttttt agagttaaat aatttttaaa ctgtgagaaa gattcttctt
     4261 gcagtttttt ctttacaatt tttgaaaaac atctactatt tattcggtta aattcttgtg
     4321 ttttttggtt ttttgtggta aaatttgctc aagtaatacg aaaggcgaac tttaaaatgt
     4381 caaaacaatt gatctattcg ggaaaagcta aagatatcta tacaactgag gatgaaaatc
     4441 ttattatttc aacttacaag gaccaggcga ctgctttcaa cggtgtcaag aaggagcaga
     4501 ttgcaggtaa gggagtcttg aataatcaga tctcatcttt tatttttgag aaattaaatg
     4561 cggctggtgt ggcgactcac tttgtggaga aactttcaga cacggaacaa ctcaataaaa
     4621 aggttaagat tattcctttg gaagtcgtgc tccgcaacta tactgctggt tccttttcaa
     4681 aacgttttgg tgtggatgag ggaatcgcct tggagactcc gattgtcgaa ttttactaca
     4741 aaaatgatga tttggatgat ccatttatca atgatgagca tgtgaaattc ctacagattg
     4801 cgggtgacca gcagattgcc tacttgaagg aagaaacgcg tcgtatcaat gaactattga
     4861 aagtctggtt tgctgagatt gggcttaaat tgattgactt taagctagag ttcggttttg
     4921 acaaggatgg caagattatc ttggcagacg aattttcacc agataactgc cgcttgtggg
     4981 acgctgatgg caaccacatg gataaggatg ttttccgtag aggattggga gaactaaccg
     5041 acgtttatga gattgtttgg gaaaagttgc aggaattgaa ataatctgtt tgcaacggaa
     5101 aaccttcgtc tctcaactaa aaggactcag gctgaaaagg tcccccagac cttttcactc
     5161 tgtagagaac taggtgaact aacagatgtt tacgaaattg tctgggaaaa gttgcagggt
     5221 ttaaaataac aacctcaagg ctgtttggga atattgcaag agctgaaata aaggaataag
     5281 aattgatgga taaacgtatt tttgttgaaa aaaaggctga ttttcaggtc aagtcagaga
     5341 gtttggttag agagctccag cacaacttgg gactgtcaag cttgaaaagt attcgtattg
     5401 tgcaagtata tgatgtattt gacttggctg aggacttgtt tgcacctgca gagaagcaca
     5461 ttttctctga gcagggaacc gaccatgttt tagatgaagt atctgtgcag gcggatcttg
     5521 ctaactatgc tttctttgcc attgaaagtc tgccagggca gtttgaccag cgtgcagctt
     5581 cgtcacagga agccttgctt ttgttgggaa gttcgagtga cgtgacagtc aacacagccc
     5641 aactttactt ggtgaataaa gatattgatg cgactgagtt ggaagctgtc aaaaactacc
     5701 tgctcaatcc agttgattct cgtttcaagg atatcacgac agggattgcc aagcaggagt
     5761 tttcagagtc agacaagacc attccaaaat tgactttctt tgaaagctat acagcagaag
     5821 actttgctcg ctacaaggcc gagcaaggga tggccatgga agtggatgat ttgctcttta
     5881 tccaagacta ctttaagtca atcgggcgcg tgccaactga gactgaactc aaggttttgg
     5941 acacttactg gtctgaccac tgccgtcata cgacttttga gacagagttg aaacacatcg
     6001 acttttcagc ttctaaattt caaaagcaat tgcagtcaac ctatgacaag tatattgcca
     6061 tgcgcgagga gttaggtcgg tctgaaaaac cacaaacctt gatggatatg gcgactattt
     6121 tcggtcgtta tgagcgtgct aacggacgat tggatgatat ggaagtctct gacgaaatca
     6181 atgcctgctc agttgaaatt gaagtggatg ttgatggtgt caaggaacct tggctcctca
     6241 tgtttaaaaa tgaaacccac aaccatccaa cagaaattga gccatttggt ggagcggcta
     6301 cctgtatcgg tggagctatt cgtgatccgt tgtcaggccg ttcctatgtt taccaagcca
     6361 tgcgtatttc aggtgctggt gatattacag caccgatttc ggaaactcgt gctgggaaat
     6421 tgccacaaca agtcatttct aaaacagcag ctcatggtta ttcttcatat ggtaaccaga
     6481 ttgggcttgc cacaacctac gttcgtgaat acttccaccc aggctttgta gctaaacgta
     6541 tggaacttgg tgccgttgtt ggtgcggctc ccaagggcaa tgttgtccgt gaaaaacctg
     6601 aagcaggtga tgtgatcatc cttctcggag gcaaaacagg tcgtgatggt gtcggtggtg
     6661 cgacgggctc ttctaaggtt caaacagttg agtctgtaga gactgctggt gctgaggttc
     6721 aaaaaggaaa tgccatcgaa gaacgcaaga ttcagcgcct cttccgtaat ggcaatgtca
     6781 ctcgtctgat caagaagtcc aatgactttg gggcaggcgg cgtctgtgtg gctatcggtg
     6841 aattggcaga cggtcttgaa atcgacctca acaaggtgcc tcttaaatac cagggcttga
     6901 atggtacaga aattgccatc tctgaatcac aagaacggat ggcggtcgtg gttcgtcctg
     6961 aagatgtgga tgccttcgtt gccgaatgta acaaagaaaa tattgatgct gttgtggtgg
     7021 cgacagtaac tgaaaaacca aatcttgtca tgcactggaa tggtgagaca atcgttgact
     7081 tggagcgtcg tttccttgac accaatggtg tgcgcgtggt tgtcgatgcc aaagttgtgg
     7141 acaaggatgt caaactccca gaagagcgtc aaacatctgc tgaaacactg gaatcagata
     7201 cccttacggt tctatctgac ctcaaccatg caagtcaaaa aggattacag actgtctttg
     7261 actgctctgt tggacgctca acggttaatc acccacttgg tggtcgttac caactcacac
     7321 caactgaggc atctgtgcag aaattgccag ttcaacacgg tgtgactcat actgcgtcgg
     7381 tcattgctca aggtttcaac ccatatgtag ctgaatggtc tccataccac ggtgctgctt
     7441 acgcggttat cgaagcaact gctcgtttgg tggctgctgg tgccaactgg tctaaggctc
     7501 gtttctctta ccaagaatat ttcgagcgga tggacaagca agcagagcgt tttggtcagc
     7561 cagtagccgc ccttctaggc tctattgaag ctcagattca acttggcttg ccatctatcg
     7621 gtggtaagga ctccatgtct ggtacctttg aagaattgac cgttccgcca accttggttg
     7681 cctttggggt gacgacggca gatagccgta aggtgctctc tccagaattt aaagctgttg
     7741 gggaaaatat ctactacatc ccaggtcaag ccctctctgc agagattgat tttgacttga
     7801 ttaagaaaaa ttttgctcag tttgaagcaa gccaagctga ccataaagtg acatctgcat
     7861 cagctgtcaa atacggtggt gtagttgaaa gtttggctct tgctaccttt ggaaactata
     7921 ttggtgcaga ggtgaccttg cctgaactta aaacagcttt gacagctcaa ttaggcggct
     7981 ttgtcttcac atctcctgaa gaaattgctg gagtagagaa gattggacaa acgaaagcag
     8041 actttacact gactgtcaac ggtgtgaagc tagatggaca caagcttgac agtgcatttc
     8101 aagggacatt ggaagaagtt tacccaacag aatttaccca agcgaaagaa ctagaagaag
     8161 taccagctgt ggcatcagat gttgtgatta aagccaaaga aaaggttgaa aaacctgtgg
     8221 tttacatccc agtctttcca ggaaccaact cagaatacga ttcagctaag gccttcgaaa
     8281 aagaaggtgc agaggtcaat ttggtgccat tcgtgacctt gaatgaagaa gctattgtca
     8341 agtcagttga aactatggtt gacaatatcg acaagactaa tattctcttc tttgccggtg
     8401 gattctcggc tgcggatgaa ccagatggtt cagctaagtt tatcgtcaat atcctgctta
     8461 atgaaaaagt gcgtgtggct attgatagct ttatcgcccg tggtggcttg attatcggta
     8521 tttgtaatgg attccaagcc ttagtcaaat cgggtctcct accatacgga aactttgaag
     8581 atgctaacag tactagtcca accctcttct acaatgatgc caaccaacac gtggccaaga
     8641 tggtggaaac tcgcattgcc aataccaact caccatggtt ggctggtgtg caagtgggcg
     8701 atatccacgc tattcctgtt tcgcacggtg aagggaagtt tgtcgtgacg gctgaggaat
     8761 ttgcagagct ccgtgacaat ggacaaattt tcagccaata cgttgacttt aacggtaaac
     8821 caagtatgga ttctaagtac aatccgaatg gttctgtcca tgccatcgaa ggaattacca
     8881 gcaagaatgg tcaaatcatc ggtaagatgg gccactcaga acgttatgag gatggtcttt
     8941 tccaaaatat cccaggcaat aaagaccaac acctgttcgc atcagcggtt aaacatttca
     9001 ctggaaaata agacttacag attttctaat agatagtatc agtaatgtaa aagtcatgta
     9061 aatctagctc ttgatgatta caaatgaaaa ttaggtataa aaaatgacat acgaagtaaa
     9121 atctcttaat gaagaatgtg gtgttttcgg tatttgggga catccagatg ctgctaagtt
     9181 gacctatttt ggactccaca gtcttcaaca ccgtggtcag gagggggcag gaatcctctc
     9241 caacgatcaa ggacaactga agcgccatcg tgacatgggg cttttatcag aagttttcag
     9301 aaatccagct aatttggata aattgacagg agctggtgcg attgggcatg tgcgttatgc
     9361 gactgctggc gaagcttctg tagataacat ccagcccttc ctcttccgtt ttcacgatat
     9421 gcagtttggc ttggctcata atggaaatct gaccaatgca gcctctctca agaaagaact
     9481 ggaacaaaga ggagcaattt tcagcgcgac ttcggactct gaaatcttgg ctcacctcat
     9541 tcgtcgcagt cataatccta gcctgatggg caaaatcaag gaagcgctca gccttgtcaa
     9601 aggtggtttt gcctatatct tgctgtttga ggacaagttg attgcggctc ttgaccctaa
     9661 tggctttcgt ccgctttcta tcgggaaaat ggccaacgga gcggtggttg tttcctctga
     9721 aacctgtgct tttgaggtca ttggtgccga gtggattcgt gatttgaagc caggtgagat
     9781 tgtgatcatt gatgacgagg gcattcagta tgacagctat acagatgata cccagttggc
     9841 gatttgttct atggagtata tctactttgc ccgccctgat tctaatatcc acggtgtcaa
     9901 tgtccatacg gcacgtaaga gaatgggagc gcaattggcg cgagaattta agcatgaggc
     9961 agatattgta gttggtgtgc ccaattcttc cctaagcgcg gctatgggat ttgcggaaga
    10021 atcaggctta ccaaatgaaa tgggtctgat caaaaaccaa tacacccagc gaacttttat
    10081 ccaaccgact caagaattgc gggagcaagg agtgcggatg aaactgtctg ctgtttcggg
    10141 tgttgtcaaa ggcaaacgtg tggtcatggt ggatgattcc attgtacgtg gaacaacctc
    10201 tcgtcgtatc gttcagctct tgaaagaagc gggtgcgact gaggttcacg ttgccattgg
    10261 aagtcctgca ctagcgtatc catgtttcta cgggattgat atccagaccc gtcaggagct
    10321 gattgcagcc aatcatacgg tcgaagaaac tcgccaaatc attggtgcgg acagtctgac
    10381 ttatctttca attgatggct tgattgagtc gattggtatc gaaacagatg cgccgaacgg
    10441 tggtctctgt gtcgcttact ttgacggtga ctacccaacg cctctctatg actacgaaga
    10501 agactatcgt agaagtttgg aagaaaagac cagtttttac aagtaggcga cagattctcc
    10561 attaaagaaa aggaaaaaac aaatgacaaa taaaaatgca tatgcccagt cgggtgtgga
    10621 tgttgaagcg ggttatgaag ttgttgaacg gattaaaaag cacgtggccc gtacggagcg
    10681 tgcaggtgtc atgggagctc ttggtggctt tggtggtatg tttgaccttt ccaagactgg
    10741 ggttaaagaa cccgtcttga tttcagggac tgacggtgtc ggaaccaagc tcatgttggc
    10801 tatcaagtac gacaagcacg ataccatcgg gcaggactgt gtggccatgt gtgtcaacga
    10861 catcattgct gcaggtgcgg aacccctcta ttttctcgac tacgtagcga cagggaagaa
    10921 tgaaccagct aagctagaac aagtggttgc tggtgtggca gaaggttgtg tgcaggctgg
    10981 tgctgccctc atcggtgggg aaacggctga aatgccgggc atgtacggcg aagacgacta
    11041 tgacttggct ggttttgcgg tcggtgtggc tgaaaaatct caaatcattg acggttcaaa
    11101 ggtggtagag ggagatgttc ttctcggact tgcttcaagt gggattcact caaatggtta
    11161 ctctttggtt cgtcgtgtct ttgcggatta cacaggtgag gaagtcctac cagaattgga
    11221 aggcaagaaa cttaaggaag ttctacttga gccgactcgt atctatgtca aggctgtctt
    11281 gccgctcatc aaagaagagt tggtcaacgg cattgcccac atcacaggtg gtggctttat
    11341 cgaaaatgtc cctcgtatgt ttgcagatga cctagctgct gaaattgatg aaagcaaagt
    11401 tccagtgctt ccaattttca aagcccttga aaaatatggt cagattaaac acgaagaaat
    11461 gtttgaaatc ttcaatatgg gtgtgggact tatgttggcg gtcagccctg aaaatgtaga
    11521 gcgtgtaaaa gaattgttgg atgaagcagt ctatgaaatt ggtcgcatcg tcaagaaaga
    11581 aaacgaaagt gtcattatca aatgaaaaaa atagcggttt ttgcctctgg taatggctca
    11641 aattttcagg tgattgccga agaatttcca gtggagtttg tcttttcaga ccatcgtgat
    11701 gcctatgtgc ttgagcgtgc aaagcagctc ggcgttctgt cctatgcttt tgaactcaag
    11761 gagtttgaga gcaagacaga ctacgaagca gcccttgtcg aactcttgga agaacaccag
    11821 attgacttgg tttgcctagc aggctacatg aaaatcgttg gaccaacctt attgtcggct
    11881 tatgaaggtc ggattgtcaa cattcatcca gcctacttgc cagaatttcc aggagctcat
    11941 gggattgagg atgcttggaa tgctggcgtg ggtcagtctg gtgtgaccat tcactgggtg
    12001 gattcgggtg tggatacagg ccaggtcatc aaacaggttc gtgtgccacg actagctgat
    12061 gataccattg acagatttga agctcgcatc catgaagcag agtacaggtt gtatccggaa
    12121 gtagtgaagg ctctatttac agattgactt tttgatgatt catatgatat ctttgatttt
    12181 aaattggagt cagtgtttgt tgaagacggc ttcaaacgga ggtatttgta atgttagaat
    12241 ctaaaaaaac aactcgatat gtattttatg tctatctgat gttattaact tggggaatct
    12301 tatttaagtt tgaaacaaat cctgaattta tagcattttt cttagctcca aggtatatca
    12361 attggattcc attttcagaa ccactaatag tcgatggaaa aattgttttt gctgaaatgt
    12421 tatttaatct gatttccttt attccattag gtgtttgttt ccctttgata aaaactaatt
    12481 tatctagttt aagaatagtc gggacaggtt tcttgattag tttattgttt gagtgcttac
    12541 agtatatttt agcaataggt ataacagata taacggattt gactttaaat acgctaggtg
    12601 tctgtgtagg cttactgatt tatcaaattt ttataagagt gttcaaatca cagactagaa
    12661 aatggatcaa tatcttaggt atgcttagcc ttggttttgc ttatcttgtt ttactgttac
    12721 tgcatttaat tggtgtttaa ctaatgatta aaaaggagaa tataatgact aaacgcgtct
    12781 taatcagcgt ctcagacaaa gcgggcattg ttgaatttgc ccaagaactc aaaaaacttg
    12841 gttgggagat tatctcaaca ggtggaacta aggttgccct tgataatgct ggggtggata
    12901 ccattgctat cgatgatgtg actggtttcc cagaaatgat ggacggtcgt gtgaagaccc
    12961 tccacccaaa tatccacgga gggcttctcg ctcgtcgtga cttggatagc cacttggaag
    13021 cggctaagga caacaagatt gagctcattg accttgtggt ggtcaacctt tacccattta
    13081 aggaaactat ccttaaacca gatgtgactt atgctgatgc agttgaaaat atcgatattg
    13141 gtgggccgtc tatgcttcgt tcagcagcga aaaatcatgc cagtgttaca gttgtggtag
    13201 atcctgctga ctacgctgtg gttttggacg aattggcagc aaacggcgaa acctcttatg
    13261 aaactcgcca acgtttagca gccaaagtat ttcgtcacac agcggcttat gacgccttga
    13321 ttgcagaata cttcacagct caagtgggtg aaagcaagcc tgaaaaactc actttgactt
    13381 atgacctcaa gcaaccaatg cgttacggtg agaatcctca acaagatgcg gacttttacc
    13441 agaaagcttt gcctacagac tactccattg cttcagccaa acagctcaac gggaaagaat
    13501 tgtcatttaa taatatccgt gatgcagatg ctgctatccg tatcatccgt gacttcaaag
    13561 atagtccaac cgttgtggct ctcaaacaca tgaatccatg tggaattggt caagctgatg
    13621 acatcgagac tgcttgggac tacgcttatg agtctgaccc agtatctatc tttggtggga
    13681 ttgtcgtcct caaccgtgag gtggatgctg cgacagctga gaagatgcac ggcgttttcc
    13741 tcgaaatcat cattgcacca agctatacgg atgaagcgct agccattttg atcaataaaa
    13801 agaaaaactt gcgtatcctt gccttgccat ttaatgctca agaggctagc gaagtggaag
    13861 cagaatacac aggtgtagtc ggtggacttc tcgtgcaaaa tcaagacgtg gtcaaggaaa
    13921 gcccagctga ctggcaagtg gtgaccaaac gtcagccaac cgagacagaa gcgactgctc
    13981 ttgagttcgc ttggaaggct atcaagtacg tcaaatcaaa tggtattatc gtgaccaacg
    14041 accacatgac acttggtgtt ggtccaggtc aaaccaaccg tgtggcttct gttcgccttg
    14101 ccattgacca agccaaagat cgtctggacg gggcggtcct tgcttcagat gccttcttcc
    14161 catttgcgga taacgtggaa gaaatcgcca aagcaggaat taaggccatc atccagcccg
    14221 gtggctctgt ccgtgaccaa gaatccatcg aagcagcgga taaatacggc ttgactatgg
    14281 tctttacagg tgtgagacat tttagacatt aagaagataa aagggaagaa aacagtttct
    14341 ttcctttttt ggcttaaaat gctaactgaa acaagattaa aacgaacttt tttgatataa
    14401 tgttggtaaa taattcgcaa aagaggttga ggaatgaaac tgcttgttgt cggttctggt
    14461 ggtcgtgagc atgcgattgc taaaaagtta cttgaatcaa aagacgtgga aaaagtcttt
    14521 gtagctcctg ggaatgatgg gatgactctg gatggtttgg aattggtaaa tatctctatt
    14581 tccgaacatt ctaaattgat tgacttcgca aagaccaatg atgttgcttg gacctttatc
    14641 ggtccagatg atgcccttgc tgctggtatc gtggatgatt ttaaccaagc tggacttaag
    14701 gcctttggtc cgactagggc tgcagcggag ctggagtggt ccaaggattt cgccaaggaa
    14761 atcatggtca aatacggcgt tccgacagca acatatggca cattttcaga tttcgaggaa
    14821 gccaaggcct atatcgaaaa gcatggtgcg cctatcgtag tcaaggcgga tggcttggca
    14881 cttgggaagg gtgtcgtcgt tgctgagacg gttgagcaag cggtcgaagc cgctcatgag
    14941 atgcttttgg acaataaatt tggtgactca ggtgcgcgcg tggttattga ggaattcctt
    15001 gaaggagagg aattttcact ctttgccttt gtcaatggtg ataagttcta catcatgcca
    15061 acggctcagg accacaaacg tgcctatgat ggcgacaaag ggcctaacac gggtggtatg
    15121 ggtgcctatg cgccagtccc acacttacca cagagtgtag ttgatacagc ggttgacacc
    15181 attgtcaagc cagttctaga aggggtgatt aaagaaggtc gcccttatct gggagttctt
    15241 tacgcagggc ttatcctgac agctgatgga ccgaaagtca ttgagttcaa cgctcggttc
    15301 ggagatccag aaactcagat tatcttgcct cgcttgacct ctgactttgc tcaaaatatc
    15361 acagatatcc tggatagcaa ggagccaaat atcatgtgga cggacaaggg tgtgactctg
    15421 ggtgtggttg tcgcatccaa gggctacccg ctagactatg aaaggggcgt tgagttgcca
    15481 gccaagacag aaggcgatgt catcacctac tatgcagggg ctaagtttgc ggaaaatagc
    15541 agagcactgc tctcaaacgg cggacgagtt tatatgctcg ttaccatagc agataccgtc
    15601 aaagaagccc aagccagcat ataccaagaa ctataccaac aaaaaataga aggactcttc
    15661 taccgaacag atatcggaag caaggcaatt aagtaaagat ataagaataa cgcgccgtag
    15721 tcgccaaaca cgataatggt cgtcgtggtg aaaagaccag aacagtgaat gttctggtca
    15781 gggggaaact tggagacctt aggctcaaag tttaggaatg aaaccgaagg tttgcttccg
    15841 cctccatcac ctaagaccat tatcaaaaag aaaaataaaa attcacaaaa tacgttaatg
    15901 atcgtatggt ttgcgagcgt tagcgagcta atatagaaca atcaccgccg ttgtgaaaga
    15961 acgattggat gataatccaa tcgttcaggg aaattggaag accttgggtt tccaatttag
    16021 gcatgagaca cctttggtgg ctgctgccgt ccctcacaag ctaaggtgat tgttgaaaaa
    16081 gaggaaaaag gagaagaaat gaaaccagta atttccatca tcatgggctc aaaatccgac
    16141 tgggcaacca tgcaaaaaac agcagaagtc ctagaccgct tcggtgtagc ctacgaaaag
    16201 aaagttgttt ccgcacaccg tacaccagac ctcatgttca aacatgcaga agaagcccgt
    16261 agtcgtggca tcaagatcat catcgcaggt gctggtggcg cagcgcattt gccaggcatg
    16321 gtagctgcca aaacaaccct tccagtcatt ggtgtgccag tcaagtctcg tgctcttagt
    16381 ggagtggatt cactctattc tatcgttcag atgccgggtg gggtgcctgt tgcgaccatg
    16441 gctatcggtg aagctggagc gactaacgca gctctctttg ccctccgtct cctctctgta
    16501 gaagataagt ccattgcgga tgcacttgcc aactttgctg aagaacaagg aaaaatcgca
    16561 gaggagtcgt caaatgagct catctaaaac aatcggaatt atcggtggcg gtcaactggg
    16621 tcagatgatg gccatttctg ctatctacat gggccacaag gttatcgcgc tggatcctgc
    16681 ggcggattgc ccggtctctc gtgtggcgga aatcattgtg gcaccttata acgatgtaga
    16741 cgccctccgt cagttggcag accgttgcga tgtcctcact tacgagtttg aaaatgtcga
    16801 cgctgacggt ttggatgccg ttatcaagga tggacaactc cctcaaggga cagacctgct
    16861 ccgcatttcg caaaatcgta tttttgaaaa ggactttttg tcaaacaagg ctcaagtcac
    16921 cgttgcacct tacaaggttg tgacctcaag ccaagatttg gcagatatcg acttgtcgaa
    16981 aaactatgtt ctcaagactg cgactggtgg ctacgatggt catggacaaa aggttattcg
    17041 ttcagaagca gacttggaag cagcctatgc gctagcagac tcagcagact gcgtcttgga
    17101 agaatttgtc aactttgacc ttgagatttc tgtcatcgtg tcaggaaatg gcaaggaggt
    17161 gacgtttttc ccagttcagg aaaatatcca ccgcaacaat atcctgtcta agaccattgt
    17221 accagcccgt atttctgaaa gtctagcaga caaggctaaa gctatggcag tgcgaatcgc
    17281 agaacaactc aacttgtctg gaactctctg tgtggaaatg tttgcgacag ctgatgacat
    17341 cattgtcaat gaaatcgccc cacgaccaca taactctggg cactattcta ttgaagcctg
    17401 tgatttctct cagtttgaca cccatattct gggtgttctc ggagcaccat taccagtcat
    17461 caaactccat gcgccagccg ttatgcttaa tgtcctcggt cagcatgtcg aggctgctga
    17521 aaaatatgtc acagaaaatc caagcgccca cctccacatg tatggtaaaa tagaagcaaa
    17581 gcataatcgt aagatgggac atgtgacttt gtttagtgat gtgccggata gtgtggaaga
    17641 gtttggggaa gggattgatt tttaggacaa gtctatgata caaattatcg ttaatacatt
    17701 tattgaaaag tataagactg gagcagttgt tgaagtgttg tatgccagtg ctgaccaaga
    17761 taaggtacaa gctaaatatg aagaactagc tgcacaatac cccgaaaatt atttagctat
    17821 ctatgatgta ccgctggata cggatttgaa tacactagat cattacccgt ctgtgtttat
    17881 tgaaaaagag gagtttgagt agaaatcttg gtttacctag atagcttatt cccaacagct
    17941 taagaagaaa ggaaaaatta acacatgatc aaccgttact ctcgccctga gatggcgaat
    18001 atttggagtg aagaaaataa ataccgtgct tggcttgagg tggaaatcct ctctgacgag
    18061 gcatgggctg agttggggga aatccctaag gaagatgtgg ctttgattcg caagaaggcg
    18121 gactttgaca tcgaccgtat tttggaaatt gagcaggaga cgcgccacga tgtggtggct
    18181 ttcacgcgtg cggtttctga gactcttggt gaagagcgca agtgggttca ctatgggtta
    18241 acttctaccg acgtggtgga tactgcttat ggttacctct acaagcaggc caacgacatc
    18301 atccgtcgtg accttgaaaa cttcactaat atcatcgctg acaaggccaa ggagcacaag
    18361 ttcaccatca tgatggggcg tactcatggt gtgcacgctg agccgacaac ttttggtctt
    18421 aaattggcaa cttggtatag cgaaatgaaa cgcaatatcg agcgtttcga gcatgcggct
    18481 gctggtgtag aagctggtaa gatttctggt gcggttggga actttgccaa tatcccacca
    18541 tttgtagagg agtatgtctg caacaagctt ggtatccgtg ctcaagaaat ctctacacaa
    18601 gtccttcctc gtgaccttca cgctgagtac tttgcagttc ttgccagcat tgcgacttca
    18661 atcgaacgta tggcgactga gattcgtggt ctacaaaaat ctgagcaacg cgaagtagaa
    18721 gagttctttg ctaaagggca aaaagggtct tcagcaatgc ctcacaaacg caacccaatc
    18781 ggttctgaaa atatgactgg tctggcgcgt gtcattcgtg gtcacatgat tacggcttat
    18841 gaaaacgtcg ctctctggca cgaacgcgat atttcccact catcagctga gcgtatcatc
    18901 acaccagata cgaccatttt gattgactac atgctcaacc gttttggaaa tatcgtcaag
    18961 aacttgacag tcttcccaga aaatatgatc cgaaacatga actcgacttt tggtcttatc
    19021 tttagccaac gggctatgtt gacattgatt gaaaaaggca tgacccgtga gcaagcctat
    19081 gacttggtgc aaccaaaaac agcctactct tgggacaacc aagtagactt taaaccactt
    19141 cttgaggcag attcagaagt aacatcacgt ctcactcaag aagaaatcga tgaaatcttc
    19201 aacccagttt attacaccaa acgagtggat gatatctttg aacgtcttgg actaggtgat
    19261 taattaaaaa ataaacagcg agcttcaatc tcgctgttta ttttttatcg aaaagactta
    19321 gtcttctttt cttttagtga gtccataggc tgctagtgtg gacatgagtc ctgcgactac
    19381 tagttctgca gaatcgtgag ttcctgtttc aggaagtttt ttctctgtta ccacaggagc
    19441 tggatcttga ggaagagctt tgctttcctc agcaggagca gttgatggag ctggttggct
    19501 tgggatttct agttttggtt tttcttcagc aatagcggct tgtccgtttt catcgcctac
    19561 atgtgttacc atagttccga cttcgactat ttgagtaacg gcttcctgtg ctacgacact
    19621 atttacaagt gttttcactt ccttaccatc ggcagaagtg ctcacagagt agaagttgct
    19681 acgatgtcca ttgacgccct tagtaatgac ttgtgttttt cctttgagta agagtggatt
    19741 ttcacgagtc actgtggtaa atggaatttc ttcttcttgg atatccagtc taggttttac
    19801 ctcagtagtt ggtgcaagac cactttcatc acccttgtga gttacaggag agccaacttc
    19861 aaccacttgg tttataactt ctttggttac ctggctatca aggactgttt ctgttgtttt
    19921 tccattttca gtgagtacag agatgtaatg agttcgttca cctttgactc ctgctgtgat
    19981 aatattttcc tgaccagctg ggaggttagg attttctttc ttgataactt caaatggaat
    20041 ttcttcagtt cttgtgatga gttctggtct ggtttcaaca ttggcagcca cttcattttc
    20101 atctaggctt cctgaatgag ttgcagctgg tttgaggcct tgaagagcgg cttttaggtt
    20161 ggctacaagt gtgtcaagct cagcttgttt attacggttg aggttgtaat ttagagctgt
    20221 tttagctgcg tcaagggcct caagactttc tttactatat ccttctaagt ttgtaggaat
    20281 tttagctaat tcttcgcgga gagcattata attagcacgg aagtagtctt tgttgtggtc
    20341 tgcaaaggca gtcatgagtt caaagatttc ctcttccttg tactcagcgc ttggtctatc
    20401 tgcccagatt gaaagcatac ttccgactgt tggaagatct acttcaggat atttggtaga
    20461 agctagttga ttgaatggaa ctttaccaga attttcaact gcttttgaaa gagggtaagc
    20521 ttcatcttgt ttgtgattgc ctataacata ataccagtca ccgttggtat tcaagaattt
    20581 atagcctttg cttgctaggt attgaggtga tgcgaggtta tatccccacc agcctttaga
    20641 ccagtaagaa atcaagacat ctttgtcaaa ctgaacatcg tccttgtctt catagtagaa
    20701 gccatcgttg aaggccattg gttgaagccc tctttctttg gccatagctg cgagggtgtt
    20761 ggcatattcg gcaaatttgc catagagttg ataccacttg aggtagtacc agccttgggc
    20821 actagtcgca tcgttggcgt attcgtcagt accaaagttg aaaatctttg ttttacctgc
    20881 aaagaagtcc atgtatttac cgatgagggc ttttacaaag ttcatcgctt cttcgttttt
    20941 caagtccata gttgtttttg aaactttatc aaagtgggct tgaggatttt taatacctaa
    21001 tttttccatg gcaaccagca tagcatccat gtgacctgga ctgttaatag ctgggatgag
    21061 accaatgtcc ttagatttag cgtattcaat tagctctgtc acttctgcct gtgttagtgc
    21121 agtaccgttt ggatcgtcgt agtaagcttt agttccttcg ataatagctt ttttaacgtc
    21181 atcactagca taggtttttc cgttggcagt aatggtcata tcattgagta gaaagcgaag
    21241 tccgtcattt cctagaagga gatggacatc agaatatccg agctcactgg ccttgtctac
    21301 gatgcgtttg agctggtcca gagtaaagta tttgcgtcca gcatcgattg agattacctt
    21361 gtttttggca agtttttcaa cctcacgttt agcttcttct tctttttgag cttcaggcgt
    21421 gagggtcaag ttgttgacag tttcttgaag tttagcaatg gcttgatcaa tcgtatcttg
    21481 ttgggcacgg ctaaggttgc tatcgagaga gcgaatagct ttttcagctt cttttacggc
    21541 cgcgacgctt tctgcagtat aacggttcag gtcttttggt acctcgttaa gtgcttgctc
    21601 tgcagattca taatcagctg cgaagtattc agcgttggca tttgcaaaat gacgcatgag
    21661 tttgaagagg tgtgatggtg aataacgtgc agatggagtg tcagcccaag cagctaccat
    21721 accaccgatg attgggatat cagctccttc tgtttttggt acagaagtga ttggtgtgtt
    21781 tttaatacca ttgagcccct gatcgagatt gtaccagcct tggccatcag cgtttcgtcc
    21841 aagaacgtag taccaagcat cattggtatt aaggatttgg tgaccttttt cagctagtag
    21901 tttagaagaa gcgacatcgt agcctcccca accaccagtc cacatagaaa cgatgatgtc
    21961 tttgtcaaaa ctaccaaagc ttgtgtcgct attgtagtag ataccgtcgt taaaggccat
    22021 tggtttgaga ccgtgcgatt ttacaatacg agcgaggtca ttggcgtagg caataaattt
    22081 ttcatagcct tttacagggt agccttcgtt tggatagtat ttatcagctt gaagcacact
    22141 ccaaccttta gcatctgtcg catcattggc atattcatca agtccgatgt tgaagatttc
    22201 agtctttttc gcgaaataag cagcatactt gtcgataagg gcttttgtaa aagcgacagc
    22261 ttgttcgttg tcaagatcga cagtacgggc tgattccttc ccaaaatagc taaagttagg
    22321 gttttggatt cccaattctt tcatggcatt gagaatcgca tccatgtgac caggactatt
    22381 tactgtcgga atgagaccga tacctttatc ttttgcatag ttaatcagat ctgtcatttg
    22441 actttctgtt aagtgattgc cgtttggatc gttgtaataa tcatttgtac ctttttcaat
    22501 ggcgcgtttg acatcgtcac tggcataggt cttgccgtta gctgtgatgc tcatatcgtc
    22561 caacatgaaa cggagtccat catttccgac taataggtgt aaatcagtgt agccataatg
    22621 tttcgcttta tcgatgattt ccttgagctg ttctggtgag aaatatttac gtccagcatc
    22681 aatagaaaca attttctttt tcgctagttt ttcatttaca gttgcagcac gttcctttcc
    22741 tgcctctgtt tccggtttgt cagcctctgc tttcgcttca tcttttttag ctggtttatc
    22801 cttgtcagtc ttgtctgtat ttgactcttt agaatcaacc tctttcgctt cttccttttt
    22861 agggctagct tcttctgcct ttttattagc agtttctttt tcagcagaag ttggagttac
    22921 cacttctgct ttatcactag gagttgaact aacttcctct tgtggttttt cttctgtttt
    22981 tggaagacta gctaccttat cagtagctgg agtttctgtt tctacagttt ttggagcttc
    23041 tggttgaagc actgctttag gtgtttcctc agtccgattt tcggatgatt gaggggaatc
    23101 agaaaccgta tggatggtcg gttggttttc tgtagtagta ggagtaactc catcggctgc
    23161 aacagtctgt gcttggaagg caaatccaat tagaacagaa gctgctccta cagcgtattt
    23221 acgaatagaa aaacgctgtt gtttttcatg tttcattgca aaacctcctg attgcattgt
    23281 tatattgata gcgattatat aaatcaacgc ctttatttta tttcttatat taacgagagt
    23341 caagaggaga tgacaaaaaa ctataataag tataaaaaaa tataaaattt aaacttaaga
    23401 tttcagattg gtcggaaaaa atacgtatat atatctagta taatttttgg ttctatttct
    23461 ataaaatatt ccacaaatta tagaattttc caaaaatagg taagcgctac ctttttggtg
    23521 tagtataata agcatagaaa aagcccaagc gattagctca ggttttcttc ttagtgatca
    23581 cggtcacatg agataaattt aatcttgtag taatcagatc gtttgtaagt ttcactgtat
    23641 tctaaaactt ggccagttga ttcgagtttg gtgattttag tttgtaggac agtagggaat
    23701 tgttcatcga ctccgaggac tgaagctgca tgttctggag ttggaaagac tatttcgttg
    23761 atttcttcaa agtgttcatc attcatgtga atgtggtagt ctaacttgaa acgattatag
    23821 atagaactat agtattcaag gtttggataa tttgcgttga tatattgttc tgggatgtag
    23881 gatgtatggt agatataaac gacaccgttt gattcgcgga tacgttcaat cttgtagtag
    23941 aattgatcgc cgcgtagacc caatttttcc aagtaaacaa gcttgtttcc gcgttcaatt
    24001 gaaagaacag ttaccttatc atctttagca ttgaagagtt caatatctga aaactctaca
    24061 agcttgtgtt tgcgtgcacg tgaaacgaag gttccttttc cttgttggcg gacaatatag
    24121 ccatctttgg caaggtcgtt taaggcgcga acaactgtga tagagctgac atcgtacatt
    24181 gaaatgagtt ctgcttcagt gtaaaattta tctccactgc taaactgccc agagatgatt
    24241 ttatttttta attcgtcttt tatgtattga tatttgggaa ttgccatatt tttacctcta
    24301 ttttccttct tccatagaaa attttaccat aaaagcgaaa aaaatagtag tcttttgaat
    24361 aaaaaattag aataatagtt tgaaaaatta agcgatatag ggattgctca tattttataa
    24421 atgtattcta tacaaaatta ttttaggtcc tatattccga atttaaagag cgtttgaaat
    24481 gggtctaaaa atgtttgaaa ctaattgaat gtgtgtataa tagtaaaaat gcagtaaata
    24541 tcccgacaat ttctattgac aattcaaaca gattggttta taattaatat aacaacaaat
    24601 gaaagcgcaa actttcgcgg tcggaaggta gttttatgac acgatttgag atacgagatg
    24661 atttctatct cgatggaaaa tcatttaaga ttttatctgg tgccattcat tattttaggg
    24721 ttcctccaga ggattggtat cattcgctct ataacttgaa ggctcttggt tttaatacgg
    24781 tagagactta tgttgcttgg aatttacacg agccttgtga aggtgagttt cattttgaag
    24841 gtgatctgga tttagagaaa tttctccaaa tagcgcagga tttgggtctc tacgcaattg
    24901 tgcgtccgtc tccatttatc tgtgcggaat gggaattcgg tggcttacca gcttggctct
    24961 tgaccaagaa catgcgaatt cgctcatccg acccagcata tatcgaggca gttggtcgct
    25021 actatgatca gttattgcca agactggtgc ctcgtttgtt gaacaatggt ggcaatattc
    25081 tcatgatgca ggttgaaaat gagtatggtt cttacggaga agataaggct tacctgagag
    25141 cgattcgaca gctaatggaa gagtgtggcg taacctgtcc cctctttaca tcagatggtc
    25201 catggcgagc tactctgaaa gctggaacct taattgaaga ggacctcttt gtaacaggaa
    25261 actttggttc taaggcacct tacaactttt cgcagatgca ggaattcttt gatgaacatg
    25321 gtaagaaatg gccactcatg tgtatggagt tctgggatgg ttggttcaat cgctggaaag
    25381 aaccgattat cacacgggat cctaaggaat tggcagatgc agttcgagag gttttggaac
    25441 aaggctctat caatctttac atgttccacg gtggtacaaa ctttggtttc atgaatggtt
    25501 gctcagctcg aggaactttg gacctgccac aagttacatc ttatgattac gatgcccttc
    25561 tggatgaaga aggaaatcca actgctaaat atcttgcagt caagaagatg atggcaacac
    25621 atttttcaga gtatccgcag ttggaaccac tctacaaaga gagtatggag ttggatgcta
    25681 ttccactagt tgaaaaagtt tctttgtttg aaaccttaga tagcttgtca agtcctgtag
    25741 aaagtctcta tcctcaaaag atggaggagc tgggacaaag ttatggctac ctactttatc
    25801 gaacagaaac aaactgggat gcagaagaag aaagacttcg tatcattgat ggtcgagata
    25861 gggcccagct gtatgtcgat ggtcagtggg ttaaaactca atatcagaca gagattgggg
    25921 aagatatttt ttatcaaggt aaaaagaaag ggctatctag gttagatatc ttgatagaaa
    25981 atatggggcg tgtcaactat gggcataagt tcttagcgga tacgcaacgt aagggaattc
    26041 ggacaggggt ctgtaaggat ctgcatttct tactaaactg gaaacactat ccactcccac
    26101 tagacaatcc tgagaaaatt gatttttcaa aaggatggac tcaaggacaa ccagcctttt
    26161 acgcttatga ctttacagtc gaagagccaa aagatactta cctagacttg tctgagtttg
    26221 gtaagggagt tgcctttgtc aatgggcaga atctaggacg tttttggaac gttggcccaa
    26281 ctctctcact ttatatccct catagctatc tcaaggaagg tgccaaccgc atcattatct
    26341 ttgaaacaga aggtcaatat aaagaagaga ttcatttaac tcgtaaacct acactaaaac
    26401 atataaagga ggaaaactta tgacaattgt aggatgccgt attgatggac gtttgatcca
    26461 cggacaagta gccaatcttt gggctggaaa actaaatgtt tcacgcatta tggttgtaga
    26521 cgacgaagtt gtcaacaacg atattgaaaa gagtggtttg aaacttgcga caccaccagg
    26581 tgtgaaattg agtattttgc cagttgagaa agctgcagcc aatattcttg gtggcaaata
    26641 cgatagccaa cgtctcttta tcgtggctcg taaaccagac cgcttccttg gtttggtaga
    26701 agcaggtgta ccacttgaaa cccttaatgt tgggaatatg tctcaaacac cagaaactcg
    26761 ttctattaca cgttctatca acgtagtaga caaggatgtg gaagacttcc acaaactggc
    26821 agaaaaaggt gttaaactta ctgctcagat ggttccaaat gatccaattt cagacttttt
    26881 gagcttatta aaataggaaa aaaattttta ggaggtcatt gttatgatac aatggtggca
    26941 aattttactt ctcactttgt actcagctta tcaaatctgt gatgagttga cgatcgtttc
    27001 atctgcaggt tcccctgtat ttgctggttt cattactggt ttaatcatgg gagatgtgac
    27061 tactggttta cttatcggtg gtaacttgca actgttcgtt cttggggttg gtaccttcgg
    27121 tggtgcttct cgtatcgacg caacttctgg tgcggttctt gcgacagcct tctctgtttc
    27181 acaaggaatt gatgcaccgc ttgccattac tacaatcgct gtaccagtag cagctctctt
    27241 gacttacttc gacgttcttg gtcgtatgac tactaccttc ttcgctcacc gtgtggatgc
    27301 tgcaatcgaa cgctttgact ataaaggtat tgaacgcaac tacttgcttg gtgcgattcc
    27361 gtgggctcta tctcgtgccc ttccagtctt ctttgccctt gcttttggtg gtgcctttgt
    27421 acaatcagta gtagacttcg ttgaagccta caaatgggtt gcagatggct tgacactcgc
    27481 aggacgtatg cttccaggtc ttggatttgc aatcttgctt cgttaccttc cagttaaacg
    27541 taaccttcac taccttgcta tgggatttgg tttgacagct atgttgactg ttctttactc
    27601 atatgtaaca ggtcttggtg gcgctgttgc tggtatcgta ggtactcttc ctgctgaagt
    27661 tgctgaaaaa attggtttcg tgaacaactt caaaggtttg tctatgattg gtatttctat
    27721 cgtaggtatt ttccttgcag tgcttcactt caaaaatagc caaaaagtag ctgtagcagc
    27781 accttctaca ccatcagaaa gtggggaaat cgaagatgac gaattctaat tacaaactta
    27841 caaaagaaga ttttaatcaa atcaacaaac gtagcttgtt tactttccaa ttaggttgga
    27901 actacgaacg tatgcaagct tctggttacc tttacatgat cttgcctcag ttgcgtaaaa
    27961 tgtatggtga tggaactcct gaattgaaag aaatgatgaa agttcatact caattcttca
    28021 atacttcacc attcttccat accattatcg ctggttttga ccttgccatg gaagaaaaag
    28081 atggtgtagg ttcaaaagac gccgttaacg gtatcaagac aggtttgatg ggaccattcg
    28141 ctcctcttgg ggatacaatc tttggttcac ttgtacctgc tatcatgggg tcagtcgcag
    28201 caactatggc tatcgctggc caaccttggg ggatcttcct ttggattgca gttgcagtag
    28261 cgtatgacat cttccgttgg aaacagttgg aatttgctta caaagaaggg gttaacctta
    28321 tcaacaacat gcaaagtacc ttgacagctt tgattgacgc tgcatccgta cttggtgtct
    28381 tcatgatggg tgctcttgta gcaacagtga ttaactttga aatttcttac aagttgccaa
    28441 tcggtgaaaa gatgattgat ttccaagaca tcttgaacca aatcttccca cgtttgcttc
    28501 cagcaatctt tactgccttt atcttctggt tgcttggtaa gaaaggtatg aactctacta
    28561 aagctatcgg tattattatc gtacttgctt tggctctttc tgcccttggt cactttgcac
    28621 ttggaatgta attccttatg actaaatcat taattttggt gagccatggt cgcttctgtg
    28681 aggagcttag aggtagcaca gaaatgatta tgggcccaca agacaacatt tacacagtag
    28741 ctcttcttcc agaagatggc ccagaagaat ttactgctaa gtttgaagct gttattgaag
    28801 gattggatga tttcctagtc tttgcggatc ttctcggtgg gacaccttgt aatgtggtga
    28861 gtcgcttgat catggaaggt cgtgatattg acctttacgc agggatgaat cttccaatgg
    28921 tgattgaatt tatcaatgcg agccttacag gcgcagatgc ggactacaag agccgtgctg
    28981 cagaaagcat tgtgaaagtt aatgacctgt tagcgggctt cgatgatgac gaagatgaat
    29041 aatactcttc gaaaatctct tcaaactacg tcaacgtcgc cttaccgtag gtatatgtta
    29101 ctgacttcgt cagtcttatc cggcaacctc aaaacggtgt tttgagctga cttcgtcagt
    29161 cttatccggc aacctcaaag cagtgctttg agcagcctgc ggctagtttc ctacagattt
    29221 tagttggaac tcgattcaat tcatgtgaca acgtgaaaat cgttagagca ttttatatag
    29281 aatatacatg ggaatggagc ttactcccat tcctatattt aatagaaaaa gaggaactca
    29341 atgctacatt atacaaaaga agacttgctc gaattgggtg cagaaatcac tacgcgtgaa
    29401 atctaccaac agcctgatgt atggagagaa gcttttgaat tttatcaagc aaaacgtgaa
    29461 gaaattgcag ccttcctaca agaaatcgct gataaacatg actatattaa ggttatcttg
    29521 acaggtgctg ggacttctgc ttatgtggga gacaccttgc taccttactt taaggaagtc
    29581 tatgacgaac gcaaatggaa tttcaatgct attgcgacaa cagatatcgt tgccaatcca
    29641 gcaacctatt tgaaaaaaga tgtggcaact gtccttgtgt cttttgctcg tagtgggaac
    29701 tcgcctgaaa gtgtggcgac tgttgatttg gccaaatcct tggtggatga gctttatcaa
    29761 gtgacgatta cttgtgcaac agatggtaaa ttggctcttc aagctcacgg tgatgaccgt
    29821 aatctcttgc tcttgcaacc agctgtctct aatgatgctg gatttgccat gacttctagc
    29881 tttacgtcta tgatgttgac agctctcttg gtctttgatc ctacagaatt tgctgttaag
    29941 tctgaacgtt ttgaagttgt atctagtctt gcccgtaaag ttttagacaa ggcagaagat
    30001 gtcaaagagc tcgttgattt agactttaac cgtgtcatct atctaggcgc tggtcctttc
    30061 tttggacttg ctcatgaagc tcagctcaag attttggaat taactgctgg tcaagttgcg
    30121 accatgtatg aaagcccagt tggcttccgt cacggtccaa aatctcttat caacgacaat
    30181 acagttgttt tggtctttgg tacaacgaca gactacactc gtaagtacga cttggacttg
    30241 gttcgtgaag ttgctggtga ccagattgct cgtcgtgttg tgcttttgag tgatcaagct
    30301 tttggtcttg aaaatgtcaa agaagtggcc cttggttgtg gcggtgtctt gaatgatatt
    30361 taccgtgtct tcccttacat cgtttatgcc caactctttg ccctattgac ttcacttaag
    30421 gtagaaaata aaccagatac accgtctcct acaggtacag taaaccgtgt agtacaaggt
    30481 gtcataattc acgaatatca aaagtaagac agtgtttatg aattcttgac aagaggattt
    30541 gtaaattatc agataaacca tagattgtca gtacgctttc tatggtttgt ttgcttgaga
    30601 gaaatagtaa aaggagaaca gaatgaaagc atacacagag cgtgtatttg gaaatgttga
    30661 gggcgaggat gtcttggcct atcgatttga gacagacggt ggctaccaac ttgaggttat
    30721 gacttatggt gcgaccatct tgcgctatgt cgcacctgac aaggctggaa attttgccaa
    30781 tgttatcttg ggatttgatg actttgatag ttatgtaggc aatagtccca agcatggagc
    30841 aagtgtaggt cctgtagcgg gtcgtattgc aggtgcgacc tttgagctca atggtaagac
    30901 ctatgacctt gaggttaata atgctagcaa ctgtaatcac agtggttcaa ctggttggga
    30961 ttccagcttg tttgaagttg aagaagtaag cgatcatggc ttgactctct acacagagcg
    31021 tacagatggg acaggagggt tccctggaaa tctcaagatt tggatcagtt atcacttgga
    31081 agaaactggt gcctatgaaa tcagctacaa ggtgacgacc gatcaggata cgctggtcaa
    31141 tccaaccaac cacagctatt tcaacttgtc tggtgatttc acgcagacga ttgaccgtca
    31201 tgtcttccaa ctaaacacag agggcattta ctcaatcgct cctgacggtg ttcctgccaa
    31261 aactccagaa gccaaccgtg atgtggtcaa acacgtctac aatggtacct tgttgaagga
    31321 tatctttgca gaagaagatg agcaaatcca gctggcatca ggtttggatc atccatttgc
    31381 ccttcctgca ggccatgaca atgctggatt cctttatgac caaaattcag gtcgcttcct
    31441 gcttttcaag acagaagctc cttgctttgt ggtctacaca gcaaactttg tggatgaaag
    31501 tgtcatcata ggaggtcagc caatgctaca gcacaatggg attgctcttg aagcgcaagc
    31561 tttaccagat gccattcaca gtgaccttaa aggccaagtc attcttaaag ctggtcaaac
    31621 cttcaccagt aagacacgtt atgaacttgt tgtgaaataa aaaagctggt caaaaagtct
    31681 ttaaaattaa aataacgcat attgtcaggt gatgaaaagt ttgataatat gcgttttatt
    31741 atgaaatgat ttactttata ttatcctgaa atggtgttat ttttgagtta tctggcttga
    31801 ctttcttgat ggaaattata taatagttgt aataataata attacaacga gaaaagagga
    31861 ccatttatga cctatgaata taagagtcac atttatttgg cagagacagc tttaaatgta
    31921 aaggatttgg ccagtcaaac agccttttat cagcaagtta ttggtttaga aatcttatct
    31981 caaactgaga cagagtccat tctaggcctt ggtggaaaag tcttggtaca gctgattcaa
    32041 gcacaagaga gcggagaagt gagggaacat tatggtcttt accatttggc cattctcttg
    32101 cccacacgca aggctttggc tgatgtcttg aaacacctga cagatttgca aattcctctt
    32161 gtcggcggtg cagaccatgg ttacagtgaa gctatttact tggaagattt ggagggaaat
    32221 ggcattgaac tctatcgaga taagccagtt tccacatggg atattcgaga agatggacgc
    32281 attatcggag tgacggaggc tcttgcggcg caggacattt atgagttggg ggaaagagta
    32341 gagcccttta tcctggcaga aggtacaaga atggggcata ttcatctttc cgtcaaggat
    32401 agtcgaaagt ccagccagtt ttatcaaaag gtgttagggc tagagaataa attcagtgtg
    32461 cctggcgcta gttggattgc ggctggagat taccatcatc atttagcagt taacgaatgg
    32521 agaggaaaag gtctggcttc gcgtaagcaa ggcttaccag gtttagccta ctatgtcatc
    32581 gaagtcgcac ataaaaaaga actgttaacg attgcccaac gagcacaaga agttgacgca
    32641 ccaatcaaat ggatgacatc gagcaaattg gaaatcacag actcagatgg catcgtgacc
    32701 cgtattcgtt tagcaaggta aaattaggaa tttttaataa gttataagta ttgctagttt
    32761 gctttttgaa cggtctttgg taacagaact gcgtgagctg gatgggtgag aattttgaca
    32821 aagaagctga ttagagatat aatgaagaaa aatcgagcaa ggaaaaagaa atgacaaatt
    32881 caaagtatat tacttgtttg aaacgttcag agggccagtt gcgtgggatt caaaagatga
    32941 ttgaaggaga tcgtgactgt gctgatattg tgacgcaact gacagcagtg agatctagtg
    33001 tagagcgcgt gattgagatg ataattaccg aaaatcttac tgaatgtatc aatcagccac
    33061 tagatgattc tgaagctcaa aaggaacgcc tagaaaaggc tatccgatac ttgattaaac
    33121 ggaaataaat gaatgttttg agacgatatg tgcaaaggtc tattaactat tagaatagtt
    33181 taatgtgagt caaaagaagt tgtaaaaaat ctttaaaatt aaaaaacgca tagtatcagg
    33241 tattgaaatg tactgccccc caaaagttag attctttctg tctaactttt ggggggcagt
    33301 acataaaaac cttgatagta tgcgttttat tgtggggaga cttatactct tcgaaaatct
    33361 cttcaaacca cgtcagtttc accttgccgt agatatggtt actgacttcg tcagttctat
    33421 ccacaacctc aaaacagtgt tttgagctga ctttgtcagt tccatccaca accttaaaac
    33481 agtgttttga gcagcctgcg gctaacttcc tagtttgcac tttaattttc attgagtatt
    33541 acttcatctt ctcatgaaat tgagtttttg cccagctcct cttgattatt ctacttgacc
    33601 gggccaagta ttcataccac cttctacgtt ggtaacggtg aggccttggg agctgagaaa
    33661 ttggcaggta gatgcagagc ggactcctcc ttgacaaata acatagtatt catggtcagg
    33721 tttgagttct ttgtagcctt gctctaaggt acttaatgga agatttttgg cacctggtgc
    33781 atgtcctgct tggaattcat gtgcttcacg gacatcgata agttctagat tttcatttta
    33841 gtattttcca taaaagtcag ccatgctgat actagtttcc atattctact ccttctgggt
    33901 tagccatttt gtatagtgaa taagcgccgt caaggttttg gacggtaaat cctgcttgct
    33961 tgaggatagg ctctgcgata tagctgcgca aaccactgtg gcagctgacg atgtaggctt
    34021 gttttttgtc cagttcatca gcttcctcct tgacactttg tcagtttttg atacaatagt
    34081 acaaaattag aggaggtggg ctatgattca gaaacatgcg attcccattt tagagtttga
    34141 tgataatcct caggcggtta tcatgcccaa tcacgagggg ttggatttgc agttgccaaa
    34201 gaagtgtgtc tatgcttttt taggtgagga gattgaccgc tatgcgaggg aagtaggggc
    34261 gaactgtgtt ggcgaattcg tttctgctac caagacctat ccagtctatg tcatcaacta
    34321 caagggtgag gaggtctgtc tggctcaggc tcctgttggc tccgctccag cagcccagtt
    34381 tatggattgg ttgattggct atggtgtgga gcagattatc tctactggga cctgtggtgt
    34441 cctagctgat atagaggaaa atgcctttct agtccctgtt cgcgctttgc gagatgaggg
    34501 agccagttac cactatgtgg caccttgtcg ttatatggaa atgcagccag aggctattgc
    34561 tgctattgag gaagttttgg aagacagagg gattccttat gaagaagtca tgacctggac
    34621 gacagacggt ttttaccgag aaacggctga aaaggtggct tatcgtaagg aagaaggctg
    34681 tgctgttgtg gagatggagt gttctgctct tgcggcagta gctcaattgc gtggggttct
    34741 ctggggtgaa ttgttgttca cagcagattc tctagcggac ttggaccagt acgacagtcg
    34801 tgactggggc tcggaagctt ttaataaggc gctagaactg agtttagcaa gtgttcacca
    34861 cctttagttg tactggcaaa ggatttgttt tatcataaaa tgtctagctc atacttttca
    34921 aaaatatgtt taaacgaggt caccttcctc ttgtcctagg catgttgagg ttgggaaaaa
    34981 tctttaaaat cagaaaaacg tatcatatca ggtgataaaa actttgatac tatgcgtttt
    35041 atgttggtaa gatttagagt gagatgaaat gatactcttc gaaaatctct tcaaaccgcg
    35101 tcaacgtcgc cttgccgtat agatgttact gacttcgtca gttctatctg caacctcaaa
    35161 acagtgtttt gagctgactt cgtcagttct atccacaacc tcaaaacagt gttttgagca
    35221 acctgtgact agctttctaa gcgatgcctt ggttctcatt gcctataatc aaaaagagaa
    35281 attttctcct gaaaagcata tagagtagct ggcgttaaaa gctcctgtct tgcttttttg
    35341 acctatagtc acatctatca agtattgttc ttgcctaagc tatcaataaa aaggtggcat
    35401 tttttaggct tggtgttagt gaattttgcc ttatcctatc taagtcattt cgagcttttt
    35461 atggtacaat ggaaacatgt tattcaaatt atctaaggaa aaaatagagc taggcttatc
    35521 tcgtttatcg ccagcccgtc gtattttttt gagttttgcc ttggtcattt tactaggctc
    35581 tcttcttttg agcttgccct ttgtccaagt tgaaagctca cgagcgactt attttgatca
    35641 tcttttcact gctgtctctg cagtctgtgt gacaggtctc tcaacccttc cagtagctca
    35701 cacctataat atatggggcc aaataatctg tttgctcttg attcagatcg gtggtctagg
    35761 gctcatgacc tttattgggg ttttctatat ccagagcaag caaaagctta gtcttcgtag
    35821 ccgtgcaact attcaggata gttttagtta tggagaaact cgatctttga gaaagtttgt
    35881 ctattctatt tttctcacga cctttttggt tgagagcttg ggagctattt tgcttagttt
    35941 tcgccttatt cctcaacttg gctggggacg tggtcttttt agttccattt ttctagcgat
    36001 ctcagccttc tgtaatgccg gttttgataa tttagggagc accagtttat ttgcttttca
    36061 gaccgattta ctggtcaatc tggtgattgc aggcttgatt attacaggcg gccttggttt
    36121 tatggtctgg tttgatttgg ctggtcatgt aggaagaaag aaaaaaggac gtctgcactt
    36181 tcatacgaag cttgtattat tattgactat aggtttgttg ttatttggaa cggcaactac
    36241 tctctttctt gagtggaaca atgctggaac gattggcaat ctccctgttg ccgataaggt
    36301 tttagttagc ttttttcaaa cagtgacgat gcgaacagct ggcttttcta cgatagatta
    36361 tactcaggct catcctgtga ctcttttgat ttatatctta cagatgtttc taggtggggc
    36421 acctggagga acagctgggg gactcaagat tacgacattt tttgtcctct tggtctttgc
    36481 acgaagtgag cttctaggct tgcctcatgc caatgttgcg agacgaacga ttgcgccgcg
    36541 aacggttcaa aaatccttta gtgtctttat tatctttttg atgagcttct tgataggatt
    36601 gattctgcta gggataacag ccaaaggcaa tcctcccttt atccacctca tatttgaaac
    36661 catttcagct cttagtacag ttggtgtaac ggcaaatctg actcctgacc ttgggaaatt
    36721 ggctctcagt gttatcatgc cacttatgtt tatgggacga attggtccct tgaccttgtt
    36781 tgttagcttg gcagattacc atccagaaaa gaaagatatg attcactata tgaaagcaga
    36841 tattagtatt ggttaagaaa ggaaagagca tgtcagatcg tacgattgga attttgggct
    36901 tgggaatttt tgggagcagt gtcctagctg ccctagccaa gcaggatatg aatattatcg
    36961 ctattgatga ccacgcagag cgcatcaatc agtttgagcc agttttggcg cgtggagtga
    37021 ttggtgacat cacagatgaa gaattattga gatcagcagg gattgatacc tgcgataccg
    37081 ttgtagtcgc gacaggtgaa aatctggagt cgagtgtgct tgcggttatg cactgtaaga
    37141 gtttgggggt accgactgtt attgctaagg tcaaaagtca gaccgctaag aaagtgctag
    37201 aaaagattgg agctgactcg gttatctcgc cagagtatga aatggggcag tctctagcac
    37261 agaccattct tttccataat agtgttgatg tctttcagtt ggataaaaat gtgtctatcg
    37321 tggagatgaa aattcctcag tcttgggcag gtcaaagtct gagtaaatta gacctccgtg
    37381 gcaaatacaa tctgaatatt ttgggtttcc gagagcagga aaattcccca ttggatgttg
    37441 aatttggacc agatgacctc ttgaaagcag atacctatat tttggcagtc atcaacaacc
    37501 agtatttgga taccctagta gcattgaatt cgtaaagagg gatgacccct cttttttgat
    37561 gcttaagatg gcaaatagag acagaagccc cttgtcttct agtaaaagtt cttcaaaggc
    37621 tggactttat ggtaaaatag aaggaagtga caagagagag taatactcaa tgaaaatcaa
    37681 agatcaaact aggaaactag ctgcgggctg ctcaaaacac tgttttgagg ttgtggatag
    37741 aactgacgaa gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag
    37801 ctcaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagtaaca tctatacggc
    37861 aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt ataagaaaaa atcagtcccc
    37921 taaaggagca gattatgaag ttattgtcta tcgccatttc tagctataat gcagcagcct
    37981 atcttcatta ctgtgtggag tcgctagtga ttggtggtga gcaagttggg attttgatta
    38041 tcaatgacgg gtctcaggat cagactcagg aaatcgctga gtgtttagct agcaagtatc
    38101 ctaatatcgt tagagccatc tatcaggaaa ataaaggcca tggcggtgcg gtcaatcgtg
    38161 gcttggcaga ggcttctggg cgctatttta aagtagttga cagtgatgac tgggtggatc
    38221 ctcgtgccta cttgaaaatt cttgaaacct tgcaggaatt tgagagcaag ggtcaagagg
    38281 tggatgtctt tgtgaccaat tttgtctatg aaaaggaagg tcagtcttgt aagaagagta
    38341 tgagttacga ttcagtcttg cctgttcggc agatttttgg ctgggaccag gtcggaaatt
    38401 tctccaaagg ccagtatatc atgatgcact cgctgattta tcggacagat ttgttgcgtg
    38461 ctagccagtt ctaattgcct gaacatactt tttatgtcga taatctcttt gtctttacgc
    38521 cccttcagca ggtcaagacc atgtactatc tgcctgtcga tttctatcgt tatttgattg
    38581 ggcgtgagga ccagtctgtc aatgagcaag tgatgattaa gtgcattgac cagcaactca
    38641 aggtcaatcg actcttggta gaccaacttt atttgtccca agtgagtcat cccaaaatgc
    38701 gagaatatct gctgaatcat attgaaatca cgacggtgat ttccagtacc ctgctcaacc
    38761 gatctggaac agcggagcat ctggcaaaaa aacgccaatt gtggacctat attcagcaga
    38821 aaaatccaga agtctttcag gctattcgta agaccatgtt gagccgtttg accaaacatt
    38881 ctgtcttgcc agatcgcaaa ctgtccaatg tcgtctatca aatcaccaaa tctgtttatg
    38941 gatttaatta atataagtgt tttataagag ggatttaaga aaaattttaa ctttttctta
    39001 gtccttttta atttcaggag attatactag agtcatcaaa taaagaaaga ctctaaggag
    39061 aatcctatga aattcaatcc aaatcaaaga tatactcgtt ggtctattcg ccgtctcagt
    39121 gtcggtgttg cctcagttgt tgtggctagt ggcttctttg tcctagttgg tcagccaagt
    39181 tctgtacgtg ccgatgtggt caatccgacc ccaggtcaag tcttacctga agagacatcg
    39241 ggaacgaaag agggtgactt atcagaaaaa ccaggagaca ccgttctcac tcaagcgaaa
    39301 cctgagggcg ttactggaaa tacgaattca cttccgacac ctacagaaag aactgaagtg
    39361 agcgaggaaa caaactcttc tagtctggat acactttttg aaaaagatga agaagctcaa
    39421 gaaaatccag agctaacaga tgccttaaaa gaaactgtag atacagctga tgtggatggg
    39481 acacaagcaa gtccagcaga aactactcct gaacaagtaa aaggtggagt gaaagaaaat
    39541 acaaaagaca gcatcgatgt tcctgctgct tatcttgaaa aagctgaagg gaaaggtcct
    39601 ttcactgctg gtgtaaacca agtaattcct tatgaactat tcgctggtga tggtatgtta
    39661 actcgtctat tactaaaagc ttcggataat gctccttggt ctgacaatgg tactgctaaa
    39721 aatcctgctt tacctcctct tgaaggatta acaaaaggga aatacttcta tgaagtagac
    39781 ttaaatggca atactgttgg taaacaaggt caagctttaa ttgatcaact tcgcgctaat
    39841 ggtactcaaa cttataaagc tactgttaaa gtttacggaa ataaagacgg taaagctgac
    39901 ttgactaatc tagttgctac taaaaatgta gacatcaaca tcaatggatt agttgctaaa
    39961 gaaactgtcg aaaaagctgt taaagataac gttaaagaca gtatcgatgt tccagcagcc
    40021 tacttagaaa aagccaaggg tgaaggtcca ttcacagcag gtgtcaacca tgtgattcca
    40081 tacgaactct tcgcaggtga tggtatgttg actcgtctct tgctcaaggc atctgacaag
    40141 gcaccatggt cagataacgg
//
LOCUS       DAVKXA010000015        40059 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKXA010000015 DAVKXA010000000
VERSION     DAVKXA010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.015"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..321
                     /locus_tag="VW883_000831"
     CDS             <1..321
                     /locus_tag="VW883_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274001.1"
                     /translation="LEYSNSRTEFYEKKRNLSSSFHFLSPKLENEKNDNFREIAESRV
                     SKVFGTMNSIANTAYKPNYDYTNQQVEEIFEGYKNKIVEIKGIYSPLEKFLFSTQSKI
                     IIEK"
     gene            328..606
                     /locus_tag="VW883_000832"
     CDS             328..606
                     /locus_tag="VW883_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274002.1"
                     /translation="MEFWNDTIQTVKEWRPVNYSVAEDEDFEAVKKKAIRNFQDYLKL
                     LDENTEEGYQEVIRLFTFSKFYGEELCNDEELNKLSRDIRGRLKKFRS"
     gene            868..2145
                     /locus_tag="VW883_000833"
     CDS             868..2145
                     /locus_tag="VW883_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0274003.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETMIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2221..3705
                     /locus_tag="VW883_000834"
     CDS             2221..3705
                     /locus_tag="VW883_000834"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0274004.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     NKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNALNSQGQYELTNFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAIASAVYRKYQATTGDATKTVIASTASPYKFPVVAVEALTGKVGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTIVAAADMQVAVEAYLGL"
     gene            3766..5046
                     /locus_tag="VW883_000835"
     CDS             3766..5046
                     /locus_tag="VW883_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0274005.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMNLKG"
     gene            5050..5670
                     /locus_tag="VW883_000836"
     CDS             5050..5670
                     /locus_tag="VW883_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0274006.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFALFSIRYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5836..6978
                     /locus_tag="VW883_000837"
     CDS             5836..6978
                     /locus_tag="VW883_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0274007.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7384..7722
                     /locus_tag="VW883_000838"
     CDS             7384..7722
                     /locus_tag="VW883_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0274008.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7733..8091
                     /locus_tag="VW883_000839"
                     /pseudo
     CDS             7733..8091
                     /locus_tag="VW883_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8198..8815
                     /gene="pcp"
                     /locus_tag="VW883_000840"
                     /pseudo
     CDS             8198..8815
                     /gene="pcp"
                     /locus_tag="VW883_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(8843..9700)
                     /locus_tag="VW883_000841"
     CDS             complement(8843..9700)
                     /locus_tag="VW883_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0274009.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9830..10972
                     /gene="tgt"
                     /locus_tag="VW883_000842"
     CDS             9830..10972
                     /gene="tgt"
                     /locus_tag="VW883_000842"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0274010.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11070..12887
                     /locus_tag="VW883_000843"
     CDS             11070..12887
                     /locus_tag="VW883_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0274011.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQESKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13040..14191
                     /gene="nagA"
                     /locus_tag="VW883_000844"
     CDS             13040..14191
                     /gene="nagA"
                     /locus_tag="VW883_000844"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0274012.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14354..15412
                     /locus_tag="VW883_000845"
     CDS             14354..15412
                     /locus_tag="VW883_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0274013.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15563..15928
                     /locus_tag="VW883_000846"
     CDS             15563..15928
                     /locus_tag="VW883_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0274014.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16004..16945
                     /locus_tag="VW883_000847"
     CDS             16004..16945
                     /locus_tag="VW883_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0274015.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDHKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16893..17909
                     /locus_tag="VW883_000848"
     CDS             16893..17909
                     /locus_tag="VW883_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0274016.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEVGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17911..18237
                     /gene="comGC"
                     /locus_tag="VW883_000849"
     CDS             17911..18237
                     /gene="comGC"
                     /locus_tag="VW883_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV0274017.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQAKAYKEYHDKNGGA
                     NRKVND"
     gene            18206..18634
                     /locus_tag="VW883_000850"
     CDS             18206..18634
                     /locus_tag="VW883_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0274018.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFSAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18639..18899
                     /locus_tag="VW883_000851"
     CDS             18639..18899
                     /locus_tag="VW883_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274019.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18862..19323
                     /locus_tag="VW883_000852"
     CDS             18862..19323
                     /locus_tag="VW883_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0274020.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS"
     gene            19301..19714
                     /locus_tag="VW883_000853"
     CDS             19301..19714
                     /locus_tag="VW883_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0274021.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            19851..20445
                     /locus_tag="VW883_000854"
                     /pseudo
     CDS             19851..20445
                     /locus_tag="VW883_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20506..21459
                     /locus_tag="VW883_000855"
     CDS             20506..21459
                     /locus_tag="VW883_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0274022.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21510..22700
                     /locus_tag="VW883_000856"
     CDS             21510..22700
                     /locus_tag="VW883_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0274023.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22849..23220
                     /gene="rnpA"
                     /locus_tag="VW883_000857"
     CDS             22849..23220
                     /gene="rnpA"
                     /locus_tag="VW883_000857"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0274024.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23195..24019
                     /locus_tag="VW883_000858"
     CDS             23195..24019
                     /locus_tag="VW883_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0274025.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24038..25024
                     /locus_tag="VW883_000859"
     CDS             24038..25024
                     /locus_tag="VW883_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0274026.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25075..25698
                     /locus_tag="VW883_000860"
     CDS             25075..25698
                     /locus_tag="VW883_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0274027.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25829..27286
                     /locus_tag="VW883_000861"
     CDS             25829..27286
                     /locus_tag="VW883_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0274028.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAVNNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSFMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIIIGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27309..27590
                     /locus_tag="VW883_000862"
     CDS             27309..27590
                     /locus_tag="VW883_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0274029.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27667..28152
                     /locus_tag="VW883_000863"
     CDS             27667..28152
                     /locus_tag="VW883_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0274030.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28169..28834
                     /locus_tag="VW883_000864"
     CDS             28169..28834
                     /locus_tag="VW883_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0274031.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            28838..29701
                     /locus_tag="VW883_000865"
     CDS             28838..29701
                     /locus_tag="VW883_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0274032.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKSCDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29703..30407
                     /locus_tag="VW883_000866"
     CDS             29703..30407
                     /locus_tag="VW883_000866"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0274033.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30586..32259
                     /locus_tag="VW883_000867"
     CDS             30586..32259
                     /locus_tag="VW883_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0274034.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32371..33462
                     /gene="ulaG"
                     /locus_tag="VW883_000868"
     CDS             32371..33462
                     /gene="ulaG"
                     /locus_tag="VW883_000868"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0274035.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33576..35552
                     /gene="tkt"
                     /locus_tag="VW883_000869"
     CDS             33576..35552
                     /gene="tkt"
                     /locus_tag="VW883_000869"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0274036.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLASKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35669..35968
                     /gene="yajC"
                     /locus_tag="VW883_000870"
     CDS             35669..35968
                     /gene="yajC"
                     /locus_tag="VW883_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0274037.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36015..36443
                     /locus_tag="VW883_000871"
     CDS             36015..36443
                     /locus_tag="VW883_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0274038.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36445..36855
                     /locus_tag="VW883_000872"
     CDS             36445..36855
                     /locus_tag="VW883_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274039.1"
                     /translation="MENLTNFYEKYRVYLTRPRLEILAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37155..39806
                     /gene="adhE"
                     /locus_tag="VW883_000873"
                     /gene_synonym="adhC"
     CDS             37155..39806
                     /gene="adhE"
                     /locus_tag="VW883_000873"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0274040.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELSFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12286 a         7084 c         8959 g        11730 t
ORIGIN      
        1 ttagaatatt caaattcaag aacagaattt tatgaaaaaa aacgtaattt atcatcctca
       61 tttcattttt tatctccaaa attggagaat gaaaaaaacg ataattttag agaaattgct
      121 gaatcaagag ttagtaaagt atttgggaca atgaactcaa tagcaaatac tgcttataaa
      181 cctaattatg attatactaa tcagcaggtg gaagagatat ttgaaggata taagaataaa
      241 atagtggaga taaaaggtat ctatagtccg ttggaaaaat tcttgttttc aacccagagt
      301 aaaataataa ttgaaaagtg agataaaatg gaattttgga atgacacaat tcaaaccgtc
      361 aaagagtggc gaccagtcaa ttattcagtt gctgaagatg aagactttga agctgtgaag
      421 aaaaaagcaa ttagaaattt tcaagattat ctaaaattac ttgatgagaa tactgaagaa
      481 ggctaccaag aagttataag gttatttaca tttagcaaat tctatggtga agaactgtgt
      541 aacgatgaag aactgaacaa attgagtaga gatataagag gaagattaaa aaaattccgt
      601 tcctaaaaag ttactaaaaa tcaaaatttt attttttcaa acaatataaa tggtttttta
      661 taatgttgat tatgctgatt tataaagata taaaatctta aacactaaac tcaaaatcca
      721 gtgtccgcaa ggacgtgccg gttcgacccc ggccgccggt atagtatagt gttaggaacg
      781 ttgttattct tcgttccttt tttatattat ttttggtata attatagtta ttcaaatttt
      841 atttagattg agaaagtgta gggtagtatg tcttgttcta tcgatttatt aaaacatcgg
      901 tatttgaaaa atattaaaga aaatcctgaa ttgtttgtcg gaattgagtt ggagtatcct
      961 gttgcaagtt tagaagggga tgctacagat gttgaagtta taaaggatct atttcattat
     1021 ttagtttcta ctttggatct caccgtagca aaggtagatg attttggcaa tctgatccag
     1081 ttagtagatc cgataagtca ggatgctatt ttatttgaag tttcctatac aacgattgag
     1141 tttgcatttg gtaaggctga aacgattcaa gaggtcgaaa atcgtttcaa taattatatg
     1201 aatgtaattc agagaaagtt agctgaatca aatcatgcta ttgttggctg tggtatccat
     1261 cccaactggg ataaaaatga gaattgtcca gtggcttatc cacgctatca gatgttgatg
     1321 gattatttga atttgagtag aaatattatt aaatcagatt tacatcattt ccctgaatat
     1381 ggtactttta tctgtgggag ccaggttcag ctggatattt caaaaaccaa ctacttgcgg
     1441 gtgattaatg cttttactca aattgaagcg gctaaggctt atttatttgc aaactctgag
     1501 ttttcgggtg cggattggga tacgaaaatt tcaagggata ttttctggga agaatctatg
     1561 catggtatct atccagagaa tgttggggtc aatgctagac tccttaatga tgaagctgat
     1621 ttttttgact atctaaatca ttctgcgatt tttactgcgg aacgtgatgg gcagacctat
     1681 tatttttatc ctattcaggc tggggactat ttggctacgc ctgaaatcca agcatttgct
     1741 ctgaatgggg atgaggttat tatttacccc caagagaagg attttgaaac tcatcgtagt
     1801 taccagtacc aagacttaac gactcgagga acagttgagt ttcgtagtgt gtgtacacag
     1861 ccacttgata ggacttttgc ttctgcagct tttcacttgg gattattggt taatttagac
     1921 aagttagaag cttacttaga aacagcacct ttctttaaag tatttggtta tgattacaag
     1981 tttttaagga gacaattttc taagaaaaat cttacagatg aggaagaaac tatgattatt
     2041 gaattttcca aagacttact cctactagct gaggagggac tagtggtgag aaataaggaa
     2101 gaaatgacct atttacagcc tttgagagaa gaattgagcc tataatttct cttataaagg
     2161 gagaattttc tgaaaaatca tgatataatg gacgagacta tagataaagg atagagagta
     2221 atgacattag tttatcaatc aacgcgtgat gccaacaata cagtaactgc cagccaagca
     2281 attttgcaag gtttggcgac ggacggcggt ttgtttacac cggttactta tccaaaggta
     2341 gatttgaact ttaacaaatt gaaagatgct tcttaccagg aagttgctaa gctagttttg
     2401 tcagcatttt tagatgactt tacagctgag gagttggact actgtatcaa caatgcctac
     2461 gatagcaaat ttgatactcc agctattgca ccattagtga aattagatgg gcaatacaat
     2521 ttggaacttt tccatggttc aacgattgcc tttaaggata tggccttgtc tattttgcca
     2581 tactttatga cgactgctgc taagaaacat ggtttggaga acaagattgt tatcttgaca
     2641 gcgacatctg gtgacacggg gaaagctgct atggcggggt ttgcggatgt gcctggtact
     2701 gagattatcg tcttttatcc aaaggatggt gtcagcaaga ttcaagagtt acaaatgacc
     2761 actcaaactg gcgacaatac tcatgttatt gctattgatg gtaactttga cgatgcgcaa
     2821 acaaatgtga agcacatgtt taacgacgtg gctcttcgtg aaaaattgac taccaacaag
     2881 ttgcaatttt catcagctaa ctctatgaac attggtcgtc tggtgccaca aattgtttat
     2941 tatgtttatg cttacgctca attggtcaag actggtgaga tcgtggctgg tgataagatt
     3001 aacttcacag taccaacagg aaactttgga aatatcttgg ctgcctttta tgccaaacaa
     3061 atcggtctcc cagttggtaa attgatctgt gcttcaaatg acaacaatgt tttgacagac
     3121 ttcttcaaga cacgtgtcta tgacaagaaa cgtgagttta aggtaacaac cagcccatct
     3181 atggatatct tggtatcttc aaacttggag cgtttgattt tccatctttt ggggaatgat
     3241 gcggttaaga cggctgaact catgaatgct ttgaatagcc aaggtcaata tgagttgact
     3301 aattttgatg cagagatttt ggacctcttt gcagctgaat atgcgactga ggaagaaact
     3361 gcggcagaaa tcaagcgtgt ttatgagtca gattcttata tcgaggatcc tcatacagcg
     3421 attgcctcag cagtgtatag aaaataccag gcgactactg gagatgcgac taagacagtg
     3481 attgcttcaa cagctagtcc ctacaagttc ccagtagttg cagtagaagc gctaacaggg
     3541 aaagttggct tgactgattt tgaagctttg gctcaattac atgaaatctc aggcgttgca
     3601 gtgccaccag cagttgatgg gcttgagaca gctcctgttc gtcacaagac aatagtggca
     3661 gctgctgaca tgcaagtagc ggttgaggct tatttaggac tttaagatag agggagtaaa
     3721 ctcggttggg aaaccaactg agtttctttt catcaggagg agagattgtt taagaaaaat
     3781 aaagacattc ttaatattgc attgccagct atgggtgaaa actttttgca gatgctaatg
     3841 ggaatggtgg acagttattt ggttgctcat ttaggattga tagctatttc aggggtttca
     3901 gtagctggta atattatcac catttatcag gcgattttca tcgctctggg agctgctatt
     3961 tccagtgtta tttcaaaaag catagggcag aaagaccagt cgaagttggc ctatcatgtg
     4021 actgaggcgt tgaagattac cttactatta agtttccttt taggattttt gtccatcttc
     4081 gctgggaaag agatgatagg acttttgggg acggagaggg atgtagctga gagtggtgga
     4141 ctgtatctat ctttggtagg cggatcgatt gttctcttag gtttaatgac tagtctggga
     4201 gccttgattc gtgcaacgca taatccacgt ctgcctctct atgttagttt tttatccaat
     4261 gccttgaata ttcttttttc aagtctagct atttttgttc tggatatggg gatagctggt
     4321 gttgcttggg ggacaattct gtctcgtttg gttggtcttg tgattttgtg gtcacaatta
     4381 aaactgcctt atgggaagcc aacttttggt ttagataagg aactgttgac cttggcttta
     4441 ccagcagctg gagagcgact tatgatgagg gctggagatg tagtgatcat tgccttggtc
     4501 gtttcttttg ggacggaggc agttgctggg aatgcaatcg gagaagtctt gacccagttt
     4561 aactatatgc ctgcctttgg cgtcgctacg gcaacggtca tgctgttggc ccgagcagtt
     4621 ggagaggatg attggaaaag agttgctagt ttgagtaaac aaaccttttg gctttctctg
     4681 ttcctcatgt tgcccctgtc ctttagtata tatgtcttgg gtgtaccatt aactcatctc
     4741 tatacgactg attctctagc ggtggaggct agtgttctag tgacactgtt ttcactactt
     4801 gggaccccta tgacgacagg aacagtcatc tatacggcag tctggcaggg attaggaaat
     4861 gcacgcctcc ctttttatgc gacaagtata ggcatgtggt gtatccgcat tgggacagga
     4921 tatctgatgg ggattgtgct tggttggggc ttgcctggta tttgggcagg gtctctcttg
     4981 gataatggtt ttcgctggtt atttctacgc tatcgttacc agcgctatat gaacttgaaa
     5041 ggataggaaa tgcaaaaaac agcttttatt tgggatttag acgggacttt attggactct
     5101 tacgaagcga ttttatcagg gattgaggag acttttgctc tgttttctat tcgttatgat
     5161 aaggagaagg tgagagagtt tatcttcaag tattcggtgc aagatttgct tgtgcgggtg
     5221 gcagaagata gaaatctgga tgttgaggtg ctaaatcagg tgcgtgccca gagtctggct
     5281 gagaaaaatg ctcaggtagt tttgatgcca ggtgcgcgtg aggtgctagc ttgggcagac
     5341 gaatcaggaa ttcagcagtt tatatatact cataagggga acaacgcttt taccattctc
     5401 aaggacttgg gggtggaatc ctattttaca gagattttaa ccagtcagag tggctttgtg
     5461 cggaagccaa gtccagaagc ggctacctat ctgctagata agtatcagtt gaattctgat
     5521 aatacttatt atatagggga tcgaactctg gatgtggaat ttgcccagaa tagtgggatt
     5581 caaagcatca actttttaga gtctacttat gaagggaatc acaggattca agcgttagca
     5641 gatatttccc gtatttttga gactaagtga taaaaagatt gtgtcagttt tgtgacagag
     5701 acctaacaaa ctatttcaag taacctagtt tgttacaagg aatagacagt tctgttaaat
     5761 aggcccgaga gggctttttt tctacatttt ttgtgttatg atagacaggt actcatttga
     5821 aaggaatttg aaagaatgaa gaaaagaatg ttattagcgt caacagtagc cttgtcattt
     5881 gccccagtat tggcaactca agcagaagaa gttctttgga ctgcacgtag tgttgagcaa
     5941 atccaaaacg atttgactaa aacggacaac aaaacaagtt ataccgtaca gtatggtgat
     6001 actttgagca ccattgcaga agccttgggt gtagatgtca cagtgcttgc gaatctgaac
     6061 aaaatcacta atatggactt gattttccca gaaactgttt tgacaacgac tgtcaatgaa
     6121 gcagaagaag taacagaagt tgaaatccaa acacctcaag cagactctag tgaagaagtg
     6181 acaactgcga cagcagattt gaccactaat caagtgaccg ttgatgatca aactgttcag
     6241 gttgcagacc tttctcaacc aattgcagaa gctccaaaag aagtagcatc aagttcagaa
     6301 gttacaaaga cagtgattgc ttctgaagaa gtggcaccat ctacgggcac ttctgtccca
     6361 gaggagcaaa cggccgaaac aagcagtgca gttgcagaag aagctcctca ggaaacgact
     6421 ccaggtgaga agcaggaaac acaagcaagc cctcaagcag catcagcagt ggaagcaact
     6481 acaacaagtt cagaagcaaa agaagtagca tcatcaaatg gagctacagc agcagtttct
     6541 acttatcaac cagaagagac gaaaataatt tcaacaactt acgaggctcc agctgcgccc
     6601 gattatgctg gacttgcagt agcaaaatct gaaaatgcag gtcttcaacc acaaacagct
     6661 gcctttaaag aagaaattgc taacttgttt ggcattacat cctttagtgg ttatcgtcca
     6721 ggagacagtg gagatcacgg aaaaggtttg gctatcgatt ttatggtacc agaaagttca
     6781 gaattagggg ataagattgc ggaatatgct attcaaaaca tggccagccg tggcattagt
     6841 tacatcatct ggaaacaacg tttctatgct ccattcgata gcaaatatgg gccagctaac
     6901 acttggaatc caatgccaga ccgtggtagt gtgacagaaa atcactatga ccacgttcac
     6961 gtttcaatga atggataaac ccgacttggt aacatcattt tgacgaatga gatctagctt
     7021 tcgtgatagg aagcgattct cgttcgtttt ttctttgtca tactcttcga aaatctcttc
     7081 aaaccacgtc agttttatct gaaacctcaa agctgtgctt tgagcaacct gcgactagct
     7141 ttctagttta ctctttgatt ttcattgagt atcaatttga atggaaaatg gaaagttatt
     7201 atcttgtaat aatccaagca acattcttgc aatctatttt actttatatc acaattgatt
     7261 ggtcaactat tgataagtca atggatagga ggaagaaatg atagagattc aagatttact
     7321 gtatcaactc cgcttgtctg agcaagcgag tacgcaattg tttgaaaaag gcttgggatt
     7381 agtttgacac ggtatcagat tttactgttt ttgctggagc attctccttg taaccaaatg
     7441 gcggttcagg agcgtttgaa aattgatcag gctgctttga cacggcattt caagattttg
     7501 gaaacggaag gtttggtgga gcgtcatcgt aatcctgaaa atcagcggga agtgttggta
     7561 gaggctgcga agtatgccaa ggagcagtta gtggtgaatc cccctctgca acatatcaag
     7621 gttaaggaag agatggaaag tatcttaaca gagtttgaga gaacagaact cagccgttta
     7681 ttaaataaat tggttttggg tattgaaaat atagaaattt aaggagaaat agatgtcaat
     7741 tattttaaca acgatcgttg ctttggagca tttttacatt ttttatttgg aaagtattgc
     7801 cacgcaatca gatgcgacta gtcgtgtatt taatatggaa aaggaagaat tggctcatcc
     7861 gtcagtaagt tcattgttca aaaatcaagg aatttataag gctctgctag gagtctttct
     7921 cttgtatgtc atttatttct cacagaattt agaaattgtg actatttttg tcttatttgt
     7981 gattggtgct gcgacttacg gctctttaac agcggataaa aaattatttt gaagcaaggt
     8041 ggatcagcta ttttggcctt gattagtatt ttactcttta aatacacttg aaggttgatt
     8101 ctaatctcgc taatcctttt taatccagaa taagggaaat atgttatact tgtttttaag
     8161 aaaaaagtct cattgaattg gttttgagga gttagaaatg aaagtattag tgacaggttt
     8221 tgagcccttt tgaggccatt aaaggtttac cagctgaaat ccatggtgct gaggtccgtt
     8281 agctagaggt gccgacagtt tttcacaaat ctgctcaagt attggaagaa gagatgaatc
     8341 gttatcaacc tgactttgtc ctttgtattg ggcaagctgg tggaagaact agtttgacac
     8401 ctgaacgagt ggccattaat caagacgatg cacgcatttc tgataacgaa gataatcaac
     8461 cgattgaccg tcccattcgc ccagatggtg cttcggccta ctttagtagt ttgccgatta
     8521 aagcgatggt tcaagctata aaaaagaggg cttaccggcc tctgtttcca atacggcagg
     8581 gacttttgtc tgcagccatt tgatgtatca ggctctctat ttggtagaaa agaaatttcc
     8641 atatgttaag gcaggtttta tgcatattcc ttatatgatg gaacaggtgg tgaacagaca
     8701 gactattcca gctatgagtt tagtggatat tcggcgaggg atagaagcag caatcggcgc
     8761 tatgatagaa catggagatc aggaactcaa gttggtaggc ggagaaactc attgatagaa
     8821 aaaagcttga ggggaaaaac cttcaagctt ttggacgttt tcgagccaat actgctcggt
     8881 aaaacataat tttagtgcat tggatataag gtaggagtga aaaactagca atgccaaagg
     8941 taatccaatt gaggaagtac caaggaagaa gctgtaaatc taggacaaag cgctggaact
     9001 tgtagccctt cataaaggaa cggctagttt ttaggattcg tcttggtggg acctgtccta
     9061 ggtctagact ataacagaga agaaattcca cctgtgaata ggcataatac tgtggaatat
     9121 agaggatatt tcctacaatg atcaagatga gacttgcaag aaagtagagt ccaaagacca
     9181 tgaggaaacg ctcggtttca actgatgaga gatctagatt tggaaactca ggatgtaggg
     9241 tgacgaattt tttggctaaa aagctactat aaaagaggag gtaaatccca agtaaattag
     9301 ggatactcca taaaaagaga tagaaacgtt tgagaagtag ggtcaaaaag gtttgagaaa
     9361 agcgctcctc atcaaagaga gctaggctgt tttttacaga tggctccgtt ttagaatctt
     9421 tcatgagtgt cagtgttgca tagacggaac tggtcaaaag aatagtcccg ataaaggaga
     9481 ctagtagagg aaagaggtag gcttgaagta tttggccaag tatgctgaaa aatggctgtt
     9541 ctaaaacagt cccgtggatc cgagataagg gattaagaaa actagataag atgaccagca
     9601 tactgggaag gatatagagg agaaagagac ggggggtgtc agcctgaaaa tgttttgact
     9661 cctgacgaat tgtttttaaa tcaatttttg gatagttcat tctcttatta taccatagtt
     9721 cttatacata gttcgtgaca gttcctactt tttttgataa aatcatacag tgtgtccttg
     9781 ggcacactgt atgaactggg actgtctttc ccagcttcgg aggtaaaaaa tgtcagattc
     9841 accaatcaaa tatcgtttga ttaagaaaga aaaacacaca ggagctcgtc tgggagaaat
     9901 catcactccc cacggtacct ttccgacacc tatgtttatg ccagttggga cacaagccac
     9961 tgtcaaaact cagtcacctg aagaattgaa ggagatgggt tcgggaatta tcctatcaaa
    10021 cacctatcat ctctggcttc gccctggaga tgaactcatt gcacgcgctg gtggtctcca
    10081 caagttcatg aattgggacc agcctatctt gacagatagt ggtggttttc aggtttattc
    10141 tttagcagat agccgtaata tcacagaaga aggagtaacc tttaaaaatc atctaaatgg
    10201 ttctaagatg ttcctatccc cagaaaaagc catctctatt cagaataatc tgggttcaga
    10261 catcatgatg tcctttgatg aatgtcctca gttttatcaa ccttatgact acgttaagaa
    10321 atcgatcgag cgtaccagcc gttgggctga gcgtggtttg aaggctcacc gtcgtccaca
    10381 tgaccaaggt ttgtttggaa ttgtgcaagg tgcaggattt gaagaccttc gccgccaatc
    10441 agctcatgat cttgtcagca tggatttctc aggctactct atcggtggtt tggcagtggg
    10501 agaaacccat gaagagatga atgcggtctt ggactttaca actcaactgc tgcctgaaaa
    10561 taaacctcgt tatctgatgg gtgtgggagc gccagatagc ttgatcgatg gggtcattcg
    10621 tggggtggat atgtttgact gtgtcttacc gactcgaatt gctcgtaacg ggacttgtat
    10681 gaccagtcaa ggacgtttgg ttgtgaaaaa tgcccagttt gctgaggact ttacgccact
    10741 ggatcctgag tgtgattgct acacatgtaa taactataca cgcgcttacc ttcgtcacct
    10801 gctcaaggct gatgaaacct ttggtatccg cttgactagc taccacaatc tttacttctt
    10861 gcttaacctg atgaagcaag tgcgacaagc catcatggat gacaatctct tggaattccg
    10921 tgagtatttt gtggaaaaat atggctataa taagtcagga cgtaatttct aaaatggaat
    10981 tgatataaaa aaatcctaag ttttctctta ggatttttct tctttttttg atagaataaa
    11041 gtgtacaatg aaaggaagaa taaactcgta tgcgcattaa atggttttcc ttgattagga
    11101 ttataggttt acttttggta ctcttgtatc acttctttca gacgatcttt cctggaggat
    11161 ttttcggggt agatgtcttt ttcacatttt caggtttcct gattacagct ctactcattg
    11221 aagaattttc taagaacaat gagattgatt tgataggatt ttttagaaga cgcttttatc
    11281 ggattgtgcc acctgtggtt ttgatggtct tggtgaccat gccttttact ttcttggttc
    11341 gccaagacta tgttgctgga attggtggcc agattgcggg cgtcttaggc tttatgacca
    11401 acttctatga actcctaaca ggtgggagtt atgaatctca gttcattcct catttgtttg
    11461 ttcataattg gagtttggca gttgaggttc actactatat tctttgggga ttggcagttt
    11521 ggttcttatc caaacaagct aaatcaaatg gtcagttgaa ggggatggtc tttctcttat
    11581 ctgctgttgc cttcttgatc agtttcttct ccatgtttat tggtagtttt ctagtgacct
    11641 cttattcctc tgtttatttc tccagtttaa ctcatgtcta tccattcttt ttaggaagta
    11701 tgttagcaac tattgtaggc gttcgtcaga cgacttccct cgtcaagcag ttggataaaa
    11761 tctgggattt acgaaagact ttggtagttt ttggaggagg ctttggtttc ctagttcttt
    11821 tgactttctt tgtcaaattc acttatcttt ttgcctatct tatcggcttc ttacttgcca
    11881 gtcttgcagc tcttgccatg attctggcgg cgcgtgtctt acatgaaaag acacatcata
    11941 tacaggagtc gaagattatc agctttttag cggatactag ctatgcggtt tatcttttcc
    12001 attggccttt ctatatcatt ttctcacagt tgacatcaaa tcttcttgct gtattactga
    12061 ctctgatttg ttcttatggc tttgccagtc tgtcatttta tgtattggaa ccttggattg
    12121 caggcaagaa cacacctatt gtccaaaccc ttcgtcccct gccttatatt cacgcaattc
    12181 ttgcagcagg tacaggaatc ttgaccatca ttgtctgcac ggtgaccttg ttggcaccac
    12241 aagtgggagc gtttgagaca gacttgactg tcaatggctt gaagcaagct gcaacaaata
    12301 ttggccagac caaggtgatg gcagaacggg cagatgcaaa cagtttggga attgctgatg
    12361 gcactatgtt aattggtgac tcagtggctt taagggcaaa tacagcacta cagacagctc
    12421 ttcctggagc acagattaac gcgcaggtca gcgtaacaac caagaccgca aatgaaatca
    12481 tgctaaataa tagccagaat aaatttttac ctaagacggt ggtcattgcg actggggtaa
    12541 ataatcctga gaattacaag gatgactggg acagtatcgt gaaaaatctt cctaagggac
    12601 accatatgat tttggtgact ccttatgagg gagataagac aaaagagacc tatgccatcg
    12661 ttgagaaggc tgctgcctat atgagagaat tggcagagaa gacaccttac attacgatag
    12721 cagattggaa tcaagttgcg aaagagcatc cagaaatttg ggctggaaca gaccaggttc
    12781 atttcgggag tgagagtagc actatcgaag caggagcaaa attgtatgca gatacgattg
    12841 ccacagcttt gcagacagct caagacaagc cggttaaatc aaaataactt gtattaaaaa
    12901 agagaagagt tggagaaatc cagctctttt aaaatatctc caaaaaatag gtctatacca
    12961 tttacaaata aaaaagaaag gtttataatg taattgacat aataaattgt agaatcaatc
    13021 ttttaaggag gttaacatta tgcctaacta tattaaagcg gatcagtttt tctacccaca
    13081 cggagttcgt cgaggtggtt acttggaact tgtggacggc aagtttggga aacatgtaga
    13141 gcagattcct gaaggggctg aggtgattga ctatacaggt tatagcattg ccccaggtct
    13201 tgtggatact catattcatg gatatgcagg tgtagatgtg atggacaaca acattgaagg
    13261 tacattgcat actatgagtg aaggacttct tagtaccggt gttaccagtt tcttacccac
    13321 aactttaaca gccacttatg agcaattgct tgcagtcact gaaaatcttg gaaaccatta
    13381 taaagaagca acaggtgcta agattcgtgg gatttattat gaaggtccat atttcacaga
    13441 aacttttaag ggggcacaaa atccaactta tatgagagac ccgggtgttg aggagtttca
    13501 ttcttggcaa aaagcggcaa atggcttgct taataaaatt gcccttgcac cagaacgtga
    13561 tggggtggaa gactttgttc gtacagttac gggcgaaggt gtgacggttg ctcttggaca
    13621 ttcaaacgcg acttttgatg aagccaaaaa agcagtcgat gctggagcga gtgtttgggt
    13681 gcatgcctac aatggaatgc gtgggttgac tcaccgtgaa ttgggtatgg ttggagccat
    13741 gtaccaattg ccacatacct atgcagagtt gatctgtgat ggtcaccacg tagatccaaa
    13801 ggcttgcgaa attcttatca aacaaaaagg aacagaaaac atcgctctta tcacagactg
    13861 tatgacagct gggggattgg aagacggaga ttatatgttg ggagaattcc cagttgtcgt
    13921 tgcaaatgga actgcacgcc tcaaatcgac aggtaacttg gcaggttcta tcctcaaact
    13981 caaagatggt ttgaagaatg tggtcgaatg gggaattgcg aatccgcatg aagcagtcat
    14041 gatggccagc ttcaacccag ctaaatccgt tcacatcgat gacgtctgtg gccaaatccg
    14101 tgaaggctac gacgctgact tcatcgtatt agataaagat ttggaattgg tagcaaccta
    14161 cctagatggc gtaaaacgtt atcaagcata agagagaaag cagaagttag agactaactt
    14221 ctgctttttt atgcagggta ctttactggt aaataaaaag ttaaaaaaat cacaaaaaaa
    14281 gcttgaagaa acaaagaaaa aggcttacaa ttgaactata aatattacaa ataaaaaaac
    14341 ggaggagtgc tttatgaaag cctatactta tgttaaacca ggacttgctt cttttgttga
    14401 tgtagacaaa ccagttattc gcaagccaac agacgctatt gtgcgtattg taaaaaccac
    14461 tatttgtgga acagacctcc atattatcaa aggggatgtt cctacttgcc aaagtggtac
    14521 cattcttggc cacgaaggga ttgggattgt tgaagaagtt ggggaaggag tttccaactt
    14581 caaaaaaggt gacaaggtct tgatttcttg cgtctgtgcc tgtggtaaat gctactactg
    14641 taaaaaagga atttatgctc actgtgaaga cgaagggggt tggattttcg gtcacttgat
    14701 tgatggtatg caggctgaat atctacgtgt ccctcatgca gataatactc tttaccatac
    14761 tccagaagac ttgtcagatg aagctttggt tatgctgtca gacattctgc ctactggata
    14821 tgaaattggt gtcttaaaag ggaaagtaga acctggttgc agcgtagcca ttattggttc
    14881 aggtccagtt ggattggctg ctcttttaac agcccaattc tattcaccag ctaaattgat
    14941 tatggtagac ctagacgata accgcttgga aactgcccta tcattcggtg cgactcataa
    15001 ggttaattct tcagaccctg aaaaagccat taaagaaatt tatgatttga cagatggtcg
    15061 tggtgtggat gtcgctatcg aagctgttgg tattcctgca acatttgatt tctgtcaaaa
    15121 gattatcggt gtagacggaa cggttgccaa ctgtggtgtg catggtaaac cagttgaatt
    15181 cgatttagat aaactttgga ttcgcaacat caatgtaaca actggtttgg tatctacaaa
    15241 tacgactcca caattgttga aagcacttga aagtcataag attgaaccgg aaaaattggt
    15301 aactcactat ttcaaactca gtgaaattga aaaagcctac gaagtcttca gtaaggcagc
    15361 agaccaccat gccattaagg tcattatcga aaacgatatc tcagaagcct aagtagtaaa
    15421 aatatttttg tacataagta aatagaaatt cagtcatcca tcagatggct ggatttttta
    15481 tcaaaaaatt aagaaatgag catatttctt tccttgtctg gcggaattgg ttataatata
    15541 cggtacaaag gaatgaatga atatgtatcg tgttatagaa atgtacggag attttgaacc
    15601 gtggtggttc ttagaaggtt gggaagaaga tattgtagca agtagaaaat ttgaccagta
    15661 ttatgatgct ctcaaatact acaaaacttg ctggtttaga ttggaacaag aatcgcctct
    15721 ttataaaagt agaagcgact tgatgaccat tttttgggac ccggaagacc aacgctggtg
    15781 tgatgaatgt gatgagtatt tacaacaata ccattctttg gctcttttgc aggatgagca
    15841 ggttatccca gacgaaaaac tacgctcagg ctatgaaaaa caaaccagtc aggaaaggaa
    15901 tcgttcttgc cgtatgaaat taaaatagag aaaagtaact tttttggagt tgcttttttt
    15961 atttttctaa ctctttgcga atagtatagg tgaggaggta agtatggttc aagaaattgc
    16021 acaagaaatc attcgttcag ctcggaaaaa agggacgcag gatatctatt ttgtccctaa
    16081 gttagacgcc tatgagcttc atatgagggt aggagacgag cgctgtaaaa ttggtagcta
    16141 tgattttgaa aagtttgcag ccgttatcag tcactttaag tttgtggcgg gtatgaatgt
    16201 gggagaaaaa agacgtagtc aactgggttc ctgtgattat gcctatgacc ataagatagc
    16261 gtctctacgt ttatctactg taggcgatta tcgggggcat gagagtttgg ttatccgttt
    16321 gttgcacgat gaggagcagg acctgcattt ttggtttcag gatattgaag aattaggcaa
    16381 gcagtacagg caacggggac tctatctttt tgctggtccg gttgggagtg gtaagacgac
    16441 cttgatgcat gaattgtcca agtcactctt taaaggacag caagttatgt ccatcgaaga
    16501 tcctgtcgaa atcaagcagg acgacatgct tcagttgcag ttgaacgaag caatcggcct
    16561 aacctatgaa aatctaatca aactttcctt gcgtcatcga ccagatctct tgattatcgg
    16621 agaaattcgt gacagcgaga cggcgcgtgc agtggtcaga gctagtttga caggtgcgac
    16681 agtcttttca accattcacg ccaagagtat ccgaggtgtt tatgagcgtc tgctggagtt
    16741 gggtgtgagt gaagaagaat tggcagttgt tctgcaagga gtctgctacc agagattaat
    16801 cgggggagga ggaatcgttg actttgcaag cagagattat caagaacacc aagcagccaa
    16861 gtggaatgag caaattgacc agcttcttaa agatggacat atcacaagtc ttcaggctga
    16921 gacggaaaaa attagctaca gctaagcaaa aaaatatcat caccctattt aacaatctct
    16981 tttctagcgg ttttcatctg gtggagacta tctccttttt agataggagt gctttgttgg
    17041 acaagcagtg tgtgacccag atgcgtgtgg gcttgtctca ggggaaatca ttctcagaaa
    17101 tgatggaaag tttgggatgt tcaagtgcta ttgtcactca gttatcccta gctgaagttc
    17161 atggcaatct ccacctgagt ttgggaaaga tagaagaata tctggacaat ctggctaagg
    17221 tcaagaaaaa attgattgaa gtagcgacct atcccttgat tttgctgggt tttcttctct
    17281 taattatgct ggggctacgg aattacctgc tcccacaact ggatagtagc aatattgcca
    17341 cccaaattat cggtaatctg ccccaaattt ttctaggcat ggtagggctt gtttccgtgc
    17401 ttgccctttt agcactcact ttttataaaa gaagttctaa gatgagtgtc ttttctatct
    17461 tagcacgcct tccctttatt ggaatctttg tgcagaccta cttgacagcc tattatgcac
    17521 gtgaatgggg gaatatgatt tcacagggaa tggagttgac gcagattttt caaatgatgc
    17581 aggaacaagg ttcccagctc tttaaagaag tcggtcaaga tctggctcaa accctgaaaa
    17641 atggccgtga attttctcag acgataggaa cctatccttt ctttaggaag gaattgagtc
    17701 tcatcataga gtatggggaa gttaagtcca agctgggtag tgagttggaa atctatgctg
    17761 aaaaaacttg ggaagccttt tttacccgag tcaaccgcac catgaatttg gtgcagccac
    17821 tggtttttat ctttgtggca ctgattatcg ttttacttta tgcggcaatg ctcatgccca
    17881 tgtatcaaaa tatggaggta aatttttaaa atgaaaaaaa tgatgacatt cttgaaaaaa
    17941 gctaaggtta aagcttttac attggtggag atgttggtgg tcttgctgat tatcagcgtg
    18001 cttttcttgc tctttgtacc taatctgacc aagcaaaaag aagcagtcaa tgacaaagga
    18061 aaagcagctg ttgttaaggt ggtggaaagc caggcagaac tttatagctt agaaaagaat
    18121 gaagatgcta gcctaagaaa gttacaagca gatggacgca tcacggaaga acaggctaaa
    18181 gcttataaag aataccatga taaaaatgga ggagcaaatc gtaaagtcaa tgattaaggc
    18241 ctttaccatg ctggaaagtc tcttggtttt gggacttgtg agtatccttg ccttgggctt
    18301 gtccggctct gtccagtcca ctttttcagc ggtagaggaa cagattttct ttatggagtt
    18361 tgaagaactc tatcgggaaa cccaaaaacg cagtgtagct agtcaacaaa agactagtct
    18421 gaacttggat gggcagatga ttagcaatgg cagtcaaaag ttgacagttc ctaaaggaat
    18481 tcaggcacca tcaggccaaa gtattacatt tgaccgagct gggggcaatt cgtccctggc
    18541 taaggttgaa tttcagacca gtaaaggagc gattcgctat caattatatc taggaaatgg
    18601 aaaaattaaa cgcattaagg aaacaaaaaa ttagggcagt gattttactg gaagcagtag
    18661 tcgctctagc tatctttgcc agcattgcga ccctcctttt gggacaaatt caaaaaaata
    18721 ggcaagagga agcaaaaatc ttgcaaaagg aagaagtctt gagggtagct aagatggccc
    18781 tgcagacggg gcaaaatcag gtaagcatca acggagttga gattcaggta ttttctagtg
    18841 aaaaaggatt ggaggtctac catggttcag aacagttgtt ggcaatcaaa gagccataag
    18901 gtcaaggctt ttaccttgtt agaatccctg cttgccctca ttgtcatcag tgggggatta
    18961 ctcctttttc aagctatgag tcagctcctc atttcagaag ttcgctacca gcaacaaagc
    19021 gagcaaaagg agtggctctt gtttgtggac caacttgagg tagaattaga ccgttcgcag
    19081 ttcgaaaaag tagaaggcaa tcgcctatac atgaagcaag atggcaagga catcgccatc
    19141 ggtaagtcaa agtcagatga tttccgtaaa acgaatgctc gtggtcgagg ttatcagcct
    19201 atggtttatg gactcaaatc tgtacggatt acagaggaca atcaactggt tcgctttcat
    19261 ttccagttcc aaaaaggctt agaaagggag ttcatctatc gtgtggaaaa agaaaaaagt
    19321 taaggcaggt gttctcctct acgcagtcac catagcagcc atctttagtc ttttgttgca
    19381 attttatttg aaccgacaag tcgcccacta tcaagactat gctttgaata aagaaaaatt
    19441 ggttgctttt gctatggcta aacgaaccaa agataaggtt gagcaagaaa gtggggaaca
    19501 gttttttaat ctaggtcagg taagctatca aaacaagaaa actggcttag tgacgagggt
    19561 tcgtacggat aagagccaat atgagtttct gtttccttca gtcaaaatca aagaagagaa
    19621 aagagataaa aaggaagagg tagcgaccga ttcaagcgaa aaagtggaga agaaaaaatc
    19681 agaagagaag cctgaaaaga aagagaattc atagtcaatt caactataat gcgttgaatc
    19741 cagaatagtc cactgtagtt tctagaaaat tgctggaaat ggatgttaag ctccaattca
    19801 tttgtttata tcttatttca gtttactata ctttgtgcta aattaaagat atgaaacatg
    19861 attttaacca caaagcagaa actttcgatt cccctaaaaa tatcttcctc gcaaacttgg
    19921 tatgtcaagc agccgagaaa cagattgatc ttctatcaga caaagaaatt ttagatttcg
    19981 gtggtggcac gggtctatta gccttgcccc taacccctag ccaagcaggc taagtcagtc
    20041 actcttgtag acatttctga gaaaatgttg gagcaagctc gtttgaaagt ggagcagcaa
    20101 gcaatcaaga atatccagtt tttggagcaa gatttaccga aaaatccctt ggagaaagag
    20161 tttgattgcc ttgctgttag tcgggttctt catcatatgc ctgatttgga tgcggctctc
    20221 tcactgtttc atcaacattt gaaggaagat gggaaactca tcattgctga ttttaccaag
    20281 acagaagcta atcatcatgg atttgattta gctgaactgg aaaacaagct aattgagcat
    20341 ggtttttcat ctgtgaatag tcagattctc tatagcgctg aagacctgtt tcaaggaaat
    20401 cactcagaat tctttttaac agtagcccaa aaatcactcg cctagtcagg gagtgatttt
    20461 tctataagga tggaaaaaag aagggaaatt tgataagata ggaatatgga ttttgaaaaa
    20521 attgaacaag cttataccta tttactagag aatgtccaag ttatccaaag tgatttggcg
    20581 accaactttt atgacgcctt ggtggagcaa aacagcatct atctggatgg tgaaactgag
    20641 ctaaaccagg tcaaagacaa caatcaggcc cttaagcgtt tagcactacg caaagaagaa
    20701 tggctcaaga cctaccagtt tctcttgatg aaggctgggc aaacagaacc cttgcaggcc
    20761 aatcaccagt ttacaccaga tgccattgct ttgcttttgg tgtttattgt ggaagagttg
    20821 tttaaagagg aggaaattac tatcctcgaa atgggttctg ggatgggaat tctaggcgct
    20881 actttcttga cctcgcttga taaaaaggtg gattacttgg gaatggaaat ggatgatttg
    20941 ctgattgatc tggcagctag catggcagat gtaattggtt tgcaggctgg ctttgtccaa
    21001 ggagatgccg ttcgtccaca aatgctcaaa gaaagcgatg tggtcatcag tgacttgcct
    21061 gttggctatt atcctgatga tgccgttgcg tcgcgccatc aagttgcttc tagccaagaa
    21121 catacttacg cccatcactt gctcatggaa caagggctta agtacctcaa gtcagacgga
    21181 tacgctattt ttctagctcc gagtaatttg ttgaccagtc ctcaaagtga tttgttaaaa
    21241 gaatggctga aagaagaggc gagtctggtt gctatgatta gtctgcctga aaatctcttt
    21301 gctaatgcca aacaatctaa gactattttt atcttacaga agaaaaatga aatagcagta
    21361 gagccttttg tttatccact tgctagcttg caagatgcaa gtgttttaat gaaatttaaa
    21421 gaaaattttc aaaaatggac tcaaggtact gaaatataaa atagattttg ttataatagt
    21481 tgaaaacgct taaaaagggg tatcatgtta tgacaaaaac aattgcaatc aatgcaggaa
    21541 gttcaagttt gaaatggcaa ttatacttaa tgccagagga aaaagtgtta gccaaaggtt
    21601 tgattgaacg tatcggtttg aaagattcaa tttcaactgt aaaatttgac ggccgttctg
    21661 aacaacaaat tttggatatt gaaaatcata cacaagccgt taaaatttta ttggatgact
    21721 tgattcgttt cgatattatc aaggcttatg acgagattac aggtgttgga catcgtgttg
    21781 ttgctggtgg agaatatttc aaagaatcaa cagttgttga gggagatgtt ttagaaaaag
    21841 ttgaagagtt gagtttgttg gctcctctac acaacccggc caatgcagca ggtgttcgtg
    21901 ccttcaagga attgttgcca gacattacca gtgtagttgt ttttgatact tccttccaca
    21961 caagtatgcc agagaaagct tatcgctacc ctctaccaac aaaatattac acagaaaaca
    22021 aggttcgtaa atacggtgct catggtacaa gtcaccagtt tgtagcagga gaagctgcaa
    22081 aactcttggg acgtccatta gaagacttga agttaattac ctgtcatatt ggtaacggag
    22141 gctcaattac agctgtgaaa gccggcaaat ctgtagacac ttctatgggg ttcactcctc
    22201 ttggtggtat tatgatggga acgcgtacag gggatattga tccagctatc attccttatt
    22261 taatgcaata tacagaggat tttaacacac cagaagatat cagtcgtgtt cttaaccgtg
    22321 aatcaggtct tttgggagtt tctgctaatt ctagcgatat gcgcgatata gaagcagctg
    22381 tagcagaagg gaatcacgag gctagcttgg cttatgaaat gtatgttgac cgtatccaaa
    22441 aacatatcgg tcagtacctt gcagtgctaa atggagcaga tgccattgtt ttcacagcag
    22501 gtgtcggtga aaatgcagag agtttccgtc gtgatgtaat ctcagggatt tcgtggtttg
    22561 gttgtgatgt tgatgatgaa aagaatgtct ttggcgttac aggagacatc tcaacagagg
    22621 cagctaaaat ccgtgtcttg gttattccaa cagatgaaga attagtcatt gcccgtgacg
    22681 ttgaacgctt gaaaaaataa gtgaaactaa aaaaatattc aatacaagga gttgggaaag
    22741 ttatttttcc agcttctttt tctgatgaaa ttgtccaaaa ccttgctatg attggctttt
    22801 ttgaaaaata tggtataata gtagtaattt aatagatgga gttgagtttt gaagaaaaac
    22861 tttcgtgtaa aaagagagaa agattttaag gcgattttca aggaggggac aagttttgct
    22921 aatcgcaaat ttgtggtcta ccaattagaa aaccagaaaa accattttcg agtaggtcta
    22981 tcagttagca aaaaactggg gaatgccgtc actagaaatc aaattaagcg acggattcgg
    23041 catattatcc agaatgcaaa agggagtctg gtagaagatg tcgactttgt tgtcattgct
    23101 cgaaaaggag tcgaaacctt gggatacgca gagatggaga aaaatctact ccatgtatta
    23161 aaattatcaa agatttaccg ggaaggaaat gggagtgaaa aagaaactaa agttgactag
    23221 tttgctagga ctgtctctgt taatcatgac agcctgtgcg actaatgggg taactagcga
    23281 tattacagcc gaatcggctg atttttggag taaattggtt tacttctttg cggaaatcat
    23341 tcgcttttta tcgtttgata ttagtatcgg agtggggatt attctcttta cggtcttgat
    23401 tcgtacagtc ctcttgccag tctttcaggt gcaaatggtg gcttctagga aaatgcagga
    23461 agctcagcca cgcattaagg cgcttcgaga acaatatcca ggtcgagata tggaaagcag
    23521 aaccaaacta gagcaggaaa tgcgtaaagt atttaaagaa atgggtgtca gacagtcaga
    23581 ctctctttgg ccgattttga ttcagatgcc ggttattttg gccctgttcc aagccctatc
    23641 aagagttgac tttttaaaga caggtcattt cttatggatt aaccttggta gtgtggatac
    23701 aacccttgtt cttccgattt tagcagcagt attcaccttt ttaagtactt ggttgtccaa
    23761 caaagctttg tctgaacgaa atggcgctac gactgcgatg atgtatggga ttccagtctt
    23821 gatttttatc tttgcagttt atgcgccagg tggagtcgcc ctatactgga cagtgtctaa
    23881 tgcttatcaa gtcttgcaaa cctatttctt gaataatcca ttcaagatta tcgcagagcg
    23941 cgaggccgta gtacaggcac aaaaagattt ggaaaataga aaaagaaaag ccaagaaaaa
    24001 ggctcagaaa acgaaataaa taaggaggaa tctggtaatg gtagtattta caggttcaac
    24061 tgttgaagaa gcaatccaga aaggattgaa agaattagat attccaagaa tgaaggctca
    24121 tatcaaagtc atttctaggg agaaaaaagg ctttcttggt ctatttggta aaaaaccagc
    24181 ccaagtggat attgaagcga ttagtgaaac gactgttgtc aaagcaaatc aacaggtagt
    24241 aaaaggcgtt ccgaaaaaaa tcaatgattt gaacgagcct gtgaagacgg ttagtgaaga
    24301 aaccgttgac cttggtcatg tggttgatgc tattaaaaaa atagaggaag aaggtcaagg
    24361 tatttctgat gaagtcaagg ctgaaatctt aaaacatgaa agacatgcca gcactatctt
    24421 agaagaaact ggtcacattg agattttaaa tgaacttcaa atcgaggaag cgatgaggga
    24481 agaagcaggc gctgatgacc ttgaaactga gcaagatcaa actgaaaatc aagacttgaa
    24541 agagatgggc ttgaaggtcg agcaaagtta tgatattgcc caggtggcta cggatgtgac
    24601 tgcttatgtt caaacgatta tagatgacat ggatgttgag gctacacttt caaatgatta
    24661 taaccgtcgt agcatcaatt tgcaaattga tactaacgaa ccaggtcgta ttatcggcta
    24721 ccatggtaaa gtcttgaagg ccttgcaact gttggctcaa aattatcttt acaactgcta
    24781 ttcaagaacc ttctatatca ctattaatgt caatgattat gttgaacacc gtgcagaagt
    24841 cttgcagacc tatgcgcaaa aattggcgat tcgtgtttta gaagaagggc gcagtcatca
    24901 aacagatcca atgtcgaata gtgaacgcaa gattatccac cgtattattt cacgtatgga
    24961 tggcgtgacc agttactctg aaggtgatga gccaaatcgc tatgtcgttg tagatacaga
    25021 ataagtaaaa tcagggttga cctgattttt tgctagctag aggaggttaa actgatgttg
    25081 aataagataa gagactatct agacttttct ggtttgcagt accgtagtcc tgataaagcg
    25141 ggagcagagc gagagaagat gctggcgttc cgccacaaag gacaagaggc ccgaaaggct
    25201 tttacagaac tggccaaagc ctttcaagca agccatccag aatggcaact ccaacagact
    25261 agtcagtgga tgaatcaggc ccagcgtttg agaccacatt tttgggttta tctacagaga
    25321 gacggacaag tgacagaacc tatgatggcc ttacgtttgt atgggacatc tactgacttt
    25381 ggaatttctt tggaagtcag tttcatcgaa cgtaagaagg atgagcaaac actgggcaag
    25441 cagaccaaag ttttagacat tccaaccgtt aaagggattt attatctaac ctactctaat
    25501 ggtcaaagtc aacggtggga ggcgaatgaa gaaaagcgtc gtactttacg cgagaaggtg
    25561 agaagtcaag aagttcgaaa agttttagtg aaggtagatg ttcctatgac agaaaattcg
    25621 tctgaagaag aaatcgtaga aggcttattg aagtcttatt ctaaaattct tccctattat
    25681 ctagctacga gaaaataaga taatttgtaa aacatcataa atcatacagt ccaagagtga
    25741 acagtccgct gtgtaattct tggtcttttt gtttgcgctt tcgcattata taataaactt
    25801 acaaaaacaa ttcaaaagga gaacaattat ggaagtcgtt tcaagtgttc taaattggtt
    25861 ttctagcaat attttgcaga atcccgcatt tttcgtaggt ttattggtgt tgataggata
    25921 tgcacttttg aaaaaacctg cccatgacgt tttttcaggg tttgttaaag caacagtagg
    25981 gtatatgttg cttaacgtgg gtgctggtgg tttggttaca acctttcgtc caatcttagc
    26041 agctcttaac tacaaattcc aaattggtgc agcggttatc gacccttact ttggacttgc
    26101 tgcagtaaac aacaaaattg cagcagagtt tccagatttt gttggaactg caactacagc
    26161 tctattgatt ggttttggaa taaatatctt gctcgtagct cttcgaaaga ttacgaaggt
    26221 aagaaccctc tttattactg gtcacatcat ggtacaacaa gctgcaacag tatcttttat
    26281 ggttctattc ttagtaccac aattgcgcaa tgcttacggt acagcagcga ttggtatcat
    26341 ctgtggactt tactgggcag ttagttcaaa tatgactgtt gaggcaactc aacgcttgac
    26401 tggtggtggc ggatttgcga ttggtcacca acagcaattt gcaatctggt ttgtagataa
    26461 agtagcagga cgctttggta agaaagaaga aagtttagac aatcttaaat tacctaagtt
    26521 cctctcaatc ttccacgata cagttgttgc atctgctacc ttgatgctcg tattcttcgg
    26581 agccattctt ttaatcttgg gtccagacat tatgtctaat aaagaagtca tcacttcagg
    26641 aactctattc aatcctgcta aacaagattt ctttatgtac attatccaaa cagcctttac
    26701 cttctcagtt tacttgttcg ttttgatgca aggtgtccga atgttcgtat ctgagttgac
    26761 aaacgccttc caaggtattt caaacaaatt gttgccaggt tcattcccag cggttgacgt
    26821 tgcagcttct tatggatttg gttctccaaa tgctgtcctg tcaggattta tctttggttt
    26881 gattggtcaa ttgattacaa ttgttttgct catcgtcttt aaaaatccga ttcttattat
    26941 tataggattt gtaccagtgt tctttgacaa tgcagccatt gcggtctacg ctgataaacg
    27001 cggcggatgg aaagcggctg ttatcctttc ctttatatca ggtgtccttc aagttgctct
    27061 aggagctctt tgtgtggccc ttctcgattt ggcatcttat ggtggctacc atggaaatat
    27121 cgactttgaa ttcccatggc ttggatttgg atatatcttc aaataccttg gtattgttgg
    27181 ttatgtactt gtgtgtctct tcttgcttgt tattcctcaa cttcaatttg ccaaagcaaa
    27241 agataaagag aaatattaca acggtgaagt tcaagaagaa gcttagtatc tagaaaagga
    27301 gaaataaaat ggttaaagta ttagcagcgt gcggaaatgg aatgggttca tcaatggtta
    27361 tcaagatgaa ggttgaaaat gctctccgta agcttaatca aacagatttt acagtcaatt
    27421 catgcagtgt cggtgaagct aaaggtttag cagtaggata tgacatcgta atcgcttctc
    27481 ttcatttgat tcaagaattg gaagggcgaa ctaatgggaa gttaattggg cttgataact
    27541 tgatggatga taaagaaatc accgaaaaac tcagtcaagc actacagtaa aaggttggag
    27601 ggggctggac agaaactgag agttatcgtt tctgtccttc tccctcttta aataaaggag
    27661 gcagatatga atttaaaaca agctttaatt gacaacgact cgatccgact aggtttagag
    27721 gctaacgatt ggaaagaagc agtcaaggta gcagtagatc ccttgattga aagtggggca
    27781 attttgccag agtattacga tgctatcatt gaatcgactg aagagtatgg gccttactat
    27841 atcttgatgc caggtatggc tatgccccac gctagacctg aagctggtgt gcaaagtgat
    27901 gccttttcat taattacctt acaaaatcct gttgtatttt cagatgggaa agaggtatct
    27961 gttttgttgg cactagcagc aacaagttca aaaattcaca caagtgtagc cattccacaa
    28021 attattgccc tgtttgaatt agaagattct attgcacgtt tacaggcttg ccagactaaa
    28081 gaagatgtct tggctatgat tgaagaatct aaggatagcc cttatctcga aggattggat
    28141 ttggaaagtt agaaagagga ataaagaaat gacaaaaaga atacctaatt tacaagttgc
    28201 attagaccat tcagacttgc aaggagcgat taaagcagct gtttctgttg gtcaggaagt
    28261 agatattatc gaagctggaa ctgtttgctt gcttcaagtt ggaagtgaac tggctgaagt
    28321 cttgcgtagc cttttcccag ataagattat tgtggcagac acaaaatgtg ctgatgctgg
    28381 tggaacagtt gctaaaaata atgcggttcg tggagcagac tggatgactt gtatctgttg
    28441 tgcaaccatc cctactatgg aagcagctct aaaggctatc aagactgaac gaggagaacg
    28501 aggcgaaatc cagatcgagc tttatggcga ttggactttt gaacaagctc agctttggct
    28561 agatgcaggt atctcacaag ctatttatca ccaatctcgt gatgctcttc ttgctggtga
    28621 aacttggggt gaaaaagacc ttaataaggt taaaaaactc attgacatgg gcttccgtgt
    28681 atctgtaaca ggtggtctag atgtagatac tctcaaactc tttgaaggtg ttgatgtctt
    28741 tacctttatc gcaggtcgtg gaattacaga ggctgtggat ccagcaggag cagcgcgtgc
    28801 cttcaaggat gaaatcaaac gaatttgggg gtaaatcatg gtacgtccaa ttggaattta
    28861 tgaaaaggca accccaacac actttacttg gctagaacgt ttaaattttg ccaaggagtt
    28921 aggctttgat tttatcgaga tgtctattga cgaacgtgac gagcgtttag caagacttga
    28981 ctggagtaag gaagaacgct tggaagttgt caaagaaatc tatgaaactg gtgttcgtat
    29041 tccttctatc tgtttttcag gccatcgtcg ctacccattg ggatcaaaag attcagttct
    29101 agaggaaaaa tctctagaac tcatgaaaaa atgtatcgaa ttagctcaag acttgggagt
    29161 tcgtacgatt caattagctg gttacgatgt ttactatgag gaaaagtcac cccagacacg
    29221 ccaacgtttt atcaaaaatt tgagaaaatc ctgtgactgg gctgaagaag ctcaggtggt
    29281 acttgctatt gaaattatgg atgatccttt catcagtagc atcgaaaaat atttggctat
    29341 agaaaaagag attgactctc ccttcctctt tgtatatcca gatattggta atgtgtctgc
    29401 atggcataat gatatctata gtgagtttta tcttggtcat catgccatcg cagctctcca
    29461 tctcaaggat acttatgcag tgacagaaag ttcaaagggc cagttccgag atgtaccttt
    29521 cgggcaaggt tgtgtcaaat gggaagaagc tttcgatatt ttaaaggaaa ccaattataa
    29581 tggacctttc ctaatcgaaa tgtggtctga aaattgtgaa acagtagaag aaacacgcgc
    29641 agccattcaa gaggcgcaag cttttctcta tccactcatt aagaaagcag gtttgatgta
    29701 agatgaatca agtaatcaat gctatgcgta aacgagtctg tgatgccaat caatcattgc
    29761 caaaacatgg acttgtcaaa tttacctggg ggaatgtatc tgaagttaat cgcgaactcg
    29821 gtgtcattgt tatcaaacca tcaggcgtgg attatgacga attgacacct gaaaacatgg
    29881 tagtgactga tctagatggt aagatcctag aaggggattt aagaccatct tccgacctcc
    29941 caactcatgt gcaattatat aaggcttggt cagaaattgg tagtgtggtt cacacccatt
    30001 cgacagaagc tgttggttgg gctcaggcag gtcgtgatat tcctttctac ggaacaaccc
    30061 atgcagatta tttctacggt tcaatccctt gcgcccgtag tttgaccaag gacgaagtag
    30121 aagtggccta tgaaaaagat actggcctgg ttatcgtaga agagtttgaa catcgcggac
    30181 ttaacccggt tgaagtacca ggaattgttg tacgcaatca cggtccattc acctggggca
    30241 aaaatccaga gaatgctgtt tatcactctg tcgtactaga ggaagtatca aagatgaatc
    30301 gctttacaga acaaatcaat ccaagagttg gacctgctcc ccagtacata ctagaaaaac
    30361 actaccaacg taaacatgga ccaaatgctt attatggtca aaagtaagaa cgatgaagga
    30421 ggagaaaaag ataaatttag ctcctctttt tacatttgat ttttattgag agtaaagttg
    30481 gaattgaagt aattttaaaa gattttttag aaatagcgct tgatatatat atggtaaaat
    30541 aaaaagaatt gctgtgatat caatagattt gggggatttt ttaatatggt actggataag
    30601 gcaagttgtg atttgcttca atatttgatg gatcaagaaa cgtccaaaac gattatggcg
    30661 atttcgaaag atttgaaaga gtcaagaagg aaaatttatt atcacattga caaaatcaat
    30721 gctgctctgg gtgacgaggc gcttcacatc attagtattc cacgaattgg tattcactta
    30781 acggaagagc agagagatgc ttgttgtaaa ctattatcgg aagtagattc gtacgattat
    30841 atcatgagtg cgcatgaacg tatgatgata atgttactat ggataggtat ttctaaagaa
    30901 cgtattacga ttgaaaaatt gatagagtta acagaggtat ctaggaatac tgttctcaat
    30961 gatttgaata gtattcgtta tcaactaact ttggaacaat atcaggtgat cttgcaagtg
    31021 agcaagtcac agggatacca ccttcatgcc caccctctta ataaaattca gtatcttcaa
    31081 tcgcttctat atcatatttt tatggaagaa aatgccactt ttgtatctat tttagaagat
    31141 aagatgaaag agaggttaga tgatgagtgt ttgctttctg ttgaaatgaa ccaatttttt
    31201 aaggaacagg ttcctttagt tgaacaagat ttagggaaga aaataaacca tcatgaaata
    31261 acttttatgt tgcaggttct accttatttg ctgttaagct gtcataatgt tgaacagtat
    31321 caagaaagac atcaggatat agagaaagaa ttttctttga taagaaaaag aatagagtat
    31381 caggtgtcta agaaattagg agaacggttg tttcaaaagt ttgaaatttc tttgtcagga
    31441 cttgaagttt ctcttgtagc tgttctcctc ctctcctatc gtaaagattt ggatattcat
    31501 gcagaaagtg atgattttcg gcaattaaaa cttgctttag aagaatttat ctggtatttt
    31561 gaatcacaaa tccgaatgga gattgagaac aaggatgatt tgttacgaaa tttgatgatc
    31621 cactgtaaag ccttgttatt tagaaagact tacggtattt tttctaaaaa tcctctaaca
    31681 aaacaaattc gatccaagta tggagaatta tttttagtca ctagaaaatc tgcggaaatt
    31741 ttagaaggag catggtttat tcggctaaca gacgatgata ttgcctattt gacgattcat
    31801 attggaggat ttttaaaata tacaccatcg tctcaaaaaa atatgaaaaa agtttatctc
    31861 gtttgtgatg aaggtgttgc ggtttcgaga cttttgctga aacaatgcaa actttatttt
    31921 ccaaatgagc aaattgacac tgtatttaca acagaacaat ttaagagtgt ggaagatatt
    31981 gcacaagttg atgtagtgat tactactaat gatgatttgg atagcagatt tccgatttta
    32041 agggttaatc ctatccttga agcagaagat attttgaaaa tgctagacta tcttaaacac
    32101 aatatatttc gtaataagag caaaagtttc agtgaaaatc tttctagtct tatttcgtct
    32161 tatattgtag acagcaagtt ggctagtaag ttccaagaag aggttcaaac acttataaat
    32221 caagaaatag tagttcaagc ttttttggaa gatatttgaa ggacagtcca atgatgaaca
    32281 caaacctgtg tttttcttgg tcttttttag tgttttgaag ggtggtatac taatctcaaa
    32341 gataacaatt atatccaaag gaggcaacat atgccaaacg tcaaagaaat tacaagagag
    32401 tcatggattt tagccacttt cccagagtgg ggaacatggt tgaacgaaga aatcgaagaa
    32461 gaagtcgtac ctgaaggcaa ctttgccatg tggtggctag gcaactgtgg tacttggatt
    32521 aagacaccag ctggtgctaa cgttgtcatg gacctttggt caaaccgtgg aaaatcaacc
    32581 aaaaaagtga aagatatggt tcgtgggcac caaatggcaa atatggcagg tgttcgtaag
    32641 ttgcaaccaa acttgcgtgt tcagccaatg gttatcgatc catttgctat caacgaacta
    32701 gactattact tagtttcaca cttccacagt gatcatatcg acccatacac agctgcagca
    32761 attctcaaca atcctaagtt agagcatgtt aagtttatcg gtccttacca ctgtggacga
    32821 atctgggaag gatggggtgt tccaaaagaa cgtatcatcg ttgttaaacc aggtgacact
    32881 atcgaattaa aagatatgaa gattcatgca gtagaatcat ttgaccgtac ttgcttggta
    32941 actctcccag tgaacggtgc tgatgagaca ggcggtgaac ttgctggctt ggctgttaca
    33001 gatgaagaaa tggctcaaaa ggctgttaac tatatctttg aaacaccagg tggaaccatc
    33061 tatcatggtg cagattctca cttctcaaac tattttgcaa aacatggtaa agactttaaa
    33121 attgatgttg ctttgaataa ctatggtgaa aatccggtag gtatccaaga caaaatgaca
    33181 tctatcgacc ttcttcgtat ggcagaaaat ctgcgtacca aagtcattat cccagttcac
    33241 tatgatatct ggtctaactt catggcttct actaatgaga ttctagaact ttggaaaatg
    33301 cgaaaagatc gcttgcaata cgatttccat ccatttatct gggaagttgg cggtaagtac
    33361 acttatcctc aagatcaaca cttagtagaa taccatcatc cacgtggttt tgatgattgt
    33421 tttgaacaag actctaacat tcaatttaaa gctttgctat aatataaaaa tattctttgg
    33481 aggttatccg tatgttgcat gatacggata attttcatat aatagtaaaa tagaatgtgt
    33541 gattcaataa tcacctcaaa tagaaaggaa attctatgtc aaatctatct gttaatgcaa
    33601 ttcgttttct aggtattgac gccattaata aagccaactc aggtcatcca ggtgtggtta
    33661 tgggagcggc tccgatggct tacagcctct ttacaaaaca acttcatatc aatccagctc
    33721 aaccaaactg gattaaccgc gaccgcttta ttctttcagc aggtcatggt tcaatgctcc
    33781 tttatgctct tcttcacctt tctggttttg aagatgtcag catggatgag attaagagct
    33841 tccgtcaatg gggttcaaaa acaccaggtc acccagaatt tggtcatacg gcagggattg
    33901 atgctacgac aggtcctcta gggcaaggga tttcaactgc tactggtttt gcccaagcag
    33961 aacgtttctt ggcatccaaa tataaccgtg aaggctacaa tatctttgac cactatactt
    34021 acgttatctg tggagacgga gacttgatgg aaggtgtctc aagcgaggca gcttcatatg
    34081 caggcttgca aaaacttgat aagttggttg ttctttatga ttcaaatgat atcaacttgg
    34141 atggtgagac aaaggattcc tttacagaaa gtgttcgtga ccgttacaat gcctacggtt
    34201 ggcatactgc cttggttgaa aatggaacag acttggaagc catccatgct gctatcgaaa
    34261 cagcaaaagc ttcaggcaag ccatctttga ttgaagtgaa gacggttatt ggatacggtt
    34321 ctccaaacaa acaaggaact aatgctgtac acggcgcccc tcttggagca gatgaaactg
    34381 catcaactcg ccaagccctc ggttgggact acgaaccatt tgaaattcca gaacaagtat
    34441 atgctgattt caaagaacat gttgcagacc gtggcgcatc agcttatcaa gcttggacta
    34501 aattagttgc agattataaa gaagctcatc cagaactggc tgcagaagta gaagccatca
    34561 tcgacggacg tgatccagtc gaagtgactc cagcagactt cccagcttta gaaaatggtt
    34621 tttctcaagc aactcgtaat tcaagtcaag atgccttgaa tgttgtggca gctaaattac
    34681 caaccttcct aggtggatca gctgaccttg ctcactcaaa catgacttat ataaagacgg
    34741 atggacttca agacgatgcc aatcgcttga atcgtaacat tcagtttggt gttcgtgaat
    34801 ttgcaatggg aacaatcttg aacgggatgg cccttcatgg tggacttcgt gtatacggtg
    34861 gaactttctt cgtcttctct gactatgtga aggcagctgt ccgcttgtca gccttacaag
    34921 gacttcctgt gacttatgtc tttacccatg attcaatcgc agttggggaa gatggtccga
    34981 ctcacgaacc agttgagcat ttagcaggtc ttcgtgctat gccaaatcta aatgttttcc
    35041 gtccagcaga tgcgcgtgaa actcaagcag cttggtacct tgcagtgaca agtgagaaaa
    35101 caccaactgc ccttgttttg acacgtcaaa acttgactgt tgaagatgga acagacttcg
    35161 acaaggttgc taaaggtgct tatgttgtat atgaaaatgc agccgacttt gataccatct
    35221 tgattgcgac aggttcagag gttaatcttg ctgtctcagc tgctaaagaa ttggctagtc
    35281 aaggcgaaaa aatccgcgta gtcagcatgc catctacaga tgtctttgat aaacaagatg
    35341 cagcttacaa ggaagagatt cttccaaatg cagtccgccg tcgtgttgca gtcgaaatgg
    35401 gtgcaagtca aaactggtac aaatatgttg gtctcgatgg tgccgttcta ggtattgata
    35461 ccttcggagc ctctgcccca gcaccaaaag tattggcaga atatggcttt actgtagaaa
    35521 atcttgtaaa aattgttcga aacttgaaat aatcctaaaa atcagggcgt aagctctggt
    35581 ttttcttacc agaaaagtaa ggtacaatct tgtaaaagta gctgaaattt gatatagtag
    35641 tcctatgtaa aagacaaagg agaaaacaat gaatccaaat attacttttt taatcatgct
    35701 tgtaggtatg atggccttga tgttctttat gcaacgttct caaaagaaac aagctcaaaa
    35761 gcgtatggaa agcttaaata aactacaaaa aggctatgaa gtgattacaa tcggtggact
    35821 ttatggaaca gtcgatgaag tagatacgga gaagggaaca atagttcttg acgtagatgg
    35881 agtttacttg acttttgaac tagctgctat caagacagta ttaccgctga aagaaacagc
    35941 ttcactagaa ggcgcaattg aaaaataaga cgggatcacg aactcccgtt tttctataaa
    36001 agaaaggaaa tgggatgaaa aaattagtct ttgtctgtct gggaaatatt tgccgtagcc
    36061 ctatggccga gtttgttatg aaatcaatga cagataacta cgaaatccaa agtcgagcaa
    36121 cttcctcttg ggaacatggc aatccgattc ataaggggac tcagggaatt tttcaagagt
    36181 atgagattcc ttatgacaag aacaagacat cgcttcagat tagtaaggaa gattttgaag
    36241 cctttgatta tattatcgga atggacgctt caaatgtttc cgacttacgt cagatgtgtc
    36301 cagtagactg tcaagataag atttactcat tttcatctga aagtgttcca gacccttggt
    36361 atacaggaga ttttgaagaa acctatcgac gtgttcaaga gggttgtcaa gcttggttag
    36421 aacgtttaga aaaggagagt taaggtggaa aatcttacga atttttacga aaagtatcgt
    36481 gtttatctga ctcgtccacg tttagagatt ttggcagtag ttaccattgt tttctgtgct
    36541 gtactcgtct tttttctaaa tattccagga aaaggtgtct taaaactcga taatggaacg
    36601 attgtttatg atggcagtct tgtccgcggt aaaatgaatg gccaaggtac cattaccttc
    36661 caaaatggag accaatatac aggtggcttc aacaatggag ccttcaacgg aaaaggtacc
    36721 tttcaatcta aagaaggctg gacctacgaa ggtgattttg taaatggtca ggctgaagga
    36781 aaagggaaac taacaacaga acaagaagtc gtttatgaag gaacttttaa acaaggcgtt
    36841 tttcaacaaa aataaagcct ccttatcaaa ggaggtatta ttagaatcgc aaggtaagcg
    36901 cttacttgca aatccctttc tttccaaatc cctcttccaa ccaagtttgt gaaataaaaa
    36961 atatttgaaa taaatttcac aaacttcaaa gataaaacct gataagaaaa gaaaatgaga
    37021 aaagtttcac aagagtttaa aaattctttg tgaaatgttt atgaaactgt ttacaaagtt
    37081 gaaataatac gttataataa acttgtgaaa aaattaacaa aggatatcgt tccttgaaag
    37141 ctatggagga aaatatggct gataaaaaaa ctgtgacacc agaggaaaag aaactcgttg
    37201 ctgaaaaaca cgtagatgag ttggttcaaa aagctctagt tgcccttgaa gaaatgcgta
    37261 aattggatca agagcaagtt gactacatcg ttgccaaagc atcagtagca gctttggatg
    37321 cccacggaga attggcttta catgcctttg aagaaacagg acgtggtgta tttgaagaca
    37381 aagcaactaa gaacttgttt gcctgtgaac acgtagtaaa caacatgcgc cacactaaga
    37441 cagttggcgt tatcgaagaa gacgatgtaa caggattgac tcttattgct gaaccagttg
    37501 gtgttgtttg tggtattact ccaacaacaa acccaacatc aacagcaatc ttcaaatcat
    37561 tgatttcatt gaagacacgt aacccaatcg tctttgcctt ccatccatca gcacaagaat
    37621 catctgctca tgcagctcgt atcgtccgcg atgcagctat cgcagctggt gctcctgaaa
    37681 actgtgtgca atggattact caaccatcta tggaagcaac aagtgccctt atgaaccacg
    37741 aaggtgttgc gacaatcctt gcaacaggtg gtaatgccat ggttaaggcg gcttattcat
    37801 gtggtaaacc agctcttggg gtaggtgccg gaaacgttcc agcttatgtt gaaaaatcag
    37861 caaacattcg tcaagcagca cacgatatcg tcatgtctaa atcatttgat aacggtatgg
    37921 tctgtgcatc tgaacaagca gttatcattg ataaagaaat ttacgatgaa tttgtagcag
    37981 agttcaaatc ttaccacact tactttgtaa acaaaaaaga aaaagctctt cttgaagagt
    38041 tctgcttcgg cgtcaaagca aacagcaaaa actgtgctgg tgcaaaattg aacgctgaca
    38101 tcgttggtaa accagcaact tggattgcag aacaagcagg atttacagtt ccagaaggaa
    38161 caaacattct tgctgcagaa tgtaaagaag ttggcgaaaa tgagccattg actcgtgaaa
    38221 aattgtcacc agttattgca gttttgaaat ctgaaagccg tgaagatggt attactaagg
    38281 ctcgtcaaat ggttgaattt aacggtcttg gacactcagc agctatccac acagctgacg
    38341 aagaattgac taaagaattt ggtaaagctg ttaaagctat tcgtgttatc tgtaactcac
    38401 cttctacttt tggtggtatc ggggacgttt acaatgcctt cttgccatca ttgacacttg
    38461 gatgtggttc ttacggacgc aactcagttg gggataacgt tagtgccatt aacctcttga
    38521 atatcaaaaa agtcggaaga cggagaaata acatgcaatg gatgaaactt ccttcaaaaa
    38581 catactttga acgtgattca attcaatacc ttcaaaaatg tcgtgacgtt gaacgtgtca
    38641 tgatcgttac tgaccatgcc atggtagagc ttggtttcct tgatcgtatc atcgaacaac
    38701 tggaccttcg tcgcaataag gttgtttacc aaatctttgc ggatgtagaa ccggatccag
    38761 atatcacaac tgtaaaccgt ggtactgaga ttatgcgtgc cttcaaacca gataccatca
    38821 tcgcactcgg tggtgggtct ccaatggatg ctgccaaagt aatgtggctc ttctacgagc
    38881 aaccagaagt ggacttccgt gaccttgtcc aaaaattcat ggatatccgt aaacgtgcct
    38941 tcaagttccc attgcttggt aagaagacta aattcatcgc gattccaact acatctggta
    39001 caggatctga agtaacacca tttgccgtta tctctgataa agcaaacaac cgtaaatacc
    39061 caatcgctga ctactcattg acaccaactg tggcaatcgt agatcctgct ttggtattga
    39121 cagttccagg atttgttgct gctgatactg gtatggacgt attgactcac gcgacagaag
    39181 catacgtatc acaaatggct agtgactaca ctgatggttt agcacttcaa gccattaaat
    39241 tggtctttga aaatctcgaa agctcagtta agaatgcaga cttccactca cgtgagaaaa
    39301 tgcataacgc ttcaacaatc gctggtatgg cctttgccaa tgccttccta ggtatttctc
    39361 actcaatggc ccataagatt ggtgcgcaat tccacacaat ccacggtcgt acaaatgcca
    39421 tcttgcttcc atacgttatc cgttacaacg gtacacgtcc agctaagaca gcaacatggc
    39481 ctaagtacaa ctactaccgt gcagatgaaa aataccaaga tatcgcacgc atgcttggac
    39541 ttccagcttc tactccagaa gaaggggttg aatcttacgc aaaagctgtc tacgaactcg
    39601 gtgaacgtat tgggatccaa atgaatttta gagaccaagg aattgacgaa aaagaatgga
    39661 aagaacattc tcgtgaatta tccttcctgg cttatgaaga ccaatgttca ccagctaacc
    39721 cacgtcttcc aatggtagac catatgcaag aaatcatcga agatgcatac tatggctaca
    39781 aagaaagacc aggacgccgt aaataattgt ttatcagtct agaagcaaga caaaaactca
    39841 atttgaggga aagatccagt aatttttcta tgataaaagg catcctatca aggtttttga
    39901 atacctgata ggatgccttt ttatgatgtt gaggcctttt tgcccttttt gaaaaactag
    39961 aatagaaaca aaatatatag cagattgaaa ctagaatagt acacatctgc ttctaaaaca
    40021 ttgttagaat tcgatttgac tgtcctgatc gatttgttc
//
LOCUS       DAVKXA010000016        36927 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKXA010000016 DAVKXA010000000
VERSION     DAVKXA010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.016"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            72..350
                     /locus_tag="VW883_000874"
     CDS             72..350
                     /locus_tag="VW883_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274041.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            352..2415
                     /locus_tag="VW883_000875"
     CDS             352..2415
                     /locus_tag="VW883_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0274042.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(2493..3749)
                     /locus_tag="VW883_000876"
     CDS             complement(2493..3749)
                     /locus_tag="VW883_000876"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0274043.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            3891..6356
                     /locus_tag="VW883_000877"
     CDS             3891..6356
                     /locus_tag="VW883_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0274044.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMTKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVDDYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            6421..7332
                     /locus_tag="VW883_000878"
     CDS             6421..7332
                     /locus_tag="VW883_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0274045.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            7562..8260
                     /gene="dapD"
                     /locus_tag="VW883_000879"
     CDS             7562..8260
                     /gene="dapD"
                     /locus_tag="VW883_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0274046.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            8328..9458
                     /locus_tag="VW883_000880"
     CDS             8328..9458
                     /locus_tag="VW883_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0274047.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            9470..10012
                     /locus_tag="VW883_000881"
     CDS             9470..10012
                     /locus_tag="VW883_000881"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0274048.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQFIDQTLTERLLHHPFYQEAKVI
                     ATYLSFPHEFQTQELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPEFDKDIPVQEVLIDEGNL"
     gene            9996..10673
                     /locus_tag="VW883_000882"
     CDS             9996..10673
                     /locus_tag="VW883_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0274049.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            10687..10764
                     /locus_tag="VW883_000883"
                     /pseudo
     CDS             10687..10764
                     /locus_tag="VW883_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10974..11909)
                     /locus_tag="VW883_000884"
     CDS             complement(10974..11909)
                     /locus_tag="VW883_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274050.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSSGASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGGQDYSGSGDSSTNGGSSEQYSSRNSNSGANNGYYKKYKNIDASG
                     HVRDTYHNESNGDVFDENGNYLGNTGGGIAEPPQR"
     gene            complement(12327..13226)
                     /gene="galU"
                     /locus_tag="VW883_000885"
     CDS             complement(12327..13226)
                     /gene="galU"
                     /locus_tag="VW883_000885"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0274051.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(13248..14264)
                     /locus_tag="VW883_000886"
     CDS             complement(13248..14264)
                     /locus_tag="VW883_000886"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0274052.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVGAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            14476..14856
                     /locus_tag="VW883_000887"
     CDS             14476..14856
                     /locus_tag="VW883_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0274053.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(15030..15455)
                     /locus_tag="VW883_000888"
     CDS             complement(15030..15455)
                     /locus_tag="VW883_000888"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274054.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(15531..16181)
                     /gene="phoU"
                     /locus_tag="VW883_000889"
     CDS             complement(15531..16181)
                     /gene="phoU"
                     /locus_tag="VW883_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0274055.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(16196..16948)
                     /gene="pstB"
                     /locus_tag="VW883_000890"
     CDS             complement(16196..16948)
                     /gene="pstB"
                     /locus_tag="VW883_000890"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0274056.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(16950..17765)
                     /gene="pstA"
                     /locus_tag="VW883_000891"
     CDS             complement(16950..17765)
                     /gene="pstA"
                     /locus_tag="VW883_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0274057.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(17758..18621)
                     /gene="pstC"
                     /locus_tag="VW883_000892"
     CDS             complement(17758..18621)
                     /gene="pstC"
                     /locus_tag="VW883_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0274058.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(18739..19614)
                     /locus_tag="VW883_000893"
     CDS             complement(18739..19614)
                     /locus_tag="VW883_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV0274059.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIESKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(19781..21112)
                     /locus_tag="VW883_000894"
     CDS             complement(19781..21112)
                     /locus_tag="VW883_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0274060.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(21113..21820)
                     /locus_tag="VW883_000895"
     CDS             complement(21113..21820)
                     /locus_tag="VW883_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274061.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(21904..22206)
                     /locus_tag="VW883_000896"
     CDS             complement(21904..22206)
                     /locus_tag="VW883_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0274062.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYETVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(22193..22414)
                     /locus_tag="VW883_000897"
     CDS             complement(22193..22414)
                     /locus_tag="VW883_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0274063.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYVRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            22376..22934
                     /locus_tag="VW883_000898"
                     /pseudo
     CDS             22376..22934
                     /locus_tag="VW883_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23249..24940)
                     /locus_tag="VW883_000899"
     CDS             complement(23249..24940)
                     /locus_tag="VW883_000899"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0274064.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NEDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            25076..25522
                     /gene="argR"
                     /locus_tag="VW883_000900"
     CDS             25076..25522
                     /gene="argR"
                     /locus_tag="VW883_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0274065.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            25573..28107
                     /gene="mutS"
                     /locus_tag="VW883_000901"
     CDS             25573..28107
                     /gene="mutS"
                     /locus_tag="VW883_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0274066.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            28254..29948
                     /gene="patA"
                     /locus_tag="VW883_000902"
     CDS             28254..29948
                     /gene="patA"
                     /locus_tag="VW883_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0274067.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(30278..30541)
                     /locus_tag="VW883_000903"
                     /pseudo
     CDS             complement(30278..30541)
                     /locus_tag="VW883_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            30735..32501
                     /gene="patB"
                     /locus_tag="VW883_000904"
     CDS             30735..32501
                     /gene="patB"
                     /locus_tag="VW883_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0274068.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSAGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            32640..33329
                     /locus_tag="VW883_000905"
     CDS             32640..33329
                     /locus_tag="VW883_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0274069.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            33333..33512
                     /locus_tag="VW883_000906"
     CDS             33333..33512
                     /locus_tag="VW883_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274070.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            33499..34848
                     /locus_tag="VW883_000907"
     CDS             33499..34848
                     /locus_tag="VW883_000907"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0274071.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            34972..36432
                     /locus_tag="VW883_000908"
     CDS             34972..36432
                     /locus_tag="VW883_000908"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0274072.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            36446..36880
                     /locus_tag="VW883_000909"
     CDS             36446..36880
                     /locus_tag="VW883_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0274073.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        10802 a         7096 c         7987 g        11042 t
ORIGIN      
        1 tctccaattt atagaatgaa attgctttta tatctaaatt gctatataat aatgataagg
       61 aggaaataag tatgttaaaa gaagtattaa ccgttgcaaa agttgcgaaa aaatcttcat
      121 tatttttggg tggtgtcgca tttggtaccc ttggtttgaa aatcttagca agtaaggaag
      181 ctaaaaaagg ttattctaaa gctttggcta aggcttacaa gttgaaagac gagctagatg
      241 catctgtttc tgttgtgaag caacatggag acgatgtctt gcaagatgcc aaatatttgt
      301 acgagcaaga gaaaaaagaa gagcaattag atagccttat aggtgaataa tatgtctttt
      361 aaagtgctac atagaggata ccaacatatc cgactatcat cttctttttc acttaccttg
      421 gatattcaag actatcttcg ttccttggcg agagatgaaa aggggattga gtctatccag
      481 ttttacatgg atcaacagca ctttactcta cgcataaaag aaggcttttc tgtattagat
      541 aatgcagaag cctttttaaa aagaattgat aaagggaaag tttctgagtt gatgactctt
      601 cccattcgta gagaagagag tgcttattct attgtttcag gtgcagcggt taagcgtgta
      661 ctttttcgta gttttgtgcc gtatcctatt cgctatatat ggacttgtta tcaggctttg
      721 ggttatatta gagaagccta tcaaacacta gcgcgtaagg aactaacgat ggaagtcttg
      781 gactgttcgg ctattttatt gtctttgttt atgaaccaat ccaagacagc tagcaatatc
      841 atgtttatgc ttgatttggg gaatcattta gatcagtggt ccttgaaaaa aactgcaaca
      901 gatttagaac agagtcttct tgcaaaagag agcgatgtat tcctagtaca gggcgatacg
      961 gttgttagta tcaagagttc cgatgttcaa ataggagatg tcttgatctt atctcaagga
     1021 aatgaaattc tgtttgatgg acaagtagtt tcaggtttag gtatggtcaa cgaaagttcc
     1081 ttgacaggag agagttttcc agttgaaaaa agagagtctg atttggtttg tgcaaataca
     1141 gtattagaaa ctggagagtt acgcattcgt gtaacagata atcagatgaa cagccgtatt
     1201 ttacagctga ttgagttgat gaagaaatct gaagaaaaca agaaaacgaa acaacgctat
     1261 ttcatcaaga tggcggataa agtcgtcaaa tataatttct tgggggctgg gctgacttac
     1321 ctattgacag gttctttttc taaggctatt tctttcctat tggtcgattt ctcctgcgct
     1381 ttgaaaatct ctactcctgt agcttatttg acagttatca aggaggggtt gaaccgtgaa
     1441 atggtgatta aggatggaga tgttctggag aaatatctgg aagttgatac tttcttgttt
     1501 gataagacag gaacaatcac aactagttat cctatagttg aaaaggtgtt accttttgga
     1561 gactatagtg aggaagatat tctcagaatc agtgcctgtc ttgaggaaca catttatcat
     1621 cctattgcta atgccatcgt caagcaagct gagatagagg gaattgaaca tgaggaaatg
     1681 catgggaaac tccaatatat cgcaagcaag gggatcaaat ctcatataga tggccaacca
     1741 gttcttattg ggaattatgt cttgatgcag gatgagcaga ttcatatcag ttcagaacaa
     1801 aatgctttaa ttgaagagta caagagtcac tacaatctct tattcttggc ttatcaaaat
     1861 gaattgattg gaatgttctg cattcatact cctttgagaa aagaagcaaa aacagccttg
     1921 gataaactta aggcacaggg gaaaaaattg attctggcaa caggagacac cttgattagg
     1981 acagaggaat tagtcaaaga tttgcccttt gatcaggtct atacagactt gaaacctgat
     2041 gggaaatttg agttagtaga gaaactgcag aaagcaggtc acactatttt gatggttgga
     2101 gatggattga atgactcagc ggctttaact ctatcagata tcggtgtggt gatgaatgag
     2161 agtgcagata tttctaagca gatgagtgat atcttattgt tagataatcg tttggatttc
     2221 ttccaagagt tggattcgtt atcatcatct ttgcaaacac tcatcaagaa aaatattcaa
     2281 gataccgttg tcgtaaatag tagtttgatt ggctttggct tatttaattg gttcagtcct
     2341 tcaaatctct ctatcttaca taatctaaca accttgcgca ttgtcttgcg tagcctgtct
     2401 attaaaaata gatagatgag agttattaac agcaaaaagg agttaccttt ctcgaggtta
     2461 actcctttgt ttatagataa atgttgaata gtttagtaag tcaatacaaa gtattttttc
     2521 ttcccacgac ggataacagt cagttcattt tctaacttat cagcgtcact caagacatag
     2581 tcaaggtctt ggatgcggtc gccgtttacg tagatggctc cgttttggac gtcttcacgg
     2641 gcttggcgtt ttgagttaac tataccagat gagacgagca gttccacgat attgttatgt
     2701 tcgtctgcct gtacttggta gtttggcaca ccacgaagtc cttgtttgag ctctttgaca
     2761 gaaaggtttt tgatgtttcc tgcaaagagt tgctcagtga tgttaagtgc ttctttgtag
     2821 gcttcttctc cgtgaacaag tgtaacaact tcacgagcca agactttttg agccaagcgt
     2881 tcgtgtggcg ctgcttcaaa ttgtttacga atatcttcaa tctcatcaag tgacaagaaa
     2941 gtaaagattt tcaagaagcg aacagcgtca gcgtccatca cgttcatcca gaattggtac
     3001 atttcgtatg gagaagtctt ttcgggattg agccagacgg catttccttc tgatttacca
     3061 aattttttac cagttgcatc tgtgattagt ggaacagtga taacgtgacc agtcttgtcc
     3121 gccttacgac gaagcaattc ggtaccagct gtcatatttc cccactggtc agaaccaccg
     3181 atttgaagag tgacattatg gtcttggtta aggacgaaga agtcgtaccc ttgcatgatt
     3241 tggtaagcga actcagtgta agaaattcct gtttcgatcc gttttttaac agattcctta
     3301 ctcatcatgt agttgaccgt gaagtatttt ccaatatcac ggaggaagtc aatgaagctg
     3361 atgctgccaa accagtcgta gttgttgacc atgacagcct tgttttcgcc attttcaaag
     3421 tcaagaaaac gagaaagttg tccttggata gacttgaccc agccatctac tgtgtctttt
     3481 gtttggagac tacgttcagc atctttgaag gacggatctc cgatgagacc tgtagcaccg
     3541 ccaacgagcg cataaggttt gtgacctgct agttgcaagc gacgacttgt caagattgcg
     3601 acaaggtggc ctaggtgaag gctgtcagca gttggatcgt agccagtata ataagaaact
     3661 tgaccttctt ctagggcttt acgcaaagct tcttcatcag tcgtttgaaa tatcaaacca
     3721 cgctctttta gctcatcaaa aatgtgcatg tgtcttttct cctttttaaa attattgttt
     3781 ctacctattg tatcacaaac ttgggcaata gcctagcaga atagggaaga aagtggctat
     3841 tttattgaaa atttcccttt tgtggtataa tagatagagt gaggaaatcc atgcaaaatc
     3901 aattaaatga attaaaacga aaaatgctgg aatttttcca gcaaaaacaa aaaaataaaa
     3961 aatcagctag acctggcaag aaaggttcaa gtaccaaaaa atctaaaacc ttagataagt
     4021 cagccatttt cccagctatt ttactgagta taaaagcctt atttaactta ctctttgtac
     4081 tcggttttct aggaggaatg ttgggagctg ggattgcttt ggggtacgga gtggccttat
     4141 ttgacaaggt tcgggtgcct cagacagaag aattggtgaa tcaggtcaag gacatctctt
     4201 ctatttcaga gattacctat tcggacggga cggtgattgc ttccatagag agtgatttgt
     4261 tgcgcacttc tatctcatct gagcaaattt cggaaaatct gaagaaggct atcattgcga
     4321 cagaagatga acactttaaa gaacataagg gtgtagtacc caaggcggtg attcgtgcga
     4381 ccttggggaa atttgtaggt ttgggttcct ctagtggggg ttcaaccttg acccagcaac
     4441 taattaaaca gcaggtggtt ggggatgcgc cgaccttggc tcgtaaggcg gcagagattg
     4501 tggatgctct tgccttggaa cgcgccatga ctaaagatga gattttaacg acctatctca
     4561 atgtggctcc ctttggccga aataataagg gacagaatat tgcaggggct cggcaagcag
     4621 ctgagggaat tttcggtgta gatgccagtc agttgactgt tcctcaagca gcatttttag
     4681 caggacttcc acagagtccc attacttact ctccttatga aaatactggg gagttgaaga
     4741 gtgatgaaga cctagaaatt ggcttaagac gggctaaggc agttctttac agtatgtatc
     4801 gtacaggtgc attaagcaaa gacgagtatt ctcagtacaa ggattatgac cttaaacagg
     4861 actttttacc atcgggcacg gttacaggaa tttcacgaga ctatttatac tttacaactt
     4921 tggcagaagc tcaagaacgt atgtatgact atctagctca gagagacaat gtctccgcta
     4981 aggagttgaa aaatgaggca actcagaagt tttatcgaga tttggcagcc aaggaaattg
     5041 aaaatggtgg ttataagatt actactacca tagatcagaa aattcattct gccatgcaaa
     5101 gtgcggttga tgattatggc tatcttttag acgatggaac aggtcgtgta gaagtaggga
     5161 atgtcttgat ggacaaccaa acaggtgcta ttctaggctt tgtaggtggt cgtaattatc
     5221 aagaaaatca aaataatcat gcctttgata ccaaacgttc gccagcttct actaccaagc
     5281 ccttgctggc ctacggtatt gctattgacc agggcttgat gggaagtgaa acgattctat
     5341 ctaactatcc aacaaacttt gctaatggca atccgattat gtatgctaat agcaagggaa
     5401 caggaatgat gaccttggga gaagctctga actattcatg gaatatccct gcttactgga
     5461 cttatcgtat gctccgtgaa aagggtgttg atgtcaaggg ttatatggaa aagatgggtt
     5521 acgagattcc tgagtacggt attgagagct tgccaatggg tggtggtatt gaagtcacag
     5581 ttgcccagca taccaatggc tatcagacct tagctaataa tggagtttat catcagaagc
     5641 atgtgatttc aaagattgaa gcagcagatg gtagagtggt gtatgagtat caggataaac
     5701 cggttcaagt ctattcaaaa gctactgcga cgattatgca gggattgcta cgagaagttc
     5761 tatcctctcg tgtgacaaca accttcaagt ctaacctgac ttctttaaat cctactctgg
     5821 ctaatgcaga ttggattggg aagactggta caaccaacca agacgaaaat atgtggctca
     5881 tgctttcgac acctagatta accctaggtg gctggattgg gcatgatgat aatcattcat
     5941 tgtcacgtag agcaggttat tctaataact ctaattacat ggctcatctg gtaaatgcga
     6001 ttcagcaagc ttccccaagc atttggggga acgagcgctt tgctttagat cctagtgtag
     6061 tgaaatcgga agtcttgaaa tcaacaggtc aaaaaccagg gaaggtttct gttgaaggaa
     6121 aagaagtaga ggtcacaggt tcgactgtta ccagctattg ggctaataag tcaggagcgc
     6181 cagcgacaag ttatcgcttt gctattggcg gaagtgatgc ggattatcag aatgcttggt
     6241 ctagtattgt ggggagtcta ccaactccat ccagctccag cagttcaagt agtagttcta
     6301 gcgatagcag taactcaagt actacacgac cttcttcttc aagggcgaga cgataattct
     6361 ctaaatgaag tggccaatca atggattgcc acttttttcc tttcgtgtta caataagggt
     6421 atgaatcagt atcagaaaaa gattgttaac ggaaaaattt attcgctcct atccggctta
     6481 atatggggaa tctgtggaat tttaggagag tacttcttta ctcattatca ggtgtcttcg
     6541 ggctggatta cctctatgcg tttgacactg gcagggagtc ttgtactcat ttggtctgca
     6601 atacaattaa aatcgcaagt gctagatatt tggcgagaca agaaaaatta cctgcccttt
     6661 ttagcctatg ctattttggg gattttttca gttcagtatt ttttctatct ctgtgtagaa
     6721 tactcaaatg ctacgacagc aactatttta cagtttatta gccctgtctt tatcctcttt
     6781 tacaatcgct tggtttatca aaaacgagcg tcaaaaagcg ctgttttcta tgttttggtt
     6841 gccatgctgg gtgtttgctt gatggcgaca aagggagatc tctctcagtt atccatgacg
     6901 ccgctagctc ttataacagg tttgctgagt gccatgggtg ttatgtttaa tgttatcttg
     6961 ccccaacctt ttgctaagcg ttatggtttt gttcctacgg ttgggtgggg gatgattttg
     7021 gcaggtttgt ttagcaatgt cctctcgccg gtttatcagc tttcctttac tcttgatatt
     7081 tggagtatct tgatttgcct cattatcgct ttctttggaa cggcttttgc ttttttcatt
     7141 tccatgaagg ctgtgtcctt ggtttctcct ttggtggttg ccgttatcag tgccagtgaa
     7201 cctctctctt ctgctctctt gagtgttttg ttcttaggat tagtagtgga ttggtccctc
     7261 cttctagcta tagccttgat tattttaccc atgatatttt tgtctataga agaagcgaaa
     7321 gaaagtagat aaaaagtctt ttcttaattc taaaagtgtg ctatactaga atagtcaata
     7381 aaacacgggg agatagttgt gaagagtgtt tttaggttgt atcggtaggg gcttgctttt
     7441 accgacagca cgttttatct cacatcccta aaaaatcata cctaaaaaca gacaaaaagg
     7501 tttcaaattt gaggcctttt ttggtagaat aggtatcatt ataacgaacc aggaggcacc
     7561 tatgactgct acaaaaatga acgctcaaga aattatccaa tttatcgcca atgctgaaaa
     7621 gaaaaccagt gtcaaagtaa cctttgaggg gcaactcgca actgctgtgc ctagctctgt
     7681 tgtcaaacta ggaaatgtcc tattcggaga ctggaaggac gtggctccgc ttcttgaagg
     7741 tttggtagaa aatcaagatt atgttgtcga gcaagatgct cgtaattctg cagttccttt
     7801 gctagataag cgtgctatca acgctcgtat cgagccaggt gctattatcc gtgaccaggt
     7861 ggaaattggt gacaatgctg ttatcatgat gggagctgtt atcaatatcg gtgctgaaat
     7921 cggtgctgga accatgattg acatgggtgc catccttggt ggccgtgcca tcgttggaaa
     7981 aaatagccac gttggtgcag gtgcagtttt ggcaggtgtg attgagccag ctagtgctga
     8041 accagtccgt gtcggagaca atgttcttat cggtgctaat gcagtggtta tcgaaggagt
     8101 ccaaatcggt agtggttcag ttgtcgcagc aggagctatt gttacccaag atgtcccaga
     8161 aaacgtggta gtagcaggtg ttccagctcg tattatcaaa gaaattgatg cccaaactca
     8221 acaaaaaaca gcgctagagg atgcgcttcg taccttgtaa ttgtaaaagt aaaaaagagg
     8281 cggaaccctt tttccagcct ctttctgcta tatcggagga cagatagatg ttagatttga
     8341 ttcagactag acgagcttta caccagattc cagagattgg cttggaggag ttcaagactc
     8401 aggcttattt gctggatgtg attgagaaat tgactacggg caaggatttt gttcaaattc
     8461 gtacttggcg gacagggatt ttggtctacc tgcagggaag tcagccggag cgaaccattg
     8521 gttggcggac agatattgat ggcctgccta tcgtcgaaca aacaggtcta ccttttgctt
     8581 ctcaacacca aggtcgcatg catgcctgtg gccatgattt tcatatgacc attgccttag
     8641 gctgtcttga gcgcgccctt gaggagcaac ccaagaataa tctgctcttt ctatttcagc
     8701 ctgctgaaga aaatgaagct ggtggtatgc tcatgtatga ggatggtgct tttggagatt
     8761 ggttgccaaa ccaattctat ggtctccatg ttcgtccaga tttgaaagtc ggccagattg
     8821 cgactaatac tcatacactc tttgcaggaa cttgcgaggt gaagatccgt ttcaaaggca
     8881 aaggtggcca cgcagctttt cctcatgaag ccaatgacgc cttggtggcg gctagttact
     8941 ttgtgaccca agtgcagtca gttgttagcc gcaatgtcaa cccaatcgag ggagcagtgg
     9001 tgaccttcgg cgtttttcaa gctggaacca ccaacaatgt catcacagac acagcttttt
     9061 tacatggaac tattcgtgcc ttgacacagg acatgagtct cttggtgcaa aagagggtaa
     9121 aaacagttgc agaaggggtt gcagctgcct ttgatatgga agtcgaagtg gaactcaaac
     9181 aaggtggata cctacctgtt gagaacaatc cagccttggc gcgtgaactg atggacttct
     9241 ttgacgaaaa agacggaatc gagttgattg atatcgaacc tgctatgaca ggcgaggact
     9301 ttggttatct cctttcaaag gttgatggcg tgatgttttg gctaggtatc gatagtccct
     9361 acgctcttca tcaccctcaa atgagtccta aggaagaagt cttagctatt ggggtggctg
     9421 cggtgtctag tttcctgaaa aagaaggcag cagaatagag ggcttgtcta tgaaatcgga
     9481 attacgcaag caagtcttgc atgaaatgaa ggctatatct caagaacaaa aacagtttat
     9541 agatcaaact ttaaccgagc ggcttttaca ccatcccttc tatcaagaag ccaaggtcat
     9601 cgcaacctat ctctcttttc ctcatgagtt tcaaacgcag gaactgattg agcaggcgct
     9661 gaaggacggc aagaaggttt taatacccaa aacttatccc aaggggcgca tggactttgt
     9721 ggtctatgat ccgcaacagt tggtaaaaac ttcctttgga ttactggagc cacagggaga
     9781 tttggaagtg gtggatgcat ctcagattga tttgattcat gttcctggcc tggcttttac
     9841 gacgaaagga tatcggatag gatacggtgg aggctattat gaccgctatc tggaacattt
     9901 ttctggtcgt actttgagta cgatatatcc ttgtcaaatt caggacttta tacctgaatt
     9961 tgacaaggat attcctgttc aggaggtatt aattgatgaa ggaaatcttt gatagacgtt
    10021 accctgtgac gagtttcttc ctcttagtga cggccttggt atttttacta atgttggtca
    10081 ctgcaggcgg aaactttgac agggcagata cattatttcg atttggagcc atgtatgggc
    10141 cagctattcg cctctttccc gagcaggttt ggcgtctctt gtctgccatt tttgttcata
    10201 ttgggtggga acatttcatt gttaatatgc tttcacttta ttatcttgga aggcaggtag
    10261 aggagatttt cggttctaag cagtttttct ttctctatct cttatcagga atgatgggca
    10321 atctctttgt ttttgtattt agtcctaaat ccttagcagc aggcgcctct acctctcttt
    10381 atgggctatt tgccgcgatt attgttcttc gctatgcaac tcgcaatcct tatatccaac
    10441 agctagggca atcctatctg acactttttg tggttaacat tattggaagt gttctgattc
    10501 caggaatcag cctagcaggc catatcggtg gtgcagttgg tggcgcattt ctagcagtta
    10561 tctttccagt tagaggagaa aaacggatgt ataacaccag ccagagatta ggagcggtag
    10621 tcttgttcgt aggactcgcc attttgcttt tctacaaggg aatgggaatg tgacgactaa
    10681 tactcaatga aaatcaaaga gcaaactagg aagctagccg caggttgctc aaagcactgc
    10741 tttgaggttg tagatagaac tgacgaagtc agctcaaaac atggttttga ggttgtagat
    10801 gaaactgacg aagtcagtaa ccatatatac ggtaaggcga cgctgacgtg gtttgaattt
    10861 gattttcgaa gagtataata tgtaaacttg aataagaaaa aagctactta aaaaatgagt
    10921 agcttttaat gtgttttgga accattcgaa acaacacagc tctaaaatag ttattagcgt
    10981 tgtggaggtt ctgcaatgcc tcccccagtg tttccaagat aattcccatt ttcgtcaaac
    11041 acatctccat tgctctcatt atgataagta tctcttacat gtccactagc atcaatattc
    11101 ttatattttt tatagtagcc attatttgct ccgctgtttg aatttctaga tgaatattgt
    11161 tctgatgatc caccatttgt tgaactatct cctgaaccag aataatcttg acctccataa
    11221 ttattcgaat atccattagt ttgttcagat gaactataat ctacatttga attggaagat
    11281 ccattataag actcattaga agcaccacta gaagaattac tttgactaga agattccttt
    11341 gctttttcag cagctttttc ttcttctttc ttcaaaagtt cgatttgttt ttgatattta
    11401 tcaacaagat catttagaga tttaagagtt tcttccaaat tctcttgttt aaaagtttca
    11461 tcaacttttt tgataaaatc aatttgtttt gtaatttctt tcacatttgt ttcaagagtt
    11521 gctttatctt taaacttctc atcagaatct ttaacatcat aagccaaacc tttttgcaaa
    11581 tgaaaatcta caattgcttt agatgattct ttgactttgt tattaagata gtctttacct
    11641 gcatcggttt taagtgaagt ttcagatagt tcttttaatt tagaaataga ttcatctgaa
    11701 gatgcatcaa atgattcaaa tagtttatca acttgttctt tgtctgattt gctatctttt
    11761 tctaattgta caatttttgc ttgttgttct gcttgttgtt ggttatatga ataccatcca
    11821 aaccctaata ccaatacaac accaactgca actgatgaaa tgattacttt tttattgttt
    11881 tcgataaatt ctacaaattt gttctccata atcttttact ttgatagtgt ccgcaattac
    11941 tttaaaatta aaattacacc tatctttctc ccttattata tttttattaa tagcttccac
    12001 aaaattaaac aacttatgtt cggctcggtt gatttaattt aaccatgact actccaacag
    12061 ttaagtcaaa tttaaaatta tttattattt tggaaccatt agaaacaaca cagcaaagtt
    12121 aaaataaggc tttgtccgta cacaacttga aaaagtgcgc accgattcgg tgcttttttg
    12181 ttttactata ctaatttatt ctactcttat tttaatgaaa aaacaaatac aagtatagcg
    12241 ttttcattag tttttattaa ataggtagat tcaagtagag aatttactta atttatgtgt
    12301 ggctaatctt tatataaatg attttgttat tccttctcag tcaattcttt tccaagttgg
    12361 atgaggtaat tcttcaaatc atctttgact tgtgggtgtt tgagggcgta gtcgatggat
    12421 gttttcatga agccaaactt gtctccaacg tcgtaacgag ctcctgtaaa ttcacgggca
    12481 aaaacacgct gtgttttatt aagagtatcg attgcatcag taagttggat ttcatttcca
    12541 gcaccaggag cttgcttttc gagaatctca aaaatttcag gcgtgaggag gtagcgtccg
    12601 ataatagcaa ggtcgctagg agcgtcctct ggagctggtt tttcaacaaa ggtttcaaca
    12661 ctgtaaagac catcttttcc ttcgccttgc ggagcaataa ccccgtaagc agatacttcg
    12721 tcatgaggga ctggcatgac agcgatagta gacgcgtggg tacgctcgta gtcatccatg
    12781 agttgtttgg taagtggaac agccttttcg tctgtgatat ccatcaagtc atcaccaagc
    12841 ataacgacaa aaggttcatt tccgacgaaa gccttggctt gcaaaacagc atctccgaga
    12901 ccgcgtggat gagtttggcg gataaaatgc agacgcatgc cagttgtttc atcaactagc
    12961 ttcaaaagat ctgttttccc tttttctttg aggttatatt ccaattcgaa gtttgaatcg
    13021 aagtggtcct caatagaacg ttttgattta ccagtgacaa ctagaatatc ttcaatacct
    13081 gatttgagag cttcttccac gataaactgg atagttggtt tgtctacgat tggcaacatt
    13141 tctttggcaa gggccttggt tgctggtaaa aatcgagttc ctagtccagc agcagggata
    13201 actgcctttc taacttttga tgtcataaaa atcctttcta tagagggtta agaccactca
    13261 ttttctgctt taaattcatt gttcatgatg tcataaatgg catctttgat attggttccg
    13321 tgataaataa cttggtaaat agcctgtgta atgggcatat agactccaag ttcttgggct
    13381 agttcatagg ctgctcgagt cgttgaaatt ccttcgatta ccatgcccat attagcttct
    13441 atatcagcta gggattctcc tcgtccgaga gcatctccag ctctccagtt acgagagtgg
    13501 atggaagttc ccgttacgat caaatctccc acaccagata agccgctata ggtcaatgga
    13561 ctggccccga gtgctacccc taggcgggtg atttctgcta aacctcgagc gatgatggct
    13621 gccttagcat tatcaccaaa tccaagacca tgtaaagctc cagcaccgac agcaataata
    13681 tttttaagag caccagcagt ttcaaccccg ataacatccg tattggtata aagtcggaag
    13741 tagtgattac taaatagctt ctgaacgtat tgagctgttt gtaaatcttt agaagcagca
    13801 gttattaaag ttaggtcacg cacaatggtc tcttctgcat gactaggccc tgaaacaacg
    13861 acgatatcac tacggagatg ttcaggaatt tcttcttcaa gaatggttga taatcgttta
    13921 tggctatcag gttctaatcc ctttgatgcg tgcatgatga taaccttatg gtccaaggtt
    13981 tgtgcaactt gctgggcaac aagtcgtgtc acttttgttg ggacaacaaa caaaatcgca
    14041 cccacatttt tcaatgtttc tgctaagtcg gtgtaggcaa tgatattttc gtctagaacg
    14101 acatctttaa agtagtgctt attagtatgg tgtgtattaa tttcattgat ttgctcggga
    14161 agatttcccc aaatacgtac ctcgtgtcca ttgtcattta agacttgtga aagggcggtt
    14221 ccccaagaac caggccccaa gacggcgacg gtttgttttt ccatgatttc ctccttgata
    14281 gagttctttc tcttattcta tcatattcta ggggattttg cacttgcatt actggggtat
    14341 ggtggaaaaa tacacaaaaa ccgagacgaa gggataaact cttagtcttt agttaaagtg
    14401 agaagaaatc tgatagatag tttgattcag tatatgctta taatagaggt aaacaactca
    14461 ggaggttctt gtaggttgcg agagtttggc gaaaaaatta aaagattacg tttggctaaa
    14521 aaaatcagtc gttcagaatt ttgtggtgat gagtctgaat taagtatccg tcaattaatt
    14581 agaattgaaa atggagaatc cagaccaaca ctaacaaagt taaaatatat cgctgaacgt
    14641 ttgggggttg aagattacaa gttgatgcca agttatatag agttggataa ggaataccta
    14701 gaattgaagt atttcttgat gagaactcct acatacgaag atgaaactat cgcccaaaag
    14761 aaagagagtg ttttgataag atttttgaag agtattatga taggctacct gaggaagaaa
    14821 gatttatcat cccaaattat tcatatctgg cactaacgaa ctacacagtt caaaaattac
    14881 cagaaaagct agttgaaata ctgtccttct ggtgattttg cttaatttct gatgttcgag
    14941 acataattga ggagatttgt cttgattttt tcctaaaaaa gggtagactc ctcccttggt
    15001 ttgatgctcg atttttaaaa taaggtgact tattctgtta ggcatgtttt cccctgccct
    15061 ctagctctat atggaacagg gagtatcaga tttatctggc agattgtatc aaataaggct
    15121 tgaaactgtt ttgaataggc gtatagactt gagaatttga gaatatgtcg tctagcagta
    15181 gagacatatt ttccggcaat atgaaggaag agacgtcgaa aacgcttgat agtcaaggcc
    15241 tttacttcat caccagctag ctgctttaaa aagaggtaga gattataagc cagacagccc
    15301 atcatcatac gtacttcatt cttaatcatg gtcgaactat ctgtcttatc cccaaagaat
    15361 cctgctttcc tttctttgat aaagttttca gcattccctc gttcacgata gaattgaaac
    15421 agctcctcac tatctacact gcttaaattg gtcaaatgaa cttttttaca accataaaaa
    15481 agagcactta atcgtactct tctcttttaa ggattaaagg attagttgaa ttaattcaaa
    15541 tccactagtt ctcctgtttc taggtagact aggcgttcac aaatgttagc aatgtaatca
    15601 gcgaagcgtt ccagatgccc tatgatataa aggtattgtg ttccattggg aattgaggtt
    15661 tcttggtctt tcataagtcc aatgatttcc tttgataagg cataataata ttggtcaatc
    15721 tgttcatctt tttgagcaat actaatagct tttgaggctt ggtgcaaagg aaaggcaacc
    15781 aataaatcgg ctagcatgct gagggataat ttacccattt ggtgtaactg ttcttcgtca
    15841 ggggctagtt gattttcttt tagttgcaaa acagctttgg caatgcctgc catatggtct
    15901 cccatacgtt caaggtctga acaagaagac atgatgctaa tcacaaatcg aaggtcagac
    15961 acttgtggct gctgcaaggc caacaaacgg gcacaggtca attcgatagc gctttgacct
    16021 tggttgatag catgatcctt attgataatt agctctgcca tctccttgtc tttggaggct
    16081 aaggccagta aggcttttga agctgtttca aggacaagtt gccctagtcc taaaaaggat
    16141 tgttctaatt catgcaattc taagtcaaat tgatttctca taggtttttc cttccttatc
    16201 cgaaccgtcc tgaaatatag tcttctgtgc gctgatcttt tggattggta aacacgtcaa
    16261 cggtatctcc aaattcgcaa atttctcctg ttaagaaaaa agcagtttta tctgaaatac
    16321 gtgaagcttg ttgcatgtta tgggtaacaa tgataatcgt ataatccttt tttagttgct
    16381 gaatgaggtc ttcaattttt aaagtggaga tagggtctaa ggctgaagtc ggctcatcca
    16441 ttaacagaat atcaggttct actgctaaag ctcgcgcaat gcaaaggcgt tgctgctgac
    16501 cgccagataa ggacatggca ctctttttaa gatcatcttt gacttcttcc caaatggctg
    16561 ccccttttaa agatttctcc actaaggcat ctaattgttt tttgtctcga ataccatgtg
    16621 tccttgggcc ataagccacg ttatcataga tagacatggc aaagggatta ggctgttgaa
    16681 aaaccatccc tacacgctta cgtagctgat taaggttgaa tttgctacta taaatatctt
    16741 gctcatctaa gaggacttgg ccttcaatat ggcaagaagg aaccaaatcg ttcatccggt
    16801 taagggtttt tagaaaagtt gatttgccac aaccagatgg gcctatcaag gcagtaatct
    16861 gtctttctgg taattgaatc gaaatatttt ttaaggcttg aaaatccccg taaaataagt
    16921 ctaggtgtct gactgaaaat gttcccatac taggaagctc ctttcacaag ttttcgagat
    16981 aataagcttg atagagtatt tatcattaaa acagtaataa tcaaaatcac gccggtagca
    17041 taggcttcat tgacatgtag cccctcactt gacagcatat acatatgtag ggctagagaa
    17101 cggcctgaag acatgagact acttggcgta ttggtagagg tacctaatgt atacatgagg
    17161 gcagctgttt caccaacgat acggccaata gctagtatca ctccagctaa aatacctggc
    17221 atggcaactg gtagaacaat tctaaaaaca gtccgtaact tacctgcccc aagtccataa
    17281 cttgcttgac gcatgctatc actaacagat aaaagggctt cttctgttga gcgaataatg
    17341 actggcaaca ccatgataac tgaggttaag attcctgata acagagagta ttgaaaacct
    17401 aagaagacta caaagaagag catgccaaac agaccaaaaa caatggaagg aatcccagat
    17461 aaggtatctg aggccaatcg catgatttta acacaaaggg aatctttttt tgtatattcc
    17521 acaagataaa aaccagcaaa aatccctatg ggcaaggcta aaagaagagc accaaagacc
    17581 agaataacgg tggaaataat cgctggcata agggaaatgt tctcagaagt ataagtccaa
    17641 gaaaagaggg atagacttag atgaggtaag cctttgatga ggataaaacc aatgattaaa
    17701 aagagagagc caaaggttaa agctgaaaaa caataaacga gaagttttag caggtattta
    17761 ctcataagat gattttcctt tcaagtaggc aaagtaggca ttaatcaaga gaataaggaa
    17821 aaagagaact gctgaggttg caataagggc ttccctatgc tgacctgatg cgtaagccat
    17881 ttccagaaca atattggttg ttaaggttct ggttcctgaa aagagtccac ttggaataat
    17941 cggctggttg cctgccacca aaataactgc catggtttca cctactgcgc gaccaattcc
    18001 taaaataact gctgataaaa taccagatct cgcagctggc aagatgacac taaaaatact
    18061 ccgttcatga ctagctccta gagccaagct accagaataa tacgttttgg gaactgttcg
    18121 gatagcagat tctgacaaac tgataatggt tggcaaaatc attattccta atagtaacga
    18181 agcggttagg acactcatgc catttcctaa aaaggttcta atccaaggca ccaataattg
    18241 taggccgaaa aaaccataaa caatagatgg aatggccgcc atcaagttga tagctgattt
    18301 taagaagcca tagacgggct ttggacaata ataaaccata aacaccgatg tcaagatgcc
    18361 tgttggcacc ccaatcacaa tcgctcctaa ggtaattaat aaggaaccaa cgatcattgg
    18421 taaaatacca tagcttgccg gaatgttcgt tggcgaccaa tcactgccta ataaaaaacg
    18481 ggcaaagccg tagttagcca tgaaaggtaa gccattacta aaaataaaga aacagattag
    18541 caaaatagct acaacagcta ctgttgcact catgaaaaaa attgccctaa aaactgcttc
    18601 tttgaaggct tgttttgtca catcttgtcc tttctagtga agaaagtaag ggagatacga
    18661 cacctcccta cttgccttct ttatcttatt gtacgatgaa acgtctgcat ctctttagag
    18721 atttatggag caaacatttt atttaatctt gtcccaggtg gttaatttgc cactaaaaac
    18781 gtctgcaagt tcagccatac tgacttggct tgccttattg tcattattga ccacaacagc
    18841 aataccgtct aaagcaatag catcatgggt gagactctta ccttcttcag gagttagttc
    18901 cctagaaacc ataccaatat cagcggtttt ctccttaaca gcggtaatac ctgctgaaga
    18961 cccattagag gtaatatcaa tcgtaacttc tggattttct tttttataag cttctgctaa
    19021 tttttccatt aaagaagata ctgaagtgga acctacaaca gacaacttgc ctgataagtg
    19081 ttggcttgta tattctgtgg tttcggtttt agattcaata aatttattat ctgtgaccac
    19141 ttgttgacct tgtttggagt ggataaagct gataaaatct tgacctagct tggaaagatt
    19201 agaagaccaa acaatgttga agggacgttg aagagggtat tcaccatcta aaactgtgtc
    19261 tcgactagcc ttgacaccat caatctctaa agccttgaca gatttcgtta aagatcccaa
    19321 ggagatgtag ccgatagcat tagcattccc ttgaactgct gagagaacac cttctgtact
    19381 attttgaatc acagctgttt tggcagtgtt gtcaattttt ttatcaccgt cttttttgag
    19441 aatccctgtg atttctgtga aggcaccccg tgttccagag ccattttctc gtgaaatcac
    19501 ctcaatcgtt cctgaagctg actgtttgga agcagctgac tgattgccac aggcaacaag
    19561 cccaaatcct gataagccaa tggctgcaag agtaagcatt tttttgaatt tcataataat
    19621 cacctttatc tctatgtatt tttcttgtgt aggcttacta catttatagt ctaacaagtc
    19681 tttgtaaagg tttatccctg attcatgtaa agattgtgta aagaatcaaa aaaagccact
    19741 tttgaaaaat ggctgctcct aaaaatagct ttaaaaatta ttagtcctgt gcgaaagatt
    19801 ggttaggaag aaaaatcgtg aagcaactgc ctctgccaag ctgactcgtc accgtgactt
    19861 ggccacctaa taattgactg agttctttga caatggcaag gccaagacca gtgccaccag
    19921 tttgtctgct tcgaccttta ttaactcggt aaaaacgttc aaaaatacga tcctgctcta
    19981 attgactaat accaatccct gtatctgata cagaaatctt aatgccttcg ttcacctttt
    20041 gggtcttgac ctcaattttc cccccttgtt cagtgtaacg gatggcattg gataaaagat
    20101 tgagtaagat ttgggaaagt aattgactat ctgatacgag ggtgacatca tctggcacct
    20161 gcacctttag ctgtaaatcc ttcttcttga gctgaggttg caagctttga gtcaaatcct
    20221 gtacaaattc tgccaaagaa agggtcgtcc attgtatagg catttgttga gccttagata
    20281 aggtaagaag atgctcaaca atatgctcaa gacgcaaact ttctttgtaa ataatgtcta
    20341 gaaagtcatc cttgagcgct tcttcttcag ctgacatccc cttaatggtt tcagcaaagc
    20401 ccttaatcga agtaactggt gtcctcaatt catgggaggc atttgagaca aaggctaaat
    20461 ttaacttttc ataagttcta atcgttgtta aatcatatag caagacgagc acagcttcca
    20521 cagattgggt ggggctaaaa acgggaactg ctgtcacttc taaaatcaag tcaccctcat
    20581 gaaacccact tacttcttgt tttaaccttg ttttttgatc aaaggcttgg tgaactaaat
    20641 tccgaatatc catccgtttg aggtcatcaa gtgaacttat gtcgccgtcc acatcgggaa
    20701 aataatgagg cagagagcga ctggataata acatctgacc ttgagcggaa actaaaaacg
    20761 tccccatggt taggtgcgac agaagaacct ccattgtttc ggctaggtcc ttgtattgct
    20821 gatcctgttg ggagactttg gtttttaggg cagacacata ctgagccaaa gactttaagt
    20881 cttcttgccc tttttctaaa aagtattcac tactggtcaa gagaggttgg tgcaaggtct
    20941 caaaagcaac ttcccatttc caaaggcaaa agagccagta gccaccttgt cccaaagaaa
    21001 gggctagaag aaagagaccg atgcctttac tgatccaagt taatgccatc cctgcaatca
    21061 gaatgaggct aacacttaga ttgactagcc aaaattgaag gtagcgtttc atctataact
    21121 ccttgaactt ataaccataa ccccgaatgg ttcgaataaa ttgaggggct ttaggattgt
    21181 cttcaatttt ttccctcaac ttaccaatat gaacgtccac caaacgtgtt tcctgcccaa
    21241 agtcataccc ccagatacgt tccaaaagac gctctctagt cagtgtcatg ttgggatgtt
    21301 tcataagata gagcaagagt tcaaattctt ttggggtcaa actcagtaac ttattcgcct
    21361 tgtagacttc atgacgctca gggtatactt tcaaggtccc aaatagccaa gaatcgtcag
    21421 cgatattatc tgaatcatct ccttcttgtt ctcctttagt tcgcctgagg acagccttga
    21481 cacgcgccag caattctcta gggctaaaag gcttggtcag gtagtcatca gcccctaatt
    21541 ccaaggccaa aaccttatca aattcatcac ttttcgcaga aaccatcata attggagttt
    21601 tgacgccttt ggctctcagc cgcttacaaa cttccatgcc atctaattgt ggtaacatga
    21661 tatcaagcaa gataaaatca aagggttctg tttctgccaa agctaaggcc ttccgtccat
    21721 ttgttaccaa ttgagtagaa aagccttcct tacttaaatg gtagtcaagc aatttcagaa
    21781 tgtgttcttc atcatccact aataagactt gttttgtcat ctattatctc ctattggtaa
    21841 cattataaca caattatcag aaatcctaac attgctaaat cagattaaat ttgcttatca
    21901 agactagtat ctggtcaaac gctcaatcat ctccttgtgc tctggatagg tcgccagtag
    21961 atctaccctt tcaaataatt caaaatcctc aaattcaaaa ccaggagcaa caagacaaga
    22021 aaccagagca tcatccttat caactgttga tccccaaata gtgcccttag gaacacagta
    22081 gtgaagttgt tgccctttgg atatgtccag gcctaaagtg actgtttcgt agtgaccatc
    22141 tgctgtaatc atgtgaacag taagtgggga tcctgcatga aaataccaga tttcatctgc
    22201 tgtcaatcgg tgaaaatgtg aaggattcgt ttcttcttaa taagaaataa atactggtat
    22261 aaagcgccct tcccttacca gcaaggttta tagtgtctga agcttttttt gtttgtctaa
    22321 catagccacc ttcaacatgg ggagctaact ctagagttct tatcaagtct tctttatccg
    22381 tcggagccaa tgggttgaag taactcttgt tcaaagtggt gttacgattt caagaactcc
    22441 tctcagctct gaggacacgg taatgattga tgcgacggaa gtacaaatca atcgccctaa
    22501 aaaaagaatt agcgaatgat tctggtaaaa agaaatgcca cgctatgaag gctcaagcga
    22561 ttgtcacaag tcaagggaga attgtttctt tggatatcac tgtgaactat tgtcatgata
    22621 tgaagttgtt caaaatgagt cgcagaaata tcggacaagc tggtaaaatc ttggctgaca
    22681 gtggttatca agggcccatg aagatatatc ctcaagcaca aactccacgt aaatccagca
    22741 aactcaagcc gctaacagtt gaagataaag cctgtaacca tgcgctatcc aaggagagaa
    22801 gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatgatttca acaacctatc
    22861 gaaatcatcg taaacacttc ggattacgaa tgaatttgat tgctggcatt atcaatcatg
    22921 aactaggatt ctagttttgc aggaagtcta ttatttggtt aggtgaatta gtgaagcgtt
    22981 taggcaagtg tctctggtta cgacgtcatg acctctaaat cgattatatt taggggtcat
    23041 gactagtgaa gcagttagct agttcgcata taagcggcta gcgtctaaca attaggaact
    23101 ttagttccaa taactttaag attacgacgt tttaggacat aaatcgatca tatttatgtc
    23161 ctaaaactag tgaagcgcct agccaaagtc cgaataggat ttggcgttag ttacttagat
    23221 tgctttgcaa tcaagtaact ttggcgattt acatcttctc tggcgcttct actccaagca
    23281 agcgaagggc ttctttgaga acgactgcgg ttgcgtagct gagggctaga cggctgtcgc
    23341 gttctgggct ttcatccaag atacgtgtat gtgcatagta tttgttaaag gattgagcca
    23401 ggctaattgc aaatttagca atgatagaag gttcaaagtt atctgccgca cggttgataa
    23461 tacgtgggaa gtcttgaatg agtttaatga tttcccagct ttcagtatca ttcaagctat
    23521 agttgccagc tgtttctggt ttgaaatcgg ctttgcgtaa gatagattgg atacgagcgt
    23581 aggcatattg aacgtaaggt ccagtttcac cctcgaagga taccatagcc tctaggtcga
    23641 agtcgtatcc atttgtacgg tcggttttga ggtcatagaa tttaatggct ccaaccccaa
    23701 cagcatgtgc tacctgatct ttattttcca attcaggatt tttagcctcg atttggacct
    23761 tggcacggct aacagcctct gcaacagtag gctctagcaa gatgacattc cctttacgag
    23821 tagagagctt cttcccttct tttgtaacca agccaaaagg aacgtgagta atgtcgtcac
    23881 tccagtcgta gcccatctct tgcaagacag ctttgagctg tttaaagtgg gcagattgtt
    23941 cttgaccaac gacatagata gatttagcaa attggtattc gtttttacgg taaagggctg
    24001 cagccaagtc acgtgtgata tagagagttg caccatcaga cttcttgatg agggctggat
    24061 gttcaattcc gtatttctca agattcacaa cttgggcacc ttctgattca agaagtagtc
    24121 ctttttcaga aagaatgtct acaactgcat ccatcttatc attgtagaag gcttctccgt
    24181 tatagctgtc aaattcaacc ttcaattcat tgtaaaggcg gttaaattcc actaaacttt
    24241 catcgcggaa ccattgccaa agagcgagag cttcctcatc ttcattttca agtttacgga
    24301 accattcgcg cgcttcttca tccaagctag ggtcattttc agcttcagcg ttgatgcgga
    24361 catagagttt aaggagttca tcgattggat gagcttttac agcttcttcg tcgccccatt
    24421 ttttgtaggc aacaatcaac atcccaaatt gtttacccca gtctcccaaa tggttgacct
    24481 tgaccgtttg ataaccgatt ttttggaaaa tatgtgacaa gctatctccg ataacagttg
    24541 aacgcaggtg gccaatagaa aatggtttag cgatattcgg actagacatg tcgataacaa
    24601 cattttcttg tttgccaata ttttggtcag catagtgttc tttttcagtg gtaacagctt
    24661 gcaatacttg agcagaaatg gcagatttat caaggaaaaa gttaacgtaa ggtcctgttg
    24721 cgacaacttt ttcaaaggct tggctgttca ttttttcagc cagttcagcc gcaatcattt
    24781 gtggtgcttt acgttcgact ttggcaagag aaaaagcagg gaaagcgatg tcacccattt
    24841 ctgagttttt aggggtttcc agtaacttta aaatagcctc ttggtccagg ctatcaatga
    24901 tgctagccaa ttcgctagca atcaattctt ttgtattcat taagagctcc tttttggact
    24961 tttctactat tttaacacaa ttttaaagaa agaagaaaaa atttttgaaa tctcctgttt
    25021 ttttggtata atatggttat aaatatagtt ataaatatgc acgcaagagg attttatgag
    25081 aaaaagagat cgtcatcagt taataaaaaa aatgattact gaggagaaat taagtacaca
    25141 aaaagaaatt caagatcggt tggaggcgca caatgtttgt gtgacgcaga caaccttgtc
    25201 tcgtgatttg cgcgaaatcg gcttgaccaa ggtcaagaaa aatgatatgg tgtattatgt
    25261 actagtaaat gagacagaaa agattgattt ggtggaattt ttgtctcatc atttagaagg
    25321 tgttgcaaga gcagagttta ccttggtgct tcataccaaa ttgggagaag cctctgtttt
    25381 ggcaaatatt gtagatgtaa acaaggatga atggatttta ggaacagttg ctggtgccaa
    25441 taccttattg gttatttgtc gagatcagca cgttgccaaa ctcatggaag atcgtttgct
    25501 agatttgatg aaagataagt aaggtcttgg gagttgctct caagacttat ttttgaaaag
    25561 gagagacaga aaatggcgat agaaaagcta tcacccggca tgcaacagta tgtggatatt
    25621 aaaaagcaat atccagatgc ttttttgctc tttcggatgg gtgattttta tgaattattt
    25681 tatgaggatg cggtcaatgc tgcgcagatt ctggaaattt ccttaacgag tcgcaacaag
    25741 aatgccgaca atccgatccc tatggcgggt gttccctatc attctgctca acagtatatc
    25801 gatgtcttga ttgagcaggg ttataaggtg gctatcgcag agcagatgga agatcctaaa
    25861 caagcagttg gggttgttaa acgagaggtt gttcaggtca ttacgccagg gacagtggtc
    25921 gatagcagta agccggacag tcagaataat tttttggttg ccatagaccg cgaaggcaat
    25981 caatttggcc tagcttatat ggatttggtg acgggtgact tttatgtgac aggtcttttg
    26041 gatttcacgc tggtttgtgg ggaaatccgt aacctcaagg ctcgagaagt ggtgttgggt
    26101 tatgacttgt ctgaggaaga agaacaaatc ctcagccgcc agatgaatct ggtactctct
    26161 tatgaaaaag aaagctttga agaccttcat ttattggatt tgcgattggc aacggtggag
    26221 caaacggcat ctagtaagct gctccagtat gttcatcgga ctcagatgag ggaattgaac
    26281 cacctcaaac ctgttatccg ctacgaaatt aaggatttct tgcagatgga ttatgcgacc
    26341 aaggctagtc tggatttggt tgagaatgct cgctcaggta agaaacaagg cagtcttttc
    26401 tggcttttgg atgaaaccaa aacggctatg gggatgcgtc tcttgcgttc ttggattcat
    26461 cgccccttga ttgataagga acgaatcgtc caacgtcaag aagtagtgca ggtctttctc
    26521 gaccatttct ttgagcgtag tgacttgaca gacagtctca agggtgttta tgacattgag
    26581 cgcttggcta gtcgtgtttc ttttggcaaa accaatccaa aggatctctt gcagttggcg
    26641 actaccttgt ctagtgtgcc acggattcgt gcgattttag aagggatgga gcaacctact
    26701 ctagcctatc tcatcgcaca actggatgca atccctgagt tggagagttt gattagcgca
    26761 gcgattgctc ctgaagctcc tcatgtgatt acagatgggg gaattatccg gactggattt
    26821 gatgagactt tagacaagta tcgttgcgtt ctcagagaag ggactagctg gattgctgag
    26881 attgaggcta aggagcgaga aaactctggt atcagcacgc tcaagattga ctacaataaa
    26941 aaggatggct actattttca tgtgaccaat tcgcaactag gaaatgtgcc agcccacttt
    27001 ttccgcaagg cgacgctgaa aaactcagaa cgctttggaa ccgaagaatt agcccgtatc
    27061 gagggagata tgcttgaggc gcgtgagaag tcagccaacc tcgaatacga aatatttatg
    27121 cgcattcgtg aagaggtcgg caagtacatc cagcgtttac aagctctagc ccaaggaatt
    27181 gcgacggttg atgtcttaca gagtctggcg gttgtggctg aaacccagca tttgattcga
    27241 cctgagtttg gtgacgattc acaaattgat atccggaaag ggcgccatgc tgtcgttgaa
    27301 aaggttatgg gggctcagac ctatattcca aatacgattc agatggcaga agataccagt
    27361 attcaactgg ttacagggcc aaacatgagt gggaagtcta cctatatgcg tcagttagcc
    27421 atgacggcgg ttatggccca gctgggttcc tatgttcctg ctgaaagcgc ccatttaccg
    27481 atttttgatg cgatttttac ccgtatcgga gcagcagatg acttggtttc gggtcagtca
    27541 acctttatgg tggagatgat ggaggccaat aatgccattt cgcatgcgac caagaactct
    27601 ctcattctct ttgatgaatt gggacgtgga actgcaactt atgacgggat ggctcttgct
    27661 cagtccatca tcgaatatat ccatgagcac atcggagcta agaccctctt tgcgacccac
    27721 taccatgagt tgactagtct ggagtctagt ttacaacact tggtcaatgt ccacgtggca
    27781 actttggagc aggatgggca ggtcaccttc cttcacaaga ttgaaccggg accagctgat
    27841 aaatcctacg gtatccatgt tgccaagatt gctggcttgc cagcagacct tttagcaagg
    27901 gcggataaga ttttgactca gctagagaat caaggaacag agagtcctcc tcccatgaga
    27961 caaactagtg ctgtcactga acagatttca ctctttgata gggcagaaga gcatcctatc
    28021 ctagcagaat tagctaaact ggatgtgtat aatatgacac ctatgcaggt tatgaatgtc
    28081 ttagtagagt taaaacagaa actataaaac caagactcac tagttaatct agctgtatca
    28141 aggagacttc tttgacaatt ctccactttt ttgctagaat aacatcacac aaacagaatg
    28201 aaaaggagct gacgcattgt cgctcccttt tgtctatttt ttaaggagaa agtatgctga
    28261 ttcagaaaat aaaaacctac aagtggcagg ccttggcttc gctcctgatg acaggcttga
    28321 tggttgctag ttcacttctg caaccgcgtt atctgcagga agtattagac gccctcctta
    28381 ctgggaaata tgaagctatt tatagtatcg gggcttggtt gattggtgtg gccgtagtcg
    28441 gtctagttgc tggtggactc aatgttgtcc tcgcagccta tattgcccaa ggagtttcat
    28501 ccgaccttcg ggaggatgcc ttccgtaaaa ttcaaacctt ttcttatgct gatattgaac
    28561 aatttaatgc gggaaatcta gtcgttcgaa tgacaaatga tatcaaccag attcagaacg
    28621 ttgtcatgat gaccttccaa attcttttca gacttcccct cttgttcatc ggttcgttta
    28681 tcctagcggt tcaaacctta ccttctctgt ggtgggtgat tgttctcatg gtagtcttga
    28741 tttttggttt gactgctgtc atgatgggaa tgatggggcc tcgttttgcc aagtttcaaa
    28801 cccttcttga gcgcatcaat gccattgcca aggaaaattt acgtggcgtt cgtgtggtca
    28861 agtcctttgt ccaagaaaaa gagcaatttg ctaagtttac agaggtctca gacgagcttt
    28921 ttggtcaaaa cctttacatt ggttatgcct tttcagtagt ggaacccttt atgatgttgg
    28981 ttggttacgg ggcggtcttc ctctctattt ggctggtcgc gggaatggtt cagtcggatc
    29041 cgtctgttgt tggttccatc gcttcttttg ttaattacct aagccagatt atctttacca
    29101 ttgttatggt tggatttttg ggaaattctg tcagccgtgc catgatttcc atgcgtcgta
    29161 ttcgagaaat tcttgacgca gagccagcta tgaccttcaa ggatatccca gatgaagagt
    29221 tggttggaag ccttagcttt gaaaatgtga cctttaccta tccaatggac aaggaaccga
    29281 tgctgaaaga tgtgagcttt actattgaac ctggtcaaat ggttggtgta gttggagcga
    29341 ctggtgcagg aaagtcaacc ttggctcaat tgattccacg tctctttgat ccacagaacg
    29401 gggccattaa aatcggtggc aaggatattc gagaagtgag tgaaggaacc ctgcgtaaaa
    29461 cagtttccat cgttctccaa cgtgccattc tttttagtgg aacgattgca gataacttga
    29521 gacaggggaa gggaaatgct actctatttg aaatggagcg cgcagccaat attgcccagg
    29581 ctagtgaatt cattcatcgt atggagaaaa cctttgaaag tccagttgaa gaacggggaa
    29641 ccaatttctc tggtggacaa aaacaaagga tgtcgattgc gcgtgggatt gtcagcaatc
    29701 cacgtattct gatttttgat gattcgacct cagccttgga tgccaaatca gagcgcttgg
    29761 tgcaagaagc tttgaataag gacttgaagg ggacgacaac cattattatt gctcaaaaaa
    29821 ttagctcggt tgtccatgca gacaagatct tggttctaaa tcaaggacga ttgattggtc
    29881 aaggtacgca tgcagacttg gttgccaaca atgccgttta ccgtgaaatc tatgaaacac
    29941 agaaatgaaa gacaaactat aagaaaagtc aatagtttta tctaaactat ttcttatttc
    30001 aatttgatga tttggcgatg attttagagc acggcaaaag gcccttgaaa aagtccattt
    30061 tttcaaaggt aatcctgtgt taatttcaga aattacatca ctttttgttc gtcaaatggc
    30121 agctcttttt taggatataa aacagggttc ggataagttt ttttgcaagg tggatgatgg
    30181 ctacattgta atgttttcct tattctaact tagtcttaag ataggcctta aaagcaggtg
    30241 aaaagcgagc gcatgctttg gcagcttgta tgagtgccta ccgcagatga ggggaacccc
    30301 gtttgatcat tcttccagct aaatcaatct gacctgactg ataaatagaa gaatccagtc
    30361 cagcgaaagc ttgtaattga gcaggattat caaaggcatg aatattttga atctcggcta
    30421 aaatgaccgc ccctaaacga ttcccaatcc cagtaaccgt cgtgatgacc gaatttaact
    30481 cagccatcaa gtcattgaca catttttccg ccttgtcaat gagcctcttg taatgtttga
    30541 tgttttcatt acacgagata aaacgtctat gcgttatcaa actcattacc aattaaaaca
    30601 aatgtggtta gatcctttcg gaaattgtca agcgattgga ggaaatgaac taatccacag
    30661 cggcttattc caagtatacc acttgggctt tggcagtagc taactgcgct aaatataata
    30721 taaggaggag taaaatgaag acagttcaat ttttttggca ttattttaag gtctacaagt
    30781 tctcatttgt agttgtcatc ctgatgattg ttctggcgac ttttgcccaa gccctctttc
    30841 cagtcttttc tggacaagcg gtgacgcagc tagccaattt agttcaagct tatcaaaatg
    30901 gcaatccaga acttgtatgg caaagcctat caggaatcat ggtcaatctt ggcctgctgg
    30961 ttttggttct atttatctct agtgtaatat acatgtgtct catgacgcgc gtgattgcag
    31021 aatcgaccaa cgagatgcgc aaaggtctct ttggtaagct tgctcagttg acggtttctt
    31081 tctttgaccg tcgacaagat ggcgatatcc tgtctcattt taccagtgat ttggataata
    31141 tcctccaagc ctttaacgaa agcttgattc aggtcatgag caatattgtt ttatacattg
    31201 gtctgattct tgtcatgttt tcgagaaatg tgacgctggc tctcatcacc attgccagca
    31261 ccccattggc tttccttatg ctgattttca tcgtgaaaat ggcacgtaaa tacaccaacc
    31321 tccagcagaa agaggtaggg aagctcaacg cctatatgga tgagagcatc tcaggccaaa
    31381 aagccgtgat tgtgcaagga attcaagagg atatgatggc aggatttctt gaacaaaatg
    31441 agcgcgtgcg caaggcaacc tttaaaggaa gaatgttctc aggaattctt ttccctgtca
    31501 tgaatgggat gagcctgatt aatacagcca tcgtcatctt tgctggttcg gctgtacttt
    31561 tgaatgataa gtctattgaa acaagtacag ccctaggttt gattgttatg tttgcacaat
    31621 tttcacagca gtactaccag cctattatcc aagttgcagc gagttgggga agccttcagt
    31681 tggcctttac tggagctgaa cgaattcagg aaatgtttga tgcagaggag gaaatccgac
    31741 ctgaaaaggc tccaaccttc actaagttgc aagaaagtgt tgaaatcagt catatcgatt
    31801 tttcatactt gcctgataaa cctattttga aagatgtcag catttctgcc cctaaaggcc
    31861 agatgacagc agttgttggg ccgacaggtt caggaaaaac gactattatg aacctcatca
    31921 atcgctttta tgatgttgat gctggtggta tttattttga tggtaaagac attcgtggct
    31981 atgacttaga tagtcttaga agcaaggtgg gaattgtatt gcaagattcg gtcttgttta
    32041 gcggaacgat tcgagacaat atccgatttg gtgtgccaga tgctagtcag gaaatggttg
    32101 aggtagcagc aaaagcaacc cacattcacg actatatcga aagtttgcct gataagtacg
    32161 atactcttat tgatgatgac cagagcatct tttcagcagg gcagaagcaa ttgatttcaa
    32221 tcgctcgaac cctgatgaca gatccagaag ttctcattct cgatgaagca acttcaaacg
    32281 tagatacggt gacagaaagc aagattcaac atgccatgga ggtggttgta gcaggtagaa
    32341 ctagtttcgt cattgcccac cgcttgaaaa ccattctcaa tgcagatcag attattgtcc
    32401 ttaaagatgg agaagtcatt gaacgtggta accaccatga acttttgaag ctaggtggct
    32461 tttattcaga actctatcac aatcaatttg ttttcgaata agaaagaagt tgtcctatgt
    32521 gggcagcttt ttcttgtcca taaaaaatgt ttatcacagc cttaaaaaaa acatattaga
    32581 cgaaagtcat tttgagtgat atgataggac tatcgttagc attcgaaagg agaggcatca
    32641 tggctagaac ggttgtagga gttgctgcaa atctatgtcc cgtagacgca gaaggcaaaa
    32701 tcattcattc atctgtatct tgtagattcg cagagatcat tcgtcaagtc ggtggtctcc
    32761 ctttagtcat tcctgttggt gatgagtcag ttgtacgtga ttatgtggaa atgattgaca
    32821 aactcatttt gacaggaggc caaaatgttc atcctcagtt ttatggagag aaaaagaccg
    32881 tcgagagcga tgattacaat ctggtccgtg acgaatttga attggcactc ttgaaggaag
    32941 cgcttcgtca gaataaacca attatggcaa tctgtcgcgg tgtccaactt gtcaatgttg
    33001 cctttggtgg aaccctcaat caagaaatcg aaggtcactg gcaaggacta cctttcggga
    33061 catctcactc tattgagaca gtagaaggaa gcgtggtggc taagctattt gggaaagaaa
    33121 gtcaggtcaa ctcagtccat cgtcaaagca ttaaagattt ggcacctaat ttccgtgtaa
    33181 ctgctattga ttcaagagac caaactattg aagcgattga gtctatcgac gagcaccgca
    33241 ttatcggttt acagtggcat ccagagtttc tggttaatga agaagatggc aatttagaat
    33301 tatttgagta tttattgaat gaactgtaac gattggaaca tctggtcgtt ctttctttta
    33361 ttttttcaaa atttttagaa tgtggcattt tacgcaaacg tttgaattct gataaaaatt
    33421 ggagaaattc gacaaaaaaa cttgaaaaaa acgaaggtaa gcgttatgat agaaaagaag
    33481 aaatattgga ggaagaacat gtcacatatt aaatttgatt attcaaaagt tttagacaaa
    33541 tttgttgcac cacatgaagt ggaatacatg caatcacaag taacagcagc agatgaattg
    33601 atccgtaaag gaactggtgc tggtagcgac ttcttgggat ggttggacct tcctgaaaaa
    33661 tacgaccgcg aagaatttga ccgcatcttg aaagctgctg agcaaatcaa gtcagacagc
    33721 gatgttttgg ttgtgatcgg tattggtgga tcttaccttg gtgcaaaagc agcaatcgac
    33781 ttcttgaatc accattttgc taacttgcaa acaaaagaag aacgcaaagc tccacaaatc
    33841 ctttacgcag gaaactcaat ctcatctact taccttgctg acttggtaga gtatgttgca
    33901 gacaaagact tctcagtaaa cgtaatttct aaatcaggta caacaactga accagcgatt
    33961 gctttccgtg tctttaaaga actcttggtt aagaaatacg gtcaagaaga agctaacaaa
    34021 cgtatctatg caacaactga ccgccaaaag ggtgctgtta aggttgaagc agacgctaac
    34081 ggttggggaa catttgttgt tccagatgat atcggtggac gcttctcagt attgacagcc
    34141 gttggtttgc ttccaatcgc agcatcagga gctgacatca aagctcttat ggaaggtgcg
    34201 aatgcagctc gcaaagacta cacttcagac aaaatctctg aaaacgaagc ttaccaatac
    34261 gcagctgttc gtaacatcct ttatcgtaaa ggctatgcaa ctgagatctt ggtaaactat
    34321 gagccatcac ttcaatactt ctcagaatgg tggaaacaat tggctggtga atcagaagga
    34381 aaagaccaaa aaggtatcta cccaacttca gccaacttct caactgactt gcactcactt
    34441 ggtcaattta tccaagaagg aactcgtatc atgtttgaaa cagttgtccg tgttgacaaa
    34501 cctcgtaaaa acgtgcttat tcctactttg gaagaagacc ttgacggact tggttacctt
    34561 caaggaaaag acgttgactt tgtaaacaaa aaagcaactg acggtgttct tcttgcccac
    34621 acagatggtg atgtaccaaa catgtatgtg actcttccag agcaagacgc tttcactctt
    34681 ggttacacta tctacttctt cgaattggca attgcccttt caggttactt gaatgctatc
    34741 aacccatttg accaaccagg tgttgaagct tataaacgta acatgtttgc ccttcttgga
    34801 aaaccaggat ttgaagaatt gagcaaagaa cttaacgcac gtctataata gaagaaaaga
    34861 gtggtttgcc cactcttttt actctcttta tccatagaaa ttggactcag ccaagacttg
    34921 tgatataata tagaaagcaa aaaggcagac gcctagataa taggagaaac tatgtcaaaa
    34981 gatatccgcg tacgttacgc accaagtcca acaggactac tacacatcgg aaatgctcgt
    35041 acagcattgt ttaattactt gtatgcgcgc catcatggtg gaacatttct catccgtatc
    35101 gaagatactg accgtaaacg ccatgtcgag gatggtgaac gttcacaact tgaaaacctt
    35161 cgctggttag gcatggattg ggatgaaagt ccagaatcac atgagaatta tcgccagtct
    35221 gagcgtttgg acttgtatca aaaatacatt gaccaactat tagctgaagg aaaagcctat
    35281 aaatcttacg ttacagaaga agagttggca gctgaacgcg aacgccaaga agtagctggc
    35341 gaaacaccac gctacatcaa tgaatacctt ggtatgagtg aagaagaaaa agcagcttac
    35401 atcgcagaac gtgaagcagc agggatcatc ccaactgttc gtttggctgt caatgagtca
    35461 ggtatctaca agtggcatga tatggtcaaa ggcgatatcg aatttgaagg tggcaatatc
    35521 ggtggtgact ggattatcca aaagaaagac ggttacccaa cttacaactt tgccgttgcc
    35581 atcgatgacc atgatatgca aatctctcat gttatccgtg gagacgacca tattgctaac
    35641 acaccaaaac agctcatggt ttatgaagca cttggttggg aagctccaga gtttggtcac
    35701 atgaccttga ttatcaactc tgagactggt aagaagttat ctaaacgtga tactaataca
    35761 cttcaattta tcgaagatta ccgaaagaaa ggttaccttc cagaagcagt ctttaacttt
    35821 attgctcttc ttggttggaa cccaggtggt gaagatgaga ttttctctcg tgaagaactc
    35881 attaaacttt ttgatgaaaa ccgcctcagc aagtcaccag cagcctttga tcagaaaaaa
    35941 ctagactgga tgagcaatga ttatatcaag aatgcagacc ttgaaaccat ctttgaaatg
    36001 gcaaaaccat tcttagagga agcaggccgt ttgactgaca aggctgaaaa attagttgag
    36061 ctctataaac cacaaatgaa atcagtagat gagattatcc cattgacaga tcttttcttc
    36121 tcagatttcc cagaattgac agaagcagag cgcgaagtca tgacgggtga aacagttcca
    36181 acagttcttg aagcattcaa agcaaaactt gaagcgatga cagatgataa atttgtgaca
    36241 gaaaatatct tcccacaaat taaagcagtt caaaaagaaa caggtattaa agggaaaaat
    36301 cttttcatgc ctattcgtat cgcagtttca ggcgaaatgc atgggccaga attaccagat
    36361 acaattttct tgcttggacg tgaaaaatca attcagcata tcgaaaacat gctaaaagaa
    36421 atctctaaat aaagaggata caataatgga catctgggaa aagatgtacg aagaagcaca
    36481 gaaactatac aatccacatg aagtatcaga ctttgtttat gccaatcatg ttgtagctgc
    36541 agtagaagca gaagatggac aaatatttac aggattctgt atggagggaa cctgtggtgt
    36601 tttccatctc tgcgcagaac gggcggccct cttcaatatg taccaatttt caggacaaac
    36661 taaggttaag aaagtattag cctttcgaga caaaccacct tatggtggaa gttcagccat
    36721 gccttgcggt gcttgtagag aattcctttt agagcttaat gctgaaaata aagatgcaga
    36781 attcatgatg gactataata taagaaaaac agttaaagtc gcagaactaa tcccttattg
    36841 gtggggagaa gaacgtgctt ctaagtttaa tgagcgatag aagagtcagt ataattctgg
    36901 ctttttttac tataagttga aaaaata
//
LOCUS       DAVKXA010000017        34361 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKXA010000017 DAVKXA010000000
VERSION     DAVKXA010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.017"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            556..1008
                     /locus_tag="VW883_000910"
     CDS             556..1008
                     /locus_tag="VW883_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0274074.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1027..2364
                     /locus_tag="VW883_000911"
     CDS             1027..2364
                     /locus_tag="VW883_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0274075.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2443..3327
                     /locus_tag="VW883_000912"
     CDS             2443..3327
                     /locus_tag="VW883_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0274076.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3327..4160
                     /locus_tag="VW883_000913"
     CDS             3327..4160
                     /locus_tag="VW883_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0274077.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4178..6271
                     /gene="nanB"
                     /locus_tag="VW883_000914"
     CDS             4178..6271
                     /gene="nanB"
                     /locus_tag="VW883_000914"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0274078.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6283..7386
                     /locus_tag="VW883_000915"
     CDS             6283..7386
                     /locus_tag="VW883_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0274079.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7560..8258
                     /locus_tag="VW883_000916"
     CDS             7560..8258
                     /locus_tag="VW883_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0274080.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8277..9794
                     /locus_tag="VW883_000917"
     CDS             8277..9794
                     /locus_tag="VW883_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0274081.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9919..11247
                     /locus_tag="VW883_000918"
     CDS             9919..11247
                     /locus_tag="VW883_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0274082.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11499..12365
                     /locus_tag="VW883_000919"
     CDS             11499..12365
                     /locus_tag="VW883_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0274083.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12381..13220
                     /locus_tag="VW883_000920"
     CDS             12381..13220
                     /locus_tag="VW883_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0274084.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13493..13945
                     /locus_tag="VW883_000921"
     CDS             13493..13945
                     /locus_tag="VW883_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0274085.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14042..14386
                     /locus_tag="VW883_000922"
     CDS             14042..14386
                     /locus_tag="VW883_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274086.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIINGIVNGLIGRYIKLGIY
                     AAKYGISMVRSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14663..15307
                     /locus_tag="VW883_000923"
     CDS             14663..15307
                     /locus_tag="VW883_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0274087.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSAFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15476..16393
                     /locus_tag="VW883_000924"
     CDS             15476..16393
                     /locus_tag="VW883_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0274088.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            16411..17295
                     /locus_tag="VW883_000925"
     CDS             16411..17295
                     /locus_tag="VW883_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0274089.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17311..18162)
                     /locus_tag="VW883_000926"
     CDS             complement(17311..18162)
                     /locus_tag="VW883_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0274090.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18362..20419
                     /gene="pbp2b"
                     /locus_tag="VW883_000927"
     CDS             18362..20419
                     /gene="pbp2b"
                     /locus_tag="VW883_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0274091.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20430..21026
                     /gene="recR"
                     /locus_tag="VW883_000928"
     CDS             20430..21026
                     /gene="recR"
                     /locus_tag="VW883_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0274092.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21202..22245
                     /locus_tag="VW883_000929"
     CDS             21202..22245
                     /locus_tag="VW883_000929"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0274093.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLVYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            22329..23702
                     /locus_tag="VW883_000930"
     CDS             22329..23702
                     /locus_tag="VW883_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0274094.1"
                     /translation="MKLTIHEIAQVVGVKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLMP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23689..24300
                     /locus_tag="VW883_000931"
     CDS             23689..24300
                     /locus_tag="VW883_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0274095.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24391..25095
                     /locus_tag="VW883_000932"
     CDS             24391..25095
                     /locus_tag="VW883_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0274096.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25314..26687
                     /gene="ftsA"
                     /locus_tag="VW883_000933"
     CDS             25314..26687
                     /gene="ftsA"
                     /locus_tag="VW883_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0274097.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26704..27963
                     /gene="ftsZ"
                     /locus_tag="VW883_000934"
     CDS             26704..27963
                     /gene="ftsZ"
                     /locus_tag="VW883_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0274098.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27968..28639
                     /locus_tag="VW883_000935"
     CDS             27968..28639
                     /locus_tag="VW883_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0274099.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28649..29188
                     /locus_tag="VW883_000936"
     CDS             28649..29188
                     /locus_tag="VW883_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0274100.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29188..29451
                     /locus_tag="VW883_000937"
     CDS             29188..29451
                     /locus_tag="VW883_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0274101.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29448..30233
                     /locus_tag="VW883_000938"
     CDS             29448..30233
                     /locus_tag="VW883_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0274102.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30242..31030
                     /gene="divIVA"
                     /locus_tag="VW883_000939"
     CDS             30242..31030
                     /gene="divIVA"
                     /locus_tag="VW883_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0274103.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31378..34170
                     /locus_tag="VW883_000940"
     CDS             31378..34170
                     /locus_tag="VW883_000940"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0274104.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDWVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELIYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10576 a         6066 c         7465 g        10254 t
ORIGIN      
        1 aaactaattt agagaatgaa atatagagta tttctctctt aaaagttttt ggtgaaacga
       61 gatgtagaaa ggagatttag ccaaagagtc tattagtgct agaataatag attagaatta
      121 ttttagaaaa acgaagtgag cagcttataa attcaagtcc ccaaatagat tcatactagt
      181 atcttttgca aaaaataaag ggcgacttcc ttcatgaata tcaatttcat ctataaggaa
      241 ggtagctaat tgaactaact tatttattct gtttgtcgct agaaaaatca gacctccttg
      301 tgaagattga ggagatactt aatgaaaatc aaagaagaaa ctagcaagct agtagcagat
      361 tgcccaaaac accgctttga ggttgtagat aagactgacg tatataatcc aaggtgaagc
      421 gactgtggtt tgaagagatt ttcaaagagt ataggctaga gagtagtgtt tttatgtcct
      481 tctagtagaa aatgctagac agaagaatgg ggaacttgga taggaaaaat agattgagaa
      541 aggaggttag aagagatgat tattacaaaa attagccgtt taggaactta tgtgggagta
      601 aatccacatt ttgcaacatt aatagatttt ctagaaaaaa caggactaga aaatttaaca
      661 gaaggttcga ttgctatcga tggtaatcga ttgtttggga attgctttac ttatctagca
      721 gatggtcaag caggggcttt ctttgaaaca caccaaaaat atttggatat tcatttagtt
      781 ttggaaaacg aagaagccat ggctgttaca tcgccggaaa atgtaagcgt tacccaagaa
      841 tatgatgaag agaaagatat tgaattatac acagggaaag tggaacagtt ggttcatttg
      901 agagctggtg aatgcctcat cacttttcca gaagatttac atcaacccaa ggttcgtata
      961 aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga tttcttaatg tagaaagaga
     1021 agaacgatga aaaaaatgag aaagttttta tgtctagctg gaattgcgct agcggctgtt
     1081 gccttggtag cttgttcagg aaaaaaagaa gctacaacta gtactgaacc accaacagaa
     1141 ttatctggtg agattacaat gtggcactcc tttactcaag gaccccgttt agaaagtatt
     1201 caaaaatcag cagatgcttt catgcaaaag catccaaaaa cgaaaatcaa gattgaaaca
     1261 ttttcttgga atgacttcta tactaaatgg actacaggtt tagcaaatgg aaatgtgcca
     1321 gatatcagta cagctcttcc taaccaagta atggaaatgg tcaactcaga cgctttggtt
     1381 ccgctaaatg attctatcaa gcgtattgga caagataaat ttaacgaaac tgccttaaat
     1441 gaagcaaaaa tcggagatga ttactactct gttcctcttt attcacatgc acaagtcatg
     1501 tgggttagaa cagatttgtt aaaagaacat aatattgagg ttcctaaaac ttgggatcaa
     1561 ctctatgaag cttctaaaaa attgaaagaa gctggagttt atggcttgtc tgttccgttt
     1621 ggaacaaatg acttaatggc aacacgtttc ttgaacttct acgtacgtag tggtggagga
     1681 agcctcttaa caaaagatct taaagcagac ttgacaagcc aacttgctca agatggtatt
     1741 aaatactggg ttaaattgta taaagaaatc tcacctcaag attctttgaa ctttaatgtc
     1801 cttcaacaag ctaccttgtt ctatcaagga aaaacagcat ttgactttaa ctctggcttc
     1861 catatcggag gaattaatgc caacagtcct caattgattg attcgattga tgcttatcct
     1921 attccaaaaa tcaaagagtc tgataaagat caaggaattg aaacctcaaa cattccaatg
     1981 gttgtttgga aaaattcaaa acatccagaa gttgctaaag cattcttaga agcactttat
     2041 aatgaagaag actacgttaa attccttgat tcaactccag taggtatgtt gccaactatt
     2101 aaggggatta gcgattctgc agcctataaa gaaaatgaaa ctcgtaagaa atttaaacat
     2161 gctgaagaag taattactga agctgttaaa aaaggtactg ctattggtta tgaaaatgga
     2221 ccaagtgtac aagctggtat gttaactaac caacacatta ttgaacaaat gttccaagat
     2281 atcattacaa atggaacaga tcctatgaaa gcagcaaaag aagcagaaaa acaattaaat
     2341 gatttatttg aggctgttca gtagatgtaa aagactagaa aataggtggg ctagtgagct
     2401 gaaaagctct agcccaatct tgtaaaagaa gggagaagga gaatggttaa agaacgtaat
     2461 ttaactcgct ggatatttgt tttgccagct atgattatcg taggattact ctttgtttat
     2521 ccgtttttct cgagtatttt ttatagcttt accaataagc atttgattat gcctaattat
     2581 aaatttgttg gtttggctaa ctataaagct gtgctatcag atcccaactt ctttaatgcg
     2641 ttctttaatt caattaagtg gaccgttttc tcattagttg gtcaagtttt agtagggttt
     2701 gtattggctt tagctcttca cagagtacgc cacttcaaga aattatatag gaccttattg
     2761 attgttcctt gggcatttcc taccatcgtt attgcctttt cttggcagtg gattctaaac
     2821 ggggtttatg gctacttacc taatctaatc gtaaaattag gtttaatgga acatacacct
     2881 gcatttttga cagatagtac atgggcattc ctatgtttgg tgtttatcaa catttggttt
     2941 ggagcaccaa tgattatggt taatgtgctt tcagctttgc aaacagtacc agaagaacaa
     3001 tttgaggctg ctaagataga tggtgcttca agttggcagg tgttcaagtt tatcgtcttt
     3061 ccacatatta aagtggttgt aggacttcta gttgttttga gaactgtatg gatctttaat
     3121 aactttgaca ttatctacct cattactggt ggtggaccag ccaatgctac aacgacgctt
     3181 ccaatttttg cttacaacct gggttgggga actaaattgt tgggtcgtgc ttcagcagtt
     3241 acagtattgc tctttatctt cttggtggcg atttgcttta tctactttgc tatcatcagt
     3301 aagtgggaaa aggagggtag aaaataatga agaagaaatc cagtatttat ttagatattc
     3361 tctcacatgt acttttagtt ggtgcgacca tcgttgcaat tttcccattg gtatggatta
     3421 tcatatcttc tgtcaaaggg aaaggggaat taactcagta tccaacacga ttttggcctg
     3481 aacagtttac attagattat ttcactcatg ttatcaacga tttgcacttc attgataaca
     3541 ttcgaaacag tttaatcatt gccttggcta caaccctcat tgcgattatt atttctgcta
     3601 tggcagccta tggtattgtt cgattctttc ctaaattggg agcaatcatg tcgagactac
     3661 tcgtcattac ctacattttc ccaccaattt tgttagcaat tccctattca attgccattg
     3721 ctaaagttgg gttaacaaat agtttatttg gcttgatgat ggtttatcta tcttttagtg
     3781 ttccatatgc agtttggctc ttagttggat ttttccaaac agttccaatt ggaattgaag
     3841 aagcggctag aattgatggt gcaaataaat ttgttacgtt ttataaagtt gtgctaccga
     3901 ttgtagcacc aggtattgta gcaacagcta tttatacatt tatcaatgct tggaatgaat
     3961 tcctgtatgc cttgattttg attaacaata caggaaagat gacagtagca gtagcccttc
     4021 gttcacttaa tggttcagaa atactagact ggggagatat gatggcagcg tctgttattg
     4081 tagttcttcc atcaattatt ttcttctcta tcatccaaaa taagattgca agtggattat
     4141 cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg aataaaagag gtctttattc
     4201 aaaactagga atttctgttg taggcattag tcttttaatg ggagttccca ctttgattca
     4261 tgcgaatgaa ttaaactatg gtcaactgtc catatctcct atttttcaag gaggttcata
     4321 tcaactgaac aataagagta tagatatcag ctctttgtta ttagataaat tgtctggaga
     4381 gagtcagaca gtagtaatga aatttaaagc agataaacca aactctcttc aagctttgtt
     4441 tggcctatct aatagtaaag caggctttaa aaataattac ttttcaattt tcatgagaga
     4501 ttctggtgag ataggtgtag aaataagaga cgcccaaaag ggaataaatt atttattttc
     4561 tagaccagct tcattatggg gaaagcataa aggacaggca gttgaaaata cactagtatt
     4621 tgtatctgat tctaaagata aaacatacac aatgtatgtt aatggaatag aagtgttctc
     4681 tgaaacagtt gatacatttt tgccaatttc aaatataaat ggtatagata aggcaacact
     4741 aggagctgtt aatcgtgaag gcaaggaaca ttacctcgca aaaggaagta ttgatgaaat
     4801 cagtctattt aacaaagcaa ttagtgatca ggaagtttca aatattccct tgtcaaatcc
     4861 atttcagtta attttccaat caggagattc tactcaagct aactatttta gaataccgac
     4921 actatataca ttaagtagtg gaagagttct atcaagtatt gatgcacgtt atggtgggac
     4981 tcatgattct aaaagtaaga ttaatattgc cacttcttat agtgatgata atgggaaaac
     5041 gtggagtgag ccaatttttg ctatgaagtt taatgactat gaggagcagt tagtttactg
     5101 gccacgagat aataaattaa agaatagtca aattagtgga agtgcttcat tcatagattc
     5161 atccattgtt gaagataaaa aatctgggaa aacgatatta ctagctgatg ttatgcctgc
     5221 gggtattgga aataataatg caaataaagc cgactcaggt tttaaagaaa taaatggtca
     5281 ttattattta aaactaaaga agaatggaga taacgatttc cgttatacag ttagagaaaa
     5341 tggtgtcgtt tatgatgaaa caactaataa acctacaaat tatactataa atgataagta
     5401 tgaagttttg gagggaggaa agtctttaac agtcgaacaa tattcggttg attttgatag
     5461 tggctcttta agagaaaaac ataatggaaa acaggtccct atgaatgttt tctacaaaga
     5521 ttcgttattt aaagtgactc ctactaatta tatagcaatg acaactagtc agaatagagg
     5581 agagagttgg gaacaattta agttgttgcc tccgttctta ggagaaaaac ataatggaac
     5641 ttacttatgt cccggacaag gtttagcatt aaaatcaagt aacagattga tttttgcaac
     5701 atatactagt ggagaactaa cctatctcat ttctgatgat agtggtcaaa catggaagaa
     5761 atcctcagct tcaattccgt ttaaaaatgc aacagcagaa gcacaaatgg ttgaactgag
     5821 agatggtgtg attagaacat tctttagaac cactacaggt aagatagctt atatgactag
     5881 tagagattct ggagaaacat ggtcgaaagt ttcgtatatt gatggaatcc aacaaacttc
     5941 atatggcaca caagtatctg caattaaata ctctcaatta attgatggaa aagaagcagt
     6001 cattttgagt acaccaaatt ctagaagtgg ccgtaaggga ggtcaattag ttgtcggttt
     6061 agtcaataaa gaagatgata gtattgattg gaaataccac tatgatattg atttgccttc
     6121 gtatggttat gcctattctg cgattacaga attgccaaat catcacatag gtgtactgtt
     6181 tgaaaaatat gattcgtggt cgagaaatga attgcattta agcaatgtag ttcagtatat
     6241 agatttggaa attaatgatt taacaaaata aaggagaaaa acatggttaa atacggtgtt
     6301 gttggagcag ggtattttgg agctgaattg gctcgctaca tgcaaaagaa tgatggagca
     6361 gagattactc ttctctatga tccagataat gcagaggcga ttgcagaaga attgggagca
     6421 aaagtagcaa gttccttaga tgagttggtt tctagcgatg aagtagattg tgttatcgtc
     6481 gcaactccaa ataatcttca taaggaaccg gttattaagg ctgcacagca tggtaaaaat
     6541 gttttctgtg aaaaaccaat tgcgctttct tatcaagatt gtcgcgagat ggtagatgcg
     6601 tgtaaagaaa acaatgtaac ctttatggca ggacatatta tgaatttctt taatggtgtt
     6661 catcatgcaa aagaactcat taatcaagga gttatcggag acgttctata ttgtcataca
     6721 gctcgtaatg gttgggaaga acaacaaccg tcagtatcat ggaaaaaaat tcgtgaaaaa
     6781 tcaggtggtc acttgtatca ccacatccat gaattggatt gcgttcaatt ccttatgggg
     6841 ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg cccatgaagg tgaacatttc
     6901 ggtgatgaag atgatatgat ttttgtcaat atggaatttt ctaataagcg ttttgctttg
     6961 ttagaatggg gttcagctta tcgttggggt gaacattatg tcttaatcca aggaagcaaa
     7021 ggtgccatcc gcttagactt attcaactgt aaaggaactc ttaagctaga tgggcaagaa
     7081 agctatttct tgattcacga atcgcaagaa gaagatgatg atcggactcg tatctatcat
     7141 agtacagaga tggatggagc aattgcttat ggtaaaccag gtaaacgtac tccattatgg
     7201 ctatcatctg tcattgataa agaaatgcgc tatctgcatg agattatgga aggagctcca
     7261 gtatcagaag aatttgcaaa acttttgaca ggtgaagctg ccctagaagc aattgctact
     7321 gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag taaaattgtc agaaattgta
     7381 aaataaattt tggtattctc ctatttatag gtcgacttgc tcctctgaaa gtacttttag
     7441 aggagctgtt tgactttgct agtttttgaa actgaaatct attatactac aaactattga
     7501 aagcgtttta attttaaggt ataataatct catagaaata aagaaaagga ggaaagagga
     7561 tgccacagat tagcaaagaa gccttgattg agcaaatcaa agatggaatc atcgtttctt
     7621 gtcaggctct tcctcatgaa ccgctttata cagaagcggg aggggtgatt cccttgctgg
     7681 tcaaagcggc tgagcaaggt ggagcagtcg gtatccgagc aaacagtgtt cgcgatatca
     7741 aggaaattaa ggaagtcact aaacttccaa tcattgggat tatcaaacgt gattatccac
     7801 ctcaggaacc cttcatcacg gctactatga aagaagttga tgaattggca gaactggaca
     7861 tcgaggtgat tgctctggat tgtaccaagc gtgaacgcta cgatggtttg gaaattcaag
     7921 agttcattcg tcaggttaag gagaaatatc ctaatcagct tttgatggct gatactagta
     7981 tcttcgaaga agggctagca gctgtagaag caggaattga ctttgtcgga acaaccttat
     8041 caggctacac atcctacagt ccaaaagtag acggtccaga ttttgaattg attaagaaac
     8101 tctgtgatgc cggtgtagat gtcattgcag aaggaaaaat tcatacacca gaacaagcca
     8161 aacaaatcct tgaatatgga gtgcgaggca tcgttgttgg tggcgccatt actagaccaa
     8221 aagagattac agaacgcttc gttgctagtc ttaaataaga tgtgaggggg agttttatgt
     8281 ttaaagtttt acaaaaagtt ggaaaagctt ttatgttacc tatagctata cttcctgcag
     8341 caggtctact tttggggatt ggtggtgcac tttcaaaccc aaccacgata gcaacttatc
     8401 caatactaga caatagtatt tttcaatcaa tattccaagt aatgagctct gcaggagagg
     8461 ttgtattcag taatttgtca ctacttctct gtgtgggatt atgtattggc ttagcgaaac
     8521 gagataaagg aaccgctgcg ttagcaggag taactggtta cttagttatg actgcaacga
     8581 tcaaagcttt agtaaaactt tttatggcag aaggatctgc aattgatact ggagttattg
     8641 gagcattagt tgtcggaata gttgccgtat atttgcacaa ccgatataac aatattcaat
     8701 taccttccgc tttaggattc tttggaggtt cacgcttcgt tcctattgtt acatcgttct
     8761 cttctatctt gattggcttt gtcttctttg ttatttggcc acctttccaa caacttcttg
     8821 tttctacagg tggatatatt tctcaggcgg gtccaattgg aacttttcta tatggatttt
     8881 taatgagact ttctggagca gtaggcttac atcatataat ttaccctatg ttttggtata
     8941 ctgaacttgg tggtgttgaa actgttgcag gacaaacagt ggttggagct caaaaaatat
     9001 tttttgctca attagccgat ttggcccatt ctggattatt tacagaagga acaaggtttt
     9061 ttgcaggtcg tttctcaaca atgatgttcg gtttaccggc tgcctgttta gcgatgtacc
     9121 atagtgttcc taaaaatcgt cgtaaaaaat acgcgggttt gtttttggga gttgctttaa
     9181 catcttttat taccggtatt acagaaccaa ttgaatttat gtttctattc gtcagtccgg
     9241 ttctatatgt tgttcacgca ttccttgatg gtgttagctt ctttattgca gacgtcttaa
     9301 atatttcaat aggaaacaca ttttcaggag gtgtaatcga tttcacatta tttggaattt
     9361 tgcaggggaa cgctaagacg aattgggttc ttcagattcc atttggactt atttggagtg
     9421 ttttgtatta tattattttt agatggttca ttactcaatt caacgttcta acgccaggac
     9481 gaggagaaga agtagattct aaagaaattt ctgaatccgc agattcgact tcaaatactg
     9541 cagattattt aaaacaggat agcctacaaa ttatcagagc cttgggtgga tcaaataata
     9601 tagaagatgt agatgcttgt gtgacacgtt tacgtgtagc tgtaaaagaa gttaatcaag
     9661 ttgataaagc acttttaaaa caaattggtg cagttgatgt cttagaagtg aagggtggca
     9721 ttcaagcaat ctatggagca aaagcaatct tatataaaaa tagtattaat gaaattttag
     9781 gtgtagatga ttaagtactt actgacttaa taaaaaacag aggagagtga tggatgagta
     9841 ggatgaaatg aaatcgcata caagaaataa agaactcatt atccaagttg gatacgctta
     9901 ttacatagga gaatacaaat gaaatttaga aaattagctt gtacagtact tgcgggtgct
     9961 gcggttcttg gtcttgctgc ttgtggcaat tctggcggaa gtaaagatgc tgccaaatca
    10021 ggtggtgacg gtgccaaaac agaaatcact tggtgggcat tcccagtatt tacccaagaa
    10081 aaaactggtg acggtgttgg aacttatgaa aaatcaatca tcgaagcgtt tgaaaaagca
    10141 aacccagata taaaagtgaa attggaaacc atcgacttca agtcaggtcc tgaaaaaatc
    10201 acaacagcca tcgaagcagg aacagctcca gacgtactct ttgatgcacc aggacgtatc
    10261 atccaatacg gtaaaaacgg taaattggct gagttgaacg acctcttcac agatgaattt
    10321 gttaaagatg tcaacaatga aaacatcgta caagcaagta aagctggaga caaggcttat
    10381 atgtatccga ttagttctgc cccattctac atggcaatga acaagaaaat gttagaagat
    10441 gctggagtag caaaccttgt aaaagaaggt tggacaactg atgattttga aaaagtattg
    10501 aaagcactta aagacaaggg ttacacacca ggttcattgt tcagttctgg tcaaggggga
    10561 gaccaaggaa cacgtgcctt tatctctaac ctttatagcg gttctgtaac agatgaaaaa
    10621 gttagcaaat atacaactga tgatcctaaa ttcgtcaaag gtcttgaaaa agcaactagc
    10681 tggattaaag acaatttgat caataatggt tcacaatttg acggtggggc agatatccaa
    10741 aactttgcca acggtcaaac atcttacaca atcctttggg caccagctca aaatggtatc
    10801 caagctaaac ttttagaagc aagtaaggta gaagtggtag aagtgccatt cccatcagac
    10861 gaaggtaagc cagctcttga ataccttgta aacgggtttg cagtattcaa caataaagac
    10921 gacaagaaag tcgctgcatc taagaaattc atccagttta tcgcagatga caaggagtgg
    10981 ggacctaaag acgtagttcg tacaggtgct ttcccagtcc gtacttcatt tggaaaactt
    11041 tatgaagaca aacgcatgga aacaatcagc ggctggactc aatactactc accatactac
    11101 aacactattg atggatttgc tgaaatgaga acactttggt tcccaatgtt gcaatctgta
    11161 tcaaatggtg acgaaaaacc agcagatgct ttgaaagcct tcactgaaaa agcaaacgaa
    11221 acaatcaaaa aagctatgaa acaatagtcc ttagttattc tataaaaagt agttttttaa
    11281 agaacctaag agtgtatacc cccttttccc tctacacaga tagtgtaaga aaagggggct
    11341 tttgtttaaa atgtaagaaa ctgtcacgaa attaaaatga agttcttaca taagcgaatc
    11401 ataaaaaatt tcattttgat tttaaaacag ttcaagaaag tcaaaaaatt attctatttg
    11461 aaagagaggt gccgactgtg aaagtcaata aaatccgtat gcgggaaaca gtgatttcct
    11521 acgctttcct agcaccagta ttattcttct ttgtcatctt tgtgttggct ccgatggtga
    11581 tgggcttcat tacaagtttc tttaactact caatgactaa atttgagttt gtaggcttgg
    11641 ataactatat ccgtatgttt aaagatcctg tctttacaaa atctctgatt aacacagtta
    11701 ttttggttat tggatctgta ccagttgttg ttctattctc actctttgta gcatctcaga
    11761 cctatcatca aaatgtcatt gccagatcct tctaccgttt cgtcttcttc cttcctgttg
    11821 taacgggtag tgttgccgtg acagttgttt ggaaatggat ttatgaccca ctatcaggga
    11881 ttctaaactt tgtccttaag tcaagccaca tcatcagcca aaacatttct tggttgggag
    11941 ataaaaactg ggcattgatg gcgattatga ttattctctt gaccacttca gttggtcagc
    12001 ccatcatcct ttatatcgct gccatgggga atattgacaa ttcactggtt gaagcggcgc
    12061 gtgttgatgg tgcaactgag tttcaagttt tttggaagat taaatggcca agccttcttc
    12121 caacaactct ttatattgca atcatcacaa caattaactc attccagtgt ttcgccttga
    12181 ttcagctttt gacatctggt ggtccaaact actcaacaag taccttgatg tactaccttt
    12241 acgaaaaagc cttccaattg acagaatacg gctatgccaa cacaattggt gtcttcttgg
    12301 cagtcatgat tgctatcgta agctttgttc aatttaaagt acttggaaac gacgtagaat
    12361 actaaagaaa ggagacagct atgcaatcta cagaaaaaaa accattaaca gcctttactg
    12421 ttatttcaac aatcattttg ctcttgttga ctgtgctgtt catctttcca ttctactgga
    12481 ttttgacagg ggcattcaaa tcacaacctg atacaattgt tattcctcct cagtggttcc
    12541 ctaaaatgcc aaccatggaa aacttccaac aactcatggt gcagaaccct gccttgcaat
    12601 ggatgtggaa ctcagtattt atctcattgg taaccatgtt cttagtttgt gcaacctcat
    12661 ctctagcagg ttatgtattg gctaaaaaac gtttctatgg tcaacgcatt ctatttgcta
    12721 tctttatcgc tgctatggcg cttccaaaac aagttgtcct tgtaccattg gtacgtatcg
    12781 tcaacttcat gggaatccat gatactctct gggcagttat cttgcctttg attggatggc
    12841 cattcggtgt cttcctcatg aaacagttca gtgaaaatat ccctacagag ttgcttgaat
    12901 cagctaaaat cgacggttgt ggtgagattc gtaccttctg gagtgtagcc ttcccgattg
    12961 tgaaaccagg gtttgcagcc cttgcaatct ttaccttcat caatacttgg aatgactact
    13021 tcatgcaatt ggtaatgttg acttcacgta acaatttgac catctcactt ggggttgcga
    13081 ccatgcaggc tgaaatggca accaactatg gtttgattat ggcaggagct gcccttgctg
    13141 ctgttccaat cgtcacagtc ttcctagtct tccaaaaatc cttcacacag ggtattacta
    13201 tgggagcggt caaaggataa tactctgcga aaatcgaatg caaactacgt cagcttcacc
    13261 ttgccatact taagtattgc ctgcggttag cttcctagtt tgttcttcaa ttttcattga
    13321 gtataggaaa atcaatctat caagatacag aagtatattt tatagattta gagaatatag
    13381 aggttataag tgtctacaaa atggagggta tgcagttact ttatgaagtt ttgtcagaca
    13441 cttatcaact taagaatggt tttagttaac tatcagaaac gaaggaaaga gtatgatttt
    13501 tgacgatttg aaaaacatca ccttttacaa agggattcat cccaatttag acaaggctat
    13561 cgactacctc taccaacatc gtaaagattc attcgaatta ggaaagtatg agattgatgg
    13621 agataaagtc tttctagttg ttcaggaaaa tgtcctcaat caagttgaga ataatcaatt
    13681 tgaacaccat aagaactatg cagatttgca tttgctgata gaagggcatg aatattcgag
    13741 ctacggttca cgtatcaaag acgaggcagt agcattcgac gaagcgagtg acattggctt
    13801 tgttcattgt catgaacact acccactctt attgggttat cacaattttg cgattttctt
    13861 cccaggtgag ccacatcagc caaatggtta tgcaggcatg gaagaaaagg ttcgaaaata
    13921 tctctttaaa attttgattg attaaaaata ggatgaattg tttttttgta aagctttgac
    13981 aatactctac catgaaattg atctttgtga ggtagagaaa tgagaataaa atatttaaaa
    14041 attggtatct tctaagtatg ctgcaagagc cagtttctta gatggacagg ggattacagt
    14101 tgatgagatg tcctggataa ttaatggcat tgtgaatgga ttgattggta gatacataaa
    14161 attaggtatt tatgcagcca agtatggtat tagtatggtg cgatcgatct taagtagggc
    14221 agctgcaact gcggcagcaa gagtaggatt attgaccaag atttttggat ggattttacg
    14281 aatagctgtg ctcgcagctg atgtatatgg taattttgcc aacaatattg ctgcagcttg
    14341 ggatgcatat gataaaattc ctaacaatgg tcgtataaac ttttaaaatg cgagaatgaa
    14401 agcactttgt atttttttat tgaatatgtt agcttggaca gtgcttgcaa tgataattcg
    14461 tggagggcta gatggatttg ataggcatac ttggagtact attttaattg cttcgctgtc
    14521 cgggatatat gattataagc ccatagataa aaatagaaaa aagtccaaaa gaaaaaatag
    14581 atttgttcat ggtagggact tatgaaagct ttactgacaa aaaagaaaac agtttacaaa
    14641 gaaaaatgat ggaggagcaa acatggcaca aaaaggagta agccttatca aggcagcatt
    14701 tgatacagat aactttctca tgcgttttag tgagaaggtc ttggacatcg tgacagccaa
    14761 tcttcttttt gtcgtctctt gtttacccat cgtgacgatt ggagtggcta aaatcagcct
    14821 ctacgagacc atgttcgaag ttaagaagag cagacgggtg cctgttttta aaatctatct
    14881 aagatctttc aagcaaaatc tgaaactagg tcttcagctg ggtttaatgg agttaggaat
    14941 tgtgtttctt accctttcag atctctatct tttctggggt caaacagctc tgcccttcca
    15001 attgctgaaa gccatttgtt taggtattct gatttttctt actatcgtga tgctggctag
    15061 ttaccctatc gcggcacgtt atgacctatc ttggaaagaa attcttcaaa aaggattgat
    15121 gttggctagt tttaactttc cttggttctt cctcatgtta gccattcttg tcctcattgt
    15181 gatggttctt tatctgtccg ccttcagtct actcttaggt ggctcagcct tcctactttt
    15241 tgggtttgga ctattggtct ttatccagac tggattgatg gagaaaattt tcgcaaaata
    15301 ccaataggag ctttatttct gaaactactt tcaaaggctc caaacgctat tctataagcg
    15361 agaaactaaa atctaagtgt ctataagata ttgaaagcct tttcggtaaa gtgtatacta
    15421 aagaagtaaa gaaaaatctg ctttagcaga aaataaaaat aataggagaa aatctatgtc
    15481 agatttgaaa aaatacgaag gtgtcattcc agccttctac gcatgttatg atgatcaagg
    15541 agaagtaagc ccagaacgta cgcgtgcctt ggttcaatac ttcattgata aaggtgttca
    15601 aggtctttat gtcaatggtt cttctggtga atgtatctac caaagcgttg aagatcgcaa
    15661 gttgattttg gaagaagtca tggcggtagc taaaggtaaa ttgaccatta ttgcccatgt
    15721 tgcctgcaac aatactaaag acagtatgga acttgctcgc catgctgaaa gcttgggagt
    15781 agatgctatt gcaacgattc caccaattta tttccgcttg ccagaatact cagttgccaa
    15841 atactggaac gatatcagtt ctgcagctcc aaacacagac tacgtgattt acaacattcc
    15901 tcaattggca ggggttgctt tgactccaag cctttacaca gaaatgttga aaaatcctcg
    15961 tgttatcggt gtgaagaact cttctatgcc agttcaagat atccaaacct ttgtgagcct
    16021 tggtggggaa gaccatatcg tctttaacgg tccagatgaa cagttcctag gtggtcgcct
    16081 catgggtgcc aaagctggta tcggtggtac ttatggtgct atgccagaac tcttcttgaa
    16141 actcaaccaa ttgattgcgg ataaagattt agaaacagcg cgtgagttac agtatgctat
    16201 caacgctatc attggtaaat tgactgctac acatggaaat atgtacggtg tcatcaaaga
    16261 agttttgaag atcaatgaag gcttgaatat tggttctgtt cgttcaccat tgacaccagt
    16321 gactgaagaa gatcgtccag ttgtagaagc ggctgctgcc ttgattcgtg aaaccaagga
    16381 gagcttcctc taatctaaaa ggaggtattt atgacatact acgttgcaat tgatatcggt
    16441 ggaaccaaca tcaagtatgg tttggttgat caagaggggc aacttcttga atcgcatgaa
    16501 atgccaactg aggcgcataa gggtggacct catatcttac aaaagaccaa agatatcgta
    16561 gctagttatt tagaaaaagg cccagtagca ggtgttgcca tatcttctgc tgggatggtg
    16621 gatccggata agggtgagat tttctatgct gggccgcaaa tccctaacta cgcaggcacc
    16681 cagttcaaaa aggaaatcga agaaagcttt actattcctt gtgagattga aaatgatgtc
    16741 aactgtgcag gtcttgctga ggcagtatct ggttcaggca agggagcaag tgtgacactt
    16801 tgcttgacca ttggaacagg tatcggtggt tgcttgatta tggataggaa agtcttccat
    16861 ggttttagca attcagcctg tgaagtcggg tatatgcata tgcaggatgg agcttttcaa
    16921 gacttggctt ctacaacagc tttagtgaaa tatgtagctg aagcccatgg agaagatgtt
    16981 gatcagtgga atggccgacg tatctttaag gaagccactg aaggaaacaa aatctgcatg
    17041 gaaggtattg accgtatggt tgactatcta ggaaaaggtc tggcaaatat ttgctacgtt
    17101 gccaatccag aagtggttat tcttggtggt ggtatcatgg ggcaagaggc tatcctcaaa
    17161 cctaagatcc gcacagcctt gaaagaggct ttggtaccaa gtttagcaga aaaaacacga
    17221 ttagaatttg cccatcacca aaatacagca gggatgttgg gtgcatatta tcattttaag
    17281 acaaaacaat cctagtttgg ctcagccaaa ctaggatttt cttacacgtt tttgtctacg
    17341 atagccgttg agttttttat tttcccagta gctattaaag attttttcct tgctttcgcg
    17401 attgatttcc aaaaagtagg cataaatcaa atcgataaag aagagcatag gaagttgagc
    17461 ggatattcgt tggatatagg agggttggct gtgggtggct acaagaacag tctctgtata
    17521 ggtctggcta tctttattgg gaacacttgt aaagagtaca gtctttgccc ccatctcctt
    17581 ggcatctaat agactatcta aaatagaagg agttgagcct gaaagtgaga agcccagtac
    17641 tagacaattt tcatccatga tgctggttgt ccaggcaaag ccgtcttggt ctgtcaaagc
    17701 ttcgcagacc acacctagtc gcataaaacg taatttcatt tcacgggcga cgaggccaga
    17761 actccctgtt ccaaagaagt agatacgctc agcatcttcg attagctggg caattcgctc
    17821 tagttggatt tcgtcaatca agtcttgtgt ttgttccctc atattgctat aacttctgag
    17881 gactcgtttg gtcagtggac tgtgcttgga gacttggttg gcttgatttt ctgcctgatg
    17941 ttggtattgg aaaataaatt ctcggtagcc agtaaagcca cactttttag caaagcgggt
    18001 caaagcagct tgagaaatat gtaatttttg ggtgacttgt tgagaagata aatcatctgt
    18061 aatcgtttca gcttgcaaaa aatagcgagc gatttcttgc tctaggtctg tcatttcttc
    18121 aaaatgtgaa tcaatgatag ttgcgatatc tggtttgtcc atagggaaag ctcctttaca
    18181 tgagtcatac tggaagacta gatcagggaa tagtcacact tcattataac acataatata
    18241 aggatatata aacaaaaacg catctctgtt ttaaaaacga aaaaatcgaa aaagcttctc
    18301 tcttttccat aattttctac tcaaattgtg gtacaattaa gagtaagatt ttaagttaga
    18361 aatgagactg atttgtatga gaaaatttaa cagccattcg attccgattc ggcttaattt
    18421 attgttttca atcgtcattt tactctttat gaccattatt ggtcgtttgt tgtatatgca
    18481 ggttttgaac aaggattttt acgaaaaaaa gctagcctca gctagtcaga ccaagattac
    18541 aagcagttca gcccgtgggg aaatttatga tgctagtgga aaacctttgg tagaaaatac
    18601 gttaaagcag gttgtttcct ttacgcgtag caataaaatg acggctacag acttaaaaga
    18661 aacagctaaa aagttactga cttatgtgag catcagttct ccaaatttga caaaacgcca
    18721 gctggcggat tactatttgg ctgatcctga aatctataaa aaaacagtgg aagctctccc
    18781 aagcgagaaa cgcttggatt cagatggcaa tcgtctatcc gaatcagaac tgtataacaa
    18841 tgcggtcgat agtgtccaaa caagtcaact aaactataca gaggatgaaa agaaagaaat
    18901 ctatcttttt agtcagttaa atgctgttgg aaactttgcg acaggaacca ttgctacaga
    18961 tcctctaaat gattctcagg tggctgttat tgcctctatt tcaaaggaga tgcctggcat
    19021 tagtatttct acttcttggg atagaaaggt tttggaaact tccctttctt ctatagttgg
    19081 gagtgtatcc agtgaaaaag ctggtctccc agcggaagaa gcagaagcct atcttaaaaa
    19141 aggctattct ctaaatgacc gtgtaggaac ctcctatttg gaaaagcaat atgaagagac
    19201 cttacaagga aaacgctcgg taaaagaaat ccatctggat aaatatggca atatggaaag
    19261 cgtggataca attgaggaag gtagtaaggg aaacaatatc aaactgacca ttgatttggc
    19321 cttccaagat agcgtggatg ctttgctgaa aagttatttc aattctgagc tagaaaatgg
    19381 tggagccaag tattctgaag gtgtctatgc agtcgccctt aacccaaaaa caggtgcggt
    19441 tttgtctatg tcagggatta aacatgactt gaaaacggga gagttgacgc ctgattcctt
    19501 gggaacggta accaatgtct ttgttccagg ttcggttgtc aaggcggcga ccatcagctc
    19561 aggttgggaa aatggagtct tgtcaggaaa ccagaccttg acagaccagt ccattgtctt
    19621 ccaaggttca gctcccatca attcttggta tactcaggct tacggttcat tccctatcac
    19681 agcggtccaa gctctggagt attcatctaa tacctatatg gtccaaacag ccttaggtct
    19741 tatggggcaa acctatcaac ccaatatgtt tgtcggcacc agcaatctag agtctgctat
    19801 ggagaaactg cgttcaacct ttggcgaata tggcttgggt actgcgacag gaattgacct
    19861 accagatgaa tctactggat ttgttcccaa agagtatagc tttgctaatt acattactaa
    19921 tgcctttggg cagtttgata actatacgcc gatgcagttg gctcagtatg tagcaactat
    19981 tgcaaataat ggtgttcgtg tggctcctcg tattgttgaa ggcatttatg gtaataatga
    20041 taagggagga ctgggtgact tgattcagca actgcaaccg acagagatga ataaggtcaa
    20101 tatatccgac tccgatatga gcatcttgca ccaaggtttt tatcaggttg cccatggtac
    20161 tagtggattg acaactggac gtgccttttc aaatggtgcc ttggtatcca ttagcggaaa
    20221 aacaggtaca gccgaaagct atgtggcaga tggtcagcaa gcaaccaata ccaatgcggt
    20281 ggcctatgcc ccatctgata atccccaaat cgctgtcgca gtggtctttc ctcataatac
    20341 caatctaaca aatggtgtag gaccttccat tgcgcgtgac attatcaatc tgtatcaaaa
    20401 ataccatcca atgaactaga aaggaaatta tgctttatcc aacacctatt gccaagttga
    20461 ttgacagtta ttctaagtta ccaggtatcg ggattaagac ggctacgcgt ctggcctttt
    20521 atacgattgg gatgtctgct gatgatgtca atgaatttgc aaaaaatctc ctttctgcta
    20581 agagagaatt gacatattgt tctatttgtg gacgtttgac agacgacgat ccttgttcta
    20641 tctgtactga tccgactcgt gaccagacaa caattttagt tcttgaggat agtagagatg
    20701 tggcagccat ggaaaatatc caagaatacc atggactcta tcatgtcctt catggcctca
    20761 tttctcctat gaatggtatc agtccggacg atatcaatct caagagcctt atgactcgtc
    20821 ttatggatag tgaggtttca gaagtgattg tggcgactaa tgctacagcg gatggtgaag
    20881 cgacttccat gtatctttca cgtttgctca agccggctgg tatcaaggtt acgcgtctag
    20941 cacgaggtct cgctgtggga gcggacattg agtatgcgga cgaagtgaca ctcttacgag
    21001 ccattgaaaa tcggacagag ttgtaagtgt aggcaaattt acgaactcca ttcatttata
    21061 aaaaatcaaa gaggctgaaa atcgttccta tcggcctctt tttgtatagt gtgatgagta
    21121 ggctcaggtt caagttttaa aaaaccaagc aaatatgata tactaaagag cgagtattct
    21181 agtagaatta ggacaaataa tatgaaacaa acgattattc ttttatatgg tggacggagt
    21241 gcggaacgcg aagtctctgt cctttcagct gagagtgtca tgcgtgcggt caattacgac
    21301 cgtttcacag tcaagacttt ctttatcagt cagtcaggtg actttatcaa aacgcaggaa
    21361 tttagtcatg ctccggggca agaagaccgt ctcatgacca atgaaaccat tgattgggat
    21421 aagaaagttg caccaagtgc tatctacgaa gaaggtgcag tggtctttcc agtccttcac
    21481 gggccaatgg gagaagatgg ctctgttcaa ggattcttgg aagttttgaa aatgccttac
    21541 gttggttgca acattttgtc atcaagtctt gccatggata aaatcacgac taagcgtgtt
    21601 ctggaatctg ctggtattgc ccaagttcct tatgtggcta tcgttgaagg cgatgatgtg
    21661 actgctaaaa tcgctgaagt ggaagaaaaa ttggtttatc cagtcttcac taagccgtca
    21721 aacatggggt ctagtgtcgg tatttctaag tctgaaaacc aagaagaact ccgtcaagcc
    21781 ttaaaacttg ccttccgata tgacagccgt gtcttggttg agcaaggagt gaatgcccgt
    21841 gaaattgagg ttggcctctt gggtaactac gatgtcaaga gcacgctacc aggagaagtt
    21901 gtcaaggacg ttgcctttta tgactacgat gccaagtata ttgataacaa gattactatg
    21961 gatattcctg ccaaaatcag tgatgatgtg gtggctgtca tgcgtcaaaa tgcagaaaca
    22021 gccttccgtg ccattggtgg ccttggtcta tctcgttgcg atttcttcta tacagataag
    22081 ggagagattt ttctcaacga gctcaatacc atgccaggtt tcacccagtg gtctatgtac
    22141 ccactacttt gggacaatat ggggatcagc tacccaaaac taatcgagcg tttggttgac
    22201 cttgccaagg aaagttttga caagcgcgaa gcgcatttga tataaaatga aagagagggt
    22261 agaagccaga accatcactg caaggtgact agagttctcg gacttcagcc ctttttaaag
    22321 gagtagaaat gaaattaaca atccatgaaa ttgcccaagt tgttggagtc aaaaatgata
    22381 tcagtatctt tgaggacacc cagttagaaa aagctgagtt tgatagtcgt ttgattggaa
    22441 ctggagattt atttgtgcca cttaaaggtg cgcgtgatgg ccatgacttt attgaaacag
    22501 cctttgaaaa tggtgcagca gtaaccttgt ctgagaaaga ggtctcaaat catccttaca
    22561 ttctagtaga tgatgttttg acagcctttc aatccctagc atcctactat cttgaaaaaa
    22621 cgactgttga tgtctttgct gttacaggtt caaatggcaa gacaacgact aaggatatgt
    22681 tggcgcattt actgtcaaca agatacaaga cctacaaaac acaaggcaat tacaataatg
    22741 agattggcct tccttacaca gttcttcata tgcctgaagg aacagaaaag ttggttttgg
    22801 agatgggaca ggatcacttg ggagatattc atctcttgtc tgaattggct cgtccaaaaa
    22861 cagccatcgt gaccttggtt ggagaagctc atttggcctt tttcaaagat cgttctgaga
    22921 ttgctaaagg aaaaatgcaa attgcagacg gaatggcttc aggttccttg cttttaatgc
    22981 cggctgaccc tatcgtagag gactatttgc caactgataa aaaggtggtc cgttttgggc
    23041 aaggggcaga gttggaaatc acagacttgg ttgagcgtaa ggacagtctg acctttaagg
    23101 ctaatttctt ggaacaagcc cttgatttgc cagtgactgg taagtacaat gctaccaatg
    23161 ctatgattgc atcctatgtt gccctacaag aaggagtttc agaggagcaa attcatcagg
    23221 ccttccaagg tcttgaattg acgcgtaatc gtactgagtg gaagaaagca gccaatggag
    23281 cagatatcct gtcagacgta tataatgcca atccaactgc tatgaagctg attttagaga
    23341 ctttctctgc cattccagcc aatgaaggtg gcaagaaaat tgcagtgttg gcggatatga
    23401 aggagcttgg tgaccagtct attcaactcc ataaccagat gattttgagc ctttctccag
    23461 atgtgcttga taccgttatt ttctatggag aagacattgc tgaattagcc caattggcca
    23521 gtcaaatgtt cccaattggc cacgtttact acttcaagaa aacagaagac caagaccaat
    23581 ttgaagacct agtcaagcag gtcaaagaaa gccttggggc tcatgaccaa atcctgctca
    23641 aaggctctaa ctctatgaat ctagccaagt tggtagaaag tttagaaaat gaagacaagt
    23701 gattttgtca agtatttgca aagaatgatt gccattacag atactggctt aacctttaca
    23761 aaagatccgt ttgaccgtga gcgctacgaa gacttgcgag accttttatc tgaaatgttg
    23821 aatcaagcat cagaccttga ttccgaagaa gtggcagaag tcttgaagcc aacttctgct
    23881 tatgcgactc cgttaatgga cgtccgtgct tggattgttg aggacgaaaa gatttgtctg
    23941 gttaggggac aaggagagga tagttgggct ttgccaggtg gctttggtga agtcggctat
    24001 tctccaactg aaaatattct caaggaaatt gaagaagaaa ccggttttaa agccaaagtt
    24061 gaaagactgc tagctgtttt tgataccaat cgtttccaac tacagagcaa acaatatgca
    24121 aagtttgttt ttgaatgtaa gcttctcgat ggacaattcc aagaaaatca agaaatcgct
    24181 gaccttcaat tttttgcaat tgaccaactg ccgaatttat ctgaaaaacg cattaccaag
    24241 gagcaaatcg agattctttg gcaggtttat caaggtcaga gggagcaata tcttgactaa
    24301 gaagatgatt atcgtatttc taaattcatt tttcttaagt agcatggtat aataaaatgc
    24361 aggaaaattt tgaatcatga ggaagactag atgaatttat gggatatttt ctttacgact
    24421 caggcaaccg agccgcccaa atttgacctt ttttggtatg ttagcctatt tacgctctta
    24481 gccttaacct tttatacagc ccatcgctat cgtgaaaaga aggtttacca acgatttttc
    24541 caaatcttgc agactgttca gttaatcctt ctttatggtt ggtactgggt caatcatatg
    24601 ccactgtcag aaagcctacc cttttaccat tgccgtatgg ctatgtttgt ggtactcttg
    24661 cttcctggtc agtccaaata taaacaatac tttgcattat tgggaacatt tgggacatta
    24721 gcagcctttg tttatccagt gccagatgct tacccttttc cacatatcac cattctatcc
    24781 tttatctttg gtcatttagc actcttgggg aactctctag tttatctatt gagacagtat
    24841 aatgcgcgat tgctggatgt gaagggaatt tttctcatga cctttgccct aaatgccttg
    24901 atttttgtgg tcaatttggt gacaggtggc gattacggat ttttgacaaa accgccattg
    24961 gttggggatc acggtctagt agctaattat ttacttgttt caattgtgct ggtagctact
    25021 atcagtttga ctaagaaaat cttagaattc tttttagctc aagaagcaga aaaaatgatt
    25081 gcaaaggaag cttaacacag agctttcttt tttgctctta gagagttttt acaagcagct
    25141 tataaaataa gaatttctga atagacaaac tcaaaaaatg gctgggaaat ttaggaaaaa
    25201 agcaagcacg attaaatttt ttgtgttata atattttgtg aatagctatg cctatgttta
    25261 gctatggaat aatacgaagt gcgaaacttg gaagatagag aggaagcgat gtaatggcta
    25321 gagaaggctt ttttacaggt ctagatattg gaacaagctc tgtcaaggtg cttgtggccg
    25381 agcagagaaa tggtgaatta aatgtaattg gcgtgagtaa tgccaaaagt aaaggtgtaa
    25441 aggatggaat tattgttgat attgatgcag cagcaactgc tatcaagtca gccatttccc
    25501 aagcggaaga aaaggcaggc atttcgatta aatcagtgaa tgtcggcttg cctggtaatc
    25561 ttttgcaggt agaaccaact caggggatga ttccagtaac atctgatact aaggaaatta
    25621 cggatcaaga tgttgaaaat gttgtcaaat cagctttgac aaagagtatg acacctgacc
    25681 gtgaagtcat tacctttatt cctgaagaat ttattgtgga tggtttccaa gggattcgtg
    25741 acccacgtgg catgatgggg gttcgccttg aaatgcgtgg tttgctttat acaggacctc
    25801 gtactatctt gcacaatttg cgtaagacgg ttgagcgtgc aggtgttcag gttgaaaatg
    25861 ttatcatttc accactagca atggttcagt ctgttttgaa cgaaggggaa cgtgaatttg
    25921 gtgctacagt gattgatatg ggggcaggtc aaacgactgt cgctacaatc cgtaatcaag
    25981 aactccagtt cacacatatt ctccaagaag gtggagatta tgtaactaaa gatatctcca
    26041 aggttttgaa aacctctcgc aaattagcgg aaggcttgaa actgaattac ggggaagcct
    26101 atccgcctct tgcaagcaaa gaaaccttcc aagtagaggt tattggagaa gtagaagcag
    26161 tcgaagtgac ggaagcctac ttgtcagaaa ttatttctgc acgaatcaag cacatccttg
    26221 aacaaatcaa gcaagaatta gatagaaggc gtctattgga cctccctggt ggtattgtct
    26281 taatcggtgg gaatgccatt ttaccaggta tggttgagct tgctcaggaa gtctttggcg
    26341 tccgtgtcaa gctttatgtt ccaaatcaag ttggtatccg taatccagcc tttgcgcatg
    26401 tgattagttt atcagaattt gcgggtcaat taacagaagt taatcttttg gctcagggag
    26461 cgataaaagg tgagaatgac ttaagtcatc agccaattag ttttggtggg atgctgcaaa
    26521 aaacagctca gtttgtacaa tcaacgcctg ttcaaccagc tcctgctcca gaagtagagc
    26581 cggtggcgcc tacagaacca atggcggatt tccaacaagc ttcacaaaat aaaccgaaat
    26641 tagcagatcg tttccgtgga ttgatcggaa gcatgtttga cgaataaaga ggaaaaataa
    26701 attatgacat tttcatttga tacagctgct gctcaagggg cagtgattaa agtaattggt
    26761 gtcggtggag gtggtggcaa tgccatcaac cgtatggtcg acgaaggtgt tacaggcgta
    26821 gaatttatcg cagcaaacac agatgtacaa gcattgagta gtacaaaagc tgagactgtt
    26881 attcagttgg gacctaaatt gactcgtggt ttgggtgcag gaggtcaacc tgaggttggt
    26941 cgtaaagccg ctgaagaaag cgaagaaaca ctgacggaag ctattagtgg tgccgatatg
    27001 gtcttcatca ctgctggtat gggaggaggc tctggaactg gagctgctcc tgttattgct
    27061 cgtatcgcca aagatttagg tgcgcttaca gttggtgttg taacacgtcc ctttggtttt
    27121 gaaggaagta agcgtggaca atttgctgta gaaggaatca atcaacttcg tgagcatgta
    27181 gacactctat tgattatctc aaacaacaat ttgcttgaaa ttgttgataa gaaaacaccg
    27241 cttttggagg ctcttagcga agcggataac gttcttcgtc aaggtgttca agggattacc
    27301 gatttgatta ccaatccagg attgattaac cttgactttg ccgatgtgaa aacggtaatg
    27361 gcaaacaaag ggaatgctct tatgggtatt ggtatcggta gtggagaaga acgtgtggta
    27421 gaagcggcac gtaaggcaat ctattcacca cttcttgaaa caactattga cggtgctgag
    27481 gatgttatcg tcaacgttac tggtggtctt gacttaacct tgattgaggc agaagaggct
    27541 tcacaaattg tgaaccaggc agcaggtcaa ggagtgaaca tctggctcgg tacttcaatt
    27601 gatgaaagta tgcgtgatga aattcgtgta acagttgttg caacgggtgt tcgtcaagac
    27661 cgcgtagaaa aggttgtggc tccacaagct agatctgcta ctaactaccg tgagacagtg
    27721 aaaccagctc attcacatgg ctttgatcgt cattttgata tggcagaaac agttgaattg
    27781 ccaaaacaaa atccacgtcg tttggaacca actcaggcat ctgcttttgg tgattgggat
    27841 cttcgccgtg aatcgattgt tcgtacaaca gattcagtcg tttctccagt cgagcgcttt
    27901 gaagccccaa tttcacaaga tgaagatgaa ttggatacac ctccattttt caaaaatcgt
    27961 taagtaaatg aatgtaaaag aaaatacaga acttgttttt cgagaagttg cagaggctag
    28021 tctgagtgct catcgagaga gtggttcggt ctctgtcatt gcagttacca agtatgtaga
    28081 tgtaccgaca gcggaagcct tgcttccgct aggtgttcat catatcggtg aaaatcgtgt
    28141 agataagttt ctggaaaaat atgaagcttt aaaagatcga gatgtgactt ggcatttgat
    28201 tggtaccttg caaagacgta aggtgaaaga tatcattcaa tacgttgatt atttccatgc
    28261 attggactca gtaaagctag caggggaaat tcaaaaaaga agtgaccgag tcatcaagtg
    28321 tttccttcaa gtaaatattt ctaaagaaga aagcaaacac ggtttttcga gagaggaact
    28381 gctggaaatc ttgccagagt tagccagact agataagatt gaatatgttg gtttaatgac
    28441 gatggcacct tttgaggcta gcagtgagca gttgaaagag attttcaagg cggcccaaga
    28501 tttacaaaga gaaattcaag agaaacaaat tccaaatatg cctatgactg agttaagtat
    28561 gggaatgagt cgtgattata aagaagcgat tcaattcggt tccacttttg ttcgtatagg
    28621 tacatcattt tttaagtagg agagaaccat gtctttaaaa gatagattcg atagatttat
    28681 agattatttt acggaggatg aggattcaag tctcccttat gaaaaaagag atgagcctgt
    28741 gtttacttca gtaaattctt cacaggaacc ggctctccca atgaatcaac cttcacagtc
    28801 ggctgggaca aaagagaaca atattaccag acttcatgca agacaacagg aattggcaaa
    28861 tcagagtcag cgtgcaacgg ataaggtcat tatagatgtt cgttatccta gaaaatatga
    28921 ggatgcaaca gaaattgttg atttattggc aggaaacgaa agtatcttga ttgattttca
    28981 gtatatgaca gaggtgcagg ctcgtcgttg tttggactat ttggatggag cttgtcatgt
    29041 tttagctgga aatttgaaaa aggtagcttc taccatgtat ttgttgacac cagtgaatgt
    29101 tattgtaaat gttgaagata tccgtttacc agatgaagat caacagggtg agttcggttt
    29161 tgatatgaag cgaaatagag tacgataatg atttttttaa ttcgtatgat ttataatgca
    29221 gtggatattt actccctgat tttggtagcc ttcgctgtca tgtcttggtt tccaggtgcc
    29281 tacgaatcca gtttaggtcg ttggattgta gcgttggtga aaccagtgct tgctcccttg
    29341 caacgcctgc ctttacagat agcgggtctt gatttatctg tttgggttgc gattgttttg
    29401 gttcgatttt taggagaaaa cctagtgcgt tttctggcga tgataggatg aataaaggga
    29461 tttatcagca tttctccata gaagatcgtc catttcttga caagggaatg gaatggataa
    29521 agaaggtaga agatagctat gctccttttt taactccttt tatcaatcct catcaggaga
    29581 agctattaaa gattttggcc aaaacctatg gtcttgcttg tagcagtagt ggggaattcg
    29641 tatcgagtga gtatgttcga gttttattat acccagatta tttccaacca gagttttcag
    29701 attttgaaat atctctccag gaaattgtgt attccaataa atttgaatat ttaacgcatg
    29761 ctaagatttt agggacagtc atcaatcaat tagggattga acggaaactt tttggagata
    29821 tcctagtaga tgaagaacgg gcgcagatta tgattaatca gcagtttctt cttctctttc
    29881 aagatggact aaagaaaatt ggtcgtatac ctgtttcgct ggaggaacgt cctttcaccg
    29941 agaaaataga taagctagaa cagtatcgag aactggattt atctgtgtct agttttcgat
    30001 tagatgttct tttatcaaat gttttgaaac tatctaggaa tcaagcaaac cagttgattg
    30061 aaaagaaact tgtccaagta aattatcatg tggtagacaa atcagattac actgttcaag
    30121 ttggagactt gattagtgtg agaaaatttg gtcgcttgag attacttcaa gataagggac
    30181 aaacgaaaaa agagaagaaa aaaataaccg tccagttatt attaagtaag tgaggaatag
    30241 aatgccaatt acatcattag aaataaagga caagactttt ggaactcgat tcagaggttt
    30301 tgatccagaa gaagtcgatg aatttttaga tattgtggtt cgtgattacg aagatcttgt
    30361 gcgtgcgaat catgataaaa atttgcgtat taagagttta gaagagcgtt tgtcttactt
    30421 tgatgaaata aaagattcat tgagccagtc tgtattgatt gctcaggata cagctgagag
    30481 agtgaaacag gcggcgcatg aacgttcaaa caatatcatt catcaagcag agcaagatgc
    30541 gcaacgcttg ttggaagaag ctaaatataa ggcaaacgag attcttcgtc aagcaactga
    30601 taatgctaag aaagtcgctg ttgaaacaga agaattgaag aacaagagcc gtgtcttcca
    30661 ccaacgtctc aaatctacaa ttgagagtca gttggctatt gttgaatctt cagattggga
    30721 agatattctc cgtccaacag ctacttatct tcaaaccagt gatgaagcct ttaaagaagt
    30781 ggttagcgaa gtacttggag aaccgattcc agctccaatt gaagaagaac caattgatat
    30841 gacacgtcag ttctctcaag cagaaatgga agaattacaa gctcgtattg aggtagccga
    30901 taaagaattg tctgaatttg aagctcagat taaacaggaa gtggaaactc caactcctgt
    30961 agtgagtcct caagttgaag aagagcctct gctcatccag ttggcccaat gtatgaagaa
    31021 ccagaagtag ctccagtgca tccgacaggt ccaacaccag ctacagaaac tgttgattca
    31081 gcaccgggat ttgaagcacc gcaagaatct gttacaattt tataagaaat attctgagaa
    31141 caatatctta tccttatatt cccagcgagc aggagatggt gtgagtcctg cattccctat
    31201 cgataagatt atcctctcaa aaactcaagt ctgaatctag taagatttga cgttccccac
    31261 gttacgggat aagagggaga aagactaaaa ctttttccga ataaaggtgg taccacgatt
    31321 ttcgtccttt ttggaagtcg tggtttttaa tttgttatta tttataaagg agataccatg
    31381 aaactcaaag acacccttaa tcttgggaaa actgaattcc caatgcgtgc aggccttcct
    31441 accaaagagc cagtttggca aaaggaatgg gaagatgcaa aactttatca acgtcgtcaa
    31501 gaattgaacc aaggaaaacc tcatttcacc ttgcatgatg gccctccata cgctaacgga
    31561 aatatccacg ttggacatgc tatgaacaag atttcaaaag atatcattgt tcgttctaag
    31621 tctatgtcag gattttacgc accatttatt cctggttggg atactcatgg tctgccaatc
    31681 gagcaagtct tgtcaaaaca aggtgtcaaa cgtaaagaaa tggacttggt tgagtacttg
    31741 aaactttgcc gtgagtacgc tctttctcaa gtagataaac aacgtgaaga ttttaaacgt
    31801 ttgggtgttt ctggtgactg ggaaaatcca tatgtgacct tgactcctga ctatgaagca
    31861 gctcaaattc gtgtatttgg tgagatggct aataagggtt atatctaccg tggtgctaag
    31921 ccagtttact ggtcatggtc atctgagtca gcacttgctg aagcagagat tgaataccat
    31981 gactgggttt caacttccct ttactatgcc aacaaggtaa aagatggcaa aggagttcta
    32041 gatacagata cttatatcgt tgtctggaca acgactccat ttaccatcac agcttctcgt
    32101 ggtttgacgg ttggtgcaga tattgattac gttttggttc aacctgctgg tgaagctcgt
    32161 aagtttgtcg ttgctgctga attattgact agcttgtctg agaaatttgg ctgggctgat
    32221 gttcaagttt tggaaactta ccgtggccaa gaactcaacc atatcgtaac agaacaccca
    32281 tgggatacag ctgtagaaga gttggtaatt cttggtgacc acgttacgac tgactctggt
    32341 acaggtattg tccatacagc ccctggtttt ggtgaggacg attacaatgt tggtattgct
    32401 aataatcttg aagtcgcagt gactgttgat gaacgtggta tcatgatgaa gaatgctggt
    32461 cctgaatttg aaggtcaatt ctatgaaaag gtagttccaa ctgttattga aaaacttggt
    32521 aacctccttc ttgcccaaga agaaatctct cactcatatc catttgactg gcgtactaag
    32581 aaaccaatca tctggcgtgc agttccacaa tggtttgcct cagtttctaa attccgtcaa
    32641 gaaatcttgg acgaaattga aaaagtgaaa ttccactcag aatggggtaa agtccgtctt
    32701 tacaatatga tccgtgaccg tggtgactgg gttatctctc gtcaacgtgc ttggggtgtt
    32761 ccacttccta tcttctacgc tgaagatggt acagctatca tggtagctga aactattgaa
    32821 cacgtagctc aactttttga agaacatggt tcaagcattt ggtgggaacg tgatgccaaa
    32881 gacctcttgc cagaaggatt tactcatcca ggttcaccaa acggcgagtt caaaaaagaa
    32941 actgatatca tggacgtttg gtttgactca ggttcatcat ggaatggagt ggtggtaaac
    33001 cgtcctgaat tgatttaccc agccgacctt tacctagaag gttctgacca ataccgtggt
    33061 tggtttaact catcacttat cacatctgtt gccaaccatg gcgtagcacc ttacaaacaa
    33121 atcttgtcac aaggttttgc ccttgatggt aaaggtgaga agatgtctaa atctcttgga
    33181 aataccattg ctccaagcga tgttgaaaaa caattcggtg ctgaaatctt gcgtctctgg
    33241 gtaacaagtg ttgactcaag caatgacgtg cgtatctcta tggatatttt gagccaagtt
    33301 tctgaaactt accgtaagat tcgtaacact cttcgtttct tgattgccaa tacatctgac
    33361 tttaacccag ctcaagatac agtcgcttac gatgagcttc gttcagttga taagtacatg
    33421 acgattcgct ttaaccagct tgtcaagacc attcgtgatg cctatgcaga ctttgaattc
    33481 ttgacgatct acaaggcctt ggtgaacttt atcaacgttg acttgtcagc cttctacctt
    33541 gattttgcca aagatgttgt ttacattgaa ggtgccaaat cactggaacg ccgtcaaatg
    33601 cagactgtct tctatgacat tcttgtcaaa atcaccaaac tcttgacacc aatccttcct
    33661 cacactgcgg aagaaatttg gtcatatctt gagtttgaaa cagaagactt cgtccaattg
    33721 tcagagttac cagaggctca aacttttgct aatcaagaag aaatcttgga tacatgggca
    33781 gccttcatgg acttccgtgg acaagcacaa aaagccttgg aagaagctcg taatgcaaaa
    33841 gttatcggta aatcacttga agcacacttg acagtttatc caaatgaagt tgtgaaaact
    33901 ctactcgaag cagtaaacag caatgtagct caacttttga tcgtgtctga gttgaccatc
    33961 gtagaaggac cagctccgga agctgccctt agcttcgaag atgtagcctt cacagttgaa
    34021 cgtgctactg gtgaagtatg tgaccgttgc cgtcgtatcg acccaacaac agcagaacgc
    34081 agctaccagg cagttatctg tgaccactgt gcaagcatcg tagaagaaaa ctttgcggaa
    34141 gcagtcgcag aaggatttga agagaaataa gattgaaaag tctaggcaaa attcaatttg
    34201 agaagaaaag acaactaatt ttatagtcta ttaaacgcat tgtatcacgt ttttgaatac
    34261 ctgatatgat gcgtttttta tttattttaa aaatttgcga ggtatgactt tttatactca
    34321 acaagaatca aagagaaact tagcaatcta acagtagtaa g
//
LOCUS       DAVKXA010000018        33702 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKXA010000018 DAVKXA010000000
VERSION     DAVKXA010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.018"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            126..974
                     /locus_tag="VW883_000941"
     CDS             126..974
                     /locus_tag="VW883_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0274105.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWVVGDLARLPIKDAN
                     MDILLDIFSPANYGEFHRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            1598..2170
                     /locus_tag="VW883_000942"
     CDS             1598..2170
                     /locus_tag="VW883_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274106.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(3215..5473)
                     /gene="glgP"
                     /locus_tag="VW883_000943"
     CDS             complement(3215..5473)
                     /gene="glgP"
                     /locus_tag="VW883_000943"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0274107.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYKVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(5499..7016)
                     /gene="malQ"
                     /locus_tag="VW883_000944"
     CDS             complement(5499..7016)
                     /gene="malQ"
                     /locus_tag="VW883_000944"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0274108.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7566..8837
                     /locus_tag="VW883_000945"
     CDS             7566..8837
                     /locus_tag="VW883_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0274109.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            8948..10240
                     /locus_tag="VW883_000946"
     CDS             8948..10240
                     /locus_tag="VW883_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0274110.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            10242..11084
                     /locus_tag="VW883_000947"
     CDS             10242..11084
                     /locus_tag="VW883_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0274111.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            11337..12137
                     /locus_tag="VW883_000948"
     CDS             11337..12137
                     /locus_tag="VW883_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0274112.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            12147..13133
                     /locus_tag="VW883_000949"
     CDS             12147..13133
                     /locus_tag="VW883_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0274113.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            13269..13349
                     /locus_tag="VW883_000950"
                     /pseudo
     CDS             13269..13349
                     /locus_tag="VW883_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(13559..14500)
                     /locus_tag="VW883_000951"
     CDS             complement(13559..14500)
                     /locus_tag="VW883_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0274114.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(14478..16241)
                     /gene="aspS"
                     /locus_tag="VW883_000952"
     CDS             complement(14478..16241)
                     /gene="aspS"
                     /locus_tag="VW883_000952"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0274115.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(16477..16557)
                     /locus_tag="VW883_000953"
                     /pseudo
     CDS             complement(16477..16557)
                     /locus_tag="VW883_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(16593..16823)
                     /locus_tag="VW883_000954"
     CDS             complement(16593..16823)
                     /locus_tag="VW883_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274116.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(16841..17482)
                     /locus_tag="VW883_000955"
     CDS             complement(16841..17482)
                     /locus_tag="VW883_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0274117.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRILIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(17494..18228)
                     /locus_tag="VW883_000956"
     CDS             complement(17494..18228)
                     /locus_tag="VW883_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0274118.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(18231..18428)
                     /locus_tag="VW883_000957"
     CDS             complement(18231..18428)
                     /locus_tag="VW883_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274119.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(18428..18634)
                     /locus_tag="VW883_000958"
     CDS             complement(18428..18634)
                     /locus_tag="VW883_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0274120.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(18644..18958)
                     /locus_tag="VW883_000959"
     CDS             complement(18644..18958)
                     /locus_tag="VW883_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274121.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEFVNVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(19228..19308)
                     /locus_tag="VW883_000960"
                     /pseudo
     CDS             complement(19228..19308)
                     /locus_tag="VW883_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(19299..20588)
                     /locus_tag="VW883_000961"
     CDS             complement(19299..20588)
                     /locus_tag="VW883_000961"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0274122.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFATKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(20666..21913)
                     /locus_tag="VW883_000962"
     CDS             complement(20666..21913)
                     /locus_tag="VW883_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0274123.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWIVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLDLSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(22104..22955)
                     /gene="rgg"
                     /locus_tag="VW883_000963"
     CDS             complement(22104..22955)
                     /gene="rgg"
                     /locus_tag="VW883_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0274124.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKFDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKIEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            23079..23420
                     /locus_tag="VW883_000964"
     CDS             23079..23420
                     /locus_tag="VW883_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0274125.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            23478..23558
                     /locus_tag="VW883_000965"
                     /pseudo
     CDS             23478..23558
                     /locus_tag="VW883_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(23809..25512)
                     /gene="ilvD"
                     /locus_tag="VW883_000966"
     CDS             complement(23809..25512)
                     /gene="ilvD"
                     /locus_tag="VW883_000966"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0274126.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(25745..26677)
                     /locus_tag="VW883_000967"
     CDS             complement(25745..26677)
                     /locus_tag="VW883_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0274127.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSTIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(26674..27531)
                     /locus_tag="VW883_000968"
     CDS             complement(26674..27531)
                     /locus_tag="VW883_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0274128.1"
                     /translation="MILSENREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(27535..28881)
                     /locus_tag="VW883_000969"
     CDS             complement(27535..28881)
                     /locus_tag="VW883_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0274129.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACIIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(28894..29178)
                     /locus_tag="VW883_000970"
     CDS             complement(28894..29178)
                     /locus_tag="VW883_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0274130.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(29182..31212)
                     /locus_tag="VW883_000971"
     CDS             complement(29182..31212)
                     /locus_tag="VW883_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0274131.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLTDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            31404..32411
                     /locus_tag="VW883_000972"
     CDS             31404..32411
                     /locus_tag="VW883_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0274132.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNGNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            32414..32614
                     /locus_tag="VW883_000973"
     CDS             32414..32614
                     /locus_tag="VW883_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0274133.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            32766..32948
                     /gene="rpmF"
                     /locus_tag="VW883_000974"
     CDS             32766..32948
                     /gene="rpmF"
                     /locus_tag="VW883_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0274134.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            32964..33113
                     /gene="rpmG"
                     /locus_tag="VW883_000975"
     CDS             32964..33113
                     /gene="rpmG"
                     /locus_tag="VW883_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0274135.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(33593..>33702)
                     /locus_tag="VW883_000976"
     CDS             complement(33593..>33702)
                     /locus_tag="VW883_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0274136.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT        10568 a         7134 c         6016 g         9984 t
ORIGIN      
        1 cggcaaggcg acgttgacgt ggtttgaatt tgattttcga agagtattag ttttatttct
       61 actgaatctc ccatctactt attcctaaag ttgctttcat tttcctcttt tgatacactt
      121 aaactatgaa tacaaatctc aagcccaaac ttcagcgttt tgcttctgcg actgcctttg
      181 cctgccctat ctgtcaagaa aatctgactc tgttagagac taatttcaag tgctgcaacc
      241 gtcattcttt tgacttggcg aaatttggct atgtcaatct agcacctcaa atcaagcaat
      301 ccgctaacta tgacaaggaa aattttcaaa accgtcaaca aatcctagaa gccggctttt
      361 accaagctat cttagatgct gtatctgact tgcttgcaag ctcaaaaact accacaacaa
      421 ttttggatat cggttgtggt gaaggattct attctcgcaa actacaagaa agtcactctg
      481 aaaaaacttt ctatgccttt gacatctcca aagattcagt ccaaatcgct gctaaaagtg
      541 aacccaactg ggcagtcaat tgggtcgttg gcgacttggc acgccttcct ataaaagacg
      601 ctaacatgga tattctgctt gatatcttct cacctgccaa ctatggagaa tttcatcgcg
      661 ttttatccaa agacggtatc ttgataaagg ttatcccaac tgaaaatcac ctcaaagaaa
      721 tccgtcaaag agtacaggac cagctgacaa acaaggagta ttctaaccaa gatatcaagg
      781 agcatttcca agaacacttt accatcctat ctagtcaaac tgcctctctg actaagacta
      841 tcacagcaga acaactccaa gccctactca gtatgactcc tctcctcttt cacgttgacc
      901 agagcaagat tgactggagc caactgacag agattaccat cgaagcagag attctggttg
      961 ggaaagcatt ctaaactaga cttcccaaag gtataaaact taccgaaaat cttcaatatt
     1021 acaaaaacgc ataagaacag gtgcttaaaa accttaatct tatgcgtttt gttatagttt
     1081 tcatacacat taaggggaaa tagttgaaat cagttctttt aataaccatt gaataccata
     1141 tactacattt accccaaata tgatatagac cgtataaatc aagtatttcg atttttcccg
     1201 cctcaaagaa tagatcttat acaaaataaa taaatttaaa ataataaata atagagacaa
     1261 aatcttcctc caaaatcaat attaaaagta gccagtcaat catagttcta atctttattt
     1321 tcgattcgaa attacaaact tatcaatgaa caataagtga tataaggcca gtaccagacc
     1381 ccaaacgcta ccacgaaaag agaattcttg atgattgata gtaaacaaat catggttacc
     1441 aatatagagg caggtcaaaa taacaaataa aatccaaaat aaatccgtcc atttatattt
     1501 tgaaaaatat ttttttaaca taatagcata tttttttgac tataataaca gtatatgata
     1561 aaatgtaagc agatacaaat aaaaaggaga aaagctcatg aacaaattaa tgaaatttat
     1621 ttcggttttt ttgacgtcaa ttgtgttaat tgtatcagcg attccaagtg tttcagctgt
     1681 atacgcttct gaacaagtat cacaaattga aacaaatatg gaacttcaac ctgtcacttc
     1741 tctaacagaa gaacaaatca atacacttgc aaacgaaatc caatcttttc atccagacgt
     1801 ctcacaacaa tggatcaaag aagtaattaa ccgacaatta caaggcgatt atacaatccc
     1861 acctacatac tctccattta gagcagcttg gcaaggtatt acagttaatc aaatgggtgc
     1921 tctattagat actgcaatag ctttagcatt aggaggaact actgcaggcc ttgcaaatct
     1981 aattaaagta aaaggaaaac atgcagcaaa aagtgctatt cgttcagcaa tttctagata
     2041 tctaggtagt tggtttgtaa atgatgttgc tttagaattc gctatgaatt tattatcacc
     2101 ggggacttat ttagcacaat tatgggataa aaatgatgcc attcctaaca acggaaggat
     2161 taacttttaa tcatgagata tacaataaaa ttaattgggt ataacgtatt ttcgttgttt
     2221 atattcttta tcttatcaat gttgtttaaa gttcccttta ggtggtggat cagcattgca
     2281 atgacgactt cgtcgtacat tgtatataat tacttaaaga aaaagagaga aaaggaatga
     2341 tcttatacca gatcattcct tttctgcttt ctgtaaatcc ctcggagtgt gtttggcgct
     2401 ttgatacgaa gtgtcaaagc tgtataaacg ttactatttc caaaaaagta acagaaaatt
     2461 cctgctttgt aggactgctt tgggtgagta atagacatgt cgactcaccc tatctcctga
     2521 tggcgaaaag aatttagcaa tggtgcaagt tgttctgaac tcgagaaaaa acatgccgaa
     2581 atcgaagaaa agcgtgcaga acttgaagcg aagaagcaag aaatgttgaa tcgcttggat
     2641 aaatagaatt tagaaaacag aaaaaactaa aaagaatgta gggtttattt ccctacattc
     2701 ttaaaataac ttagtacata aatgacaatg ctgccactgc cgtcaatatt gcaaaaacta
     2761 ttttccaaat ttttttattt tttccaaaaa tcttatcagg taacaagctt attacaagaa
     2821 aggtaataaa caacaccaat ttaagtgtgt atatcataaa aacaccttct ttcctacaat
     2881 tatattataa tactttatgt aagcgaatac aagagatatg aggtaaccaa ctacgaaaaa
     2941 atataaggct gaagacagta aaaaccagca tttaaagcct tcactgtatc taggatttcc
     3001 ctatttttag acaagattga cccaaatcca cagcatttaa aaaagcgaat ttcaatcgaa
     3061 actcactttt ttacaaaatg tattagtata aatttgtatc ttatactcaa tgaaaatcaa
     3121 agagcaaact aggaagctag ccgcaggttg ctcaaagcac cgctttgagg ttgcagataa
     3181 agctgacgtg gtttgaagag attttcgaag agtattagtt caagtgccag atgtcttcat
     3241 tatactgagc gattgtacgg tcagatgaga agaatcctgc tttagaaatg ttaacgatga
     3301 ctttatccaa ccatgcgtca cggtcttcgt agtcagcaag catttgctct ttgactttga
     3361 tgtagtcttc caaatcaaga agagtcatga accagtcttt gttgatcaat tcattgtaaa
     3421 gacgttccaa gcgctctttg tttccagctg caagaactgc atcactaacg atgaagtcaa
     3481 ccaatggttt gatagcttca cgagcgtaga attcgcttga tttatatgct gcttttgcgt
     3541 aaaggtcgat aacagtttct gaatcttcac caaagatgta gatgttttcg tcaccaacca
     3601 actcagcgat ttccacgtta gctccgtcca tagtaccaag tgtcaaagct ccgttcaaca
     3661 tgaatttcat gttaccagta cctgaagctt ctttagaagc aagtgagatt tgttctgaga
     3721 tatcacatgc tgggataagg aagcttgctg cagtaacgtt gtagttttca accataacta
     3781 cttgcaagtg tggagctact gctggatcgt tagcaataac ttctgacatg caaaggatca
     3841 agtgaatgat atcttgagcg attgtgtagg ctggagctgc tttaccacca aagaagattg
     3901 taattgggcg agcagggatg ttaccagctt tgatgtcaag gtatttgtgg attacgtaca
     3961 aagcgttcat ttgttggcgt ttgtactcgt gaagacgttt gatttggata tcaaagatag
     4021 aatttgaatt gatttccaca ccttggtgtt ctttcaagtg acgagccaat ttacgtttgt
     4081 tgtgagcctt gatgctttcc aatttttctt tgacagctgc tttgtcttca taagacaaaa
     4141 gtttttcaag ctcatctgct tcatggtgcc aaccatctcc aagaatctca tccaagtagt
     4201 gagacaatct tgggttagca tgcataagcc aacgacggaa agtgataccg tttgttttgt
     4261 tgttgaactt ttctgggtaa aggtcgtaga aggctttcaa ctcagaattt ttcaagattt
     4321 cagtatggag tgctgcaacc ccgttaacac tgtatccgta gtggatatcc atgtgagcca
     4381 tgtgaacacg tccgctctca tcgatgattt gaacagctgg atctttgtac tctgccttca
     4441 cacgacggtc caattcttcg atgattggta ccaagtgagg aaccacttct tgcaagaatt
     4501 caagaggcca tttttcaagc gcttcagcaa ggattgtgtg gttagtgtag gcagtcatgc
     4561 tacgaacaat tgaaattgct tcgtcaagat cgataccacg tgcagtcaaa agacgaatca
     4621 attcaggaat caccattgat gggtgagtat cgttgatttg gacaactgcg tagtcagcaa
     4681 ggtcatgcaa gttgcttcct ttttcgattg cttcgtcgat gatcaattgc gcaccgtttg
     4741 aaaccatgaa gtattgttgg aagatacgga gcaattcacc ttgacggtca ctatcatctg
     4801 ggtaaaggaa gagagtcaag ttgcgagcga tatctgtctt gtcaaagttg ataccatctt
     4861 taataataga agaatcaact gaatccaagt caaacaaacg caagcggttt ttagtcgctg
     4921 tttcataacc agtaacatca atatcgtaaa gagttgatgt caaagtaaag tctgcaaatg
     4981 gtactttgta gctacggctt gagcgaacca accagttttg ctctgtcaac catgcatttg
     5041 gaattgtttc ttgttggttg tttttaagaa cttgttggaa aagaccaaag tggtagttaa
     5101 gaccaacacc gtcaccattc aaaccaagag tagcaattga gtcgataaag caggcagcca
     5161 aacgtcccaa accaccatta ccaagagatg gttccaattc aacttcttca acttcgatca
     5221 agtctttacc tgcagctgca agttcttttt taacatcgtc gtaaagacca aggttaatca
     5281 agttgtttga caagagttta ccaatcaaga actcagctga gatgtagtaa acttttttct
     5341 taccagtgtt gactggtttt tggctgcttg caagcttgct gtagttaaga agagcaaggt
     5401 aaagctcttc attgctacat tctgcaatgg ttttattgta acgattttgt acaaattctt
     5461 gtagtgataa catgtttagt tgtctcctga ttattgtctt atttctttaa atctaccaaa
     5521 ttttcattaa ttcggcgata aattgttgtc aagtcaagca aaccttcctc gacagctggt
     5581 gtcaattgat cttcagtcat acgccaagac cagtttccac caagggtaga tgggaagttc
     5641 atacgagctg cctcatccaa ttctagtaaa tcttgcatag ttgcaattgc cataaagcta
     5701 actgatgaaa atactgtacg aagcatagcg tgtaccactg tttcgtattc tttacggttc
     5761 gtgtaacgag ccatgtactc acgagtcgca tcatcaatct cattacggta ccaaccaaga
     5821 accgtattgt tatcgtgtgt tcctgtgtac ataactgagt tagcaggtgc caagtgtggg
     5881 ctatcaatgc tttcgtcttc tgggttgaag gcaaattgaa gaatcttcat tcctgggaag
     5941 ccagtacgtt cacgcaattc gatcacttca tctgtcatga agccaaggtc ttctgcgatg
     6001 atgtttagct caccaagttc ttccttaacg gctgcaaaaa gcttgtagcc tggacctttc
     6061 acccactcac caggtgctgc tgtatcggaa ccagcaggga tttcccagta agattcgaag
     6121 ccacggaagt ggtcgatacg aacgatatcg tagattttga agctttcacg caagcgttca
     6181 atccaccatt tgtagccgtc tttgtccatt gcttcccagt catagattgg attaccccaa
     6241 agctgaccag ttacagaaaa ctcatctggt gggcatcctg cgatacaagt agccttacca
     6301 ttgacatctg ttttgaagag atgtggattt gcccacatat cacttgaatc ttccgctacg
     6361 tagattggca tgtccccaac gatttcgatg tggttgtcgt tagcgtaagc tttcaatttc
     6421 aaccattgtt ggaagaagaa gtattgagtc acacggtggt aaaccaactt gtctgccaat
     6481 tgctcacgat agctttcaag tgctgaagct ttacgagcac gagcatctgc atctggccat
     6541 tcagtccaag caagattgtc aaaatactct ttgatagcca tatactcagc aaagagctca
     6601 agccatgatt ggttgtcttg agcaaatttc tcaaaatctt taacatctcc gacttcaaag
     6661 aaacgtttca ccgctttttc taaaagagga cgacgtgcat agtagatttt agcatagtca
     6721 acttcagacg catcgctacc aaagtcaact ccttcaaggt cacttgcttc caacaaacct
     6781 tgctccacca agatatctaa atcgataaaa tgagtgtttc ctgcgaaggc tgagaaagat
     6841 tggtaaggag aatccccgta actagttgct cctaatggaa ggatttgcca gtaacgttgt
     6901 tttgtacgga ccaagaaatc aacgaagtcg taagcacttt gaccaaatga tccgattccg
     6961 taagctcctg gaagagaaga gatgtgcatc aacacaccac tttgacgttt tttcataata
     7021 gcacctcgtg tgttaaaata atggaacgtt gcgtattttt cagacgcaaa cgtttgcgtt
     7081 acttataagt atactccttt tcaagcataa ttgcaagcgt ttttaaaaaa cttttttgat
     7141 tatttttaag gagactaact cattttagca aagataactt aaaactatct aatcctaaag
     7201 tttgactctc acgagacagt atacaaagta caaaacctcc ttagggagct tgaatttata
     7261 tgcaacaaag cacaaacgtc tatagaaaat agatagggat tagaaacagg gaggtagccc
     7321 ctcctggttt ccctctttag acagattcca tatattttta ttaaaaatac tgtattctta
     7381 tctatttcat acttttcttc tattaaaatg caaaattatg ctatcaaatc aagcttaaaa
     7441 attttttaaa atttttacaa aaaatacttg caaccgtttt ctatttgtgc tatactaagc
     7501 tcataaagga aaacgtttgc gtttccttat caataaaact tgctattctt tgggaggaat
     7561 acactatgtc atctaaattt atgaagagca ctgcggtgct tggaactgtt acacttgcta
     7621 gcttgctttt ggtagcttgc ggaagcaaaa ctgctgataa gcctgctgat tctggttcat
     7681 ctgaagtcaa agaactcact gtatatgtag acgagggata taagagctat attgaagagg
     7741 ttgctaaagc ttatgaaaaa gaagctggag taaaagtcac tcttaaaact ggtgatgctc
     7801 taggaggtct tgataaactt tctcttgaca accaatctgg taatgtccct gatgttatga
     7861 tggctccata cgaccgtgta ggtagccttg gttctgacgg acaactttca gaagtgaaat
     7921 tgagcgatgg tgctaaaaca gacgacacaa ctaaatctct tgtaacagct gctaatggta
     7981 aagtttacgg tgctcctgcc gttatcgagt cacttgttat gtactacaac aaagacttgg
     8041 tgaaagatgc tccaaaaaca tttgctgact tggaaaacct tgctaaagat agcaaatacg
     8101 cattcgctgg tgaagatggt aaaactactg ccttcctagc tgactggaca aacttctact
     8161 atacatatgg acttcttgcc ggtaacggtg cttacgtctt tggccaaaac ggtaaagacg
     8221 ctaaagacat cggtcttgca aacgacggtt ctatcgtagg tatcaactac gctaaatctt
     8281 ggtacgaaaa atggcctaaa ggtatgcaag atacagaagg tgctggaaac ttaatccaaa
     8341 ctcaattcca agaaggtaaa acagctgcta tcatcgacgg accttggaaa gctcaagcct
     8401 ttaaagatgc taaagtaaac tacggagttg caactatccc aactcttcca aatggaaaag
     8461 aatatgctgc attcggtggt ggtaaagctt gggtcattcc tcaagccgtt aagaaccttg
     8521 aagcttctca aaaatttgta gacttccttg ttgcaactga acaacaaaaa gtattatatg
     8581 ataagactaa cgaaatccca gctaatactg aggctcgttc atacgctgaa ggtaaaaacg
     8641 atgagttgac aacagctgtt atcaaacagt tcaagaacac tcaaccactg ccaaacatct
     8701 ctcaaatgtc tgcagtttgg gatccagcga aaaatatgct ctttgatgct gtaagtggtc
     8761 aaaaagatgc taaaacagct gctaacgatg ctgtaacatt gatcaaagaa acaatcaaac
     8821 aaaaatttgg tgaataaaaa atttgttcaa ggggggtgga aatcaaatcc ccctttgaat
     8881 ttatcaatag agacacaaat aatttagctt tcttataaaa aagtagtatc ctatgaaagg
     8941 agttaatatg gaaaagcaac aacctagtaa agcagccctg ctgtctatca ttcctgggtt
     9001 aggacagatt tacaataaac aaaaagccaa aggttttatc ttccttggtg taaccatcgt
     9061 atttgtcctt tacttcctag cacttgcaac ccctgaattg agcaacctca tcactcttgg
     9121 tgacaaacca ggtcgtgata attccctctt tatgctgatt cgtggtgcct tccatctaat
     9181 ctttgtaatc gtttatgtac tcttttattt ctcaaatatc aaagatgcac atacgattgc
     9241 aaaacgcatt aacaatggaa ttccagttcc acgcacactc aaagacatga tcaaagggat
     9301 ttatgaaaat ggcttccctt acctcttgat cattccatct tatgttgcca tgaccttcgc
     9361 gattatcttc ccagttatcg taaccttgat gatcgccttt accaactacg acttccaaca
     9421 cttgccacca aacaagttgt tggactgggt tggtttgacc aactttacaa acatttggag
     9481 cttgagtacc ttccgttctg cctttggttc tgttctttct tggactatca tttgggcttt
     9541 ggcagcttct actttacaaa tcgtaattgg tatcttcaca gctatcattg ccaaccaacc
     9601 atttatcaaa ggaaaacgta tctttggtgt tattttcctt cttccttggg ctgtcccagc
     9661 cttcatcact atcttgacat tctcaaacat gtttaacgat agtgtcggtg ctatcaacac
     9721 tcaagtattg ccaatcttgg ctaaattcct tcctttcctt gatggagctc ttattccttg
     9781 gaaaacagac ccaacttgga ctaagattgc cttgattatg atgcaaggtt ggctcggatt
     9841 cccatacatc tacgttttga ctttgggtat cttgcaatct attcctaacg acctttacga
     9901 agcagcttat attgacggtg ccaacgcttg gcaaaaattc cgcaacatca ctttcccaat
     9961 gattttggct gttgcggcac ctactttgat tagccaatac accttcaact ttaacaactt
    10021 ctctatcatg tacctcttca atggtggagg acctggtagt gtcggaggtg gagctggttc
    10081 aaccgatatc ttgatctcat ggatctaccg tttgacaaca ggtacatctc ctcaatactc
    10141 aatggcggca gctgttacct tgattatctc tatcattgtc atctcaatct ctatgatcgc
    10201 attcaagaaa ctacacgcat ttgatatgga ggacgtctaa gatgaataac tcaattaaac
    10261 tcaaacgtag actgactcaa agccttactt acctttacct gattggtcta tcaattgtaa
    10321 ttatctatcc actgttgatt accattatgt cagcctttaa agcaggtaac gtctcagcct
    10381 ttaaactaga tactaatatc gacctcaatt ttgataactt taaaggcctc ttcactgaaa
    10441 ccttgtacgg tacttggtac ctcaacactt tgattatcgc cttaattacc atggctgttc
    10501 aaacaagtat catcgtactt gctggttatg cttacagccg ttacaacttc ttggctcgta
    10561 aacaaagttt ggtcttcttc ttgatcatcc aaatggtgcc aactatggcc gctttgacag
    10621 ccttcttcgt tatggcgctt atgttgaacg cccttaacca caactggttc ctcatcttcc
    10681 tctacgttgg tggtggtatc ccgatgaatg cttggctcat gaaaggctac ttcgatacag
    10741 ttccaatgtc tttagacgaa tctgcaaaac tagacggtgc aggacacttc cgccgcttct
    10801 ggcaaattgt tctaccactt gttcgcccaa tggttgccgt acaagctctc tgggccttca
    10861 tgggaccttt cggggactac atcctctcta gtttcttgct tcgtgagaaa gaatacttta
    10921 ctgttgccgt aggtctccaa accttcgtta acaatgcgaa aaacttgaag attgcctact
    10981 tctcagcagg tgctatcctc atcgcccttc caatctgtat tctcttcttc ttcctacaaa
    11041 agaactttgt ttcaggactt acaagtggtg gcgacaaggg ataatttatc cccgccaccc
    11101 tttttcattt tatactcttc gaaaatctct tcaaaccacg tcagctttat ctccaacctc
    11161 aaagttgtgc tttgagcaac ctgtggctag tttgcacttt gattttcatt gattattagc
    11221 aattgtcact gtaaataata tccttgtagc aagcaatttt tctcctagac ttgaaataaa
    11281 gcgcatttct ctatataata atactcatat agaaaacacc ttttagaaag atacctatgc
    11341 ttccatatcc attttcctat ttttcaagta tttgggggtt tcgtaagccc ctgtccaaac
    11401 gtttcgagct caactggttt caacttctct ttaccagtat cttccttatc agcttgtcta
    11461 tggtacccat tgctatccaa aacagctccc aggagaccta tccgctagaa acttttatcg
    11521 ataatgtcta tgaacctctg acaaatgagg ttgtccagga tctctctgaa catgctacaa
    11581 ttgtcgatgg cacattaact tatactggaa cagctagtca agccccttct gttgtgattg
    11641 gtccaagtca aatcaaggaa ttacctaagg acttgcaact gcatttcgat acaaatgagc
    11701 tagtcatcag caaggaaagc aaggaactga cccgcatctc ttaccgagcc attcagactg
    11761 agagtttcaa aagcaaagac agcttgaccc aagcaatttc taaagactgg taccaacaaa
    11821 atcgtgtcta tatcagcctc ttcctagttc tcggtgcgag cttcctcttt ggtttgaatt
    11881 tctttatcgt ctctctagga gctagtcttc tcctttatat cactaagaaa tcacgcctct
    11941 tttcatttag aacctttaaa gagtgctatc actttatctt gaactgttta ggattgccga
    12001 ctctgattac acttattttg ggattatttg gccaaaatat gacaaccctg attactgtac
    12061 aaaatattct ttttgttctg tatctggtca ctatctttta taaaacacat ttccgtgatc
    12121 caaattacca taaataggag atttttatgc ccgttacgat taaagacgtg gccaaggctg
    12181 ctggtgtttc gccttcaacc gtaacccgtg ttattcaaaa taaatcaacc attagcgacg
    12241 aaacaaaaaa acgcgttcgc aaagctatga aggaactcaa ctaccaccca aacctcaacg
    12301 ctcgtagctt ggtaagcagc tatactcagg ttatcggatt agttcttcct gatgactcag
    12361 acgccttcta ccagaatcct ttctttccat cggttctacg tggcatctct caagtcgcat
    12421 ctgaaaacca ctatgccatt cagatagcaa cagggaaaga tgagaaggag cgtctcaacg
    12481 ctatttcaca aatggtctac ggcaagcgtg tagatgggct aatctttctc tatgcccaag
    12541 aagaagaccc tctcgtaaaa ctcgtcgcag aagaacagtt ccccttcctt atcttaggta
    12601 aatctctatc tcctttcatc ccacttgtcg acaacgacaa tgttcaagct ggttttgatg
    12661 cgactgaata tttcatcaaa aaaggctgca aacgcattgc ctttatcgga ggaagtaaaa
    12721 agctcttcgt gaccaaagac cgtttaacag gctatgaaca ggcgcttaaa cattacaaac
    12781 ttaccactga caacaatcgc atctactttg ccgacgagtt tctggaagaa aagggctata
    12841 aatttagcaa gcgattattc aagcacgatc cacaaattga tgctatcatc acaaccgata
    12901 gcctcctagc tgaaggtgtt tgtaactata ttgccaaaca ccagctggat gtccctgttc
    12961 tcagctttga ctcggttaat cccaagctca acttggcagc ctatgtcgat atcaatagtt
    13021 tagagcttgg tcgtgtttcc cttgaaacta ttctccagat tattaatgat aataaaaaca
    13081 ataaacaaat ttgttaccgt caattgatcg cccacaaaat tatcgaaaaa taagagactg
    13141 ggcaaaaagt cgttaaaagc aaaaacgcat actatcaggt attgaaaaaa cttgatacta
    13201 tgcgttttat tgtgggaaga tttacttcct tttctactga aattgagttg ttacccaaga
    13261 tctttttata ctcaatgaaa atcaaagtgc aaactaggaa gctagccgca ggttgctcaa
    13321 aacatggttt tgaggttgta gatgaaactg acgaagtcag ctcaaaacat ggttttgagg
    13381 ttgtagatga aactgacgaa gtcagctcaa aacatggttt tgaggttgca gatagaactg
    13441 acgaagtcag ctcaaaacat ggttttgagg ttgcagatag aactgacgaa gtcagtaaca
    13501 tatatacggc aaggtgaagc tgacgtggtt tgaagagatt ttcgaaaagt attaatcact
    13561 aattatctat ctcaacaaat cttcctagaa tatgaacatt ttccgagaca gagacaaagg
    13621 agcttggatc cacttgtgtc ataatctgtt taaattcatt aaactctgca cgtgtaatga
    13681 cagtgattaa aactgccttt ctctcgtgat tataggttcc ttctgcatcg tggatcatgg
    13741 ttgctccgcg gtgcaatttt ttatggattt tttcaattac cttctctgga tgatttgtca
    13801 caatcatggc ctgcatacgc ttttgcttag taaagactgc gtctgtcaca cggctagaga
    13861 caaagatggt aatcatagaa taaagagcgt atttccaacc aaaggttaaa cctgctatca
    13921 gcatgatagt tccatttacc aagaaagaaa tactaccgac attcttaccc gttttcttgc
    13981 gaatagtcag gctgacgata tccgtcccac cactggagat attgtttcga agagcaaaac
    14041 caatccccaa acccataaca acacccccaa aaagggaatt gataatggga tcctccgtca
    14101 aggttgccac agggacaaac tggataaaga aggaactcat agataccgtg ataaaggtaa
    14161 agacggtgaa cttatggcca atctgatacc aagctaagac catcaaaggg aagttaatgg
    14221 cgtagaagct tagcgaaatc ggaatatgaa aaccaaacca gtgattactc aaggcagaga
    14281 taatctgtgc cagacctgtt gcaccactcg aatacacatg ccctggttgg aaaaagaaat
    14341 taactgctac tgctgataaa aaaccataga ccagagaggc cgaaatcttc tcatcatact
    14401 tttctcgaga gatactttgt aagacacgta aaatttttat ctgataagca aagcggcgca
    14461 gataatagcg ccaccgctta attcgttttg cttgtttcat cttcttctac ttgtaagctg
    14521 agttcctcta gttgtttgag agcgactgtt gatggagctt gtgtcattgg gtcagttgcc
    14581 ttgttgttct taggaaaggc aatgacttca cggatatttt cttctccagc aagcaacatg
    14641 acaaaacggt caagcccgat agccaaacca ccgtgtggtg ggaaaccata gtccatggct
    14701 tcaagaagga aaccaaactg gtcattggct tcttcagctg agaaaccaag agccttgaac
    14761 atgcgttctt gaaggtcttt ttggttgata cgaaggctac caccaccaag ctcataaccg
    14821 ttcaagacga tatcgtaagc aatggcacga accttagcca aatcaccttc taattcgtga
    14881 gcagtctctt cctgtggaag tgtgaatgga tggtgggcgc tcatgtagcg gccttcttct
    14941 tcagaccatt caaacatcgg ccagtcaacc acccaaagga agttgaactt atcattatca
    15001 atcaagccaa gctctttagc aatacgtcca cgaagggcac ccagtgttgc attagccact
    15061 tcaagcgtat ccgccacaaa gagaaccaag tccttatctt caagagcaag cgctgttgtc
    15121 aattcttctt ggataccagt caagaacttg gcaactggtc cgtttaattc tccatcaacc
    15181 accttgaccc aagcaagacc tttggcacca tactgtttgg ctacttccgt catcttgtcg
    15241 atgtctttac gtgaatagtt gtccgcagct cctttgacca caatcgcttt tacagcaagt
    15301 gcttctgaaa agactttaaa gtctacacct ttgaccactt ctgtcaagtc ctgaagcaac
    15361 atgtcaaaac gagtatctgg cttgtcagaa ccgtaaagag ccatagcatc atcgtatttc
    15421 atacgaggga acggtagcgt tacttcgatg ccttttgttt ccttcatcac gcgcgcgatc
    15481 aagccttctg taatatcttg gatttcttgc tcagtaagga aggacgtttc caagtcgacc
    15541 tgagtaaatt caggctggcg gtctccacgc aagtcctcgt cacggaaaca tttaacgatt
    15601 tggtagtaac ggtcaaaacc agcattcatc aagagctgtt tcgtgatttg tggactttga
    15661 ggaagagcgt aaaaatgccc cttattaaca cgagacggca ctaaataatc acgcgcccct
    15721 tcaggcgttg acttagaaag gaatggtgtc tccacgtcga taaactccaa ctcatccaag
    15781 tagttgcgga tagagtgggt caccttggca cgaagtttaa gattttccaa catttctgga
    15841 cgacgaaggt caaggtaacg gtaacgcaaa cgtgtatcgt catttgcctc aatgccatcc
    15901 ttaatctcaa atggtgttgt cttagctgtg ttaagcacaa taagagctgt cacgtttaac
    15961 tcaaccgcac cagttggcaa cttatcattg gcttgctcac gcgcagcgac ctgaccagtc
    16021 acctcaataa caaattcgct acgaaggctt tcagctgttg ccataacctc tgcagatact
    16081 ttttcagggt tgataaccaa ctgcatgatt ccttcacggt cacgaagatc gataaagatc
    16141 aaaccaccaa ggtcacgacg acggccaacc catcctttca aggttatttc ttgtccgatg
    16201 tgttcctcac gaacacgacc agcatacata ctacgtttca ttatttctct cctcttttat
    16261 tctgttacta ttttaccata aaagcgcagg ctcttcatga aaatcatcag aaaagtttgc
    16321 cagtctttaa aagtcaggtg aaagccctaa aaattagcgc taatactctt cgaaaatctc
    16381 ttcaaaccac gtcagcgtcg ccttaccgta ggtatggtta ctgacttcgt cagtttcatc
    16441 tacaacctca aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca
    16501 gtgttttgag caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa
    16561 tacaaaaatc cgatgaactt caccggactc ttttattttg aatttttgcc tgctttacgc
    16621 ttttcagcga tttcggctgc ctttcgaggc aagacaattt ccgttatgta agccgtccca
    16681 aaacgcagta cacctgcaat aggagcaaag acaactgcta gatagttata gaagaaatcg
    16741 cctttgaagg cataagctag cgctccaatg atgaaaaata gaacgactgc ctgaatcact
    16801 gctaataaaa ttactcgttt catgtgacct cctgactcta ttatagcatg agaatcatca
    16861 aaaagccgac taaattattc aaagcgtgaa gagaaatact gtagaccaga ccttttctgc
    16921 taatgtaagc caaacccaaa ctaaaaccaa ggctaaaata gacaaaaaat tgttgcacat
    16981 cacctggaaa atgaatcaag gcaaatagaa gactagatac cagaagaaaa atcaggattc
    17041 gtttactatt gtcctgctta ggaaagagat agcgtgctaa catccctcta aaaacaatct
    17101 cttccgtcaa aggagcaaaa ataaccacag caaagaatga gaaaagtggt tgagacaagg
    17161 tcaagtctgt cgctatttgc tgatttactg aaggatcatc tggcaagaag aattgaacga
    17221 ccagagataa gaaccaaacc aagacaggaa gccaaataaa tcgattaaag ccgctcttct
    17281 caatatgaac aggagccttc tgataccatt tgtaaatgcc gtacacatat actccagcca
    17341 aggccacata gagtagagta acagcatagg gtgaagcgcc taaagcaagc gacgcagtcg
    17401 cgagcccctg aataaagcca tagataaata aaaaggatag aagggctaga agaatccagc
    17461 caaggttttt aagtaatttc atagataact cctttatttg aaataacgtt ttaccatagg
    17521 taactgcatc acattgatat aaacatggat ggctcctaca agcaagaaag ctagtaactg
    17581 aatctctcct gtcaagaaag aaatgataat aagaaaaata tataaggctg gtaagacata
    17641 ttggtgtaat tggaataaaa ttcgaaaact ctgttccaaa ttagcctgac gctccccttc
    17701 atcataagaa tttatatagt tcaagacatc ctttggtgta gcgaaaaatt ccaaatcaaa
    17761 ctgacgaaca atcgcaatgg ttttaaaaag agatttttga gcgactaaga ataccacaaa
    17821 gagtaagaaa gaaaggaaaa atgtttgagg gtttgtatgc aatataatca cctcacttaa
    17881 tgaaataaaa atagccaatg gaatcgctac acctgtaata ttaaaagcaa tggttccaaa
    17941 ctcaagattc cgatacattt gcacataata ggtttcattc agatcgtcat ccatttcctc
    18001 ttgatacaag gaatgaaatt ttctgctttt ctttaagaaa ttgaaagtca aaaacatact
    18061 aatgaaacct atcagtaaac aaatagctga tatccatggc atcaaggctt ttacatctaa
    18121 aataatttcg tgggattcga cacgtgcctt aaacatccct acaaacatgc ccaagaaccc
    18181 ccccaagaca atagacatca aaaataacaa tctacgtttc tttttcatat tcattctcct
    18241 ttttcacttg ctagattttt ggatttcttt tcaatccatt cagttactgg gatgagagca
    18301 aagtagaccc aaacaaattg gtcgctttga tagggattaa accagcttag gtccatccca
    18361 atcagtagaa atacgctgac taataaagct atgaccacta cataataaat cactttatac
    18421 ttgttcatca ctcgtcctcc tccaaacgaa ataccgattc gactgtttcg ttgaaaattt
    18481 gagatatttt cagggcaatg ataatggatg gggtgtactc atcccgttct agtaggctaa
    18541 tggtctgtct ggaaacccct gccagtttgg ctaggtcggt ttgattgaga ccatcgcgag
    18601 ctcgaagctc ttttagacga ttttttagtt gcacgttaca cacctactct ccgtcaaatt
    18661 caacggtttg gatatcttca atacgttgca acttgaattt ttcttttccc gtattatcaa
    18721 cactacgtag tttgacccat tcctcatcaa cattcacaaa ttcccagtta tctggcccaa
    18781 tatacactcc cgttataatt ggttcctttc caatcatttc ttgtaataat ctcgacattt
    18841 ctgcgtttcc tttctctttt cgctcaagtt ttttgatttt attctctagt ttcttgattt
    18901 ttttagaatt attagaataa aagaaaatca taaatagtat aaatcctagt acccacatta
    18961 taactccttt ctgcttccta tttcttaact tgaattcatt gtaacatatc tttttctttt
    19021 tgacaagtat agctgtcaaa aagtttatga tttttgtcat tttgcaaaag aaaaaggtca
    19081 ggagtaagtt cctgaccact ttatctatca ttaatactct tctaaaatct cttcaaacca
    19141 cgtcagcttc accttgccgt aggtatggtt actgacttcg tcagtttcat ctacaacctc
    19201 aaaaccatgt tttgagctga cttcgtcagt tctatccata acttcaaaac agtgttttga
    19261 gcaatctgcg gctagcttcc tagtttgctc tttgattttt attgagtata aaatcctagt
    19321 ttttcaaaga tttctgaaaa gttttggctg attgtctcaa gtgacacttg cacttcttct
    19381 cgggtttggt tgttcttgac cgtcacttgt ccgctttcga cttcgctctc tcccagggtg
    19441 atgagggtct tagtcgcaaa gacatcggct gacttgaact gagctttgag cttacggttg
    19501 aggtaatcac gctctgcttt gaaaccttgt tggcgaaggg cttggactag ttctagggct
    19561 ttgacatttg ctccatcacc caagactgcg atatagacat ctagggcatt ttcgataggg
    19621 agggccacgc cttgtttttc aaggatgaga agcagacgct ctacaccaag cccaaaacca
    19681 aatccagcag tttcagggcc tccaaagtaa gcaaccaaac catcgtagcg accacccgca
    19741 cagactgtca agtcattgcc ctcaatctct gtgataaact cgaaaatggt gtggttgtag
    19801 tagtccagac cacgcaccat attggtatcg atgatgtaat ctactccaag attttccaac
    19861 atctgacgca cagcatcaaa atgagcttgg ctttcttcat caagaaagtc caagatagac
    19921 ggcgcattct ctactgccac cttgtcttct ttttccttag agtccaagac acgaagagga
    19981 ttttcctcca agcgacgttg gctatcctta gacaaggtct ccttgagcgg tgtcaaatag
    20041 tcaatcaagg cttggcggta ggctgcacgg ctctcaggat ttccaagagt gttgaggtgc
    20101 aatttgacac cttgaatacc gatttccttc aaaaaatggg ctgccataac gattgtttcc
    20161 acatcggtag ctggattgct agagccaaaa cactcaacac caatctggtg gaattggcgc
    20221 aagcgccctg cctgtggacg ctcataacgg aacataggtc ccatatagta gaacttgctt
    20281 ggcttttgca cttctggggc gaagagttta ttttccacat aggaacggac aacgggcgca
    20341 gttccttctg gacggagggt aatatgacgg tcacccttgt cataaaaatc gtacatttcc
    20401 ttggttacga tatccgttgt atctccgaca gagcggctga taacctcgta atgctcaaaa
    20461 ataggcgtgc gcacttctgc atagttatag cgcttgaaaa tctcacgggc aaagccctca
    20521 acgtactgcc acttagcaga ctcagcaggt aaaatatcct gcgttccttt tggtttttgt
    20581 aatttcatag ggaatcctct ttaaacttaa tagtcttatt ttaccataaa tagagggatt
    20641 aaaacagtaa gaaaaaaatt aggatttaga tatcattttt gagattaaga attgttaaaa
    20701 aaatagctag caaggaaaga ccaacaaata gcatccaagt caactgcatg ttccatacgg
    20761 ctactagtga aaaacaagct gttcccacag gtatggataa ggtaaacaat agacctaaaa
    20821 aattactagt acgagctaga acctctggag ctagattttt catgagcatg gcactaatct
    20881 ttggttgaac tttaccagac acatacagag taaagaagag aaatagcaaa ccaagcacga
    20941 cttgattgaa taaattagcc aaaccaacta gactaagtcc tacggtcgcc cacatcatca
    21001 atctaggcaa ggactgcttc ccaaaataag cattgcccgt aagactactg atgatgattg
    21061 ctactaaaac acagaattga ttgataaata gtgcctctgt ataagaaaaa ttcaagagag
    21121 aatggctcaa aaagaagata ttataaattc cacccaaagc gccacccaag gaattaataa
    21181 gcaagacagc aaagagcata aaaccaaagt ttttctgtcc acttttaaga aaaacgagac
    21241 gtaaatttcg gtaaattgtt aggaactggt ctttgataga aagcttctca ttttttaagt
    21301 tttcaccatc agcagatgac attgacaggc tcaatttgct ttttcctaaa aagaggatag
    21361 tggctgatac taggaaaaag caggcattga ttcccgcaac gagagaaaaa ttgttgaccg
    21421 atagatctaa gagccagact ccgaaagctt gaccaccaat agctgaaata taggtgatga
    21481 actgtgaaaa agaataagcc tccatcagat catcttcagc tactttttcc ttaataagag
    21541 gcatacgcag gccacctgca aaatcactga tgatatcact aatgacattg atcaaacaca
    21601 ggctagaaaa ggcaaagaga ctagcttgct gaacaactag ggctgctaga aaaaatagaa
    21661 ccgcctgaaa caaaccgcta tagactatcc atttgacctt gtccctcgtg taatctgccc
    21721 gaatccctgc aaaaactgta aagaaggtcg gaagaatcat gacaatattc gccatagcaa
    21781 cagcaaaaga tgcttgtgac aaggtcgatg catagacgat aaagaccagg ttgaaaatcg
    21841 aagcaccaaa agcattgaag aagcgtgata aagtcaaaat tctataagct ggatttctaa
    21901 acaatagttt catagataat ctccctcctt gttctaagtt ctacatcaag aatagcttta
    21961 gtatagcact tatgaatttg cgaaacgatt cttttgaata tatgcaacaa acaaaatgag
    22021 caaaaaaacg atagaacttt tgtaatgacc tgagagaggg caacagttct atcgcttcaa
    22081 attttttctt ggtttgcaga tactcaacat tcggtcgtat ttctatagta ttcggcagat
    22141 ttattacagc caagcatctc aaaaatacgg acagcatcct ctatcttttt ctgaccttcc
    22201 ttgactctac cttgcttgct atcaaggaga ccttctgccc acagataaac aattcggaaa
    22261 taggtctcat tttccttgta gaaatgctct tcgataacac gtttaaaata ataggcattg
    22321 gtaaattctt cacactcaat actagctaaa aagccattca atagtatagt atgaaaaagg
    22381 tttcgattgc cagacatttc cattagaaaa tcgaatttac gtaccatttc tcgtacatat
    22441 ctagtaaaaa gagaaacgga taaaaatgga gaactgactg aaaataaatt gagttcatag
    22501 attccccaga tctcggtaga aaacaaataa tcatgaagga cttttccttc ctctgctgtt
    22561 aagtctaccc tttcatctat gctcttcata taagacttga tcataatggc atttagaata
    22621 tgtttctgtt tgttgtgaga atgggcatgc ttttgatact ccctgcgata taagtcctca
    22681 agaggtgcta tattctttgg ttccaagaca tctgtaattt cttttctcaa ctcagaatct
    22741 gtatcatact ggaaacctct cgccagaaag aggatctcct ccacactggc agatatattt
    22801 tccagagcaa atagaaactt ttccaccgaa agctcactct gacctgtttc aaaacgggac
    22861 aacatagacg gcgaaaattg tcctccggtt gcttgtctca gtgagatatt tcttgattct
    22921 cgtaattgtc taaagacttt tccaatctgc tccatagact tccccttgat tccgtatttt
    22981 cttcatttta tcatattttt cagaaaattc atcaaaaact tgccaaattg tcagaattat
    23041 gagaaaatag aggatattta tcacgtggag ggactgctat gagagacgat atcaaaatca
    23101 atgaccgtgc tttggccttg caagaccaaa ttatcgaaaa actagagaaa gtttttgata
    23161 cagatgtgga attggatgtt tacaatctag gtctgattta tgaaatcaat ctggatgaaa
    23221 cggggctctg caagattgtc atgaccttca ccgatactgc ctgtgattgc gccgaaagcc
    23281 tacctattga aatcgtggca ggtctgaaac aaatcgaggg tatcaaagat atcaaggttg
    23341 aagttacctg gtcgcctgct tggaaaatca cacgaatcag tcgctatggc cgtattgccc
    23401 ttggattacc acctcgttaa gcaggccaat cacttttaaa gatgaaaaaa gcaagccgaa
    23461 aatggcttgc tttttgatac tcaatgaaaa tcaaagggca aactagaaaa ctagccgaag
    23521 gttgctcaaa acactgtttt gaagttatgg atagaactga cgaagtcagc tcaaaatact
    23581 gttttgaggt tgtggataga actgacgaag tcagctcaaa atactgtttt gaggttgtgg
    23641 atagaactga cgaagtcagc tcaaaatact gttttgaggt tgtggataga actgacgaag
    23701 tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccatacct
    23761 acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt attttttacc
    23821 tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg atacgatgtg
    23881 ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt ctgccttgcg
    23941 tttttcaagt tcttcttcgg atacagccat ggaaatttct ttggtatctt ggtcaaccgt
    24001 aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt caggagctat
    24061 atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca agagggccac
    24121 cttatctccc tgacctttac caacaatcat tgaagaaagt gatagcatct caggcatacc
    24181 aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa cgatttcatc
    24241 tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg gtccaacgtg
    24301 acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa ggttcccgtt
    24361 caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga taactttttg
    24421 gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac cagtacatgt
    24481 gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg cagggacacc
    24541 accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt cggccaagtg
    24601 aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat ttgcggcatg
    24661 ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca tcgttacagt
    24721 aatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac caagttccaa
    24781 catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag ctgattcagc
    24841 tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag ttgccatggt
    24901 attagcagta tacataccac cacaaccacc agggccaggg caggcattac attcaagacg
    24961 tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt caaagacaga
    25021 aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac cataggcgaa
    25081 aatagctggg atatccatat tagcaatagc aatcatagat ccaggcatgt tcttgtcaca
    25141 gccaccgata gcgacgaagg catccacgtt gtgaccactc atagccgcct cgatggagtc
    25201 cgcgatgatg tcacgagatg ttagagagaa acgcatacca ggcgttccca tagcgatccc
    25261 gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt tgacaccttc
    25321 tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt ccgcccaagt
    25381 cgaaatcact cccacaatcg atgtttcaaa gtccttatct gtcataccag tcgcacgaag
    25441 catagcacgg ttaggtgatt taaccatgct gtcatagatg ctactgcggt gacgtttatc
    25501 taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca attttcgcat
    25561 gaagaacaga ataaaaatct tgaattttca gaaaattcta tacacatgtg aaatatttaa
    25621 aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg ctttttaatc
    25681 cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcagata agtgtattta
    25741 acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat tcactcaaac
    25801 catactcatt aagaagataa tccattttcc ctacttgacc gaatctttct tgaacaccca
    25861 tccgatgaat ttttgttatt ccatcatcag agaataattc acataaagca ctgccaattc
    25921 cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac attgttttta
    25981 tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa taacctaatt
    26041 tagacagttc atctgcaact cgaatacttg gagcaaccat tataccagaa gcaacgatta
    26101 caagatcttc cccatgtctt aactcaatgt agcctttaga aaaatcttct ccaccttgat
    26161 acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt aagtctaatg
    26221 tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg gtcgatttag
    26281 gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca ttcatttctg
    26341 cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat ccaagagaaa
    26401 taaataattg atcaaatacc cttcgtgaag caaaaggacc aaatgtatga agataaggtc
    26461 taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc ataatcccaa
    26521 cattcacata acggtctcca aagttctttt caagattatg agtagccatc gaacttgaca
    26581 aatcggcttc taagactact atatcagaat aactttgatt agcctctaaa aggaagtctc
    26641 tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca attcctgact
    26701 taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc gaagatgatg
    26761 attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat ctaatacaat
    26821 gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat aaatttctct
    26881 aatatctgaa cccttgaccc taatggattc aaatccaaat gctgaaaatt tttctacgaa
    26941 atcacctgga ttacaaatat cctttgtaaa accatctaat tgttttttgt tatcatcaac
    27001 aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct cccaacattg
    27061 tccctcattt aactcaccat ctccaacaat agcataagta taaaagggac tctttcttat
    27121 tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag agcccgttgt
    27181 catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg ttccatttgt
    27241 atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg tactgtatag
    27301 agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg ctgcaaatat
    27361 ttctggagtc attggcatta tttcaccata aagcactgct aaaacttcta cgatagacag
    27421 acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat ttaatcggat
    27481 gttagtcgca aattttctta actcatcttc tctattttca cttaaaatca tcccttactc
    27541 ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta gaataagaac
    27601 aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta aaataattcc
    27661 tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc ctcccaaaac
    27721 tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg ctccaatagt
    27781 ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc cacagaagaa
    27841 atgaggcaca acacctggta agataacaac cgttcctgaa gcaatcataa ttgccatact
    27901 tactaaacca ccaataaaac tagagataaa tccaattaga actgcattgg gtgcataagt
    27961 ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct ctgaaatacc
    28021 tttaaaggct ggaacaattt cacccaaaat aaggcgaaca cctgctaaaa taacaaatac
    28081 ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg taccactact
    28141 gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt aaataactgc
    28201 catagataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct ttggaaattt
    28261 aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac cactcaacca
    28321 atatcccaaa gaactgaaat gacctaaagc caccttgtca tttccagtta attgaaccat
    28381 atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta atcctcctag
    28441 taagatgaga ggcaagctag taaagccagc aactgataaa atgaccgcaa ttatacatgc
    28501 catatataga gtgtggtgcc ctgttaaaaa gatatattta aatcgagtaa aacgagcgat
    28561 taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc catatgttgt
    28621 taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat gaaaagcatg
    28681 ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac caccagatac
    28741 aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta atttcttctt
    28801 ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg tactaacaat
    28861 atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt cttcacaaag
    28921 tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga tacgaacatc
    28981 tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat cagcagcatt
    29041 tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat tcaaatcact
    29101 caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg aaccacaagc
    29161 tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa tgtcatcata
    29221 gttttttgat gaaattaaag tttgaacatg atttttatct cttaaaattg ttgttaaatg
    29281 tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca acaatcttac
    29341 ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca ttgacattcc
    29401 tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct tccctaaatt
    29461 aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt tctccgttat
    29521 cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc atcctaattt
    29581 ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg gtacaatttc
    29641 ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt ccaattcttg
    29701 tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa aatctccata
    29761 ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt gctcttcagt
    29821 catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg tagaaaaaac
    29881 catatcatag tcactactag ctttcacctg taaatcatca atctttgagg ttcctataaa
    29941 ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag aactaacacc
    30001 attaggacaa atgattgctg ctttatacca tttttgaggc aaagtatctg ctttctttaa
    30061 ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg gattgtcaat
    30121 agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag gataatgttc
    30181 tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc tatagtaagc
    30241 cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa aatgtaacaa
    30301 agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt aaaccggagc
    30361 aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc gataatcatc
    30421 ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata aaatagtggt
    30481 tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt caacatccct
    30541 ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt gattaacaat
    30601 aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca aatcataagt
    30661 taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta tggaggattc
    30721 cagcaactca ctaaccattt gaaaagctaa acggtgctta ttccactctg aaccgtgtaa
    30781 agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca taatctttct
    30841 taatgattga atatcagtta aggttgtatt cttacttact ttcaaaaagt cttggtaatg
    30901 attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag ctaagcgagt
    30961 cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact gcttcgtacg
    31021 atttgataaa ctatagcgac cttgtttttt atccagcact atccctttat tagctagata
    31081 aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca ccttaacaga
    31141 taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa ctagtgctct
    31201 ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaaatt ataagaataa
    31261 aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg ctgaaagttt
    31321 ttagtgatta tttttcaact ttctattgac tttataaatt aaagtgatat catttagata
    31381 tcaaataaca ggaggtcatt cttatgactg aaaaactaat caattcaaaa ccaaatggtg
    31441 tattcgcatt gattctcatt gagttgacaa tcgtacttgg tatctttata tttataatgg
    31501 gggttggttc ggaaaacatt tttggaatta ttatcggacc tttactaatc gtaattgcag
    31561 gtctagctca tgctggttta aaagttgtca aacctcagga agctctggtt ctgacactct
    31621 ttggtaatta tacaggtacc atcaaagaac ctggttttta ctttgtcaat cccttcagcg
    31681 tagcagtcaa ccctgcaaac cacactcgac ttggacaaag tggtgatgtt agcacaaaat
    31741 ctcctttttt aggagctaaa tcatcaaatg gcaatgatgt aaatcttgaa attggcaaga
    31801 aacacatttc cctcaaagtc atgaccttga gcaattctcg tcaaaaaatc aatgattgct
    31861 taggaaaccc tgtagaaatc ggtatcgcgg taacttggag agttgtcgat accgctaagg
    31921 cagtcttcaa cgttgataac tacaaagaat atctttcatt gcaatgtgat agcgccctcc
    31981 gtaatattgt ccgcatctat ccttacgatg tgtctcctaa tgtggatact acgggtgacg
    32041 ggcaagcaga tgaaggtagt ctccgtggct ctagtgaaat tgtagctaac cgtattcgtg
    32101 aagaaatcca aagtcgtgtt gaggatgctg gcttggaaat ccttgaagca cgtatcactt
    32161 acctagctta tgctccagaa attgctgccg ttatgcttca acgccaacaa gcatctgcca
    32221 ttattgatgc acggaagatg attgtagatg gtgctgtagg aatggttgaa atggcactag
    32281 aacggctcaa tgaaggggaa ttggtagaac ttgacgaaga acgaaaagct gccatggttt
    32341 caaatctcct tgtcgttctt tgtggcaatc atgatgcaca accaattgtc aacacaggaa
    32401 gtctttacta aagatggctg aagctaaaaa aaagcagatc ccccttcgac tctcaacaaa
    32461 gttatacgct gcactcgcat catgggcaga agacgacttt cgttcagtca atgggcaaat
    32521 cgaatatctc ctcacagagt gtgtcaagca acggaaaaaa gacggaaaat acgtatcaga
    32581 aaccattgac gaaccatttg agattgatat ttaacacctt ctcctgtctg ccgtgtcgga
    32641 taggagaatt ttttcatctt tttttgtcaa gtaactttac tttacaaaaa aaatgtgtta
    32701 tcctagtatg gttgatgaaa atcagtagat tgaatcgaat ataaatacct aaaggagaaa
    32761 tcaaaatggc agtacctgca cgtcgcactt caaaagcgaa gaaaaacaaa cgtcgtacac
    32821 actacaaagt aacagctcca tctgtaaact ttgacgaaac tactggagat tactcacgtt
    32881 ctcaccgtgt atcacttaaa ggatactaca aaggacgtaa aatcgctaaa gctgcatcag
    32941 ctgaataata gaagggagat accatgcgcg taaatattac acttgaacac aaagaatctg
    33001 gtgaacgctt gtaccttact tctaaaaaca aacgtaacac tccagaccgc cttcaattga
    33061 agaaatactc accaaaactt cgcaaacacg ttgtgtttac agaagtgaag taagcattca
    33121 atacgaatca atacagaaga aaaacgcttg atcagcgttt tttctttttg ttaatttcac
    33181 tatattgcaa gagaaatcat tcgaatgact acattttttg aaataagaat acggattcgg
    33241 acgattaaaa gtaagagaaa ctcaaatgta agttggggtt ccttttttgt atatttttca
    33301 aataacgcct ctacactatt tgtagcaaat tcaccaacta cagttgcatc ttagttaaaa
    33361 taagttagaa tatgtaagtg agtaccagat ataccaagac atcgtcacca tctaaggtat
    33421 attcaaaata caaaagttga ccaactagat ttctgaatat ccttatatat ccattcttaa
    33481 aattggttta aatagcgtag tcttttaaac tagttttgag aatccaaaaa atcttcctac
    33541 atatgtaaga agatttttta gttcagaatg attagattta gctaatggat acctatccta
    33601 cccactcacc gttagcattg actcgatagc catcgggtgt agtcgtgttt actaataaat
    33661 ctcctgaatt ataggtatag taccatttac cagaaactgt aa
//
LOCUS       DAVKXA010000019        33585 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKXA010000019 DAVKXA010000000
VERSION     DAVKXA010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33585
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.019"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(237..599)
                     /locus_tag="VW883_000977"
     CDS             complement(237..599)
                     /locus_tag="VW883_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0274137.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVDHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSTVSAIDSSEAMLL
                     PIINVLELLDKSQPFEEE"
     gene            613..687
                     /locus_tag="VW883_000978"
                     /pseudo
     CDS             613..687
                     /locus_tag="VW883_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(914..1072)
                     /locus_tag="VW883_000979"
                     /pseudo
     CDS             complement(914..1072)
                     /locus_tag="VW883_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1345..2034)
                     /gene="rplA"
                     /locus_tag="VW883_000980"
     CDS             complement(1345..2034)
                     /gene="rplA"
                     /locus_tag="VW883_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0274138.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2242..2667)
                     /gene="rplK"
                     /locus_tag="VW883_000981"
     CDS             complement(2242..2667)
                     /gene="rplK"
                     /locus_tag="VW883_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0274139.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2790..3506)
                     /locus_tag="VW883_000982"
     CDS             complement(2790..3506)
                     /locus_tag="VW883_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0274140.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3524..3985)
                     /locus_tag="VW883_000983"
     CDS             complement(3524..3985)
                     /locus_tag="VW883_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0274141.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3987..5024)
                     /locus_tag="VW883_000984"
     CDS             complement(3987..5024)
                     /locus_tag="VW883_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0274142.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5122..6447)
                     /gene="brnQ"
                     /locus_tag="VW883_000985"
     CDS             complement(5122..6447)
                     /gene="brnQ"
                     /locus_tag="VW883_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0274143.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6618..6710)
                     /locus_tag="VW883_000986"
     CDS             complement(6618..6710)
                     /locus_tag="VW883_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0274144.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6753..6905)
                     /locus_tag="VW883_000987"
     CDS             complement(6753..6905)
                     /locus_tag="VW883_000987"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0274145.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7034..7111)
                     /locus_tag="VW883_000988"
                     /pseudo
     CDS             complement(7034..7111)
                     /locus_tag="VW883_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(7112..7690)
                     /locus_tag="VW883_000989"
     CDS             complement(7112..7690)
                     /locus_tag="VW883_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0274146.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7744..9144)
                     /gene="pepV"
                     /locus_tag="VW883_000990"
     CDS             complement(7744..9144)
                     /gene="pepV"
                     /locus_tag="VW883_000990"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0274147.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTVP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKIRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9157..9762)
                     /locus_tag="VW883_000991"
     CDS             complement(9157..9762)
                     /locus_tag="VW883_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0274148.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9933..10733
                     /locus_tag="VW883_000992"
     CDS             9933..10733
                     /locus_tag="VW883_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0274149.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINHWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10911..11744)
                     /locus_tag="VW883_000993"
     CDS             complement(10911..11744)
                     /locus_tag="VW883_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0274150.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNILFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11734..13578)
                     /gene="uvrC"
                     /locus_tag="VW883_000994"
     CDS             complement(11734..13578)
                     /gene="uvrC"
                     /locus_tag="VW883_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0274151.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13618..14319)
                     /locus_tag="VW883_000995"
     CDS             complement(13618..14319)
                     /locus_tag="VW883_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0274152.1"
                     /translation="MRWLFRLIGAFFFFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14398..15630)
                     /gene="murN"
                     /locus_tag="VW883_000996"
     CDS             complement(14398..15630)
                     /gene="murN"
                     /locus_tag="VW883_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0274153.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTIGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15635..16855)
                     /gene="murM"
                     /locus_tag="VW883_000997"
     CDS             complement(15635..16855)
                     /gene="murM"
                     /locus_tag="VW883_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0274154.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16967..17746)
                     /locus_tag="VW883_000998"
     CDS             complement(16967..17746)
                     /locus_tag="VW883_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0274155.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKCEKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLVVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17815..19476)
                     /locus_tag="VW883_000999"
     CDS             complement(17815..19476)
                     /locus_tag="VW883_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0274156.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19651..21873)
                     /gene="recJ"
                     /locus_tag="VW883_001000"
     CDS             complement(19651..21873)
                     /gene="recJ"
                     /locus_tag="VW883_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0274157.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFITFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDLPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22150..22908
                     /locus_tag="VW883_001001"
     CDS             22150..22908
                     /locus_tag="VW883_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0274158.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22948..23712
                     /locus_tag="VW883_001002"
     CDS             22948..23712
                     /locus_tag="VW883_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0274159.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23725..24402
                     /locus_tag="VW883_001003"
     CDS             23725..24402
                     /locus_tag="VW883_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0274160.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPFYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPGFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24412..25071
                     /locus_tag="VW883_001004"
     CDS             24412..25071
                     /locus_tag="VW883_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0274161.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEVGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25320..26510
                     /locus_tag="VW883_001005"
     CDS             25320..26510
                     /locus_tag="VW883_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0274162.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKIIHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26831..27712)
                     /locus_tag="VW883_001006"
     CDS             complement(26831..27712)
                     /locus_tag="VW883_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0274163.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27853..29181)
                     /gene="vncS"
                     /locus_tag="VW883_001007"
     CDS             complement(27853..29181)
                     /gene="vncS"
                     /locus_tag="VW883_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0274164.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENSLTFFIDFPKVVQD"
     gene            complement(29178..29834)
                     /gene="vncR"
                     /locus_tag="VW883_001008"
     CDS             complement(29178..29834)
                     /gene="vncR"
                     /locus_tag="VW883_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0274165.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKATKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29883..29966)
                     /gene="pep27"
                     /locus_tag="VW883_001009"
     CDS             complement(29883..29966)
                     /gene="pep27"
                     /locus_tag="VW883_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0274166.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(30146..31525)
                     /gene="vex3"
                     /locus_tag="VW883_001010"
     CDS             complement(30146..31525)
                     /gene="vex3"
                     /locus_tag="VW883_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0274167.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31577..32224)
                     /gene="vex2"
                     /locus_tag="VW883_001011"
     CDS             complement(31577..32224)
                     /gene="vex2"
                     /locus_tag="VW883_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0274168.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32237..33514)
                     /locus_tag="VW883_001012"
     CDS             complement(32237..33514)
                     /locus_tag="VW883_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274169.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKGSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVTLCFLFLFRKSPKEILSSIS"
BASE COUNT         9552 a         7684 c         6204 g        10145 t
ORIGIN      
        1 cagtctacta tacataaact aacctcctca ttattagcaa ggcttctact gattataacc
       61 taattcttag actacttcaa gactaactgt ccaataataa tctacagata aatcatccac
      121 tcttaatcaa attttattca atccatctac tcattcccaa aaggttgctg tataatgcaa
      181 gacatttttc ttactgcttt tacttttcct taccctcaat ttagtgagct aataaattat
      241 tcttcttcaa aaggttgaga tttatctagt aactctaaaa cattaatgat aggtagcaac
      301 attgcttcac tgctatcaat tgccgaaact gttgaaacaa tagaacgtaa ataaggataa
      361 agaatagcag taccatttac gtatagaata tcggtgatat tttcatctat atttatttca
      421 aaatatccta ttacagttac agatattttt ttcatggcat ctttgtcaac taaagaaaca
      481 ctaagtttta cggctccatg actataatca tctgtatgat caaccttaac tatgggatat
      541 aatatatcga aggtaaatgt gaacaaactg attaggaaat ttaaaccaac ttctaacaat
      601 ctgttatact caatgaaaac caaagagcaa actaggaaac tagcctcagg ttgctcaaaa
      661 cactgttttg aggttgtaga tggaactgac gtagtcagct caaaacactg ttttgaggtt
      721 gtggatagaa ctgacgaagt cagtaaccat acgcacggca aggcgacgtt gacgtggttt
      781 gaagagattt tcaaagagta ttagaaagct cgatggacta ttccagattc attccactag
      841 atttcgaaat cgagtagggg ataatctcta gcccctctca caccaccgta cgtgccgttc
      901 ggcatacggc ggttcaacta actgttaacg catgtcgttc aaggtaataa tccaaacacg
      961 aaaccagtcc acgtttttca aggactgatt ttgatatagc acgtttaagt accgactttt
     1021 gagctactaa ttgatagtgg tcgccccagc cagatacctt atccgctata tacgccttat
     1081 tatcacgttc ctgttcgtag agccacgatt tcgctatccc ttcctctgac gattcttatt
     1141 tccagcgtca gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata
     1201 gtcagacttg ggaatcgcta ttgggttcac cggtagcagg tgcccaccga ggatttacac
     1261 ctcagatata cgacatgccc gtcgtacatc aaaaaaagtt gagacatagc gtcttcaact
     1321 tttttacatt actttaacta ctgattaaag tgagtttacg tcaactttga taccaacacc
     1381 ttgagtagtt gtgatagtca agtttgttac gtaagttcct ttagctgtag ctggttttgc
     1441 tttttggatt gtttcgttga aagctttaaa gttttcaacc aatttttcag cttcaaatga
     1501 tactttaccg atgattgctt gaacgttacc tgcacggtca gcacggtaag tgattttacc
     1561 acctttagac tcttcaactg ctttagcaac atccattgtt acagtaccag ttttagggtt
     1621 tggcatcaag ttacgtggtc caaggacacg tccaagacgt ccaacaagag ccatcatatc
     1681 aggtgtagcg ataactacgt cgaagtccaa ccaaccgtcg ttgattttag caacaaggtc
     1741 atcttcacca acaaagtctg caccagcagc ttttgcttct tcagcttttg caccacgtgc
     1801 gaaaacaaga acacgtgaag ttttaccagt accgtttggc aataccattg ctccacggat
     1861 ttgttggtca gcttttttaa cgtcgatgtt caagttgtaa gcaacttcta cagttgcatc
     1921 aaattttgca aagttagttt cttttgcaag tgctacagct tcttctacac tgtatgcttt
     1981 tgtgctgtcg attttctcaa gagcagcacg aagttgtttg ctttttttag ccattttcta
     2041 ttctccttgt aagtggttca atcgattttc atctcccacg tcacttctcg aaatgatgaa
     2101 gtcttgcggg ttttcagtct actatttttc tcttcctacg gccttaagct cccttgctgt
     2161 acccaagtac aaggctcagt cacttgccta gtatgaaaag caactaatag actgctgtga
     2221 gattttctac tgtgttattg attagtcaac aacagtgaat cccatagaac gagcagtacc
     2281 ttcgatcata cgcattgcag actctacgtt tgctgcgttc aaatctggca tcttagtttc
     2341 tgcaatttct tgtacttgtg cacgagtaac tgtagcaact ttagttttat taggtgtacc
     2401 tgatcctttt tcaacacctg cagctttttt caaaagaaca gcagctggtg gtgttttcgt
     2461 aacgaaagta aatgatttat cttcgtaaac tgagataaca actggaatga tcataccagc
     2521 ttggtcagct gtacgagcgt tgaactcttt tgtgaatccc atgatgttga taccagcttg
     2581 accaagagca ggtccaaccg gtggagctgg tgtagcttta ccagcaggga tttgcaattt
     2641 tacaagtttt tcgacttttt tagccatttt taaatcctcc tttgtggttt tggcggtaat
     2701 tagagatttt tacctcccac aagtatgttt ttcacatacc catccattat acactattta
     2761 tctggaattg caagagaaaa ctttcatttt taatcgacat aatcgccgcc ttcaaagcca
     2821 tagtactctt ccaaactgag accacttgca gcaatttctt tggcttcttt tccaacgtag
     2881 cggagatgcc attcttctgc catgtagcca gtctcctttt ccttgccttt aagatagcga
     2941 acaacaaagc catagtcagc cgcatggtcc aagagccact gggctgcctt ttcttcagta
     3001 actaaatccc catctgtccc aatcaaatca aaagcaagac ccgtctggtg ttcactgtaa
     3061 cctgggcgtg ctgagtagcg atctgctgct tccttaccat cttgattgac atagtcttgg
     3121 tagagcttag cctgagtttc ataactccta aacccactgt attggtcact gattggatag
     3181 ccctcagcct gcatagctgc gattagtttg agcaactctg ccttggctgt tggattttct
     3241 cctggattgt aatcttttga caaaggataa cgtttattag ctaggataat ctcatcgtat
     3301 ttcccttgga tactataata gctcccttta ttgctaactt ctgccttttt ctgactagaa
     3361 gcttgagatt tgctacctac agttccttcc ggttgactgc tttgctccgt tttttgagtg
     3421 ttttcttcaa ctttggtttt ttcttgcgaa caagctgcaa gggtcaatgc tagtaaacca
     3481 gataaaatga catatctttt tttcatttct ttcttcctct ctcttaggcc aaatacttct
     3541 ccaattcatg agataagatt ttaatcatct cttccagctc tggcgattgt acttggcaat
     3601 cttctgccgc catttcttcc cagggcaccc accagactgg gccacggcca ttcaaaccgt
     3661 gactcttcat atcacctgct cttcggggaa aaagatgcca atgagcgtgg gcatcgccat
     3721 ttcctaggag ttcaatattc atcttttcag cctcaaatgc tttggcgact gcttcttgga
     3781 ctaaactcat ttcctctaaa aagcgaagtt ttacagaagt ttccatatga tggagttctg
     3841 tgacatgatc ttttgctaaa aataaggtat agcccttaaa gtattggtag tcaccaataa
     3901 caacatagcc tgtttctagt tcttttacaa agtagggatt ttgcccagct ttaatgagtt
     3961 cgattctctg acagattaag cacattctat gataccgcct cgctcttaag ataagcatca
     4021 accatacgct cagtcgctac tactgaatcg atgtgggtgc gctcataaga gtgactggac
     4081 tcaataccag ctccaagaag tgcatgcttg acctctgcac ctgctgacat cgctgctgaa
     4141 gcgtccgatc cgtaaaatgg atagatgtcg agcttaaatg gaatatcttg ctctttagcc
     4201 aaggcaacca agtgttgacg gaagtcatag tgataaggac ctgaagcatc cttgacacag
     4261 atagatactg tgtactcatc tgtctgctgg tcatctccca tagctcccat atccacagcc
     4321 agatattcta ctacctgagc aggaatgtta gaattagcac catgtcctac ttcttcaaaa
     4381 actgaaaaag caaaatgagt tgttactggc aattcaatct tctctttctt ataaatacga
     4441 agcaggttga gcaaaatcgc tgcgctgacc ttatcatcca aatgacgaga cttgataaaa
     4501 cctgtatcag tcacaacagt tcgtggatcg aagctgataa aatcaccgac ctcaatccca
     4561 agagcacgag tttctttttc attgcttact tttacatcca aacgcacttc catattgtcc
     4621 tgcgtgcgtt ctgcagttcc tgcatccttg tagacatggc aagaagtttg gtggatgagg
     4681 atggttcctg ataccttttg acctgtgcta gccacatgaa cggtacagtt ttcaccttca
     4741 atcatgttcc aaggaaaacc accgatacgg tccaatttaa gacgaccatc tggtttgaca
     4801 gcacgaacaa tagcacccag cgtgtccaca tgggcagtca catagcgatg ttgctcatca
     4861 ttttgacctt tgatggtcac attgacacca cccttggctg tgcgaactgg ctggtaacca
     4921 aaaccttcta gagtcttgac taaataattc gaaatttcac gagtgaagcc cgttggcgat
     4981 gcgatggctg tcagttcttt gatatattct actgtttgat tcatttcttc acctctttcg
     5041 ctacctatta taacacattt atcatcggat aaaaaaagaa aatcactcct gtagacttgg
     5101 ctacaaaagt gatttaagtg attattccat ttcaaaaaca tcgctttctt gcttgtttgg
     5161 tagaaccaat gagagcaaga ttccaacaat ggctggcacc aaccatggga gagatgcctt
     5221 ggcaaaagga agaacgctaa caagatttgc aagaaactca accttaaacg agcttcctag
     5281 tacgcttgca atggcaataa ctgtaaccac agcaattgtc aactgcatac ctggttttga
     5341 aagggcaaca aatttgttga caatgacaat cataacgata gcaatcgtga ttgggtacaa
     5401 gataaccagt actggaattg agtacttgat aatcgcatca agacccaaat tggcaatagc
     5461 aaatccaatc aaggtaaagg ctgtcgcata aaccttgtag ctgatttgtg ggaagcgctc
     5521 attaaagaac tcagctgttg acacaatcaa accaacagtc gttgtgaagc aggttacggt
     5581 aaccatagct gcaaggaaga gttgagctgt tgagccaaag atttcttgag tggcttgtga
     5641 caagatgtaa acacctggtg ttccaccctt catcgcttca gctggtactg ggaaatgatt
     5701 tccaagaaaa cctaaaccga tgtaaagagc gctgaaggca agggcaacaa cgataccaac
     5761 aacccaaata gttgaaatgt attctttctt acttgaaaat ccaagttgtt tcaaggtttg
     5821 aactgcgatt acgctaaagg ccactgaagc aagggcgtcc aaggtattgt aaccttctag
     5881 gaaacctgta ccaaaggcag aagcttgata agcagctgaa gcagcttgag gacttgttcc
     5941 accatatttg atagctccca gaacgaccaa gataacaatc aaaattgcaa agactggcgt
     6001 taaaatacgt ccaatgcggt ctaagatttt tgatggatta agcgaaatca aataggctgc
     6061 cgcaaaatac agaaccgtaa atacaatcaa gccaagtcct ttatttgcat ccgacaaaag
     6121 ggggctaatc cctacttcgt aagctgttgt agcagtacgt ggggtagcaa agaatggacc
     6181 gattgacaag taaagaactg agaggtaaag agtcgcaaac caaggcgcta tcttcgttga
     6241 aatctcgtag atatatcctt taggatttag cgttccaata ataagggtca agacggcgat
     6301 accaacgcct gaaaagacaa aacctgcgat ggcaggaaga aaatgttctc cagatagagc
     6361 acctagagaa ggcggaaaaa tcaagttccc cgcaccaaaa aatattccaa acaggagcaa
     6421 acctgttagg gtaccttttt tagccataaa aatctccttc atatttataa aatactgacc
     6481 tagtatacca cgattaggag tctgaaaaaa gcatcacgag gcaaatatta aatgttttca
     6541 attttcttaa aaataagaat tatctaaaaa taaaactctc ctactcagtc cacaccaagt
     6601 aggagaaatg caaaatttta aagttcttca aaggctaaca tgccaccctg gacattgata
     6661 acattataac cttgttctaa taggaattgg caagcacgcg ccgatctcat tccagatttg
     6721 caaataatat aatgcaagcg atctttgtcc aattaatcat aactatcagc caattgacta
     6781 agcggtaggt tgtgggcacc ttctaaatga agagctgcaa actcatccac ttctctcaca
     6841 tccactaaag aaagctggtc gttttggtaa agctggtaaa atgcgtcaaa ggctatttct
     6901 ttcattcttt ttcttctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt
     6961 accgtgcgta tatgtaactg acttcgtcag ttttatctgc aacctcaaag cagtgctttg
     7021 agctgacttc gtcagttcca tccacaacct caaagctgta ctttgagcag cctacgacta
     7081 gcttcctagt ttgctctttg attttcattg actataaaat ggttttaatt ctttttttca
     7141 aatctggcac tacttctgcc tcaaaccaag gatttttggc catccagatt tgatttcgtg
     7201 gtgatgggtg aactagcgga aaataggctg gcagatagtc tttatagtgt ttcaccctct
     7261 ccgttacctt cccactgatt ttctcctgta aatagtaggc ttgggcatat tgcccaatca
     7321 agagggttaa ctgaatatca ggcaattcct gtaagagctg cggatgccat ttttctgcaa
     7381 aacctgtacg aggcggaaga tcacccgact tgccatgtcc tggaaagtag aaatccatag
     7441 gcaaaacagc aaaataacct gaattgtaaa aggtatcttc atccacacct agccagtccc
     7501 gcaagcggtc accactttta tctttccagt aaaggcctgc ttcttgagtt ttaagtcccg
     7561 gagcctgacc gatgatattg atgcgagcag tttttggcgc tgcaaagaga ggctcaatgc
     7621 cacgctctgt atagctggca ttctgtgaat ccgccatgat agcctgtttg attctttcga
     7681 tttgagacat ctactttccc tccaaaaaga agtccaagca taagatctca gacttctatc
     7741 gttttatttg atcaattcgt aaatagcttc ggcataaatt gctgctgctc ggaaaagatc
     7801 atccaaggcg ataaattcat tggcttggtg catggtatca atcgagtctg ggaacatagc
     7861 accgtaggca actccgcgtt ctagcaagcg accaaaggtt ccaccaccga tgacttgttc
     7921 atgaccttta aggccagttt gtttttcata gacattcaac aaggtttgca caagtggatc
     7981 ttccattggc acatagtgag gcgtgtgacc gtgttcagac aggctaacag aaacaactgg
     8041 caagttttca aggattgact tgatttgttc tggacttgtt ccttttggat agcggatgtt
     8101 gagggcaatg gtattatcag cacttgtttc atcgaagcgg aagacgccgg cattcataga
     8161 aagagcaccc atcttttcat ccacatgagc aatcttaaga ttttcaccct catgatcgtt
     8221 caagagaatt ttacctgcga tgtcaaggta atctttggct ggaccagcaa agccaaactg
     8281 gctgaggaag agggcaaggt aagttgcgcc attgacacct gaagcaggca tagcaccgtg
     8341 ggctgattta ccaatgatcg tcaccttgta tttgccagct tcttcttgga gttctcctct
     8401 aagtttgtgt tctgcaacaa aggcatctag tttagcttgc aagtcagcca aatcacctga
     8461 aacgactgct gttgctgatt ctggtaccat attttcacgt aaaccacctg taaagctgtg
     8521 aagacgggca gcacctgtat tttctcctgc aaagtggagg tattccgtga tatttccttt
     8581 ttcaccattg atgattggaa attcagcatc tggtgagaaa ccgaaatctg gtttggcaag
     8641 tcctacgtgc tcaaagtagt agtccatgtc tgcccagcct gattcttcgt ctgttccaac
     8701 gatgaagcga attttcttag aagttggaag acccaattct ttgatgattt tcaaaccata
     8761 gtaacaagct gttgtaggac ccttatcgtc cgaagccccg cgcgcataaa ggcgaccatc
     8821 tttgatagtt ggtgtgtaag gaactgtatc ccaaccgcta ccagctggaa ccacgtccat
     8881 atgggcaaag attccgagaa cttcttctcc atcaccaaac tcaaaatgtc ctgcgtagtt
     8941 atcgacattc ttagttgggt agccatcgcg gtctgcgatt tcaaggaatt tctccaaggc
     9001 ttttactgga ccaggtccaa atggatgctg ggcatcagcc ttgctatcat cacgttctga
     9061 gttgatttcc aaaaggctaa acaagtcagc caagaggtct tctttgcgtt tttctacttc
     9121 tgctgtaaaa tcaattgctg tcattttttc ttctttctat cttttctcga tgatttcatc
     9181 tactggcaag cggtagcttg gttccaattt ttcgtctgta taacccactg tgatcaagag
     9241 ttctgggcgg aaacggtctt cgatttccaa aacttcatta acttttgatt tgtcaaaacc
     9301 aagaataatg ttagaaccaa ttccttggtc tgtcaatgca agaaccaagt tcatggcaac
     9361 caaacctgca ttgagagcta ggtagtcgct gacttgttgc tcattgtaac gggcaaactc
     9421 agctggcaaa tttttcatga agtattgaag ttgttcttct gagaaattgt tagcaccacc
     9481 aactcgggca atcttacgag cgcgtttggc aaggtctgta tctgtaaata gggcaatggt
     9541 tacaggtgct gatgatacct gctcaaagtt tgaaccataa gccaactttg ccagttcagc
     9601 atttttctca cgaacaacta caaatttcca aggctggctg ttgtgggcgc ttggcgccaa
     9661 ggttgcaatt tcgatagccg tacgcacatc ttttggatca acaggcttat cagtaaaatg
     9721 cttagtcgca tgacgttttt tatttaattc aagaaatttc ataatcgatt tccttttcta
     9781 attctactgc ttccattcta ccataatttg aaagagcttg cagggatttt tcatgattaa
     9841 gtttttctat cacagacata aaagatatat attggtttat caggaaagtt tctgataaac
     9901 tagcaagtac tttacatttg aatggagaca gtatgaaaaa atttagccta ttactagcta
     9961 tcctaccatt tttggttgcc tgtgggaatc aagctacacc caaagagact agcgctcaaa
    10021 agacaatcgt ccttgctaca gctggcgacg tgccaccatt tgactacgaa gataaaggca
    10081 atctgacagg cttcgatatc gaagttctaa aggcagtaga tgaaaaactc agcgactacg
    10141 agattcaatt tcaaagaacc gcctgggaaa gtatcttccc aggacttgat tctggtcact
    10201 atcaggctgc ggccaataac ttgagttaca caaaagagcg cgctgaaaaa tacctctact
    10261 cacttccgat ttccaacaat cccctcgttc tcgtcagcaa caagaaaaat cctttgactt
    10321 ctcttgacca gatcgctggt aaaacaacac aagaggatac cggaacttct aacgctcaat
    10381 tcatcaatca ctggaatcag aaacacactg ataatcccgc tacaattgat ttttctggtg
    10441 aggatattgg taaacgaatc ctagaccttg ctaacggaga gtttgatttc ctagtttttg
    10501 acaaggtatc cgttcaaaag attatcaagg accgtggttt agacctctca gtcgttgatt
    10561 taccttctgc agatagcccc agcaattata tcattttctc aagcgaccaa aaagagttta
    10621 aagagaaatt tgataaagcg ctcaaagaac tctatcaaga cggaaccctt gaaaaactca
    10681 gcaataccta tctaggtggt tcttacctcc cagatcaatc tcagttacaa taatactctt
    10741 cgaaaatctc ttcaaaccac gtcagcttta tctgcaacct caaagctgtg ctttgagcaa
    10801 cctacggcta gcttcctagt ttgctctttg attttcattg agtataagat atataaaagc
    10861 gattggacta ccaatcgttt ttagtttgca ttggttattt taggaaactc ttacaaaaaa
    10921 tcaaaaaaat tcttcacatc ctctacatac ccatgctttt ctattaagct tgctaataat
    10981 tccagattgt gcccctgata gttatcgtca cgacgcagtt cttcatacat ttcgataaag
    11041 ggaagtccct tggacttggc caattctaac tcagcctcgt aatcataagc aactttacga
    11101 aataggatat ttaccaattc cccatcttca acctctatca cggcatactg ggcacggtga
    11161 ttttttaacg cctcccaatt aaaatagggc atgccaatcg accctggatt gatgatttgt
    11221 tgcccttgac taccataacg aagcaactgc ttgtgaacat gaccataaac tgccacgtcc
    11281 gtttccgcat ctagcagttg gtcaaatttc tctgtatcat tctcaactag caagtcacca
    11341 ccatagtttt tgtcaggtaa attatgagag atagaaaagc gcaatccgtc aatttctttc
    11401 ttttccagca aaggcaagct tcgtagccag acaatcgttg caggatccat tcgctccatc
    11461 aaaaactggg tcatgcgcat tgactggatt tctttcggat attccaaacc atattcgcca
    11521 tccaagacct caaggacacg atcatcccaa ttgcctcgaa cacttgctgt gataggaagg
    11581 tcctttagca gggcgactaa gtcatttgcg cctggaccag gaagaaaaat atctcccaga
    11641 agccaatatt cactggcccc ttgattttta gcatctgcaa tcactgcttc tagcgccgtc
    11701 gcattgccat gaacatctga taaaattgcg attttatggt tcattgtggt ttccttccgt
    11761 ttggtaatct actctttctt ctgctacttg aggcaaggct tctccctgcg ggttcaactt
    11821 tctttgcaca gcctctgcaa cgactctagg taccccaact tcgacaatct catccacact
    11881 ggcttccttg attttggtca aagacttgaa atgcttcata agattctgct tgcgtttagg
    11941 tcccagaccg tcaatcccat ccaattgaga tgagaaagaa tttttggagc gcagttggcg
    12001 gtggaaagtg atagcaaagc ggtgcacctc atcttggatg cgttggagga ggaaaaattc
    12061 ctgagaattg cgagacaagt ccaccacctc aagcggatct ccaaagagca attcatgggt
    12121 ttggtgctta tcattctttt gcagcccagc aattggaata tccaagccca gttcctcttg
    12181 gataacctgc ttagcgatat tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg
    12241 aggagtcaaa gcctcacgct gtactcgacc atagcgtctg cgaatgacct ctctcatgct
    12301 ggcatagtcg tctggtccaa caaccgtttt tatcttgtac ttacggtaat ccttcttact
    12361 cggtttaccg ttgacaaaga ccaccatagc cgaaacaggg ctagttccca tgatattaga
    12421 gttatcgaag gactcgatac gtactggggt cgggatttgg agcaaacgcc ctagattttc
    12481 aatagctcct tgagtctttt cgacagattt ttctagcagg ttaaatttct gctccagact
    12541 aacacgtgca ttttttatgg ctagattgac cagttgtttt ttctctccac gttgaggctt
    12601 aagaatcttg gaatccacca aggccttgac agcctcttcg tcaatatcct gcggaatcag
    12661 tacctcattg ggaactagat gagatttttc ttgatagaat tgtcctacat aggtcaaaaa
    12721 atcctcatct ggatcattga agtaggggaa gagattgaca tcgcgctcga taagcttacc
    12781 ctgacggaca aagaaaacct gcacacacat ccagccctta tccacatagt agccaaagac
    12841 atcgcgattt tgcaaatctt tcgccatgac ccgttgcttg gttcgaagcg ttccaatagc
    12901 ctgaatcagg tcacggtatt ccgccgcacg ttcaaactcc atactttgtg ctgctactgc
    12961 cattttactc ttgagatcat cgatgatttt gttatcctgc cctttcagaa aatcagaaac
    13021 ctcctgggcc atagacttga aataagtctc atccttctta cagatggtgt gggccatgca
    13081 ttgaccgata tggtaataaa aacagacctt agagggcggg ttggtacact tacgaaaagg
    13141 gaatatccga tccagcaacc gcttgatttc attggctgcc cccacatcgg gatagggtcc
    13201 aaaataaaga cctccgtcct ttttgacctg acgagtgata atcaagcgtg gatagcgctc
    13261 attggtgatt ttgatgaaag gataggactt gtcatccttg agcatgatat tgtacttggg
    13321 cttgttttcc ttgatcaggt tgatttctag gagaagtgcc tcaatattag actccgtaac
    13381 aataaattca aaatccacaa tttcagacac cagagcctct gtcttggtat catgacttcc
    13441 acgaaaatag gaccgtactc gattacgcag atttttagcc tttcctacat agataatggt
    13501 gccattttta tccttatgaa tgtagcaacc agggctggtc ggcaagagct ctagttttga
    13561 tttaatcaag ttgttcatag ttccattata gcaaaaaaag tagggaaaga tagtacccta
    13621 ctcactagtc tcatatattt ttcggaggtt tgcaacatcc tcttcctgga taccataaaa
    13681 ggaacctgct ggttgcatga cagacttctc atctgtatgg tccaagccaa tcgcatgacc
    13741 taactcatgt tctgccgtat ggacaaggcg ttcataggag tagccatagt atggattgga
    13801 caaataataa tgattcaacc gcaccgttac ggacaagaat tgccctgtta agagattagt
    13861 ttgactttcc gcctctcctg ccacaggagt gcctccgtcg ttcatctccg tagccgtaat
    13921 atccgcctta ctagactcag tcacgagttc aaagttaaaa gcaccagttt gattccagtt
    13981 ctggattgct tctaaataag cctcttgaaa gcgtgaatcc atctgcggat ccaggtaaat
    14041 acgagcagag gcctgtgccc accttccttc agaatgctgg tgactatctg tctggcttaa
    14101 cttaggcagt tgccctgttt tctcccattg gtcaatactt tgttgaccaa tttttactga
    14161 ccgttctgct tgctttagcg ctccttgaaa atccccgttc agataccaga gaagtccgaa
    14221 agcaagcaca cataagagca caactatcca aaccagacgc caaaacaaac gccacacaaa
    14281 aaaaaagaaa gctcctatca aacgaaaaag ccagcgcatg tctctccacc tttctagcaa
    14341 ataagaatta ttttactaaa agaagctaaa agaaatctaa atactgactt tttcatctta
    14401 acgtcctact atttttttga gtaactggat agctttgtat tttaaaggcg atggatggta
    14461 acggaaagta cccgctttgc gtacaatata gccattaaaa ttctgtttaa aacgcaaaac
    14521 accatcactt ccatcaaaaa tcccttgaat gcctaggaag ttgtatttag gtattccacg
    14581 ttttatgctt tccaacataa catatttttg aagcagggca ggggcataga acttattaaa
    14641 ctcagtgtag gaaccactaa agagataagt cgtttcctga ggcatataaa caaataaact
    14701 accagctaaa acaatatctt cttctccata tttttcaatc aagtctcgcg cttctgcttt
    14761 tcgaacttca aacgtttcaa attgactaga atattctctc agttgatttt gttttttctc
    14821 agaatgagga tttttactca aatcaagtcg caacttgtcc aagttttctt ctagtttact
    14881 ttgttcacct tgcaatttgc tcatatagtc cgaaaaattt aagcttgcta tgagaaactc
    14941 cgcttgttct ccaaaagtat cataaaaatg ctcataatat tctaaacttt tatcactata
    15001 ttctctacgt tcagaggttt cttttgttat attcttaaaa atcgatagtt cttcacgttt
    15061 taactttttc aaccgaatgc caaaggtttc agcctttttc accaagggtt tacccttttt
    15121 gctaaaactt ttaagcaaac tcttttcagt taattcagtt aaatctttat agtataacca
    15181 atctggttct ccacctgggt aacctattgt taagccatca aattgataac ctaaatcagt
    15241 caaaccttga ataatacttt ttttctcagc atctattgga ttaccttggc tatcaaaagt
    15301 ttgataagtt tcataaggtt ttacaagcaa ctctaataca ccattttgct tggcatattc
    15361 ttttaactct gcataaaaaa ctggaagagc atcttgttgg gtataaatcg gccccgaatt
    15421 gagttccata tgcagaccac ccagcatggg caagctataa accagagctg caacttgaat
    15481 ttctccttct tgtttcaaag caagataaac aattcgagcc cctctttttt ctagcaaatc
    15541 ccccatctgg acagattgca taaaggaacg agaagaaacc tgatcagaat aagtctgaaa
    15601 ctcttctttc gtgagtgttg ttagtgccat atacttactt tctatgtttt tttcttaatg
    15661 ttttacggaa atcaagagca agtcttaaca gaggatagag aggatgagtg ggcattgtaa
    15721 attcacccaa gtattcttca atcgttggat taaatttttc cttaaaatga taaagtccac
    15781 cattgagaga gttttcaaca ccacctaaat tttgccagac catacctcgc tcaaaggcat
    15841 agcgagccgt ttcataccat gttaaaattg gtgcattgta acgtttaaaa tcatcatcca
    15901 taccagcata tatattgaca gaggtagtac caaattccaa actcaaagta gccgctaaag
    15961 gaactctcgc ttgacctaca tctatatatt cctgcaagaa ggtcaattcc tctaacaaac
    16021 gttctttttc cttcttctgc gcttctactt ttgaagttcg agtcgactca gtaaacgtct
    16081 cttccaaggc tctatttttc gctaactgtt cttctaactc ttgcgaacgt ttagaaacat
    16141 ccaaggtggc caaggtgata taggccttgt ccttaaaatt atctaacaat tttttataat
    16201 aggcttcatt cctcaaatga atctcttttc gcttctcagt ttttttcatc aactccgaaa
    16261 atgaatctaa tagttccagt ccaccatatt gaatctcaag ccctttgttt cgtgctgttc
    16321 gaatagcctg ttttgttgac ttggaaagtt tatcttcttc aaaattttcc ttgtatattt
    16381 tcgcctgaat acgaggttga atggtgtctc ccatttcctc cgtttttcct gaccacctta
    16441 ctcccatttg ttgcaaacta tcaataatag ccagattttc aggaaattct gtcttttcct
    16501 gattgattaa actttgagat aggcaaatac ttgggtcaaa agtcacaaaa accgctctct
    16561 tactgcgagc ataggactta atagactgaa tggcaaaatt caagagttct ttatccccat
    16621 aatccaatat aggtcctctt gggatgtaaa acattttata gcctagcgga agagttctaa
    16681 tcaaaatact agctgtcgcc agtaattttt cttccctgta aacaccaaac ttctcatgtt
    16741 gccaattaga cttaacttcc tcccaagcac tactttgtaa tacattggct aattcatgtt
    16801 ctttgacaaa ctgatcatat tctaatgtgg gaatgccaat ttgataacgg tacatttcct
    16861 actctctttc ctccagtatt ttattactat tctactactt tcgtttgaaa agtctagtga
    16921 aaacatattt tattttagtt ctactccccc tatgctgaag ttcaaactaa gtcagtctct
    16981 cttctaattt gaaatcaatt ggtagggttg ttaaaaaaac ttccaattgt ttttcccagt
    17041 agtaccactc gtgagttcca gcgctatggc tataggtcac atcaaaacct agttttttga
    17101 gatttttcac tacgagatta ttggcttcgt acaagaaatc ctgttcgcca caccacgccc
    17161 aaagtttggt ctttttatcc gattttttag ccagactttc aagagaatag ggactagttg
    17221 tccagtcttt aatctctcca aaaacacctc tccagtaggc tggacttccc agattttgac
    17281 tctcaggaga aaaatcttga aagctcaatg cacctgaaaa gctagctgca tgagaaaaac
    17341 gatttgtcgc aagagccagt ttgaagcagc cgtagcctcc catagaaaga ccagcgataa
    17401 aggtcttttc acacttgcta gtcatattag ggaagaagcg tttcagaacc tgtggcaatt
    17461 cctctgctaa agccgtgtag tagtcaaaac catactgggt atcggtgtac caaccattgc
    17521 tggtattggg cataacaacg atgagattag ttcctcgaag caagcgttct acattggtcc
    17581 gcttaagcca actattatga tttccagaca tcccgtgtaa aaggtacaag acgggaatat
    17641 cttcacactc tggttcttcc actcgattgg catcagggta gaggacattc accccccact
    17701 ccatatccaa tacttgtgag taatactcga ttttcattac tgccatgatt ttctccttct
    17761 atttttctat aagaaaaagc cgaaactcga ctttctctct gtttatttca acgattattt
    17821 tgcttccatg actactggta aaatagctgg acgacgcttg gtttggtcaa agagatactt
    17881 ggtcaaatta tctcgaacct tccctttaag atctgcccag tcaaagtcat ctccttgaag
    17941 atactcttct accgtttggt taatcaattc tgaactttca cggagaatat cgcgactctt
    18001 cttgagataa acaaatccac gcgtgtgaac acgagcccta gccacaattt tcttctcacg
    18061 acggttgact gtaatagcca cgatgaaaat tccatcctct gacaagacct tacggtcacg
    18121 aagaacaaca tttccaacat caccaatggc attcccatca atcaagatat ctcctgctga
    18181 aaccgatcca gctggaacaa agtctccatt ctcgtaagcc atggtcgtcc cctttttagg
    18241 aatgaagatg cgttctggca acatcccaac tgccatggca gccttagcgt gagcatccaa
    18301 ctcacgatac tccccttgga cagggaagag gtacttaggt tgcaaaagat tgatcatcag
    18361 ctgcaaatca cgcacatttc cgtgccctga tacatgtaaa ctttgggtaa tcaatttgac
    18421 aaccccacct gcctgataaa tcatattttc cacacgcgca acaaaggctt ctttagcaat
    18481 agacggagcc gtagcaatat agactaggtc cccatccttg atttctacat aacgatggcg
    18541 accaatcgac atcttacgaa gtccattgat aggctcaccc atacgacctg tctcaagaat
    18601 aatcaactca tggtcttcaa agcgagacat atctttaggc ttaatcaaaa gaatttcgtt
    18661 ggctaaagac aacttcttaa gacgaatcgc tgtgcggacg atattttcaa tatcaaatcc
    18721 tgtcaagacg atacgtcgac ctgttttatc cgcagcgtca aaaatctgct gaatacgaga
    18781 aagattactg gaaacagctg caacgatgat acgaccttcc cagtcagcaa tagtttgggt
    18841 aatttcatcc ctaacttcac tttcactagc cacctgaata ttgctgtctg cattggccga
    18901 atcactgagg agagccagga cgccgtcacg accaatctct gccaaacgag caaaatcagt
    18961 tgcataagat tcactagccg tttggtcaaa tttgaagtca cctgtataaa cgatgcttcc
    19021 ttccgatgtc ttcaagacaa ttcccagact ctctggaacg gagtaagtcg tagggaagaa
    19081 ggaaaccact gtcccaccaa aatcaatctc cgtattctca tcaatgacat ggaaatcatt
    19141 aaatttctta acggcatcat ttcctttgac aaagagcttt gccaactcaa tggtcaactc
    19201 agacccaaat acaggaactt tagcctctgc caagagatac ggtagagcac caatggcatc
    19261 cgcatgcccg tgggtcaaga aaaccccagc aatacggtcg ctattttcaa aaaggtaatc
    19321 catgtttgga atcaccacat cgacccctaa ttgttcattt tcaggatatt ttaaccctac
    19381 attcaaaaca aaaatggact ctccaatttc agcaatgtac atattttttc cattctcacg
    19441 cacaccacca agtgttgtta aactgatatt actcattttt cctccaaaat cttagtttat
    19501 cttgattata gggcaattct accctcttat tctaaaagtt ctgatatttt cagccgaatc
    19561 ttttcctacc attataccat ttttttgatg attttcaaaa tgaaggtctg ttttcaaaaa
    19621 agagttgatt tcccaactct ttcctaactt ctactctttt tccatcaaaa aatcataaat
    19681 ttcttgcacc gtacccagcg ccatcatttc ttggtcttta acggtttgtt tgagattttg
    19741 gtaaatttga ctttctccta tctcccgctt tggcgcctct ttattgactg tcatcacacc
    19801 atcttttatc gtcacaaagc ctagttcttc aaatacttga atcatcttga ccagcaagat
    19861 ttgttgaata ttaagatatg cagccaaatc tttcagcttg tagcgaatat caaactctgg
    19921 gaactggtaa atagtcttgt acaatttggc aaactgatct ctagtcccat aacctgtcag
    19981 ataataagcc ttgtcaatat catttttgaa atagacagca gagaaatgct gttcctgaaa
    20041 aatggtcttc agctgagtaa tatcctctgg aatgtttttt acgacaacag cttcactagc
    20101 cgcaagattt ggcagttctc caggtaaatc caagactgga acaccttctg gcaagactgc
    20161 attttttcca cgaatgttaa aaagttgaac accttccact cgcgcatcca ccatcatcaa
    20221 ctggagggca gtttggccat tccattggtt gacagacaat ttaaccgcta actctagatt
    20281 cttggtttga gaaaactctg tcgcccatct gccttgacca aaggctacca cttcaaaact
    20341 cgcctcaccc ttggaaattt tcagctttag atgggcatta cctgccccca tagtacgagc
    20401 actttcgacc tgaaaattct tgatataaaa aataggtttc tgattatcca ttccaaaagg
    20461 agctaaacgt tcaaaacttt tgaccgtttc caagctaagt gcctccaaat ccaactcttc
    20521 atctaggttt aacttattct tgccaccagc atctgcacct ttttcacgaa cataatcttc
    20581 caaaacctga gataaatctg agagttgctc aacttccagc gtcatacccg ctgcacctgc
    20641 atgacctcca aaggtgatga agaggtctcg atggggatcc agagcttcaa aaatatcgac
    20701 cgcttccaca ctacgagcac tgcccttggc acgaccgtct tctatattaa gaacaatgac
    20761 tgtctgtccc aattcttcca ataaacgacc agccacgatt cctagaaccc caggattcca
    20821 gccttccttg gccaagacct gaaccttctt ctcaggatcc accatggtct tggcttcttc
    20881 atagatagac tgaacgattt ccttgcgctc ttcgtttttc tggtgaatca taagggcaat
    20941 ctcatgcgct tcctcatcat caaatccagt caacaaatca atggcaggat tgggatcatc
    21001 caagcgaccc aaggcattca aacgaggagc aatctggaaa ccaaccgttt cttctgttac
    21061 ttcgttggca gcaatcccag ccatgtccag catttcttgc agaccaatgc gctgggtatg
    21121 acccaacatt tccagaccat attgaactaa gatacgattt tcatccgtca gactcaccat
    21181 atctgcaata gttccaatag cgaccaaatc aagcaattcc acttgcactt cttctaacag
    21241 ggcacaagcc aacttgaaag caactccaca accagccaaa tatttaaaag gataatccgc
    21301 atctggatgt tcaggatgga caatagcata agcatctggc agggtttcag gcatggaatg
    21361 atggtctgtc acaatgacat ctactcccat agactgagcc aatgcaatag cctcatgacc
    21421 agcaacccca ttgtccaccg tcacaatcaa ggaaatccct tcttgctcga taaagtattt
    21481 ataaacacta gcattagggc catagccatc ggtaaaacga tttggcaggt aaactcggca
    21541 ctcagcacca agttgttcca aactttcctt cacaatagaa gccgaagtca tgccatccgc
    21601 atcatagtct ccataaacaa gaatattttc cccttcttca atagcctgac gaatccgctc
    21661 cactgccttg tccatatcat ggagcagata agcatcatgt aagtcctcca aggaaggttc
    21721 taaaaacttc ttcagacttt cttggttctg aatccctctc tcaaacaata accgagccac
    21781 ctcaggaccc agtccagcct tcttggctat ctttgtaaaa tccgcatctt ctacctgcag
    21841 ggcaaactgc cattcataag taggtgttat caaaaagaca tccactcttt ctaagaattc
    21901 tattgcttca ttataacatg atttagacgt tttctctatc cagattgctt ttttataaca
    21961 ttttatagta tattgaaact agaatagtac acctctactt ctaaaatatt gttagaaatc
    22021 gatttgactg tcccgatcga tttttcctgt tcttatttca ctatagtgaa ttttttcaga
    22081 tatgatttga caagaacatt cttttattgt agaaccgtgt tataaaatat aacacaatag
    22141 agatctctca tggctttagt agaatttaaa aacgtcgaaa aatattacgg agactaccac
    22201 gcattccgca acatcaatct ccgttttgaa aaaggacaag ttgttgtcct gcttggacct
    22261 tctggctctg ggaagtccac tcttatccgt acgatcaatg gtttagagac tgttgacaaa
    22321 ggaagtctcc tagtcaatgg gcaccaagtt gctggtgcca gccagaaaga tttggtacct
    22381 cttcgcaagg aagtcggcat ggtttttcaa cattttaacc tttatccaca caaagctgtg
    22441 ttagaaaacg taacgcttgc acccattgaa gttctaggaa ttgataaaaa agaagctgaa
    22501 aaaaccgccc aaaaatatct ggaatttgta aatatgtggg acaagaaaga ttcctatccc
    22561 gccatgctat ctggtggaca aaaacagcgg atcgccatcg ctcgtggtct tgctatgcat
    22621 ccggaactcc tcctctttga tgaaccaaca tctgctcttg atcctgagac tatcggagat
    22681 gttctagcag ttatgcagaa actggcgcat gatgggatga acatgatcat cgttacccac
    22741 gaaatgggct ttgctcgaga ggttgcggac cgcattatct ttatggccga cggagaagtt
    22801 ttagtagata cgacagatgt cgataacttt tttgacaatc caagcgaacc tcgtgcccaa
    22861 caattcctca gcaaaattat caaccacgaa agtgacaaag tcaaataagg aggcgcctat
    22921 gaaaaaaaat tctttttatc agcattattg attagccttt tcggccttgc tgctgccaaa
    22981 ccagtccagg ctgatacaag tatcgcagac attcaaaaaa gaggcgaact ggttgtcggt
    23041 gtcaaacaag acgttcccaa ttttggttac aaagatccca agaccggtac ttattctggt
    23101 atcgaaaccg acttggccaa gatggtagct gatgaactca aggtcaagat tcgctatgtg
    23161 ccggttacag cacaaacccg cggccccctt ctagacaatg aacaggtcga tatggatatc
    23221 gcgaccttta ccatcacgga cgaacgcaaa aaactctaca actttaccag tccctactac
    23281 acagacgctt ctggattttt ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta
    23341 aacggcaaaa ccatcggagt cgcccaaggt tctatcaccc aacgcctgat tactgaactg
    23401 ggtaaaaaga aaggtctgaa gtttaaattc gtcgaacttg gttcctaccc agaattgatt
    23461 acttccctgc acgctcatcg tatcgatacc ttttccgttg accgctctat tctatctggc
    23521 tacactagta aacggacagc actactagat gatagtttca agccatctga ctacggtatt
    23581 gttaccaaga aatcaaatac agagctcaac gactatcttg ataacttggt tactaaatgg
    23641 agcaaggatg gtagtttgca gaaactttat gaccgttaca agctcaaacc atctagccat
    23701 actgcagatt aaggaggaca ccccatgaca gatttatcat cttggacagc ctattttcag
    23761 gattttggac aatttttcaa tggtttcctc ttcacccttg ccctagcggt tggttccttt
    23821 atcctcgcta tggttttggg catcttcttt ggtgccatgt caaccagtaa acgtccaatt
    23881 ttacgcattt tagctcgcat ctttgttgaa ttttaccaaa atactcccct cttggtgcag
    23941 tttgttattg ttttttatgg cctacctctt atcagtgacc atatcatcat gattccattt
    24001 tattggacag ccgttctctg cgtgggactc tatcacggcg cttatatcgc tgaggttatt
    24061 cgttcaggga ttcagtctat tcctagtggt cagatggagg ccgccttgtc gcaaggtttt
    24121 acctatatca gtgccatgcg cttgattatc ttgcctcagg ccttccgcat cattctccct
    24181 ccattgacca accaaattgt taacctcatc aagaacacct ctactgtagc tatcatctct
    24241 ggagtagact tgatgtttgt gactaagtct tggtcggctc tcaacggaaa ctatatccca
    24301 ggctttttag gtgctgctct tctctacttt gccctatgct tccctgttgc ccagtttggt
    24361 cgcaagatgg agcaagccaa caaaaaagcc tattcacttt aggaggttac tatggaatct
    24421 attttagaag ttttaacccc agataaccta gtctttatct ttaaaggatt tggcttgacc
    24481 ctctatattt ctctgattgc catcatcctc tctactatca tcggtacggt gctagctgtc
    24541 atgagaaatg gcaaaaatcc tgtcttgcga atcatctcca gtatttatat cgagtttgtg
    24601 cgcaacgttc ccaaccttct ctggattttt actatctttt tggtgttcaa aatgaaatcc
    24661 acaccagcag gtattacagc ctttactctc tttacatcag cagccttggt tgagattatt
    24721 cgaggcggtc tcaatgccgt agacaaggga caatacgaag taggaatgtc acaaggcttc
    24781 acctcagccc aaatcctcta ctacatcatt ctcccacaag ccatccgcaa aatgctacca
    24841 gccatcattt ctcagtttgt taccgtgatt aaggatacca gtctcctcta ctctgttatc
    24901 gccctacaag aactctttgg agccagccaa attctcatgg gccgttattt cgaaccagag
    24961 caggtcttca gtctttacat cctgattgcc ctcatctact tcagctttaa cctagcaatt
    25021 tctagcctgt ctcatatgct agccaaacgt tggcaacaag ctgcagaata atactcttcg
    25081 aaaatctctt caaaccacgt cagctttacc ttgccgtact caagtacagc ctgcagctag
    25141 cttcctaatt tgctctttga ttttcattga gtataaacag ccactctcca gttcaattgg
    25201 agagtttttt gatgatagta gatatttata gacctcaatt tgacaccata cattttctat
    25261 gataaaatgt aacaaattta tttacaacaa atcgaaatct aaatgaaatg gaattttcta
    25321 tgaaatcagt caaaggacta ctctttatca tagctagttt tatcttgact cttttgactt
    25381 ggatgaacac ttctccccaa ttcatgattc caggactagc tttaacaagc ctatctctga
    25441 cttttatcct agccactcgt ctcccactac tagaaagctg gtttcacggt ttggagaagg
    25501 tctacaccgt ccacaaattc acagcctttc tctcaatcat cctactaatc tttcataact
    25561 ttagtatggg cggtttgtgg ggctctcgct tagctgctca gtttggcaat cttgccatct
    25621 atatctttgc cagcatcatc cttgtcgcct atttaggcaa atacatccaa tacgaagctt
    25681 ggcgatggat tcaccgcctg gtttacctag cctatatttt aggactcttt cacatctaca
    25741 tgataatggg caatcgtctc cttacattta atcttctaag ttttcttgtt ggtagctatg
    25801 cccttttagg cttactagct ggtttttata tcatttttct atatcaaaag atttccttcc
    25861 cctatctagg gaaaattatc catctcaaac gcttaaatca cgatactaga gaaattcaaa
    25921 tccatcttag cagacctttc aactatcaat caggacaatt tgcctttcta aagattttcc
    25981 aagaaggctt tgaaagtgct ccgcatccct tttctatctc aggaggtcat ggtcaaactc
    26041 tttactttac tgttaaaaat tcaggcgacc ataccaataa tatctatgat aatcttcaag
    26101 ccggcagcaa agtaacccta gacagagctt acggacacat gatcatagaa gaaggacgag
    26161 aaaatcaggt ttggattgct ggaggtattg ggatcacccc cttcatctct tacatccgtg
    26221 aacatcctat tttagataaa caggttcact tctactatag cttccgtgga gatgaaaatg
    26281 cagtctacct agatttactc cgtaactatg ctcagaaaaa tcctaatttt gaactccatc
    26341 taatcgacag tacgaaagac ggctatctta attttgaaca aaaagaagtg cccgaacatg
    26401 caaccgtcta tatgtgtggt cctatttcta tgatgaaggc acttgccaaa cagattaaga
    26461 aacaaaatcc aaaaacagag cttatttacg aaggattcaa gttcaaataa gtaatcatac
    26521 tctcctggga tttcccagga gaatttttta tagccaaatg aaataagacc ggaacgatgg
    26581 aattttggca ttcaaatcaa ttgataagaa tattttatag tggagtgaaa taggatacga
    26641 acaaattgat taggaaaatc aaatgaattt atagaaatct tttagcagtt atgttgtcct
    26701 attctagttt caaaacgcta tagaagcagc attgtgctag tctagattca gtttactata
    26761 ctaaaacgag tagcttgaaa tcaaaaaacc caccctcaca ggcaggtttt atctgtatta
    26821 ttcagctaga ttatgcttta ccttctgaac cgaatacgtc gatacgttct tcaaccgatg
    26881 cttggatagc ttttacaccg tcagccaaga atttacgtgg gtcgaagagt tttttcttgt
    26941 cgtattctgc ttcgtttgct tcgtagtcac gagcaaattt acgagttgcg ttagcgaatg
    27001 cgatttggca ttctgtgtta acgttaactt tggcaacacc aagtttgata gctgcttgga
    27061 tttgctcatc aggaatacct gatccaccgt gcaatacgat tgggaatcct ggaagagctt
    27121 ctgtcaattt ttgcaagtgg tcaaggtcaa gaccttccca gtttactggg taagggccgt
    27181 ggatgttacc gataccagct gccaagaagt cgataccagt ttcaaccatt gctttagcgt
    27241 cttcgattgg agccaattca cctttaccga tgattccgtc ttcttcacca ccgatagtac
    27301 caacttcagc ttctactgag atacctttag cgtgtgcttt ttcaacaact tctttagcca
    27361 atttaaggtt ttcttcaact ggaaggtgtg aaccgtcaaa catgattgaa gtataaccaa
    27421 cttcgataca ctcaagtgca tcttcgtagt gaccgtggtc aaggtggata gctactggta
    27481 cagtgatacc cattgattca acaaggttag cgatcaagtt gcgagcaact ttgtaaccac
    27541 ccatgtattt agcagcaccc attgaagttt ggatcaaaac tggagctttt ttagcttctg
    27601 ctgcgcgcaa gatagcttga gtccactcaa ggttgtttgt gttaaatcca ccaactgcat
    27661 aaccgttgtc acgggctgct tggacaaatt tttctgctga aacgattgcc attttatcag
    27721 gcctcctgta tatttttatg ggtcatccca tttacattgt tcattttatc actttttgcc
    27781 aaaaaaatct agtttttccc gcagtttcga ttgattttct tctaactcca tctatgtaaa
    27841 ccctttctct ccctagtctt ggacgacttt tggaaaatct ataaagaagg ttaaactatt
    27901 ctcctccatc tcgaaacgat aagctaattt ttcatgttct aatagactct taaccacaaa
    27961 gagccccata ccagacccct tgaccttgcg actggcattg tcagaaaaag actgggctag
    28021 tttttcttgt tcctctgagc tacagctatt ttcgataaaa agttctcctt ctctttctcc
    28081 aattcgaact aagccacctg gaacagagtg cttaatggca ttgctgatga gattagaaag
    28141 aatcaacttc ataactgatg ggtttagata agcctgctga tgggtcaaac tattgtctat
    28201 ctggagctct ctttccttgg ctagcaaggc ataatctttg accagatttt gcgtcatctg
    28261 gaggaggtca attgtttccc tatcatctcg caattcctgc acagaagaga gggaaagtat
    28321 ctgcagaaca tggtgattga gttcatccac aatccccaag gcaactccca gatactggtc
    28381 tctatcctta taacgaccga tattctctct catattttcg attaggattt tcaaactagc
    28441 cagcggtgtt ttcaattcat gagaagctcc tcgtaggaat tcgaccttca tcttctccag
    28501 ctggagaatg gcttcattct tttcatgcaa gtccgcaata acagtcaaga gatgctggta
    28561 gaggctattg atttgttcct tgagattacc tatctcatcc ttagaatcca cgcgcaatcg
    28621 cacttgggaa tccaggtcca tcatccgacg ggtcacccgc ttgatttcca aaatcggtgc
    28681 aacaatagtc cgagcgtaga tgtaggccac caaaagggaa atcagaaagg aggccagcaa
    28741 ggtataggga agaaactgga gactgatttg ctccgcttcc ttttgtaaat ccatggaagc
    28801 tagaaactgg agaatcatag taccaccgtc ttgcgttttc acctcgcgct cctcaataaa
    28861 gagagaggtt gtctggcggt ctgtgtccag aggaagactg tccttgactt ctaacttgtc
    28921 ctcggtcatc tcacctttga cggtcccctt gatatcacta gtctgggaat acaagtctaa
    28981 cacttgctcg atactctgcc tatctttccc ttctagggac tgggcaatgg ctgttgcctt
    29041 ttgaccaatg gtttcctgac gatgactcag ataagtcgaa ggaaaaagaa aataaatagc
    29101 taaatgaagg cagataacca gaacactaaa tatcgagaag gtatagataa atatctttgc
    29161 aaataaacct gttcgtttca ttttcgctcc aatttataac caacattgcg cacagtgagg
    29221 atacaatcca agtctagctt tttccgcaat tccttgatat aaacatcaat aacacggtca
    29281 aagggaacct catctgtcgc tttccagacg gcatcgataa tctgagaccg agtcaaggcc
    29341 cggccttcat ttttcactag atagtccaga atttccaact ctttggcatt gataggcact
    29401 tcttgacctg cgaggcttgc actgtagctt tcaaagtcca ccttggtagc cttgtaagaa
    29461 aagattcgtc ctgtatcgta gtagcgcttg aaaatcgcgt ccaccctcac ttttaagagg
    29521 gagagggaga aaggtttttc cagatagcca tctgccaaag aggcaaaggc actcatcttg
    29581 tattcctcat cctgaaaagc tgtcaacatc aagacaggaa cctgactggt tttacgaatc
    29641 tcagctagaa cttctaagcc gttaagcttg ggcatctgga tatccagtaa aaccagggcc
    29701 acctcatagc tagaaaattg ctccagagct tcctgaccgt ccgctgcctc aatagtttca
    29761 tagccacaat ccgtcaaata atcactgacc ccctcacgga tcatctcttc atcttctaca
    29821 attaaaattt tcatacttta actgctctct attttttatt tttcttagaa taaataccta
    29881 ctctattttc tattatagtc tcttgctggc cttttgtctg taagtaactg atcactagat
    29941 aaaacgttgt gaaattcctt tctcataaat tccatagctt tagtatatta tatttaagca
    30001 ataaagtaca aagaaaacaa ctgaaagcaa tgattttcac cactgctttc ggatttattt
    30061 tgaattgtta aatagccatt cctatccact attcttgaat agaaacacaa gatgcaatct
    30121 ttattccaga ctcatttttt caaatttatt caccatccag caagagctct tttggttgtt
    30181 ttctaaggag attgcttgaa gcaagcgcca taacgagaac cactagaacc aaggcaagga
    30241 caaaaatgat gataaagtct gatgtctgaa tagaaatgtc taggctcgac aaggtcttgc
    30301 taaagccatc tacttctgca ccaccaccaa ggttagaggc ttgagccgcc ttactagcct
    30361 gtttggcaac acctgaagtc acattggcaa ggacagtgtt tccaattgca cgggcagtgt
    30421 aattagctag gaagtaagca gaaactagag cagggatagc aatcaagata gattcggtga
    30481 tgaattgacc caagatactt gcctgcttga ggccgataga gaggagaatt cccacttcct
    30541 tgcgacgggc gttgatccaa aggctgagca agagggcaag gaggagaact gagaagctca
    30601 agctacccca gaagaggagg ttggccatct tgtacatacc agagatagat tgctcaagag
    30661 ctgggtagtt agaggagctc ttgacgagtg tgtagctctt ccagttgata ccactgatgc
    30721 cattcaactc tttcataaca tcatccaagt tcttgtctgc tgttacaaag aaggttgcgt
    30781 ccccataaat ggctgtgtct tctgtgtatc cataaagttt tgcagcagtg tgaatgtctg
    30841 taatagctgt gttttcgtaa agttcttgtg agtaggttac tgctgactta ttatgaccat
    30901 caaagagtcc cttgattgtc acttcaactg tttccttggc tcctttttca ttatctgcat
    30961 cgtagatatt agagtccagt ttaaccttgt cccctacttt ccagccgtgt ttggctgcca
    31021 agtccttgtg caagaggatt ttatccttgt cgtcgttggt taagtgctct ccttcgacta
    31081 gtttataaga accagagaca aacttgtctt ctttagagga gtcattgaca cctgtaatca
    31141 tcaagctact tccaaaacgt ttggcacgat cagcagtgag attcttcttg gtttctggcg
    31201 tttcaatcag gtcatatcca gtcaaatctc cgatagcgtt gatacgtttg acataagact
    31261 caatggcctt gttttcggtg atttttttga tgtcttcacc cttgatattc ccagcaccgc
    31321 gaggcgttcc ttggttgacg cgacgattga tttgcatgga gaagctattg gtgatatttt
    31381 taaaggtctc ctgagaagcc ttggcagtag ctcccttgat tgacaagccg accaaactca
    31441 agctcgccat gaggagaata atcaggaaga tgacaatcga tttgaaaaac ttccttgtaa
    31501 cataggcaaa tgcgttgtgt aacatagatt ccctttctag attttgtttt aatcattcta
    31561 tcaaaataag ctcaaattat ttactagtat tgcgcgtttc agtcagtttc ttatccttta
    31621 attcaagtgt aatatctgac gcttgtgcca cttctttact gtgagttacg acaatcacac
    31681 atttacctgt tttctgggca agtgatttga gtagttcgac aatatctcca gcagttttag
    31741 gatccagatt tcctgttggc tcatcagcta gaataactgg agcttctgag accaaactgc
    31801 gagcaatggc aacacgttgc tgttgaccac ctgataactg gagaacattc cgcttgatct
    31861 ggctttcatc caaaccaagc tcaagaagtg tattcttgct tgcctttttg ttgaccaatc
    31921 ggatattttc cagcggagaa agataatcta tcaagttata attttgaaag accagggaaa
    31981 tatggtgcat gcgatggtaa gaatagccct tcttacgaat atcctctcct tgaaaaagga
    32041 tagaaccttc aacaggacta tctagaccag caagtaggga caagagtgtg gattttcctg
    32101 ctcctgactc cccaataata ctgtaaaatt ttccgggttc aaaattataa tcgatctgat
    32161 ataggactgc ttcagcagta ttcttataac ggtaggtaac atcttgtaat tgtaataaag
    32221 tcatgatttc tccttcttaa ctaatagatg ataaaatttc tttcggtgat tttctaaata
    32281 agaataggaa acaaagggtt acagataagc aactaagcag aactagaaaa acataggatt
    32341 ctgcaaaaga taagatacta gttgataaac tgcttgcttt ggctagtgta tcttgtaagc
    32401 ttgcctgatc tccacttgct agtagagttt ggagtaggta agttgtgatt ccgtttcctg
    32461 caacaaatgc tggaagcaaa gctccaagag ataccaaaac tacctctaaa cagaattgta
    32521 ggaagatcga gcccttgcct tttccaagtg caagtaaaat ccccacttca tagacccgtt
    32581 ctctcaacca gagagacaaa accagaatta aggctccagc tcctgctatc aacatcccat
    32641 aaaggaagat ggtcaggaag gtttggaaag ttgcaactga gtctttgatt tgttcaaaag
    32701 ccttgttttc cttttcgact tggtagcctt gattttccaa ggccaagttt tctacctgct
    32761 tcatgagtcc gtccatttcc ttaggatttt ctacatagaa gcgtgctgca ctgacttgag
    32821 cttcactatt gcccaaaagg gtttggctac tttcatagtc tgtaaagact tgattttcac
    32881 tgaagtcaga agacaagcct gtgaatttct cttgtttttt accagaaaag atgccaataa
    32941 tctcaaactc tactgtttgt ccttttccag attcagactg accagcatcc aagccaatct
    33001 tgtcatgaag tgaaagaccg ttcttcttag ccaattcttc gtggataagg attttcttgg
    33061 aatccccttt ttgaaggtgt cgcccttctt ttagattgaa agccgaactg gtaaaggtta
    33121 catccttgga tgaatcctca agagccgtta agctaaccaa gttattgtct gcagctgata
    33181 aatcatcacg ctccacgctc tgctcgccag tcactgcttc cttgtctttt agttttgcga
    33241 ccgtctcaag ttcaggagag acattttcca gccccttaat cttgcttaca gatgctaggt
    33301 ctgacaactt gaatgtctga ccattctcta tcttcttaat agaaaaagat gtattgagtg
    33361 atttataaag attgctttct actgttttgt tggacttcat cagagtcaaa caggctgaaa
    33421 ttccggccaa taagaccaat aaaatcagaa ataaaataaa acttctcagt cgctttctgc
    33481 tgacataagc ccaagatctt tggattggat tcatttgtca cctccatatt tgtaagacta
    33541 ttataaaacc caaatatgaa atgtttatga aatacgaaaa aaaaa
//
LOCUS       DAVKXA010000020        33392 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKXA010000020 DAVKXA010000000
VERSION     DAVKXA010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.020"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            69..566
                     /locus_tag="VW883_001013"
     CDS             69..566
                     /locus_tag="VW883_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0274170.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            566..2221
                     /gene="dnaX"
                     /locus_tag="VW883_001014"
     CDS             566..2221
                     /gene="dnaX"
                     /locus_tag="VW883_001014"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0274171.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2249..2443
                     /locus_tag="VW883_001015"
     CDS             2249..2443
                     /locus_tag="VW883_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0274172.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2593..3363
                     /gene="sufC"
                     /locus_tag="VW883_001016"
     CDS             2593..3363
                     /gene="sufC"
                     /locus_tag="VW883_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0274173.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3391..4653
                     /gene="sufD"
                     /locus_tag="VW883_001017"
     CDS             3391..4653
                     /gene="sufD"
                     /locus_tag="VW883_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0274174.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4664..5890
                     /locus_tag="VW883_001018"
     CDS             4664..5890
                     /locus_tag="VW883_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0274175.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSSVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5877..6317
                     /locus_tag="VW883_001019"
     CDS             5877..6317
                     /locus_tag="VW883_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0274176.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDII
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6371..7783
                     /gene="sufB"
                     /locus_tag="VW883_001020"
     CDS             6371..7783
                     /gene="sufB"
                     /locus_tag="VW883_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0274177.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8014..9255)
                     /locus_tag="VW883_001021"
     CDS             complement(8014..9255)
                     /locus_tag="VW883_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0274178.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9358..10467
                     /locus_tag="VW883_001022"
     CDS             9358..10467
                     /locus_tag="VW883_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0274179.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRIQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11113..11460
                     /gene="ssrA"
                     /locus_tag="VW883_001023"
     tmRNA           11113..11460
                     /gene="ssrA"
                     /locus_tag="VW883_001023"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11630..11717)
                     /locus_tag="VW883_001024"
     tRNA            complement(11630..11717)
                     /locus_tag="VW883_001024"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11681..11683),aa:Ser,seq:gga)
     gene            11879..12619
                     /locus_tag="VW883_001025"
     CDS             11879..12619
                     /locus_tag="VW883_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0274180.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12616..13527
                     /gene="pfkB"
                     /locus_tag="VW883_001026"
     CDS             12616..13527
                     /gene="pfkB"
                     /locus_tag="VW883_001026"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0274181.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13524..15476
                     /locus_tag="VW883_001027"
     CDS             13524..15476
                     /locus_tag="VW883_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0274182.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAILFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15640..17865
                     /locus_tag="VW883_001028"
     CDS             15640..17865
                     /locus_tag="VW883_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0274183.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17910..18338)
                     /locus_tag="VW883_001029"
     CDS             complement(17910..18338)
                     /locus_tag="VW883_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274184.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18476..19618
                     /locus_tag="VW883_001030"
     CDS             18476..19618
                     /locus_tag="VW883_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0274185.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19627..20841
                     /gene="thiI"
                     /locus_tag="VW883_001031"
     CDS             19627..20841
                     /gene="thiI"
                     /locus_tag="VW883_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0274186.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20976..21789
                     /locus_tag="VW883_001032"
                     /pseudo
     CDS             20976..21789
                     /locus_tag="VW883_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            21811..22146
                     /locus_tag="VW883_001033"
     CDS             21811..22146
                     /locus_tag="VW883_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV0274187.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGRVQFFTLSSVDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVGLMA"
     gene            22143..22550
                     /locus_tag="VW883_001034"
                     /pseudo
     CDS             22143..22550
                     /locus_tag="VW883_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22563..23729
                     /locus_tag="VW883_001035"
     CDS             22563..23729
                     /locus_tag="VW883_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0274188.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFEPQYCLATSRRANAHYVY
                     SEENLLAKYSQQFKVKKIMPEAFAELQGDYFYMLTTPSRQEMDQMIADFGQRQE"
     gene            24063..25556
                     /locus_tag="VW883_001036"
     CDS             24063..25556
                     /locus_tag="VW883_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0274189.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESNAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPIRDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25569..26462
                     /locus_tag="VW883_001037"
     CDS             25569..26462
                     /locus_tag="VW883_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0274190.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNHNLLVR"
     gene            26536..29887
                     /locus_tag="VW883_001038"
                     /pseudo
     CDS             26536..29887
                     /locus_tag="VW883_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            30131..30232
                     /locus_tag="VW883_001039"
                     /pseudo
     CDS             30131..30232
                     /locus_tag="VW883_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(30473..30943)
                     /locus_tag="VW883_001040"
     CDS             complement(30473..30943)
                     /locus_tag="VW883_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0274191.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(30960..33233)
                     /locus_tag="VW883_001041"
     CDS             complement(30960..33233)
                     /locus_tag="VW883_001041"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0274192.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELKVKLPRKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCHAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT        10057 a         6017 c         7312 g        10006 t
ORIGIN      
        1 aaaatccttt gtttactaaa caagggattt ttcttttgtc tctgctcctt ttttgatata
       61 atagttctat gttaaaatca gaaaaacaat cacgttatca aatgttaaat gaagaattgt
      121 ccttcctatt ggaaggcgaa accaatgttt tggctaatct ttccaacgcc agtgctctca
      181 taaaatcacg ttttcctaat accgtatttg caggctttta tttgttcgat ggaaaggaat
      241 tggttttagg tcccttccaa ggaggtgttt cctgcatccg tattgcacta ggcaagggtg
      301 tttgtggtga ggcagctcac tttcaggaaa ctgttattgt tggagatgtg acgacctatc
      361 tcaactatat ttcttgtgat agtctagcta aaagtgaaat tgtggtgccg atgatgaaga
      421 atggtcagtt acttggagtt ctggatctgg attcttcaga gattgaggat tacgatgcta
      481 tggatcgaga ttatttggaa caatttgtcg ctattttgct tgaaaagaca acatgggact
      541 ttacgatgtt tgaggaaaaa tcttaatgta tcaagcactt tatcgaaaat atagaagtca
      601 aaacttctcc cagttagttg gtcaagaagt tgtggctaag actcttaaac aagcggtgga
      661 gcaagagaaa ataagtcacg cttatctttt ttctggtcct cgtggaacgg gaaaaaccag
      721 tgttgctaaa atctttgcca aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg
      781 caataactgc tatatttgtc aagcagtgac ggacggtagt ttagaagatg tcattgaaat
      841 ggatgcagct tctaataatg gggtagatga aattcgcgaa attcgtgata aatctaccta
      901 tgcgcctagc cttgctcgtt ataaggttta tatcatagat gaggttcaca tgctgtctac
      961 aggggctttt aatgccctcc taaagacgct ggaagaacca acacagaatg tagtctttat
     1021 tttggccact actgaattgc acaagattcc tgctactatt ctatcccgtg tgcaacgttt
     1081 tgagtttaaa tcaattaaga cacaggatat taaggaacat attcactata tcttagaaaa
     1141 agaaaatatc agttctgaac cagaggctgt ggaaatcatt gccagacggg cggaaggtgg
     1201 aatgcgggac gccttgtcta ttttggatca agccctgagt ttgacacagg gaaatgagct
     1261 gacgactgct atctctgaag aaattactgg caccattagc ctatcagcct tggatgatta
     1321 tgtggcggcc ttgtctcaac aggatgttcc caaagctttg tcttgcttga atcttctttt
     1381 tgacaatggt aagagcatga ctcgttttgt gaccgatctt ttgcactatt taagagactt
     1441 gttaattgtt caaacagggg gagaaaatac tcatcatagt tcagtctttg tagaaaattt
     1501 ggcacttcct caaaaaaatc tgtttgaaat gattcgctta gcaacagtga atttagcaga
     1561 tattaagtct agtttgcagc ccaagattta tgctgaaatg atgaccgtcc gtttggcgga
     1621 aatcaagccc gaaccagctc tatcaggagc ggttgaaaat gaaattgcta cgctgagaca
     1681 ggaagttgcc cgtctcaaac aagagctttc taatgcaggt gcggttccta aacaagttgc
     1741 accagctcct agtcgaccag ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt
     1801 gcaatctatc ttacaagagg ccgtcgaaaa tcctgattta gcacgtcaaa atctaattcg
     1861 tttgcagaat gcctggggag aggtaattga aagtctaggt gggccggaca aggctctgct
     1921 agttggttct caaccggttg ctgccaatga acaccatgct attcttgctt ttgagtctaa
     1981 cttcaatgct ggtcaaacta tgaaacgaga caatctcaat accatgtttg gtaatatcct
     2041 cagtcaggcg gcaggttttt cacctgagat tttagctatt tccatggagg aatggaaaga
     2101 agttcgcgca gccttttcag ccaaagccaa atcttctcaa actgaaaaag aagtagaaga
     2161 aagcctgatt ccagaaggat ttgaattttt ggctgataaa gtgaaggtag aggaagacta
     2221 aagaaagatt tcatgataca ataagtttat gaataaacaa caatttatta ttatggcgct
     2281 atttacagct gctgagacct attttttcaa tgaagcctgg atgactggcc gctatattat
     2341 ggcagccttt tgggcaattt tactctttag aaatttccga gtcagttatg tgatgggtaa
     2401 aatcgttgat gtcatcgatc agcattttaa taggaaagac tagccctcag cttccagaca
     2461 aaatcaaagc cttttaggct tttttttgtt atactagaaa agtatattta tagaattttt
     2521 gctctatttc tggggaaatc agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag
     2581 aaaggaacta tcatgtcagt aatagagatc aaagatcttc acgttgagat tgaaggaaaa
     2641 gaaattttaa aaggggttaa cctgaccctg aaaacaggag aaattgccgc tatcatggga
     2701 ccaaatggta caggtaaatc gactctttct gccgctatca tgggaaatcc aaactatgaa
     2761 gtaactaaag gtgaagtttt gtttgatggc gtaaacatcc ttgagttgga agtggatgag
     2821 cgtgcgcgta tgggactttt ccttgctatg caatacccat cagaaatccc tggaattacc
     2881 aatgctgagt ttcttcgtgc cgctatgaat gcgggtaaag aagatgatga gaagatttca
     2941 gttcgtgagt ttattactaa gctagatgaa aaaatggaat tgctcaacat gaaagaagaa
     3001 atggcagagc gttacctcaa cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt
     3061 cttcaacttt tgatgttgga gccaacattt gctcttttgg acgagattga ctcaggtctt
     3121 gatattgacg ctcttaaagt tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt
     3181 ggtgctatga tcatcactca ctaccaacgt cttttgaact atatcacacc tgatgtggta
     3241 cacgtgatga tggaaggtcg tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg
     3301 gaacgtgaag gatacgcaaa actagctgaa gaacttggct acgactacaa ggaagaattg
     3361 taattccctc gtatctttta ggagaagtaa atgactagag aaaatattaa acttttttca
     3421 gaaatgcacg ctgaaccaag ctggttggct gatctccgtc aaaaagcttt tgacaagatt
     3481 gagactttgg aattaccagt tattgagcgt gtcaaattcc accgttggaa tctgggtgat
     3541 ggaacgatta cagaaaatga gccatcagca aatgttccag atttcacagc tttagatcat
     3601 cacttgaagt tggtgcaagt aggaactcaa actgttttcg aacaaactcc agttgagtta
     3661 gctgaacagg gtgttgtctt cacagacttt cactcagctt tagaagaaat tccagagctg
     3721 atcgaagaat tcttcatgtc atctgttaag tatgatgatg acaagttggc ggcttaccac
     3781 acagcttact ttaacagtgg tgctgtactc tatattccag ataacgtaga aatcacagag
     3841 ccaattgaag gaattttcta ccaagatagc gatagcaatg tgccgtttaa caagcatatt
     3901 atgattatcg ctggtaaaaa ttctaagatt agttatctgg agcgtttaga gtcacgcggt
     3961 gaaggaagtg acaaagtaac tgccaatatc acagtggaag tgattgcacg ttctggtgcg
     4021 caagtcaagt ttgctgctat cgaccgtcta ggtgaaaacg tcactgccta cattagccgt
     4081 cgtggtaaat taggcaacga tgcaagtatt gactgggcta tcggtgtcat gaacgaagga
     4141 aatgtcgttg ctgattttga tagtgacttg attggtaatg gtagccatgc tgacctcaag
     4201 gttgtagctc tttcaagtgg tcgtcaggta caagggattg atactcgtgt aactaactat
     4261 ggctgcaact ctatcggaaa tatcctacaa catggggtta tccttgaaaa agcaactttg
     4321 actttcaatg gtatcggcca catcatcaag ggtgctaagg gagcagatgc gcaacaagag
     4381 agccgtgttc tcatgctttc agaccaagcg cgttcagatg ctaacccaat tcttttgatt
     4441 gatgaaaatg atgtcactgc aggacacgca gcgtctatcg gacaagttga tccagaagac
     4501 atgtattacc tcatgagtcg tggattggat aaggcaactg cagagcgttt ggttgttcgt
     4561 ggtttccttg gatctgttat cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt
     4621 gcaactatcg aagagaaatt gtcaaaacgc taaggggaag cctatgttag atgtagaagc
     4681 gattcgcaag gattttccaa ttttagatca gattgtcaat gatgaacctc tggtctatct
     4741 ggacaatgct gcgacgacac aaaaaccact agtagttctg aaagctatta acagttacta
     4801 tgagcaggac aatgccaatg ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc
     4861 ttcttatgaa gctgctcgtg aaaccattcg taagtttatt aatgcaggct ctacaaagga
     4921 agttctcttt accagaggaa cgacaaccag ccttaactgg gtggcacgct ttgctgagga
     4981 aattctcgct gagggagacc aggtcttgat ttcagtaatg gaacaccatt ctaatatcat
     5041 tccatggcag gaagcttgtc gaaagactgg agcagagctt gtctatgtct atcttaaaga
     5101 cggtgccttg gatatggagg atttgcgagc taaattgact gataaggtta aatttgtttc
     5161 cctagctcat gcctccaatg ttcttggtgt ggtcaatccg atcaaggaaa tcactcaatt
     5221 agcccaccaa gttggggcaa ttatggtagt ggatggtgct caatctacac ctcatatgaa
     5281 gattgatgtc caggacttgg atctggactt tttcgccttt tcgggtcaca agatggctgg
     5341 tccgactggt atcggtgtcc tttacggcaa agaaaagtat cttgagcaaa tgtctccagt
     5401 agaatttggc ggcgagatga ttgattttgt ctacgagcaa tctgctagtt ggaaggaatt
     5461 gccttggaaa tttgaggctg gaacgccaaa tatggcagga gctattggac ttgcgactgc
     5521 agttgattat ctggaaaaga ttggtatgga tgccgttgaa gctcatgaac aggaattaat
     5581 tgcgtacgtc tatccaaaac tgcaggcaat tgagggattg accatttacg gttctcagga
     5641 tttggctcaa cgttcgagtg ttattgcctt taacctaggt gatctccatc ctcacgatct
     5701 tgcgacggct ctggattatg aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc
     5761 cttgcttcag tatttggaag tcccagcaac agctcgtgca agtttttata tctacaatac
     5821 caaggcagat tgcgacaaac tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg
     5881 cactttctaa actagatagc ctttatatgg cagtggtagc agaccattcg aaaaatccac
     5941 atcaccaagg gaagttagaa gacgctgagc aaatcagtct caacaatccg acttgtgggg
     6001 atatcatcaa cctctctgtc aagtttgatg cagaggaccg tttggaagat attgcttttc
     6061 taaattcagg atgcacgatt tcaactgctt ctgctagtat gatgacagat gccgttttag
     6121 gaaaaaccaa acaagaaatt ttagaactgg cgactatttt ttctgaaatg gttcaagggc
     6181 aaaaagatga gcgtcaagac caacttggag acgcggcatt cttgtcaggt gttgccaaat
     6241 tccctcaaag aatcaagtgt gcaaccctag cttggaatgc ccttaagaaa acaattgaaa
     6301 atcaagaaaa acagtaagac aagtttcttt tgtcttatga attattagaa atgaagaaag
     6361 aaaggatatt atggctgaag aaagagtaga accaaaacca attgaccttg gtgaatataa
     6421 atttggtttc catgacgatg tagagcctgt cttatcgaca ggaaaaggac tcaacgaagg
     6481 tgttattcgt gaattatctg ctgctaaggg tgagcctgag tggatgttgg agttccgttt
     6541 gaagtcttat gaaaccttca aaaaaatgcc catgcaaact tggggagcag acttgtcaga
     6601 gattgacttt gatgacttaa tctactatca aaaaccatct gacaaaccag cccgttcttg
     6661 ggatgatgta cctgaaaaga ttaaagaaac ctttgaacgt atcgggattc cagaagctga
     6721 acgtgcttat ttagcagggg cttctgccca gtacgagtca gaagtggttt accacaacat
     6781 gaaggaagag ttccaaaaat taggtattat ctttacagat acagattccg cactcaagga
     6841 atacccagac ttatttaaac aatactttgc gaagttggta ccgccgacag ataacaagtt
     6901 ggcagccctc aactcagcag tatggtcggg tggaactttt atctacgttc caaaaggtgt
     6961 caaggtagat attccacttc aaacttattt ccgtatcaat aacgaaaata taggtcagtt
     7021 cgaacgtacc ttgattatcg ttgatgaggg agcaagcgtc cactacgtag aaggatgtac
     7081 agcaccaaca tattcaagca atagcttaca cgctgccatt gtagaaattt ttgctttgga
     7141 cggagcttat atgcgttata caactatcca aaactggtct gataacgtct ataacttggt
     7201 aacaaagcgt gctaaggctc aaaaggatgc cactgttgag tggattgatg gaaacttggg
     7261 tgccaaaacg actatgaaat atccatctgt ttaccttgat ggagaaggag cgcgtggtac
     7321 catgctctct atcgcctttg ctaatgcagg gcaacaccaa gacacgggtg ctaagatgat
     7381 tcacaatgct ccacatacca gctcgtctat tgtgtctaaa tctatcgcta aaggtggagg
     7441 aaaggttgac taccgtggac aagtcacctt taacaagaac tctaagaaat ctgtttccca
     7501 cattgaatgt gataccatta tcatggatga cttgtcagca tcagatacta ttccatttaa
     7561 tgaaattcac aactcgcaag tggctttgga acacgaagcc aaagtatcta agatttcaga
     7621 agagcaattg tattatctca tgagccgtgg attgtcagaa tctgaggcaa ctgaaatgat
     7681 tgtcatggga tttgtagaac cctttacaaa agaacttcca atggaatacg cagttgagct
     7741 gaaccgcttg attagctatg aaatggaggg atcagttgga taaaatttga ttttatactc
     7801 ttcgaaaatc tcttcaaacc acgtcagcat cgccttaccg tatgtatggt tactgacttc
     7861 gtcagtttca tctacaacct caaaacagtg ttttgagcaa cctgaggcta gcttcctagt
     7921 ttgttctttg attttgagta ttagatttac tcaaaatcaa ggattttgaa gatgaacttg
     7981 tatcaaaaaa tcgcggttta aaatcgcgat tttttataat ttctcgttaa caaagcggac
     8041 aaactgattc caccaaactt ttaagaagaa ggctttttca attttcttgt ctgctaccat
     8101 ttcgaaacta gggcgctctg tggtgatgta accttgacca atcaagtcct tgtcttcata
     8161 agtcaaatgg ccaaccactg ttccagcttc aagtggtgct gggattgctt tggaatcagg
     8221 tgtgaattga acagattggg aagattgatt cccaacacgt tcgattagat agatatcctc
     8281 tggagccact gcagttactg tatcttcttt tccatcttgt acaggggctt tgctatcttg
     8341 ataggcatcg ccttgttgaa cgattttgcg aagtgtaaat gtagaagaaa tataatccat
     8401 tagggaagat gtagctgtaa atcgagcgta aggattattg tcttgatgat ctgcatttaa
     8461 aacaactgtg atgactctca tgcctttttc gacagtagta ccaacaaaag actctccagc
     8521 cttatctgtt gttcctgttt ttagcccatc aaaaccacca cggtaagcag gcataccttc
     8581 taacatgtag ttggttgaag tgattgtcat cccagcaaaa gtagaagaag gttttttggt
     8641 gatttctaag acttgtgggt attttttgat gaggttgcga gcaacgatag cgacatcata
     8701 agcactaagc ttattttcct catctttttt agaacctggg taaatgttat cccctagagt
     8761 ttcattgtta agacctgtcg tattgacaac agtggcatcc tgaattcccc attccaagag
     8821 ttttgcccgc atcatatcga cgaaatcttt ttctgagcca gcaattttct cagctagggc
     8881 aatagcggcg ctgttggcac tagataccag agttgcttca agcaactctt cgacagtata
     8941 attacgggcc tccataggaa tattactggc ttcagaattt gtcgtcaatt gataaggata
     9001 atcagaaata tctacaggag tggagagggt aatacttccg ttttccaaag cttcatagac
     9061 cagataaaca gtaatcaatt ttgttatgga agcaatttcg acaggttgcg ttgcatcctt
     9121 ctcatagaga attttaccag tatttgcctc aacagcaatc gcatgtttag cggcaatggt
     9181 aaaatcttga gcaacagcag tagaagcacc ccctaaaaga gagacagtta acaaagttaa
     9241 aaatattttt ttcatagtag tcttattcta tcataaagaa aaaaaatatt cttgctttaa
     9301 taattcatct gttaagcttt ttgaaaatat ggtaaaataa agtgagggag gtaactcatg
     9361 tttcgtagaa ataaattatt tttttggacc acagaaattt tactcttaac catcatcttt
     9421 tacctatgga gacagatggg gtctttgatt aacccttttg ttagcgtgct taatacaatt
     9481 atgattccat ttttattagg gggctttctt tattatttga caaaccctat tgttactttc
     9541 ttaaataaag tctgtaaact caatcgtttg cttggtattt taattacctt gtgtactttg
     9601 gtctggggaa tggtcatagg tgttgtctat ctcttaccta ttttgattaa tcagttatct
     9661 agtttgatta tatctagtca aactatttat agtcgaatac aagacttaat catagactta
     9721 tctaattatc ctgcgctcca gaatttggat gtagaagcta caattcagca gttaaactta
     9781 tcctatgttg atattcttca aaatatccta aatagcgtat caaatagtgt ggggagcgtc
     9841 ttgtcagctc ttatcagtac tgttttgatt ttgattatga ctccagtttt tttggtttat
     9901 ttcttattag atggacataa attcttgccc atgcttgaaa gaacgattct aaagagggat
     9961 cgcttgcata ttgcaggctt attaaagaat ttaaatgcga cgattgctcg ctatattagt
    10021 ggagtttcga ttgacgcaat cattataggt tgtttagctt atattggcta tagtattatt
    10081 ggtttaaaat atgctttagt ttttgccatt ttttctggtg tagccaattt aattccttat
    10141 gtggggccaa gtattggttt gattcctatg atcatcgcaa atatattcac tgatcctcat
    10201 agactgctga ttgcagtgat ttatatgctt gttgttcagc aggtagatgg caatatctta
    10261 tatcctcgaa tcgtaggaag tgttatgaag gttcatccaa tcacgatttt agttttactt
    10321 ttgttgtcaa gcaatatcta tggtgtagtt ggaatgattg tcgcagtgcc aacctattct
    10381 atcttgaaag aaatttctaa gttcttatcc cgtttgtatg aaaatcataa aataatgaaa
    10441 gaacgagaaa gagaattagc taagtaaaag tcaggagaac cctgattttt ctttactgga
    10501 agtggccttt agattagaag actgaaaata agttaaagtc ttaaactaat tttcacagct
    10561 aagaatagta gaagttaatc tgataaaaat cgaaaaaacc agtggaattc tgtgtcaggg
    10621 taagttccac tggttttcat agtctattaa agttcgaatg aaacctattt atagtatatt
    10681 gaaactagaa tagtacacct ctaattctaa aacattgtta gaaatcgatt tgactgtcct
    10741 aatctattcg tcctattctt atttcatttt actatatttt ggtgcaataa gtgaaaagta
    10801 gtccgaataa tataaggatt gattttatag tttttaaact caaatgaatt aaaataaaga
    10861 gagtacgaaa attctcatct gaaagtattt tagaataatt ctcttcgtga atttcttcaa
    10921 aacagatagc ttcatcttag gtatgtgtta attggatttc gtaagctcta tttacaatcg
    10981 taaagttatg cactgagaaa gttgtagtta gtcttccagt ttgctaaatt tctcgaatag
    11041 tatctttttt aggtatgtga tttctttttg catttttgag ttagataagg tataatagtt
    11101 ttattgtctt ttggggtcgt tacggattcg acaggcatta tgaggcatat tttgcgactc
    11161 gtgtggcgac gtaaacgctc agttaaatat aactgcaaaa aataacactt cttacgctct
    11221 agctgcctaa aaaccagcag gcgtgacccg atttggattg ctcgtgttca atgacaggtc
    11281 ttattattag cgagatacga ttaagccttg tctagcggct tgataagaga ttgatagact
    11341 cgcagtttct agacttgagt tatgtgtcga ggggctgtta aaataataca taacctatgg
    11401 ttgtagacaa atatgttggc aggtgtttgg acgtgggttc gactcccacc ggctccatta
    11461 ttcctttgca ttcttttgca ttccttggta aaacgttgtt aaatcaacgt tttttatttt
    11521 tatatttggt attcctttgc attcttttgc taaaaaggga gtcacaaaca gaccctattt
    11581 taaaaaagga tacaacattt gtcgcatcct aaaaataatc ttttttcgac ggaagacatg
    11641 ggattcgaac ccacgcacgc tattacacgc ctaccgcgtt tccaacacgg cctcttaagc
    11701 ctcttgagta atcttccaat acttactcaa atagtctacc ataaaggctc ttatcttgca
    11761 ataaaaattc tagaaataag aaaaatgata gattttgaaa gaaaatgaca aaaaatgctt
    11821 gacttcgaaa taaagtatgg tagaatgaat agtgtaaacg ataacaggag gtgattcagt
    11881 gttaaaaaca gaacgtaaac aactgatttt agaggagtta aatcaacatc atgtagtttc
    11941 tctagaaaaa ttagttagtt tgctagaaac gtcagaatca acggttcgaa gagacttgga
    12001 tgagttggaa gcggaaaaca agcttcgtcg tgtgcatggt ggagcagaac tcccccactc
    12061 cttacaggaa gaagaaacca ttcaagaaaa atctgtcaaa aaccttcaag aaaagaagtt
    12121 gctggctcag aaagcagcct ctctcattaa agaaaaagat gtcatcttta tcgatgctgg
    12181 aacaacaact gcttttttga ttcatgaatt ggtcaataag aatgttacag ttgtgaccaa
    12241 ctccattcac catgctgctc agttggttga aaagcagatt ccaactgtca tggttggagg
    12301 aaacgtcaag acggcgacag atgctagtat cgggggcgtt gctcttaacc agattaacca
    12361 attgcacttt gaccgtgcct ttatcggaat gaatggtgtt gacgatggct attatacgac
    12421 tcctgatatg gaggagggag ctgtgaaaag agctattttg gagaatgcca agcagaccta
    12481 cgtcttggtg gattcgtcaa aaattggaca aacttgcttt gccaaggtag caccactcaa
    12541 acgcgctatc gttatcacta gtcaagggca tgagctcttg caggttatta aggagaaaac
    12601 ggaggtaata gaagtatgat ttatacagtc acactcaatc catccattga ctatatcgtt
    12661 cgtttggacc aagtcaaagt tggtagtgta aatcgtatgg acagtgatga taagtttgct
    12721 ggtgggaaag gaatcaatgt cagccgtgtc ttgaaacgtt tgaatatacc aaatacagcg
    12781 acgggattta tcggtggctt tactggtaaa tttatcacag atactttagc agaggaagaa
    12841 atcgagacac gttttgtcca ggtggcagaa gatactcgta tcaatgttaa aatcaaagca
    12901 gaccaagaaa cagaaatcaa cggaacgggt ccaactgttg aaccggttca gctagaagaa
    12961 ttgaaagcta ttttatctag tctgacagca gaagatacag ttgtctttgc aggttcaagt
    13021 gctaaaaatc taggcaatgt tatctataag gatttgattt ccttgacgcg ccagactggt
    13081 gcgcaagtgg tctgtgactt tgaaggacag accttaattg atagtttgga ctaccagcct
    13141 cttcttgtaa aaccaaacaa tcatgaactt ggagcgattt ttggggttaa actcgaaagt
    13201 ttagatgaaa ttgagaaata cgctcgtgag ttactggcta agggtgctca aaatgttatt
    13261 atctctatgg ctggtgatgg cgcccttctt gtcacatctg agggagctta cttcgctaaa
    13321 ccaatcaaag gaacagtcaa aaattcagtt ggagctggtg attctatggt tgctggattc
    13381 acaggtgaat ttgtcaaatc aaaagacgca gtagaagcct tcaaatgggg agtggcttgc
    13441 ggaacggcaa ctaccttctc agatgacttg gcaacggcgg aatttattaa agaaacatat
    13501 ggaaaagttg aggtagaaaa aagatgaaaa ttcaagacct attgagaaaa gatgtcatgt
    13561 tgctagattt gcaggcaact gaaaaaacag ctgtcatcga cgagatgatt aaaaatttga
    13621 cagagcacgg ttatgtaaca gattttgaaa catttaaaga aggaattttg gcgcgtgaag
    13681 ctttgacttc tactggtttg ggtgatggaa tcgcaatgcc tcacagcaaa aacgctgctg
    13741 tcaaagaagc gacagttcta tttgctaagt caaataaggg tgttgactac gagagcttgg
    13801 atggacaagc aactgacctc ttcttcatga ttgcagctcc agaaggtgcc aatgatactc
    13861 acttggcagc cttggcagaa ttgtctcaat acttgatgaa agacggtttt gcagacaaac
    13921 ttcgtcaagc aacatctgca gaccaagtta tcgaactttt tgaccaagct tcagaaaaaa
    13981 ctgaggaact tgttcaagca cctgctaatg actctggtga ctttatcgta gctgttacag
    14041 cttgtacaac aggtattgcc cacacttaca tggcccaaga agcccttcaa aaagtagctg
    14101 ctgaaatggg ggttggtatc aaggtcgaaa ccaacggtgc tagcggtgtt ggaaatcaac
    14161 taactgcaga agatatccgt aaggctaaag ctattatcat tgcagcagac aaggccgttg
    14221 aaatggatcg atttgatgga aaaccattga tcaatcgtcc agttgctgac ggtatccgta
    14281 agacagaaga gctaattaac ttggctcttt caggagatac tgaagtctac cgtgccgcta
    14341 atggtgccaa agctgcaaca gcctctaacg aaaaacaaag ccttggtggt gccttgtaca
    14401 aacacttgat gagtggtgta tctcaaatgt taccattcgt tatcggtggt ggtatcatga
    14461 ttgcccttgc cttcttgatt gacggtgctt tgggtgttcc aaatgaaaac cttggcaatc
    14521 ttggttctta ccatgagtta gcttctatgt tcatgaaaat tggtggagct gcctttggtt
    14581 tgatgcttcc agtctttgcg ggttatgttg cctactctat tgctgaaaaa ccgggtttgg
    14641 tagcaggttt cgtggctggt gctattgcca aagaaggttt tgcctttggt aaaattcctt
    14701 atgccgcagg tggtgaagca acttcaactc ttgcaggtgt ctcatctggt ttcctaggtg
    14761 cccttgttgg tggatttatc gcaggtgcct tggttcttgc catcaagaaa tacgttaaag
    14821 ttcctcgttc actcgaaggt gctaaatcaa tccttctatt gccacttctt ggaacaatct
    14881 tgacaggatt tgttatgcta gctgtgaata tcccaatggc tgcaatcaac actgctatga
    14941 atgacttcct aggcggtctt ggaggaggtt cagctgtcct tcttggtatc gtccttggtg
    15001 gaatgatggc tgttgacatg ggtggaccag ttaataaagc agcttatgtc tttggtacag
    15061 gtacgcttgc agcaactgtt tcttcaggtg gttctgtagc catggcagca gttatggctg
    15121 gaggaatggt gccaccactt gcaatctttg tcgcaactct tcttttcaaa gataaattta
    15181 ctaaggaaga acgtaactct ggtttgacaa acatcatcat gggcttgtca tttatcactg
    15241 agggagcgat tctatttggt gccgctgacc cagctcgtgc gattccaagc ttcatccttg
    15301 gttcagcagt agcaggtgga ctcgttggtc ttactggtat caaactcatg gcgccacacg
    15361 gaggaatctt cgttatcgcc cttacttcaa atgctctcct ttacctcgtt tctgtcttgg
    15421 taggagcaat cgtaagtggt gtggtttatg gttacctacg caaaccacaa gcataaaaaa
    15481 tagaaaaatg aaaagattgg accgtttggt gcagtctttt tctcttcccg aaatgcctgt
    15541 gaaatatggt ataatagaag aatggcaaac aagaatacaa gtacaacaag acggagaccg
    15601 tctaaagcag aactggaaag aaaagaagcg attcaacgaa tgttgatttc gttaggaatt
    15661 gcgattttat tgattttcgc agccttcaaa ttaggggctg caggtataac cctttataat
    15721 ttaattcgct tgctagtggg tagcctagct tatctggcga tattcggcct attaatctat
    15781 ctcttctttt tcaagtggat acgaaaacag gaaggactct tatctggctt tttcaccata
    15841 tttgctggct tactcttgat ttttgaggcc tacttggttt ggaaatatgg tttggacaag
    15901 tccgttctaa aagggaccat ggctcaggtt gtgacagatc tgactggttt tcgaacgact
    15961 agctttgctg gagggggctt gatcggggtc gctctttata ttccaacagc ctttctcttt
    16021 tcaaatatcg gaacttactt tattggttct atcttgattt tagtgggttc tctcctagtc
    16081 agcccttggt ctgtttacga tattgctgaa tttttcagta gaggctttgc caaatggtgg
    16141 gaagggcacg agcgtcgaaa agaggaacgc tttgtcaaac aagaagaaaa agctcgccaa
    16201 aaggctgaga aagaggctag attagaacaa gaagagactg aaaaagcctt actcgatttg
    16261 cctcctgttg atatggaaac gggtgaaatt ctgacagagg aagctgttca aaatcttcca
    16321 cctattccag aagaaaagtg ggtggaacca gaaatcatcc tgcctcaagc tgaacttaaa
    16381 ttccctgaac aggaagatga ctcagatgac gaagatgttc aggtcgattt ttcagccaaa
    16441 gaagcccttg aatacaaact tccaagctta caactctttg caccagataa accaaaagat
    16501 cagtctaaag agaagaaaat tgtcagagaa aatatcaaaa tcttagaagc aacctttgct
    16561 agctttggta ttaaggtaac agttgaacgg gccgaaattg ggccatcagt gaccaagtat
    16621 gaagtcaagc cggctgttgg tgtaagggtc aaccgcattt ccaatctatc agatgacctc
    16681 gctctagcct tggctgccaa agatgtccgg attgaagcac caatccctgg gaaatcccta
    16741 atcggaattg aagtgcccaa ctccgatatt gccactgtat ctttccgaga actatgggaa
    16801 caatcgcaaa cgaaagcaga aaatttcttg gaaattcctt tagggaaggc tgttaatgga
    16861 accgcaagag cttttgacct ttctaaaatg ccccacttgc tagttgcagg ttcaacgggt
    16921 tcagggaagt cagtagcagt taacggcatt attgctagca ttctcatgaa ggcgagacca
    16981 gatcaagtta aatttatgat ggtcgatccc aagatggttg agttatctgt ttacaatgat
    17041 attccccacc tcttgattcc agtcgtgacc aatccacgta aagccagcaa ggctctgcaa
    17101 aaggttgtgg atgaaatgga aaaccgttat gaactctttg ccaaggtggg agttcggaat
    17161 attgcaggtt ttaatgccaa ggtagaagag ttcaattccc agtctgagta caagcaaatt
    17221 ccgctaccat tcattgtcgt gattgtggat gagttggctg acctcatgat ggtggccagc
    17281 aaggaagtgg aagatgctat catccgtctt gggcagaagg cgcgtgctgc aggtatccac
    17341 atgattcttg caactcagcg tccatctgtt gatgtcatct ctggtttgat taaggccaat
    17401 gttccatctc gtgtagcatt tgcggtttca tcaggaacag actcccgtac gattttggat
    17461 gaaaatggag cagaaaaact tcttggtcga ggagacatgc tctttaaacc gattgatgaa
    17521 aatcatccag ttcgtctcca aggctccttt atctcggatg acgatgttga gcgcattgtg
    17581 aacttcatca aggctcaggc agatgcagac tacgatgaga gttttgatcc aggtgaggtt
    17641 tctgaaaatg aaggagaatt ttcggatgga gatgctggtg gtgatccgct ttttgaagaa
    17701 gctaagtctt tggttatcga aacacagaaa gccagtgcgt ctatgattca gcgtcgttta
    17761 tcagttggat ttaaccgtgc gacccgtctc atggaagaac tggagatagc aggtgtcatc
    17821 ggtccagctg aaggtaccaa acctcgaaaa gtgttacaac aataaaaaaa tagcttcttt
    17881 ccgagtttgg agggaagcta ttttagtggc tattgattgc ttttattttc tgaagttggc
    17941 gcattggact gtttttcgtt ttcagtagca ggtttacttg aagcaggagt agaagagtcc
    18001 tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt tggtgtttcc
    18061 tcttgctgtg ttttttcttg actagtgtta gtctctttag ttggactggt gttttcctta
    18121 ggggattcct tttggatttc tttgacaatg gttgtcgtct ggcttgtcgt aggttctttt
    18181 ttaatatttt tgttattatc caaggcgttc atgatcgtga tacccgcggt aatcaagcca
    18241 aggatactag cgattgtagc aacggttttt tgaaagactg taaagccttt tttgatgtgt
    18301 tctgtttttg gttttgaagt tctacgatag ttagacatac attctctcct ttgattatga
    18361 tttattatac tctgtttctt taaaaaaatc ttaaaaaaag agaaattgcc ctttcttgtc
    18421 gcaggctccg tttcatgata caatagaagg agtgatttta gaaagcgtga gaaacatgat
    18481 ttactttgat aattcggcga cgaccaggcc ctatccagaa gcccttgaaa cctatatgca
    18541 ggtggcttca aaaattttag gaaatccatc tagtctccat cgtttgggag accaggcaac
    18601 acgaatttta gatgcttccc gtcaacagat tgcagattta atcggtaaga aaagtgatga
    18661 aatcttcttt acatctggtg ggacagaagg ggataactgg atcatcaagg gagtagcatt
    18721 tgaaaaagcc cagtttggca agcacatcat cgtatcagcc attgaacatc cagcagttaa
    18781 ggaatcagcc ctctggttga aagctcaagg ttttgaagtg gattttgctc cagttgataa
    18841 caaaggattt gtggatgttg aggcgctaga agatttgata agacctgata cgaccctcgt
    18901 ttccatcatg gcagttaaca atgaaattgg ctctgttcag cccattgagg ctatttcaaa
    18961 actattggca gacaagccaa ctatttcctt ccacgttgat gcggttcagg cgcttgccaa
    19021 gattccgact gaaaagtatc tgacagaacg ggtggattgc gcgaccttct cgagtcataa
    19081 atttcatggt gtccgtggtg ttggctttgt ctatatcaaa tctggcaaga agattactcc
    19141 tcttttaaca ggtggtggtc aggaacgtga ttaccgttcg acaactgaaa atgtggcagg
    19201 aattgcagcg acagccaagg ccctccgttt atctatggaa aagctagata tctttaggag
    19261 caagactggg cagatgaagg cagtgattcg tcaagcactt ctggactatc cggatatatt
    19321 tgtcttttca gatgaggaag acttcgcccc tcatattctg acttttggaa tcaagggtgt
    19381 tcgtggtgag gtcattgttc acgcctttga agactatgat attttcatct caacgacctc
    19441 ggcttgttcg tccaaggctg ggaaaccagc cggaaccctg attgctatgg gagtggacaa
    19501 ggataaggct cagtcagctg tgcgtcttag tctagacctt gaaaatgata tgagtcaggt
    19561 cgagcagttc ttgaccaagc taaaattaat ttacaatcaa actagaaaag taagatagga
    19621 gcattcatgc agtattcaga aattatgatt cgctacggtg agctgtcaac caagggcaaa
    19681 aatcgtatgc gtttcatcaa taaacttcgc aataatattt cagacgtttt gtctatctat
    19741 ccccaagtta aggtaacagc agatcgcgac cgtgcccacg cttacctcaa tggagcagat
    19801 tacacagcag tagcagaatc gctcaaacaa gtatttggaa ttcaaaactt ttcccctgtt
    19861 tataaggttg aaaaatctgt agaagttctg aagtctgctg tccaagagat tatgcaggac
    19921 atctacaagg aaggcatgac ctttaaaatc tctagcaagc gtagcgacca cacctttgaa
    19981 ttggacagtc gtgaactcaa ccaaacgctt ggaggggctg tattcgaagc cattccaaac
    20041 gtacaagctc aaatgaaaag tcctgacatc aatcttcagg tggagatacg tgaagaagca
    20101 gcctatcttt cttatgaaac cgttcgaggg gcaggtggat taccagtggg aacttctggt
    20161 aagggcatgc tcatgttgtc agggggaatc gattcccctg tagctggcta tctagcgctt
    20221 aaacgagggg tagatataga ggcagttcac tttgccagcc caccttacac gagtcctggt
    20281 gctcttaaaa aagcccaaga tttgacccgt aaattaacca aatttggggg aaatatccag
    20341 tttatcgaag ttccttttac agagattcaa gaggaaatca aagccaaagc gccagaagcc
    20401 taccttatga ccttgacgcg tcgttttatg atgcgtatta ctgaccgtat tcgtgaggta
    20461 cgaaatggtt tagttatcat caatggggaa agtctaggtc aagtagccag ccaaaccctt
    20521 gaaagtatga aggctatcaa tgctgttacc aacactccca tcattcgtcc tgtggttacc
    20581 atggacaagt tggaaatcat tgacatcgcc caggaaatcg atacctttga catttcaatc
    20641 caaccgtttg aagactgttg taccattttt gcaccagatc gtccaaaaac aaatcctaaa
    20701 attaagaatg cggagcagta cgaagcgcgt atggatgttg aaggcttggt tgagcgagca
    20761 gtggctggaa tcatgattac tgaaatcaca cctcaagccg aaaaagatga agttgatgac
    20821 ttgattgaca atctgctcta attcagaaaa tccaaaagaa tagcgaaaat cagtaaaaaa
    20881 agttagtttt ttctctaaaa acaggtaaaa aactaacttt ttttattttt atgatataat
    20941 gatataaaat tttgaatata gagagttttc tgacaatgaa tcaatcctac ttttatctaa
    21001 aaatgaaaga acacaaactc aaggttcctt atacaggtaa ggagcgccgt gtacgtattc
    21061 ttcttcctaa agattatgag aaagatacag accgttccta tcctgttgta tactttcatg
    21121 acgggcaaaa tgtttttaat agcaaagagt ctttcattgg acattcatgg aagattatcc
    21181 cagctatcaa acgaaatccg gatatcagtc gcatgattgt cgttgctatt gacaatgatg
    21241 gtatggggcg gatgaatgag tatgcggctt ggaagttcca agaatctcct atcccagggc
    21301 agcagtttgg tggtaagggt gtggagtatg ctgagtttgt catggaggtg gtcaagcctt
    21361 ttatcgatga gacctatcgt acaaaagcag actgccagca tacggctatg attggttcct
    21421 cactaggagg caatattacc cagtttatcg gtttggaata ccaagacaaa attggttgct
    21481 tgggcgtttt ttcatctgca aactggctcc accaaccgct atatcgagtg ccagaaacta
    21541 tcgcctgacc aacgcatctt catctatgta ggaacagaag aagcagatga tacagacaag
    21601 accttgatgg atggcaatat caaacaagcc tatatcgact cgtcgctttg ctattaccat
    21661 gatttgatag cagggggagt acatctggat aatcttgtgc taaaagttca gtctggtgcc
    21721 atccatagtg aaatcccttg gtcagaaaat ctaccagatt gtctgagatt ttttgcagaa
    21781 aaatggtaag ttaagaaagg aaaaaacgaa atgcatattg aacatcttag ccactggagt
    21841 ggtcatccta accgtgaaat gtaccttaac cgttatggac atggtgggat tccagttgtg
    21901 gtctttgctt catcaggtgg tagtcacaac gaatactatg attttggcat gattgatgcc
    21961 tgtgcttcct ttatcgagga aggccgtgtc cagttcttta ccctatctag tgtggatagt
    22021 gagagctggt tggctacttg gaaaaatgct catgaccaag cggaaatgca ccgtgcctac
    22081 gaacgttatg tgattgagga ggccattctt ttatcaagca caagacaggt tggtttgatg
    22141 gcatgatgac gacaggttgc tctatgggag cctatcatgc actcaatttc ttcctccagc
    22201 atccagatgt ctttaccaaa gtgattgctc tcagtggtgt ttacgacgca cgtttctttg
    22261 tcggtgatta ctacaacgat gatgctattt accaaaactc gccagtagat tatatttgga
    22321 actaaaacga cggctggttt attgaccgtt accgtcaggc agagattgtg ctgtgtacgg
    22381 ggcttggagc ctgggaacaa gatggtttgc catcctttta caagctcaaa gaagcctttg
    22441 acaagaaaca aattccagcc tggtttgctg aatggggaca tgatgtcgcc catgactggg
    22501 aatggtggcg taaacaaatg ccttatttcc tcggtaatct ctatttataa aaggagttac
    22561 ctatgaatta ccttgttatt tctccctact atccacaaaa ctttcaacag tttaccatcg
    22621 aactagctaa taaaggcatc acagtcttgg gaattggtca agagtcttac gagcaattgg
    22681 atgagccctt gcgcaatagc ttgaccgagt attttcgtgt tgataatctt gagaacatag
    22741 atgaagtcaa acgtgcagtt gcttttctct tttataaaca tggtccaatt ggccgcatcg
    22801 agtctcacaa tgaatactgg cttgagctag acgcaacact cagagaacaa ttcaatgttt
    22861 ttggtgccaa accagaggat ctcaaaaaga cgaaatataa gtctgaaatg aagaaacttt
    22921 tcaaaaaagc aggtgttcct gtggtacctg gagctgttat caagacggaa gcagatgttg
    22981 atcaagcagt gaaagaaatc ggtcttccaa tgattgccaa acctgataat ggagtgggag
    23041 cagccgcaac ctttaaactt gagacagaag acgatatcaa tcacttcaag caagaatggg
    23101 accattcaac cctttatttc tttgaaaaat ttgtcacttc cagcgaaatc tgtacctttg
    23161 acgggctcgt ggacaaggat ggaaagattg tcttctcaac aacctttgac tacgcctata
    23221 caccgcttga cctcatgatt tataagatgg acaattctta ttatgtgctc aaggatatgg
    23281 atcctaaact gcgcaagtat ggggaagcaa ttgtcaaaga atttggtatg aaagaacggt
    23341 ttttccatat tgagttcttc cgtgaggggg acgattatat taccattgag tacaataacc
    23401 gccctgcagg tggtttcacc attgatgttt ataactttgc tcattccttg gacctctatc
    23461 gtggatatgc agccattgtc gcaggagaag agttcccagc gtcagacttt gaacctcagt
    23521 attgtttggc tacatcacgt cgtgcaaatg ctcactatgt ctattctgag gagaacttac
    23581 ttgccaaata tagccagcag ttcaaggtta aaaaaatcat gccagaggct tttgcggaac
    23641 ttcaaggaga ttacttttat atgctgacaa ctccgagtcg acaagaaatg gatcagatga
    23701 ttgctgattt cggacaacgt caagaataag aactatcgga ttaaggaaat tcactccctt
    23761 aatccttttg ttttgtctgg taaaaaataa gagcatccta acaaggtagc tatcataaaa
    23821 cttgttcgat aactatttga agcaggatta ggttgctcaa aacactgttt tgaggttgtg
    23881 gatagaactg acagagtcag tatcatatac ctacggcaag gtgaagctga cgtggtttga
    23941 agagattttc gaagagtata aaatattcag gtgacgcata gatatagtta attgaagctt
    24001 tgtttgaaat ctgataaaat aatgatatta ctaagtttta aaaactaaag aaaagggaag
    24061 atatgattac aggcgaatta aaaaataaaa tcgatcagct gtgggaaatt ctttggacag
    24121 aaggaaacgc aaatccttta acaaatattg aacagttgac ttatctctta tttatgaaag
    24181 atttggatag tgtcgagctt ggacgtgaaa gtaatgctga atttctaggg attccttatg
    24241 agggagtttt tccaaaagat aaacctgaat accgttggtc aacttttaaa aatataggag
    24301 atgctcagga agtttatcgt ttaatgactc aggagatttt tccgtttatt aaaaatctca
    24361 agggggatac agatgataca gccttttcac gatatatgcg agaagctatt tttcaaataa
    24421 ataaacctgc tacgcttcaa aaggcaattt ctatcttaga tgtttttcca actaggggat
    24481 tagatgtaga ttttgataat gacaaacaaa gtattactga tatcggagat atctatgaat
    24541 atctgttatc aaaattgtcg accgcaggta aaaatggaca gttccgtaca cctcgtcaca
    24601 tcatcgatat gatggttgag ttgatgcaac cgactatcaa agatatcatc tcagatcccg
    24661 ctatgggttc tgctggcttc ttagtatctg ctagccgtta cttaaagcgt aagaaagatg
    24721 aatgggaaac caatacagat aatatcaatc attttcataa tcagatgttt catggaaatg
    24781 atacggatac gactatgttg agacttgggg cgatgaacat gatgctacat ggagtagaaa
    24841 atccacaaat cagttacctt gactcgctgt ctcaagataa tgaagaagct gataaatata
    24901 ctttggtttt agcaaatcct ccttttaagg gctcacttga ctacaattca acctctaatg
    24961 accttcttgc aaccgtaaaa accaaaaaaa cagaattact ctttctttct cttttcttgc
    25021 gaactttaaa accaggtgga cgagcagcag ttatcgtacc tgatggtgtc ctttttggtt
    25081 cgtctaaagc tcataaagga attcgtcagg aaattgtaga gaatcataag cttgatgctg
    25141 taatctcaat gcctagtggt gtgttcaagc cttatgctgg agtttcaact gccattctca
    25201 tctttacaaa aactggtaat ggtggtactg acaaagtctg gttttacgat atgaaagcgg
    25261 atggtttaag tttggatgat aagcgacaac cgattagaga caatgatatt ccagatatta
    25321 tcgaacgctt tcatcatctt gaaaaagaag cagaacgtca gagaacggat caatctttct
    25381 ttgttccagt tgctgagata aaggaaaatg attatgattt gtctatcaat aaatataaag
    25441 agattgagta tgaaaaagtt gagtatgaac caacagaagt catattaaag aaaatcaatg
    25501 atttagaaaa agaaattcaa gctggcttgg ctgaattgga aaaattactc aagtagggag
    25561 gtggctgtat gaaaaaagtg aagttggggg aagtcttatc tctaaaaaaa ggcaagaaag
    25621 ccactgtact tgctgaacaa acaactctaa gccaacgtta tattcaaata gatgatttaa
    25681 gaaataataa taatttaaaa ttcactgaaa gtttaaatat gactgaagca cttccagatg
    25741 atattctaat agcatgggat ggtgctaatg caggaacagt tggttatgga ttatcgggag
    25801 ctgttggtag tacaattacg gtcttaaaaa agaatgagcg atacaaagaa aaaattatat
    25861 cagattactt gggagtcttt ttggaaagta aatcgcagta tttacgagat cattcaacag
    25921 gtgcaactat tcctcattta aacaagaata tattacttga tttacaatta gaattgctag
    25981 gtatcgaaga acaagagaac attatctgta ttcttaatac gattaaaagg cttattacta
    26041 aaagaaaatt tcagttagat gaactaaact tgctcgtcaa atcccgattt aacgagatgt
    26101 ttggggaaaa taaaatattt gaaagcattg ataacttatt tgatattata gatggtgata
    26161 ggggcaaaaa ttatcctaaa tcagatgagt tgtttagtga ggagtactgt ttatttttaa
    26221 atacaaagaa tgttactaaa aacggatttt cattcgatac aaagcaattt atcactaaaa
    26281 caaaggataa attacttcga aaaggcaaac ttgagcgtta tgatatagtc ttgacaacaa
    26341 gaggtactgt tggaaatgta gcgtactacg atgaattaat aaaatataaa catttacgta
    26401 taaattcagg tatggtaata ttacgtccca agacaccaaa tcacaatttg cttgtgagat
    26461 agctataaaa gtgtggagaa atagcttgaa atttagtata atatagctaa actatttgtt
    26521 taaagtgaga aaaaaatggg aaattttagc tttcttttaa aaaatgacga atatgaatct
    26581 ttttcaaaac cttgcattga agctgagaat atgattgcta catcaactgt ggctactgcc
    26641 tttatggcgc gtcgtgcttt agagcaggct gtccattgga tatatagtca cgattcatat
    26701 ttagaagctc cctatcgtgc tactctatct tctttagtat gggatgatga ttttagggat
    26761 atcgtagatt ctgaactcca caagcagata gttctgttga ttcggtgggg aaaccatgct
    26821 gctcatggtg gtgaaattaa ggaacgagaa gcgattttag ctttgcatca tttgtatcag
    26881 tttgttaatt ttatcgatta ttgttacagc aatgagtttg tggagcgtta ttttgatgag
    26941 aagtgcttac cactttcagc aaacatcaaa taccgagaaa ctccacaatc tatgataaag
    27001 ttacaagaca gtttaccaga actgcctgat tttcatgaac agatggctgc tcagtccgta
    27061 gaagttcaag agacttatac tgaaaaacgt gagactgcag cgcaacggca agatgtgcct
    27121 ttccatattg atcaattatc tgaggcagag acaagaaagc tctttattga tatcgatctc
    27181 cgtttagcag gatggatatt tgaagaaaac tgtcgtgttg agatagccgt tgatggtctc
    27241 aagcacggtt caggaattgg ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt
    27301 ttagcgattg tggaggctaa aaaagcctct gtcaatccag aagtagggga agtacaggtc
    27361 aaagaatatg ctgaagcttt ggagaaacat atcggctatc agccaatttg ctttattaca
    27421 aatgggttga agcactatat acttgatggt ccgaaccgcc gccagattgc aggcttttac
    27481 tctcaagaag aattgcaatt agtgatggat agacgtcatc ttcaaaaacc gcttgaggat
    27541 atttctagta aaattaggga cgatatttcc gggcgtcact accaaaaaca tgccattgca
    27601 agcgtttgtg aagctttctc taatcatcgt agacaggcac ttttggttat ggcaactggg
    27661 gctgggaaaa ctcgtacagc agtttctcta gttgatatct tatcacgtca taactgggta
    27721 aaaaacgttc tcttcttagc cgatagaact tccttggtta agcaagcata tgattcgttt
    27781 agaaaattac tcccagatct ttccgtttgt aacttcttag aagataaaga aggagctcaa
    27841 tcaagtcgca tggtcttttc aacttatccg accatgattg gagcgattag tggtcaagaa
    27901 gaagtaaatc aacgcccttt cactgttggg cattttgacc ttatcataat tgacgaatct
    27961 caccgttcta tttatcagaa atacaagtcc atttttgatt attttgatgc aagaattgta
    28021 ggcttaacag ctactccgcg tcaagattta gataaaaaca cctatggatt ctttaatttg
    28081 ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag acggatattt
    28141 agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc tacattatga
    28201 tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg atagctgtga
    28261 aaaagatatt gatgggagtg tatttaattc ctttattttc aataaaagta cagtagaaat
    28321 tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg aaattggtaa
    28381 aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta tttttaacaa
    28441 ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta ttaagcatta
    28501 tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg cgatttctgt
    28561 cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct tcttcaagaa
    28621 agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc tatgtaaaga
    28681 tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg gggacaattt
    28741 tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt cgctgactca
    28801 gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc aataccaaga
    28861 agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag gtcgtataga
    28921 gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt atagctatag
    28981 gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc aaaaaaatct
    29041 ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat ttgatttgtg
    29101 gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc atatttccca
    29161 agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg tttttgagca
    29221 ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta acttgtctga
    29281 tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata aaacagaccg
    29341 taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg agaccacagc
    29401 atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt atttgaaaac
    29461 tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga catctgatga
    29521 tatgcttgca cttgaaaaat tgctttggga aaaattaggt agtaaagcag actaccaaag
    29581 tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct tagatagaga
    29641 gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg ccaggcagat
    29701 ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag agacgaaagt
    29761 gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc aacaccaact
    29821 accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag ctggagaagc
    29881 ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa agagtagaaa
    29941 tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct agaatacagt
    30001 atcagttgtt aagtggttga taaatttcaa agtagatact tgtaccacga tgtttgttga
    30061 tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa aaagccgagc
    30121 aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag agcaaactag
    30181 gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga ctgacgaagt
    30241 cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta accataccta
    30301 cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat cttcctagga
    30361 taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt tttctgatgt
    30421 taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt tattattctt
    30481 caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg
    30541 catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga
    30601 agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta
    30661 ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac
    30721 gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc
    30781 ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg gttacttgaa
    30841 tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg ttttttgtga
    30901 taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt
    30961 tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg
    31021 tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct
    31081 tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta
    31141 atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg
    31201 actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga
    31261 ccgttgtcaa tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc
    31321 ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga
    31381 ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc
    31441 tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt actatagcgc
    31501 tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag
    31561 gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta
    31621 ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg
    31681 gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca
    31741 tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc
    31801 tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct
    31861 gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc
    31921 ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg agcttcattg
    31981 ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc aagggagtca
    32041 aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg
    32101 taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc
    32161 gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac ttttccgttt
    32221 gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcatg gcaacggccg
    32281 ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg
    32341 aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga
    32401 aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct
    32461 gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt ctctagctca
    32521 atcttgcgag gaagcttaac cttaagctcg ccctccatct tgtagagagc cttgtcacta
    32581 gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca
    32641 tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta
    32701 tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc
    32761 aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca
    32821 agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt
    32881 tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct
    32941 tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct
    33001 gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct
    33061 aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt
    33121 tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagctca
    33181 gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct
    33241 ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg gaattgttaa
    33301 cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata tagagaacag
    33361 agtaacaata agaataatag atagggtata aa
//
LOCUS       DAVKXA010000021        31750 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKXA010000021 DAVKXA010000000
VERSION     DAVKXA010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.021"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(171..1394)
                     /locus_tag="VW883_001042"
     CDS             complement(171..1394)
                     /locus_tag="VW883_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0274193.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1562..2884
                     /locus_tag="VW883_001043"
     CDS             1562..2884
                     /locus_tag="VW883_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0274194.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2886..4772
                     /locus_tag="VW883_001044"
     CDS             2886..4772
                     /locus_tag="VW883_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0274195.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4940..5284
                     /locus_tag="VW883_001045"
     CDS             4940..5284
                     /locus_tag="VW883_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0274196.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5294..6706
                     /gene="lacG"
                     /locus_tag="VW883_001046"
     CDS             5294..6706
                     /gene="lacG"
                     /locus_tag="VW883_001046"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0274197.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6776..8455
                     /locus_tag="VW883_001047"
     CDS             6776..8455
                     /locus_tag="VW883_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0274198.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8581..10020)
                     /locus_tag="VW883_001048"
     CDS             complement(8581..10020)
                     /locus_tag="VW883_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0274199.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10024..11373)
                     /gene="trkA"
                     /locus_tag="VW883_001049"
     CDS             complement(10024..11373)
                     /gene="trkA"
                     /locus_tag="VW883_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0274200.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEHDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11561..12409
                     /locus_tag="VW883_001050"
     CDS             11561..12409
                     /locus_tag="VW883_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0274201.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12424..12972
                     /locus_tag="VW883_001051"
     CDS             12424..12972
                     /locus_tag="VW883_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0274202.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            12979..13281
                     /locus_tag="VW883_001052"
     CDS             12979..13281
                     /locus_tag="VW883_001052"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274203.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            13383..15065
                     /locus_tag="VW883_001053"
     CDS             13383..15065
                     /locus_tag="VW883_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274204.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            15050..15880
                     /locus_tag="VW883_001054"
     CDS             15050..15880
                     /locus_tag="VW883_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0274205.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDISFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            16073..16576
                     /locus_tag="VW883_001055"
     CDS             16073..16576
                     /locus_tag="VW883_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0274206.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16630..16864
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            17029..17592
                     /locus_tag="VW883_001056"
     CDS             17029..17592
                     /locus_tag="VW883_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0274207.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17606..18232
                     /locus_tag="VW883_001057"
     CDS             17606..18232
                     /locus_tag="VW883_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0274208.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18260..18649
                     /locus_tag="VW883_001058"
     CDS             18260..18649
                     /locus_tag="VW883_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0274209.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            18654..19103
                     /locus_tag="VW883_001059"
     CDS             18654..19103
                     /locus_tag="VW883_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274210.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            19231..19818
                     /locus_tag="VW883_001060"
     CDS             19231..19818
                     /locus_tag="VW883_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0274211.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            20208..21815
                     /locus_tag="VW883_001061"
     CDS             20208..21815
                     /locus_tag="VW883_001061"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0274212.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            22146..26822
                     /locus_tag="VW883_001062"
                     /pseudo
     CDS             22146..26822
                     /locus_tag="VW883_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            26912..28108
                     /locus_tag="VW883_001063"
     CDS             26912..28108
                     /locus_tag="VW883_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0274213.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            28244..28771
                     /locus_tag="VW883_001064"
     CDS             28244..28771
                     /locus_tag="VW883_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0274214.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            28848..29204
                     /gene="glnR"
                     /locus_tag="VW883_001065"
     CDS             28848..29204
                     /gene="glnR"
                     /locus_tag="VW883_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0274215.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            29241..30587
                     /gene="glnA"
                     /locus_tag="VW883_001066"
     CDS             29241..30587
                     /gene="glnA"
                     /locus_tag="VW883_001066"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0274216.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(30683..30802)
                     /locus_tag="VW883_001067"
     CDS             complement(30683..30802)
                     /locus_tag="VW883_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0274217.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            31290..31750
                     /locus_tag="VW883_001068"
                     /pseudo
     CDS             31290..31750
                     /locus_tag="VW883_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         9706 a         5512 c         6953 g         9579 t
ORIGIN      
        1 tttataataa taaaatgcag ctagaagaaa agttatttta atataaatca ctcaacatag
       61 agagaaggcg gtttcctata tggaagtcgt cttgttttca tattgtctaa atacgagata
      121 tctactacag gttatagttg atttaaacag gtctatagat ttctaatata ttaaggtgaa
      181 ataatatctt gtaatacatt gctatgttct atgaaaaaag cgacgatagc taatgcacaa
      241 gctcctatac ttccacgatg tttgttgtaa ggtaaaattt caatttctat attacgagta
      301 aagggaacga agtggagctg gtcttggatt ttatccctga cttcatgagt gaaaggttga
      361 taattaagca attgactgtt gatatagatt ttatcagcag gattgatgag gaggagattt
      421 gcaatagaag tggctaataa attgactcct ttatcaattt gttgacgtaa agcggagtcg
      481 cctaaattat aagccgttaa aagggtgtct aaatgaatgt ctttttcagt ctttacaagg
      541 ctttttagta cagttagttg ggaattttta aataataatt gggcgtgttt gattaaccaa
      601 gcatccgaaa tatatgtttg taaacaacct ttttttccgc attcacaata ttgcccattc
      661 aattcgacaa tggtgtgtcc aatttctccg atataaggat ttttagaggc tcctattttt
      721 tcttttgtga aaaaggaagt gtaaatacct aatccagcgt gtaggaaaat aaagttatcg
      781 ggggtattgt gtggattaaa aaggtattgt cctatagcca tacaatcgat attatttttt
      841 acaataaaag gaaaattgaa tcttttaatt acatttaata aattaaaaga ttcccatatg
      901 gggttgtttg taatgatact tccggagtct ttgttataat gtccaggtat tgataagcca
      961 aatccaagta attttgtttc caaagggacg tactctatag ctgtttttat catattggta
     1021 atggtggaat tgatttctga aataggataa tcttcattca aaatttctgt ctcgaaaaga
     1081 gttttccctt gtaagtcaca tagactgaga aagataccta ggacgtttat ttcaatacct
     1141 ccaacaacat acggaatatt atctgtgata gaaatagttt ttctacgtct tccagatccg
     1201 gaaaactcgc taaattcatc accagtttcg tatatgaggg actgttcgct tagctctttt
     1261 atgatgttag tcgttgttgc tggagtaagt cctgtttcat taacaatatc tgtacgggat
     1321 gttgctggat ttcgatatag aaactccagt atagtggctc tattttgtaa aaaggctgat
     1381 tgttttgtaa tcatttgttt cctcctttgg tttattttat attaaacata agaaaaaatc
     1441 aattaaaatt attattctat acaaagaaaa aaatattgta aaaacaacaa aaaatatatt
     1501 gacaacgctt tctgttagtg gtatatttaa tttataaaaa ataaaaaaag gagttccggt
     1561 gatgaacaat attttagcgt ttttagaaac aaaagtcgct ccgtttggtg aaaaagttgg
     1621 caaccaacgg catttgaaag ctattcgtga aggatttatg atggcaatgc ctttgatttt
     1681 agtcggatct ttatttctta ttctaatcag ttggcctcaa gaggatttta caaattggct
     1741 gaatagtgtt ggattgctaa gtatcttgac aactatgaat cagtcaacag tagcgattat
     1801 ctccttggtc gcttgtttcg gtattgccta caggttgtcg gaaggatatg gtacagatgg
     1861 tccgtcggca gggatcatag ccttatccag ttttgtattg atggcacctc gtttttcgag
     1921 tatggtttat gataaaaatg gggagcaggt caagcagtta tttggcggcg caataccatt
     1981 ttctagcctg aatgcatctt ctttgtttat ggcgattact attggattgg ttacagcaga
     2041 gatttatcgt atgtttatcc agcgcggaat tacgataaaa atgccaagtg gtgtcccaga
     2101 tgtggtaagt aaatcatttt cagctctttt acctggcttt actacttttg ttttgtgggc
     2161 tttggtctta aaaggtcttg aagcggcagg agttgcagga ggtctcaacg gactcctagg
     2221 tgcaattgtt ggaacaccgc ttaagttaat tgcaggaacg cttccaggta tgattctatg
     2281 tgttattgta aactcattct tttggttctg tggagttaat gggggacaag ttttaaatgc
     2341 ttttgtagat ccagtttggt tacaatttac tacagaaaac caagaagctg tggctgcagg
     2401 acaaacactc caacacatta ttacattacc gtttaaagat ttatttgtat ttattggtgg
     2461 cggtggagcg actattggtc ttgcgatttg tctcttccta tttagtaaga gtcgtgcgaa
     2521 taaaacatta ggtaagctag ctattatacc gtctattttt aatatcaata cagctattct
     2581 atttacgttt ccaacagttt taaatccgat tatgctgatt ccgtttattg ctactcctac
     2641 aatcaatgcc ttgattacct atgtatcaat ggctgtagga ttagtaccct atacaacagg
     2701 tgtaatcctt ccgtggacaa tgccaccgat tataggaggc ttccttgcaa caggggctag
     2761 ttggcgagga gctctattac aagttgtttt gattttggtt tctgtagcaa tttattatcc
     2821 attcttcaaa attgcagata aacgcaatct tgaaaaagaa aaagctactg ttggagggaa
     2881 ataagatggt tatcagagta tttgatcaac agaaaaatac ttattctagc tttgccttag
     2941 aggaattaag ttactatatg aatcgggtct ttaagactaa catagagctt gtcgaggaga
     3001 aggaagcgga tatttttgta ggattagtca ataaagagga cagaaaagac catgttctta
     3061 tctcattaga caagggtaag ggaagaattg agtctaatac aattgtaggt ttacttattg
     3121 gaatttaccg aatgtttcat gaatttgggg ttgtgtatac tagaccaggg cgcagacatg
     3181 actttgttcc agagttacga tttgaagatt ttttagataa acagctatct atagatgaaa
     3241 cagccagtta ctatcatagg ggagtatgta tagagggagc ggattcattt gaaaatatac
     3301 tagatttcat tgattggcta cctaagattg ggatgaacag ttttttcatc cagtttgaaa
     3361 atccttactc ttttttgaaa cgttggtatg aacatgaatt taatccatat ctaaataaag
     3421 aacaattttc aaatgaatta gtacaagaat tgagtgatag gttggataaa gaattgcaaa
     3481 aaagaggtct tattcatcat cgtgttggtc atggatggac aggtgaagtt ttaggttact
     3541 cttcaaaatt tggctgggaa tcaggtctta gtatttcaga ggagaagaaa ccctatgtcg
     3601 ctgaaataaa cgggaaacga gaattgttta atacggctcc gattttaacc agcctggatt
     3661 tttcaaatcc agatgtagct gataagatgg tagaaattat caaggattat gccaagaaaa
     3721 gacctgatgt taactactta catgtatggt tgtcggatgc tcgtaataat atttgtgaat
     3781 gcgaaaactg tagacaagaa ttggtttcgg atcagtatat tcgtattctc aatcaattgg
     3841 atagggcttt aacgagtgag ggattagata caaagatttg ttttctgctt taccatgagt
     3901 tgctatgggc gcctcagaaa gaaaaattag ataatcctga acgctttacc atgatgtttg
     3961 caccgattac aagaacattt gaaatgagtt atgcagatgt agattttgac aattccatac
     4021 ctacgcctaa accttatctg cgtaataaaa ttatacttcc gaattctctt gaggaaaatt
     4081 tatcttatct ttttgagtgg caaaaaacat ttaaaggaga tagtttcgta tatgactatc
     4141 ctttagggcg tgctcattat ggcgatttag gctatatgaa aattagtcaa accatttaca
     4201 gagatgtatc ttatctttct aacctacatt tgaacggtta catttcgtgt caagaattac
     4261 gtgccggatt ccctcataat tttcctaatt atgttatggg ggaaatgctc tggaagaaga
     4321 caagaagtta tgaagaattg attgaagaat acttttctgc tttgtatggg tcaaattggc
     4381 agtctgttgt tgaatattta gaaaaattat ccagttattc ctcatgtgat tattttaatg
     4441 caattggcag tcgtcaaaat gatgttttag cgaatcatta ttatatagct tacaatctag
     4501 ctgataattt tttgccaatt attgaggaaa atatttctaa gttattaaat agtcaaaagg
     4561 atgaatggaa acagctcagt tatcatcgtg aatatgttgt taagatggcg aaggctttat
     4621 atcttcaagc aaccggaaaa acaaggcaag ctcaagatga atggagaaat gtgttgaatt
     4681 atatccgtgg gcacgaactg ctattccaat ctaatttgga tgtttatcgt gtaattgaag
     4741 tagcaaaaaa ttacgctggt ttccacttat aaatcataag tatagaaaat gaaccaaggt
     4801 attcagagaa gattgatcct aaatattatg aaatttaagg atttttaaga tatttagggt
     4861 cgactttcta tttatatcgt agcgaagtca ttttaataat gatgtgtaaa agatggatca
     4921 agattgagga ggaagaaaga tgaaatcaaa agaagaaata aatatgcttg gttttacaat
     4981 tgtcgcttac gcaggagatg caaggtcaga tttgatggat gctttggcgt ttgcgagaga
     5041 tggatatttt gaacaggcaa gagaattggt tgagtctgca aacgactcaa tagtgtctgc
     5101 ccatcgagaa cagactaatt tattagcgga ggaggcatct ggagataatt ttgaagtgag
     5161 ttttatcatg attcatggtc aagatacctt gatgacaacg atgctattgt atgatcaggt
     5221 caagtttttt attgatgaat atgaacgaat tcgaaagatt gaagaacata ttggtttgca
     5281 atgaggatta gtcatggaaa atttacaggt taaagcctta ccgaaggagt ttttattagg
     5341 agctgctacc gctgcttatc aagtagaggg tgcaactagg gtagatggca aaggaacaaa
     5401 tatgtgggat gtttatttgc aagaaaacag tccgttctta ccagatccgg ctagtgattt
     5461 ttattatcgt tacgaagagg atatagcttt ggcggcagaa catggtttgc aggctttgcg
     5521 tttatctatt tcttgggttc gtatatttcc tgatatagat ggggagccta atatattagc
     5581 tgttcgttat taccatagag tctttcagtc ttgcttaaaa cataatgtga ttccgtttgt
     5641 ttctttacat cattttgatt cgcctcagaa aatgttagaa acaggggatt ggttgaatag
     5701 agagaatatt gatcgtttca tacgatatgc tcgcttttgt ttccaagaat ttacagaagt
     5761 caagcattgg tttacaatca atgaactgat gtctcttgct gcaggtcaat atataggagg
     5821 tcagtttcct ccaaatcatc attttcaatt atctgaagca attcaagcga atcataatat
     5881 gttgttggcg catgctcttg cagtcctcga atttcatcaa ttagggattg agggaaaggt
     5941 aggttgtatt catgctttaa agccaggcta tcctattgat gggcaaaaag aaaatatttt
     6001 ggcagctaaa cggtatgatg tttataataa taaatttcta ttagatggaa cttttttggg
     6061 ctactacagt gaggacacgc tttttcactt gaatcaaata ttggaagcta ataattctag
     6121 ctttattatt gaagatggtg atttagaaat tatgaagaga gctgcagctc ttaatacgat
     6181 gtttgggatg aattattatc gttcagaatt tattcgtgaa tacaaaggtg aaaatagaca
     6241 agaatttaat tcaacaggaa taaaaggaca gtcttctttt aaattaaatg ctctaggtga
     6301 atttgtaaaa aaacctggta ttccgacaac agattgggat tggaatattt atcctcaagg
     6361 gttatttgat atgttgcttc gtatcaaaga agaatatcct caacatccgg tcatttattt
     6421 aactgaaaat ggtacagccc ttaaagaagt taagccagag ggcgagaatg atattattga
     6481 tgacagtaag agaatccgtt atattgagca acatttacac aaagttttag aggctcgaga
     6541 tagaggagtc aatattcaag gctattttat atggtctttg caagatcaat tttcttgggc
     6601 gaatggctac aataagcgat atggtctttt ctttgttgat tatgaaacac agaagagata
     6661 tattaagaaa agtgctcttt gggtaaaagg gctaaaacgg aattaaggtt agcgatttga
     6721 ctgatgttta atatatttta actatgagct taaatttttt acaggaggag tttttatgga
     6781 taagttagtc gctgccattg aaaagcaaca agggaaattt gaaaaaattt ctactaataa
     6841 ttatatgatg gctattaaag atggatttat tgctactatg cctttaatta tgttttcaag
     6901 ctttttgatg attattatta tgattcctaa aaatttcgga gtagagttac cgagtccagc
     6961 tattgcctgg atgaggaaag tgtatatgct aaccatggga gttttgggta ttattgtttc
     7021 agggacagtt gcaaagtcat tggctggaaa tgttaataga aaaatgcctc ctggaaaggt
     7081 aataaatgat acttctgcaa tgttggcggc catatgtggc tatcttgtat taactgtaac
     7141 gcttgtagtt gatgagaaaa cgggatctac aagtttgtcg acaaactatt taggatctca
     7201 aggattgata acttcgtttg tcagtgcctt tattactgta aatgtttacc gattctgtat
     7261 taagcgagac attactattc atttacctaa ggaagttcct ggggctatat cacaagcttt
     7321 tagagatatt tttccttttt cttttgtttt acttattagt ggtttgttag atattgtatc
     7381 tcgttttagt ttagatgttc cttttgccca agtatttcaa caactattga ctcctatttt
     7441 taagggggca gaatcatatc ctgctatgat gttgatttgg tttatgtgtg ctttgctttg
     7501 gtttgttgga attcatggac catctattgt cttacctgct gttacagctt tacaactgag
     7561 caatatggaa gagaatgctc aacttcttgc aaatgggcag ttcccttatc attctttaac
     7621 acctaatttc gggaattata tcgctgctat tggaggaacg ggggctacct ttgttgtacc
     7681 atttattttg attttcttta tgcggtctaa acaattaaaa tcggtaggta aagctacaat
     7741 tactcctgtt ttatttgcgg taaatgaacc tcttctattt ggtatgcctg ttattttgaa
     7801 tccctatctt tttgtccctt ttttgatgac tccaccagtg aatgtatttc taggaaaggt
     7861 atttattgat ttctttggaa tgaatggatt ttatatccag ttaccttggg cctttcctgg
     7921 tcccttggga ttgttaattg gaacgaattt tcaacttatc tcctttgtat ttttatcttt
     7981 gatgttagtt gtcgacatat tgatttattt gccattctgt agagcgtatg atagacagtt
     8041 actggtgaaa gaagatattg caagctcaaa tgatattatt ttagaggagg atacaagtga
     8101 aataatgcct ggtgagatag atgtaataaa aagtaaggag ttgaaagtac tggttctttg
     8161 tgcagggtct ggaacaagtg cgcaattagc caatgcaatt aacgagggcg ctcaattagc
     8221 agaagttaga gtgattgcga attcaggagc gtacggagct cattatgata ttatgggtgt
     8281 ttatgattta attattctgg ccccacaagt tcggagttat tatagagaga tgaaggtgga
     8341 tgcagaaaga ttaggtattc agatagttgc taccagagga atggaatata ttcatttaac
     8401 aaagagtcca agtaaagcct tacaatttgt attggagcat taccaagctg tgtagtaagt
     8461 ttttccatct tttatttgag taaagatttt gcttacagat aggcttggat ttaaaaacgt
     8521 tccccctttt ttaatataag aatccctctt tcacaattgt aaaaagaggg attttgtatt
     8581 ttatctctta gaccaagttc tcttcataaa gagaaggagg attgggtaaa tctccaagcg
     8641 ccctgcaatc attgcaaagg ataggagaat ttttgagatg ggactaaaga ttgagaaact
     8701 agaagtggtt cctagaatag gcccgatatt attgaaacag ctaaagacag cgctggtcac
     8761 gaccagaaaa tcattgctat ctaggctgac aataaagata agcgctagca aaatcatagc
     8821 atagatgaca aagtacttga gaatcttatg ctgggtatct ttgtcaatca ccgtttgatt
     8881 aacatggagg gtcaaaacac ggtggggcga taggattgac aaaatttggt ttttggcaat
     8941 ttttgaaagg atgaggcctc gaataatctt gagtccacct gcagttgatc cagcagagcc
     9001 accgattgcc atgaggaaaa ggaggataaa ctgggagaag aggggccagt tggtaatatc
     9061 tccatatcca aaaccagttg ttgtaatgat gttggaaacc tggaagaagg tcatttcaaa
     9121 gctctttgaa aaccctgggt agaggtagag ggtgttgagg ctaatcaagc ctgtagaaac
     9181 cagtacaatg accaagtaag cccgaagttc ttcgtcacca aagaaggcct tgatgcgacg
     9241 gagcatgagg tagtagtaga ggttgaaatt taccccaaaa accagaactc cgatactgac
     9301 cagataggta atcagtgagc tgccatagtg ggcaattccg tcgttataga cggtaaagcc
     9361 tccagttccc gctgtcccca tagcaatgac aaaactatcg tagagaggca taccagctag
     9421 ataatagatg atgacaaaga gggagaagag agctagataa aggagataga gaatctgggc
     9481 agtgtttttt agtttggata caaccttgcc aaaaacagga cctggaacct cagccttcat
     9541 cacctctagg tggctatttt tggcattgtc cataatagca agtgcaaaaa caagcactcc
     9601 catccctcca atcaagtggg taaaacttcg ccagaagagg agggaacggc tgagaaccga
     9661 aatgtcgttc aaaatacttg ctccagtagt tgtaaaccca gaactaattt caaaaaaggc
     9721 atcaataacg ctagggattt gcccagaaaa gacaaagggg agaccaccaa agaaagacca
     9781 aaggatccaa cagagggcaa cgatcaagac tccctccttg gcataaatcc gttgattttt
     9841 tggcttctgt aaactccctg aaccgcctaa caatacgaga atccctatgg tcgaaaagag
     9901 ggctgtaaag acttggctcg attcacggta atagacagcg atagccacag gaaccaagag
     9961 gagaacagct tcaatcaaaa gtaactttga aaggaggtaa cgaatcatac ttttattcat
    10021 ttcttacctc gcaatcaagt cataaatctt ggtgatgttt ggcaacaagg ttgttactag
    10081 gagcttgtct ccaacttcca acatatcctc cccagttggg aaaatagtct tgccctttcg
    10141 aataatggct gcaataagaa cccctttttt caatttcagt tgagaaagag gtttggcagt
    10201 cattttattg gcttccttga tatggaattg cagggtttca atttggccat tggctagatg
    10261 gtgcatggct tgaaggtctg aatactgggc attaactcga ccacgaataa agtgcataat
    10321 cgtatctaca gcgatgcttt taggtgtgat gatacttgaa aaatcaggcg cattgataat
    10381 ctcgaggaga ctggtacgat tgaccttagt aatatttttc tgtacaccta ccctgtcaag
    10441 gaacatagat gtaatcagat tttcctcatc gacacctgtt agagtcgcaa cggcatcata
    10501 gtgttgagca ctttcttcca gcaggatatc ttttgcggtt ccatctcctt gaacgatgta
    10561 gagatttggg aatttctcgc taaagaagct ggcgatttca ggattgattt caatgacttt
    10621 tgtatcgata cgactatctt tgagaatacc aagtagataa taggcaattc tacctgcccc
    10681 aacgatgaga aggctcttca cggcgcgtga tttaaaataa ttatggaaga gtatcatatc
    10741 gacacggtta ccagtgacaa agattctatc tttatcctgt acagtcatgt caccgcttgg
    10801 aatgataatt tgatgatccc tctctatcgc acagacaatg acattaccaa attttttacg
    10861 aaaatcagaa atgggcattt ggcaaagacc gctggtggac ttgacgacaa attccatgag
    10921 gctaacgcgt ccaccagcaa agcgttcgac agacagggcg ttggggaagt caatgatatt
    10981 cgcgatagcg cgggcagcca agagctcagg attaacgata agagaaaaac cgagaatatt
    11041 cttttccttg aaataagagt tagaatattc agggttccgc acccgaacga tagtttcttt
    11101 agctcccatt ttcttggcta gaactgctgc aatcatgttg acttcatcgt gctcagtcag
    11161 ggcgataaag atatcacaat cttggacgct ggcttgctca agaatggcaa aatcggcccc
    11221 gttaccaagg ataccaatga tatcaaagcg actgacaata tgattgagaa cagcttcgtc
    11281 gtgctcaatc agcaaaacat catgcttttc tgcaaccaag gagcgacaga gggcaaaacc
    11341 aacttttccc cctccgacaa ggataatttt cataataaaa cctacttttt catgatgtaa
    11401 ctatcatacc ctttttcaag aaaaaatgca cctactagct aataacaaga gcttttagtg
    11461 aaaattcgct ataaggtaaa actataccct aaccaattga aatagctatt agcgactttc
    11521 tctgaaatat ggtatgataa aggatataca aggagataaa atgaataata atttactggt
    11581 attacaatca gactttggtc tggttgatgg tgcggtatcg gctatgattg gagtggcttt
    11641 agaagagtct ccaaccttaa aaatccatca cttgacgcac gatatcacgc cttataatat
    11701 ttttgagggg agctatcgtc tctttcagac ggtggattac tggcctgagg gaacgacgtt
    11761 tgtatcggtt gtcgatccag gtgtcggttc gaaacgtaag agtgtagttg ccaagactgc
    11821 aaaaaatcaa tacattgtca cgccagataa tgggacgctt tcctttatca agaaacacgt
    11881 tggcattgta gccattcgtg agatttctga ggtggccaat aggcgtcaaa acacagagca
    11941 ttcttatacc ttccacggtc gtgatgtcta tgcctatact ggtgctaaac tggccagtgg
    12001 tcacattact tttgaggaag tagggccaga gctcagtgtg gaacagattg tagagcttcc
    12061 agtcgtagcg accatcatag aagatcatct ggtgaaggga gccattgata ttctggatgt
    12121 gcgtttcggt tcgctttgga cctctatcac acgggaagaa ttttacaagc tggaaccaga
    12181 atttggtgat cgttttgaag tgaccatcta tcatgctgat atgctggtct atcaaaatca
    12241 ggttgtctat ggcaaatcat ttgcagatgt gagaattggg caacccatcc tttacatcaa
    12301 ctctctctat cgtttaggtt tggctatcaa ccaaggttcc tttgccaagg cctataatgt
    12361 aggtgtcggt tcatcttgga ccattgaaat aaagaaaata gaaggataaa ataggagaat
    12421 agtatggaaa tcaaatttac aattaaacaa gttgttgctg tcggaattgg cgctgccctc
    12481 tttgtcgtca tcgggatgat caacattcca acccctgttc caaatacaag catccagctt
    12541 cagtatgcgg tacaagcgct actttctatt atttttggac cgattatcgg tttgcttgtc
    12601 gggttgattg gtcatgcaat caaggactct cttgctggtt atggtctatg gtggacttgg
    12661 attatcgcta gcggactctt tggtctagtt gtgggacttt ttagaaagta cgttcgagtg
    12721 atcaatggtg tttttgactg gaaagatatt cttattttta acctcattca actacttgca
    12781 aatgcccttg tttggggtgt cttggcacca cttggagatg ttgtgattta tcaagaagcg
    12841 gcagaaaaag tatttgcaca agggattgtt gcgggaattg ccaatggtgt atctgtagct
    12901 attgcaggaa ctcttctctt acttgcctat gcaggaaccc aaactcgtgc aggaagtttg
    12961 aaaaaggact aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
    13021 tcaaaacagt gttttgagat tgtggataga actgacgaag tcagctcaaa acatggtttt
    13081 gaggttgtag atgaaactga cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa
    13141 actgacgaag tcagtaacca tacctacggc aaggcgaagc tgacgtggtt tgaagagatt
    13201 ttcgaagagt ataaaatgat ggggaaggct gggcaactag tctttttcga tgtttataga
    13261 ttagttaggc aagtaagcta ggataggaat ctttttggcg ctaagatttt aagagaagag
    13321 actgcaagaa gggcttgatt tatgataaaa tagaagtcta agaagcgaat gaagagagta
    13381 agatgaaaga agctataatt gagtggaagg atttctcttt ccggtatgaa acacaacaag
    13441 aaccgacctt gcaagggata gacttgacca tttacaaggg agagaaagtc ttaattgttg
    13501 gaccatctgg gtcaggtaaa tctaccttgg gtcagtgttt gaatgggatt attcccaata
    13561 tttacaaggg tcagacatat ggagaatttt tgataaaggg tcaagtagcc tttgatatga
    13621 gcatctatga taagtctcat ctggttagca cagttttgca ggatacagat gggcagttta
    13681 ttggcttgtc tgtggcagaa gatttggcgt ttgctctgga aaatgatgtg acagccctag
    13741 atgagatgaa aggtcgtgtt tataaatggg ctgaaaagct ggaccttctt cctttactgg
    13801 atcagcgtcc tcaggatttg tcaggtggac aaaagcagcg agtcagtctg gctggtgtct
    13861 tgattgatga aagtccgatt ctcttgtttg atgagccact cgccaatcta gatcccaagt
    13921 caggtcagga tattatcgaa ttgattgacc agattcataa ggaagagggg acgacgactc
    13981 tgattatcga gcaccgtttg gaggatgttc tgcatcgccc tgtggatcgg attgtcttga
    14041 taagcgatgg tcgtatcctt tttaatggga gccctgacca gttgcttgcg actgatttat
    14101 tgactcaaaa tggaattcga gaaccccttt atctaacgac tctccgtcaa ttaggtgtgg
    14161 acttagtcaa ggaagaacag ttagcgaatc tggataacat gtctatctca aaaggtcagg
    14221 ttcagctgca gaatgaactg gcaaaagaaa ctccagaatt gcagtcactc tttaaattag
    14281 aggacgtgtc tttctcttat gatgatagac cgattttaaa atccctacat ttagatatta
    14341 aaaagggtga aaagattgct attgtcggaa aaaatggagc agggaaatca actctagcca
    14401 aggctataag tagctttatt cagacggaag gacgctatct ttgggaaaaa caggatataa
    14461 aaggcgattc tgttgcagag cgggcggaac gagtaggcta tgtgctacaa aatcctaatc
    14521 aaatgatttc aaccaatatg atttttgatg aggtggctct agggctccgt ttgcgaggtg
    14581 tggatgagaa ggaaattgaa acgagagtct atgaaacctt gaaaatctgt ggactttatg
    14641 aattccgtaa ttggcctatt tctgccctgt catttggtca gaaaaaacgt gtcaccattg
    14701 cttcaatttt ggtcttagga gctgaaatta ttctcctaga tgaaccgact gcaggtcaag
    14761 atcagaagaa ctatactgag attatggaat ttctcgaaga gttacatcaa aaagggcata
    14821 ccattgtcat gattacccat gatatgcaat tgatgctgga ttattcagac cgggtccttg
    14881 tcatggtgga tggagaattg attgccgata ctgttccagc cagtctgttg agcgatcctg
    14941 agctgttagt aaaagccaat ctaaaagaaa cctccatctt taacttggct aagaaactag
    15001 atgtggatcc actggattta acggcatttt acaaagaaag gagagaggga tgcaagctaa
    15061 attaatcggt taccagcata gagatactgt gattcatcgc ttgtcaggag ctgggaaact
    15121 tctctttttc attctggtat cattggcggc catgattagc tatgatacca gaatgctctt
    15181 gctgattgcc atcttttcag tctttctcct ctatttatca gaaattcgct ttaaagatat
    15241 ttcctttgta gccgtttttg cgacggtatt tgccgtttta aacgttttga tggtctatct
    15301 cttttctccc gagtatgggg ttggacttta tggagagaga agtgtgattt ggcagggaat
    15361 cggtgtctac actctaacca gccaggagct cttttatctg ctaaatttgg ccattaagta
    15421 tctttgcacc attcctctgg ctattatctt tttgatgaca acccatccta gtcagtttgc
    15481 ttccagttta aatcaaattg gtgtgcccta taagattgct tattctgtca gcctgacctt
    15541 gcgctatatt ccagatttgc aggaagaatt ctttactatc aagatgtctc aggaggcgcg
    15601 tgggatggaa ttatccaaga aagcttctct tatgcaacga atcaaaggca atctgctcat
    15661 tattacgccc ttgattttta gctcgctaga acgcattgat accattgcga ctgccatgga
    15721 gcttcgccgc tttgggaaag agaaaaaacg cacatggtat agttatcagg ccttgaaaaa
    15781 aggagactat attaccttgc tcttggcaac cttgttttta gtagttagtt tactacttat
    15841 cttgcagaat cagggacgat tttacaaccc ttggaaatag cttgaaaaaa ttgaaaaaat
    15901 caagtcattt ctattgacaa tgattctgaa agtgttatac taagaaagta gtttcgctga
    15961 tttacttcaa acctgttgtg aggtaagtta acgatgcctt aaccacgctg tttgctgagc
    16021 ttgactccgg gcagtgtggc tatttttttg caatggtgaa aggaagcaag tcatgacaaa
    16081 tcacattgta ttatttgaac ctcaaattcc acaaaataca ggcaatatcg cgcgtacttg
    16141 cgctgcgacc aattctcccc tccacatcat caagcctatg ggctttccta ttgatgaccg
    16201 caagatgaag cgggctggat tggattactg ggataagcta gagatttatt tttacgagag
    16261 tttagaagat ttcatatctc agatgaaggg aaaactctat ctgatttcga aattcgcgga
    16321 aaaaatctat tctgaggtgg atttatcgac tgacgaggac cattattttc tctttggacg
    16381 tgaagacaag ggcttacctg aagattttat gcgagaacat cctgagaagg ctctccgtat
    16441 tcccatgaat gatgaacatg tccgcagtct caatgtgtct aataccgtct gcatgattgt
    16501 ctatgaggct cttcgccagc agaactttgc aggtcttgag ctcgtccata cctatgaagt
    16561 ggataaattg aaataaaaaa tgaaaatgaa caaaatgctt gcgcttgcaa gcgttttttg
    16621 ttatgataaa agagtcttca gggcagggtg tgattcccga ccggcggtga ctttaactag
    16681 gaaatgatct tttcctttta tactttgttg acaagctttg cctaaccaga agttatgcct
    16741 acagcttgtc gcctagtcta aaagaaaaat ctctatttct ttccctttaa agaagtccgc
    16801 gagcgcaagc tgatgtggtg agattccaca accgacagta tagtctggat gggagaagac
    16861 gaaagaatag ctttgtctgt tttgatagat ttatagccgg attgtaacca cttgctttgt
    16921 ttttctttaa tagagtaaga gggaactttt gggatataaa aagtgagaat agatagagga
    16981 atcctttcca acttcttctg attttataga aaattggagg aacctgttat gacaaacaca
    17041 cgtcgacttt cgaccattgc aattctatca gccatctcat ttgtgctgat gtactttgat
    17101 tttccgcttt taccagcggc atctttcctc aagatcgaat ttagtatctt gccagtcctt
    17161 gtgggtctgg tggtcatgga tttgcctgct gctctaggag tgctcttgct tcgctcactc
    17221 ttgaagttgc ttcttaacag ccaaggagtg aatacttaca ttggtttgcc gatgaatatc
    17281 gtagctttgg gagtttttgt catcgtattt gctttgattt ggaaaaagga acggacaacc
    17341 cttcgtttcc tactaggctc tctagctgga actattggtt taaccttggc catgttggtt
    17401 ctcaactatg tttatgctgt tcctttgtac gctaagtttg ctaactttga tattggaaaa
    17461 attttgggac tttccaacta cctaatgacc atggtattac cttttaactt gattgaaggt
    17521 gttatctttt ccgtttcatt ctggttgttg tatgttctct tgaaaccaac cttaaaacat
    17581 tatgagagat aaacaaacat ttttaatgaa gggcagtttt gcccttttac ttttcgttat
    17641 tcttggctac atggtcaaat tttaccctga aacgctggtc aattttgacc aatcgattca
    17701 gactgccatt cgaggagact taccagatta tttgactatt ctttttcgag ccctcacacg
    17761 tctgattgat atcccagtga ttatcacttg ggttgtcatt acagcttttg tcttttatcg
    17821 taagcgatgg aagatagaaa gtttcttcat gctgggaaat ctggctttgg caggtctttt
    17881 aatcgtgacc tttaaaaata tctaccagcg cccacggcca gatatcttac atctggtgga
    17941 ggagaaggga ttttccttcc caagtgggca ttctctggct gtaaccttga tggtaggtac
    18001 tttgattgtt attcttagtc agcggattaa agatccagtc tggagaaaaa tcgtacaaat
    18061 cgtccttggc ctctacctag tcagtgtgct ggtatcaaga gtctatctgg gagttcatta
    18121 cccatcagac gtccttgcca gtctctgtgt gggcttggga gtcctgttta tcgagtttcc
    18181 cttctatgac aagctccgct tccaatggcg atttaaaggc aaacagaagt gagtatcgaa
    18241 ttcccttgag gagaaagaaa tgaaagtcaa catagcagat cttcatccga ctcaactata
    18301 tttatcagaa aagaagttgc aagatattca gatgctttac cagtcggcag aaacaatcca
    18361 agtcgatcca atcagtattc ttgcctttgg agattgtttg ctgattacag atgggcatca
    18421 cagggcttat cagactttat tggcagatcg ggatacgatt tctgctgagt gggatagaga
    18481 tggtggtgat gaactatatc atctctatgc gcaagcttgc gaggaaagaa agatttactc
    18541 tgtttttgat ttagaagatc gtatcctagc tcaagatggg tatgaagcaa aatggtataa
    18601 ctggtgtgat ggttttaatc aagcagcaac tcttttgttg aaaaggtagt gcattgtgtt
    18661 ttgttcctta ttataaggtc aatcattgtg aggaagcttt tgcttggtat caggatgtga
    18721 acttggttta cctcgtagat ggggtgaagc ttccttacag tcaagcgacc ttggaagcca
    18781 tgtattccta tttggatcgg catggtgagc ttttttggat tgaagtcaag gagaagggag
    18841 aatggtttcc aattggggat attacactat ctcaggataa tctccccatt gtgattggga
    18901 attccgctta ccaacatcga ggacttggaa aaaagattct aagtgctttg attgaattgg
    18961 ctcgagtaaa aggatggaaa gaattgagag tcaaggaaat ctacacctac aatcatgctt
    19021 ctaggaggtg tttcaagtcg cttggatttg tggaaaatgg agcaacagaa aaaggaagga
    19081 gttttatatt ggaattagtc taatcctgcc attttctccc ccttaacctt tgactattct
    19141 gcaaaattat cgtaaaataa agagtaaatg ataaaatgag gtcagagtct gttcgctctg
    19201 gcgatagtag tataaatgag gagaaacgct ttggaattag aagtatttgc tgggcaagaa
    19261 aaaagtgaac tatctatgat tgaggtagcg cgtgctatct tggaacttcg tggtcgcgat
    19321 catgagatgc attttagcga tcttgtaaac gaaattcaaa actaccttgg aacatcaaac
    19381 agcgatatcc gcgaagcttt gcctttgttc tacacagagt tgaactttga cggtagcttc
    19441 atctcacttg gggacaacaa atggggtctt cgttcatggt atggtgtgga cgaaatcgac
    19501 gaagaaatca tcgctcttga agaaaatgac gacgatgaag tagcaccaaa agctaagaaa
    19561 aaacgtgtca atgcctttat ggatggtgat tcagatgcca ttgactacaa tgcagatgat
    19621 ccagaagacg aagatgcata cgaagcagat ccagctcttt catacgatga tgaaaatcca
    19681 gatgatgaaa aaaatgaagt ggaagcttat gatgcagaaa tcaacgaaat cgctccagat
    19741 gacttgggag aagatgtgga tctcaacgaa gacgacgacg agttttcaga tgacgacgct
    19801 gaaaccagcg aggaataaga gttagctatt gacaattatc ctatttttag gtatcatatt
    19861 gtttgggcac ctcttttaga ggtcggggct ccctagttct tagggagcta tttttgtttt
    19921 ttcaagaagt tatcttcttg tattttatac tcaatgaaaa tcaaagagca agctaggaaa
    19981 ctagccgtag gctgctcaaa acactatttt gaggttgtag ataagactga caaagtcagg
    20041 aacacatatc tacggcaagg cgacgttgac gcggtttgaa gagattttcg aagagtatta
    20101 gctgtgaatc tggtgcagtc gtcccagatt attcttatta gtagggtctt gttttctata
    20161 tcccctcgta gttaacaaga ccttgagcat tttagaaaga ggaatctatg tctacgaaat
    20221 atatttttgt aactggtggt gtggtatcgt ctattgggaa agggattgtg gcagcgagtc
    20281 taggccgtct cttgaaaaat cgtggtctca aagtaaccat tcaaaagttt gacccttata
    20341 tcaatattga tccgggaacc atgagtcctt accagcacgg ggaagttttt gtgacagatg
    20401 acggagctga gacagatttg gacttgggtc actatgaacg tttcatcgat atcaatctca
    20461 acaaatattc caacgtgaca actgggaaaa tttacagtga agttcttcgt aaagaacgcc
    20521 gtggagaata ccttggggca actgttcaag tcattcctca tatcacagat gctttgaaag
    20581 aaaaaatcaa gcgtgccgct ctaacgaccg actctgatgt cattatcaca gaggttggtg
    20641 gaacagtagg agatatcgag tccttgccat tcctagaggc tcttcgtcag atgaaggcag
    20701 atgtgggtgc ggataatgtc atgtatatcc atacaacctt gcttccttac ctcaaggctg
    20761 ctggtgaaat gaaaaccaaa ccaacccaac actctgtcaa agaattgcgt ggcttgggaa
    20821 tccaaccaaa tatgttggtt attcgtacag aagagccagc tggtcaagga attaaaaata
    20881 aactggccca gttctgtgat gtggcaccag aagccgttat cgaatcgttg gatgttgaac
    20941 acctttacca aattccactg aacttgcagg cacaagggat ggaccaaatt gtttgtgatc
    21001 atttgaaatt agacgcacca gcagcggata tgacagaatg gtcagccatg gtggacaagg
    21061 tcatgaacct caagaaacaa gttaagattt cccttgttgg taagtatgtg gagttgcaag
    21121 atgcctatat ctcagtggtc gaagccttga aacactctgg ctatgtcaat gatgtagaag
    21181 ttaaaatcaa ttgggtcaat gccaatgatg tgacagcaga gaatgtagca gaactcttgt
    21241 ctgatgcgga cgggatcatc gtaccaggtg gttttggtca acgtggtaca gaagggaaaa
    21301 tccaagccat ccgctatgcg cgtgaaaatg atgttccaat gttgggagtc tgcttgggaa
    21361 tgcagttgac atgtatcgag tttgctcgtc acgttttagg tcttgaaggt gccaattctg
    21421 cagagcttgc accagaaaca aaatacccta tcattgatat catgcgtgat cagattgata
    21481 ttgaggatat gggtggaacc cttcgtttgg gactttatcc gtctaagttg aaacgtggct
    21541 ctaaggctgc tgctgcttat cacaatcaag aagtggtgca acgccgtcac cgtcaccgtt
    21601 atgagtttaa taatgccttc cgtgagcagt ttgaggcagc aggttttgtc ttttcaggag
    21661 tttctccaga caatcgtttg gtagaaatcg tggaaattcc tgaaaataaa ttctttgtag
    21721 cttgtcagta tcaccctgaa ctgtcaagcc gtccaaaccg accagaagaa ctctacactg
    21781 cctttgttac tgcagcggtt gagaacagca attagcaaaa tcagaacctt tgagaaaaat
    21841 ctcagaggtt ttttgcatac gatgatattg cagtatatct gaggtagggg tcctctgtat
    21901 gtacctgcta ccgttgaaat caatagcgac tccctcttgc cctgtgctag tgaatggatt
    21961 tatcagtata ttgaaatgaa ataaaatttg aacaaattaa ttcggaaagc caaatcaatt
    22021 tctagcaaag ttttaggaac tggattgtat agtgaattga aataagatgt gaacatctct
    22081 atcagaaaag tcaaattaat ttatagaaat attttagcag tgcagaagga gtagcgacag
    22141 catctgaaac tgcagaagca gctagcgcag ctaaaccaga ggaaaaagca agtgaggtgg
    22201 ttgcagaaac accatctgca gaagcaaaac ctaagtctga caaggaaaca gaagcaaagc
    22261 ccgaagcaac taaccaaggg gatgagtcta agccagcagc cgaagctaat aagactgaaa
    22321 aagaagtcca gccagatgtc cctaaaaata cagaaaaaac attaaaacca aaggaaatca
    22381 aatttaattc ttgggaagaa ttgttaaaat gggaaccagg tgctcgtgaa gatgatgcta
    22441 ttaaccgcgg atctgttgtc ctcgcttcac gtcggacagg tcatttagtc aatgaaaaag
    22501 ctagcaagga agcaaaagtt caagccttat caaacaccaa ttctaaagca aaagaccatg
    22561 cttctgttgg tggagaagag ttcaaggcct atgcttttga ctattggcaa tatctagatt
    22621 caatggtctt ctgggaaggt ctcgtaccaa ctcctgacgt tattgatgca ggtcaccgta
    22681 acggggttcc tgtatacggt acactcttct tcaactggtc taatagtatt gcagatcaag
    22741 aaagatttgc tgaagctttg aagcaagacg cagatggtag cttcccaatt acccgtaaat
    22801 tggtagacat ggccaagtat tatggctatg atggctattt catcaaccaa gaaacaactg
    22861 gagatttggt taaacctctt ggagaaaaga tgcgccagtt tatgctctat agcaaggaat
    22921 atgctgctaa ggtaaaccat ccaatcaagt attcttggta cgatgccatg acctataact
    22981 atggacgtta ccatcaagat ggtttgggag aatacaacta ccaattcatg caaccagaag
    23041 gagataaggt tccggcagat aacttctttg ctaactttaa ctgggataag gctaaaaatg
    23101 attacactat tgcaactgcc aactggattg gtcgtaatcc ttatgatgta tttgcaggtt
    23161 tggaattgca acagggtggt tcctacaaga caaaggttaa gtggaatgac attttagacg
    23221 aaaatgggaa attgcgcctt tctcttggtt tatttgcccc agataccatt acaagtttag
    23281 gaaaaactgg tgaagattat cataaaaatg aagatatctt ctttacaggt tatcaaggag
    23341 accccactgg ccaaaaacca ggtgacaaag attggtatgg tattgctaac ctagttgcgg
    23401 accgtacgcc agcggtaggt aatactttta ctacttcttt taatacaggt catggtaaaa
    23461 aatggttcgt agatggtaag gtttctaagg attctgagtg gaattatcgt tcagtatcag
    23521 gtgttcttcc aacatggcgc tggtggcaga cttcaacagg ggaaaaactt cgtgcagaat
    23581 atgattttac agatgcctat aatggcggaa attcccttaa attctctggt gatgtagccg
    23641 gtaagacaga tcaggatgtg agactttatt ctactaagtt agaagtaact gagaagacca
    23701 aacttcgtgt tgcccacaag ggaggaaaag gttctaaagt ttatatggca ttctctacaa
    23761 cttcagacta caaattcgat gatgcagatg catggaaaga gctaaccctt tctgacaact
    23821 ggacaaatga agaatttgat ctcagctcac tagcaggtaa aaccatctat gcagtcaaac
    23881 tatttttcga gcatgaaggt gctgtaaaag attatcagtt caacctagga caattaacta
    23941 tctcggacaa tcaccaagag ccacaatcgc cgacaagctt ttctgtagtg aaacaatctc
    24001 ttaaaaatgc ccaagaagcg gaagcagttg tgcaatttaa aggcaacaag gatgcagatt
    24061 tctatgaagt ttatgaaaaa gatggagaca gctggaaatt actaactggc tcatcttcta
    24121 caactattta tctaccaaaa gttagccgct cagcaagtgc tcagggtaca actcaagaac
    24181 tgaaggttgt agcagtcggt aaaaatggag ttcgttcaga agctgcaacc acaacctttg
    24241 attggggtat gactgtaaaa gataccagcc taccaaaacc actagctgaa aatatcgttc
    24301 caggtgcaac agttattgat agtactttcc ctaagactga aggtggagaa ggtattgaag
    24361 gtatgttgaa cggtaccatt actagcttgt cagataaatg gtcttcagct cagttgagtg
    24421 gtagtgtgga tattcgtttg accaagccac gtaccgttgt tagatgggtc atggatcatg
    24481 caggggctgg tggtgagtct gttaacgatg gcttgatgaa caccaaagac tttgaccttt
    24541 attataaaaa tgcagatggt gagtggaagc tagctaagga agtccgtgcc aacaaagcac
    24601 acgtgacaga tatcactctt gataaaccaa tcactgctca agactggcgc ttgaatgttg
    24661 tcacttctga caatggaact ccatggaagg ctattcgtat ctataactgg aaaatgtatg
    24721 aaaagcttga tactgagagt gtcaatattc cgatggccaa ggctgcagcc cgttctctag
    24781 gcaataacaa ggtacaagtt ggctttgcag atgtacaggc tggagcaact attaccgttt
    24841 atgataatcc aaattctcaa actccgctcg caaccttgaa gagcgaagtt ggaggagacc
    24901 tagcaagtgc accattggat ttgacaaatc aatctggtct tctttattat cgtacccagt
    24961 tgccaggcaa ggaaattagt aatgtcctag cagtttccgt tccaaaagat gacagaagaa
    25021 tcaagtcagt cagcctagaa acaggaccta agaaaacaag ctacgccgaa ggggaggatt
    25081 tggaccttag aggtggtgtt cttcgagttc agtatgaagg aggaactgag gacgaactca
    25141 ttcgcctaac tcacgcaggt gtatcagtat caggttttga tacgcatcat aagggagaac
    25201 agaatcttac tctccaatat ttgggacaac cggtaaatgc taatttgtca gtgactgtca
    25261 ctggccaaga cgaagcaagt ccgaaaacta ttttgggaat tgaagtaagt caggaaccga
    25321 aaaaagatta cctagttggt gatagcttaa acttgtctga aggacgcttt gcagtggctt
    25381 atagcaatga caccatggaa gaacattcct ttactgatga gggagttgaa atttctggtt
    25441 acgatgctca aaagactggt cgtcaaacct tgacgcttcg ttaccaaggt catgaattca
    25501 attttgatgt tttggtatct ccaaaagcag cattgaacga tgagtacctc aaacaaaaat
    25561 tagcagaagt tgaagctgct aagaacaagg tggtctataa ctttgcttca ccagaagtaa
    25621 aagaagcttt cttgaaagca attgaagcgg ccgaacaagt gttgaaagac catgaaacta
    25681 gcacccaaga tcaagtcaat gaccgactta ataaattgac agaagctcat aaagctctga
    25741 atggtcaaga gaaatttaag gaagaaaaga cagaacttga tcgcttaaca ggtgaggttc
    25801 aagaactctt ggctgccaaa ccaaaccatc cttcaggttc tgccctagct ccgcttcttg
    25861 agaaaaacaa ggccttggtt gaaaaagtag atttgagtcc agaagagctt gcaacagcga
    25921 aacagagtct aaaagatctg gttgctttat tgaaagaaga caagccagca gtcttttctg
    25981 atagtaaaac aggtgttgaa gtacacttct caaataaaga gaagactgtc atcaagggtt
    26041 tgaaagtaga gcgtgttcaa gcaagtgctg aagagaagaa atactttgct ggagaagatg
    26101 ctcatgtctt tgaaatagaa ggtttggatg aaaaaggtca agatgttgat ctctcttacg
    26161 cttctattgt gaaaatccca attgaaaaag ataagaaagt taagaaagta tttttcttac
    26221 ctgaaggcaa agaggcagta gaattgactt ttgaacaaac ggatagtcat gttatcttta
    26281 cagcaccaca ctttactcat tatgcctttg tttatgaatc tgctgaaaaa ccacaacctg
    26341 ctaaaccagc accacaaaac aaagtccttc caaaacctac ttatcaaccg gcttctgatc
    26401 aacaaaaggc tcctaaattg gaagttcaag aggaaaaggt tgcctttcat cgtcaagagc
    26461 atgaaaatgc tgagatgcta gttggggaac aacgagtcat catacaggga cgagatggac
    26521 tgttaagaca tgtctttgaa gttgatgaaa acggtcagcg tcgtcttcgt tcaacagaag
    26581 tcatccaaga agcgattcca gaaattgttg aaattggaac aaaagtaaaa acagtaccag
    26641 cagtagtagc tacacaggaa aaaccagctc aaaatacagc agttaaatca gaagaagcaa
    26701 gcaaacaatt gccaaataca ggaacagctg atgctaatga agccctaata gcaggcttag
    26761 ccagcctcgg tcttgctagt ttagccttga ccttgagacg gaaaagagaa gataaagatt
    26821 aaatatcgaa aaatcttgtg aaatctttcc ttatatttcc aaagtgtgat ataatagttt
    26881 cgaataaaat aaataaagga gtttttgtaa catggcaaaa cttactgtta aagacgttga
    26941 cttgaaaggt aaaaaagtcc tcgttcgtgt tgacttcaac gtaccattga aagatggcgt
    27001 aatcactaac gataaccgta tcacagcagc tcttccaact attaagtaca tcatcgaaca
    27061 aggtggacgt gcaattcttt tctctcacct tggacgtgtg aaagaagaag ctgataaagc
    27121 tggtaaatca cttgctcctg tagcagctga cttggcagca aaacttggtc aagatgttgt
    27181 tttcccaggt gtcactcgtg gtgctgaatt ggaagcggca atcaacgctc ttgaagatgg
    27241 acaagttctc ttggttgaaa acactcgtta cgaagatgtt gacggcaaga aagaatctaa
    27301 aaacgatcct gaacttggta aatactgggc atcacttgga gatggtatct tcgtaaacga
    27361 tgcattcggt acagctcacc gtgcacacgc atctaacgtt ggtatctcag caaacgttga
    27421 aaaagcagtt gctggtttcc ttcttgaaaa cgaaattgcc tacatccaag aagcagttga
    27481 aactccagaa cgtccattcg tggctatcct tggtggttca aaagtttcag acaagatcgg
    27541 tgttatcgaa aacttgcttg aaaaagctga taaagtcctt atcggtggtg ggatgactta
    27601 cacattctac aaagcacaag gtatcgaaat cggtaactca cttgtagaag aagacaaatt
    27661 ggatgttgcg aaagctcttc ttgaaaaagc aaatggtaaa ttgatcttgc cagttgactc
    27721 aaaagaagct aacgcatttg ctggttacac tgaagtgcgt gacactgaag gtgaagcagt
    27781 ttctgaaggc ttccttggtc ttgacatcgg tccaaaatct atcgccaaat ttgacgaagc
    27841 tttgactggt gccaaaacag ttgtatggaa cggacctatg ggtgtatttg aaaacccaga
    27901 tttccaagct ggtacaatcg gtgtgatgga cgctatcgtg aaacaaccag gagttaaatc
    27961 aatcatcggt ggtggtgact cagctgccgc agcgattaac cttggccgtg cagacaagtt
    28021 ctcatggatt agtacgggtg gtggagcatc aatggaactt cttgaaggta aggttcttcc
    28081 aggacttgca gccctgacag aaaaataaga ttttataaac aaatcaaaga agagagggat
    28141 gaaagttcct cttttctttt gcttaaaata aaaacgcttc ctctcaacta ttactcataa
    28201 aaatcaccga tttatgataa aatggaaata gaaagttgag attatgagtt attttaaaaa
    28261 atataaattc gataaatccc agttcaaact tggtatgcga acctttaaaa caggtattgc
    28321 tgtttttcta gttctcttga tttttggctt ttttggctgg aaaggtcttc aaattggtgc
    28381 tttgacagcc gtttttagcc tgagggagag ttttgatgag agtgttcatt ttgggacttc
    28441 gcgtattcta ggaaatagta tcggtggact ctatgccttg gtctttttct tattaaatac
    28501 ctttttccac gaagcctttt gggtgacctt ggtagttgtt ccaatctgca ccatgttaac
    28561 cattatgaca aatgtagcca tgaataacaa agcaggggtt attggtggtg tagcagctat
    28621 gttaatcatt accctatcaa ttccaagtgg tgagacaatt ttgtacgtgt ttgtgcgtgt
    28681 attagaaacg tttatgggag tttttgtcgc aattatcgta aattacgata ttgatcgtat
    28741 tcgtctcttt ttagagaaaa aagaaaaata atgttacatt ttataacatt atcaattgac
    28801 gtttgtcttt ttttagacta taatagacag aaagaaggaa attgtaaatg aaggaaaaag
    28861 aatttcgccg aaatatggct gtttttccta tcggcagtgt tatgaagttg accgatttat
    28921 cggcgcgtca gattcgttat tatgaagatc aagagttgat caagcccgat cgaaacgaag
    28981 gaaatcgtcg catgtattcc ttgaatgaca tggatcgtct gcttgaaatc aaagattata
    29041 tctctgaagg ttataatatc gctgccatta agaaaaaata tgctgaacgt gaagcgaaat
    29101 ccaagaaagc ggttagtcag actgaagtac gtcgtgcact tcacaatgaa ctcctccaac
    29161 aggggcgttt tgcttcagta cagtcacctt ttggtcgcgg ttaggcaacc gcaagtagtc
    29221 atagattaag gagaaaactt atgccaatca cagctgcaga tattcgtcgt gaagtcaagg
    29281 aaaaaaatgt tacctttatt cgtcttatgt tctcagatat tttgggaacc atgaaaaacg
    29341 tcgaaattcc tgctacagat gaacagttag ataaggtctt gtcgaacaag gttatgtttg
    29401 atggatcttc tattgaaggt tttgtacgta tcaatgagtc ggatatgtac ttgtacccgg
    29461 acttggatac atggacagtc ttcccttggg gagatgaaaa tggaagtgtt gcaggtctga
    29521 tctgtgatgt ctatacaaca gaaggtgaac catttgcggg tgaccctcgt ggtaatttga
    29581 aacgagctct tcgtcacatg gaagaagttg gattcaaatc cttcaacctt ggtccagagc
    29641 cagaattctt cctatttaag ttggatgaaa atggggaccc aacacttgaa gtgaatgaca
    29701 agggtggcta ctttgacttg gcacctactg atcttgcgga caacacacgt cgtgagattg
    29761 tgaatgtctt gaccaaaatg ggatttgaag tagaagcgag tcaccacgag gttgcggttg
    29821 gacagcatga gattgacttt aagtacgatg aagttctccg tgcttgtgat aagattcaaa
    29881 tctttaagct tgttgttaaa accattgctc gcaaacacgg actttacgca acatttatgg
    29941 cgaagccaaa atttggtatt gctggatcag gtatgcactg taatatgtcc ttgtttgatg
    30001 cagaaggaaa taacgccttc tttgatccaa atgatccaaa aggaatgcag ttgtcagaaa
    30061 cagcttacca tttcctaggc ggtttgatca agcatgctta caactatact gctatcatga
    30121 acccaacagt taactcatac aaacgtttgg ttccaggtta tgaagcgcct gtttacattg
    30181 cttgggctgg tcgtaaccgt tcgccacttg tgcgcgtacc tgcttcacgt ggtatgggaa
    30241 ctcgtcttga gttgcgttca gtggatccaa tggcgaaccc ttacgttgct atggctgttc
    30301 ttttggaagt tggtttgtat ggtattgaaa ataaaatcga agcaccagct cctatcgaag
    30361 aaaatatcta catcatgaca gcagaagagc gcaaggaagc tggtattaca gaccttccat
    30421 caactcttca caacgctttg aaagctttga cagaagatga agtggttaaa gctgctctcg
    30481 gagatcacat ctatactagc ttccttgaag ccaaacgaat cgaatgggca agttatgcaa
    30541 ccttcgtttc acaatgggaa attgataatt atttagacct ttactaatac taatatagaa
    30601 gaaagattgc ctgtgggtaa acagtcacac agcagtctaa gccatcaaat acctataacc
    30661 cttaaaatag cgatttcggt cgctatttat ttttcgaaaa atcctcttga ctcttttgcg
    30721 aattagattt atcatcagac gtgtagaaga aaattaagga gtcactatgg aaaaattcaa
    30781 tttcaaaaac aatatcgggc aagaaaacaa gttacttcaa atcgaaatct acaagtttac
    30841 taacttttgc aagcttcaaa attacacatc tgtaaatatt ttttcgaaag atatatttga
    30901 agccatagta aattgagact agaatagtac actacatctg ctaaaaattt ctagaaacta
    30961 atttaacttt cctaatcgat ttgtttacat cttatttcaa tctactatat tatctcaata
    31021 aatgatgatg gcgactgttt tgtttgtgct tgtcgatttt tgaatcctga tcgagcggaa
    31081 gaatatttct gccgaggttg ccaaggggaa aatcctgaag atattgaatt ttatgatgaa
    31141 caattacagg cagaaaaggt ggaggttttg aatattcgat tggaagtaaa aaattgaatt
    31201 atctacaatc tcatcaacaa taaacctatt tcaaccccat tatctatagg cgtattttta
    31261 cgccttttta tatacttgaa gcacataaga aacattatgg gaagtttgct gatggaagca
    31321 ctcaagaaat tgatgttcct tatgatattc ctgatacttg ggagtgggtg aggataaaat
    31381 caatttattg gaattttggg caaaataagc cagagaaatc ctttaggtat atagatacgt
    31441 ctagtattga tagaaaaaag aatataatca actacaaaaa tctacaatat ctttcacctg
    31501 aacaagcgcc ttcccgtgct agaaaattag tttcgcagaa tagtgtctta ttttcaacag
    31561 ttagaccata tctaaaaaat attgctgtag ttagagaact taaagagtat ttgatagcta
    31621 gtacagcatt tattgttttg gatactttac ttaacgaaac atatttgaaa tattatttat
    31681 tatcagataa ttttatcaat cgtgttaata ataaatctac tggaacaagt tatcctgcaa
    31741 tcaatgatta
//
LOCUS       DAVKXA010000022        31007 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKXA010000022 DAVKXA010000000
VERSION     DAVKXA010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.022"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(3..650)
                     /locus_tag="VW883_001069"
     CDS             complement(3..650)
                     /locus_tag="VW883_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV0274218.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(759..1277)
                     /locus_tag="VW883_001070"
     CDS             complement(759..1277)
                     /locus_tag="VW883_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0274219.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1504..2373)
                     /gene="rsmI"
                     /locus_tag="VW883_001071"
     CDS             complement(1504..2373)
                     /gene="rsmI"
                     /locus_tag="VW883_001071"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0274220.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQILKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2376..2693)
                     /gene="yabA"
                     /locus_tag="VW883_001072"
     CDS             complement(2376..2693)
                     /gene="yabA"
                     /locus_tag="VW883_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0274221.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2733..3623)
                     /locus_tag="VW883_001073"
     CDS             complement(2733..3623)
                     /locus_tag="VW883_001073"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0274222.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3620..4258)
                     /locus_tag="VW883_001074"
     CDS             complement(3620..4258)
                     /locus_tag="VW883_001074"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0274223.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4478..5275)
                     /gene="proC"
                     /locus_tag="VW883_001075"
     CDS             complement(4478..5275)
                     /gene="proC"
                     /locus_tag="VW883_001075"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0274224.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5279..6541)
                     /locus_tag="VW883_001076"
     CDS             complement(5279..6541)
                     /locus_tag="VW883_001076"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0274225.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAIA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6551..7681)
                     /locus_tag="VW883_001077"
     CDS             complement(6551..7681)
                     /locus_tag="VW883_001077"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0274226.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7761..9656)
                     /gene="cbpE"
                     /locus_tag="VW883_001078"
                     /gene_synonym="pce"
     CDS             complement(7761..9656)
                     /gene="cbpE"
                     /locus_tag="VW883_001078"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0274227.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHLDTKNSNTKNFIKNLSPEIIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQHINAASKDYDATVFDIRQDGLVNISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     RWFYLTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQY
                     KGQWYYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWL
                     KKANDWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVP
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            complement(9659..10546)
                     /locus_tag="VW883_001079"
     CDS             complement(9659..10546)
                     /locus_tag="VW883_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0274228.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10536..10997)
                     /locus_tag="VW883_001080"
     CDS             complement(10536..10997)
                     /locus_tag="VW883_001080"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0274229.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10994..11902)
                     /locus_tag="VW883_001081"
     CDS             complement(10994..11902)
                     /locus_tag="VW883_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0274230.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11895..12092
                     /locus_tag="VW883_001082"
     CDS             11895..12092
                     /locus_tag="VW883_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0274231.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12144..12815)
                     /locus_tag="VW883_001083"
     CDS             complement(12144..12815)
                     /locus_tag="VW883_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0274232.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12869..13090)
                     /locus_tag="VW883_001084"
     CDS             complement(12869..13090)
                     /locus_tag="VW883_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0274233.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13362..14171
                     /locus_tag="VW883_001085"
     CDS             13362..14171
                     /locus_tag="VW883_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0274234.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14352..15227)
                     /gene="aguB"
                     /locus_tag="VW883_001086"
     CDS             complement(14352..15227)
                     /gene="aguB"
                     /locus_tag="VW883_001086"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0274235.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15237..16322)
                     /gene="aguA"
                     /locus_tag="VW883_001087"
     CDS             complement(15237..16322)
                     /gene="aguA"
                     /locus_tag="VW883_001087"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0274236.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPVVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVAIDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16319..17446)
                     /gene="nspC"
                     /locus_tag="VW883_001088"
     CDS             complement(16319..17446)
                     /gene="nspC"
                     /locus_tag="VW883_001088"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0274237.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17446..18705)
                     /locus_tag="VW883_001089"
     CDS             complement(17446..18705)
                     /locus_tag="VW883_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0274238.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18702..19562)
                     /gene="speE"
                     /locus_tag="VW883_001090"
     CDS             complement(18702..19562)
                     /gene="speE"
                     /locus_tag="VW883_001090"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0274239.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            complement(19593..19730)
                     /locus_tag="VW883_001091"
     CDS             complement(19593..19730)
                     /locus_tag="VW883_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274240.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            19817..20532
                     /locus_tag="VW883_001092"
                     /pseudo
     CDS             19817..20532
                     /locus_tag="VW883_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(20498..21973)
                     /locus_tag="VW883_001093"
     CDS             complement(20498..21973)
                     /locus_tag="VW883_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0274241.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            22680..23555
                     /locus_tag="VW883_001094"
     CDS             22680..23555
                     /locus_tag="VW883_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0274242.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNRENASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPDKKQASTNFKPAGQSIEQRSEAINLRLENGYYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHP
                     YASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWM
                     ANLNLKFSVRNKSRN"
     gene            23581..24225
                     /locus_tag="VW883_001095"
     CDS             23581..24225
                     /locus_tag="VW883_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0274243.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(24268..26256)
                     /locus_tag="VW883_001096"
     CDS             complement(24268..26256)
                     /locus_tag="VW883_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274244.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(26258..27016)
                     /locus_tag="VW883_001097"
     CDS             complement(26258..27016)
                     /locus_tag="VW883_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274245.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            27443..27634
                     /locus_tag="VW883_001098"
     CDS             27443..27634
                     /locus_tag="VW883_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274246.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(27988..28260)
                     /locus_tag="VW883_001099"
     CDS             complement(27988..28260)
                     /locus_tag="VW883_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0274247.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(28319..28768)
                     /locus_tag="VW883_001100"
     CDS             complement(28319..28768)
                     /locus_tag="VW883_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0274248.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(28755..30884)
                     /locus_tag="VW883_001101"
     CDS             complement(28755..30884)
                     /locus_tag="VW883_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0274249.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKEFFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         9128 a         6929 c         5678 g         9272 t
ORIGIN      
        1 aactaggatt ctagttttgc aggaagtcta atgtaattct caagctgtga gttcattatg
       61 atttgtaaat ccgatatatc ttcagcagct aaaaacacat tttgaaatgt tccaagtccg
      121 ttttcaccaa aactatattc tctcttacta tacttactct tattattctc tatatagtta
      181 gagtcaaggt tcttaacctc ttgaagttca ttttctttac ttctgaggtt aaaatctttt
      241 acttctgaag ttaagttttt tgacttctgt aagtcatttt cttttacctg aaatatactc
      301 ataaagtctt taacataaat gatgttcggc ttaccaagtc caagccttac tctttcgatc
      361 agtcctattc ctttttttac atcaagctca tctaatgttt ttatggcagt tggctttgag
      421 atatttcttc ttttcataat ttcttcgaca gtaaaataga taaatactct gccttccttg
      481 tctatccagt tattcttaaa tgacattcct gtctgtttaa gaagtatgga ataaaggata
      541 attgcttctg ctgataagcc ccgaaattct tctctatcaa ctaatatctc cggtactttt
      601 aagaagttaa atctttccgc ttctctgtta taaaaatatt caaagtccat gcaagatcac
      661 ctcccttctt aaaaatttgc aaagaaaaag acgatagttt ttcttctatc gcctttggta
      721 accattttta tgaaattttt taaagttaaa aatataattt ataatactat cttcttccat
      781 tttctgattt tagttctgaa agttccaaaa ggtgcaaccg tatttacatg aataaactta
      841 tacacttccc aagtcgctgt tttagtcgct tcatcagccc actttctcat atgcggttca
      901 aataattctt cctcactcaa cgaatcaatc attgcagaga tagaattaat attttcattt
      961 aattttgctt tcaactcttg cagagataaa tgagcgtagg tatctgtgaa ccactgatat
     1021 aattcaccaa gttgattcca tttaaattta tccgatggtg tttttacttg aagccccttt
     1081 ctttcatctt cttcccattt aagaaccaag ttggtccaac caacctgata agcaaggttt
     1141 tctgctggag ttctgtcaac ttcatcagct ctcttatctt ttaaattttc tggaatatta
     1201 tcaaattcta aaatatattt ctcaaatgtt ttctctatct cagcttttag ttcttcttta
     1261 ttttcgtatg ttcgcaaaaa atcaccttct ttctgattta tcaatccttt gatttaaaat
     1321 gaccttattt ttctatttat accttctaag aacgctataa ctgctgctcc aaccatcggt
     1381 attccgtatg ggcttaataa aaaacttaat accaaagctt ctataccaag tgatacatct
     1441 ttatattatc atcactaatt aagttaaaca gaaacagaca gaattattac atcctgtctc
     1501 cctttattgt ttttcttccc agtcgtggta ggcagcgtag agctgacttt tattccactg
     1561 gtaaatctta gcgacttcct tgatagcttg gtttttcttc acaccttgct ggatgcgggt
     1621 ttgaatttct acgaacaagt cttcctcgtc cttttcctcc acaccctgac tggcaccctc
     1681 aacaatgaga agacattcgc ccttgagtgg cgtttcagca atgctttcta ataactcaga
     1741 gatagtacct cgttggtatt cttcatagat tttggtcaat tccctgacca agacaacgga
     1801 gcggtcaccg tagacttcta acatattttc caacgtgtct gctacacgat gaggtgattc
     1861 ataaaaaatc tgagtttcag gatagtcttt tttcgagtcg aaaaattgct tttgctggcc
     1921 tgattttctc ggcaaaaagc cgtaaaagat atgtggctgc ggcgctaaac cactggcaat
     1981 caaggcagaa attcctgcag aggcacctgg aactgtcaca actgcaattt cttcctcaat
     2041 agctgcctta accaaatcat gaccagggtc tgaaatgcta ggcaaaccgg catcagagac
     2101 ctgagcaata ctttgccctg ctttcaagaa accaatcaaa tcaggaattt tttccttggc
     2161 attgtgctca tgaaaactga tctgcttggt ggaaatgtca aaatgcttga gcaaaagacc
     2221 tgtattgcgc gtatcctcag cagcaatcca gtccacttct ttcaagatct ggatagcacg
     2281 aaaagtcata tcatctagat tgccaatcgg cgttgccact agatacagct tgccataggg
     2341 agactgcccc ttaaaacttt tttgaatttg catgcttact ccctgtataa caactcatca
     2401 cagaacatac attcttcgtc ctgctctcga cgttgtccat aaaaatcatt acatacgtga
     2461 aatccatcac ggtaaatacg acggacactt tcgcgaacat gcttggcctt gacgggagcg
     2521 tctgcttcca cctcacccaa gcgttctcgc aacttactat tttccaagcg aagagctgta
     2581 ttttcttcta ccaagctctt gagatttttc ttgatggctt ccacatcggc taaggttacc
     2641 aataattgtt gggaaaaatc atccagcgcg tcaaataatt cttttttgtc cataaaacag
     2701 ccctttcctt tctttatcat tcatttttga gtttatattt ctttcaagac cagatattcc
     2761 atggcatttt gaaagctgac attagcttgc cacatttttc tagcttctag taaatcttgt
     2821 agaatcactc ttactcttac ctgcaagagg tcctgcccgc agagaacttc aagaatccgt
     2881 aaaacctgat cctgtttttc cttatcatct gccaagttgg ctaatttggc aacctgtaga
     2941 taactttctt ttttcttagc tactaaccaa gtcagcaggc gttcactttc atcgaccaag
     3001 gtccaaaaac ttgcctgatt agccaacttt tctgcttcag ctcgcgattg actaaactta
     3061 gctaaaagag tcgctttttt cttaacaagt cccatttgtt ctaagagtaa gataagtttt
     3121 tcttcttgct ttttaaagtg gaagatctga gtccgacttc ggattgtcgg taacatcttt
     3181 tcctcatcgc tagtcaagaa gaaaatataa acttcactct ggggttcttc gatgaccttg
     3241 agcagagaat tggctgcgtt gggatgcatt ttatccgctt gctcgataat aaagacctgt
     3301 tgctggcttt caatccctgc ttgagaaaac tgtcccacca attccctaat gcgttctgtc
     3361 ttgatgacct gattgactgg cttaatcaag gtgacatcgg gaaattctcc ctgttcaatc
     3421 agcttgcaac ttcggcattt ctcacatggt aagacgccaa ctttatccgt acaaaagagg
     3481 ctcttagcta aaaattgcgc tatttccaag cttccaaaga aacctgaaaa gagataggcg
     3541 tgattgagct ggtcttgttc taagatacgg acaaaacggt caaactgagc tggttgccaa
     3601 gcctttagtt gatcttgttt catttggcca agcccattcc gtcaaacaag acagccttgg
     3661 tagtttccac aacttgctcc aaagggagac tagcatcaat cttgacaatg cgatttccct
     3721 ctttatccag aagagaaagg tagccttgac gaactttttt atgcaagtcc aacccttcca
     3781 aatccaaacg attaacctcg cggtcactat tagcagcaat acgagccagc ccttcttcca
     3841 cctcgatgtc aaaatagagt gtcaaatcgg gtttgaggcc atctgtcgca aactgattga
     3901 gccagtcaat ggcttcaata tctaagccac gaccaaatcc ctgataggca acagaactat
     3961 cgataaaacg atccatgatg accaacttgc cagcttcaag ggctggaaga actttttcca
     4021 ccaaatgctg tctgcgactg gcaatataga gaagtagctc tgttttagca tccatctgag
     4081 tatgacttgg atccaaaatc acttcccgaa tcttctcccc aatcaagact ccgccaggtt
     4141 cacgggtcgt caacacctct actccttttt cctctaaaat tggtagcaga gcctctaaaa
     4201 cactggtctt gcctgctccc tctggtccct caagagagac taaaaatcct tttgacatgt
     4261 ctaactcatt tcttttttac tacttctatt ctatcaaaaa aataggggtt tgtgacaatc
     4321 tttttgtctt ctcatttcat actcaatgaa aatcaaagag caaactagga agctagccgc
     4381 aggctgtact tgagtacggc aaggtgaagc tgacgcagtt tgaatttgat tttcgaagag
     4441 tatcaaccac cataaaagag gcagtcaaag ctacctctta tttacctagt tcttgtgttc
     4501 gtttataggc ttgatgaact gcctccatga ctgtgcctcg aaaagcatgc gcttctaagc
     4561 ttgctacgcc agcaatagtc gaaccgcctg gactacaaac ttgatctttc aaaactccag
     4621 gatgttgctg gctttctagg accaattgcc cagctcctac cacagtttgg gctgccattt
     4681 tcaaggctgt ttctcgtggt aatcccgtct gaacacctgc atctgccaag gcctcaataa
     4741 agagatagac aaaggctggt ccacaacctg caagacctgt cgctgcattg attaagcttt
     4801 ctcctaattc aaccaagaga ccagccttgg ctaaaagctg acaaaagatc tcactgtcct
     4861 cagccctgca attaggagac aaggcataac taatcactcc ttgcccgata gaagcagggg
     4921 tattaggcat catacgaata attcggtgtt ggcttgggat aagacttgct agtttttcta
     4981 aggtcaatcc agctgccatc gaaatcaaaa gaagactttc tcttttttca aggatggtct
     5041 ggtattgaga aagcagttca gaaaactgag caggcttaac acctagaaaa atcacatctg
     5101 cttcttcgaa tatttcttca ttgttagaag tctgaccacc gaagttagcg atgaaagcat
     5161 ccaccttgac ttgactacga ttggcaagga gaatctcatc tgacggtcta gcctgcaaga
     5221 cagacttggc taaactagca cccatattcc ccaaaccgat aaatccaatc ttcatctctt
     5281 actcccttat ctgtccatca ccagtgacca catacttgta gctagtcaat tccttcaagc
     5341 ccatgggacc acgcgcgtgc aatttctgag tagaaatccc catttcacaa ccaagaccaa
     5401 attgtcctcc atctgtgaaa cgagttgagg cattaacata caccgctgca gagtccactt
     5461 gatctgtaaa gtatgctgca gcttcagcat tttccgtcac aatggcatcc gaatgatggg
     5521 tactgtggga ttcaatatgc gcaatcgctt cttctaaact gctcacaacc ttaacagcta
     5581 gaatatagtc taaaaactcg gtatcaaagt cttgtgcttg agcagcttga cctgaaacaa
     5641 actggcttgc tttgctatct aggcggaatt gaattggttc caacccagct tcttttcgat
     5701 ctgcaaccaa cacttgctcc aagcgaggaa ggaagcttgc tgccttgtct tcatgaacca
     5761 gcagaacctc catggcatta caaacagaag gacgactggt tttagcattg ttaatgatag
     5821 acagcgcctt gtcttcgtct gcatccttat ccacatagac atggacaatc ccagtccctg
     5881 tctcgataac aggtacaatc gcattctcaa ccactgcatt gatcaagcca gctcctccac
     5941 gaggaatgag aaggtctaga tagcccttgg ccttcatcat agcatagcta ctttcacggc
     6001 tagtatcctc caccagttga atcacatttg gatgaatagt agtcgtctcc aagcccttct
     6061 tcaaggctgt gacaatggca tgggttgttt gataggcatc cttaccacta cgaagaacaa
     6121 ccgcatttcc actcttaaga gtcaaagcag ccgcatcaga cgtcacattt ggacggcttt
     6181 catagataat accgatgaca cccatagcta cacgtttttt tgtgataacc aaaccatttt
     6241 caagctgact tgtttctaaa acttcaccga ttggatctgg taaggcaacc acttcacgaa
     6301 ttcctcttgc catcgcttct atacgatctg catccaaata aagacgatcc aacatcacat
     6361 ctgagatttt ccccttagcc gctgccatat cgagggcatt agccgctaaa atttcctcag
     6421 tagcagccac taagtgatca gccatggcta gcaaggcttg gtttttcact tcttcactag
     6481 ctgtgttaat cgatttttta acagcctgta cctgttcaaa ttgttcttgt ctactcacca
     6541 tagtttacct ctaaaattct gtaaaaagta gttggatttc aggagtaatg gaaatccagt
     6601 cgtcacggta aatcaagaca cccttggctt tttgagaacg caacatatcc tccaaagcag
     6661 atgctccaaa ttgcacgcgt ccttttccaa gtgattttcc actttccttg tcaaatactg
     6721 tcacgatatc accgtaagaa aagactcctt ctgcttcaac gataccagat aagagaagac
     6781 tctttccatg ttgagagaga gcttccgcag cccctttatc aacccaaata gaaccttgac
     6841 tctgagcata gaaggcaagc cattgtttct gggtacgaag ccccttctct tgagcaacaa
     6901 agtaagaacc atcctcggtc tcctctgccg cctcaatcat ggaatctgat ttcaaggatg
     6961 agcagatata aacaggaact cctgattccg tcgcgatagt tgcagccttg attttggtta
     7021 acataccccc agttccgttt gacgaaccag ctccaccagc catatcaata atctcacgat
     7081 tgatggtctc gattctctcc aagcgtttgg ctcttggatc tgaattagga tttccagtat
     7141 agagaccgtc cacatctgtc aagagaacca aaaggtctgc ttggaccatc gccgctactt
     7201 gggcacttag agtgtcattg tccccaacct tgacctcatc aataacgaca ctatcattct
     7261 cattgatgat aggaattgcc ccacggttga gcaaaaccga caaagcctga tgggcatttt
     7321 tataacgacg cttatccaca aagtcatctt gggtcagcaa gatttgtgca gaaacgattt
     7381 gacgcaagag aagattggtt gtatattctt ccaacaaaag cccctgccct accgctgctg
     7441 aagcctgttt atcagcaatt ttagtcggac gctttttaaa tcctaaggct ccaaaaccag
     7501 ccgcaatggc acctgaagac accaaaatca actcatgacc agcctcgtgc agcatagcca
     7561 actgctgggt aatatccttt accttactac gtgataaact tccatcctca tttgtcagag
     7621 aagaagtacc caccttaaag acaatccgtt tgtatttcat agtctcactc cgattattca
     7681 tatttatcca ttataacatg aataacagga aatagaaaag agttgatagg aaaaagaagg
     7741 ccctaaaacc ttcttttcta ctactgttct gattccgatt tgtttacact cgtttcagag
     7801 ctttgtgaag ttgaggatgt caaatcttga ctagttgaag aatttgtaac actttcatgt
     7861 tgactcgttt ctttattttc aagatccttt ttcactactt ctttggattc ttttatttct
     7921 gaatgacttg tagttttaat tgtagcagat ttctcgatcg gaacatccac taaccaggca
     7981 ccacttgaat ccacagtata gccttctggt gtcttaccat tcacaagtaa ttgaccattt
     8041 tctttcaaga agtaccattt atccttgtct ttaatccaac ctatagctcg tgaaccatct
     8101 gtcttgtaga aataccaatc atttgccttt ttaagccagc cttgcttcat agctcctgat
     8161 tcttctagat agtaatgatg tccagcaact tctatctcac ctgtcttcat gataccagta
     8221 gaatccatat agtaccaggc ttctttatct tttacccagc ccgttttcat ttcccctgat
     8281 ggagcaaagt aataccattg ccccttatat tgaagccaac ctgtcttcat agagccatca
     8341 acatccaaat aataccactg ctctttatct tgaatccaac caatttccat ctggttttct
     8401 ttgttaaaat aataccagat tccagcgatt ttcttccaat ttttagcagc aacaccagag
     8461 tctgtcaaat agaaccaacg attgttccat tttttccatt gattctgtaa taagataccc
     8521 gtttggttaa agtaatacca ttcaccctta atttcattcc aaccgacagc atattctcct
     8581 gtagaatcag gcgcttgata ccaccagttt ccatatgaac tcttatgcca accagcttga
     8641 aaacttggaa tcggcttgta ggaagttgaa atgtttacta aaccgtcttg tcgaatatca
     8701 aaaactgttg catcatagtc tttgctggct gcatttatat gttgaattcc cattgattca
     8761 agccaactaa tatattccct atttatttct tgaccgctat catacgaacc aattggtgag
     8821 gaggaagttt gaacaattat ctcaggagac aaatttttta taaaattttt tgtattagaa
     8881 ttttttgtat ctaaatgatg attaaacttc atcaaatcaa cttttccaat gagaggacca
     8941 tacttgtctt ctgctccatg aacattatct aagtcgcccc caaggtaaat tttcttgcca
     9001 ttgactttta ccacactaat caaggaattg gaattatcat cccaaatttt ctttaattca
     9061 cccgatgaat cggtttcatt ttcatagtta tagagctcaa tatccatgtc cccaaactga
     9121 aaatgagcat ccccttgtgt gatattttga ataactgaaa cacctttttc tgaagcagtc
     9181 tgtaaaacct tatcataacc gtacagatta tcccatagac gttcagaatt agtaatacga
     9241 ttatcactat attttttaag atagactcgg tcaactggat aggtagacag taattcatca
     9301 acatttccaa tatgatcact gtgggtatgg gtcaccaaaa taaaatcaag tttttggaca
     9361 cccaattcct tcaaacgacg aaagacacgg tctgttagaa catgcttata agacgtttca
     9421 attccttctc tccatggata gcgagaatca cttccatctg ggaaatcata atcttctcct
     9481 gtatccacca tggcaaaatg tccattgctt tcaagaataa tcgcatcact gccaccttct
     9541 tgaacattga taaagtggat tttatttcct gaactttctt gagcctgaac attcccatac
     9601 catgacaaac ctaaaaaagc gcctacaagt gctaaactag ttaatttctt tttcattctt
     9661 actttctcaa tctctccaag gtttccttaa aaatctctgg gatatctgct ttaaattcca
     9721 aggtcttacc tgttctcgga tgagtaaaac ctaaagtctt ggcatgaaga aattgtccat
     9781 gtcctttcaa agtcttgcga ggaccataga cctcatcacc agcgactgaa tggccgatat
     9841 aagccatgtg gacacggatt tgatgagtgc gccctgtctc cagttgcaac tctactaagc
     9901 tataatcgcc aaagcgttcc aagacgtgaa aacgcgtcac tgcaggcttc cctttagcag
     9961 ttacagcctg tttcttacgg tctttttcac tccggccaat cggcgcttca attacaccac
    10021 gatcattagg cagatttcca tgaacaatcg cccaatattt gcggagagac tttttatcct
    10081 tgagttcttg ggcaagtgct agatgcgcat catcgttttt agcaatcatg agaagacctg
    10141 acgtatcctt atcaatacgg tgaacaatcc ctggacgcag aaccccattg atacccgaca
    10201 agtccttaat atgatacatg agggcattta ctagggttcc actggtatga ccagcactcg
    10261 ggtgcacaac cattccctga ggtttgttaa cgacagccac atcctcatct tggtagacta
    10321 tttctagcgg aagatcctca gccacatact ctaatacctc tggttctggc acatggtaag
    10381 tgacgacatc accctcttgg actgtgtatt tagctttctt gacttgacca ttgaccaaga
    10441 cctggcctga tttaatttgt tcattcgcga gactacgtga taattctgac aaatctgaca
    10501 aagccttatc caaacgcaga ccaccagttt caattttaat ttccatttat ttcctctttt
    10561 agcattgcaa tcaataaaat aatcactcca accgtcagat agctatctgc cacattgaaa
    10621 attgcaaagt tgataaagtc aaggtggaac atatccacaa caaagccctg actgaccctg
    10681 tcaataaagt ttccaagacc acccgcgatt attagagtca aacccaagac catccagaat
    10741 gagtcctcca tgtgtttatg taaataccaa atggcaccta tcacgacaac cagagtaatg
    10801 acagcgaata acagctgctg atcttgtaag atagaaaagg ctgcacctcg attttgcagg
    10861 taggtcaagc taacgaaatt gggaatccag gagcgcactt cacccagtgg aatctgctgg
    10921 acgatatagg atttgaccaa ctgatccagc ccaattaaaa gcagtacaat gactgccact
    10981 attgctcttt ttttcatgat ttcctctttt gatcaaaata ttcttgcatg acttctacga
    11041 agagagtccc agcttgacta agctccactt cttcacgttt aacatagacc atgcggttat
    11101 ctaggttatc cttgagacga ataactgtaa tgccattaac actgtcacta tctaaaaatc
    11161 cagaacctgt cgcataggcg tccgtccgct ccaaaatacc attcaaggtg gcacggtctg
    11221 tcacattaaa catctgtgag ctagcgctgg tatcgacaaa gttctctgaa taataaaggt
    11281 actcgtcttt ctcttgagtg aaacgaaccg ttggtaaatc cgctaaatcc tccatgacta
    11341 attcctcttt ctgagctaaa ggatgaccct cacagagata aatatgggta tggaaaggaa
    11401 tcaattcgat gacctccaga cctaactttt caacccgttg cataatcccc tttttatttt
    11461 gattgttgag gtagataatc ccaatctcac tatgcccttg cgccacttca tctaatattt
    11521 gaacagtagt tgattcaaaa atacggaagt tcttatagtc aggatagcgc tctgaaaagg
    11581 ccgtaatagt tggtggtaag aagtcatagt gctggctagc aacggaaaat tcatcttttt
    11641 cttcttcagg attggcatac tgattttgaa aaatatcaaa tcctttaacc aattcttgcg
    11701 ctttttcata aaattccatc ccacgacggg tcaagaaagt ccctgagctg gtccgacgga
    11761 aaatcttaaa gcccaactct ttttccaaat cacgaacaga aatagacaga ctcggctgac
    11821 taacatacat cttttcagca gcttcacgaa aagtaccact attggcaata gccacaacat
    11881 agcgtaattg ttgaatgttc atcttctacc cccaacttct ttatcttttc attataccat
    11941 attttagaag ttttccaaaa aggaaaaaag aacatcctat tcttcttaac tatcttcact
    12001 atctgccttt ctcacgccaa tcttattttc aaaatcaatt caaaaaaata agtggctaca
    12061 caccacttca gtatcggaaa gaaaaacgtt gactatttgt gaaaaaagaa aatgccggaa
    12121 aattccgaca tttttttagt aagctaactt cctgaaaata ggagtaacca aacatcccag
    12181 aaggcagtga tattgatgag aatatgaact agtattggat agtagagatt tttagtcatg
    12241 cgatacaata gagctaaaat aagacctcca ctagcataaa tgaaaaaagc aagaggagtt
    12301 aaagcaaaat tgatatgaat ataaccgaaa ataatagcag aaagcaaaac atctccgtac
    12361 caaggtgagt ttttgaaaaa ggttgtcata agcacacctc gataaatcaa ttcctcagca
    12421 ataggggcga tgaagcaaac gatgagcaag aaataaggga actcctgtct ccccatcatt
    12481 tctaccgttt cattcaaaga aatctgattt gaagacaggg atatgaaata cgaaaagagg
    12541 aagtcagaca tatatgaaat gatgtagccc agtaaaaggt agatgaagta cctcagctgc
    12601 cacttgaaat gaaaaatttt ctttcctgca aaaaccagta gatagatgac cgctaagaaa
    12661 agaactccgc tctccatcaa aagcagaatc tgaaaaaatt cacgacttgc tggtagatag
    12721 ggctttgcga ggtgattgaa aactctccaa aaccaagttg atttgtaaaa aattaaggac
    12781 aatgctagta aaatttgaat agcccgtttt ttcatattaa attctctgct ttctccactt
    12841 gtttcttcat attactaata aattttactt aaaatctcgc agcacttcct ttgcaaagat
    12901 gattgcctcc tccaatatat cctaaatcat aggtgcctct gggacaaaat ccatgaaccg
    12961 gcagagttaa tactggttct atttcccaat cgtacctacc attaggattt ttaccatatg
    13021 gatctgctcc accttgtatc agctctaatt cttcatttgt tagatttata ttttttgtca
    13081 ttaaaatcat gatatatttc ctccattatt cttcagatta gttgagtaat ctgatactca
    13141 tacctactta caaaaaaact attatattaa gttggttttt taatttgtct agttgcaaca
    13201 ttgacaaaca tagtatagca tatctttgcc aaatatcctc ttcaaatcat gaattgtcat
    13261 caaaacatct taaactataa aatcaattag tctcaagctt tctatcaatt tcttctccaa
    13321 aatatgctat aataatagca aaagataaag aaggaagacc tatgattaaa ctactagcct
    13381 tggatatgga tggaaccctc ctcaatgaag ccaaggaaat cccacaggct cacatcgctg
    13441 ctattcacca agccattgaa aaaggtgtca aactggttct ctgtacgggt cgcccccttt
    13501 tcggtgtcct cccctactac aaaaaactgg gactcgacct ccagaatgag tatgtgattg
    13561 ttaacaacgg ttgttcaact caccagacta gcgactgggg cttggttgac tggcaagaac
    13621 ttagtccagc tgacatcgaa tacctctatg accttgctga aaagagtgat gttcagttga
    13681 cactttttga cgagtcacat tattttgttc tcggtggcaa acccaatcaa gttattgaaa
    13741 atgatgctaa actagtattt tcagacctga ctgaaatttc tcttgaagaa gcgactagtg
    13801 gaaagttacg gatgttccaa ggtatgtttt taggaacaaa agaacaaaca gacgattttg
    13861 agcagcgttt tgctgaagag ctttgccaac gattcagtgg agttcgttcg cagcctgtca
    13921 tttatgaagc aatgccgctt ggaacgacaa aggctactgc tctttcacga ctagctgaga
    13981 ttttgaagat tgattcctca gagattatgg ccatgggcga tgctaataac gatatcgaaa
    14041 tgctccagtt tgcagggctt gggattgcaa tgggaaatgc cagcgattat gtcaaatctc
    14101 ttgcggatgc cgttacctca agcaacgaag aagacggcgt tgcgcgtgct attgagaaat
    14161 atattctata aaaaagaaaa gcaaatagac agaagttact gctatttgct tttttgctaa
    14221 tattttaaaa tacggactaa tcaatagaca agaatagcga atcataaaaa tcgatttact
    14281 agatgccata gtatcttata gttgctaata agaagttagt ctagcagaat gaatctctca
    14341 tttctcccac actaatctgt aatttgtcta tacatttctg gtcttctatc tcgaaacaag
    14401 ccccagttta ggcgttcact tgctcccttg tctaggtcat aagtagctaa cagaacagct
    14461 tcttcttgtc tttcagctcg ttctagaata gctcctgttt catccgtcat aaaggaggaa
    14521 ccgtagaagt caagactgga actctgtccg ccattttcct cactaggagt aacctcctct
    14581 aaaccataac gattggctgc gatgactgga acaatattcg ctgctgcgtg cccttgcata
    14641 gtacgttgcc agtgaccaca actatctgta tccaaaattg gctctgaacc gatagctgta
    14701 ggataaaaga gcaattcagc accattcaat gcaagacagc gcgctgtttc agggaaccat
    14761 tgatcccaac agataccgat accaatctta gcatagcgag tattccagac cttgaaacca
    14821 gtgttaccag gcgtgaaata gaatttttct tgataataat ggtcatctgg tatgtgggtc
    14881 tttcgataaa cgcccagcac ttccccatct gcatcaatga cggcaataga gttatacaag
    14941 acattaccat ctttttcata gaaactgatt ggtaaaacaa cttgtagttc cttagcaatc
    15001 accttaaaat gctgaatggc agtattttcc gctacagatt gggcatactg gtagtagtca
    15061 tactgacgtt cctgacagaa atagggatgt tcaaacaact cgggcaagag aataatttgg
    15121 gctccttgct cagcagcctg acgtactaaa cgctctgcgg tttggatatt tgttgccaca
    15181 tccttagcgc attgcatctg aatggttgca actcttacat ttctcatctt tttctcctat
    15241 tctggaattt gttgggtgat acagtggata ttaccaccac ctaagagaat atctctggct
    15301 ggtattccga caactttacg gtctgggaaa cacttgctga ggatatctat ggccacttgg
    15361 tcgtttacat cctcaaactg tggaaccaag acagccttgt tggcgatata aaagtttacg
    15421 taggaagctg ctagtcgttc acctgcgtat cgctcttctt ctccttcttc atagatgtag
    15481 cctggcaaat cttcttctgt cacaacttgt cgaactacag ggataggcaa tttatgaatg
    15541 gtgaagtgac aaccttttgc atctgtttcc tgttctaaga gttcgagatc tgcttttgac
    15601 atggcatact ggggatcatt ttcgtcatct gtccaagcca aaacaagctc agcaggacca
    15661 acaaaggcag caacattatc gacgtgttca ttggtttcat cctgataaat accataagga
    15721 agccaaataa ctttttcagc accaagactt tctaataatg tgttttcaat ctcctcttta
    15781 gtcaagttag gattgcgacc aggactaagc aagcaacttt cagttacgag aatagttcct
    15841 tgaccatcgc tatggattgc gcctccttcc agtacaaaag gtttagcatc atagacaggc
    15901 ctttccaaag cctcagcaaa acgactggct acttggtcat cctcttcata atcttgataa
    15961 agaccatcat aggtgcctcc ccaagcattg aaggcccaat ccacggctaa tttcttacct
    16021 ttatcattga cgagaatggt tgggccagta tcacgcgccc aggcatcatt ggtgggaatg
    16081 tctaaataaa caaccttgtc tccaagatag gattgggctt cagatagata ggcctgctcc
    16141 accaaaagat agactctttc cccttctgct atggtctcga tgatctgagt aaatgctctt
    16201 ttagcagcct ttccttgaaa aggccatgat cctggtcgag tcggccatat catgagggta
    16261 ccatgatggg gttcgtactc tgctggcatg tgatagccta atttttttgg actgtccatc
    16321 atgataatct ccctttaaag tcttgatagc caaaagcttt gagtaagcta cagtctccct
    16381 gttcgtccat gagatagaga cttggcaatc caataccatt aaaggtatta tttttgacaa
    16441 aagaataaat ggccatgtct tgaaaataaa gtctgtctcc gatttggact ggattttcaa
    16501 aactataatc accaatcaca tcgccagtca gacaggtatt agaagaaagt ctgtaggtat
    16561 gggctttttc ctgtgcctca aagccatttc tcaaaggtgg acgatagggc atctcaagta
    16621 catcaggcat atggcaggtc gcagaggcgt ctaaaaccaa gatttccata ccgttttcta
    16681 caatatctaa tacctcagtt gctaaataac ccgcattaag cgcaatggct tcaccaggct
    16741 cgatatagat ttcaagattg taagtttttc ggatacgctt gatttctgaa atcagcaaat
    16801 ccacatcgta accttctctt gtaatatgat gaccaccacc catattgagc cattttacct
    16861 catgtaagta gggaccaaat tgttcttcta ctgctttcaa agttgtttgt aaatcatctg
    16921 ctccctgctc gcaaagggta tgaaaatgaa gtccgtcaac caaatctagc aaatcactcg
    16981 gaatcttgtc tatagtaact ccaaagcgag aacctggtgc acaagggtca tagagcgcgt
    17041 gatctccttg agttgaacac tgagggttga ggcgcaaacc aacactgaca ccagcctctc
    17101 gacaacgagc cccatgctta cgcaactgtc tctctgagtt aaagacgata tggtctgtta
    17161 tcccaagcaa ttcctccaag tctgcatcct tgaaagcagg cgcaaataca tggacttcac
    17221 caggaaattc ttcccttgcc aatttggcct catagagtcc actagctgtc gtacctgata
    17281 gatactggct aatcaaggga taagttttgt agagggaata tgccttctgg gcaagcaaga
    17341 ccttgcaacc ggcctcttct tgtacatatt gtagaatgcg gcaattagct tctaacttgg
    17401 ccaagtcaat aacataggct ggtgttggta cttgttctaa cttcattagt ccaccatttg
    17461 tggattttca accacaaccc atggcaaacc atactcattc aaagcttcca tgaatggatc
    17521 tggatctaac tcctcaaggt tatacactcc agcttgtttc caagttccgt tcatgactaa
    17581 ttttgtccca atcatggctg gaactcctgt cgtataagaa atagcttgcg aaccaacctc
    17641 tgcgtaacat tcctgatggt cgcagacatt gtagatatag atagtctttt tgacaccgtc
    17701 tttgacacct gtaaagatac atccaatatt ggttttacct acagtacgtg ggccaaggct
    17761 agcaggatct ggaagcaagg ctttcaaaaa ttgaattgga acaatttctt ggccgttaaa
    17821 gttaatggta tccgtacgaa ggagtccaac attttcaaga catttcatgt gcgtcaagta
    17881 agattgacca aaagtcataa agaaacgaat gcgtttgaca cctggaatgt tcttggccaa
    17941 tgattcgatt tcttcatggt gaaggagata catatctttt tgtccaactt gagggaaatc
    18001 atactcacgc ttgatagaca tagcttcgac ttcgacccat ttcccatctt cccagtaaga
    18061 acccggcgca gaaacctcac ggagattaat ttctggatta aagttggttg caaatggata
    18121 accgtggtca ccgccattac agtctaaaat gtcgatataa tggatttcat caaaatagtg
    18181 tttgagggca taagctgaaa agacactagt tacacctggg tcaaaaccag aaccaagaag
    18241 agcagtcaag cctgcttctt tgaatttctc ttgataagcc cactgccatg agtagtcaaa
    18301 gtaggctgta aaaccaagtt ccttacaacg tttttcgtag atagcacgcc actcagggtc
    18361 ttctgtgtct tctgcttcgt agttggctgt atcgatatag tgaacacctg ttgccaaaca
    18421 agcatccata atggttaaat cttgataagg cagagctaca ttcaaaacag cttctggttt
    18481 gtagctttca atcagagcaa tcacttcttc aaccttgtca gcatcaagag cagctgtctc
    18541 aatctttgta cttgttttgc cttccagttt agctttcaag tcatcacatt ttgacttggt
    18601 acggctagca atcataatct ctgtaaatgt ttcgctatct tgacaaatct ttgaaatagc
    18661 aacttgggca acgcccccac aaccaataac tagtaaacga ctcatttttt tccttcctct
    18721 tcttctaaaa tgtcctcaac atacttgggc aacataaagg ctcccacgtg taagtttgca
    18781 gtgtagtatt ctgtgaaaag ctggcgtttt ttccaacctt ccttgtcaaa atctttgaca
    18841 gggtggtatt ttttcgatgc aaatccaaac aaccaatagc cagctgggct agttggaata
    18901 tgggcctgat aaacccgact gattggaaag gattgattga ccttgcggtg catgcttcgg
    18961 caggccgact catcctcgtc aaagaaggga ctcccatgct gataaatcat gatgccgtct
    19021 tccttcagag ctcgataact attgccgtag aattccttgg taaagagtcc ttccgtatgg
    19081 ccaaatggat ctgtcgcatc gttgatgata atatcgtaat catcttcgca gtttcgcaaa
    19141 aagcgtagcc cattttggta gtaaatggta acacgaggat catctagccc tgcagcaaag
    19201 tctgggaaat actcacgaca gacctcgacc aacatctcat ccggttccac gatatcgatt
    19261 tgttccagtt caggatagag tgttaatact tgggcaacac cgccgtcacc acccccaata
    19321 accaatactt tctttggatt tgggtggaca gccatgggaa cgtgaacggt catttcattg
    19381 tagacgaaat catccgcatc tgagaacaag acatggccat ttaaaatcag tattttccca
    19441 aaagctggcg tatccaagac ttcgatatcc tgccattcac tttttccagc gtaaagttgc
    19501 ttggctgttc tcagagacaa tttgacatct ggagtatgaa cttcagaaaa ccataaatcc
    19561 atctatttct ccttatatta tatttagcgc agttagctac tgccaaagcc caagtggtat
    19621 acttggaata agccactgtg gattagttca tttcctccaa tcgcttgacg atttccgaaa
    19681 ggctctaacc acagcttttg tttcaattgg taatgagttt gataacgcat agacgtttta
    19741 tctcgtctaa ggtaacaagg caaaaagttc gtggataacc aagtagactt gaaatactac
    19801 atctggaggt actcccatgc tttatgtggg cattgatatc gctaaaaata aacacgatgt
    19861 tacagccttg aatgttcaag gaaaaactgt tcttaaacca ctcacttttt caaataataa
    19921 agctggtttt gaactcttag atctgtctct tcgacagctc aaccaagact gtctcatcgc
    19981 tcttgaagat actggacatt atgcctttaa tctactgaac ttcctgcatg aacaaggata
    20041 taaagtttac acctacaatc ctttgctcat caaggaattt gccaaatcat tatcacttcg
    20101 caagactaaa acggataaga aagacgctca tggcatcgct cttaaacttc tttctgaccc
    20161 caatcgtgaa caatttcaac acgataatcg gcaagtagac ctaaaaatac tggctagaca
    20221 tattcatcgt ctcaagaaaa acagtctgat tggaaagtac aatacactcg ttgtcttgat
    20281 atcatctttc ctgagttgga taaaatcgtt ggaaagcatt cagaatatac ctaccaactc
    20341 ttgacacgct accctaatcc tcagaaaagg attgaggcag gatttgataa gctgatagaa
    20401 attaagcgat tgaccacttc taattcaagg gctttttgcc gtgctctaaa atcatcgcca
    20461 aatcatcaaa ttgaaataag aaatagttta gataaaacta ttgacttttc ttatagtttg
    20521 tctttctctt aataacgttg atatgattga cctctggatc ttccgtccct tggagggagc
    20581 aaccacgttc cttggcgaat tggatatagt ctacaatttc tcgtgtaata cgttcaccag
    20641 gagccaagat aggaatccct ggaggatagc acatgacaaa ttctccacag acctgtccaa
    20701 cagactcatc taaggtcaaa ctttttcttt ctgaatagaa ggcttcttgc ggagacagca
    20761 ctaactcggg ctgaatatat tctcctgcta tcaaatcttt tccatctctt gaatagagtc
    20821 tcttaatatc agccagagca ccaaccaagc gctcgatgtc ttggatgcgg tcgccgatgg
    20881 aaatataggc caagatattg ccgatatcac caaactcgat ctgaatgtcg tattcgtctc
    20941 gcaagaggtc ataaacctcg atacctgtta agccaatacc ctgagtgtaa actgacagct
    21001 tagttacgtc aaaatcgcaa accgaaacac cgtctattaa ctcttttgag taggcatagt
    21061 agccaccgat agcattgatt tcacggcggg catactcaga tagctcaatg acttcctcaa
    21121 acgactcttt accacgaagg gccaagttgc gacgtgaaat atccaaacta gccatcaaca
    21181 agtaagaggc agatgtagac tgggtcaggt taattatctg acgaacgtat tcagaattca
    21241 tctgctcccc gataagtaaa atggagcttt gggtcaaact cccaccagac ttatgcatgg
    21301 aaactgctgc catatcagcc cctgcatcca tagcagaaat tggaagttta tcagtgaaat
    21361 gcaaatgcgc tccgtgggct tcatctacta aaaccatcat gccagcttca tgagccattt
    21421 ctgtcaaccc ctttaggtct gaacagatgc cgtagtaagt aggattgttg attaggatag
    21481 ccttagcatc tggatggtcc tttatggcct gtgctactcg gtcattttca agacctaaag
    21541 cgataccaat cttaggatct acactcatct cgatatagat gggaatggca ccacatagaa
    21601 ccaacgcatt gatagcagat ttatggacat ttcgtggcag aataatctta tctcctgcct
    21661 tgcaggttgc cagaatcata gtctgcaccg atgaagttgt tccaccaatc attagaaagg
    21721 catggctagc tccaaaagca tctgcagcca gctcctctgc atcacgaata atcgaaatag
    21781 gatggcctaa attatccaag ggtttcatcg aattgacatc aatgcctaca catttttctc
    21841 ctaagagttc gacaagttct ggatttcccc gtccacgctt gtgacctgga acatcaaagg
    21901 gaacaatcct tttcttgcgt aacttcacca aggcctcata aattggggct tggttttgat
    21961 ctaactcttt caaaacatac tcctttcaat atttttagga ccttatgaaa actaaggaac
    22021 taaaggttga ctcatgaaaa aagagcaggt tttcacctgc tctgcaatct tctgacgtgt
    22081 ttattttggt ttctgttgag tatgtctgtt cccgatgttt cctaactctc tagtagcaaa
    22141 tattacgtac tttattgatc gtttcacaag atgacgtgtg ctttcaccac actaaaaatt
    22201 tatgaattag gacaagtgtc ctaacatcaa cttataaaag taggctttta accctatcaa
    22261 taatgtggct tttcaaccac gcttcggcat tcaaccctgc ctgtccgtag gcatttttta
    22321 ctcgggttta tatttgctag aaaacatcat ctcattttct aagctttatt actatatcat
    22381 gtttttaaga acttgtaaag tattttttga taaaaaacaa aaatatagta gattgaaact
    22441 agaatagtac acctctgctt ctaaaacatt gttagaaata gattttactg tcctgatcga
    22501 tttgttctgt tcttgtttca ttttactata tgttcgtaaa tgaaagttct ataatgaagt
    22561 tagccaccca gccctcctaa aaattagatg gttcaactag ctgatagctc ttgtaggtat
    22621 aagaaaacac ctctgtgtta tacttgttgt tcaaccacaa acacaagaaa ggcacagaga
    22681 tgcaagacaa ttatactaca aaagccaaac atttgacaat cgatagccgt cgcttaatcg
    22741 aaagatggaa aaaagaaggg aaatcaaata gagaaaatgc ctctctactt ggaaaagctc
    22801 ctcaaactat ccacactgaa atcaagcgtg ggacagtccg acaatgtctt ggaaaagggc
    22861 gcttcaaaga ggtttattct gccgactatg ctcaacagtc ttatgaaaac aatcgcaagc
    22921 gctcggtcaa gaaatcaagc ttgaccaagg aactaaagga aaagattctc cactatcata
    22981 accaaaaatt ttcgcctgat aagaaacagg ctagcaccaa ctttaaacct gctggtcaat
    23041 ccatcgaaca gcggtctgaa gctatcaatc ttcgcttgga gaatgggtat tatgagattg
    23101 atacggttct acttacgaga gcgaaaaact actgcttgct tgtcttgacg gatcgaaaga
    23161 gtagacatca gatcatccga ttgattccaa ataaaagtgc tgaggtggtc aatcaggctc
    23221 taaaactcat cttaaaacaa cacaagattc tttccatcac ggcagataat ggaacggaat
    23281 tcaatcgctt gtttgatgta ttttctgagg agcacatcta ttatgcgcac ccctatgcct
    23341 cttgggaaag gggaactaat gagaatcaca acaggctcat tcgtagatgg ttacctaagg
    23401 gaaccaagaa aatgactccc aaagaagtcg cattcatcga aaagtggatt aacaactatc
    23461 ctaaaaaatg cttggactac aagtcaccca gagaagactt ctggatggct aacttgaact
    23521 tgaaatttag cgtcagaaac aaatcacgaa attgattcaa attttgcagg tcgtttaaat
    23581 atcctgcgtg cgggtgttct tgatgctaac gatggaatta tttccattgc tggtgtggtt
    23641 atcggagttg ccagtgccac gagcaatatc tggattatct ttttatcagg ttttgcggct
    23701 atcttagctg gtgccttttc aatggctggt ggagaatatg tatccgtttc aactccaaaa
    23761 gataccgagg aagctgccgt ttcgcgagaa aaactcttgc tagaccaaga tagggaacta
    23821 gccaaaaaat ccctctatgc ttcttatatc caaaatggag aattcaaaac ttctgcccaa
    23881 ctcttgacta ataagatctt tcttaaaaat ccactcaagg ctctggtaga ggaaaaatat
    23941 gggattgagt atgaagaatt taccaatcct tggcacgctg ccatttctag cttcgttgcc
    24001 tttttcctta gaagtttgcc tccaatgctg tcagtgacca tttttccaag tgattaccgc
    24061 atccctgcta ccgtccttat cgtcggtgta gcccttcttc tcactggcta cacaagtgct
    24121 agacttggaa aagccccaac caaaacagct atgattcgga accttgctat tggtctctta
    24181 actatgggag ttacctttct gctcggacaa cttttcagca tttagaaaac aagaaatacc
    24241 tcgattttga agtcgaggta tcttttttta catttggaca atcttacgat aacttcttga
    24301 agtaatcatg aaaatcagca cataggcgat gaggaagata gcgcagatag acaaggtcac
    24361 aatcaacatc atagtcgtat ccagtacacc aatcactttt aaaatcagac taagcatatg
    24421 gtaggcaaag gctagatgta ggaaggcaaa gagcaaagga aggaagaata cagttaaaac
    24481 ctgtttgttg atggtttgct tgatttgctt ttgatctaaa ccgactttct gcaagataat
    24541 aaagcgctca cggtcttcat atccttcaga aatttgtttg tagtagatga ccagaacggt
    24601 tccgaccata aagataatgg ataagaaaat accgataaag aagacaccac caaagagggc
    24661 actcatctga gcactagcat ctgctagagt gctaccatac acatagttac cttcagtgtt
    24721 taattgagca ttaaactttt gtaagtattt ttcatactcc tcagcgacct tgagttgttc
    24781 tgcttcactg gcatttacat tcataccacc gtaaaactga ttatagatag ccgaatctgg
    24841 gaattgatcc aaaaaggctt gtaaatcagg tacaacaagg taattgtaat cagcagtcaa
    24901 aatattaaac tgatttggaa catggttgac aataaaatct ttagtaaatt cttcttttac
    24961 agaaaattga tgatcattta gagttagagc tttctgttct ttaactccct cattctttgc
    25021 aaagagtccg acctcatttc ctgatagaga cagtttttga ccagtcatat tttcataatc
    25081 tttttggtca aataccatga aaactgtttt tggttggaca cggttttgtc ctttttcaaa
    25141 aatagttaac ttggttcctt cttgattcgc aacagcaaag taagtgtaac gaaatacttc
    25201 tttttcttta atcttataac ctttgtcact tgcaaactgg ctcaagagtt tgtccaagtc
    25261 ttctttttca acattttgcc ctgaaacccc aaaatcatga ggatttagaa cttttttaaa
    25321 gctttctgag gaattgaaaa tgcttgtcgc tgctgacatg gttaccaaaa ccattgttga
    25381 caagatagcg atggtggcta gtccaactgc atttttcttc atacggaaaa tcaagttaga
    25441 aacagatatg aggttatttg gttggtaata gtatttctta tttttcttta agatttggag
    25501 gaaaacggta atccctgcat taaacaagag ataagtccca aagataacca gtaaaacagc
    25561 tatgaagaag gttgttaagg ctgtaagagg atcttttacc gtaagggcaa gataatagcc
    25621 aattcctaaa cttatggaac caagaatggt ttggagagga aggaagcgac cttttttctc
    25681 tccactagct ttctcacgag agagctggag ggcattcata cgggcgattc gaagggcatt
    25741 caggaacatg aggcctagga aaatcaaacc gaagacaaca agcactgtaa tgacaacttt
    25801 cgtctggaag gtagcaacca gctcaacctt caatttcatt agtttgagca ggaaagcgaa
    25861 aattaacttg tcaaacaagg ctccaatacc gatacccgct ccaacagtta gaatcccaaa
    25921 taccactaac tccttaaagg tcatactgat aagatgacgc ttctccaagc ccaacatgcc
    25981 ataaattcct agttccttgg aacggttctt catgacaaaa ctattggcat agagaacgat
    26041 aatggctgac gcaagggtga cgacaaacat accaaatcca agtgtagcct gaatggttgt
    26101 tcctccacgg atttccgcaa tcttaggatt gaaggttaga gagtaaaaga gataggtgac
    26161 agtgactgcc aagagaacag ccagcgcaaa aggatagtag agtttgcggt ttttaatcaa
    26221 gttcgatacc gctaacttat tggttaatcg aaacatacta attcacctcg cttgccatga
    26281 cagtcaaggt atcagagatt tcttggaaca tctgacgttc tgtcttctct ccacggtaga
    26341 tttgattgta aagaatgccg tctttgataa agagtacacg tttagctctg ctagctgctg
    26401 ctgttgagtg ggttaccatg agaatggttt ggccgcgctc attgatttca tcaaagacat
    26461 caagtaaggc tgcagatgac ttggagtcaa gagctcctgt cggttcgtcc gcaaggagaa
    26521 tttcaggttc tgtgatgatg gcgcgggcta ctgctacacg ctgtttctga ccaccagaaa
    26581 tctcgtaagg gtacttctct tgtaattggt ttattcccag attctcagct gtcaccacca
    26641 atttcttcat catctctgta ataggtcttc ttgacaagac aagcggaagc aagatattgt
    26701 cctttacaga tagagtatct agcaagttaa agtcttggaa gacaaagccc aacttttcac
    26761 gacggaagct agaggcctgt gaatttttaa tggttgcggt gtcagttcca ttcaagtaaa
    26821 cctgaccacg acttggttta tccagcatag ctagaatatt gagaagagtt gatttaccag
    26881 aaccagactc acccatgatg gcaacgtagt cacccttttc gacggtaaag tgaatatcct
    26941 tgagggcttc tacttggttg ccctgaaaac gtgttttata aattttttga acgtgtttta
    27001 catctaaaag tgtcatgaga atctcctttc ttaatatccc atcaaatgaa atgtagcttg
    27061 catcatagtg catcccagct gaacgcgctc aatttctttg tgacttggtt ttctagtttt
    27121 cttatgtaag atttgtttca tgatgttact cctttgttct ttatgagtct agtttacatc
    27181 aaaaaaagac cgcttgccat aacctaacct tacaaaagag actttaatct tacatttttg
    27241 taagattggg tgaaatataa gcaaaattac ttagaaaatg atttgatttc ctatttttaa
    27301 agttgtaaaa tataagtgtg aaaaggctta ctttgaaagg aggaagcggg aactaacatt
    27361 ttagtaaggt tacctagata acataccatt caatttaaca cttgcaagtc gttcaaccta
    27421 taaggaaaga aggtgcgctt taatgaaaca caaagaacat atactcatcg gacttctcta
    27481 tctgctctct ccattcatcg gtcagctctt agttgaacac acacacttta tcggtacaga
    27541 atttaccggc actgcttatg ttatttgctg gttatcagtt gttatcagca tccaccattt
    27601 ttccaaaaat gtattgtctc agcagcaaaa atagattaaa aaactgagtt taaattactg
    27661 cttttataat aaaatgaaat aagaacagga caaatcgatc aggatagtca aatcgatttc
    27721 taacaatgtt ttagaagtag aggtgtccta ttctagttcc aatccactat agtttgtgga
    27781 tgaagctggc gaaatattat taatactatt caaaaatcaa agtgcaaact atgtcaactt
    27841 cacattgccg actaaattac agcctgtggc tggcttccta gtttgcactt tgatttttat
    27901 tgagtataaa agtaaaaaag ctttaaatca agcagtttag actattgatt taaagctttt
    27961 tgcttattcc aaatcttctg tagaacctca ccaaaaccag ccttcattgt cgtcaatggc
    28021 ttgggcttct ttgcgtttac gtgggcctgt tccgtacatt tctgcttcga tttcttcctt
    28081 ggtaggcatg atagaagcta ggatgatata gataatcacg ccaagtccaa agtttgcaac
    28141 tgtaaaaata gcaaacaaga aacgaactag ggtaacatca aaattccact tgtctgacag
    28201 acctgccaga actcctgaaa tcatgcgatt gcgtctcatt ttataaaatt tactgttcat
    28261 gatatttcct ctttctgcta ggttagacat agtatatcac ggggaggctc ggctttcatc
    28321 agtcctcagg ctgatttatc agaagcaatt tacctcgaca aagtccacag cgatagcgtt
    28381 tggtatcaat cctacgcttg cgctgatacc tttgctggca ggattgacaa cgataaagct
    28441 tgagtggttt agagttacta ttgggcaagg atggtacaaa ccgtaatcca tccactgctt
    28501 tcaaaagttc cttaaaatcc cgatccttgt gttgatagcc cttcccttgg aaataaaggt
    28561 gataatgaca gagttcatgt cggacaattt tcctaaaaac ctccataccc agtttctgat
    28621 aaaccttggg attaaaatcc agatgcccat ctttggggaa aaatcgccca cctgtcgaac
    28681 gtagacgcct attccactgg acatgatgga taaaaggtct gccgaagtct tctagtgaaa
    28741 cctgcttgac ataatcagtc agtttcattt ggagcgagga gcgacagatt aactttttca
    28801 cgttcagtat caattttctt gacccaaacg gtcaccaaat ctccaactgc caccacttga
    28861 ctagggtgtt tgataaactt gcgactcata tgagaaatat gaatcaagcc gtcctcgtga
    28921 atcccgatat caacgaaggc accgaagtca acaacgttac gcacaacacc ttctagcttc
    28981 tgacctacca ctaggtcttt gatatctagg acatcttggc gaagcacagg tgcgtcaaag
    29041 gaatcacgga aatctcgacc tggtttgaga agatctgcaa tgatatcttt aagggtttct
    29101 ggaccgaggt ctagctcttg agccatttcc ttgactgaaa gggacttgag tttgctttgg
    29161 gcttcttcgt ttaggtcttt aatatctaaa cgtttgaaga attccttaac ggcagtgtaa
    29221 ttctctgggt gaactcctgt attatcaagg atattgctac tttcagggat acgaaggaaa
    29281 ccagcagcct gctcaaaggc cttggctccc agacgaggaa ctttcttgat ttgggcgcgt
    29341 gaagtgattt ttccttcttc ctcgcggtat ttgacaatat tttcagagat agttttgttg
    29401 agtccagcta cgtgtgaaag aagagctggg ctagctgtat tgacattgac accaacttgg
    29461 ttaaccactg tatcgacaac aaagtccaga ctctcagata gtttcttctg actgacatcg
    29521 tgttggtatt gaccgacacc aattgactta ggatcgattt tgaccaattc cgcaagagga
    29581 tcttgcaaac gacgggcgat agaaatggca gagcgttttt caacggtcaa gtctggaaac
    29641 tcctgacgag caagttcgct ggcagaatag acagaagcac cactttcatt aacgataaca
    29701 tagctgactt cagggaaatc tttcagaact tccgctacaa aagcttcact ttcacgactg
    29761 gccgttccat ttccaatggc aataatctct acaccgtatt gaccaattaa atctgctaaa
    29821 tctttcttgg cttcttcgat ttgacgagct gatgctggtt taacaggata aataacctga
    29881 gttgtcagca tttttcctgt tgcatccacg acagctaact tggcacctgt acgaaaggct
    29941 gggtcaaatc caagaaccac gcgccctttc agtggagcaa ccaagaggag attgcgcaga
    30001 ttgtcagaaa aaagttggat agctccctct tcagctttct cagttaattc tgtccgaata
    30061 cgacgctcaa tagcaggcaa gacctttttc ttaacggatt gctgaacaac ttcatcaata
    30121 taagcatttt tcaccttgaa acgagtagca aagaaggcaa gaatacggtc cgtcgcatgt
    30181 tcaaaaccga tcttcaagac accaagtttc tccccacgat tgagagccaa ggtacgatag
    30241 ccttgcatag ttccaactgt ctctgaaaaa tcataataaa tctgaaaaac ctgcttttca
    30301 tcaagacttt catccttggc ttgagaagtg agtttagagt gtctcagcac ttcctgataa
    30361 gtcatagaac gcaaggtcac atcttccgat aaggcttcga ccaaaatatc aactgcaccg
    30421 gtcaaggctt ccttgccagt cgcaaatcct tcacagacga acttttcagc ttctttctct
    30481 aagtcaacta tattctgcaa aatcaagcga gcaagaggaa agagtccagc ttcacgggca
    30541 atggttgcct tggtacgacg cttttcctta taaggaagat agagttcttc aacgtctgct
    30601 aatttttcgg caactaagat agcttcttcc aattccttgg tcaacttacc ttgttcttga
    30661 atcttagcta agacagcttc cttacggtca ttgagatttg tcagactttt atccaaatca
    30721 ataatagcct taatcgccac ctcatccaga ctaccagtca tgtccttgcg ataacgcgcg
    30781 ataaagggaa tagtcgcccc ttcagctgtc aaacttagaa cggtatcaat ttgctttaac
    30841 gtcactccca aatcctgaga gattttttca tattttttat ccataaatct attataccac
    30901 aagctggaag gctttctcca atccttttca tactcaatga aaatcaaaaa gcaaactagg
    30961 aagctagccg caggctgctc aaaatactgt tttgaggttg tggataa
//
LOCUS       DAVKXA010000023        29513 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKXA010000023 DAVKXA010000000
VERSION     DAVKXA010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.023"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(131..1492)
                     /gene="dnaA"
                     /locus_tag="VW883_001102"
     CDS             complement(131..1492)
                     /gene="dnaA"
                     /locus_tag="VW883_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0274250.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1705..2463)
                     /locus_tag="VW883_001103"
     CDS             complement(1705..2463)
                     /locus_tag="VW883_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0274251.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKKQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2521..3702)
                     /locus_tag="VW883_001104"
     CDS             complement(2521..3702)
                     /locus_tag="VW883_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0274252.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3885..4364
                     /gene="rlmH"
                     /locus_tag="VW883_001105"
     CDS             3885..4364
                     /gene="rlmH"
                     /locus_tag="VW883_001105"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0274253.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4408..4481
                     /locus_tag="VW883_001106"
     tRNA            4408..4481
                     /locus_tag="VW883_001106"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4442..4444,aa:Arg,seq:tct)
     gene            4646..4771
                     /gene="comC"
                     /locus_tag="VW883_001107"
     CDS             4646..4771
                     /gene="comC"
                     /locus_tag="VW883_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0274254.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            4792..6117
                     /locus_tag="VW883_001108"
     CDS             4792..6117
                     /locus_tag="VW883_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0274255.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6114..6866
                     /locus_tag="VW883_001109"
     CDS             6114..6866
                     /locus_tag="VW883_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274256.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6918..6989
                     /locus_tag="VW883_001110"
     tRNA            6918..6989
                     /locus_tag="VW883_001110"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6951..6953,aa:Glu,seq:ttc)
     gene            6995..7068
                     /locus_tag="VW883_001111"
     tRNA            6995..7068
                     /locus_tag="VW883_001111"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7029..7031,aa:Asn,seq:gtt)
     gene            complement(7109..7651)
                     /locus_tag="VW883_001112"
     CDS             complement(7109..7651)
                     /locus_tag="VW883_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0274257.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7829..9390
                     /locus_tag="VW883_001113"
                     /pseudo
     CDS             7829..9390
                     /locus_tag="VW883_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(9420..11972)
                     /locus_tag="VW883_001114"
     CDS             complement(9420..11972)
                     /locus_tag="VW883_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0274258.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEVIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12034..13656)
                     /locus_tag="VW883_001115"
     CDS             complement(12034..13656)
                     /locus_tag="VW883_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0274259.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13862..14887
                     /gene="trpS"
                     /locus_tag="VW883_001116"
     CDS             13862..14887
                     /gene="trpS"
                     /locus_tag="VW883_001116"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0274260.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            15039..16517
                     /gene="guaB"
                     /locus_tag="VW883_001117"
     CDS             15039..16517
                     /gene="guaB"
                     /locus_tag="VW883_001117"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0274261.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16568..17665)
                     /gene="recF"
                     /locus_tag="VW883_001118"
     CDS             complement(16568..17665)
                     /gene="recF"
                     /locus_tag="VW883_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0274262.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(17668..18036)
                     /gene="yaaA"
                     /locus_tag="VW883_001119"
     CDS             complement(17668..18036)
                     /gene="yaaA"
                     /locus_tag="VW883_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0274263.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18195..19445
                     /locus_tag="VW883_001120"
     CDS             18195..19445
                     /locus_tag="VW883_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0274264.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYPSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            19442..20725
                     /locus_tag="VW883_001121"
     CDS             19442..20725
                     /locus_tag="VW883_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0274265.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20767..21588
                     /locus_tag="VW883_001122"
     CDS             20767..21588
                     /locus_tag="VW883_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0274266.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21599..22144
                     /gene="pgsA"
                     /locus_tag="VW883_001123"
     CDS             21599..22144
                     /gene="pgsA"
                     /locus_tag="VW883_001123"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0274267.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22141..22968
                     /locus_tag="VW883_001124"
     CDS             22141..22968
                     /locus_tag="VW883_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0274268.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            22953..23792
                     /locus_tag="VW883_001125"
     CDS             22953..23792
                     /locus_tag="VW883_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0274269.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23785..24579
                     /locus_tag="VW883_001126"
     CDS             23785..24579
                     /locus_tag="VW883_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0274270.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24638..25456
                     /gene="mreC"
                     /locus_tag="VW883_001127"
     CDS             24638..25456
                     /gene="mreC"
                     /locus_tag="VW883_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0274271.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25456..25950
                     /gene="mreD"
                     /locus_tag="VW883_001128"
     CDS             25456..25950
                     /gene="mreD"
                     /locus_tag="VW883_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0274272.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26044..27222
                     /locus_tag="VW883_001129"
     CDS             26044..27222
                     /locus_tag="VW883_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0274273.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27446..28225
                     /gene="rpsB"
                     /locus_tag="VW883_001130"
     CDS             27446..28225
                     /gene="rpsB"
                     /locus_tag="VW883_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0274274.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEAGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            28304..29344
                     /locus_tag="VW883_001131"
     CDS             28304..29344
                     /locus_tag="VW883_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0274275.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT         9397 a         4687 c         5872 g         9557 t
ORIGIN      
        1 agaaagataa tagtaataat agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt
       61 catatcaagt tttttagctt gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt
      121 tatccacaaa ttatttgatt ttctttttga ttgattcaat ttctaaacgt aaattatcgt
      181 cttgatcaat caaagatttt attttggcat gggcatgaat gactgtggta tgatcttttc
      241 ccccaaattc cttcccaatt tttggaagac tattatctgt tagttctcta gataaataca
      301 tggctacttg acgggccaaa acaatatttt gaaggcgtct acttcccttc atttctttga
      361 tactaacacc ataaaagtta ccaacttcag tttggatttt atcaattggg atgacgagca
      421 tttggctaac atcttgtttg cgggctctaa tggcttctgc agcaatatca atagtgatat
      481 ccttgatttt ttttactctg gcaattaaag tgatgtcgtt gatggctccc tcaagatctc
      541 gaacatttga atcaaattgc ccagctaggt attctagagt atcactttgg aaattgtagc
      601 ctaaatgttc cgtcttactt tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga
      661 tagtttgtgt caatccccaa ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat
      721 gttttggact acgatcactc gttaggacaa tctgtttttg cttgtcatga agggcgttaa
      781 aggtattgaa aaattcttcc tgagttgcga ctttttttcc gctgagtgac tgtatatcat
      841 cgattaacaa aagatcaaga ctacgatagg tctttttaaa cttttccatt tccccaagtc
      901 ttaggtgatc aagaaagtca ttaataaagc tttcggcagg gatatattta acacgcgcat
      961 taggaatatt ttttagaatt tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc
     1021 ctggtcctcc atagataaaa agagggttat aggtcagagc caaatcttca gagacagcta
     1081 aagcggctga tacagcccaa acatttccat ccccttgaat aaagttatca aaggtatact
     1141 tttcttttaa tcccgtatct gaataaggaa tagatactaa ctttggacta tagtcataaa
     1201 gagttaaatt tgtagcttct tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa
     1261 tatagtgggg agttatttca gcgtcataaa tttcaaaacc agctactaca ataatatctt
     1321 ttagttgttt ttcccagacc atttccattt cagagcgagg tagaaatata gtggcaacat
     1381 tttcctctac cttgatgagt tcagcttgaa tagcatagaa atcatacatg gatcgagtca
     1441 gtctttcttg tgcaaattct aatatacgat tccaaaattg tttttctttc aattctttct
     1501 cctcctttac tatttaaaag tttaatacta gagatatttt accatagata gcaagaattt
     1561 tccacaagct gtgaaaaata atccacaatg ttaccaaact ttatccacag gttggggata
     1621 aaagaagaaa ttattgattt attaagcttt ttatcgaaaa acatagtgga taaccttgtg
     1681 agataaaaaa ataaaagaac agccttattt caggctgttg ataattctac tatattcttc
     1741 ttgatttgaa aaagaaataa tgatttttcc actgtctttt ttagatagtt taatttctac
     1801 atctaatccg agtagttttc ttaactgttt ttcttcattt tgtatgaaat gattagtttt
     1861 ttgctgtttc ttttgttttt tctctgtcag aagagtttct aacttcctta cagaaatatc
     1921 ttcttctata atccgttgaa agaaatagtc ttgttgtttc ttatttaacc caactaggga
     1981 acgcgcatgg gcttgtgata gtttgccatt ttctacttct gagagaatct gttctggcaa
     2041 ggaaagtaaa cgaatggagt tgctgatata tggacgagac ttgcccatct tatctgcaat
     2101 ttcagcatgg gtgaatcctt tctctacgag agattcatag gcgcgtgctt cttctattgg
     2161 gtttaaattt tctctctgta aattttcaat aatggactgg accatcatct cttggtctga
     2221 aatctgttta acaacagctg ggatagaccg tagaccagct aaaagtgaag cccgatagcg
     2281 tctctctcct gcaaggattt cataaccaat aacaggagat tgacgaacaa taatcggttg
     2341 aatgacccca ttttctttga tagactgtgc tagttcatct agtttttctc tatcaaattc
     2401 ttttcggggt tgatagggat ttttttgtat atctgtgata gaaatcattt caaatttttc
     2461 catgattcta cactaacaca tcttttctct tatgtaaagc tttctttaca tagatgtcaa
     2521 tcaagattct aaatcacctg aactcttgtt aagtttgata gaggtagttt cttctttccc
     2581 gttacgatag taggttatct taatggtgtc tccgatagaa tggttgtaaa gagcactttg
     2641 taagtctgtt gatgaagcaa tctctttgtc atctactttt gtaattacat cgtatttttc
     2701 aaggtgacca ttggcaggca tattactttg taccgaacga acaactacac cagatgtaac
     2761 attacttgga atattgagtc ttctgatgtc gcttgtactc acattagata aattaaccat
     2821 ctggattccc aaagctggac gcgtcacttt tccgtttttt tctaactgtt caataatatt
     2881 gatagcatca tttgcaggaa ttgcgaaacc aagaccttct acagatgttc ctccatttgt
     2941 agcaatttta cttgaggtaa ttccgataac ctgcccttga atattgatca gtgggccgcc
     3001 agagttacct gggttaatag cagtatcagt ttggatggct tttgtagaaa tagcttgtcc
     3061 atcttccgat cttaaggata catttctatt gagactggat acgatacctt gagtgacagt
     3121 atttgcatat tcagaaccta acgggctacc gatggcaata gcagtttctc ctacagttaa
     3181 cttactagaa tcaccaaact cagctactgt tgtcactttt tctgaagaga ttttgacgac
     3241 agcaatatca gagaaagtgt cagctccgac aatttctcca ggtactttag tcccatctga
     3301 caatcgaata tctactttgc tggcgccatt tataacgtga ttgttggtga cgatgtaagc
     3361 ttctttatca ttctttttat aaataactcc agatccttca ctagagattc gctgagaatc
     3421 tgtgtcagta tcatcattgc caaatacgct attttgtctg tttgccgaat aagtaataac
     3481 agaaacaaca gcatctttta ctttgttaac agcctgtgtt gttgaatttt cgttcttata
     3541 ggcagtttgt gtaatagtac tattgttgtt agagttgttt acactacttt tttgagttag
     3601 ttgagttatt gaaaaactac ccaaggctcc actaaaaaag ctaatgacga taacgactaa
     3661 taattgaaac cattttttgt aaaatgtttt tagatgtttc atatttgcct ccatatgttt
     3721 gaattactga aagtataaac tgactagctt aattataact taaacacaaa aattttacac
     3781 aaactgtgga taactctttt gaaactgtga ttttcttaat tgaaatctat tttttatttt
     3841 gtgaataaga tgtgaaaaaa tagagaatat gttagaatag agtcatgaaa attaaagttg
     3901 taacagttgg gaaactgaaa gaaaagtatt taaaagatgg tatcgcagag tattcaaaac
     3961 gaatttctag atttgctaag tttgaaatga ttgagttatc agatgaaaaa acaccagata
     4021 aggccagtga atcagaaaat caaaagattt tagaaataga aggtcagaga attttatcaa
     4081 aaattgctga ccgtgatttc gttattgtgt tagccattga agggaaaact ttcttctcag
     4141 aagaatttag taagcagtta gaagaaactt ctataaaagg attttctact cttactttta
     4201 ttattggggg aagtttagga ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca
     4261 gttttggtcg cctaacctta ccccatcagt taatgagact agttcttgtt gaacaaatct
     4321 atcgcgcttt tacgattcag cagggattcc cctaccataa atagaaaatt gacttttaat
     4381 tgaatttttg gtagaataat tgtattaggt ctcatagctc agctggatag agcattcgcc
     4441 ttctaagcga acggtcgcag gttcgaatcc tgctgggatc aatataatag caaagctggg
     4501 aattttcccg gcttttttct taaaaaagta cactttggga gaaaaaaatg atagttgaga
     4561 gaattttatc taaaacgaaa ttccattttg tataatggtt tttgtaagtt agcttacaag
     4621 aaaaaacatt ttaggagatt ttattatgaa aaacacagtt aaattggaac agtttgtagc
     4681 tttgaaggaa aaagacttac aaaagattaa aggtggggag atgaggttgt caaaattctt
     4741 ccgtgatttt attttacaaa gaaaaaagta atgaaataag gggaaagagt aatggattta
     4801 tttggatttg ggacggttat tgttcatttt ttaattatta gtcacagtta ccattttatt
     4861 tgtaaaggtc aaataaatag aaaagaatta ttcgtttttg gtgcttatac attactaaca
     4921 gaaatagtat ttgattttcc cttatatatt ctatatttag atgggttagg gattgaaaga
     4981 tttttatttc ctttgggatt atattcctat tttcgatgga tgaaacagta tgagagggat
     5041 agaggactat tcctaagttt actactatct cttttatatg agagcactca taactttctg
     5101 tccgtaactt tctcctctat aacaggagat aattttgttt tacaatatca tttcccattc
     5161 tttttcgttg tgacggtgtt aacctatttt gttacattaa aaatcattta ctatttccat
     5221 ttggaactag cctattttga cgaggactac ctttatcctt tcttgaaaaa agtatttttt
     5281 gctttactat tgctacatat tgtatctttc gtttcagata tggtaagtac gattaaacat
     5341 ttgaatagtt ttggaagtat tttgtcatct attgtcttta tctctctcct tttgaccttc
     5401 tttgcaatga attctcataa agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa
     5461 tttgaacaga aacatttaca gaattacaca gatgaaattg ttggtctgta taatgaaatc
     5521 cgtggttttc gacatgatta tgctggaatg cttgtcagca tgcagatggc aattgacagt
     5581 ggtaatttac aggaaattga cagaatttac aatgaagttt tagtcaaagc aaatcataaa
     5641 ttgcgttcag ataagtacac ttactttgat ttgaacaaca tagaagactc agctttacga
     5701 agtttggttg ctcagtcaat tgtctatgct cgaaataatg gtgtagagtt tacactggaa
     5761 gtaaaagata cgattaccaa gcttccaatt gaactattgg atttggttcg tatcatgagc
     5821 gttttattga ataatgctgt cgaaggatcg gctgatagct ataaaaagca gatggaagta
     5881 gcagttatta agatggaaac tgaaacagtt attgtgattc agaattcatg taaaatgacg
     5941 atgactcctt caggagatct atttgcctta ggattctcca ctaagggaag aaatcgcgga
     6001 gtcggattaa ataatgtgaa agaactacta gataagtaca acaatattat tttagaaaca
     6061 gagatggaag gcagtacatt tagacaaatc attagattta agagggaatt tgaatgaaag
     6121 ttttaatttt agaagatgtt attgaacatc aagtgagact agagagaata ttggatgaaa
     6181 tttcgaaaga atcgaatatt ccaatatcat acaagacaac gggaaaagtc cgtgaatttg
     6241 aagaatacat tgaaaatgat gaagtaaatc agctttattt cctagatatc gatattcatg
     6301 gaattgagaa aaagggattt gaagtggctc agctcattcg tcattacaat ccttacgcta
     6361 ttatcgtctt tatcactagt cgatcagagt ttgcgactct aacctataaa taccaggtat
     6421 cagccctaga ttttgttgat aaggatatca atgatgagat gtttaagaag agaattgagc
     6481 aaaatatctt ctacacgaag agtatgttac ttgaaaatga agatgttgta gattatttcg
     6541 actacaatta caagggaaat gatttaaaaa ttccttacca tgatattttg tatattgaaa
     6601 caacaggggt ctctcataaa ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg
     6661 gtaccatgac agatattcag gaaaaggaca aacatactca gcgattttat tctcctcaca
     6721 agtcattttt ggtaaatata ggcaatatca gagaaattga tcgaaaaaac ttagaaattg
     6781 ttttctatga agaccatcgt tgtcctattt caagattaaa aattagaaaa ttaaaagata
     6841 ttttagagaa aaaatctcaa aagtgattga caattagcaa gaaattgata taatggttat
     6901 atctgctaca gatagaaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
     6961 taacacgggt tcgaatcccg tacggactat tttatccgcc atagctcagt tggtagtagc
     7021 gcatgactgt taatcatgat gtcgtaggtt cgagtcctac tggcggagta tagataaaag
     7081 ggaacacagc tgtgttcctc tttttgtatc aatttgtatc accaagcatt ttcataagga
     7141 agtctgttat ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt tggcagacac
     7201 caaaaagtgc atgagttaga tagatgctac tatattctaa ttcggtggta tttagattca
     7261 gttgcataaa tcgcttttgt aaatctgtac taagcatgat atgaagttta tttcgtaaga
     7321 aattttggat ttctttagtc ccattttcag aaagaagggc agccagaagt ggttctgact
     7381 ctagatattc aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa
     7441 tatattcaaa tgtatggaat agcttgcttt gatagtgctc aatcatatca tacttatcct
     7501 tatagtgagt atagaagctg gaacgactaa ttccggcttt ttctactaat ttgacagtag
     7561 aaattttatc aaatggctgt tccatcagta attgtaccat agcattttca atagttcgct
     7621 ttgtttttaa gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa attagactat
     7681 atgtctaaaa atagattttt tatcttgtaa tttagatttt ttaatgtata atctattata
     7741 tcaaaatttt agacaatatg tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa
     7801 tttaaaaaaa acaaccttta ttattgtcat gatcgggatt tctcttattc cagctctgta
     7861 caatatcata tttttgtcat taatgtggga tccatatggg caattgtctg acttacctgt
     7921 ggcagttgta aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa
     7981 agacatggtg tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga
     8041 ggaaggaaag aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga
     8101 tttatctaaa aaaacaacta cattatccaa tattcaatcg acagcagctt atcaatcatt
     8161 gacaagtgag caacaaactg ggataagtga ttctgtatct caaaattcaa ctgatagtat
     8221 tcaatcggct cagtcaattg tagctttagt acaaggttta cagggaagtt tagaaaactt
     8281 acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat
     8341 tacttctact tctttgatag gattgtcaag tggattaaca gagatacaag gagctgttac
     8401 tagcaaatta gttcctgcca gtcagttgat tgcatcaggt gtaaacgcat atactacagg
     8461 tgttgataaa gtttctcagg gcgcaagtca actaagtgaa aaaaatgcca ccttgacaca
     8521 aaaatcttct agattgacag caggagttga taaattacaa tcaggatctg ggcaattagc
     8581 agacaaatcc agtcagttac tttcaggtgc ttcttcatta gagaatggag ctaataaatt
     8641 ggcagatgga tctgggaaac tagcagaagg tggaacaaag ttaacttctg gattggaaga
     8701 tttacagaca ggacttgctt ctttaggaca aggactaggt aatgctagtg atcaactcaa
     8761 atcagtatca acagaatcta aaaatgcaga gattttgtca aatccactca atctttcaaa
     8821 aacagacaat gatcaagttc ctgtaaatgg aatcgcaata gctccttata tgatatcagt
     8881 tgctcttttt gttgcagcaa tatcaacaaa tatgatattt gcgaaattgc cttcaggacg
     8941 tcatccagag agccgttggc cttggttgaa atctcgagct gaaataaatg gtattatagc
     9001 tgttttggca ggaattttgg tatatggagg agttcagctt attggtttaa ctgctaatca
     9061 tgagatgaga atatttattc tcatcatcca aacaagttta gtattcatgt ctatggtgac
     9121 cactttagca acgtggaata gccgtatagg agcttttttc tcacttattt tgcttttact
     9181 atagttagca tcaagtgcag gtacttatcc acttgctttg acaaatgatt tctttagatc
     9241 tattaatccc tggttaccaa tgagctattc agtttcggga ttacgacaaa caatctctat
     9301 caacaagtca ttttcctagc tgtcatacta gctctattta ctggtttagg tatgctagcc
     9361 tatcaacata agaaaatgga agaagattaa aaaaatcgac cgattaactg gtcgattttt
     9421 tatgccttag atgactttcg tctgtgatta tagattccaa atagtaagag agaagtaaag
     9481 gaacagattg ctccagtaat aaaaccattg ggaatgaagg aaagtgtaat agttcctttc
     9541 cccttgggaa tgtcaacttt cataaatcca gtttgagctt gtttaatttc tattttctta
     9601 ccatcttggt aggcagacca acctttgtca taaggaatgg tgaagaaaat agatgtatct
     9661 tgttggacat catatgtagc aaaaaccttg tttttagaag ttgatactgt gacaggttgt
     9721 tctttaattt tttgaattac ctcggtgaaa gttttggtat ctaaacgata gaaggtagga
     9781 gattcaaatg atacttgtga atttccaggg aaactaacat tgatattgaa agtttttttc
     9841 tctttagtat atcctagatt aaagaaggag aagacattat cagttgtaaa agtctttttt
     9901 tcaccattta caaggatgtc aaccttcttt tgtttatcgt tagaaaagtg aaggtttatg
     9961 aaagagagat aaacttggct gttttctgga acttcaattt gatactggat tgctgcatct
    10021 tcatttgaag aacttgtgac actaatcaaa tcattagtat tttctatttt ttctgttttt
    10081 tcataaggta ttggagaaaa ataatcaaaa ttgacgttag caagttgatt taaaaatgag
    10141 gcctgattat ccaaggtatg ttcattgaac ttgacatcat tgtaaacaga ttgactagca
    10201 actgcaatcg gaagagagta ttgattttca tatagggtaa gattatcttt ttgatagata
    10261 tctttaaagc catacttatc aataggactg tctgagatat tgtactggat accaaataaa
    10321 ctatcagcca aaatactatt atttgcatat cggagattga gattagtccc agaggattta
    10381 aaaccaagtt tatctaaagt agagcttgat gaacgatttc gaacagatga aaattgagag
    10441 attccattgt agttgaattt catactgtca tttcctgtct gagtttgtag tttttcagta
    10501 cgagtaaatt gatttccaat atatgttgag aaagattcca tagctgggat atctcgacta
    10561 taagcacttc gagaagcaaa tccccattcc ttagcaattc cgtccatttg agatgaagca
    10621 tttaaactca tttcaaccag tataaataaa gagattagaa tggcaaatag attcacagat
    10681 ataaactttt tgataactgc aaggagtaaa agagaataga caaccaaaaa ttcaagagta
    10741 agcagaatat tcaaatctgt taaaaaagaa taatgcgatt ttagatagat ggtagctaaa
    10801 aatcctgcta ctacaagaaa aagcgaaact aaaaaattcc agactttaag ttctttcaga
    10861 cgctttaaga cttctgctgc tgtgtaaatt aacaaggtag agaaaatcca agcatagcga
    10921 tgtaaaaaca tgtttggagt atgcatgcct tgccaaaata agtcaagagc ttctatgtaa
    10981 aagcttgcaa ttagaaatgc aaagaatatt acatatatga gtttcacgtg aaacttaata
    11041 gatttcagcg taaaaaataa aatggtcaaa ataaagggaa atagtccaac aaaaatcatt
    11101 gggatggccc catactttgt tgtgtcaaag gaaccaatga attgcttagc aaagagatca
    11161 agataccagc tactttcagt ttgaaacttt gtaacttcag tcaatttttc cccatgtgtc
    11221 tgtaaatcaa atagagtggg aagagtcata atcaaactag ccataccagc taaaaaggag
    11281 ataactatga aatcaagaac agatgatttt cgagtcttaa agtcccacga aatttgacag
    11341 agataccaga aaataagaaa caatactgtc atatatccaa aataataatt ttgaataaat
    11401 aagattgaca gacttgtaaa gtacaatagg agtttctttt cagttatcag tagatgtaaa
    11461 ccagttataa ttaaaggaat caagataaaa acatctagcc aggtttttat ctctaattga
    11521 ctgacagtga aactcatcag agcataggaa gtagataagg ctagttttaa agtctgaggg
    11581 atagattgaa acaatttatt caaactaaaa aaggttgaca gaccaatcaa tccaaatttt
    11641 aagagagttg tcagatagat agcatctggc atattcgtta gatcaaaaaa gtaaaccaga
    11701 ggcgcgagaa aactacccaa gtaataacta gatagggcat agaagtttag ccctagacca
    11761 cttgtaaagg tgtaaaacag actactattt ccatgtagga tatttcgtaa ggctacatca
    11821 aaaataacgt attgatgaaa gccatctcct aatagaggag agttgtcgct attccagtag
    11881 ataccttgag atagatatac tccagacata atcactacag gaatgatgaa agaaataaaa
    11941 taggttcgat atgtttttaa aaatgatttc atgttacctc gtagaatgat agaaaactca
    12001 gttggttaac ccaactgagt tttgaagttt tatttagtct ttccaaagtt ctttaacttt
    12061 tgcttgtact tctgcatttt ctaggaattc atcgtaggtt tcatcgatac ggtcaatgac
    12121 gccattttta gataagacaa tgatatggtt agccaaagtt tgaataaatt cgtggtcatg
    12181 gctggcaaag atgattgatt ctttaaagtt tttcaatcca tcattcaagc ttgagataga
    12241 ttccaagtcc aagtgatttg ttggatcatc aagtacaagg acatttgatt ttaagagcat
    12301 gagttttgaa agcatgacac gaactttttc tccccctgac aagacattta caggtttgtt
    12361 aacttcatct ccagagaaga gcatacggcc gaggaagcca cgtaggaaag tattgtcatc
    12421 ttcttcttta cttgcgaatt gacgcaacca gtcaagaatt gattctcctc ctgcaaaatc
    12481 agctgagtta tcttttggta ggtaagattg actagttgta actccccact tgacagttcc
    12541 ttcatagtca atatctccca tgattgcacg aattaatgca gtcgtttgaa tatcattttg
    12601 tccaataagt gctgttttat catctggacg caagatgaaa ctaatattat ccaagatagt
    12661 ttcaccatca atctttacag ttagattttc tactgtcaag agatcattac caatctcacg
    12721 ttccgcttta aagttgataa atggatattt acgactagat ggcacaatct cttctagctc
    12781 aatcttatca agcattttct tacgtgatgt tgcctgcctt gacttagaag cattggcaga
    12841 gaaacgagca acaaattctt gcaattgttt aattttttct tctgctttag cattacggtc
    12901 tgctagcaat ttagcagcaa gctcagaaga ttccttccag aagtcgtagt ttccgacata
    12961 gagtttgatt tttccaaagt caaggtcggc catgtgagta caaactttgt ttaagaagtg
    13021 acggtcgtgg gatactacga taactgtgtt atcaaagtca attaagaagt cttctaacca
    13081 agtaatcgat tggatatcca aaccgttagt aggctcgtcc aagagaagaa catctggttt
    13141 accaaaaagt gctttggcga ggagaacctt tactttttca ccgttggcca attcgctcat
    13201 gttttggtag tgtaattctt ctggaatgtt taggttttga agtagttgag aggcttcact
    13261 ctctgcttcc caacctccaa gttcggcaaa ctctccttcg agttcggcag cacgaacccc
    13321 gtcctcgtct gagaaatctt ccttcatgta gatagcatct ttctctttca tgatgctata
    13381 aagtttttca tttcccatga taacgacatc aatggcacgt tcatcttcgt agtcaaagtg
    13441 attttgacga agaacagaga gacgttcatc tggaccaaga gagatgtgac cagtagtagg
    13501 ttcgatatct ccagctaaaa tttttaaaaa ggttgatttt ccggcaccat tagcaccgat
    13561 taatccgtaa gtatttcctt ctgtaaattt gatattgaca tcatcaaaaa gtttgcgatc
    13621 actaaaacgt agtgaaacat cagatactgt aagcaatatt tttctcctat atgtgtaata
    13681 tatttattct actagaaaat acagaaatat tcaaattttt atttgtcaat tttgtgtaaa
    13741 ttatatttac agtatccttt acacaaatct gtaaaaagca aggctgattt attttgataa
    13801 attacggtta tttcattaaa aaaatgctat aattgaaagg actatatcga aggagaacaa
    13861 aatgactaaa cccattattt taacaggaga ccgtccaaca ggaaaattgc atattggaca
    13921 ttatgttgga agtctcaaaa atcgagtatt attacaggaa gaggataagt atgatatgtt
    13981 tgtgttcttg gctgaccaac aagccttgac agatcatgcc aaagatcctc aaaccattgt
    14041 agagtctatc ggaaatgtgg ctttggatta tcttgcagtt ggattggatc caaataagtc
    14101 aactattttt attcaaagcc agattccaga gttggctgag ttgtctatgt attatatgaa
    14161 tctagtttcg ttagcacgtt tggagcgaaa tccaacagtc aagacagaga tttctcagaa
    14221 aggatttgga gaaagcattc cgacaggatt cttggtctat ccaatcgctc aagcagctga
    14281 tatcacagct ttcaaggcta attatgttcc tgttgggaca gatcagaaac caatgattga
    14341 gcaaactcgt gaaattgttc gttcttttaa caatgcatat aactgtgatg tcttggtaga
    14401 gccggaaggt atttatccag aaaatgagag agcagggcgt ttgcctggtt tagatggaaa
    14461 tgctaaaatg tctaaatcac taaataatgg tatttattta gctgatgatg cggatacttt
    14521 gcgtaaaaaa gtaatgagta tgtatacaga tccagatcat atccgcgttg aggatccagg
    14581 taagattgag ggaaatatgg ttttccatta tctagatgtt tttggtcgtc cagaagatgc
    14641 tcaagaaatt gctgatatga aagaacgtta tcaacgaggt ggtcttggtg atgtgaagac
    14701 caagcgttat ctacttgaaa tattagaacg tgaactgggt cctattcgtg agcgccgtat
    14761 tgaatttgct aaggatatgg gagaagttta taatatgatt caaaaaggta gtgaaagagc
    14821 gcgtgaagtt gcgggtcaaa ccctatctga ggtaaaaggg gcaatgggac ttcattactt
    14881 taactaagtt tattttacaa gaaactatca tttctatctc gaagaaaaga tagtttttta
    14941 tttacccctg taacatttga caaattttta tagaatggta tgatagatac aatataaaaa
    15001 gagtcaagct caaaaagaaa gaaaagagga aacttcgaat gtctaattgg gacactaaat
    15061 ttttgaaaaa aggttttacc tttgatgatg tattgcttat tccagctgaa agtcatgtgt
    15121 tgcctaacga tgcagattta acaactaaat tggcagataa tttgacttta aatatcccaa
    15181 ttattaccgc tgccatggac acagttacag agagtcaaat ggccattgct attgctcgtg
    15241 caggtggtct cggagttatc cataaaaaca tgtcaattgc tcaacaagca gacgaggttc
    15301 gtaaggtaaa acgttctgaa aatggagtta ttattgatcc gttcttcttg acgcctgaac
    15361 atacaattgc tgaagcagat gagcttatgg gtcgttaccg catcagtggt gttccagttg
    15421 ttgaaacact tgaaaatcgt aaattggttg gtattttgac aaaccgagat cttcgtttta
    15481 tttcagatta taatcaacca atttcaaacc atatgactag tgaaaatctt gttactgctc
    15541 ctgtgggtac ggatcttgca acggctgaga gtattcttca agagcatcgt attgaaaaac
    15601 ttccgttggt tgatgaagaa ggcagtcttt ctggtttgat cactatcaaa gatattgaaa
    15661 aagttattga gtttccaaat gcggctaaag atgagtttgg tcgtcttcta gttgcaggtg
    15721 cagtaggtgt tacttcagat acatttgaac gtgcagaggc tctttttgag gcaggagcgg
    15781 atgcgattgt tattgatact gcacatggtc attctgcagg tgtcttgcgt aaaattgccg
    15841 agattcgtgc tcatttccca gatcggactt tgattgctgg aaatattgct actgctgaag
    15901 gtgcacgtgc cctttatgaa gcgggtgtag acgttgttaa ggttggtatt ggaccaggtt
    15961 ctatctgtac tactcgtgtg attgctggtg ttggtgttcc gcaagtaaca gctatctacg
    16021 atgctgcagc tgttgcgcgc gaatatggta aaacgattat tgctgacggt gggatcaagt
    16081 attctggaga tattgtaaaa gcacttgctg caggtggaaa tgctgttatg cttggatcta
    16141 tgtttgctgg aactgatgaa gctccaggcg aaactgaaat cttccaagga cgtaaattca
    16201 agacttaccg tggtatggga tcaattgctg ctatgaagaa aggttcaagc gaccgttatt
    16261 tccaaggttc tgtcaatgaa gcaaacaagc ttgttccaga aggaattgaa ggtcgtgttg
    16321 cttataaagg agcggcagct gatattgttt tccaaatgat tggtggtatt cgctctggta
    16381 tgggttactg tggtgcagct aaccttaaag aactacacga taatgctcaa tttattgaaa
    16441 tgtctggtgc tggtttgaaa gaaagccatc ctcatgatgt gcaaattact aatgaggcac
    16501 caaattattc tatgtaaaaa acaatgaaaa gaactccagt gaaaacagga gttcttttac
    16561 aatgttgtca atttccattt acagcagctt taccatcctg aatagtgaag atacttagat
    16621 tttctggcag attttgaaga tggtctaagc ttgttgttgt gataaaggtt tggattgatt
    16681 gagaaatcgt ttctaataat tttaactgtc tagtgttgtc aagttcactc atcacatcgt
    16741 caagcagtaa tataggagat tctgtggtaa tgctttccat taattcgatt tctgctaatt
    16801 ttatcgagag gacgagacta cgatgttgac cttggcttcc gaaactagca tccatcccat
    16861 ttatataaaa agaaatgtca tctcgatgag gaccgacacc agtattcttt ttaaataaat
    16921 ctctggatct acttttttct aaagcaattt tgaaagattc ggataagttt tgtttgtcag
    16981 ttatattgac agaagattga taggatattg acaactcttc gatctgatta gagagttcaa
    17041 aatgtttctt acgcccaaat gattctagtt tttttatgaa atctaagcgg tgattcatta
    17101 cacgacatcc ataatcaact agctgatcat ctaacacaga aaggaatgtt tcatctattt
    17161 tttgagctga ttttaggtaa gtgtttcttt gctttaggat gtggttataa ttggttaagt
    17221 cagataaata gattggctta atttgcccaa gttccatatc aatgaatttt cgtcgaatcg
    17281 aaggtgctcc tttaattagt tgtaaatctt caggagcaaa taagacaaca ttcatgtgtc
    17341 ctacataatc tgaaaggcgt gcctgtttta agtgattaac ttttgttaca cggccttttt
    17401 gtgttagttc gatttctagg ggaatggatc cagttttttt ctgaacgaga cctgaaagat
    17461 gaagttgttc ctcatcaaaa tgaatgagat ttttatctgt tcgagttcga tgactacgcg
    17521 ttaaggctaa aaaatagata gcctctaaca tgtttgtttt tccttgtgca ttacgtccca
    17581 aaaagacatt caatttagga ttaaagtcta ttttcgtttc tttgtaatta cgaaaagtct
    17641 tgagagatag atgttgtagc cacatgatta tctaccaggg aatcgtggag cttgttggct
    17701 tttaggtgat gaagcaggtt tcgatttgtc ttttttaact cccttattca tctttttgac
    17761 aagtttagcg atccgttctt tttcaacttt atcagcttgg tattcatctt gttcttcaga
    17821 agtaggttgt gtcaacaaga tgtcaatgtt catgtcaggg atgtcaactt tatcgccaat
    17881 acgaagtttt tttccacgac gactctctaa ttccctatta aagtaaacag aatgttcaga
    17941 gagaaatgat ttaatagctc ctccgctatg tgtaattcca agttctttga gtagtgcttg
    18001 gagggtaata aattcttcaa ataatttgta ttccataatt cacctcaatc tttggtatta
    18061 taccatattt tcctaaaaat agtgagagag acagcgagaa atgtaagcga tttttatttc
    18121 aaaagtgtta cagggaacaa gaaaatttca ggttttcgtg atataataga agtctgtata
    18181 taaggaggta aatcatggag ttagtgcatg gaatttcaac acattttatc caatcaaaaa
    18241 agtttaaaac aaacaaaatt accgtgcgtt ttaccgctcc attatccctt gatacgattg
    18301 caggtcacat gttgagtgca agtatgctag agactgctaa tcagatgtac cccacttctc
    18361 aagatttgag gagacacttg gccagtctat acggtacaga tatgtcaacc aattgtttca
    18421 gaagagggca aagccacatt atagaattga catttaccta tgttcgtgat gagtttttaa
    18481 gtaggaaaaa cgtgctaacc tctcagattt tggaacttgt aaaagaaact cttttttcac
    18541 ccgtagtagt tgataatggg tttgatccgg ccttatttga aattgagaaa aaacaattgc
    18601 tagcaagttt agcagctgat atggatgatt ctttttattt tgcacataaa gaattggata
    18661 aattgttttt tcatgatgaa cgtcttcaat tggaatatag tgatttacga aatcgtattt
    18721 tagctgaaac tccacaaagt tcttattctt gtttccaaga atttttagcc aatgatcgaa
    18781 tagatttctt tttcctaggt gattttaatg aggttgaaat tcaaaatgta ttagaatcat
    18841 ttggctttaa aggtcgaaaa ggagatgtga aggttcagta ttgtcaacct tattctaata
    18901 tccttcagga aggtatggtt cggaaaaatg tgggacaatc tattttggaa ttaggttatc
    18961 attacccttc taaatatggt gatgagcaac atttacccat gattgtaatg aatggtttac
    19021 ttggtggatt tgctcactct aagctcttta caaatgtccg tgaaaatgct ggattagctt
    19081 ataccatttc aagtgagctt gatttattta gtggattctt gaggatgtat gctggtatca
    19141 atcgagaaaa tcgtaaccag gctcgtaaaa tgatgaataa tcaactgctt gatttaaaaa
    19201 aaggttattt tacagagttt gagttaaatc agaccaagga aatgattcgt tggtcgttgt
    19261 tactttctca agataatcaa tcttcattga ttgaacgtgc ttatcaaaat gccttatttg
    19321 gaaaatcttc agcagacttt aaaagttgga ttgcaaagct tgaacagatt gacaaagatg
    19381 ctatttgtag agtagctaat aatgtgaaac tacaagcgat ttactttatg gaaggaatag
    19441 aatgacaaag gttgtttttg aagaaaaata ctatccagct gtaaaagaaa aggtttatcg
    19501 aactcgtttg gccaacggat tgacagttgc tcttttgcct aaaaaggaat ttaaagaggt
    19561 ttacgggagt gtaactgtac agtttggttc gatagatacg cttgtcacag aagttgacgg
    19621 agatgtaaaa caatatcctg gaggaattgc tcattttctt gaacataaat tatttgagag
    19681 agaagattct agtgatttga tgtcggcttt tacgagtcta ggtgcagata gtaatgcctt
    19741 tacaagcttt acaaaaacaa actatctttt ttcagcaacg gattattttt tagaaaattt
    19801 atatttactt gatgaattgg taacatcagc acactttact gaagcttcca ttctgacaga
    19861 gcaggatatt attcagcaag aacgagaaat gtaccaagat gatccagatt cgtgtttatt
    19921 cttttcaact ttagcgaatt tgtatcctgg tacaccttta gcaactgata tagttggaag
    19981 tgaggagtcc atttcccaaa tcaatttaac taatttgcaa gaaaatttta caaagtttta
    20041 caaacctgta aacatgtctc tgtttttagt tggtaatttt gatgtggagc gagtacagga
    20101 ctattttgaa agcaaagaac tgaaagattc agattttcag gaagtagcaa gagaaaagtt
    20161 gtttttacag cctgtaaagc caacagatag tatgagaatg gaagtatctt ctcccaaact
    20221 agcgattgga gttagaggta agcgagaagt ttctgaagcg gattgctatc gacatcatat
    20281 tttattaaaa ttattgtttg caatgatgtt tggttggact tcggatcgtt ttcaaaaatg
    20341 ttatgaatca ggtaaaattg atgcgtcctt atctctggaa gttgaaataa caagtcgctt
    20401 tcattttgtc atgttgacaa tggatacgaa agagccagtt gctttgtctc atcaatttag
    20461 gaaggctatt cgtaatttta caaaggattt agatattaca gaggaacatt tagatattat
    20521 caaaagagag atgtttggcg aatttttcag tagcatgaac tctcttgaat ttattgcaac
    20581 gcaatatgat gcttttgaaa atggtgagac aatttttgat ttgccgaaaa ttttacagga
    20641 aattacttta gaggatgtcc ttgatgctgg acatcattta atagatgatg gtgacatagt
    20701 tgattttaca atattcccat cgtagtaacc tatcataata gacactagaa agaagggatg
    20761 acaagtatga gaaaaaaaac aattggagag gttttacgat tagctagaat caatcaggga
    20821 ttgagtttag atgaattgca gaaaaagaca gaaatccagt tagatatgtt ggaagcaatg
    20881 gaagcagacg atttcgatca acttccaagt cctttttaca cgcgttcttt cttgaaaaaa
    20941 tatgcatggg ctgttgagtt agatgaccaa attgttttgg atgcttatga ttctgggagt
    21001 atgattactt atgaggaagt agatgttgat gaagatgagt tgacaggtcg tagacgttca
    21061 agtaagaaaa agaagaaaaa aacatcattt ttacctttat tttattttat cctttttgct
    21121 ttatcgattt taatttttgt gacttattat gtttggaact atattcaaac tcaaccagag
    21181 gagccttctc tttctaatta cagtgtggtt caatcaacaa gttcaactag ctctgttccc
    21241 cactcctcaa gtagtagttc ttctagtata gaatcagcta taagtgtatc aggcgaagga
    21301 aatcatgtag aaatcgctta taagacaagt aaggaaacag ttaaattgca attggcagtt
    21361 tcagatgtta caagttgggt cagtgtttca gaaagcgaac ttgagggcgg tgtaacctta
    21421 tcgccaaaga agaaaagtgc agaagcaaca gttgcaacta aaagtcctgt aacaattacg
    21481 ttaggtgttg taaaaggtgt tgatttgaca gtagataatc agactgttga tttatcgaaa
    21541 ttaacagctc agactggaca aatcactgta acctttacta aaaattaagg aaaaacgaat
    21601 gaaaaaagaa caaattccca atctcttaac aataggtcga attctcttta tacctatttt
    21661 tatctttatt ttaacgatag gaaattcgat agagagtcat atagttgcag ctattatctt
    21721 tgctgttgcc agtattaccg actatttaga tggatattta gctcgtaaat ggaatgtggt
    21781 cagtaatttt ggtaaatttg cagatcctat ggcagataag ttactagtta tgtcggcttt
    21841 tattatgttg attgagttag gtatggctcc ggcttggatt gttgcagtga ttatctgtcg
    21901 tgagttagct gtgacaggtt taaggctttt attggttgaa actggtggaa caattttagc
    21961 agcagcaatg cctggaaaaa ttaaaacttt tagtcagatg tttgctatta ttttcttgct
    22021 attacattgg actttgcttg gtcaagttct actttatgta gccttatttt tcactatcta
    22081 ctctggctat gactatttca agggtagtgc ctatgtattt aaagggacat ttggttcgaa
    22141 atgaaatcaa taattgatgt aaaaaatctt tcttttcgct ataaagaaaa tcagaactac
    22201 tacgatgtga aggatattac gtttcacgtg aaacgtggag aatggctttc gattgtaggg
    22261 cataatggta gtggtaaatc aacgacggtt cgattaattg atggcttact ggaagcagaa
    22321 tccggagaga ttgtaattga tggccaacgt ttgactgagg aaaatgtttg gaatatacgt
    22381 cgtcaaatcg gtatggtttt tcaaaatcca gacaatcaat ttgttggagc gactgttgaa
    22441 gatgatgttg cttttggttt ggaaaatcag ggactttctc gtcaagaaat gaaaaagaga
    22501 gtggaagaag ctctggcttt agttggcatg ttggacttta aaaagagaga gccagcgcgt
    22561 ctatcaggtg gccaaaagca acgtgtggcc attgcaggtg ttgtagccct aagaccagct
    22621 attttaatct tagatgaagc aacgagtatg ttggatcctg aggggcgtag agaacttatt
    22681 gggacagtaa aaggaattcg aaaagactat gatatgacgg tcatttctat tacccatgat
    22741 ttggaagaag tcgccatgag tgatcgcgta ttggtcatga aaaaagggga aattgaatca
    22801 actagtagtc caagggagct tttctctcga aatgatttag atcaaattgg attagacgat
    22861 ccttttgcta atcaattaaa aaaatctttg agccagaatg gctatgattt acctgaaaat
    22921 tatttgacag aaagtgagct agaggataag ctatgggaat tgctctagaa aatgtgaatt
    22981 ttacatatca agaaggtact cccttagctt cagcagcttt gtcggatgtt tctttgacga
    23041 ttgaagatgg ctcttataca gctttaattg ggcacacagg tagtggtaaa tcaactattt
    23101 tacaactctt aaatggttta ttggtgccaa gtcaagggag tgtgagggtt tttgatacct
    23161 taatcacctc gacttctaaa aataaagata ttcgtcaaat tagaaaacag gttggcttgg
    23221 tatttcagtt tgctgaaaat cagatttttg aagaaacggt tttgaaggac gttgcttttg
    23281 gaccgcaaaa ttttggagtt tctgaagaag atgctgtgaa gactgcgcgt gagaaactgg
    23341 ctctggttgg aattgatgaa tcactttttg atcgtagtcc gtttgagctg tcagggggac
    23401 aaatgagacg tgttgccatt gcaggcatac ttgccatgga gccagctata ttagtcttag
    23461 atgagccaac agctggtcta gatcctctag ggagaaaaga gttgatgacc ctgttcaaaa
    23521 aactccacca gtcagggatg accatcgtct tggtaacgca tttgatggat gatgttgctg
    23581 aatatgcaaa tcaagtctat gtaatggaaa agggacgttt agtaaagggg ggcaaaccaa
    23641 gtgatgtctt tcaagacgtt gtttttatgg aagaagttca gttgggagta cctaaaatta
    23701 cggccttttg taaacgattg gctgatagag gcgtgtcatt taaacgatta ccgattaaga
    23761 tagaggagtt caaggagtcg ctaaatggat agtatgattt tggggcgtta tatcccaggg
    23821 gattcgattg ttcaccgatt ggatccacgt agcaaattgc ttgctatgat gctactgatt
    23881 ttgattgtgt tttgggctaa taaccccttg acgaatctga ttctttttat agcgacaggg
    23941 atatttattg ccttgtcagg agtatctctt tcatttttta ttcagggctt gaagtctatg
    24001 tttttcttga ttgccttcac aactattttt caactatttt tcatttctaa tgggaatgtt
    24061 ttatttgagt tttcgtttgt gagaatcacg gattatgctt tgcaacaagc tgggattatt
    24121 ttttgtcgct ttgtattgat tattttcttt tcaactttgt taaccttaac aaccatgcct
    24181 ttaagtttgg catcagctgt cgaagcttta ttagcacctt taaagcgtgt gaaagttcca
    24241 gttcatgaaa ttggattgat gctgtctatg agtttgcgtt ttgtcccaac cttgatggat
    24301 gatacgacgc ggattatgaa tgcacagaaa gctcgtggag tggattttgg agaaggaagt
    24361 atcgttcaaa aagtaaaggc gatgattccc attttgattc ctctttttgc gacaagttta
    24421 aaacgtgcag attccttggc tatcgctatg gaagcgcgtg gctatcaggg tggaaaaggc
    24481 agaagtcaat accgacaatt gaaatggact ctaaaggata cgctgaccat tcttgttatt
    24541 ctcgtacttg gttgttgttt atttttctta aaatcttagt agctttcagg aattgataaa
    24601 aagttactgt aacagttttt gatataaagg tagggatatg aaccgtttta aaaaatcaaa
    24661 atatgtcatt attgtttttg tcactgttct gcttgtgtca gctctcttag cgacgactta
    24721 ttcaagtaca attgtgacaa aattaggaga tggaatctca ttggttgata gagttgtaca
    24781 aaaacctttt cagtggtttg attctgtcaa atcagatttg gctcatttga cacgaacata
    24841 taatgaaaat gaaagtttga agaaacagct ttaccaatta gaagttaaat caaatgaggt
    24901 ggaaagttta aagacagaaa atgaacaact gcgccaattg cttgatatga agtctaaatt
    24961 gcaagccaca aagactttag cagcagatgt tattatgcgt tctccggtat cttggaagca
    25021 ggagttgacc ttagatgcag gtagatcaaa aggtgcttct gagaacatgt tagctattgc
    25081 aaatggtggc ttgattggga gtgtttcaaa agtagaggag aactctacta tagtcaacct
    25141 tctgacaaat acggaaaatg ctgataagat ttctgttaaa attcaacatg gctctactac
    25201 aatttatgga attattattg gctatgacaa ggaaaatgac gttcttaaaa ttagccaatt
    25261 aaatagtaat agcgatatta gtgcgggaga taaggtgact actggtggat taggaaactt
    25321 taacgttgct gatattcctg ttggtgaagt ggttgccaca acgcatagta cagactattt
    25381 gacacgagaa gtaactgtta aattgagtgc agatactcat aatgtagatg tgatagaatt
    25441 agtggggaat tcataatgag acagttgaag cgagttggag tatttttatt gcttcctttc
    25501 tttgttctaa ttgacgccca tattagccag cttctgggct catttttccc ccatgtacat
    25561 ttggctagtc attttctttt tctatttctc ttatttgaga cgatagaagt atcagagtat
    25621 ctctacctag tctattgttt tgttataggc ttggtttatg atgtttactt tttccatcta
    25681 atagggatta caactctctt atttatctta ttgggagcct tccttcataa attgaatagt
    25741 gttattttgt tgaatcgttg gacaagaatg ctagctatga ttgtgctgac attcctgttt
    25801 gaaatgggta gttatctttt ggcttttatg gtagggttga cagtagatag catgtcgatt
    25861 tttatagtct atagcttggt accgacgatg attttaaatt ttttatggat tactgttttt
    25921 caatttattt ttgaaaaata ttatctataa gaacgacata taaatgtaac aaaggcgtaa
    25981 tatttattag gccttttttt ggtatactag tattgtcttt aaaagaagga gtatctacgt
    26041 aatatgaaga aaaaaatctt agcgtcactt ttattaagta cagtaatggt ttctcaagta
    26101 gctgttttaa caactgcgca tgcagaaacg actgatgaca aaattgctgc tcaagataat
    26161 aaaattagta acttaacagc acaacaacaa gaagcccaaa aacaagttga ccaaattcag
    26221 gagcaagtat cagctattca agctgagcag tctaacttgc aagctgaaaa tgatagatta
    26281 caagcagaat ctaagaaact cgagggtgag attacagaac tttctaaaaa cattgtttct
    26341 cgtaaccaat cgttggaaaa acaagctcgt agtgctcaaa caaatggagc cgtaactagc
    26401 tatatcaata ccattgtaaa ctcaaaatca attacagaag ctatttcacg tgttgctgca
    26461 atgagtgaaa tcgtatctgc aaacaacaaa atgttagaac aacaaaaggc agataaaaaa
    26521 gctatttctg aaaaacaagt agcaaataat gatgctatca atactgtaat tgctaatcaa
    26581 caaaaattgg ctgatgatgc tcaagcattg actacgaaac aggcagaact aaaagctgct
    26641 gaattaagtc ttgctgctga gaaagcgaca gctgaagggg aaaaagcaag tctattagag
    26701 caaaaagcag cagctgaggc agaggctcgt gcagctgcgg tagcagaagc agcttataaa
    26761 gaaaaacgag ctagccaaca acaatcagta cttgcttcag caaacactaa cttaacagct
    26821 caagtgcaag cagtatctga atctgcagca gcacctgtcc gtgcaaaagt tcgtccaaca
    26881 tacagtacaa acgcttcaag ttatccaatt ggagaatgta catggggagt aaaaacattg
    26941 gcaccttggg ctggagacta ctggggtaat ggagcacagt gggctacaag tgcagcagca
    27001 gcaggtttcc gtacaggttc aacacctcaa gttggagcaa ttgcatgttg gaatgatggt
    27061 ggatatggtc acgtagcggt tgttacagct gttgaatcaa caacacgtat ccaagtatca
    27121 gaatcaaatt atgcaggtaa tcgtacaatt ggaaatcacc gtggatggtt caatccaaca
    27181 acaacttctg aaggttttgt tacatatatt tatgcagatt aatttacaga gggactcgaa
    27241 tagagccctc ttttcaggtt ttaccgtgac aatccctatt aaaaattata tcaaaatagc
    27301 ttgaaaatat tggaaaagta tggtagaatg aaaattgtcg tgtgaacgat aatactcatt
    27361 cttgatgaat tgtgaagcag ttgcccttgg gtcgttttgc gagttgaagt caagaagagg
    27421 aaaaaaacaa aaaggagaaa tactcatggc agtaatttca atgaaacaac ttcttgaggc
    27481 tggtgtacac tttggtcacc aaactcgtcg ctggaatcct aagatggcta agtacatctt
    27541 tactgaacgt aacggaatcc acgttatcga cttgcaacaa actgtaaaat acgctgacca
    27601 agcatacgac ttcatgcgtg atgcagcagc taacgatgca gttgtattgt tcgttggtac
    27661 taagaaacaa gcagctgatg cagttgctga agaagcagta cgttcaggtc aatacttcat
    27721 caaccaccgt tggttgggtg gaactcttac aaactgggga acaatccaaa aacgtatcgc
    27781 tcgtttgaaa gaaattaaac gtatggaaga agctggaact ttcgaagttc ttcctaagaa
    27841 agaagttgca cttcttaaca aacaacgtgc gcgtcttgaa aaattcttgg gcggtatcga
    27901 agatatgcct cgtatcccag atgtgatgta cgtagttgac ccacataaag agcaaatcgc
    27961 tgttaaagaa gctaaaaaat tgggaatccc agttgtagcg atggttgaca ccaatactga
    28021 tccagatgat atcgatgtaa tcatcccagc taacgatgac gctatccgtg ctgttaaatt
    28081 gatcacagct aaattggctg acgctattat cgaaggacgt caaggtgagg atgcagtagc
    28141 agttgaagca gaatttgcag cttcagaaac tcaagcagat tcaattgaag aaatcgttga
    28201 agttgtagaa ggtgacaacg cttaatttat acaaatagta attacctagg agggcggggc
    28261 ttagcccggc tctcctattt tcaaaaaata taggagaatt aaaatggcag aaattacagc
    28321 taaacttgta aaagagttgc gtgaaaaatc tggtgccggt gttatggacg ctaaaaaagc
    28381 gcttgtagaa acagacggtg acatcgaaaa agcgattgaa ttgcttcgtg aaaaaggtat
    28441 ggctaaggca gctaagaaag ctgaccgtgt tgctgcagaa ggtttgactg gtgtttatgt
    28501 taacggtaat gttgcagcag ttattgaagt aaacgctgaa actgacttcg ttgcaaaaaa
    28561 cgctcaattc gttgaattgg taaatactac agctaaagtc attgctgaag gaaaacctgc
    28621 taacaatgaa gaagctcttg ctttgataat gccttcaggt gaaactcttg aagctgcata
    28681 cgtatctgca acagcaacta tcggagagaa aatctcattc cgtcgctttg cattgattga
    28741 aaaaacagac gcacaacact ttggagcata ccaacataac ggtggacgta tcggtgttat
    28801 ttcagttgtt gaaggtggag acgaagcact tgctaaacaa ttgtcaatgc acatcgcagc
    28861 gatgaaacca acagttcttt cttacaaaga attggatgag caattcgtta aagatgagtt
    28921 ggcacaattg aatcacgtta tcgaccaaga caacgaaagc cgtgcaatgg ttaataaacc
    28981 agctcttcca cacttgaagt atggatcaaa agctcaatta actgatgatg ttattgctca
    29041 agctgaagct gacatcaaag ctgaattggc tgcagaaggc aaaccagaaa aaatctggga
    29101 caaaattatt ccaggtaaaa tggatcgctt catgcttgat aacactaaag ttgaccaagc
    29161 ttacacactt cttgcacaag tttacatcat ggatgacagc aagacagttg aagcatacct
    29221 tgaatcagtt aacgcttcgg tagttgagtt tgctcgcttt gaagttggtg aaggtatcga
    29281 gaaagctgca aacgacttcg aagctgaagt tgcagctaca atggcagcag ccttgaataa
    29341 ctaataatag aaaggaagca aattgcttcc ttttttgtat agggcttaga tttttcctga
    29401 aattgttttt tccccagtct cactcgatta gaataattaa aacaaaaagc cctataataa
    29461 gggctaagtg catttaggag actatacttc aaattcatag taagcgcgtc ata
//
LOCUS       DAVKXA010000024        28341 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKXA010000024 DAVKXA010000000
VERSION     DAVKXA010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.024"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            523..1686
                     /locus_tag="VW883_001132"
     CDS             523..1686
                     /locus_tag="VW883_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0274276.1"
                     /translation="MNRIRVSKRVEKKVAKGLVLLEASDLENVNLKDREVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLNY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASHTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1683..2360
                     /locus_tag="VW883_001133"
     CDS             1683..2360
                     /locus_tag="VW883_001133"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0274277.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2350..3204
                     /locus_tag="VW883_001134"
     CDS             2350..3204
                     /locus_tag="VW883_001134"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0274278.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWIGKEMPTEEIW
                     QSLTEKYQ"
     gene            3223..4290
                     /locus_tag="VW883_001135"
     CDS             3223..4290
                     /locus_tag="VW883_001135"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0274279.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4300..5466
                     /gene="aroC"
                     /locus_tag="VW883_001136"
     CDS             4300..5466
                     /gene="aroC"
                     /locus_tag="VW883_001136"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0274280.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLVELDVEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5476..6579
                     /locus_tag="VW883_001137"
     CDS             5476..6579
                     /locus_tag="VW883_001137"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0274281.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKYLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6590..6928
                     /locus_tag="VW883_001138"
     CDS             6590..6928
                     /locus_tag="VW883_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0274282.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            7020..8303
                     /gene="aroA"
                     /locus_tag="VW883_001139"
     CDS             7020..8303
                     /gene="aroA"
                     /locus_tag="VW883_001139"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0274283.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8296..8772
                     /locus_tag="VW883_001140"
     CDS             8296..8772
                     /locus_tag="VW883_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0274284.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8769..9617
                     /gene="pheA"
                     /locus_tag="VW883_001141"
     CDS             8769..9617
                     /gene="pheA"
                     /locus_tag="VW883_001141"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0274285.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9614..10888
                     /gene="psr"
                     /locus_tag="VW883_001142"
     CDS             9614..10888
                     /gene="psr"
                     /locus_tag="VW883_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0274286.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMDLR"
     gene            11167..12012
                     /locus_tag="VW883_001143"
     CDS             11167..12012
                     /locus_tag="VW883_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0274287.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            12002..13105
                     /locus_tag="VW883_001144"
     CDS             12002..13105
                     /locus_tag="VW883_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0274288.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            13107..14093
                     /locus_tag="VW883_001145"
     CDS             13107..14093
                     /locus_tag="VW883_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0274289.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFKAYS
                     QIHRFLKDHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            14109..15542
                     /locus_tag="VW883_001146"
     CDS             14109..15542
                     /locus_tag="VW883_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0274290.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRIILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMFTKEN"
     gene            15571..16605
                     /locus_tag="VW883_001147"
     CDS             15571..16605
                     /locus_tag="VW883_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0274291.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16805..17542
                     /gene="mecA"
                     /locus_tag="VW883_001148"
     CDS             16805..17542
                     /gene="mecA"
                     /locus_tag="VW883_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0274292.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17693..18979
                     /locus_tag="VW883_001149"
     CDS             17693..18979
                     /locus_tag="VW883_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0274293.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18981..19850
                     /locus_tag="VW883_001150"
     CDS             18981..19850
                     /locus_tag="VW883_001150"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0274294.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            20100..21038
                     /gene="msrB"
                     /locus_tag="VW883_001151"
     CDS             20100..21038
                     /gene="msrB"
                     /locus_tag="VW883_001151"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0274295.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            21096..22820
                     /locus_tag="VW883_001152"
     CDS             21096..22820
                     /locus_tag="VW883_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274296.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKLELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMIQGQILGIIGGTGSGKSSLIQLILGLYPVNKGRIDL
                     YLDGLSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     ILKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHEKED"
     gene            22822..24570
                     /locus_tag="VW883_001153"
     CDS             22822..24570
                     /locus_tag="VW883_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274297.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSLVFWQIFLHMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24872..26131
                     /locus_tag="VW883_001154"
     CDS             24872..26131
                     /locus_tag="VW883_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0274298.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPIGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAEEQVVKQGQVLTVEL"
     misc_feature    26207..26342
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26381..26881
                     /locus_tag="VW883_001155"
     CDS             26381..26881
                     /locus_tag="VW883_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0274299.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26957..27325
                     /gene="rplL"
                     /locus_tag="VW883_001156"
     CDS             26957..27325
                     /gene="rplL"
                     /locus_tag="VW883_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0274300.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27572..>28341
                     /locus_tag="VW883_001157"
     CDS             27572..>28341
                     /locus_tag="VW883_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0274301.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIV"
BASE COUNT         8477 a         5215 c         6335 g         8314 t
ORIGIN      
        1 ttgggatatt tttcaatttc aaaaacgtta attcctataa tgtgtgtgat ccaagtattt
       61 ttgatagaac atatatttag agttcgaaat agaatgatgc aaataggtga aattttaatt
      121 attgttgctt ctataatatt atttattgat agtatattga gtttgtaaca aaaggcttct
      181 ctataaaatc aaattttcca gatacctact gaagctgatt tatttcttca tctttcttct
      241 actacctttg tcactaaatt tgacagacac atattgctga tacaacctct ctacctataa
      301 tctcacggtt aacctgaggc tagtttcata gtttgctatt tgattttcgt tgataaaaag
      361 aaatgctcct ccaagacgga agagcatttt ttattgtgat tcttacacat ttatttccta
      421 gttttgcagg aagtctagta taccattttt taaaagaaga gtaaaaaagc aagggtagtt
      481 tcttttttga gaattgtcta aaagtttgat ataatggcag ttatgaatag aataagagtc
      541 agcaaaaggg ttgaaaagaa ggttgctaag gggctagttt tactagaagc cagtgatctt
      601 gagaatgtca atcttaagga tcgggaagta gaggtgcagg gtcaggaagg aaactttctt
      661 gggactgcct acctttctca gcaaaacaag ggcttgggct ggtttatcag caaagacaag
      721 gtggccttca atcaagcttt ctttgaaacg ttgtttagaa aagccaaaga aaagagaaac
      781 gcctactatc aagatgattt gacaactgcc tttcgtctct ttaatcaaga gggagatggc
      841 tttgggggtc tgacagtgga cctttatggc gactacgccg tcttttcttg gtataactct
      901 tatgtttatc agattcgtca gactatatca gaagccttta gacaggtttt ccctgaagtt
      961 ttaggagctt atgagaaaat ccgctttaag ggtttgaact atgaatctgc ccatgtttat
     1021 ggtcaagaag cacctgactt tttcactgtt ttagaaaatg gtgtcctgta tcaagtcttt
     1081 atgaatgatg gcttgatgac aggaattttc ctagaccagc atgaggttcg cggtagttta
     1141 gttgacggct tggctatggg taaatcctta ctcaatatgt tttcctacac agcggctttt
     1201 tcagtagctg cggccatggg aggagctagc catacaactt ctgttgatct agccaaacgt
     1261 tcacgagaat tgtctcaagc gcattttcag gcaaatgggc tcagcacaga cgagcatcgt
     1321 tttatagtca tggatgtctt tgagtatttc aaatatgcca aacgcaaaga cttgacctac
     1381 gatgtgattg tcctagatcc gcctagcttt gctcggaata aaaaacaaac tttctctgtg
     1441 gccaaggatt atcacaagtt gatttcccag agtcttgaga ttttaaatcc gggagggatt
     1501 atcattgcca gtaccaatgc tgccaatgtt tcccgtcaga aatttacaga acaaattgat
     1561 aaaggttttg caggaagaag ttaccagatt ttaaacaaat atggtcttcc agcagatttt
     1621 gcctataata aaaaagatga aagtagtaat tacctcaagg tgattagtat gaaggttagt
     1681 aaatgaaatt aatcgtttca gtaatgccaa gaagtttaga ggaggctcag gctctggatg
     1741 ccacgaggta cctggatgcc gacatcattg aatggcgtgc cgactatctg cctaaagaag
     1801 cgattttgca ggtagctcca gccatttttg aaaaattcgc aggccgtgag ttggttttca
     1861 cgctacgaac tcgctccgaa ggtggagaaa tcgacctttc tccagaagag tatatccatc
     1921 taatcaagga agttgcgcaa ctctatcaac cagactatat tgattttgag tactatagct
     1981 acaaggatgt ttttgaggaa atgctggact tcccaaatct tgttttgagt taccataatt
     2041 tccaagaaac acctgagaac atgatggaaa tcttgtcaga gttgacgatc ctaaatccaa
     2101 aacttgttaa ggttgcggtg atggctcaca cggagcagga tgtcttagac ttgatgaact
     2161 atacacgagg ctttaaaacc ctcaatcctg aacaggaata tgtgaccatt tctatgggta
     2221 aggtgggcaa ggtctctcgt atcactgcgg atgtgactgg ttcgagttgg tcttttgcca
     2281 gtctggatga ggttagtgcc cctgggcaga tttctctagc tagcatgaaa aaaatcaggg
     2341 agattttgga tgaagcttga tggctataca cgtttagctg cagttgttgc caatcctatt
     2401 aagcattcta tttctccctt catccacaat agagcctttg aggcgacagc taccaacggt
     2461 gcttatgtgg cttgggagat tgaagcgagt gacttggcag aaacagtggc caatattcgt
     2521 cgctaccaga tgtttggcat caatctgtcc atgccctata aggagcaggt gattccttat
     2581 ttggatgagc taagcgatga agcgcgcttg attggtgcgg ttaatacggt tgtcaatgag
     2641 aatggcaatt taattggata taatacagat ggcaagggat tttttaagtg cttgccttct
     2701 tttacaattt caggtaaaaa gatgaccctg ctgggtgcag gtggtgcggc taaatcaatc
     2761 ttggcacagg ctattttgga tggcgtcagt cagatttcgg tctttgttcg ttccgtttct
     2821 atggaaaaaa caagacctta cctagacaag ttacaggagc agacaggctt taaagtggat
     2881 ttgtgtgctt tagaatatgt ttctgaactg caagcaagga ttgccgagtc ggatttgcta
     2941 gttaatgcca ccagtgtggg catggatggc caatcctctc ctgttcctga aaacatagtc
     3001 ttaccagaaa ctcttttagt tgcagatatc atataccaac cctttgaaac accgtttttg
     3061 aaatgggcta gaagtcaggg caatccagca gtcaatggtc tgggaatgtt gctctatcaa
     3121 gctgcagaag cttttcaact gtggataggc aaggaaatgc cgacagaaga gatttggcag
     3181 tctttaacag aaaaatacca ataaagaaag ggagactctc ctatgaaaat cagaatcgat
     3241 attcctcatc atccttatga tattcagatt gaaaaaggtt gtatggccca ggctggtcag
     3301 tggttgcgag aactctggca accgcaaaag gtagtcattg tgacagataa ccatgtagcc
     3361 tctctctatg cagagaaggt caagctcagc ctagaagatg ctggttttca ggtagctgtt
     3421 tttgatttct tagaaggtga agaaagaaag aatttaacta ctgttcagaa agtctatgaa
     3481 tttctagtca agcaaggtct gactcgtagc gatggaatcg ttgctcttgg tggtggcgtt
     3541 gttggggacc tggctggctt tgtagcctct acctatatgc ggggtattca ctttgttcag
     3601 attccgacta gtttgacagc tcaggttgat tcttctatcg gtggaaagac aggcgttaac
     3661 acaccatttg ctaaaaatat ggtggggacc tttgcccaac cagatggggt tctgattgat
     3721 ccacttgttc ttgaaaccct cggaaaaaga gagttgattg aagggatggg tgaagttatc
     3781 aagtatggct tgattgagga tccagaactg tgggctctct tgacgggact gaatggttct
     3841 gttgagagca ttttggaaca tgcagagacc ttgattgaac attcttgtca ggtgaagcgc
     3901 aagatggtgg ttgaagatga gttggacaat ggtattcgtc tttacctcaa ttttggccac
     3961 actattggcc atgccatcga agcgactgcc ggttatggca aggtcatgca tggagaggct
     4021 gttgccatgg gaatggtaca gatttccaag attgctgagg aaaaaggcct catgccagct
     4081 ggcattaccc aatctatcac agagatgtgt cagaaattcg gcttgcctgt tgactatgaa
     4141 aattgggaag ttgacaagct ttatcaggct cttactcatg acaagaaagc gcgtggcaac
     4201 accttgaaat tggtcttggt gccagagctt ggttcagcga ccattcatcc agtttctctg
     4261 gaagagatga aagactactt ggtaaaataa ggagagtgta tgagatattt aactgcagga
     4321 gaatcacacg gcccccgtct aacagctatt attgagggaa ttccagctgg acttccattg
     4381 acagctgagg atatcaatga ggaccttaga cgccgtcagg gtggctacgg tcgtggtggt
     4441 cgtatgaaga ttgagaatga ccaggttgtc tttacttcgg gcgttcgcca cgggaagacg
     4501 acaggggcgc ctattactat ggatgtcatc aataaggacc accagaaatg gctggacatc
     4561 atgtctgcgg aggacattga agaccgcctt aaaagcaagc ggaaaattac tcatcctcgc
     4621 ccaggtcatg ccgatttggt tggggggatt aagtaccgtt ttgatgattt gcgaaattct
     4681 ttggagcgtt catcagctcg tgaaaccacc atgcgggtgg cagttggtgc agtagccaaa
     4741 cgcctcttgg ttgagctgga tgtggagatt gccaaccatg tcgtggtctt tggtggcaag
     4801 gaaatcgatg ttcctgaaaa tctgacagtc gctgaaatta agcaaagagc tgcccagtct
     4861 gaagtttcta ttgtcaacca agaacgagaa caggaaatca aggactatat tgaccaaatc
     4921 aaacgtgatg gtgataccat cggtggggtt gtggagacag tcgtcggagg cgttccagtt
     4981 ggtcttggtt cctatgtcca atgggataga aaattggatg caagattggc tcaagctgtt
     5041 gtctctatca atgcctttaa aggggtggaa tttggtcttg gctttgaggc tggttatcgt
     5101 aaaggcagcc aagttatgga tgaaattctc tggtctaaag aagacggtta tactcgccgt
     5161 accaataatc taggtggttt tgaaggtggt atgactaatg ggcaacccat cgttgttcgt
     5221 ggggtcatga aacccattcc tactctttat aaacctctta tgagtgtgga tatcgaaacc
     5281 cacgaacctt acaaggcaac cgtggagaga agtgatccga ctgctcttcc agctgcagga
     5341 atggtcatgg aagcagttgt agcaacggtt ctggcgcaag aaatcctcga aaaattctca
     5401 tcagataatc ttgaggaact aaaagaagcg gtagccaaac accgagacta tacaaagaac
     5461 tattaaggag ttcctatggc aaaaacaatc tatatcgcag gtcttgggtt gattggagcc
     5521 tctatggcac ttggtatcaa acgcgatcat ccagattatg aaattttagg ttataatcgt
     5581 agtcaagctt cgagagatat cgccttgaaa gaaggcatga ttgaccgtgc aacggatgat
     5641 tttgctagtt ttgctccttt ggcagatgtc attatcctca gcttgccaat caaacaaact
     5701 attgctttca ttaaggagtt ggccaatttg gatttgcgag aaggcgttat tatttcagat
     5761 gctggttcga ccaagtcaac cattgtggat gcggcggagc agtatttggc tggcaagtct
     5821 gttcgctttg tcggggccca tcccatggct ggtagtcaca agacaggggc tgcttcggca
     5881 gatgtcaatc tttttgaaaa tgcctattat atctttacac cttcaagcct gacaagtcag
     5941 gacacgctta aggaaatgaa gtatctgctt tcaggtcttc atgctcgttt tatcgagatt
     6001 gatgccaagg agcatgatcg tgtcacttct cagattagcc attttcctca tattttggct
     6061 tctagtctca tggagcagac tgcggtctat gctcaagagc atgagatggc aaggcgcttt
     6121 gcggcaggtg gttttcgaga tatgacccga attgcggaaa gcgagccagg aatgtggacc
     6181 tccattctct tgtccaatag cgagaccatt ctggatagaa ttgaggattt caaggaacgt
     6241 ttggaagtga ttggtcaggc cattagtaag ggagatgaag agcaaatttg gaactttttt
     6301 aaccaagcgc gtgaacaacg ccagaccatg gaaatccata agcgtggtgg tgtggatagc
     6361 tcttacgacc tctatgttga cgttcctgat gaagaagatg tcatcctgcg gattttggaa
     6421 ctgctacgtg gaacttcctt ggttaacatc cacatcaacg aggaaaatcg tgaggatatt
     6481 cacggaatcc tacaaatttc atttaaaaat gctcaagact tggaaagagc tgagcatctc
     6541 ataacagaaa ataccgacta tacagtcgtc atcaaataag gagaagaaca tgtcaaatat
     6601 ttacgatagt gcaaacgaac tcagtcgcgg tctacgcgga ttaccagaat acaaggctgt
     6661 taaagcagct aaagatgcga ttgcagcaga tgctgaggca agcaaaatct ttacagaata
     6721 tcttgccttt caagaggaaa ttcaaaaact agcacagaca ggtcaaatgc cagatgcgtc
     6781 cttccaagct aagatggaag gctttggtaa acagattcaa ggaaatagcc tcttgtcaga
     6841 attctttacc aagcaacaac aattggccat ttacctttct gacattgaaa aaattgtttt
     6901 tgaaccagtt tcagaattgc tgaaataaga aaagaacgat cctaaagtca ggaattttta
     6961 aggaatttct ggctttttat gataaaatag gtaaaagtat tgcaagtatg aggtccagta
     7021 tgaaactaaa aacaaacatt cgccatttac atggtagtat ccgcgtccca ggtgacaagt
     7081 ctatcagcca ccgttccatt atctttggaa gtttggctga gggtgagacc aaggtttatg
     7141 atattctgcg aggtgaagac gttctttcga ccatgcaggt ttttcgtgac cttggtgttg
     7201 aaattgagga taaagatggg gttattacca ttcaaggtgt aggcatggct ggcttaaaag
     7261 cgccacaaaa tgcccttaat atgggaaatt ctggcacctc gattcgcctg atttcaggtg
     7321 tccttgctgg tgcagatttc gaagtagaga tgtttggaga tgatagtctt tccaaacgtc
     7381 ctatggaccg tgtgaccctt ccactgaaaa aaatgggcgt cagcatttca gggcaaactg
     7441 aacgagactt gcctcccctt cgcttaaaag ggacgaaaaa cctaagacct attcattatg
     7501 agttgccaat tgcctctgcc caagtcaagt cagccttgat gtttgcagcc ttacaagcta
     7561 agggggagtc agttattatc gaaaaagagt gcacccgtaa tcatactgaa gatatgttga
     7621 aacaatttgg tggtcattta agtgtggatg gtaagaaaat cacagtccaa gggccacaaa
     7681 aattgacagg acagaaggtg gtcgtaccag gagatatttc cagtgcagcc ttttggttag
     7741 tcgcaggttt gattgttcca aattctcgtc tagtgctgca gaatgtgggg atcaacgaaa
     7801 ctcgcaccgg tattattgat gtcattcgtg ccatgggtgg aaaattggaa ataactgaaa
     7861 tcgatccagt cgctaaatct tctaccttga ctgttgagtc ttctgacttg aaaggaacag
     7921 agattggtgg cgctttgatt ccacgattga ttgatgaatt gcccattatt gccctgcttg
     7981 cgactcaagc ccaaggtgta acagttatca aggatgctga ggagctcaag gtcaaggaaa
     8041 cagaccgtat tcaggttgtg gcagacgcct taaatagtat gggagcagat attactccta
     8101 cggcagatgg gatgattatc aaagggaaat cagctcttca cggtgctaga gtcaatacgt
     8161 ttggtgacca ccgtatcggc atgatgacag ctatcgcagc cctcttggtt gcagatggag
     8221 aggtggagct tgaccgtgca gaagccatca ataccagcta tcctagtttc tttgatgatt
     8281 tggagagctt gattcatggc taaggtgtta ttagggttta tgggggctgg aaaatcgact
     8341 attgcaagag gcttggaccc taattacctt gatatggatg ctctgattga gaagcgccta
     8401 ggtatgtcca ttgcgaattt tttcgctgaa aagggagaag cagcctttcg tcaggtagaa
     8461 tcagaagtcc tagctgattt actacaaaca gaccaagtcg tgtcaactgg aggaggagtg
     8521 gttatttctc agagaaatcg tgacttactc aagactaata cagataacat ctacctgaaa
     8581 gcagattttg aaaccctcta ccaacgtatc gcagctgata aggacaatca gcgaccgctt
     8641 tttctaaata atagcaagga agaactagta gctatttttc aagaaagaca ggcttggtat
     8701 gaggaagtgg ctagtcgggt tttggatgtg accaagctaa gcccagagga aattatagag
     8761 gaactaagat gaaaattgct tatctaggtc ccaaaggatc attttcacac cacgttgtgc
     8821 agacagcttt tcctcatgag gaattgcagg cttttgccaa cattacagat gtcatcaagg
     8881 cttatgagca aggattagtg gactattctg tggtgccagt tgaaaattct attgagggta
     8941 gtgttcatga aaccttggac tatctttttc atcaggctca catccaagca gtagcagaaa
     9001 tcgttcagcc tattcatcag cagttgatgg tggttccagg ccatactaag attgaaaaga
     9061 ttttttcaca tccacaggcc ttggctcaag gaaagaaatt catcgatgaa caatatccag
     9121 aggctcaaat cgaggtaaca gctagtacag cttatgcggc ccgttttatt tccgaacatc
     9181 cagaccagcc ctttgcagca gttgcaccta gaagttctgc tgaagaatat ggattggaac
     9241 tgattgccga ggatattcag gaaatggaag ccaatttcac acgtttctgg gttctaggag
     9301 ctgaaaagcc tagtattccc ttgcaagcac aaactgaaaa gatgagtttg gccttgacat
     9361 tacctgacaa ccttccaggt gcactttata aggccctgtc gacctttgct tggcgaggaa
     9421 ttgacttgac aaaaattgaa agtcgtccac tcaagacagc actgggtgaa tactttttca
     9481 ttatcgatgt ggattatacc gataaggact tggtccactt tgcccaaaaa gaattagaag
     9541 cgattggaat ccagtataaa attctgggtg cctatcctat ttatccaata tcagaccatg
     9601 gaaaggagag aagatgagta aagaaaatcc cttaagtcat catgagcagt tgcgttatga
     9661 ttatttgcta aaaaatattc actatctcaa tgagagagaa aaaaatgagt ttgcctattt
     9721 gcaagaaaag ctaactcttg ctaggggaaa tagtagctct agcttggaac aagaaagaga
     9781 agagcaggtt gacttaccaa gctatgcgaa ccggagtcgc tcacaatcca aatcacaagc
     9841 actctcttcc cctccaaaaa agaaaagacg gaagctccgt cttaaacgaa tttttatggt
     9901 gattttttca cttttggtct gtgtggcttt ggccatggta ttcatgtttt tgcgtggtta
     9961 ccaagatgct agcgcaaaga aaactgctga tgcccgggca gctcaagtag aagtctttaa
    10021 tggtcaggac actagagatg gagttaatat tttaatcatg ggtactgatg gtcgaatcgg
    10081 ccagaacagt gttgagacac gaactgactc tattatggta ttaaatgtcg ggggctcaga
    10141 taagaaaatg aagctagtca gtttcatgcg tgataatttg gtctatatag atggttatag
    10201 tcaagtgatt aacggtagaa aacagacaga taacaagtta aacgtagcct acgagttagg
    10261 agaacaagag gggcaaaaag gggcagaaat ggttcgccaa gtcttgaaag ataattttga
    10321 cttggacatt aagtactacg ccttggttga tttccaggcc tttgccacag cgattgacac
    10381 gcttttccct gatggggtga cgattgatgc tcaattttca acattgaatg ggcgtcccct
    10441 aacagaagct acagtcggag atgatttata cgctaccgag actgagtctc caacccaaac
    10501 cattaaagtc ggaaaacagc agatgaatgg ctcgaccctg ctcaattatg ctcgtttccg
    10561 tgatgatgat gaggcggatt acggccgtac aaaaagacag caacaagttt taacagcaat
    10621 tttagagcaa attaaagatc ccactaaact tttcactggt tctgaagctc ttggaaaggt
    10681 ttttgctatg acctcaacca acgtacccta tactttcctc ctaacaaacg gtttatctgt
    10741 tttggatgga gcaaaaaatg gtattgaaaa attgacgatt ccagaactgg gtgactgggt
    10801 agatgcctat gatgtttatg gaggcttggg cttgctggtt gatcaaaaca aatatcaaac
    10861 caagctcgct caaatggact tgagataaga taatactcaa tgaaaatcaa agtgcaaact
    10921 aggaagctag ccgcaggctg ctaaaaacac agttttgagg ttgtagataa gactgacgaa
    10981 gtcagttacc tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga
    11041 gtataagaca gaaaaatcaa agtttgatag ctatttggat agcagtcagg ctttgatttt
    11101 ttacagtctg caatagattt tcaccccttg tttgtggtat aatgaaacga tacgatagaa
    11161 agaataatga acaatatgac tgatttaaaa gcaattcagg ctcgtagtct ggagatggct
    11221 gaatattttg tggccttttg taaagaacat gatttgctct gttatctctg tggcggaggc
    11281 gctattggtg cccttcgaaa caagggattt attccttggg acgacgacct agactttttt
    11341 atgcctcgta aagattatga gaaattagca gaattatggc ctcgttatgc agatgaacgt
    11401 tatttcttgt caaagagtca caaggatttt gttgatcgta atctttttat taccattcgt
    11461 gacaaggaaa ccacctgtat caagccttat cagcaggatt tggatttgcc acatggtctg
    11521 gccttggatg ttttgccttt ggattattat ccgaaaaatc cagctgagcg gaaaaaacag
    11581 gttcgttggg ccttgattta ttcactcttt tgtgcgcaaa ctattccaga aaagcatggt
    11641 gctctcatga aatggggaag tcgcatttta ctgggtttga ctccaaaatc tctctgttat
    11701 cgcatctgga aaaaagctga gaaagaaatg actaagtatg atttggctga ttgtgatggc
    11761 attacagaat tatgctcagg tcctggctac atgagaaaca agtacccaat cacatctttt
    11821 gaagacaatc ttttcttgcc atttgaagga acagagatgc ctattccaat cggctatgat
    11881 gtctatctca gaactgcttt tggggattat atgacgcctc caccagcaga caagcaggta
    11941 ccgcatcatg atgctgtcat cgctgatatg gataagtctt atacagaata caagggagaa
    12001 tatggtggct aagaaaaaaa tcttattttt tatgtggtct ttttctcttg gaggtggtgc
    12061 agagaagatt ctatcaacca ttgtttcaaa tctggatcca gaaaagtatg atattgatat
    12121 tcttgaaatg gagcactttg acaagggata tgaatctgtt ccaaagcatg tacgcatttt
    12181 aaaatccctt caagattatc gccaaaccag atggttacga gcttttttgt ggagaatgag
    12241 aatttatttt ccaagactgg ctcgtcgttt gcttgtaaaa gatgattatg atgttgaagt
    12301 ttcttttacc attatgaatc caccactgtt gttctctaaa agaagagaag tcaagaagat
    12361 atcttggatt catggaagta ttgaagaact tcttaaggat agctctaaaa gagaatcaca
    12421 tagaagccag ttggatgctg cgaatacaat tgtagggatt tcaaaaaaga ccagcaattc
    12481 tatcaaggaa gtttatccag attatgcttc taaattacag acaatctaca atggatatga
    12541 ttttcagact attctagaaa aatctcaaga gaagatcgat atcgagattg ctcctcaaag
    12601 tatctgtact atcggacgga ttgaggaaaa taagggttct gaccgtgtag tggaagtgat
    12661 acgattatta caccaagagg gaaaaaacta tcatctctat tttatcgggg ctggtgatat
    12721 ggaagaggaa ctgaaaaaac gagtcaaaga gtatgggatt gaggactatg tacatttcct
    12781 tggttatcaa aaaaatcctt atcagtatct atctcagacg aaagttcttt tgtctatgtc
    12841 taaacaagaa ggttttcctg gagtgtatgt ggaggccttg agtctgggac tcccttttat
    12901 ctctacgaac gttggagggg ctgaggaatt atcccaagaa ggacgatttg gacaaatcat
    12961 tgagagcaat caagaggcag ctcaggcgat tactaattac atgacttctg cctcaaactt
    13021 tgatgtcgat gaggctagcc aattcattca acaatttaca attacaaaac aaatcgaaca
    13081 agtagaaaaa ctattagagg agtagcatgg aaactgcatt aattagtgtg attgtgccag
    13141 tctataatgt ggcgcagtac ctagaaaaat cgatagcttc cattcagaag cagacctatc
    13201 aaaatctgga aattattctt gttgatgatg gtgcaacaga tgaaagtggt cgcttgtgtg
    13261 attcaatcgc tgaacaagat gacagggtgt cagtgcttca taaaaagaac gaaggattgt
    13321 cgcaagcacg aaatgatggg atgaagcagg ctcacgggga ttatctgatt tttattgact
    13381 cagatgatta tatccatcca gaaatgattc agagcttata tgagcaatta gttcaagaag
    13441 atgcggatgt ttcaagctgt ggtgtcatga atgtctatgc taatgatgaa agcccacagt
    13501 cagccaatca ggatgactat tttgtctgtg attctcaaac atttctaaag gaatacctca
    13561 taggtgaaaa aatacctggg acgatttgca ataagctaat caagagacag attgcaactg
    13621 ccctatcctt tcctaagggg ttgatttacg aagatgccta ttaccatttt gatttaatca
    13681 agttggccaa gaagtatgtg gttaatacta aaccctatta ttactatttc catagagggg
    13741 atagtattac gaccaaaccc tatgcagaga aggatttagc ctatattgat atctaccaaa
    13801 agttttataa tgaagttgtg aaaaactatc ctgacttgaa agaggtcgct tttttcagat
    13861 tggcctatgc ccacttcttt attctggata agatgttgct agatgatcag tataaacagt
    13921 ttaaagccta ttctcagatt catcgttttt taaaagacca tgcctttgct atttctagga
    13981 atccaatttt ccgtaagggg agaagaatta gtgctttggc cctattcata aatatttcct
    14041 tatatcgatt cttattactg aaaaatattg aaaaatctaa aaaattacat tagaacgggg
    14101 gtgaccaagt gattgatggg aaacgattat tatttagttt gaccatagtc agttatgcct
    14161 tgacgctagt aagtggaatt gtgtatctgt ttaataataa taatgttagc ttactttcta
    14221 ctttattgtt cttgttggtt agtagcttga ttgcttgttg gaatgatatc aagtattact
    14281 taatccattt tattttctat ttaaccattt ttgtatttct ggtatcaaga ccgaccattg
    14341 attattttag ggatggtgct ttggatacct atcatccaat agcctatcgt tttgccttta
    14401 tagttgtcat ggtttcgatt ctgggcttga caacaggagg cgtcctggct cgttacttca
    14461 tagctaggaa gaaaataaaa gtagcaaata taggaaattc tctaaaagag gtttatatca
    14521 agcggttacg ctttgtatca ctaggagttt ttcttctaac ttatcctttc tatttcattc
    14581 ggttatttga acggctcttg tatcgtttgc agacttccta ctatgcctac tatgcaaatt
    14641 ttgaaagtaa actgccttat tttacctaca ttttgtctac ctttacggtc tatgcaatgt
    14701 gtatgtatct ggcaaccaag ccaaagaaat tgcaggccac agcagtgctt gtctccttta
    14761 ttgcagctaa cactattcat ttggcaattg ggacacgaaa tccctttatt ttaagtattt
    14821 tatttgcttt tgtttattac tttatgcggg agcaagctga aaaaggaaaa tggattgggt
    14881 ttaaagaaaa gttagcgatt tttgtaggtt ctcctattct catgttagcg atgggagtac
    14941 tcaattatgt acgggataat gtccaagttt cccatacagg tttctgggat atcttacttg
    15001 actttatcta taaacaaggg actagttttg gtgttctggc tcgaggtttt ctatttaaca
    15061 gtagcctccc ttaccgagat ttccgtaatt ttacttttgg tcctgttctt gattattttg
    15121 caagggggag tttgggagcc attttcggag gaaaagcctt tgaacataca accaatagtg
    15181 tggaactagc tattgatagt aatagttatg cccacaatct atcctatctt gtcttgaaca
    15241 aggaatactt gaaagggcat ggtatcggaa gtagttatat catggagttg tataccgact
    15301 atggtatgat tggagtcttt ctgcttagtt tcttactcgg cgtattattt atagccatgc
    15361 tgcaagtagc ctatcgctca aggataatcc tatttgcttt atccctactc atcttgaata
    15421 atctattctt tatgccaaga agcagctttt cagaaagttt cttcaattta tttacaatgc
    15481 aattctgggg aattgttctt gtgattatat ttgtagcaaa aatgtttaca aaggaaaact
    15541 agtatctact aaacaaagga gaaaaaaatc atgtttgaac attattcagt agctgatttg
    15601 tttgcaaatc tttataaaaa gcgaaaagca aatattttag ctctcatcgc tttatttgct
    15661 ctcattgctg taccatttac aattaaagca gttaggaata aaaacactgt caaagataca
    15721 acaagttatt caacttatct tatctataaa atcactcctc caaaagagtc ggccaaaacg
    15781 attttgaatc atcaaattgg tggttatagt gatttttatg ggaaattgat tgatggtaat
    15841 ttgaatggag cttatctttt caatgatgta gaacccagtg agttgaaaaa aattgccagt
    15901 gaattagaca cgacagaaac aaccttgaaa aattcaacga atgactattg gtggaaaaaa
    15961 ttgaccgtct actatatgat tgacgatgca ggggttggtg tgaaaatttt gacatcaagt
    16021 aaagatgcca atgacttgtt agagaaaaaa attgatgggt tgattgagaa atttaaacat
    16081 gcctatgcaa atgtgaaaat tgaaaaactg gaaaccatca actctaaaga attgaacgca
    16141 aatggtgaaa cagcgcttgg cttaaatgtg aaaaatctga ttcttcgttt agttgttatt
    16201 ggagtggttt gtgtgatttt ggttgtgatg ggaaatgtgt tagtttatct ctttaatcca
    16261 acaatcaata gagtaggtga tttttctcag tatcaaattg attttgtaac agagattaca
    16321 acaattgcta acctagcaga tgttttgtca tacaaaaata ctggacagga attgaccatc
    16381 gttagctcaa ataaagctat cctagataaa ttgaaacaga gtcaagaagc tttaaaagga
    16441 atgcattttg tagatttaca ggatgtatca tctcttttgg aaagagatac agtccttctt
    16501 gttgaagagt acggagtgac tcgttataag aaatttgagc aaagtcttca aattctcaga
    16561 aacttaaatc gttctatcct tggtgtagca acctttaaat tataagtatt ctgatgtata
    16621 aggtcttcaa aatcggctaa gagctgattt tgaaggcttt ttctatctgt ctgcagaaat
    16681 tttcttttgg agtctcctat agaaagaccc tagggaaaat ctatccgtat agaggagcct
    16741 tcttttgata aaatcgtaaa aatctagtat aatagataga actgaaagta tgaggttact
    16801 agcaatgaaa atgaaacaaa ttagtgatac aactttaaaa atcacgatgt ctttagagga
    16861 tttgatggat cgtggaatgg agattgctga ctttctcgtt cctcaagaaa aaacagaaga
    16921 gttcttttat gctatcttgg atgagctaga gatgcctgat agctttctgg atacaggcat
    16981 gttgagcttc cgtgtgactc caaaacctga taaggtagat gtctttgtga ccaagtcaaa
    17041 gattgaccaa aatctagatt ttgaagactt atcggatttg ccagatatgg aagaattggc
    17101 tcaaatgtct ccagatgaat ttatcaaaac cctggaaaaa agcatcgcag acaaaaccaa
    17161 ggatgatatc gaagccattc aatctcttga gcaagttgaa gccaaggaag aagagcaaga
    17221 gcaggctgaa caagaagctg agagtaagaa agaaccttac atctactaca tcctttcttt
    17281 tgctaagttg gctgacttgg tagtttttgc caagacagtg acttttgaaa tggaaacttc
    17341 tgaactctac aaaatgaacg agcgctatta tttgaccatt ttagtggata ttgaaaatca
    17401 tccaagccca tatccagctt ggctgttggc ccgtatgcgc gagtttgcag acgatagtga
    17461 tatcagtcgc tcagtcttac aagagtatgg tcaagtcttg atgagtcacg atgcagtgct
    17521 caatctgcaa aaaatcggct aatcctttct ggaaagctat tttcagattt taagaagagc
    17581 gaatcgtctg attcgttttt tctttttata ctgaaatagt gatttactat aataggaatt
    17641 ttcacaaaat tctgttataa tggctatatt agaaaatttc gaggagataa agatgacagt
    17701 taaaattgct ttactaggat ttggtaccgt tgcaagtggt gtgcctttcc tcctaaagga
    17761 aaatggagga aaaatcaatc aatcagcaca ttcagatatc aaagttgcta aggtattggt
    17821 caaggatgaa gatgaaaaaa atcgcttgct tgcagcaggg aatgacttta actttgtaac
    17881 caatgtggat gatattttat cagaccagga tattactatc gtagtggaat tgatggggcg
    17941 tattgagcct gctaaaacct ttatcactcg tgccttggaa gctggaaaac acgttgttac
    18001 tgctaacaag gaccttttag ctgtccatgg cgcagaattg ctagaaatcg ctcaagctaa
    18061 caaggtagca ctttactacg aagcagcagt tgctggtggg attccaattc ttcgtacttt
    18121 agcaaattcc ttggcttctg ataaaattac gcgcgtgctt ggagtagtca acggaacttc
    18181 caacttcatg gtgaccaaga tggtggaaga aggctggtct tacgatgatg ctcttgcgga
    18241 agcacaacgt ctaggatttg cagaaagcga tccgacgaat gacgtagatg ggattgatgc
    18301 agcctacaag atggttattt tgagccaatt tgcctttggc atgaagattg cctttgatga
    18361 tgtagcccac aagggaatcc gcaatatcac accagaagac gtagctgtag ctcaagagct
    18421 tggttacgta gtgaaattgg ttggttctat tgaggaaact tcttcaggta ttgctgcaga
    18481 agtgactcca accttcctac ctaaagcgca cccacttgct agtgtgaatg gcgtaatgaa
    18541 cgctgtcttt gtagaatcta tcggtattgg tgagtctatg tactacggac caggtgctgg
    18601 tcaaaaacca actgcaacaa gtgttgtagc tgatattgtc cgtatcgttc gtcgtttgaa
    18661 tgatggtact attggcaaag acttcaacga atatagccgt gacttggtct tggcaaatcc
    18721 tgaagatgtc aaagcaaact actatttctc aatcttggct ctagactcaa aaggtcaggt
    18781 cttgaagttg gctgaaatct tcaatgctca agatatttcc tttaagcaaa tccttcaaga
    18841 tggcaaagag ggtgacaagg cgcgtgtcgt tatcatcaca cacaagatta ataaagccca
    18901 gcttgaaaat gtctcagctg aattgaagaa ggtttcagaa ttcgacctct tgaatacctt
    18961 caaggtgtta ggagaataag atgaagatta ttgtacctgc aaccagtgcc aatatcgggc
    19021 caggttttga ctcggtcggt gtagctgtaa ccaagtatct tcaaattgag gtctgcgaag
    19081 aacgagatga gtggctgatt gaacaccaga ttggcaaatg gattccacat gatgagcgta
    19141 atctcttgct caaaatcgct ttgcaaattg taccagactt gcaaccaaga cgcttgaaaa
    19201 tgaccagtga tgtccctttg gcgcgcggtt tgggttcttc cagctcggtt atcgttgctg
    19261 ggattgaact agccaaccaa ctgggtcaac tcaacttatc agaccatgaa aaattgcagt
    19321 tagcgaccaa gattgaaggg catcctgaca atgtggctcc agccatttat ggtaatctcg
    19381 ttattgcaag ttctgttgaa gggcaagtct ctgctatcgt agcagacttt ccagagtgtg
    19441 attttctagc ttacattcca aactatgaat tacgtactcg cgacagccgt agtgtcttgc
    19501 ctaaaaaatt gtcttataag gaagctgttg ctgcaagttc tatcgccaat gtagcggttg
    19561 ctgccttgtt ggcaggagac atggtgaccg ctgggcaagc aatcgaggga gacctcttcc
    19621 atgagcgcta tcgtcaggat ttggtaagag aatttgcgat gattaagcaa gtgaccaaag
    19681 aaaatggggc ctatgcaacc tacctttctg gtgctgggcc gacagttatg gttctggctt
    19741 ctcatgacaa gatgccaaca attaaggcag aattggaaaa gcaacctttc aaaggaaaac
    19801 tgcatgactt gagagttgat acccaaggtg tccgtgtaga agcaaaataa agaatagaag
    19861 ataggatggg gaaactcttg accagagggt ttcatatcct ttttgtgaaa agaagtttat
    19921 actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca aaacagtgtt
    19981 ttgaggttgc agatagaact gacgacgtca gtaacatata tacggtaagg tgacgctaac
    20041 gtggtttgaa gagattttcg aagagtatta gttaaaaacg tgataaagga gaaataaaga
    20101 tggcagaaat ttatctagca ggtggttgtt tttggggcct agaggaatat ttttcacgca
    20161 tttctggagt gctagaaacc agtgttggct acgctaatgg tcaagtcgaa acgaccaatt
    20221 accagttgct caaggaaaca gaccatgcag aaacggtcca agtgatttac gatgagaagg
    20281 aagtgtcact cagagagatt ttactttatt atttccgagt tatcgatcct ctatctatca
    20341 atcaacaagg gaatgaccgt ggtcgccaat atcgaactgg gatttattat caggatgaag
    20401 cagatttgcc agctatctac acagtggtgc aggagcagga acgcatgctg ggtcgaaaga
    20461 ttgcagtaga agtggagcaa ttacgccact acattctggc tgaagactac caccaagact
    20521 atctcaggaa gaatccttca ggttactgtc atatcgatgt gaccgatgct gataagccat
    20581 tgattgatgc agcaaactat gaaaagccta gtcaagaggt gttgaaggcc agtctatctg
    20641 aagagtctta tcgtgtcaca caagaagctg ctacagaggc tccatttacc aatgcctatg
    20701 accaaacctt tgaagagggg atttatgtag atattacgac aggtgagcca ctcttttttg
    20761 ccaaggataa gtttgcttca ggttgtggtt ggccaagttt tagccgtccg atttccaaag
    20821 agttgattca ttattacaag gatctgagcc atggaatgga gcgaattgaa gttcgttctc
    20881 gttcaggcag tgctcacttg ggtcatgttt tcacagatgg accgcgggag ttaggcggcc
    20941 tccgttactg tatcaattct gcttctttac gctttgtggc caaggatgag atggaaaaag
    21001 caggatatgg ctatctattg ccttacttaa acaaataaaa cagagagtgg gacttcccac
    21061 tttcttcatt tctagaatat gaatagaagg gatttatgaa acacctatta tcttacttca
    21121 aaccctacat caaggaatca attttagccc ccttgttcaa gctgttagaa gctgtttttg
    21181 agctcttggt tcccatggtg attgctggga ttgttgacca atctttacct cagggagatc
    21241 aaggtcatct ctggatgcag attggtctgc tccttatctt tgcagtaatt ggcgttttag
    21301 tggccttgat agctcaattt tactcagcaa aggcagcagt aggttttgct aaggaattga
    21361 caaacgatct ttatcgtcat attctttcct tgccaaagga cagcagagac cgtctgacaa
    21421 cttctagttt ggtcactcgc ttgacttcgg atacctacca gattcagact ggtatcaatc
    21481 aattcctgcg tctcttttta cgagcgccca ttatcgtttt tggtgccatt tttatggctt
    21541 atcgaatctc agctgagttg actttctggt tcttagtcat ggttgccatt ttgaccattg
    21601 tcattgtagg gttatctcga ttggtcaatc ctctctacag tagtctcaga aagaaaacgg
    21661 accaactggt tcaggaaacg cgccagcaat tgcaagggat gcgggttatt cgtgcttttg
    21721 gtcaagaaaa actagagtta cagatttttc aaacccttaa ccaagtttat gctagattac
    21781 aagaaaagac aggtttctgg tctagtttat taacacctct gacctatctg attgtcaatg
    21841 gaactcttct cgttattatc tggcaaggct atatttcaat tcaaggagga gtgctcagtc
    21901 aaggtgctct cattgctctt atcaattacc tcttacagat tttggtggaa ttggtcaagc
    21961 tagccatgtt gataaattcc ctcaaccagt cctatatctc agccaagcga atcgaggaag
    22021 tctttgttga ggctccagag gatatccatt cagaattaga acaaaagcaa gttaccagtg
    22081 atcgggtttt acaagtccaa gaattgacct ttacctatcc tgatgcggcc cagccttctc
    22141 tgagagacat ttcctttgat atgattcaag gacaaatcct tggtatcatt ggggggactg
    22201 gttctggtaa atcaagcttg attcaactca tacttggact ttatccagta aataagggaa
    22261 gaattgacct ttatctagat ggactgagtc ctcttaattt ggagcaatgg agatcttgga
    22321 ttgcctatgt gccacaaaag gtcgaactct ttaagggaac tattcgttcc aacttgactt
    22381 taggtttcaa tcaagaagtg actgatcaag aactctggca agccttggaa attgctcaag
    22441 ctaaggattt tgtcagtgat aaggaaggac tcttggatgc tctagttgaa gcaggggggc
    22501 gaaatttctc aggtggacaa aaacaaaggc tgtctatcgc acgagcagtc ttgcgccagg
    22561 ctccgtttct catcctagat gatgcgacct cggcactgga caccattacc gagtccaaga
    22621 tcttgaaagc tatccgcgaa aatctgccaa atatgagctt aatcttgatt tctcaacgga
    22681 cttcgacact ccagatggcg gaccagattc tcctcttgga aaaaggtgag ttgctagctg
    22741 ttggcaagca cgatgacttg atgaaatcca gccaagtcta tcgtgaaatc aatgcatccc
    22801 aacatgaaaa ggaggactag aatgaaacga caaactgtaa accagacgct caaacgttta
    22861 gccgtagatt tagcaagcca tcctttcctc cttttcctag cctttctagg aactattgcc
    22921 caagttggct tatcaattta cctacctatt ctgattgggc aggtcattga ccaagtccta
    22981 gtggctggtt catcactagt tttttggcag atttttctcc atatgctctt ggttgtaata
    23041 ggaaatactc tggtacaatg ggccaatcct ctcctctata atcgcctaat tttctcttat
    23101 accagagact tgcgagagcg aatcatccat aagctccatc gtttaccgat tgcctttgta
    23161 gataggcaag gtagtggaga gatggttagt cgtgtaacca cggacatcga acagttggca
    23221 gctggcttga ccatgatttt taaccaattt ttcattggtg ttttgatgat tttggttagt
    23281 attctagcca tgctccaaat tcatctcctc atgactctct tagtcttgct gttgacgcca
    23341 ctgtccatgg tgatttcacg ctttattgcc aagagatcct atcatctctt ccagaagcaa
    23401 acagagacga ggggaattca gactcagttg attgaagaat cgcttagcca gcagactata
    23461 atccagtcct tcaatgctca aacagaattt atccaaagat tgcgtgaggc tcatgacaac
    23521 tactcaggct attctcagtc agccatcttt tattcttcaa cggtcaatcc ttcgactcgc
    23581 tttgtaaatg cactcattta tgctctttta gctggagtag gagcttatcg tatcatgatg
    23641 ggttcaacct tgaccgtcgg tcgtttagtg acttttttga actatgttca gcaatacacc
    23701 aagcccttta acgatatttc ttcagtgcta gctgagttgc aaagtgctct ggcttgcgta
    23761 gagcgtatct atggagtttt agatagccct gaagtggctg aaacaggtaa ggaagtcttg
    23821 accagtgacc aagttaaggg agctatttcc tttaaacatg tctcttttgg ctaccatcct
    23881 gaaaaaattt tgattaagga gttgtctatc gatattccag ctggtagtaa ggtagccatc
    23941 gttggtccga caggtgctgg aaaatcaact cttatcaatc tccttatgcg tttttatccc
    24001 attagctcgg gagatatctt gctggatggg caatccattt atgattatac acgagtatca
    24061 ttgagacagc agtttggtat ggtgcttcaa gaaacctggc tcacacaagg gaccattcat
    24121 gataatattg cctttggcaa tcctgaagcc agtcgagagc aagtaattgc tgctgccaaa
    24181 gcagctaatg cagacttttt catccaacag ttgccacagg gatacgatac caagttggaa
    24241 aatgctggag aatctctctc tgtcggccaa gctcagctct tgaccatagc ccgagtcttt
    24301 ctggctattc caaagattct tatcttagac gaggcaactt cttccattga tacacggaca
    24361 gaagtgctgg tacaggatgc ctttgcaaaa ctcatgaagg gccgcacaag tttcatcatt
    24421 gctcaccgtt tgtcaaccat tcaggatgcg gatttaattc ttgtcttagt agatggtgat
    24481 attgttgaat atggtaacca tcaagaactc atggatagaa agggtaagta ttaccaaatg
    24541 caaaaagctg cggcttttag ttctgaataa gccattctct tttgaaagtt tatggacgaa
    24601 aaaagttgcc ttcgagtgac ttttttgtta caatagctag aaaaattgtt cactgtaata
    24661 ctcaatgaaa atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcacagctt
    24721 tgaggttgca gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgcagatag
    24781 aactgacgaa gtcagtaacc acacctacgg caaagtgaat ctgaagtggt ttgaagagag
    24841 tacaacttgt cttttagaaa aggagcctat aatgaaagtc tttcagcatg taaatatcgt
    24901 gacttgtgat caagatttcc atgtttatct tgatggaatc ttagcagtca aggattctca
    24961 aatcgtctat gtcggtcaag ataagccagc gtttttagag caagctgagc agattataga
    25021 ctatcaggga gcttggatta tgcctggttt ggtcaattgt cacacccatt ctgcaatgac
    25081 aggtctgaga gggatccgag atgacagcaa tctccatgaa tggctcaatg actatatttg
    25141 gccagcagaa tctgagttta ctcccgacat gactaccaat gcggtcaaag aagccctgac
    25201 agagatgctc cagtcaggaa caacaacctt taacgatatg tataatccca ttggtgtgga
    25261 tatccagcaa atttatcagg tggtgaaaac ttccaagatg cgttgttatt tttctccgac
    25321 tctcttttct tcagagacag aaacaactgc tgagactata agcagaactc gatccatcat
    25381 agatgaaatc ttaaaatata aaaatccaaa tttcaaggtt atggtagcac ctcattctcc
    25441 gtatagctgc agtagagact tgctggaagc gagtttggaa atggcaaaag agctaaatat
    25501 tccgctccat gtccatgtgg cggagaccaa ggaggagtca ggaattatcc tcaaacgata
    25561 cggcaaacgc ccccttgctt ttcttgaaga actgggttat ttagatcatc cgtccgtatt
    25621 tgctcacggg gtcgaattaa acgagagaga aattgaacgc ttggcatctt ctcaagtggc
    25681 tatcgcccac aatcctatca gtaacctcaa actggcatca ggaattgctc caattatcca
    25741 gctccaaaaa gcgggagtag cagtcggaat tgcgactgac tcggttgctt ccaataacaa
    25801 tctagatatg tttgaggaag gaaggactgc agctcttctt cagaagatga aaagtgggga
    25861 tgccagccag tttccaatcg aaacagctct caaggtactg acaatcgaag gggctaaggt
    25921 ccttggaatg gaaaatcaga taggaagtct ggaagtcggc aagcaagcag attttctggt
    25981 cattcaacca caagggaaaa ttcatctcca acctcaggaa aatatgctgt ctcacctggt
    26041 ttatgcagtt aaatctagtg atgtagatga tgtttatatc gccgaagaac aggttgttaa
    26101 gcaaggtcaa gtcctgacag tagaacttta aaagaaaaat tacgaaaaat tttaaaaaaa
    26161 gtttgcaaaa atcttgcatt ctttttttga ctatgctata cttatatacg gtttaaaaaa
    26221 actgcctaag acagtagggg agctcgactc ataaatatcc taccgaggac aaaacgtatc
    26281 atgtaaaaag aagcgtattg tactttcgtg tctaggtttg ggcgcgtttt tctttttgaa
    26341 aaattcccca agcaaaataa ttacggaggt gaacacacta atgagtgaag caattattgc
    26401 taaaaaagcg gaactagttg acgtagtagc tgaaaaaatg aaagctgctg catctatcgt
    26461 cgttgtagac gctcgtggtt tgacagttga gcaagataca gttcttcgtc gtgagcttcg
    26521 tggaagcgaa gttgagtata aagttattaa aaactcaatc ttgcgtcgtg cagctgaaaa
    26581 agctggtctt gaagatcttg catctgtatt tgttggacca tctgcagtag cattttctaa
    26641 tgaagatgtt atcgcaccag cgaaaatctt gaacgacttt tctaaaaacg ctgaagcact
    26701 tgaaattaaa ggtggtgcaa tcgaaggcgc tgtcgcatct aaagaagaga ttcttgcact
    26761 tgcaactctt ccaaaccgcg aaggacttct ttctatgctc ctttctgtac ttcaagcgcc
    26821 agtgcgcaac gttgctcttg cagtcaaagc ggttgcagaa agcaaagaag acgcggctta
    26881 atcttaagct acacagcgta gcttagctac gaaaaaaact attataaaat ttaaaactta
    26941 tttggaggaa ataacaatgg cattgaacat tgaaaacatt attgctgaaa ttaaagaagc
    27001 ttcaatcctt gaattgaacg accttgtaaa agctatcgaa gaagaatttg gtgtaactgc
    27061 agctgctcct gtagctgttg ctgcagctga tgcagctgat gctggtgctg ctaaagattc
    27121 attcgacgtt gaattgacat ctgcaggcga caaaaaagtt ggcgttatca aagttgtacg
    27181 tgaaatcact ggtcttggtc ttaaagaagc taaagaactt gttgacggtg caccagcact
    27241 tgttaaagaa ggcgttgcaa ctgcagaagc tgaagaaatc aaagctaaat tggaagaagc
    27301 tggagcttca gttactctta aataatagag caactacatt agtagcttaa aaacatgatt
    27361 aaaccgctat tcttaggagt agcggttttt ctttttgttt aaaaaggggc aaacttttta
    27421 tatagttgtt taggaaataa ataatttttg tataattggt ttactactct aaattaacgt
    27481 agtacaagag tttgttaatt aaactatacc ttatggtttt gactagtgtg atataattat
    27541 gttgaaatac ttatctggaa aggtttttat aatgagttta agaaataaaa ttgagcaaca
    27601 tattaaagag ctagagggag ggaagtttca aaaactaggt gacgcgtacc taagtagaaa
    27661 atacaatttt aatattgttt cattaggctc acaggaagga acagataaaa caactaaagg
    27721 gatcccagat tcttacgctg tcgaaaatgg taaatatgtt tatattatgt atggcaccca
    27781 taagtctgta atatctaaat tagaaggaga cattcagtca gttaagaaaa aaattttaga
    27841 ggaaaatatt gctgaagata aagttgggag acttatttgt tgtcatactt cttcaaatat
    27901 aacaattaaa caaaaagaag atctagaaaa aatggctgag ccttatcatc tagaattgat
    27961 tggaattaat gaaattgcta atgatcttac aaagatagat tttcaatatt tagcaaaaga
    28021 gtatctatca atcagtgaat ctacagagca agtttggtct atcaatgact tcataagaat
    28081 tcatgatgag agtaaaacta atgctcctat atcaaatgac tatattggag atgtaagtga
    28141 aattataaat accattaaat caagtgaaaa acgaatcttc ttaatatctg ctaagcctgg
    28201 aacagggaaa actagattag caattgaaat ttgctctttg ctggatcgaa ataaatataa
    28261 cattatttgt gtcaagagca ataatcagga tatttaccaa gatgtaaaac gcaatctaaa
    28321 tttacacaaa gaaaatattg t
//
LOCUS       DAVKXA010000025        27906 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKXA010000025 DAVKXA010000000
VERSION     DAVKXA010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.025"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(163..240)
                     /locus_tag="VW883_001158"
                     /pseudo
     CDS             complement(163..240)
                     /locus_tag="VW883_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            311..967
                     /locus_tag="VW883_001159"
     CDS             311..967
                     /locus_tag="VW883_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0274302.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTVLGDLLPNSEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            957..1280
                     /locus_tag="VW883_001160"
     CDS             957..1280
                     /locus_tag="VW883_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0274303.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1384..2214
                     /locus_tag="VW883_001161"
     CDS             1384..2214
                     /locus_tag="VW883_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0274304.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2368..3222
                     /locus_tag="VW883_001162"
     CDS             2368..3222
                     /locus_tag="VW883_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0274305.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLKNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAIPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3322..4695
                     /locus_tag="VW883_001163"
     CDS             3322..4695
                     /locus_tag="VW883_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0274306.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREIALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4688..5749
                     /locus_tag="VW883_001164"
     CDS             4688..5749
                     /locus_tag="VW883_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0274307.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5751..6443
                     /locus_tag="VW883_001165"
     CDS             5751..6443
                     /locus_tag="VW883_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274308.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQS
                     LGDFLTKKLSHK"
     gene            complement(6473..7042)
                     /locus_tag="VW883_001166"
     CDS             complement(6473..7042)
                     /locus_tag="VW883_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0274309.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7177..7791
                     /locus_tag="VW883_001167"
     CDS             7177..7791
                     /locus_tag="VW883_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0274310.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFTLSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7793..9439
                     /locus_tag="VW883_001168"
     CDS             7793..9439
                     /locus_tag="VW883_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0274311.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9451..10737
                     /locus_tag="VW883_001169"
     CDS             9451..10737
                     /locus_tag="VW883_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274312.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10789..11322
                     /locus_tag="VW883_001170"
     CDS             10789..11322
                     /locus_tag="VW883_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274313.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11400..11870
                     /gene="nrdI"
                     /locus_tag="VW883_001171"
     CDS             11400..11870
                     /gene="nrdI"
                     /locus_tag="VW883_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0274314.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12163..13425)
                     /locus_tag="VW883_001172"
     CDS             complement(12163..13425)
                     /locus_tag="VW883_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0274315.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13735..14193)
                     /locus_tag="VW883_001173"
     CDS             complement(13735..14193)
                     /locus_tag="VW883_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0274316.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14190..14630)
                     /locus_tag="VW883_001174"
     CDS             complement(14190..14630)
                     /locus_tag="VW883_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274317.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFVQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14836..16785
                     /gene="mutL"
                     /locus_tag="VW883_001175"
     CDS             14836..16785
                     /gene="mutL"
                     /locus_tag="VW883_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0274318.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17110..17577)
                     /locus_tag="VW883_001176"
     CDS             complement(17110..17577)
                     /locus_tag="VW883_001176"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0274319.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17578..18783)
                     /locus_tag="VW883_001177"
     CDS             complement(17578..18783)
                     /locus_tag="VW883_001177"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0274320.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRIHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18803..19438)
                     /gene="ribE"
                     /locus_tag="VW883_001178"
     CDS             complement(18803..19438)
                     /gene="ribE"
                     /locus_tag="VW883_001178"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0274321.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19423..20523)
                     /gene="ribD"
                     /locus_tag="VW883_001179"
     CDS             complement(19423..20523)
                     /gene="ribD"
                     /locus_tag="VW883_001179"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0274322.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20658..20772)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20929..21522
                     /gene="ruvA"
                     /locus_tag="VW883_001180"
     CDS             20929..21522
                     /gene="ruvA"
                     /locus_tag="VW883_001180"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0274323.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21532..22095
                     /locus_tag="VW883_001181"
     CDS             21532..22095
                     /locus_tag="VW883_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0274324.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22092..22769
                     /locus_tag="VW883_001182"
     CDS             22092..22769
                     /locus_tag="VW883_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0274325.1"
                     /translation="MMSNKNKEILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22906..23937)
                     /locus_tag="VW883_001183"
     CDS             complement(22906..23937)
                     /locus_tag="VW883_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0274326.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKSEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24192..24875)
                     /locus_tag="VW883_001184"
     CDS             complement(24192..24875)
                     /locus_tag="VW883_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0274327.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24887..25831)
                     /locus_tag="VW883_001185"
     CDS             complement(24887..25831)
                     /locus_tag="VW883_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0274328.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            complement(25987..27153)
                     /locus_tag="VW883_001186"
     CDS             complement(25987..27153)
                     /locus_tag="VW883_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0274329.1"
                     /translation="MKITEVIKKDGSKVYRANIYLGVDQVTGKKVKTKVTGRTQKEVK
                     QKATQEKIAFQKAGSTRQKASTIKNYQELANLWLESYKNTVKPNTQDNVRKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKGAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRKKVKHFENQELKKFLGYLDNLDSDRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHVTKTLNRDLEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRESVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(27535..>27906)
                     /locus_tag="VW883_001187"
     CDS             complement(27535..>27906)
                     /locus_tag="VW883_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0274330.1"
                     /translation="TLEYKVDLEFHINTNKPDNLVGIEEIKRNYQQVEIITVKVCLKK
                     QNKETYDKFTKLPSNFQNIFTNDLLQVVGKNIKEYLIQEFKEEFVFAKNSSGHVDQLL
                     SEDIQIIVSSKIVDCKFELPF"
BASE COUNT         8059 a         5284 c         5985 g         8578 t
ORIGIN      
        1 aatctgctat ataatagtcc atgctgtggc tggattcttt tcagcctact tgtactcttc
       61 gaaactctct tcaaaccacg tcagcttcac tttgccgtag gtatggttac tgacttcgtc
      121 agttctatcc acaacctcaa aacagtgttt tgagctgact tcatcagttc tatctgcaac
      181 ctcaaaacag tgttttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat
      241 tgagtattat taagacaata tgaggagaaa gatgaaagaa aaaggatttt aggagggggc
      301 gcaggcagcc atgccaacgg ctcttggcta tgtcagtatc ggcctggcct gtggaattat
      361 cggtgcgccc tatgtgacac ctgttgagat gggcttgatg agtctctttg tttatgctgg
      421 gagtgcccag tttgccatgt tggcactgat tgtggttcaa gctcctgtgg cagctattgc
      481 tatgacggtt tttctaatca acttgcgtct ctttttgttg agtttacacg catcgactta
      541 tttccgtcat accagtcttt ggtacaatat cggtatgtct agtatcttga cagatgagac
      601 ctatggcgtt ttgatgggtg aattggccca tacagacaag gtaaatccta tgtggatgca
      661 cggaaacaat cttaacagct atgtggcttg gtttgtggga acagtggtcg gaacggttct
      721 aggtgacctg ctgccaaatt cagaaatctt tggattggat tttgccctgg ttgggatgtt
      781 catcgggatt tttgcttcgc aatttcagat tatgcaaaga cggattcctg tccgcaatct
      841 gctcattatc ctagcagttg ttgcggtgtc cttctttttg ctcttgacag tggtgtctca
      901 gtcactagct gttctgtttg cgacgctact tggttgtagc atgggggtgg ttttagatgg
      961 tcagtaagta tcttttatta gcagttattt tctctggctt ggtgacttgg attctccgta
     1021 tgattccctt catcttagtc aagtataagg gcttgcctgc aatcgttgag cgttttttga
     1081 agttcttgcc cgtttccatt atctttgcct tgattctttc aagcgtagtg acaggtaagg
     1141 ttgggagtct tcctcaaatt aaatggctag acttcttagc cgtctttcca acagcttggg
     1201 tagcctttcg ctaccgcaat ctagtcggaa cagttctctt tggagtggtc ttgattgcca
     1261 tcttgcgttt ggtcttttaa attacccata aaaaaaactt atcacagaga tagatatcat
     1321 ataatggcgt aaatgctctt tttctgttaa gattataagg tattctattt tggaggaaat
     1381 gacatgaaaa aaatcgttaa atactcatct cttgctgccc taggacttgt tgctgcaggt
     1441 gtgcttgcgg cttgctcagg gggtgctaag aaagaaggag aagcagctag caagaaagaa
     1501 atcatcgttg caaccaatgg atcacccagg ccatttatct atgaagaaaa tggcgaattg
     1561 actggttacg agattgaagt cgttcgcgct atctttaaag attctgacaa atatgatgtc
     1621 aagtttgaaa agacagaatg gtcaggtgtc tttgctggtc ttgacgctga ccgttacaat
     1681 atggctgtca acaatcttag ctacactaaa gaacgtgcgg agaaatacct ctatgccgca
     1741 ccaattgccc aaaatcctaa tgtccttgtc gtgaagaaag atgactctag tatcaagtct
     1801 ctcgatgata tcggtggaaa atcgacggaa gtcgttcaag ccactacatc agctaagcag
     1861 ttagaagcat acaatgctga acacacggac aacccaacta tccttaacta tactaaggca
     1921 gacttccaac aaatcatggt acgtttgagc gatggacaat ttgactacaa gatttttgat
     1981 aaaatcggtg ttgaaacagt gatcaagaac caaggtttgg acaacttgaa agttatcgaa
     2041 cttccaagcg accaacaacc gtacgtttac ccacttcttg ctcaaggtca agatgagttg
     2101 aaatcatttg tagacaaacg catcaaagaa ctttataaag atggaactct tgaaaaattg
     2161 tctaaacaat tcttcggaga cacttatcta ccggcagaag ctgatattaa ataatttctt
     2221 gaaatcatcc attctgagta aggtgggtgg tttctcagtt tttagggata tagttttaaa
     2281 ctatatatct gactatctaa taacaatttg tgaaatcaaa caaattgtga gatactagta
     2341 cggtattatt tttaaggaga aagaatcatg aaaatcaaaa aatggcttgg tctagcagcc
     2401 cttgctacag tcgcaggttt ggctcttgca gcttgcggaa actcagaaaa gaaagcagac
     2461 aatgcaacaa ctatcaaaat cgcaactgtt aaccgtagcg gttctgaaga aaaacgttgg
     2521 gacaaaatcc aagaattggt taaaaaagac ggaattacct tggaatttac agagttcaca
     2581 gactactcac aaccaaacaa agcaactgct gatggcgaag tagatttgaa cgctttccaa
     2641 cactataact tcttgaaaaa ctggaacaaa gaaaacggaa aagaccttgt agcgattgca
     2701 gatacttaca tctctccaat ccgcctttac tcaggtttga atggaagtgc caacaagtac
     2761 actaaagtag aagacatccc agcaaacgga gaaatcgcta taccgaatga cgctacaaac
     2821 gaaagccgtg cgctttattt gcttcaatca gctggcttga ttaaattgga tgtttctgga
     2881 actgctcttg caacagttgc caacatcaaa gaaaatccaa agaacttgaa aatcactgaa
     2941 ttggacgcta gccaaacagc tcgttcattg tcatcagttg acgctgccgt tgtaaacaat
     3001 accttcgtta cagaagcaaa attggactac aagaaagcac ttttcaaaga acaagctgat
     3061 gaaaactcaa aacaatggta caacatcatt gttgcgaaaa aagattggga aacatcacct
     3121 aaggctgatg ctatcaagaa agtaatcgca gcttaccaca cagatgacgt gaaaaaagtt
     3181 atcgaagaaa catcagacgg tttggatcaa ccagtttggt aataagaaac agggaggtgg
     3241 gagagagaat tccacctctt gcttttgtat agagcacgga gtgtaaagaa gactattcgt
     3301 tcatagaaag gtagagagaa tatggttttt cctagcgaac aagaacagat tgaaaaattt
     3361 gaaaaggatc atgtagccca gcattatttt gaggttttgc gtaccttgat ttctaagaaa
     3421 tcagtctttg cccagcaggt tggactcaag gaagtcgcaa attatctggg tgagattttc
     3481 aagcgtgttg gagctgaagt ggagattgat gagagctata cagcgccctt tgtcatggca
     3541 catttcaaga gttcgcgtcc agatgccaag accttgattt tctataacca ctatgacact
     3601 gtgccagcgg atggggatca ggtctggaca gaggatcctt ttacgctttc ggtccgcaat
     3661 ggcttcatgt atgggcgtgg ggttgatgac gacaagggtc atatcacagc tcgcttgagt
     3721 gctttgagaa aatatatgca gcaccatgat gatttacctg tcaatatcag ctttatcatg
     3781 gagggagcgg aggaatcggc ttcaacagac ctagataagt atttggaaaa gcatgcagac
     3841 aaactccgtg gggcggattt gttggtctgg gaacaaggga ccaaaaatgc cttggaacag
     3901 ctggaaattt ctggtggcaa taaggggatt gtgacctttg atgccaaggt aaaaagcgct
     3961 gatgtggata tccactcgag ttatggtggc gttgtggaat cagctccttg gtatctcctc
     4021 caagccttac agtctcttcg tgctgcggat ggccgtatct tggttgaagg cttgtacgaa
     4081 gaagtacaag agcccaatga acgagaaata gccttgctag aaacttatgg tcaacgaaac
     4141 ccagaggaag ttagtcggat ttatggattg gagttgcctc tcttacagga ggatcggatg
     4201 gcctttctaa aacgtttctt tttcgagcca gcgcttaata tcgaaggaat ccagtctggt
     4261 tatcaaggtc agggtgttaa gactatttta cctgcagaag ccagtgccaa gctagaggtt
     4321 cgtctggttc cgggcctaga accgcatgat gttctggaaa aaattcggaa acagctagac
     4381 aaaaatggct ttgataaggt agaattatac tataccttgg gagagatgag ctatcgaagc
     4441 gatatgagcg caccagccat tctcaatgtg atcgagttgg ccaagaaatt ctatccacag
     4501 ggcgtttcag tcttgccgac gacagcgggg acaggaccta tgcatacggt ctttgatgcc
     4561 ctagaggtac caatggttgc attcggtcta ggaaatgcca atagccgaga ccacggtgga
     4621 gatgaaaatg tgcgaatcgc tgattattac acccatatcg aattagtaga ggagctgatt
     4681 agaagctatg agtagagata ttatcaagtt agatcagatc gatgtgactt ttcaccaaaa
     4741 gaagagaacc attacagcgg ttaaggatgt gaccattcac atccaagaag gggatatcta
     4801 cggaatcgtt ggatattctg gagcaggaaa atcaaccctt gtacgggtga ttaacctctt
     4861 gcaaaaacca tctgcaggga aaattaccat tgacgacgat gtgatttttg atggtaaggt
     4921 caccttgacg gcagagcagt tgcgtcgtaa acgtcaagat atcgggatga ttttccagca
     4981 ttttaacctg atgagccaaa agacagcaga ggagaatgta gcctttgccc ttaaacactc
     5041 tggactcagc aaggaagaaa agaaggctaa agtagctaag ttgttggact tggttggttt
     5101 ggcagatcgt gctgaaaact acccttcaca actatctgga gggcaaaaac agcgtgtggc
     5161 aattgcgcgt gccttggcca atgatccaaa aatcttgatt tcagacgagt caacttctgc
     5221 ccttgaccct aagacaacca agcagatttt ggccttgttg caagatttga accaaaaatt
     5281 aggcttgact gttgtcttga ttacgcatga aatgcagatt gtcaaagaca ttgccaaccg
     5341 tgtggcggtt atgcaggatg ggcatttgat tgaagagggt agtgtgcttg aaatcttctc
     5401 aaaccctaaa caacctttga ctcaagactt tatctcaaca gctacaggta ttgacgaagc
     5461 catggtcaaa atcgagaagc aagaaatcgt ggaacacttg tctgaaaaca gtctcttggt
     5521 gcaactcaag tacgctggag cttcaacaga cgagccactt ttgaatgaat tgtacaagca
     5581 ttaccaagta atggctaata ttctctatgg gaatatcgaa attctcgatg gtactcctgt
     5641 tggagaattg gtggtggtct tgtcaggtga aaaagcagcg ttggcaggtg cccaagaagc
     5701 tattcgccaa gcaggtgtac aactaaaagt attgaaggga ggacagtaag atggaatcat
     5761 tgattcaaac ctatttacca aatgtctata aaatgggttg ggctggtcag gcaggctggg
     5821 gaacggctat ctacttaact ctttatatga cagttctttc cttcattatc ggaggcttct
     5881 tggggctagt ggcaggtctc tttctcgtct tgacagcgcc aggtggtgtc ttggagaata
     5941 aagtcgtatt ctggatttta gacaaaatta cctcaatttt tcgtgcggtt ccctttatca
     6001 tcctcttggc aatcttgtca ccactttctc acttgattgt taaaacaagt atcgggccaa
     6061 atgcagccct tgtcccactt tcttttgcag tctttgcctt ctttgcccgt caggtgcagg
     6121 ttgtcttggc tgaattggat ggcggtgtca ttgaggcggc tcaagcgagc ggagcgactt
     6181 tctgggacat cgtgggtgtt tacctatcag aaggtcttcc agatttgatc cgtgtgacga
     6241 ctgtgacctt gatttccctt gttggggaaa cagctatggc cggtgcggtt ggagctggtg
     6301 gtatcggtaa cgtagccatc gcttatggat ttaaccgcta caatcacgat gtgaccatct
     6361 tggcaaccat cgttatcatt ttgattatct ttgcaatcca atccttagga gatttcttga
     6421 ctaagaaatt gagccataaa taaaaaagag ccgtgtggct ctttttaact gatcagattt
     6481 tctgggcaaa ttttttactc aaggcttgtc caatcaaggc acccactagg gctccgatga
     6541 caatacttgc gataaataga aggacagttc cagggtttgg agcgaccatg atacggtcga
     6601 tatattcttg ggattttcct cttgccagaa gagtagccat ataggctttg ggcgcaatcc
     6661 acataagcaa gattggtcct gttgtactaa aggcgaaaat aatgaaagaa aggaagttct
     6721 ttgttttgtc cttgtatttt cctaaatgag ctacttcatc tgctaggagg ccacagataa
     6781 ttccaggaag gaaggaacca gcaccgtgtt tagttcccaa gaaaaagaag gcaatgacaa
     6841 ggccgatagt ggtaatggct ccaaagcgcg gaacttttgc gactaggatc atatagacgc
     6901 taccgccgac aagggcagta aaggcaggcg cataaaacat gtttccagtt tggtcaaaga
     6961 gattgcccaa aaggacacca atccccatgc agaggaagta aagaactgca aaaagcagtg
     7021 tagttaagat agatttcttc atgaattgtc tcctgataat tttttcacaa ttctcatttt
     7081 accatggttt ggtgggattg taaatggata ctagaagttt ttgaaaacgc ttgaaatatg
     7141 atataatggt ttcatagtta tttttagggg aatatcatgg gtagattttt agactttgtc
     7201 tttaatcgtt tctttttagg gatgattgcg acagccttct tttggctatt aactttagca
     7261 ggagggatta tccttggtct agcgccggct agtgccacct tgatgagctt atatgcagaa
     7321 catggttata gctttcggga atacagtttg aaggaggctt ggtctcttta caagcaaaat
     7381 tttgtctcaa gcaacctgat tttctatagc tttttaggtg tgggtctagt tttgacctat
     7441 ggtttgtatc tcttggtgca attgcctcat cagaccattg ttcatttgat tgcgaccctt
     7501 ttgaatgtcc tagtagttgc cctgatcttt ttggcttata cagtatcttt aaaattacaa
     7561 gtttatttta ccttgtccta tcgaaatagt ctcaaattat ccttgattgg catctttatg
     7621 agtctagcag ctgtggctaa ggttctcctt gggactgtgc tacttgtagc aattggttat
     7681 tatatgcctg ccctgctatt ttttgtagga attgggatgt ggcatttctt tatcagtgat
     7741 atgttggaac ctgtctatga aatcatccat gaaaaattgg cgacaaaata gaatgaagca
     7801 gttttggcta catacgcttc taagaaccta tagttcagtg atgatcatta tcattgcgag
     7861 ttttgcaatc ttactctctt acgctgactg ggattcacgt gaaaaggaag cccagagagt
     7921 agcccagcgt gtaactgcta gaacagtgag tgaaattgaa tattaccata gagagtcaac
     7981 ccagatagct caggctttag ttgaaaatca agctcgtatt gagggaatct ataaatactt
     8041 tagccttagc atgccagact atttttactg gcaattagag cggaaagctt cgccttatat
     8101 atcagtctct ctgtatgaaa atgttgatga cctctatgtt cgaaatgatt ttgtaactgg
     8161 agtggccatt gcttttcaag attacaagga agtctatgtt tctactaaag acaaacgtag
     8221 tggagaaaaa atcagggctg aggatttcaa accagcagga aatagttttg ccattccggt
     8281 gtcagatcca gtgtcagatc aagatttagg agtgatttac atctccttgg atcctgctgt
     8341 tttataccat gccattgata atactagagg tcatactccg atggcagtaa cagtgacctc
     8401 accttttgat acggagattt ttcatattgg tgagacagtt gatagggaga gtgaaaattg
     8461 gctagttggc ttaacttctc atggatatca ggttcaggtg gcagttccta aaaactttgt
     8521 tttacaagga acagtgacta gctctgcttt gattgtgggt ttgagccttc tctttattgt
     8581 cattctttat ctgactttga ggcagacttt tgctaattac caaaagcagg tagtggattt
     8641 agtagaatcc attcaagtca ttgctcaagg cgaagagggg cgtcggattg acatttccga
     8701 aaaagatcag gaattactcc taatcgcgga gacgaccaat gatatgttgg atcgattgga
     8761 aaagaatatc catgatattt accagttaga gcttagtcaa aaagatgcca atatgcgagc
     8821 cttgcaggcg caaatcaatc ctcattttat gtataatacg ctggagttct tgcgcatgta
     8881 tgcagttatg cagagtcaag atgagttggc agatatcatt tatgaattca gtagtctctt
     8941 gcgtaacaat atttccgacg aaagagagac cctcctcaaa caggaattag aattttgccg
     9001 taaatacagc tatctctgca tggttcgcta tcccaagtcc attgcctatg gtttcaagat
     9061 agatccagag ttagagaata tgaagattcc caagtttacc ttgcaaccgc tggtagaaaa
     9121 ctatttcgcg catggtgttg accacaggag gacagataat gtgattagca tcaaggctct
     9181 taaacaggat gggtttgtgg aaattttggt ggtcgataat ggtagaggaa tgtcggctga
     9241 aaagttggca aatatccgag aaaaattaag tcagagatat tttgaacacc aagccagcta
     9301 cagtgatcaa aggcagtcta tcgggattgt caatgtacac gagcgttttg tgctctattt
     9361 tggagaccgc tatgccatta cgatagagtc tgcagagcaa gccggtgttc agtatcgtat
     9421 tacaattcaa gatgagtaga aagggagaaa atgtataaag tattattagt agatgatgag
     9481 tacatggtga cagaaggtct gaagcgtttg attccctttg ataagtggga tatggaggtc
     9541 gtcgcaacag ccagtcatgc cgatgaagct ctagaatatg ttcaggaaaa tcctgtcgat
     9601 gtcatcattt ccgatgtcaa tatgccagac aaaacagggc ttgatatgat tcgggagatg
     9661 aaagagatct taccagatgc tgcctatatc ctgctctcag gttatcagga gtttgattat
     9721 gtaaaaagag caatgaacct tagtgtggtg gactatttgg tcaagcctgt tgataaggta
     9781 gagctgggaa atctgctgga gaagattgca ggtcagctcg gcgagagagg gaagaaaagt
     9841 cagactctta gtcaagaatt agacgaggct ggatttgtta gttatttagg ggataaggag
     9901 aattggtgga taggtctatc caaggaaaaa caaggttcct tcaccattcc ctactatgtc
     9961 ttgggccaag actggcagat tttcatttct gaccaacccc tagatggttt agtcgttaca
    10021 ccttttgaag ctccttatca agaacacttt gaacgctgga agctgaatgc tgagaaaacc
    10081 ctcttttacg gttctgtaaa tttgcagcag tctgagagtc tctttgccta ttacgaaccg
    10141 atttataggg ttatcattca gggaaatctc aatcaaatcg tagaagagtt aaatctcttg
    10201 gagaaggtag ttcttgaaaa tacgccgcgt gttccgatta ctaaacagct ttttattcag
    10261 tttgtcatgg atgttttcca tttatttgaa catctcaaag ctgatgacct gacagacatc
    10321 gtcaaaacca ttcatgctat tcaatccttc gatgaattgg ttccttatat caaggaaact
    10381 ctgaccagct ttttcggtca ataccgtatg aatgaaaatg tggtcagtgt gctggaagtc
    10441 attggtcgtg attaccaaaa agagctttcc ctcaaggata tcagtaaggc tctctttatc
    10501 aatcctgtct atctagggca gttgattaag cgtgaaaccg attcgacttt tgcagagtta
    10561 ctaaacaaac aacgtattaa ggctgcccaa caacttttgc tttcaactag tgacagcatc
    10621 gaagatattt gttatgctgt tggttacagt aaccttggat atttctataa agttttccga
    10681 aaattgtgcg gaaaatcgcc aaaagcctac cgaaaacagg tagaaactat actataaaat
    10741 ttgtattcct ttacaaaagg tgctataata ttatcaggag gttctatcat gaaaaagaaa
    10801 ccaatttatc tatgggtctt gctaatcttg tctgccctta tttcagttcc gtctctgttt
    10861 ggaattgtga gtcccttgcc tagtaaagaa gcccttcgtg ctgctcagaa acaagttgca
    10921 ggggtcaatg ctcagcaatt agaagaccag cttaattata cctatagagt agcagaagca
    10981 tctcattcta tttttaatgt tgctttgatt gtgctatcta ctattttagt ggtcgtagcg
    11041 attgtcttcc ttgttcgtaa aaatttgcaa tatgcaaact atacttacgt tggctatgtt
    11101 ttgttagcta ttattggttc gatttatggc tatgttggtt tacaagacgc tgtgcagttg
    11161 gttcaagatg agagcatgcg tttgacagtg agtattggtt caaaagctgt tagcattttc
    11221 tatatcgtca tcaatgttct cttcctagcc cttgtcttct ataagatgtg gcgacaacag
    11281 aaagccttgg cagaagaaga ggaaacagaa gagcttgcct aagtattgac aaaaaagaac
    11341 tatcaagata caatcttggt agttgttttt tgattataga taaaatcatg gaggtacata
    11401 tgaagacaat ttctttagtt tatattagtt tgagtggcaa cactgaaagt tttgtgacgc
    11461 gcttgaaaga ctatctcttg tcccagtaca aagggattga ggttcaaaag attcatatca
    11521 aggatttagt caaggaaggc aaaaatttct atgaaatgga ccatccctat gtcgcttttt
    11581 tgccgaccta tctcgaaggt gggaatggcg tggataacgg agatgttgag attttgacga
    11641 caccggtggg agattttatt gcctatggta acaatgctag taagtgtttt ggtgtggttg
    11701 ggtcaggaaa tcgtaacttt aataaccaat actgcctaac agccaagcaa tacagtcaac
    11761 gctttggctt ccctgtattg gctgactttg aaatgcgagg catgctggaa gatatcaaac
    11821 atgtcgcagc tattatcgca gatttgtatg agttggaaaa ggagaattaa tactcaatga
    11881 aaatcaaaga gcaaactagg aagctagtcg caggttgctc aaagcacagc tttgaggttg
    11941 cagatagagc tgacgtggtt tgaagagatt ctcgaatagt ataaagttct tataagaggt
    12001 ggttgaagtt gttcaactgt tttttgagta taaacagtct ttaagaacgt aaaaaagcat
    12061 aagttcaggt cttcaaaacc ttgttcttat gctttttatc atagaaatat ttgctgaatt
    12121 ttctcttgaa atgaaacctt atcttcatct cgcgcttgtc ccttaccctg cttttccgat
    12181 tgcgagtgcg tagataaaga agatggcgaa gccaaagagg aaaatcaatc ccgcaatggc
    12241 aaggtgtttg agccaagaag gaagattttt gttttcacgc gttaccaagg cgtaattcaa
    12301 aagagcaaag aaaggtgttg tcaggaaaga tccaatcatg gcaaagcgga gcatggttga
    12361 aacctgacca gcgaagaact tgataatgac gataccgatg atagcagtga tggtcatcca
    12421 gatgttcaaa gatttacgat tgtcctcttt ttgactgatt agcagtcgga gagattcctg
    12481 attaacgcga gaatagccat cgataacagt tataactgtt ccaaagatac agaggaaggc
    12541 aataaaggta atcaagtaac gggaccattc gccaagaaca gaggcataca tgcccacgaa
    12601 ttgagagatg tatttggctg aagcagcttc aaccgcctgc cctgtaggat actgaatcag
    12661 tgctcccagt gccacaaaga agacggctag gatagctgtt ccaatataac cagtgttaaa
    12721 gtcaaacaga gcgtcttctg tgttaaagtt gacggtcttt ctcttttcag ctgaccaaag
    12781 tgaattgatg gctgaaattt caataggagc cggcatccat cctaggaggg agacgatgaa
    12841 gggcagagct gccatttgcc aaggtgtctt ctcgacaaaa tcagaactgt attctggatg
    12901 cttgaccgcc gcaatgataa ctgccagaac agtcgcaatg gttaaggcag acataatcca
    12961 tttgaccatg ccgtctaaaa gtttgtagcc tccaaagagt agcatagccc aaatgattgc
    13021 aacgagaatg agggaccact gagtaatgct aagtccaatc attgggaagg cactggcgat
    13081 gatagctgag cacagaatgg caacaccagc cgtgttgacc atagccgaaa agacattgag
    13141 gataaagaaa atccagagat agagttttcc tttttcggca taaccttcaa ccaaagtctt
    13201 tccagtatca gctgtgtatt cagcaccaaa acggaaaaat ggatatttaa agacattggc
    13261 taagatgacc aagagaagta gagaccaacc gtaagaaccg ccagcttgag ttgaggatac
    13321 aatgtgggaa cctccaacag cggcagttgc cattaggatt ccaggtccca ttgcttttag
    13381 cttgcttgcc caggttgatt gatttaagga aatagcttgc gacatgataa atactccttt
    13441 ttgaattttc agaataatct gtatatgtaa tctatattct acaaaaaatt ttggaaaaat
    13501 gcaagagtat tttgaaaaaa gatagaaaat ttacaaagaa gatctgaaat aactattatg
    13561 atatagcgga ttgaaactag aatagtacac ctttgcttct aaaacattgt tagaaatcta
    13621 tttgactgtc ctgatcgatt tatcctgttc ttatttcatt tcactatagt aaggtgcagc
    13681 aggataaaga aaaaccgaga agtttctttc tcggatttgc ttattatgag gttcctattt
    13741 tctatgctcc aagagttgat tgatgtgatc tactttttta gcctctcttt tatagagaat
    13801 agcccagatg atgagataga caatcgcaaa ctcgataatg agctggaggt agaaaatcca
    13861 gtggaaaggg aaccaaccag caagagttgc tagtgggaca aagccagcca gcataaggaa
    13921 gaaatgagtc agagtggcac gaagcatgct ccagtcacgg ctaaataagc ggttgccaaa
    13981 gttgaagagc ataccgatgg ttgcccagat aagtgtgcag tagagcaaga ccagggcacc
    14041 gtgaacctga tgctgatcca tcacttggcc gatgagagag tagggattta gtggtgcgta
    14101 ggtatttggt gcataaatga gtgaaaagag gatagagagg atgaggccga taagaacacc
    14161 ggtagctgca tcgtgaaata cttgtttttt catagttcta atttctcctt gatggttttt
    14221 agataacggc gtgaagagta ggtgaagctt tcgtttttca agaaaatttc taccagaccg
    14281 tttggcgtga gcttgaggtg agagatggaa tcgatattga tgatttctga ttgggaaatt
    14341 tggacaaaat tggttggcaa gagtttaaga acctgataga gtcgcaaatc aatgctgtag
    14401 gtctgactcg cggtttctgc tagaaccttc cgattctcga tatagaagcg ctgaatcttg
    14461 ccaatctcaa ctagatagac ctgatcatcg atttttcctt tgattttttc tctttggtcc
    14521 agattttctg cgaactcgat gactttctgg actttttcgg tttcttgagg tgcttggaca
    14581 atcagctttt cctcctcgta agtctcacta atctgtagtt ctactttcat agttttctct
    14641 ccttttcagt tatacaaggt tgtgatcact tcctgtatat ccttattaaa cactatttta
    14701 tagcccatgg caaggaacct tgtctatgtg gagggattgg gctcctatgt ggtggagctt
    14761 ttctgttctt tctgaaatat ggtataatag cactaatcaa tttctaggaa aatagataca
    14821 gaaaggggct gaaagatgtc tcatattatt gaattgccag agatgctggc aaaccaaatc
    14881 gcggctggag aggtcattga acgtcctgcc agtgtggtca aagagttggt agaaaatgcc
    14941 attgacgcgg gctctagtca gattatcatt gagattgagg aagctggtct caagaaggtt
    15001 caaatcacgg ataacggtca tggaattgcc cacgatgagg tggagttggc cctgcgtcgc
    15061 catgcgacca gtaagataaa aaatcaagca gatctctttc ggattcggac gcttggtttt
    15121 cgtggtgaag ccttgccttc tattgcgtct gttagtgtct tgactctgtt aacggcggtg
    15181 gatggtgcta gtcatggaac caagttagtc gcgcgtgggg gtgaagttga ggaagtcatc
    15241 ccagcgacta gtcctgtggg aaccaaggtt tgtgtggagg atctcttttt caacacgcct
    15301 gcccgtctca agtatatgaa gagccagcaa gcggagttgt ctcatatcat tgatattgtc
    15361 aaccgtctgg gcttggccca tcctgagatt tcttttagct tgattagtga tggcaaggaa
    15421 atgacgcgga cagcagggac tggtcaattg cgccaagcaa tcgcagggat ttacggtttg
    15481 gtcagtgcca agaagatgat tgaaattgag aactctgacc tagatttcga aatttcaggt
    15541 tttgtgtcct tgcctgagtt gactcgggct aaccgcaatt atatcagcct cttcatcaat
    15601 ggccgttata ttaagaactt cctgctcaat cgtgctattt tggatggttt tggaagcaag
    15661 cttatggttg gacgttttcc actggctgtc attcacatcc atatcgaccc ttatctagcg
    15721 gatgtcaatg tgcatccaac taagcaagag gtgcggattt ccaaggaaaa agaactgatg
    15781 actctggttt cagaagctat tgcaaatagt ctcaaggaac aaaccttgat tccagatgcc
    15841 ttggaaaatc ttgccaaatc gaccgtgcgc aatcgtgaga aggtggagca aactattctc
    15901 ccactcaaag aaaatacgct ctactatgag aaaactgagc cgtcaagacc tagtcaaact
    15961 gaagtagctg attatcaggt agaattgact gatgaagggc aggatttgac cctgtttgcc
    16021 aaggaaacct tggaccgatt gaccaagcca gcaaaactgc attttgcaga gagaaagcct
    16081 gctaactacg accagctaga ccatccagag ttagatcttg ctagcatcga taaggcttat
    16141 gacaaactgg agcgagaaga agcatccagc ttcccagagt tggagttttt cggacaaatg
    16201 cacgggactt atctctttgc ccaagggcga gatggacttt acatcataga tcagcacgct
    16261 gctcaggaac gggtcaagta cgaggagtac cgtgaaagca ttggcaatgt tgaccagagc
    16321 cagcagcaac tcctagtgcc ctatatcttt gaatttcctg cggatgatgc cctgcgtctc
    16381 aaggaaagaa tgcctctctt agaggaagtg ggcgtctttc tagcagagta cggagaaaat
    16441 caatttattc tacgtgaaca tcctatttgg atggcagaag aagagattga atcaggcatc
    16501 tatgagatgt gcgacatgct ccttttgacc aaggaagttt ctatcaagaa ataccgagca
    16561 gagctggcta tcatgatgtc ttgcaagcga tctatcaagg ccaatcatcg tattgatgat
    16621 cattcagcta gacaactcct ctatcagctt tctcaatgtg acaatcccta taactgtcct
    16681 cacggacgtc ctgttttggt gcattttacc aagtcggata tggaaaagat gttccgacgt
    16741 attcaggaaa atcacaccag tctccgtgag ttggggaaat attaaaagta taaaaaagtc
    16801 tgggaaaaat tttcaaaatc agaaaaacgc ataaaatcag gtgttcaaaa accttgattt
    16861 tatgcgtttt atcatagaaa tatttacttc attttttcct aattcttttc gaaactcttt
    16921 ttaaacgacg tcagttttat cagtaatctc aaaacagtgt tttgagctaa ttttgccagt
    16981 tttgtctgta acatcgaagt tgtgtttgac cactctgcga ctggtttcct agtttgctct
    17041 atgattttca cagagtatta aattgcgatt ttgccaagtt tctttattcg tctaaaagta
    17101 gagtctgttc tatgcgtcta atgtacgaat taggttgacc atttcaatag ctccttgtgc
    17161 acactcagaa cccttatttc ctgctttagt accagctcgt tctatggctt gttcaattgt
    17221 atctgtcgtt agcacaccaa acataacagg aatttcgcta tttaaactga tttgggcgat
    17281 tcccttagat acctcgctac atacataatc ataatgactt gtattccctc taatgacagc
    17341 tcccaagcag ataattgcat catatttttt actttttgcc atttttgatg caatcagtga
    17401 tatttcaaaa gctcctggaa cccaggctac ctctatatct ttctcgttta cattctctct
    17461 tttgagatta tctagtgctc cagataataa ttttgaagtt ataaattcat taaatctcgc
    17521 tacaacaata cctattttaa tattgtttgc tactaaatta ccttcataag tgttcattta
    17581 tttttcctcc atatttaaaa tgtgacccat tcgatttttc tttgtttcta aataaaaact
    17641 atcgtaagga ttggcttcta tttcgattga tattctactg gaaatagtaa ttccatattt
    17701 ttctaactgt tcaaccttgt caggattatt tgtcagtaaa tgaagtgact gaagtcccag
    17761 atctttaagc atttgtgctc caatatgata ttctcttaaa tcaccttcaa agcctaatgc
    17821 aagattggca tcaagcgtat ccatgccttg atcttgtaaa tgataggctt ttaatttatt
    17881 gataagtcca attcctcgtc cctcctgtcg caagtaaagt aagacacccg aaccattctc
    17941 aacaatcatt ttcatagctt tatcgaattg ctgtccacaa tcgcaacgta aagagcctaa
    18001 aacatcccct gttaaacatt cggagtggat ccgacataat acattggctt catcctctat
    18061 gtttcccata ataagagcaa gatgatgttc cccatttagt ttatctatat agctaattgc
    18121 tttgaaatta ccgtatctag taggcatatt gacagttgaa actcgttcta ccagctgatc
    18181 atatactttt ctatattctt gtaattcttt gatggtaatt agtggaatgt tgtgtttctt
    18241 cgagaactga attaaatcat ctgttctcat cattttgcca tcatgattca ttatttcaca
    18301 acataggcca cactctttta gtccagctaa ttttaataaa tcaacagttg cttctgtgtg
    18361 tccatttctt tctagaacac cacctttttt tgcaattaaa ggaaacatgt gtcctggcct
    18421 gcgaaaatca gagggtgtta tatcttcagc tacacacata cgtgcggtca gtcctctttc
    18481 ctcggcagaa atacctgtgg tcgtttcttt ataatcaatt gaaactgtaa aagcagtctt
    18541 atgattatct gtattgtttt caaccatagg tgaaagcatt aattgattag ctaaactttc
    18601 gctcataggc atacaaatta atcctttggc ataagtagcc ataaaattaa cattttctgt
    18661 tgtagctgct tgtgcagaac aaattaagtc tccttcattt tctctatcct tgtcgtctat
    18721 aacaagaaca agtcgtccct tctgcaatgc ttctaatgtt tcttgtattt ttcgatattc
    18781 cattgactga ttatcctttc tgctaaaatc cattttgata taatagttcc ttagatattt
    18841 ctgattttgg agagttatcc atcagttttt gcacatattt acctaagata tcattttcaa
    18901 gatttactgt actcccgact tgtttacttt taagaatggt ttgtttcaag gtatgaggga
    18961 taacagatac tgaaaagttt actttggaga ctttagcgac agtcagacta atgccgtcaa
    19021 ttgtaataga tcctttttca actattaaat ctaaaatttc tttttgtgtg ttgatttgat
    19081 accatacagc attatcatct ttttttattg acgagatttt tcctgtacca tcaatgtgtc
    19141 ctgtaacgac gtgaccccca agtcgaccgt tgatagataa ggctctttct agattcacct
    19201 cacttccatg ttttaataga gtaagagctg ttcgactcca tgtttcattc attacatcaa
    19261 ctgtaaagga ttgatgattg aaatgagtaa ctgtaagaca gataccattt actgctatac
    19321 tatcgcctaa atggatatcc gttaatattt ttgaggcttt aattgatagt ttacaattac
    19381 gagagtcttt ctgtattctt tcaacttttc cgatttcttc aattattcct gtgaacatgg
    19441 ataaatcact tcactttcta tgagatagtc atttcctatt tgagaaaaag cataaggttt
    19501 caatctaata gcgtcatttg gcaaagaaat gccttcacct ccgacaggaa acttggcact
    19561 gcctccaaaa atttttggtg caatatatat tttcagctca tcaacaattt gttgttccaa
    19621 agcactccaa ttcattagac tgcccccttc tagaactagg ctatcaatct gcatgtttcc
    19681 tagatgttgc attaaactcg ataagtctat atgattgcct tttttcttta tggaaagtat
    19741 ttcacagcca tgattttgat atagcttcat tttatttttg tcttcagagg aagtggcaat
    19801 gtaagtttta atatcatttg ctgtttttac gattttagag gtaagaggag ttcgtaaatg
    19861 tgtatcgcat atgatacgga taggattttt cccttcctcc aatctacatg tcagcaaagg
    19921 atcgtcttga ataacagtat tgactcccac cataattgca ctaacatggt gtcgtaactg
    19981 atgcacatgc tttcttgctt cttcttcagt aatccatttg gattgatttg ttttagtggc
    20041 tatttttcca tccattgaca ttgcatattt cataaaaaca tagggtacat gctgggtaat
    20101 atactttcta aaacttttta ttaagttaag acactcattt tctaaaattc caacagtaac
    20161 ttgaagatta ttttcctcaa gtatctttac tccttttcca gatacaatag gattacagtc
    20221 taggcttcca atgactactc ttgtaatacc actatcgatt atagcatcta tacagggagg
    20281 tgttttcccg aagtgacaac agggttcaag tgttacataa agcgtcgctc cgacagggga
    20341 ttctctacag tttttaagag catttctctc agcatgtggg ccaccaaaaa actcatgata
    20401 accttgtccg atgatgtgat tatcttttac aataactgcg ccgaccatag gattgggatt
    20461 gacgtaacca gccccttttt gtgccagttt tattgctaat ttcatatatt ttgaatcgct
    20521 catctcacta cctccaaaaa aaatatacct tgaatagggg actactcaag gcatacaaaa
    20581 gaaaacttat gcgattaaca aaaatactct gaaatgacaa gtaatcattt cagagcacgc
    20641 aaaaagcaca aatatacttt tatcttcttt catccagact atactgtcgg ctttggaatt
    20701 tcaccaaatc atgcctttcg gctcgtgggc tataccaccg gtagggaatt acaccctgcc
    20761 ctgaagatag ttattcaatt acagatgatt atagtactta attttgaata tgtcaacaga
    20821 taaataccga ttgtttttga tatactgtat ttgtgataat cgattctcgc tcctcggata
    20881 aagaaaatat gatatactag ataaacgaaa taagagagaa ggaatactat gtacgcatat
    20941 ttaaaaggaa tcattaccaa aattactgcc aaatacattg ttcttgaaac caatggtatt
    21001 ggttatatcc tgcatgtggc caatccttat gcctattcag gtcaggttaa tcaggaggat
    21061 cagatttatg tgcatcaggt tgtgcgtgag gacgcccatt tgctttatgg atttcgctca
    21121 gaggatgaga aaaagctctt tcttagtctg atttcggtct ctgggattgg tcctgtatca
    21181 gctcttgcta ttatcgctgc tgatgacaat gctggcttgg ttcaagccat tgaaaccaag
    21241 aacatcacct acttgaccaa gttccctaaa attggcaaga aaacagccca gcagatggtg
    21301 ctggacttgg aaggcaaggt agtagttgca ggagatgacc ttcctgccaa ggtcgcagtg
    21361 caagcaagtg ctgaaaacca agaattggaa gaagctatgg aagccatgtt ggctctgggc
    21421 tacaaggcaa cagagctcaa gaaaatcaag aaattctttg aaggaacgac agatacagct
    21481 gagaactata tcaagtcggc ccttaaaatg ttggtcaaat aggagcagag aatgacaaaa
    21541 cgttgttcgt gggtcaagat gaccaacccg ctctacatcg cctatcatga tgaggagtgg
    21601 ggtcagcccc tccatgatga ccaagcattg tttgagttgt tgtgtatgga aacctatcag
    21661 gcaggcctgt cttgggaaac ggtactcaac aaacgccaag ctttccgaga agcctttcat
    21721 agctatcaaa ttcactcagt cgcagagatg actgagactg aattggaagc catgctggag
    21781 aatccagcta tcattcgaaa tagagccaag ctttttgcta cacgcgctaa cgcccaagcc
    21841 tttctacagt tacaggcaga gtacggctct tttgatgcct atctttggtc ttttgttgag
    21901 gggaaaactg tcgttaacga tgttcctgat tatcgccaag ccccagctaa aacaccctta
    21961 tctgagaaat tagccaaaga tctcaaaaaa cgaggcttca agttcacagg cccagtcgcc
    22021 gtattgtctt ttctacaggc tgcagggcta gttgatgacc acgagaatga ttgtgagtgg
    22081 aaaggtctta aatgatgtct aacaaaaata aggaaattct gatttttgcg attctctata
    22141 cagtcctctt tgtgtttgat ggcgttaaat tgctggcttc tttaatgcca tctgccattg
    22201 caaattatct tgtttatgta gttttagctc tatatggctc cttcttgttc aaggatagat
    22261 tgatccaaca atggaaggag attagaaaga ctaaaagaaa attcttcttt ggcgtcttaa
    22321 caggatggct ctttctcatt ctgatgactg ttgtctttga atttgtatca gagatgttga
    22381 agcagtttgt gggactagat ggacaaggtc taaatcagtc taatattcaa agtacctttc
    22441 aagaacaacc actactgata gctgtttttg cttgtgtcat tggacctctg gtagaagaat
    22501 tatttttccg tcaggtctta ttgcattact tgcaggaacg gttgccaggt ttactaagca
    22561 ttattctggt aggacttgtt tttgctttga ctcatatgca cagtttggct ctatcagagt
    22621 ggattggtgc agttggttac ttaggtggag gccttgcctt ttctattatt tatgtgaaag
    22681 aaaaagagaa tatctactat cccctacttg ttcacatgtt aagcaacagc ctctccttaa
    22741 tcattttagc tatcagtata gtaaaatgaa atgagaacag gacaaatcga tttctaacaa
    22801 tgttttagaa gtagaggtgc actattctag tttcaatata ctgtaatatg tgatgaaaat
    22861 gccagtaatg ataccgagaa aaaagctgag aaacttttcc cagctttatt tgttatagtc
    22921 aaagagaatg acttgttcct gtgcatctac atgagcatgg accccaaagg gtacaattgc
    22981 tcttggagtt gcgtggccga cattcagatt atagacaatc gggatattgc tgtcaatgat
    23041 atccaatagt gcctctttat agtcgtcatg gaaagtttca tccataggtt ttccgaccaa
    23101 gagtccattg atgaccgcga atatgccagt gtcctttaaa gttagcaaca tctttttgaa
    23161 gtcttctgac ttaggctttt cttcgcttgt ttcgagcaag aggattttcc cttcccagtc
    23221 tgacaagtca gggaaaagtt tgtatttttg gcagagttcc gtgctatctg cgtatcgaga
    23281 gttgtcaaag atatcgtaga gggattcgag gcaaccaccg aggattttcc cctcgaactg
    23341 ggcccttcct tgcaacaagt caaaacctgt atttgtatga ctgacacgag gtgttcccag
    23401 ggccgtggga ctaaaatcag ttcgttcctc ataccaaacg tcactagggc ggatttctga
    23461 aattcttccc gtctcaatca attctttaaa gtagtgaagg ctataggcta gcatttcttt
    23521 gtctaattca caaatgtctg ctaaaaagga ttgaccataa aaagtcttga ttcctaattt
    23581 atgcaacatg aggtggttca tggttgtatc cgagaagcca agaaaaattt tttgtttgat
    23641 aaccttttgg agttggtcat tttcaaaaag ataaggtagc aagcgatagg tatcgtctcc
    23701 accgatggca cataggatca tgtcgatgct atcatcagaa aaggcatgaa tcaaatcctc
    23761 tgcacgagct tcaggatggt ccttgataaa gtctaatcct tttaacgaat ggggcaaaaa
    23821 gatgggattg agtcccagat ccttgagacg ttggataccc aagtccactt cgtgtttgac
    23881 aaaatcctct ccgataatgc cactagataa actaacaata ccaatagtag aaaccatatc
    23941 tcatcctcct agaaatagat tgagcctatt ttatcacaaa atataagaga aagctatgtg
    24001 ggatttcaga agaatacttt taatactctt cgaaaatctc ttcaaaccac gtcagtttta
    24061 tctgcaacct caaagctgtg ctttgagcaa cctgcagcta gcttcctagt ttgctctttg
    24121 attttcattg aatataactc aaaaaagtaa gtgaaaaagc aaccgcacct gcagttgctt
    24181 ttatcgtttt cttattcttg atagcgtgtt ggtcctgcac ttgcactacg gatattcaag
    24241 cgtttcttga gatagaagcg aagggctagg agggctgctc caataatagc tagtggcaat
    24301 ggatccagta ctgggttaag gctagctggt aggaagcttg ttgcaaagaa gacaagcaac
    24361 caaaggaaca tagaagctag gataactagt acagatttcc agaaaggtgg acgttgactg
    24421 cgatccatat ctggtccata gtattggtaa acaaagtagt acatcaagta gaaggcaaat
    24481 ccaccaacca gtccaactaa tagaagagta atcaatccat agccgaaagc ttggtctgcc
    24541 gcaaagaagg ttgtgagggc gctgacaagg gcaaagaggc tagtgatgaa aagagctgag
    24601 tccataatca tcagttttgg gtcatcattt tcttttggat gctctttttc gtactgctct
    24661 ttgacagtga agctatgagc ccaatgagtt ggtgcgccgt atagggaacg ggcagttgta
    24721 cctttagatt gctcctcaag gatttgggga atgacttcct caaaaatagt ctggatttca
    24781 gcgtctgttt tcccatcttt gatgaattgt tgggtagcaa tgtggacaaa ctcttggttt
    24841 ttcttagtta atttttgtag atcaatttga gacataggaa ctcctcttag aaccattttt
    24901 tatggatgag atagagagtg agcgagacac tcatagcaaa ggcgataaag acgattaacc
    24961 agaaggcatt tggctctccg tttaggggga tttcattatc cttaaagttc atcccgtagg
    25021 cagaaaagac catggttggg atggacatga cgatggtcac aagggccaag gttttcatga
    25081 tgttgttctg gttgttagaa atgatagagg caaaggtctc tgtcatagaa tgcaagacgt
    25141 ttccataaat atctgccatc tcgatggcct gttgggtttc aatcagggtg tcttcaagca
    25201 ggtcttcgtc ctcaaggtat ttcttgatat tgctggttga actggtcaat ttcttaatca
    25261 cgcgctcatt tgttttgagg gaggccttga aatagacgat agttttttcc aattccatga
    25321 gctcaatcaa ttcttcatta cgagttgatt gatgcagttg actttcgatt tgttcactct
    25381 tgcggtcgat tgaacgaagg gctgttaggt aaagctctgc attgcgataa agaatttgaa
    25441 agataaaacg tgaacgcatg aaggtataga aattacgcaa tcgacggttg ataaagacat
    25501 caaggacagg tagtggttcc aaacacgtag tgataatggt ttcctcagtg atgataatac
    25561 caagcgggat ggttacgtag taggtgcggt tatttctttc ctccgtgacc ggcacgtcta
    25621 cgataatcag ggtatactcg tcttcaatgg taatacgaga catttcttcc gcatcgagcg
    25681 gtgctcgaag gtcggcaata tcaatatcga aggtgttggc gatttcgagt gattcatttt
    25741 gagtcggatt gacgagattg atccaagtac ccggttcaag cgtatcgatc tctttaaatt
    25801 cagttgttgt agagagaaaa acttgtttca tatcccttat cccttatcct ttctcatttt
    25861 tcagattttt tcacactgta ctattatact acaaaatcgg cctttttcaa aataaatcta
    25921 acaaaaaacc tgttgctatt ggatttttgc tttgtcttga aatgttgatt tttaaatttg
    25981 ctccccctat agtgctttta gtgcagtttc gtagaatgat actgcttttt ttgcgttctc
    26041 ttttgagagg tggctgtata tatccatggt cattgataaa gtggaatgac ctaggcggta
    26101 ctggagttct ttgtatggta ttccagagtt aagcaagaga ctagcgtgag tgtgacggaa
    26161 tccgtgaaag ccaatgttag gaacgtcagc acgcttaaaa tgtgtttgca atcttctttt
    26221 aagtcttgaa ctgctaggat actcatgaat gaagtcagaa aatactacac tttcacgttg
    26281 ccctatcttc caagcctctt tagtttggcg tagtttgtac tgcttcagca tgctaacagt
    26341 cgcttgatct atatctatat cccgataact agccttagat tttgggctat taatttctaa
    26401 atcacgattt agtgttttgg taacatgtac cacggcatta tctaaatcta tatcagacca
    26461 ggaaagagct aaagcttcat tgatacggca accagtagcc aataggaact tatagagcgt
    26521 tgtctcatag tagtaacgat atctatcgct atctaaatta tcgagataac caagaaactt
    26581 ttttagttct tgattttcaa agtgttttac ttttttccgc tttgctttct gagtgttacg
    26641 aggtaaaaca acatcacggg caggattgga cggtatagcc tgcatagtta cgccatactg
    26701 taagatacgt ttgtttagag cgtgtatctt gtcataatgt agaaaagccc ctttttcccc
    26761 tctattagtc ttgtcagcaa gttcgttgat aattgactgg ataagtggag tagtgagttt
    26821 atcgagctta taagccccaa aaataggcaa tatatgatta tcaattaact ttctaacatt
    26881 gtcttgagtg tttggcttaa ccgtattctt ataactttct aaccagagat tggctaattc
    26941 ttgatagttt tttatggtgc tagccttttg tctagtagat cctgcttttt gaaaagctat
    27001 tttttcttga gtagctttct gcttaacttc cttttgtgtc cgtcccgtta ccttagtttt
    27061 aactttcttt cctgtaacct ggtcaactcc tagatatata ttagcacgat agactttact
    27121 accgtctttt tttataactt cagttatttt catgatttaa acctttctaa aatacatcag
    27181 caggcaagcc attatcaaaa aggttttata tcatgctagg tcttcacaga ttgccctgta
    27241 ttcgatttta attagtcagg cggtaaataa taccaaagtt tgaaacaagg cggatatggg
    27301 gcttatatgg gcttgaagct cgaacgaagc ttgagaaatc acgcgcagaa cgtgaaaaaa
    27361 catgaatttt ttgaagattt caaaagctag aaaaaccagt acttacaagt ctttcaatgg
    27421 ttttaagtta tttgggttca tgttgacaaa agttgacatt ttcagagtat aacataccaa
    27481 aaaactagga aaacttatat ttcagttttt caagatagta acaaatgaaa atttttaaaa
    27541 aggtaactca aatttgcaat caacaatttt tgaactaaca ataatttgaa tatcttcgct
    27601 taaaagctgg tcaacatgtc ctgaagaatt ttttgcaaaa acaaactctt ctttgaattc
    27661 ttgtattaaa tactctttta tatttttacc aactacttga agtaaatcgt ttgtaaaaat
    27721 attttggaaa ttgctaggta atttagtgaa tttatcataa gtttctttgt tttgtttctt
    27781 caaacaaact ttcactgtga taatttctac ttgctgatag ttacgcttaa tttcctcaat
    27841 accaacaaga ttatctggct tattagtgtt tatatgaaat tcaaggtcca ctttatactc
    27901 tagtgt
//
LOCUS       DAVKXA010000026        27881 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKXA010000026 DAVKXA010000000
VERSION     DAVKXA010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.026"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            114..836
                     /locus_tag="VW883_001188"
     CDS             114..836
                     /locus_tag="VW883_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0274331.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1054..2388
                     /gene="pepC"
                     /locus_tag="VW883_001189"
     CDS             1054..2388
                     /gene="pepC"
                     /locus_tag="VW883_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0274332.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2444..3355)
                     /locus_tag="VW883_001190"
     CDS             complement(2444..3355)
                     /locus_tag="VW883_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0274333.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3379..4182)
                     /locus_tag="VW883_001191"
     CDS             complement(3379..4182)
                     /locus_tag="VW883_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0274334.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4210..5199)
                     /gene="manX"
                     /locus_tag="VW883_001192"
     CDS             complement(4210..5199)
                     /gene="manX"
                     /locus_tag="VW883_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0274335.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5432..6451)
                     /gene="adhP"
                     /locus_tag="VW883_001193"
     CDS             complement(5432..6451)
                     /gene="adhP"
                     /locus_tag="VW883_001193"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0274336.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWAVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(6790..7602)
                     /locus_tag="VW883_001194"
     CDS             complement(6790..7602)
                     /locus_tag="VW883_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0274337.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7792..9210
                     /locus_tag="VW883_001195"
     CDS             7792..9210
                     /locus_tag="VW883_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0274338.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            9263..9970
                     /locus_tag="VW883_001196"
     CDS             9263..9970
                     /locus_tag="VW883_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0274339.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            10065..11039
                     /gene="folP"
                     /locus_tag="VW883_001197"
     CDS             10065..11039
                     /gene="folP"
                     /locus_tag="VW883_001197"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0274340.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALATGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            11041..12363
                     /locus_tag="VW883_001198"
     CDS             11041..12363
                     /locus_tag="VW883_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0274341.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            12344..12898
                     /gene="folE"
                     /locus_tag="VW883_001199"
     CDS             12344..12898
                     /gene="folE"
                     /locus_tag="VW883_001199"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0274342.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            12941..13753
                     /gene="folK"
                     /locus_tag="VW883_001200"
     CDS             12941..13753
                     /gene="folK"
                     /locus_tag="VW883_001200"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0274343.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(13798..14115)
                     /locus_tag="VW883_001201"
     CDS             complement(13798..14115)
                     /locus_tag="VW883_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0274344.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            14472..14918
                     /gene="rplM"
                     /locus_tag="VW883_001202"
     CDS             14472..14918
                     /gene="rplM"
                     /locus_tag="VW883_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0274345.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            14937..15329
                     /gene="rpsI"
                     /locus_tag="VW883_001203"
     CDS             14937..15329
                     /gene="rpsI"
                     /locus_tag="VW883_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0274346.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(15617..16771)
                     /locus_tag="VW883_001204"
     CDS             complement(15617..16771)
                     /locus_tag="VW883_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0274347.1"
                     /translation="MSIHKYKTKKGVLYYVSFYIGLDAYGKKKRHLKRGFKTKKEAKL
                     YEARLEAGVVAPTVNTDKPNPKVTYKEFYQEWFKAYVGTVEETTSSQTKNIYRIHILP
                     IFGGKFIDQISPLDCQNFITQKSQTFKNIKQIKSYTSKIFDFAINMNYIDRNPMKNVI
                     MPKIKKTRSDNFWSLEELHHFLDIVKETEPFKHFALFRLLAFSGLRKGELYALKWADI
                     NFDSNLLNIDKSLGRIDGKAIEKSTKNESSVRTIYLDDETIDIIKQWRNFYLKEQSQF
                     PLTKLNISNEYMFYYISSNDKIEPLHADYINNVLNRIIKKHKLKPISPHGFRHTHATL
                     MSEIGIDPSNTSKRLGHASSQMTLDVYTHTTKTGEKNSIDKFADYLNKAK"
     gene            complement(16823..17341)
                     /locus_tag="VW883_001205"
     CDS             complement(16823..17341)
                     /locus_tag="VW883_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0274348.1"
                     /translation="MSNHITKLIEDSGKKLTEISEATDIAYPTLSGYNQGIRKPKKDN
                     AEKLAKYFNVSVAYIMGLDSNPHAPSNLKIVTDSFKTSKIGSVTPFKSDMEKLKKSIE
                     FGERALTLPLDDSFSDEFRHIFSEYLAEKNKRFMSEFIDYMNHQNKDSKVWQSWIKTD
                     EYAIRQEDRKNR"
     gene            17489..17770
                     /locus_tag="VW883_001206"
     CDS             17489..17770
                     /locus_tag="VW883_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0274349.1"
                     /translation="MSETTLVVQLPKELEKQLRAHYDEMISNAVARVFEDKELYKPMV
                     RMSGLSRWLDVSTTTIQKWTKEGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            17779..18618
                     /locus_tag="VW883_001207"
     CDS             17779..18618
                     /locus_tag="VW883_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0274350.1"
                     /translation="MNGVQWIKITTDIFDDEKIQLIESMPEGDTLIVIWFKLLVLAGK
                     QNNSGILSLGNKVYYTEEMLSTVFRRKATSVKLALSMFEEFGMIEIIDGAITIPKWEK
                     HQNIDGLEKIRKQTRERVARHRQKQKALIKGEPQLILDCNVTVTDENENVTQEIKNES
                     KNKKEIENILDNSSRKPETYIPPKYYSLLESISYKYNDRFLYPNNYTLTHAQKMKIGE
                     YLASGYVTSDEVISMIERIPEDAASPLAYLFKSMENLKQERMLECKTIAHENARKKYM
                     INE"
     gene            18611..18970
                     /locus_tag="VW883_001208"
     CDS             18611..18970
                     /locus_tag="VW883_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274351.1"
                     /translation="MSRYRTILKKFYITEEQNEIANNLIKMTNHLSFSSYARKMLFKR
                     SPIYLQFDFKSYHDFIFQVRRIINNLRQLERIAKQSEDLDNVRIFHCCVEMMIGYEKK
                     TSKQVKELVKRLNKKTR"
     gene            18978..19310
                     /locus_tag="VW883_001209"
     CDS             18978..19310
                     /locus_tag="VW883_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274352.1"
                     /translation="MRIKSVLKQVFLTEEENKKLNDCMRKENICNFSEFARKKLIRTD
                     LNIHKVSFEGLVPLTEELEQVGKNINSIARLATVVGRISYENKMDMSIMMQKIVDVME
                     EKDVYFQK"
     gene            19291..19485
                     /locus_tag="VW883_001210"
     CDS             19291..19485
                     /locus_tag="VW883_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274353.1"
                     /translation="MFIFKSSMDKDFDQICEYILKLKRAELFLHGIKQQDKTKARLYH
                     AMLEYYDANHKKVRHMRILK"
     gene            complement(19876..20172)
                     /locus_tag="VW883_001211"
                     /pseudo
     CDS             complement(19876..20172)
                     /locus_tag="VW883_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            20580..21248
                     /locus_tag="VW883_001212"
     CDS             20580..21248
                     /locus_tag="VW883_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001158457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HEV0274354.1"
                     /translation="MQETMIDYKQKIYQELSRLTKGLGSEKRLDILNILSQGPKTVEG
                     IAHTTGLSVANTSRHLQILKESHLVVTSRNGNFIRYSLASEKVVQLVLLLFAVGEEQL
                     AEVRAIESDYDEAAGVPQIELANAIELAAKTDALLLDLRPVEEYEAGHLPKALNLPID
                     EFDQKKAQLPKEKTIIVYCRGRQCGYANLAAQDLQSLGYSIYSLNRSFADWKWGASSR
                     SELD"
     gene            21554..21868
                     /gene="trxA"
                     /locus_tag="VW883_001213"
     CDS             21554..21868
                     /gene="trxA"
                     /locus_tag="VW883_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0274355.1"
                     /translation="MTTQLTTETFAKAIQDGVSLIDFGAQWCPPCRMMEPVVEELSKD
                     FDGKATIAQVDVDQSQDLANLFGIRSIPTMVIFKDGKPVDALVGVHPKQTLMEKIQAQ
                     LS"
     gene            21877..22797
                     /gene="trxB"
                     /locus_tag="VW883_001214"
     CDS             21877..22797
                     /gene="trxB"
                     /locus_tag="VW883_001214"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0274356.1"
                     /translation="MYDTIIVGSGPAGYTAGIYLSRAGLKNRLITGYSEGGQLTTTTL
                     VENYPGFENGIEGNKLVQTMRRQAEQFGTEMTFGFVQKIEGESSPFKVHLDNGEIIDT
                     KAVIIATGSSAKYLGIEGEEEAVGKGVSACATCDAFFYKEREVLVVGGGDVAMEEALY
                     LTRFASKVTVVHRRNELRASDIMVKRAQANDKIHWMLNYTPVKVASNLMGMTGLDVRN
                     NETGDIEHIQADGLFVAIGHQPNTDFLDGKLALDDKGYIQTQAGTAKTSVAGIFAAGD
                     VQDPKYQQAITAAGSGAIAALDTLAYIDNL"
     gene            22794..23063
                     /locus_tag="VW883_001215"
     CDS             22794..23063
                     /locus_tag="VW883_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274357.1"
                     /translation="MMDSVTSSIELEELLDEHQNLALLVSGNQCSLSSLGQKELIDTA
                     EREHLVLYQADIFQVPRLISLFGIQPTLTSLLVFKKGQLVDRKEV"
     gene            23064..23243
                     /locus_tag="VW883_001216"
     CDS             23064..23243
                     /locus_tag="VW883_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003156488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEV0274358.1"
                     /translation="MARKALIQRKKKAYPVQEYSRCLACGRPHSVYRKFKLCRICLRQ
                     QAYQGVIPGLKKASW"
     gene            23267..23917
                     /locus_tag="VW883_001217"
     CDS             23267..23917
                     /locus_tag="VW883_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family oxidoreductase"
                     /protein_id="HEV0274359.1"
                     /translation="MEISYWSDIACPFCYIGASRMKRAMAAVGLNPEDLTMKAYQLNP
                     NAPLETSETMLTEFATSHGMTTEQVKAQFAHMESMGNEEGLRIDMAGIIPTNTFSAHR
                     LIKWSQKYLDKKDHQNFITALYYLYFEEHANIADHSVLLAVISEFDLPQEEAAQVLAG
                     DAFADEVKRDILEAHQSGVQGAPFFVLNNKYGISGAQPYEYMLATLKKIQAEEGAQ"
     gene            23919..24095
                     /locus_tag="VW883_001218"
     CDS             23919..24095
                     /locus_tag="VW883_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274360.1"
                     /translation="MIDTPFQLLDSNSEETGLVCGIDGCSIDPSTQPLENTYQPLEKS
                     KKAVIGRTEWKNKE"
     gene            24077..24640
                     /locus_tag="VW883_001219"
     CDS             24077..24640
                     /locus_tag="VW883_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEV0274361.1"
                     /translation="MEKQRVEALSDAILAIIVTIMALELQLPEELTVAGLRSMLPMLF
                     IYITSFLQIMAVWLYYHELYKLVDHVSFHLFGANSFWLLTASFVPLATRGIGQNSANF
                     AFLLFYLIVLALWDVSWIIMTAMVIKTSQRQLSAEEKKIPYRWALLYGLQLVIILLVG
                     YLFPNFIPFAPLLMIINVIYGFLSNKS"
     gene            complement(24790..25008)
                     /locus_tag="VW883_001220"
                     /pseudo
     CDS             complement(24790..25008)
                     /locus_tag="VW883_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25189..26655
                     /locus_tag="VW883_001221"
     CDS             25189..26655
                     /locus_tag="VW883_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274362.1"
                     /translation="MFSKLSDHDFKKGVFRTKFSQLVTPLGKESDWAHSKGPEYLWIG
                     LALQYGNRIEQMERVMLALTNLSKALDLEKILPLPAMSLILNLDIDEKKIFVESLNSA
                     FDLSIFSPLSIILPDSEEVLSKNFYSKSHSFNQRLDILVKVLNEVSDQYSQLSTDVRY
                     FLLYYKMLQGKIQFVESQLHMVDGLSKYPYLDISDPEMRIIRPQIRSMEVALSMSEDM
                     NYPYSKRFWNNISQLTDCEVYSIVMDRSNTIDLNKIKDTVFSTLKYYRDMLQSIEPFN
                     EKLYVLTSILTYSYKRLLELMNHGLQYTISGRSIVRSCIENYVMTKYLIAEEEKHKNI
                     WEEYQYYGIGGYKLISERYIENQPELTNSHINFEYLNLLVSEFQNKEFIDMDTRYFGK
                     GNIRQKFEQVEEDDLYKYHYDYDSQFEHGLWGAIRESSILKCNSAGHQFHGIPDIDDI
                     QKLPDVSHDLVMVLTKHLSVIKEVFPIPSEQIEGDSLC"
     gene            26649..27719
                     /locus_tag="VW883_001222"
     CDS             26649..27719
                     /locus_tag="VW883_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274363.1"
                     /translation="MLDRLRQSQNEYLELLKRVRWDLDLENVAYHLDKIRNFWFRKQK
                     LLEMCSQYLFNNSNTYFYTAVSKFNVDNSDKNIIFALGNYQIFDDPILSYLEVMEKGN
                     TVHQIERYFKKLKEKIVESIDDLIVLLEKEIPNFYVLPLRFSSSTINKEKVDIRPFIE
                     NFFIEGIDFNNLHKYENIDTVVVHEYLSQILLFDYDDPTQAIKDRLKQYRIEYSDIVP
                     QDMNDTELFQFIVYGYFSQAMDIFLTSYSFNISPFFSSLTTYINYNVFLLNIVHNSKK
                     EKLEHFLKMSRLTLPIWFEYDKKGVELSISEIRERAKNINFSDRIREIYNALDDFNTK
                     EQLITEVENCVHLLINYEGRGC"
BASE COUNT         8598 a         4960 c         5834 g         8489 t
ORIGIN      
        1 tggatgtttc cttttaaacg aagtatattt atactatacc ataaaattga taatagttca
       61 cctaataaaa tgttagttat gtacaacaat aatttccatg atataatagt tctatgagat
      121 tagataaatt tttagttgcc tgtgcggtgg gaagtcggac tgaggtcaaa aacttgctca
      181 aggctgggcg cgtgactgta aatggtaaaa aagaaaaatc agctaaattg cagattgatg
      241 aaaaaataga tgagattcgc tttgatgggc aagtgttgga gtatgaagag tttgtctact
      301 acatgatgaa caagcccaaa ggagttatct cagcgactga ggatcccaag cacagaaccg
      361 ttctggactt gttggatgac ttggcgcgga gtaaggaagt tttcccagta ggacgcttgg
      421 atattgacac gcatggtctt ttgctcttga ccaatgatgg tcagctggct catgttcttc
      481 tttcgcccaa gcgtcatgtg gacaagactt atctggcaca agtcaaggga atcatgaccc
      541 aagaagatgt ggagacattt gctgagggta ttcctctcaa agactttacc tgtcaacccg
      601 ctatactgga gcttgtatcc atagatacag aaaagaatca aagccaaatc cgtgtgacca
      661 ttgcagaagg gaagtttcat cagatcaagc gtatggtggg ctactgtggc aaggaagtgg
      721 tggacttgca acgattgact atgggaactt tagtattaga tgagaacctg gaacgagggg
      781 aatggcgtcg cttgaccaag gaagaattag aaattctccg cgctaatatt atttaattta
      841 gtttaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg ctgtacttga
      901 gtacggcaag gcgacgttga cgtggtttga atttgatttt cattgagtat aaattcgaaa
      961 aaggtgaggg acaatgtcct cgccttttat gttttttagt tgcttccttt gtgaaaagag
     1021 ttataataga ctgtagaata aaaggaggaa tctatgaacg cgattcaaga atcatttact
     1081 gataaactat ttgccaacta tgaagcaaat gtaaaatacc aagcgattga aaatgctgcc
     1141 agccacaacg gaatttttgc agctctggaa cgtcgccaaa gccgtgtaga caacacacct
     1201 gttttctcat tggatttaac caaggacaag gtcactaacc agaaagcgtc tggtcgttgc
     1261 tggatgtttg cggctctcaa caccttccgc cacaaactca tctcgcaata caaattggag
     1321 aactttgagt tgtcacaagc ccacactttc ttctgggata agtatgagaa atcaaactgg
     1381 ttcttggagc aagtcattgc gacttcagac caagaattga ctagccgcaa ggttagcttc
     1441 ttactccaaa cacctcaaca agatggcggt caatgggata tggtcgtttc cctctttgaa
     1501 aaatacggtg tcgtgcctaa gtcagtttat cctgagtctg tttcatctag cagcagtcgt
     1561 gagctaaatg cgatccttaa taaattgctt cgtcaagatg ctcaaatctt gcgtgacttg
     1621 cttgtttctg gtgcagatca agcgactgtt caagctaaga aagaagacct cttgcaagaa
     1681 atctttaact ttcttgctat gtcattagga cttccaccac gcaagtttga ctttgcttat
     1741 cgcgataaag ataacaacta caaaagtgaa aaaggaatca caccacaaga gttttacaag
     1801 aaatatgtca atcttccttt agaagactac gtttctgtta tcaatgctcc aactgctgat
     1861 aaaccttacg gaaaatctta cacagttgag atgttgggga atgttgttgg tagccgtgca
     1921 gttcgctaca tcaacgttcc aatggagcgc ttgaaagaat tggcgattgc ccaaatgcaa
     1981 gcaggtgaga ctgtttggtt tggttctgat gtcggccagc tcagcaaccg taaggctgga
     2041 atccttgcga cagatgttta tgactttgaa tcaagcatgg acattaaact tactcaagac
     2101 aaggctggac gtttggacta tagcgaaagc ttgatgaccc acgccatggt cttgacaggt
     2161 gttgacttgg acgaaaatgg taaatcaacc aagtggaagg ttgaaaactc atggggagac
     2221 aaggtcggta cagatggtta ctttgttgcc tcagacgctt ggatggacga atacacatac
     2281 caaatcgttg ttcgtaagga attgctgaca gcagaagaac aagctgccta tggagcagaa
     2341 ccaatcgtac ttgcaccatg ggatccaatg ggagccttgg ctgaataaaa gcatagaaaa
     2401 aaggaatcag attttagaac ctggttcctt tttagttgct tgattacatg atgtgaagaa
     2461 catgtgccac aatacccact gcgaagaggg caaggataat agtgattgga gatacttttt
     2521 tcttaagtaa gtacatgcaa agtaaagtaa ggagtagtcc tgataatcca ggaatcaaca
     2581 tatccaagtt ttgttggaaa gtagtaactt tttcaggagt ttgagacaat ccttgtccta
     2641 cttgtgcgaa tgcttcttgg atacctttag acccttctgg caatttatcc caatggatat
     2701 aagccttttc atctagttga actttagaaa catcgaaagc aaatttaata tttacccaac
     2761 gttgaacaag gacagcaaga atgaacatcc caaggataga agctccttta gtgatatctt
     2821 gaaggatacc accagacata tctttagtga tttctgatcc agccttgtat ccaatctctt
     2881 gaacatacca caagaatgac atacgaatca agttccatgc aacaaagaag aggagtggcc
     2941 ccaagatatt gccagtaagg gcaagtgaag caccgagaga tccaaggatt gggcgtactg
     3001 taaaccagaa tactgggtca ccgataccag caagaggtcc catcataccg attttgaccc
     3061 cttggatagc agcgtcatcg atttccacac cgttagcacg ttcttcttca agcgcaagag
     3121 taacccccat gactggagca gctacgtatg gatgagtgtt gaagaactca aggtgacgct
     3181 caagagcagc gatttgatct tcttttttag tatagagttt tttgatagct ggaatgagtg
     3241 tataagccca gcccaagttt tgcatccgtt caaagttcca agacccttgt aagaaggttg
     3301 aacgccacca aactttttta cgatctgatt tagttaattg aagtttttca gtcatgatgt
     3361 tttcagtcct ttcttatctt agtagtcttc taggatatcg ccgattgggt cgttagaagt
     3421 tgcggctcct ccgccaccat ttccaccagt tttagaaagg tgaaggtaga taagagcgat
     3481 agcaacaccg atagcaccga atccgattag agtaatatct gacacagcag cgagaacgaa
     3541 accaagagcg aagaatggcc atacttcacg agttgccatc atgttgataa ccatggcgta
     3601 accaacggca acgaccatac caccaccgat agccatacca tctttgagcc agtctggcat
     3661 ggcactaagg atactttgta cagtttcagt tggtaccata aggagaagag ctgcaggaag
     3721 cgcgatacga agtccttgga agagtagcgc aatgaaatgc gcacgctcca cagcgccgaa
     3781 gtcacctttt ttagcggcag catctgcagt atgaaccaaa ccaactgaaa ttgtacgaac
     3841 aatcattgtc aagaaaagtc cagctacggc aagagggata gcaaccgctt gggcaacacc
     3901 gataccagtc ttggtaaagt caccaccaag aaccatgata atggcagcag cgacagaagc
     3961 aagtgcagca tcaggagcga tagcagcacc gatatttgac caaccaaggg caatcatttg
     4021 aagcgatcca ccgaggataa tccctgcttc caagtgacct gttacaagcc caataagggt
     4081 acaggctaca agtggttggt gaaattggaa ctggtcgagg atgccttcaa gacctgcaaa
     4141 gaaggctaca acgactacta aaaccataga aataatagac atgtttaaaa tcctttcata
     4201 aataatggct tatttgacat tggctttgtt aatcaagtca aacaaatctt ttttagaatc
     4261 atttggtact ttacggacat caaattcaac acccaagtca cgcatttttt caaatgtcgc
     4321 aacatcttct ttgtccatag acaaaacggt attgaccaat gttttacctg ttgagtgagc
     4381 catagaacca acgttaagag tcttgattgg cacgccgcct tcgatggcac gaagggcatc
     4441 ttgaggtgtt tcaaacaaga taagggcatg tgtttctcca aaacgtgggt cttttgaaat
     4501 ctcaatcagt ttttgaattg gaaccacgtt agccttgaca ttacctggag ctgcttgttt
     4561 aatcaattct ttacgaaggt cgtctttagc cacattatct gaagcaacga tgatacgatt
     4621 tgcttttgaa tctggagtcc aagcagttgc aacctgaccg tgaagtagac gtgtgtcaag
     4681 acgggcaaga ttgattttca atttaccgtc tccgataaca gttccttctg ggatagcagt
     4741 ttgggcaact ggagcagctg cagcgcttgc aacttcttca actggattta gctcttctgg
     4801 aagagctttg atgccatctt tggcttcttt aatgatatta gcagcgactt tttctacacc
     4861 tgcagcagcg tccatgaggc gctctgtgta ggcttgaatc aacatcggta agttaagtcc
     4921 tgtgatgatg gcaaacttac gctcaggatt ttctcccatc acgcgactag cttggttaaa
     4981 tggagaacca ctccaaaggt cagccaaaac tagaacctca tcttctgcgt caaatgcagc
     5041 aacagcgtta ttaaacttag cgtatagatc atcaggacct tcatttggca taaaggtcac
     5101 aacttgaacc ttttcttgtt caccaaagat catagatcct gactgatgaa tacccgcagc
     5161 aaattcgccg tggctcgcaa taatgattcc gatactcatt attgtcattc ctcctttttt
     5221 gttttagttt tcatttaaga aaactttaag actgtttaag tataaaccgt tttcataaaa
     5281 aaagcaacta tttatcataa aaaattaaaa aatttttatt tttgtatgtt gatatgttga
     5341 gtttttgagg agtaatcttg aattcttatt taaaatttaa tataaaaaag ttggaagaag
     5401 cttccaactt ttaaaatagg tttctattag attagtgggt gaagtcgagt accatacgtc
     5461 cttggatttg gcctttttcc atttcgtcga aaatggcaac agcatcttct actggacgtt
     5521 tttgaacaac tgggactacc agaccttctg caccaaattg gaaggcttct tctaagtctt
     5581 tacgagttcc gacaagagaa ccgatgactt ggattccatc gaggactgtt ttaacgatgc
     5641 tgagttccat catttcagaa ggaagaccaa cagcgacgac gcgaccacca gcacgaatgg
     5701 agtcaacagc ctggttgaag gcaactttag acacagcagt tacgacagct gaatgagctc
     5761 ctccatcagt tttttcttta atgagtccag ctacatcttc aacttcgagg ccgttaatca
     5821 caatgtcagc gcctacttct tttgcaaggg caagtttgtc attgttgata tcgactgcga
     5881 taacatgagc attgaatact tttttagcgt attgaacagc gaggttacca agtccaccag
     5941 caccgtaaag aacagcccat tggcctggtt caacttttgc ttctttgata gctttatagg
     6001 ttgttactcc agcacatgtg atagaagaag cttgggctgg atcaagtccg tcaggaactt
     6061 tgacagcata gtcagcagtt acgatacatt gttcagccat accaccgtct actgagtagc
     6121 cagcattttt cactgtacgg caaagggttt cgcgaccagt tgtacagtat tcgcaagtgc
     6181 cacatccttc aaagaaccaa gcaacgctga cgcggtcacc gactttaagg cttttcacat
     6241 ctggagcaat ctctttaacg ataccgatac cttcgtgccc aagaacacgt cctgggactt
     6301 gaccaaagtc accatgagca acgtggaggt cggtgtggca aacgccacag tattcaactt
     6361 ctacaagtgc ttccccagtt tcaagtggac ggagtacttt ttcttcaata gcaacaccag
     6421 tgctttctgg atttacaaca acagctttca tagctatcct ccttgatatt gaccgagaac
     6481 agggacaacg ggactggatt gattttttgt caacagagtc gagtgtgacg agctctcttg
     6541 tatttatatg tgaagtatat cacaaaagaa agccttttcc aaggttttgg agacaaaaag
     6601 tagaacaatc gattaactgg ttgatgagac tgtgaaaaga gcacaaagac cagcttgcaa
     6661 gctggtcata ctcttcgaaa atctcttcaa accacgtcag cttcatctac aacctcaaag
     6721 cagtgctttg agcaacctac ggctagcttc ctagtttgct ctttgattct cattgagtat
     6781 cagtataggt tataagaata agtcttgtag ggttttggca accccatctt ggtcgttggt
     6841 aagggaaatt tgctcatctg cataagggag tagctctgga ttggcatttt tcatggcata
     6901 acccttccca gcaaaagcga gcatttcggt atcattgtgt tcatctccaa aggcaatcaa
     6961 atcttttttg tcacgattca ttatcttgag caagtagtcc aaagcaaagg ccttgttgac
     7021 accttttggg gtacattcaa ggatattgag cggacctccc caggtattga tagaaagttg
     7081 atgctggtag aaggcgttca tttcttttgc caaggcatat ttgtcactgg ctctggtctg
     7141 caagaggata cagttagggt ccttggtcac caattcaggc tggaattgat cttcaggctg
     7201 gaaagcttct acaccaaata gtttgggatt ggcaatttct tcattgggat ttgtaatgta
     7261 gaatttttta cgatattctc cagcgataaa atcggcttga atgtcctctg aacgttgaac
     7321 catatctagc agatattttt tgtctacagt caaacacttt tcaaaatccc aaacttggtc
     7381 tggtaaatga gtaagggatc cgttgaagtt aatcatagga gtgtctaagc ccagttcacg
     7441 gtaaaaatct tttgacatac ggtaagggcg acctgtcgta ataataacct gatggccttt
     7501 ttcagcaact tttttgatgg tttttttggt aaagtcagaa atttgactgt ctgagttgag
     7561 cagggttcca tctaggtcaa ctgcaataat ttttttcgtc atatggacct ttctagtgtg
     7621 ttttcagata agatgtcttc tattataaca gaaagcaggc agaaaagcag attccaaaca
     7681 aaaaatgaaa ttggattaat ttcttaaaca aatcaaacaa agacattgaa aaagtgaatg
     7741 ataaatgata taattctatt attgttcgta aaaattaaaa ggagattgat gatggacaaa
     7801 ttatttaaac taaaagagaa cggtacagac gttcgtacag aggttctcgc tggtttaaca
     7861 actttctttg caatgagcta tattctcttt gtaaacccac aaattctttc gcaaacagga
     7921 atgcctgctc agggtgtgtt tcttgcaacg attatcggtg cagttgctgg taccttgatg
     7981 atggccttct atgctaactt gccatacgct caagcaccag gtatgggact caatgccttc
     8041 tttaccttta cagtcgtatt tggacttggt tattcatggc aagaagccct agctatggtc
     8101 ttcatctgtg ggattatttc attggttatt accttgacaa atgttcgtaa aatgatcatt
     8161 gaatcgattc caaatgccct tcgctcggct atttcagctg gtatcggtgt cttccttgcc
     8221 tatgtaggga ttaagaatgc tggacttttg aaatttacga ttgatccagg caactatact
     8281 gttgtaggag aaggggctga caaagctcaa gcaacgattg cagcaaactc ttcagcagtt
     8341 ccaggcttgg tcagctttaa taatccagct gttttagtgg ctcttgcagg acttgccatt
     8401 actatcttct ttgtcatcaa agggattaaa gggggaatta ttctctctat cttgacaaca
     8461 actgttcttg ctattgcagt tggtttggtt gatttgtcta gtatcgattt tgctaataac
     8521 catgttggtg cagcttttga agatttgaag acaatctttg gtgcagctct tggttcagaa
     8581 ggtttgggag ctttggtttc agatacagct cgcttgcctg aaactctgat ggccattctt
     8641 gccttctcat tgacagatat ttttgacaca attggtacct tgatcggtac aggtgaaaaa
     8701 gttggtattg tagcgacaaa tggtgaaaat caccaatcag ccaaattgga taaggctctt
     8761 tactctgatt tgattggaac gacagtcggt gccattgcag gtacttcaaa cgtaacgact
     8821 tatgttgagt ctgctgctgg tatcggtgca ggtggacgta ctggtttgac agccttggtt
     8881 gtagctatct gttttgcgat ttcaagcttc tttagcccac ttctagcgat cgtaccaaca
     8941 gcggctacag ctccaatctt gattatcgtt gggattatga tgcttggtag cttgaaaaat
     9001 atccattggg atgatatgtc tgaagcagtt cctgccttct tcacatctat ctttatggga
     9061 ttcagctact ctatcactca agggattgca gttggtttct tgacttacac tttgactaag
     9121 cttgtcaaag gtcaagttaa agatgttcat gccatgattt ggattttgga tgccttgttt
     9181 atccttaact acatcagcat ggccttataa tagaatgacc cagggggatt tccccccttt
     9241 tttaatacaa aggagatagg tgatgaaaga gaaaaatatg tggaaagaat tgttgaatcg
     9301 tgcaggctgg attttggtct ttttacttgc cgtcctttta tatcaggttc ccctagtggt
     9361 tacctctatt ttgactttaa aagaagtagc cctgctacag tcagggctga tagttactgg
     9421 cctttcaatt gtggttctgg ctctatttat tatgggagct cgtaaaacca agttagctag
     9481 ttttaatttt tcttttttta gagctaaaga tttggcacgt ttgggcttga gttatttagt
     9541 tattgtcggg tcaaatatac ttggttctat cttgttgcaa ctgtcaaatg agacgacaac
     9601 agctaaccag tctcagatta acgatatggt tcagaatagt tctctgattt ctagcttctt
     9661 cttgctagcc ttgcttgctc caatttgtga ggaaatcttg tgccgtggga ttgttcctaa
     9721 aaagattttc cgaggcaagg agaacttggg atttgtagtc ggtacgattg tgtttgcttt
     9781 attgcatcaa ccaagtaatt taccttcttt attgatttat ggaggtatgt cgacagttct
     9841 atcttggacg gcctacaaga cccaacgttt ggaaatgtcg atcttgcttc acatgattgt
     9901 taatgggatt gctttctgtt tgttggctct tgtggtgatt atgagtcgga cattaggaat
     9961 ttctgtttaa aagtttttat gtaggaaccg acctctttct actagggaaa gatgaatgca
    10021 atcgtgtcca tctttttctt tttatggtaa aatagaaaaa taatatgatg aaaatccttg
    10081 agggagtgac cgatatgtca agtaaagcca atcatgcaaa gacagttatt tgcggaatta
    10141 tcaatgtaac cccagactcc ttttcggacg gtggtcaatt ttttgctctt gagcaggcac
    10201 tccagcaggc tcgtaaattg atagcagaag gagccagtat gctcgatatc ggcggagaat
    10261 cgactcggcc gggaagtagc tatgttgaga tagaagagga aatccagcgt gttgttccag
    10321 tgatcaaagc gattcgcaag gaaagtgatg tcctcatctc tattgatact tggaagagtc
    10381 aagtagcaga ggctgctttg gctactggtg ccgatctagt caatgatatc actggtctca
    10441 tgggtgatga aaaaatggcc catgtggttg ctaaagctgg agcgaaagtg gtcatcatgt
    10501 ttaacccagt tatggctcga cctcagcatc ctagttcgct tatcttccct cattttggct
    10561 ttggtcaaac ctttacagaa aaagagttag ctgactttga aacattgcca atcgaagact
    10621 tgatggtggc tttctttgaa cgagcactag cgagagcggc agaagctggt attgcaccag
    10681 aaaatatcct gttggatcca ggaattggct ttggtctgac caagaaagaa aatcttctcc
    10741 ttttacggga cctggataaa ctacatcaga agggctatcc aatctttctc ggagtgtcgc
    10801 gcaagcgatt tgtcatcaat atccttgaag aaagtgggtt tgaagtcaat cctgagacag
    10861 agcttggttt ccgaaatcgg gacacggctt cggctcatgt aactagtatc gctgcgagac
    10921 agggtgtaga agtggtgcgc gtgcatgacg tagctagtca caggatggca gttgaaattg
    10981 cctctgccat tcgtctggct gatgaagcgg aaaatttaga tttaaaacaa tataaataag
    11041 atgaaagaaa ttgaaaacaa tcagtggatt gctaactacc ggacggatca accgcatttt
    11101 ggcttggaac gaatggtgga actgttagct ttgcgtggca atccccatct taaactcaag
    11161 gttctccata tcggagggac taacggcaag ggctcgacta ttgctttttt gaaaaagatg
    11221 ctagaaaagc tagggctgag agttggcgtg tttagttcgc cctatctcat tcattacaca
    11281 gaccagatta gcatcaatgg ggaatcgatc tcagaagcga ggctagaagc tctcatggca
    11341 gactatcagt ctttgctgga gggagaagcg gtcgccaatt tacagggcac aaccgagttt
    11401 gagattatca cagccctagc ctatgactac tttgcctcag agcaagtaga tgtggctatc
    11461 atggaagttg gcatgggtgg acttttggat agtaccaatg tctgtcagcc cattttgaca
    11521 ggaattacaa ctattggctt ggatcatgtg gccctacttg gtgacacctt ggaggccata
    11581 gcagagcaga aggcaggtat tatcaaacaa gggatgccct tggtaacagg gcgtattgct
    11641 ccagaagcct tgactgtgat tgaccgcatt gcggaaggga aagatgcgcc gagacttgcc
    11701 tacgggacag attatcaggt tcgtcatcaa gaaagtgtgg tgacagggga agtctttgac
    11761 tatacaagtg ctgtcagaca aggtcgcttc cagactagcc tgcttggttt gtaccaaata
    11821 gagaatgctg ggatggccat agctttactt gatacttttt gtcaagaaga tggtcgagag
    11881 ctagcaagca atgactttct tggtcaagcc ttggaagaaa caagttggcc agggcgtttg
    11941 gaaatcgtgt caagagatcc cttgatgatt ttggatggag cccataatcc ccatgctatc
    12001 aaggccttgt tggtaacctt gcaagaacgt tttgcggatt atcataagga aatcctcttc
    12061 acttgtatca aaaccaaagc cttgggggat atgttggact tgctgggagc catgccagat
    12121 accgagctta ctctaacaca ttttgcggat agtcgggcga cggatgaaag cgtgctgaaa
    12181 gaggcagcta agtctagaaa tctcagctac caagattggc atgattttct agagcagaat
    12241 ttgacagata aaaaagaaga gaaacaaaca gttaggattg tcacaggttc cttgtatttc
    12301 ttgagccaag tgagggccta tctgatggag aggaagaacg agaatggata cacaaaagat
    12361 tgaagcagct gtaaaaatga ttatcgaggc tgtaggagag aacgctaatc gcgagggctt
    12421 gcaggaaaca cctgctcgtg tagcccgtat gtatcaagag attttttcag gtcttggtca
    12481 aacagcagag gaacatttgt caaaatcctt tgaaattatt gacgataata tggtggtaga
    12541 aaaggatatc tttttccata ccatgtgtga acaccacttc ttgccatttt atggtagagc
    12601 gcacattgcc tacattccag atggtcgtgt ggcaggcttg tctaagctag cccgtacggt
    12661 tgaagtttat tcgaaaaaac cacaaattca agaacgtttg aatatcgaag tggccgatgc
    12721 cttgatggac tatctaggtg ctaaaggagc ctttgttgtc attgaggcgg aacatatgtg
    12781 tatgagtatg cgtggtgtta gaaaaccagg cactgcaacc ttgacgacag tagctcgtgg
    12841 tctatttgaa acagataagg acctccgcga ccaagcttat cgtttaatgg ggctataaaa
    12901 agaatccgtt tcaagcggat ttttctagaa aggaatcatt atggatcaac tgcagattaa
    12961 ggatttggaa atgtttgcct atcatggtct ttttcctagt gagaaagaat tggggcagaa
    13021 atttgtcgtt tcagccatcc tatcctatga tatgaccaag gcagctacag acttggattt
    13081 aacagcctct gtccattacg gagaattgtg tcagcagtgg acgacttggt ttcaggaaac
    13141 gagtgaagat ttgattgaaa cggtagccta taaactggtg gaacgtacct ttgagtctta
    13201 tcctcttgtc caagaaatga agttggaact gaaaaaacct tgggcaccgg tgcatttgtc
    13261 actagatact tgctcggtaa ccattcatcg ccgcaagcaa cgagccttta tcgccctagg
    13321 aagcaatatg ggagataaac aagcaaactt gaagcaagcc attgacaaac tgcgagctcg
    13381 tggcatctat attctcaaag agtccagtgt cttagcgacg gagccttggg gtggagtgga
    13441 gcaggatagc tttgccaatc aagtggttga ggtggaaacc tggctaccag cacaagactt
    13501 gttagaaacc ttgttagcca ttgagtcaga gctgggacgg gtgagagaag tgcattgggg
    13561 acctcgtttg attgatttgg acttgctctt tgtggaggac cagatccttt atacagacga
    13621 cctcatattg cctcatcctt acatagcgga acgccttttt gtccttgagt ccttacagga
    13681 aattgcgcct cattttatcc atccgatatt aaaacaaccg atccgtaact tgtatgatgc
    13741 tttgaaaaaa tagaaaaact ctagttttca gttacttgca actgaaggct agagttttta
    13801 aaataggtca ttttcttctg ggaggaggat agtttctcta ccgtccatgt ctaaaaccag
    13861 tactcttggg ggataacgag ggtcgaaagg atggttaaag tcaaaatcaa tggctgtagg
    13921 gaggtgttga cttgaaaagt ggaaggtaat ctttccttgg ttattaagca attgaaactc
    13981 gagttcttct tccaattcaa agacattttt taagaaatgg tcgataatat accaaaaaga
    14041 gtcaatgatg tcatcaggca agctggtaac aatgccaaaa ctagcagacc gcatgtgggt
    14101 attggtaaaa gccatatctc tgtctccttt cttttccctt atcatacagc aaataggatt
    14161 aaaaatcaag aaaaggtgat tttttgaaaa ggattttaac tacagggaaa aagaaggaaa
    14221 aaaattccca aaaatctacc gaagttaata ggtaaattcc caaattaact tgattatata
    14281 actttcagtt attttgagaa gttaccgaaa aatatttttt atatctattg acttttaggg
    14341 gtgaaatttg gtatgatagt aggcggtatt gtttacccca tttgaaaggc cccggaacct
    14401 tccaaatact tttcgatggg aaggaacacc catcaccgta aacaaaaatc gaactatata
    14461 taggagaaat catgaacaaa acaacattta tggctaaacc aggccaagtt gaacgtaaat
    14521 ggtacgtagt tgacgcaact gatgtaccac ttggacgtct ttctgcagta gttgctagcg
    14581 tacttcgcgg aaaaaacaaa ccaacattta caccacacac tgatacaggt gacttcgtga
    14641 ttgttatcaa tgctgaaaaa gttaaattga ctggtaaaaa agcaactgat aaaatctact
    14701 acactcactc aaaccaccca ggtggattga aacaaatctc tgcaggtgaa cttcgttcta
    14761 aaaatgcagt acgtttgatt gagaaatcag ttaaaggtat gcttccacac aatacacttg
    14821 gacgcgctca aggtatgaag ttgaaagtat ttgttggagc tgagcacact cacgctgcac
    14881 aacaaccaga agttcttgac atttcaggac ttatctaagg aaaggaacaa taaagtatgt
    14941 cacaagcaca atatgcaggt actggacgtc gtaaaaacgc tgttgcacgc gttcgccttg
    15001 ttccaggaac tggtaaaatc actgttaaca aaaaagatgt tgaagagtac atcccacacg
    15061 ctgaccttcg tcttgtcatc aaccaaccat tcgcagttac ttcaactgta ggttcatacg
    15121 acgttttcgt taacgttata ggtggtggat acgctggtca atcaggagct atccgtcacg
    15181 gtatcgctcg tgcccttctt caagtagacc cagacttccg cgattcattg aaacgcgcag
    15241 gacttcttac acgtgactca cgtaaagttg aacgtaagaa accaggtctt aagaaagctc
    15301 gtaaagcatc acaatttagt aaacgttaat tcgaaagaat tactatactt atacagagca
    15361 cctttcgggg tgttcttttt ttatactttc ttactaaatt ggtgcaattg acacagttgt
    15421 tgcgacttta gtcgcttaca aatgtggctg caacctgaca aggtcagttg cctcaaaacg
    15481 ttaatcaata cgattatatc aacgtttcaa agcactttgc aaagattttg caaagtgctt
    15541 ttttgtcgat ttttgagctc gaatagcttt gtgataacct tctgataacc tcttttagat
    15601 tttaaacatc atgattttac tttgctttat tgagataatc tgcaaatttg tcaatagagt
    15661 ttttctcacc agtttttgtg gtgtgagtat agacatctaa tgtcatctga ctgcttgcgt
    15721 gaccgagtcg ttttgatgta ttagaaggat cgattccaat ttcagacata agtgttgcat
    15781 gtgtgtgtct gaacccatgt gggctaattg gttttaattt atgcttttta ataattcgat
    15841 tcagtacgtt attaatgtaa tcagcatgca aaggttcaat tttgtcatta cttgatatgt
    15901 aatagaacat atattcgtta ctaatattca actttgtaag aggaaactga gattgttctt
    15961 tcagatagaa atttctccat tgcttaataa tatcgattgt ctcatcatca agatagattg
    16021 tacgaactga agattcattc tttgtgctct tttcaatcgc tttaccgtca attcttccta
    16081 gacttttatc tatgttcaat agattgctgt caaagttaat atcagcccat tttaaagcgt
    16141 ataactcccc ttttcgtagt ccactaaatg caagcagtct aaataaagca aaatgtttaa
    16201 atggctcagt ttctttcact atatcaagga aatgatgtaa ttcctccaga gaccaaaaat
    16261 tatctgatct agtttttttg attttaggca tgataacatt cttcattgga tttcgatcaa
    16321 tgtagttcat gttgattgca aaatcaaaaa tttttgaggt ataggatttt atctgtttga
    16381 tatttttgaa agtctgagat ttttgtgtaa taaagttttg acagtctaaa ggactgattt
    16441 ggtcaataaa tttaccgcca aatattggta gaatatgtat tcgatagata ttcttagttt
    16501 gggaagaagt tgtttcttca acggtaccaa catatgcctt aaaccattct tgataaaatt
    16561 ctttataagt aactttggga ttaggtttgt cggtatttac tgtaggggcg acgacaccag
    16621 cttctaaacg agcttcgtac aattttgcct cttttttggt tttgaatcct ctctttaagt
    16681 gccttttttt ctttccataa gcatctaagc caatgtaaaa gctgacatag taaaggactc
    16741 ctttttttgt tttgtatttg tgtatagaca ttttttctcc gtatctaagt tttcggagct
    16801 tatgtaatcg agaaatgagt gtctatctat tttttctatc ttcttggcgg atagcgtatt
    16861 cgtctgtttt aatccagctc tgccaaactt tagaatcttt attttggtga ttcatatagt
    16921 ctataaactc agacataaaa cgtttgtttt tctcagctag gtattctgag aatatatgac
    16981 gaaattcatc tgaaaaacta tcatcaagtg gtagtgttaa tgccctttcg ccaaattcga
    17041 tacttttctt taacttctcc atatcgcttt taaaaggtgt cacagaacca attttagatg
    17101 ttttgaaact atctgtaaca attttaagat ttgatggagc gtgtgggttg ctatcaagtc
    17161 ccataatata agcaacggaa acattaaagt attttgctaa tttttcagca ttatcttttt
    17221 taggtttgcg gatcccctga ttgtatccag aaagtgtagg ataggctata tctgtagctt
    17281 cgctaatttc tgtcaatttt tttccgctat cttctattag tttagtaata tgattgctca
    17341 tgagaacctc ctttttatca ttataacaca ttttattctt tttgaataaa aaagcttgac
    17401 aaaaattcaa aaagaatata taattcaaaa tgaataacaa attaaatggt ttcggagctt
    17461 atttaattta gaaatgaggt gttaatttat gtcggaaact actttagttg tccagcttcc
    17521 taaagaatta gagaagcaat tacgtgctca ttatgatgag atgatttcaa atgctgtggc
    17581 aagagtattt gaagataaag aactttataa acccatggtt cgtatgtcag gtttgtctag
    17641 gtggttagat gtatctacga cgacaatcca aaaatggaca aaagaaggaa tgccaaccat
    17701 ggtaattgat ggagtgactt tatacgataa aagagcagta acaagatggt tgaagcaata
    17761 tgaaagatag gtacttgtat gaatggtgtt cagtggatca agataacaac agatatattt
    17821 gatgatgaaa aaattcagct aatagaatcg atgccagaag gagatactct tattgtaata
    17881 tggtttaaac ttctggtgct tgcaggaaag caaaataata gtggaatatt gagtctagga
    17941 aataaggtat attacacaga agagatgctt tcaacagtgt ttagacgaaa agctacatcg
    18001 gtaaaattag ctctcagcat gtttgaagaa tttggcatga tagaaatcat agatggcgct
    18061 attaccattc caaaatggga gaaacatcag aatatagatg gcctagaaaa gattagaaaa
    18121 caaacaaggg aacgtgttgc tcgccataga caaaaacaaa aagcactaat taaaggcgag
    18181 ccacaactca ttttagactg taacgttaca gtaacggatg aaaatgagaa tgtaacgcaa
    18241 gagattaaga acgagagtaa gaataagaaa gagattgaga atatactgga taatagttct
    18301 agaaagcctg aaacttatat tccacctaaa tattattctt tgttagaatc catttcttat
    18361 aaatacaatg atagattttt gtatcctaac aattacactt taacacatgc tcagaagatg
    18421 aagataggtg agtatttagc tagtggatat gtaactagtg atgaagtcat tagcatgatt
    18481 gaacggattc ctgaggatgc agcttctcct ttggcgtatt tatttaagtc tatggaaaat
    18541 ttaaagcagg aacggatgtt ggagtgcaaa acaattgctc atgaaaatgc cagaaagaag
    18601 tatatgataa atgagtagat atcggactat tctaaagaaa ttttatatta ctgaagaaca
    18661 aaatgaaata gcgaataact taattaaaat gacaaaccat ctaagttttt cctcttatgc
    18721 tagaaaaatg ttgtttaaac gttcgcctat ttatcttcaa tttgatttta aatcttatca
    18781 tgactttata tttcaagtaa gaaggattat caataactta cgtcagttag aaagaatagc
    18841 gaaacaaagt gaagatttag ataatgtaag gatatttcac tgctgtgttg agatgatgat
    18901 aggatatgaa aagaagacaa gcaaacaagt gaaagaactt gtgaaacgac taaataagaa
    18961 aacgaggtga taaaattatg agaataaaat cggtgttgaa acaggtattt ttgacagaag
    19021 aagaaaataa aaaattaaat gattgtatga ggaaggaaaa tatttgtaat ttttctgagt
    19081 ttgctagaaa aaaattaatc cgaacagatt tgaacattca caaagtctct tttgaaggtt
    19141 tagttccttt aacagaagag ttggaacagg taggaaagaa tatcaattct atagcccgtc
    19201 ttgcaactgt agttgggaga ataagctatg aaaataaaat ggatatgtct attatgatgc
    19261 aaaaaatagt tgacgtgatg gaggaaaaag atgtttattt tcaaaagtag tatggataag
    19321 gattttgatc agatatgcga atacatattg aaattaaagc gagcagaatt atttcttcat
    19381 gggattaaac aacaagataa aacgaaggct cgtttgtatc atgcgatgct ggaatattac
    19441 gatgctaacc ataaaaaagt aagacatatg agaattttaa aataaggaaa cgctgttaaa
    19501 aatttgcagc gttttttata tatcttctta aaatatttgt acacacaaat gacagtcaaa
    19561 ttgatttttg ggattatttt atcgagaagg aaagatttat cataatatga ctttgcgagc
    19621 tcagagtctg tatacacata gtgtatgtac tttttgggat gatttgaatt ttggggaatc
    19681 cccaaacccc tgatgaatta tacgagcaaa aaaatttggg agtaagtttt agaaagaact
    19741 attctacagt atttaaaatc tgactttaag taaatttttt attatgtgac tattagtctg
    19801 tctcactccg ctaggtgcga gacaaaaaaa cacccgctat gcgggatgct ttttctgttc
    19861 accccaaaat tcaccttatt gttttagaga ctttaaagca aattcgccta ctgtcatagg
    19921 aactacatta gaagtattta cataaatctg tgttgttcct gtgtcactgt gtgttagagc
    19981 ctcagaaata gcttctaagt tcattcctgc ttgtttagca gtatgtcgca gttcatgagg
    20041 tgtagcatgt gccagctctt tatgttgctt tctgatactt ttcattttat tgtttagata
    20101 gtcagcatgt aaaggcttat tgatgtttcc tctagtgtct atataagtaa agacaaaccg
    20161 tccagatagt atgtcttgca tgctgtttac ttcttgtctc ttgttttagg ttttgagata
    20221 atagcgacaa cagaagtagt tgtggactat ttttatgaat gtttaaatta atcattagaa
    20281 aattgttggc agttgagagc tctaagtaaa tcattttgat acaatttatg gtcgcacata
    20341 gatagtatgt cacaaaagaa actgcggctc gttaaaaatt tcattttttc agagataggt
    20401 ctctttttac atgatttacc tattaatatt agtaaatgtt aaagataagt attcttttta
    20461 ttttttggcg aatgccggcc tttttgccac aaatgagtat caacatcttt cgaatggaat
    20521 agttgacaac tggttttaag aattatacta ttgaattgaa tagataagga gttgatttga
    20581 tgcaagagac aatgattgat tacaaacaaa aaatttacca agagctatct cgcttaacaa
    20641 aggggctagg aagtgagaag cgtcttgata ttttaaacat attatcacag ggaccaaaga
    20701 cagttgaggg aattgcgcat acgacgggtc tctctgttgc caatacttcg cgccaccttc
    20761 agattttaaa agaaagtcac ttggtggtga cgagtcgaaa tggtaatttt atccgttata
    20821 gcttggcttc tgaaaaggtt gtccagttag tccttctgtt atttgccgtc ggtgaagaac
    20881 agttagcaga agtcagagcg attgagtcag actatgatga ggcagctggt gttcctcaga
    20941 ttgagctcgc taatgcaatt gaattagcag ctaagacaga tgctctccta cttgatttaa
    21001 ggcctgttga ggagtatgag gcagggcact tgccaaaagc tcttaattta ccaatcgatg
    21061 agtttgatca aaaaaaagct cagcttccca aagagaagac catcattgtt tattgtcgcg
    21121 ggcgccaatg tggctatgct aacctagcag cacaggattt acagagtttg ggctacagta
    21181 tctatagtct caatcgcagt tttgctgatt ggaagtgggg cgcatcctct cgttcagaac
    21241 ttgactaagg tgaattcctt agtcttttct tataaccgga gactcgtgag caaaatcatt
    21301 gtaaaataga tttagtatgc tataattcaa ttattcaata aaaaagttga attctttttt
    21361 acccaaccta ttcaacaatt ttattgaatt atatctttga aatacttctt atttagtatc
    21421 tcaaagaaac taagtgatac aaattggatt tttagaaggg ctaagttaac ctttttgaaa
    21481 ttcattcttt tattcttatg ctattcaatt atatgattga atagaagcga tttattttag
    21541 ataggagttt tttatgacga cacaactaac aaccgaaacg tttgcgaaag ctatccaaga
    21601 tggggtgagt cttatcgatt ttggggcgca atggtgccca ccttgtcgga tgatggaacc
    21661 ggtagtggaa gaactttcaa aggactttga cggaaaagca acgattgctc aggtggatgt
    21721 ggaccaatca caagatctgg ccaatctctt tggcattcgt tctatcccaa caatggtgat
    21781 ttttaaagat ggcaaacccg ttgatgctct tgttggtgtt catcctaaac aaacattgat
    21841 ggaaaaaatc caagcacagt tatcatgagg tgatttatgt atgatacaat tattgtaggt
    21901 tcaggacctg cagggtacac agctggcatt tatttaagtc gagctggttt gaaaaatcga
    21961 ttgatcacag gctattctga gggtggtcaa ttaaccacca caaccctcgt agaaaattat
    22021 ccaggttttg aaaacgggat tgaaggcaat aaattagtcc aaacaatgcg ccgccaagca
    22081 gaacagtttg gcaccgaaat gacttttgga tttgttcaaa aaattgaagg cgaatcgtct
    22141 cctttcaagg tacatctgga taatggtgaa atcattgata ccaaggccgt tattatcgca
    22201 acaggctcta gcgctaaata cctagggatt gaaggcgaag aagaggctgt cggaaaaggt
    22261 gtcagcgctt gtgcgacctg tgatgctttc ttctataaag agcgtgaagt ccttgtagtt
    22321 ggcgggggtg atgtcgctat ggaagaagcc ctctatttga cacgctttgc atcgaaagtg
    22381 accgttgtcc accgccgcaa tgagttacgc gcatctgata ttatggtcaa acgggctcag
    22441 gcaaatgata aaattcattg gatgttaaat tatacgcctg tcaaagttgc atctaatctg
    22501 atgggaatga ctggtttgga tgttcgtaat aatgaaacag gtgatattga gcacattcag
    22561 gctgacggtc tctttgtggc tattggtcat cagccaaaca ccgattttct tgatgggaaa
    22621 ttagcattgg atgataaagg ttatattcaa acacaggcag gaacagcaaa gacctctgtt
    22681 gcaggtattt ttgcagctgg tgatgtgcaa gatccaaaat atcaacaagc cattactgca
    22741 gcggggagcg gtgctattgc tgccctagat acattggcct atattgataa cctatgatgg
    22801 attcagtcac gtctagtatc gaattagaag aactgttaga cgaacatcaa aatctagctc
    22861 ttcttgtttc aggaaatcaa tgcagtctat cgtctcttgg acaaaaagaa ctcatagaca
    22921 cggctgaacg agagcatttg gtgctttacc aagcagatat ttttcaagtg ccccgtctca
    22981 tttctttatt tggcattcag cctaccctga cgagtttatt agtatttaaa aagggtcaat
    23041 tggttgatag gaaagaggtt taaatggcaa gaaaagcttt gatacaaagg aaaaagaagg
    23101 cctacccggt tcaagaatac tcacgctgtt tggcatgcgg ccgcccgcat tcggtctacc
    23161 gcaagtttaa actttgtcgg atttgtttac gccagcaagc ttaccaaggt gtcattcctg
    23221 ggttgaaaaa agcttcttgg tagtggaaag aaaggaagga aaaaatatgg aaattagtta
    23281 ctggtcagat attgcctgtc cattttgtta cattggtgct agtcggatga agcgtgctat
    23341 ggcagctgtt ggtttaaacc cggaagattt gacaatgaaa gcttaccagc taaatcccaa
    23401 tgcgccttta gaaacaagtg aaaccatgct cacagagttt gctaccagtc acggtatgac
    23461 cactgagcaa gttaaagctc agtttgcgca catggaaagc atgggaaatg aagaagggct
    23521 tcgtattgat atggcgggga ttatcccaac caacactttt tcagctcacc gtcttattaa
    23581 atggtcgcag aagtatttag ataaaaaaga tcatcaaaat ttcattacgg ccttgtacta
    23641 tctttacttt gaagaacatg ccaatattgc ggatcattct gtgttactag ctgttatcag
    23701 tgagttcgat ctaccacaag aagaggcagc gcaggttctt gctggagatg cgtttgctga
    23761 cgaggtcaaa cgcgatatct tagaagccca ccaatcaggc gttcaaggtg cacctttctt
    23821 tgttctgaac aataagtatg gcatttcagg tgcccagcct tatgaataca tgttagcgac
    23881 attaaaaaaa attcaagcag aggaaggagc acaataaaat gatagatacc ccttttcaac
    23941 tactagacag caattcagaa gagacaggtt tagtttgtgg gattgatggc tgtagcatag
    24001 atccctcaac acagccgtta gaaaatacct atcagccatt agaaaaaagt aaaaaagcag
    24061 tcattgggag gacagaatgg aaaaacaaag agtagaagcc ttgtcagatg ctatattggc
    24121 cattattgtt acaattatgg ctttggagtt acagttacct gaggaattga ctgtagcagg
    24181 acttagaagc atgctaccta tgctttttat ctacattact agttttttgc aaatcatggc
    24241 agtctggcta tattatcatg aactctacaa attagtagat catgtcagct ttcatttatt
    24301 tggagccaat agtttttggc ttttaacagc tagttttgtt cccttagcga ctcgagggat
    24361 tggacagaat tccgctaatt ttgcctttct cctgttttac ctcatcgttc ttgccctttg
    24421 ggatgtatct tggataatca tgacagcaat ggtgatcaag acgagtcaaa gacagttatc
    24481 agctgaagaa aaaaagatac cttatcggtg ggcactatta tatggattgc agctagtgat
    24541 catattatta gttggttatc tttttccaaa tttcattcct tttgctccgc tactgatgat
    24601 tattaatgtt atctatggtt ttttaagcaa caaatcttga aaaatactaa aaataatggc
    24661 taactagcat cggttataaa aactaggtct taagaaagct cgtaaagcat cacaatttag
    24721 taaacgttaa aacttattta tatttattga aagcatttcg tatcaaaaat acgggatgct
    24781 ttttctgttc accccaaata tttgaacctt gaacttccgt gaataggttc cattacgact
    24841 attaccagaa ttatagacta ctttatcgta aggttcatac tctaaaaggg ctgataattc
    24901 tgctttaagc aggtcgttca tagctgtttc aagagcagaa cgaaaaaatt cattgatatc
    24961 tcgttttttg actaggaagt taagaaattc tgtggtaaac tgtgtcatag aagtaaatct
    25021 ctttctagta atgtttcgca actctactat aacggattta ttcctttttg tgtttacaca
    25081 acttatttta cactacctgg tcgaataaca ttagaaacga atgtctttta tgttcgaggt
    25141 atagcacaat agtgggaata caggtagtat tgtactgaga ggtatcttat gtttagtaaa
    25201 ctaagtgacc atgactttaa aaaaggagtc tttagaacaa agttcagtca attagtaact
    25261 ccattaggaa aagaatctga ctgggctcat tcaaaaggtc cagaatatct ttggattgga
    25321 ttagctctgc aatatggaaa tcgaatagag caaatggaaa gagtgatgtt agctctgact
    25381 aatttatcaa aagcattaga tttagaaaaa atcttgcctt taccggcaat gagtttaata
    25441 cttaatttag atatcgatga gaagaaaatt tttgttgaat cactaaattc tgctttcgac
    25501 ttatcaatat tttctccgct ttcaataatt ttgcctgata gcgaagaggt tttgagtaaa
    25561 aatttttaca gcaagagtca ctcttttaat caaagactag atatacttgt taaagtacta
    25621 aatgaagtat ctgaccaata tagtcaatta tcgacggatg taagatattt tttactgtat
    25681 tacaagatgt tacagggaaa aattcaattt gtagaatcgc agttacacat ggtagacgga
    25741 ttaagtaagt acccttactt agatatatca gatccagaaa tgagaattat tcgtcctcag
    25801 attcgctcaa tggaggtagc tttatcaatg tccgaagata tgaattatcc ttatagtaaa
    25861 agattttgga ataatattag ccagctaact gattgtgagg tatattcaat tgttatggat
    25921 agaagtaata ctatagattt gaataagata aaagatacag tattttcgac attaaaatat
    25981 tacagagata tgcttcaaag tatagagcct tttaacgaga agctctatgt tttgactagt
    26041 atcctaacct attcttataa gcggttacta gaattaatga atcatggttt gcaatatacg
    26101 atttcaggtc gttccatagt aaggtcgtgc attgaaaact atgtgatgac aaaatattta
    26161 attgccgaag aagaaaaaca caaaaatatt tgggaagaat atcaatatta tggtattggt
    26221 ggatataaac tgatttcaga acgctatata gaaaatcaac ctgaattaac aaactctcat
    26281 attaattttg aatatctgaa tttactagta tctgaatttc aaaataaaga atttatagat
    26341 atggatacta gatatttcgg aaaagggaat ataagacaaa agtttgaaca agttgaggaa
    26401 gatgatttat ataaatatca ctatgattat gattctcaat ttgaacatgg actttgggga
    26461 gcgattagag aaagctcaat tttgaaatgc aactctgctg gacaccaatt ccacggtatt
    26521 cccgatatag acgatattca aaaattaccc gatgttagtc atgatctggt gatggtttta
    26581 acaaagcatc tatcagtgat taaagaagtg tttcctattc caagtgagca aatagaaggt
    26641 gatagtttat gctagataga ctaagacaat cacaaaatga atatttagag ttactgaaga
    26701 gagttagatg ggacttggac ttagagaatg tagcttatca tttagataaa attagaaatt
    26761 tttggtttag aaaacaaaaa ttattagaga tgtgtagcca atatctcttt aataattcga
    26821 acacatattt ttatacagca gtttctaaat ttaatgtaga taactcagat aagaacatca
    26881 tctttgcatt agggaattat caaatatttg acgatccaat actatcctat ttagaagtaa
    26941 tggaaaaagg aaatacagta catcaaatag aaagatactt caaaaaatta aaagaaaaaa
    27001 ttgtagagtc aatagatgat ttgatagttt tattagaaaa agagattcca aatttttacg
    27061 tattaccact aagattttct agttcaacta tcaacaaaga aaaagttgat atcagaccgt
    27121 ttattgaaaa cttctttata gaaggcattg attttaataa tttacacaag tacgagaata
    27181 tagatactgt ggtcgtacat gaatacttat cgcagatatt actctttgat tatgatgatc
    27241 ctacacaagc gataaaagac cgtttaaaac aatatcgaat tgagtactca gatatagtcc
    27301 cacaagatat gaatgataca gaacttttcc aatttattgt ctatggctat ttcagtcaag
    27361 ctatggatat ttttctgact tcctactctt tcaatatttc cccattcttt tctagcttaa
    27421 ctacatacat aaattataat gttttcttat taaatatcgt gcacaattcg aaaaaagaaa
    27481 aactagaaca tttcttaaaa atgtcaagat taaccttacc catttggttt gaatacgata
    27541 aaaaaggagt tgagctaagt atttctgaaa tacgtgaaag agcaaaaaat ataaactttt
    27601 cagatcgtat aagagagatt tataatgctc tcgatgattt caacaccaaa gagcagttga
    27661 ttactgaggt tgagaattgt gtacatttat tgataaatta tgaaggtaga ggttgctagt
    27721 aatgttgttt ctcaataaca taagctccga aaactaaaaa aatgataacc ctttgataac
    27781 ctctcgattt ttaaaagggt tatatatgta aagatcgagg atttatctct taaaattact
    27841 tgattttagt gataatttac cataaatatc ataatgtaga a
//
LOCUS       DAVKXA010000027        27346 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKXA010000027 DAVKXA010000000
VERSION     DAVKXA010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.027"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(728..820)
                     /locus_tag="VW883_001223"
     CDS             complement(728..820)
                     /locus_tag="VW883_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0274364.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            981..1952
                     /gene="ruvB"
                     /locus_tag="VW883_001224"
     CDS             981..1952
                     /gene="ruvB"
                     /locus_tag="VW883_001224"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0274365.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1933..2505
                     /locus_tag="VW883_001225"
     CDS             1933..2505
                     /locus_tag="VW883_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0274366.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDFETDVDVIFFDPDISYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTAFYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLFKKNWQEKWKNLIFKNT"
     gene            2736..3494
                     /locus_tag="VW883_001226"
     CDS             2736..3494
                     /locus_tag="VW883_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0274367.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALIKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3503..4306
                     /locus_tag="VW883_001227"
     CDS             3503..4306
                     /locus_tag="VW883_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0274368.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4328..5587
                     /gene="rseP"
                     /locus_tag="VW883_001228"
     CDS             4328..5587
                     /gene="rseP"
                     /locus_tag="VW883_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0274369.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5600..7453
                     /locus_tag="VW883_001229"
     CDS             5600..7453
                     /locus_tag="VW883_001229"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0274370.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7553..8932
                     /gene="bglA"
                     /locus_tag="VW883_001230"
     CDS             7553..8932
                     /gene="bglA"
                     /locus_tag="VW883_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0274371.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            9124..10932
                     /gene="glmS"
                     /locus_tag="VW883_001231"
     CDS             9124..10932
                     /gene="glmS"
                     /locus_tag="VW883_001231"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0274372.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLGGAENHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERTSYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(11070..11147)
                     /locus_tag="VW883_001232"
                     /pseudo
     CDS             complement(11070..11147)
                     /locus_tag="VW883_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            11204..12253
                     /locus_tag="VW883_001233"
     CDS             11204..12253
                     /locus_tag="VW883_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0274373.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(12353..16150)
                     /gene="spuA"
                     /locus_tag="VW883_001234"
     CDS             complement(12353..16150)
                     /gene="spuA"
                     /locus_tag="VW883_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0274374.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16567..16980
                     /gene="rpsL"
                     /locus_tag="VW883_001235"
     CDS             16567..16980
                     /gene="rpsL"
                     /locus_tag="VW883_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0274375.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            17000..17470
                     /gene="rpsG"
                     /locus_tag="VW883_001236"
     CDS             17000..17470
                     /gene="rpsG"
                     /locus_tag="VW883_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0274376.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17895..19976
                     /gene="fusA"
                     /locus_tag="VW883_001237"
     CDS             17895..19976
                     /gene="fusA"
                     /locus_tag="VW883_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0274377.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            20080..24471
                     /locus_tag="VW883_001238"
     CDS             20080..24471
                     /locus_tag="VW883_001238"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0274378.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24573..24836
                     /locus_tag="VW883_001239"
                     /pseudo
     CDS             24573..24836
                     /locus_tag="VW883_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            24829..25107
                     /locus_tag="VW883_001240"
     CDS             24829..25107
                     /locus_tag="VW883_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0274379.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPTRY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            25128..25280
                     /locus_tag="VW883_001241"
     CDS             25128..25280
                     /locus_tag="VW883_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274380.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGLF
                     SALKEK"
     gene            25302..26543
                     /locus_tag="VW883_001242"
     CDS             25302..26543
                     /locus_tag="VW883_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0274381.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(26597..>27346)
                     /locus_tag="VW883_001243"
     CDS             complement(26597..>27346)
                     /locus_tag="VW883_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0274382.1"
                     /translation="NQFIVKDITGKHAHLAHFENTSQHDYKRDKHKKTLNQSNVYSTS
                     LQVVRRASEEPIHYLCKYFGITATEESLKQLEEIGENISRMENTIDNLYQREKQIKTD
                     FNPPKFILKYFSKDLMKELDIHLPDIKVDYTSYIFEYVSAGGNSSQKTTILFNGETVE
                     ATAEYIAKKIKSKQTAQAQRSLMTNKLRTQIKERDHYTCQICAASTAEQSLLLLEIDH
                     IVPVSKGGLSTPDNLQTLCWKCNRSKSNKIL"
BASE COUNT         7685 a         5210 c         6372 g         8079 t
ORIGIN      
        1 aatcctaaac ttttttcatc acaatctcct aatgaagcca cccaatcagg tggctttttt
       61 gcgtggtgag gtgctggtga tagaaatttt ttgcaaaata gtaaaatttt agaaaagtta
      121 agctagtttt aagtttcgtc ttgtatcatg tagttattaa ataaagacct cctaacttta
      181 tttaataaaa tcctaaactt ttctttttca taataatctc ccttaactcc acccaatcag
      241 gtggagtttt ttagctctat ttcaggcttt tggggactat tctaaaaata atttttcgat
      301 atttttcggt atttttcgga ttttggtcgg ggaattggcg gggacttttt tagcgaatat
      361 aactaagaaa taggtctgtg gtcgcttcag ctagttcaaa ctcaatttga ttgtaagtga
      421 ctgttaattg aagaactgga actactgtaa taatgatttt gcttgtctag tagtggcgta
      481 ttaaatgaga agtgacatgt aagattgtct cttcgtttac gaaatcaaaa tttctatgaa
      541 attgatagaa tccctaacgt tctcttaatc ttaaccgtct tgtcgtacag cggttgaaga
      601 aaatgtaaac ctttgacaaa attcgtgaac tatgggataa taaaaaggaa ttgagtacta
      661 gttctatatc ataggctaga aaagacccca agctcacgac caaataagct tgaggtcttt
      721 tttgacacta tttgtccttg tttagccatt tatcgactat acgaagaacg acaccgacca
      781 caattggtcc gatgatagtt ttgagtacta attccatcat gggctatctc acctcctttc
      841 gtaggcggtg tagcagtgtt gtataatatt ataccacata agtgctaaac ttaggagtca
      901 cccaatcagg tggctttttt gtttgtggct tggttttttg atataataga gccatgagta
      961 gaattttaga taatgagata atgggggatg aggagttagt agaacgcacg ctccgtcctc
     1021 agtatttacg tgaatatatc ggacaggata aggtcaagga ccagctacaa atctttattg
     1081 aagctgccaa aatgcgggat gaagcgctgg atcatgtgct cttatttggg cctccaggtc
     1141 tcgggaaaac gaccatggcc tttgttattg ccaacgaact gggagtcaat cttaagcaga
     1201 cgtcgggtcc agtcattgaa aaagccggag atctggtagc tattttgaat gagttagagc
     1261 ctggggatgt actttttatt gatgagatcc atcgtttgcc aatgtcagtg gaagaggtgc
     1321 tttatagtgc tatggaggac ttctacatag atattatgat tggggctggt gagggtagtc
     1381 gtagtgttca tttggagtta ccacctttta ccttgattgg tgcgacgact cgggctggta
     1441 tgctctccaa tccgctacgg gcacgttttg ggattacagg ccatatggag tattatgccc
     1501 atgctgactt gacagaaatt gtcgagcgga cggcagatat ttttgagatg gaaatcactc
     1561 atgaggcagc atctgagttg gccctacgta gtcgtgggac ccctcgtatt gccaatcgtc
     1621 tcctcaagcg cgtgcgcgat tttgcccaga taatggggaa tggggtaatt gatgatatta
     1681 ttaccgataa ggctttgact atgctggatg ttgaccatga aggtttggac tatgtggatc
     1741 aaaaaatcct tcgtaccatg attgagatgt acagtggagg acctgttggt ctaggaactc
     1801 tttctgtgaa tatcgccgaa gagcgtgaga cagttgaaga tatgtatgag ccttacttga
     1861 ttcaaaaagg ttttatcatg cggacacggt ctggacgggt ggcgactgct aaggcatatg
     1921 agcacttagg ttatgaatac agtgaaaaat aagcaagaaa tcttagaggc ttttagagaa
     1981 aatccagata tgatggccat tctgacgatc atccgagacc ttggtctgaa agactcgtgg
     2041 ttggcagcag gttctgtcag aaatttcatc tggaatctct tgtcagacaa atcacctttt
     2101 gactttgaaa cagatgtaga tgtgattttc tttgatccgg atatttctta tgaggaaacc
     2161 ttattactgg agaaaaagct gagagaggat tttcctcagt accagtggga attgaaaaat
     2221 caggtctata tgcatcagca cagtcctcac actgctttct ataccagttc tcgtgatgct
     2281 atgagtaagt atccagaacg gtgtacggca gttggactgc gcttgaatga agaatcagat
     2341 tttgaactct atgtacctta tggtttggag gatattttga attttcaagt tcgtccaact
     2401 cctcatttct tagaaaatga agaccgaatg gaactctatc aaacacgttt attcaagaaa
     2461 aattggcagg agaaatggaa aaatttgatt tttaaaaata cttaaggaaa ctttaagcta
     2521 gggagtgtac actaagttca taagttaaga aaaccttaac ttaaactcct aaaacttttt
     2581 cataataatc tccctataaa aataaagtcg cccaatcagg cggcttattt ttttgaaaaa
     2641 tgggcttggt gcctgagaat aaatagctta gtgatagaag aaaatgggga aatatggtat
     2701 aatgaaacga tagatttttg aataggaata agatcatgtt tggatttttt aagaaagata
     2761 aggctgtgga agtagaggtt ccgacacagg ttcctgctca tatcggcatc atcatggatg
     2821 gcaatggccg ttgggctaaa aaacgtatgc aaccgcgagt ttttggacat aaggcgggca
     2881 tggaagcatt gcaaaccgtg accaaggcag ccaacaaact gggcgtcaag gttattacgg
     2941 tctatgcttt ttctacggaa aactggaccc gtccagatca ggaagtcaag tttatcatga
     3001 acttgccagt agagttttat gataattatg tcccggaact acatgcgaat aatgttaaga
     3061 ttcaaatgat tggggagaca gaccgcctgc ctaagcaaac ctttgaagct ttaatcaagg
     3121 ctgaggaatt gactaagaac aacacaggat tgattcttaa ttttgctctt aactatggtg
     3181 gacgtgctga gattacacag gcgcttaagt tgatttccca ggatgtttta gatgccaaaa
     3241 tcaacccagg tgacatcaca gaggaattga ttggcaacta tctctttacc cagcatttgc
     3301 ctaaggactt acgagaccca gacttgatta tccgtactag tggagaattg cgtttgagca
     3361 atttccttcc atggcaggga gcctatagtg agctttattt tacggacacc ttatggcctg
     3421 attttgacga agcagccttg caggaagcta ttcttgccta taatcgtcgc catcgccgat
     3481 ttggaggagt ttaggaggaa atatgaccca ggatttacag aaaagaacct tgtttgcagg
     3541 gattgccctg gctattttcc taccaatttt aatgattggg ggcctcttgc ttcagatagc
     3601 aatcggaatc atagccatgc tagccatgca tgaacttttg aagataagag gtctagcgac
     3661 catgacgatg gagggcctct tgactctctt tgcaaccttt gcattaacca ttcccttgga
     3721 gaattacctg acttttttgc cagttgatgg gaatgtggtt gcctatagtg ttttgatttc
     3781 aatcatgtta ggaacgaccg tttttagcaa gtcttatacg attgaggatg cggttttccc
     3841 tcttgctatg agcttctacg tgggctttgg atttaatgct ttactagatg ctcgtgttgc
     3901 aggtttggac aaggctctct tagccttgtg tatcgtctgg gcgacagaca gtggtgccta
     3961 tcttgttggg atgaactatg ggaaacgaaa gttagcacca agggtatcgc ctaataaaac
     4021 ccttgagggt gccttgggtg gtattttagg agcaatttta gtaaccatta tctttatgat
     4081 agttgacagt acagttgctc ttccatatgg aatttacaag atgtcagtct ttgctatttt
     4141 ctttagcatt gctggacaat ttggtgattt actagaaagt tcgatcaaac gtcattttgg
     4201 tgttaaggat tctgggaaat ttatccctgg acatggtggt gttttggatc gtttcgatag
     4261 tatgttgctt gtatttccaa tcatgcactt atttggactc ttttaatcaa aagacggagg
     4321 aaacgctatg ctcggaattt taacctttat tctggttttc gggattattg tagtggtgca
     4381 cgagttcggg cacttctact ttgccaagaa atcagggatt ttagtacgtg aatttgccat
     4441 cggtatggga cctaaaattt ttgctcacat tggcaaggat ggaacggcct ataccattcg
     4501 aatcttgcct ctgggtggct atgtccgcat ggccggttgg ggtgatgata caactgaaat
     4561 caagacagga acgcctgtta gtttgacact tgctgatgat ggtaaggtta aacgcatcaa
     4621 tctctcaggt aaaaaattgg atcaaacagc cctccctatg caggtgaccc agtttgattt
     4681 tgaagacaag ctctttatca aaggattggt tctggaagaa gaaaaaacat ttgcagtgga
     4741 tcacgatgca acggttgtgg aagcagatgg tactgaggtt cggattgcac ctttagatgt
     4801 tcaatatcaa aatgcgacta tctggggcaa actgattacc aattttgcag gtcctatgaa
     4861 caattttatc ttaggtgtcg ttgttttttg ggttttaatc tttatgcagg gtggtgtcag
     4921 agatgttgat accaatcagt tccatatcat gccccaaggt gccttggcca aggtaggagt
     4981 accagaaacg gcacaaatta ccaagattgg ctcacatgag gttagcaact gggaaagctt
     5041 gatccaagct gtggaaacag aaaccaaaga taagacggca ccgactttgg atgtgactat
     5101 ttctgaaaag gggagtgaca aacaagtcac tgttacaccc aaagatagtc aaggtcgtta
     5161 ccttctaggt gttcaaccgg gggttaagtc agattttcta tccatgtttg taggtggttt
     5221 tacaactgct gctgactcag ctctccgaat tctctcagct ctgaaaaatc tgattttcca
     5281 accagatttg aacaagttgg gtggacctgt tgctatcttt aaggcaagta gtgatgctgc
     5341 taaaaatgga attgaaaata tcttgtactt cttggcaatg atttccatca atattgggat
     5401 ttttaatctt attccgattc cagccttgga tggtggtaag attgtgctca atatcctaga
     5461 agccatccgc cgcaaaccat tgaaacaaga aattgaaacc tatgtcacct tggccggagt
     5521 ggtcatcatg gttgtcttga tgattgctgt gacttggaat gacattatgc gactcttttt
     5581 tagataatcg aggaatatta tgaaacaaag taaaatgcct atcccaacgc ttcgcgaaat
     5641 gccaagcgat gctcaagtta tcagccatgc tcttatgttg cgtgctggtt atgttcgcca
     5701 agtttcagca ggtgtttatt cttatctacc acttgccaac cgtgtgattg aaaaagctaa
     5761 aaacatcatg cgccaagaat tcgaaaagat tggtgctgtt gagatgttgg ctccaaccct
     5821 tcttagtgca gaattgtggc gtgaatcagg tcgttacgaa acctatggtg aagaccttta
     5881 caaactaaaa aaccgtgaaa aatcagactt tatcttaggt ccaactcacg aagaaacctt
     5941 tacagctatt gtccgtgatt ctgttaaatc ttacaagcaa ttgccactca acctttatca
     6001 aattcagccc aagtatcgtg atgaaaaacg cccacgtaat ggacttcttc gtacacgtga
     6061 gtttatcatg aaggatgctt atagtttcca cgctaactat gatagtttgg atagtgttta
     6121 tgatgagtac aaagcagcct atgagcgtat tttcactcgt agtggtttag acttcaaggc
     6181 tattattggt gacggtggag ccatgggtgg taaggatagc caagaattta tggccattac
     6241 atctgctcgt acagaccttg accgctgggt tgtcttggac aagtcagttg cctcatttga
     6301 cgaaattcct gcagaagtgc aagaagaaat caaggcagaa ttgctcaaat ggatagtctc
     6361 tggtgaagat accattgctt actcaagtga gtctagctat gcagctaact tagaaatggc
     6421 aacaaacgag tacaaaccaa gcaaccgtgt tgtcgctgaa gaagaagtta ctcgtgttgc
     6481 aacgccagat gttaaatcaa ttgatgaagt tgcagccttc ctcaatgttc cagaagaaca
     6541 aacgattaaa accctcttct acattgcaga tggtgagctt gttgcagccc ttctagttgg
     6601 aaatgaccaa ctcaacgaag tcaagttgaa aaatcacttg ggagcagatt tctttgacgt
     6661 tgctagcgaa gaagaagtgg cgaatgttgt tcaagcagga tttggttcac ttggaccagt
     6721 tggtttgcca gagaatatta aaattattgc agatcgtaag gtgcaagatg ttcgcaatgc
     6781 agttgtcggt gctaacgaag atggctacca cttgactggt gtgaacccag gccgtgattt
     6841 tactgcagaa tatgtggata tccgtgaagt tcgtgagggt gaaatttccc cagatggaca
     6901 aggtgtcctt aactttgcgc gtggtattga gatcggtcat attttcaaac tcggaactcg
     6961 ctactcagca agcatgggag cagatgtctt ggatgaaaat ggtcgtgctg tgccaatcat
     7021 catgggatgt tacggtatcg gtgtcagccg tcttctttca gcagtgatgg agcaacacgc
     7081 tcgcctcttt gttaacaaaa cgccaaaagg tgaataccgt tacgcttggg gaatcaattt
     7141 ccctaaagaa ttggcaccat ttgatgtgca tttgattact gtcaatgtca aggatgaaga
     7201 agcgcaagcc ttgacagaaa aacttgaagc aagcttgatg ggagctggtt atgaagtctt
     7261 gacagatgac cgtaacgaac gtgtcggtgt taaatttagc gatagtgact tgattggtct
     7321 tccaatccgt atcactgttg gtaaaaaagc ggccgatggc attgtagaag ttaagatcaa
     7381 ggcaactggt gacaccattg aggttcatgc agataacgtg cttgaaacgc ttgaaatcct
     7441 aagcaagaaa taaaaactat aatcagaaga aaaacaagga aaaaatgtaa ctagttttta
     7501 ccttgttttt tctgtataat gggagaaatg agtagataaa gaggtaaatg ttatgctaag
     7561 atttccaaag gattttgtct ggggatcctc tacttctgga ccgcagacag aaggacgtgt
     7621 agctggtgac ggtaagggag acaatctctg ggattactgg ttccaagtgg agccaaatcg
     7681 ttactataat gggattggtt cagataagac atcgactttt tatgaaaatt gggagcggga
     7741 tattgagctt ttgttagaga ctggtcacac agtctttcgg acttctattc agtggtcacg
     7801 gatttttcca caaggctgtg gaaaagtcaa ccctcaaggt gtggattttt atcgtaaggt
     7861 ctttgaggct attaaggcta aaggaattcg tctgttagtc aatctctatc attttgattt
     7921 accttttgcc cttcaagagg atggtgatgg ttgggaaaat aaggcgacag tctcagccta
     7981 tgaagactat gctcgttttt gttttgagac ttatggagat ttagtggatc aatggattac
     8041 ctttaacgag cccatcgttc ctgtagaatt tggttatttt tatgatgccc attatccaca
     8101 taaggtggat gcagaggcag ctgttaaggt agcctatcat acacaattgg ccagcagccg
     8161 ggctgttaag gcttgccatg aacttttgcc tgattccaag attgggattg tcctcaactt
     8221 gacaccggct tatccacgta gccagcatcc tgctgatgtc aaggcagctc gtattgcggc
     8281 cctttttcag gcccaatctt tcttagatcc atctgtcttg gggacttatc cacaggagtt
     8341 ggtagaaatc ttgcatgaac acggtctttt acctgatgct acagaggaag agttggaact
     8401 cattcgtgat aatacggtgg acttccttgg tgtgaactac tatcaacctt tgcgtgttat
     8461 ggctcctcga tttgctaagc atccagagag tccactctta ccagaacatt tttacgagcc
     8521 ttatgtgatg cctggacgta aaatcaattc tcatcgtggt tgggagattt atgagcaagg
     8581 gatttatgac atcgcccaaa atatcaagga aaattatggc aatattgagt ggatgttgac
     8641 tgagaatggt atgggtgttg aaggggaaga aaaattccgt caagatggaa tgattcaaga
     8701 tgattaccgt attgactttg taaaaggtca tcttcgtgaa cttcaccgtg ccattgaaga
     8761 tggtgccaac tgtaagggct acttgatttg gacctttatt gactgctggt catggctcaa
     8821 cagctataaa aatcgctatg gtttggtcga attagacttg gaaacgcaag aacgtcgtct
     8881 gaagaaatca ggccactggt tcaaaaaatt aagcgataat aatggatttt aaaaaggact
     8941 ctgactgatt atcccaatcg gtcagagttt tttgcttaca ggagcttaat ttgaactata
     9001 ccaattttta ctcttgacaa gtgaaagaaa caagtatata ctgtttttgc tgattctata
     9061 aaagatgaat tagactatac caattttaag gagaaagcac agcttgcctg tgtcgtatat
     9121 actatgtgtg gaattgttgg tgttgttgga aacacaaatg caactgatat tttgattcaa
     9181 gggcttgaaa agcttgaata ccgtggctat gattctgcgg gaatttttgt cctaggtggt
     9241 gctgaaaatc acctagtcaa ggcggttggt cgtattgcag aattgtctgc caagacagct
     9301 ggtgttgagg gaacaactgg tatcggacat actcgttggg ctactcacgg aaaaccaact
     9361 gaggacaatg ctcacccaca ccgctctgag acagaacgtt ttgtcttggt tcacaatggg
     9421 gtgattgaaa actaccttga aatcaaggaa gaataccttg caggtcacca cttcaagggg
     9481 cagacagata ctgaaatagc cgttcatttg attggaaaat ttgcggaaga agaagggctc
     9541 tcagttcttg aagccttcaa aaaagccctt cacatcatcc gtggttctta tgcctttgcc
     9601 ttggttgact cacaagatcc tgaagtcatc tacgtagcta aaaataaatc accacttttg
     9661 attggtcttg gagaaggcta taacatggtc tgctcagacg ccatggctat gattcgtgaa
     9721 actaaccaat acatggaaat ccatgaccaa gagttggtaa tcgtcaaggc tgatagtgtg
     9781 gaagttcaag actatgatgg aaatcgtcgt gagcgtacta gctacactgc tgaacttgac
     9841 ttgtcagata tcggtaaggg aacttaccct tactacatgc tcaaggaaat tgacgagcaa
     9901 ccaactgtta tgcggaaact catccaagcc tacacagatg aggctggtca agttgtcgta
     9961 gacccagata tcattaaggc tgttcaagac gcagaccgca tctacatcct tgcagctgga
    10021 acatcttacc atgcaggatt tgcttctaag aaaatgttgg aagaattgac agatacacca
    10081 gttgaacttg gaatctcatc tgagtggggc tacggtatgc cacttctcag caagaaacca
    10141 ctcttcatct ttatcagcca atctggtgaa acagcggata gtcgtcaagt tttggtcaag
    10201 gctaatgaaa tgggaattcc aagcttaaca gtgacaaacg ttccaggttc aaccctctca
    10261 cgtgaagcca actataccat gctccttcac gcaggtcctg aaattgccgt ggcatcaact
    10321 aaagcctata cagcgcaaat cgcagccctt gccttccttg caaaagcagt cggagaagca
    10381 aatggtaatg ctaaagcgca agcctttgac ctggttcatg aattgtcaat cgtagctcag
    10441 tctatcgaat caactctttc agagaaagaa accattgaag ccaaggttcg tgaacttctt
    10501 gaaacaactc gtaacgcctt ttacatcgga cgtggtcaag attactacgt agccatggaa
    10561 gcaagtctca aactcaaaga gatttcttat atccagtgtg aaggttttgc ggcaggagaa
    10621 ctcaagcacg gaaccattgc cttgattgaa gaaggaacgc ctgtcttgtc tctcttgtca
    10681 gatccagttc ttgccaacca tactcgtgga aatatccaag aggtcgcagc ccgtggtgcc
    10741 aaagtcctca ctatcgcaga agagaatgta gccaaagata ccgacgatat cgtccttacg
    10801 accgtacatc catacctctc accaatttca atggtcgtac caacgcaatt agtcgcttac
    10861 tttgcaaccc tccaccgtgg cctcgatgtg gacaaaccac gtaaccttgc caagtcagta
    10921 acggtagaat aagctaaaaa agtctagtta tctaggcctt tttcttgtga gcaaattggt
    10981 tgcttgtact caagattcgt gttatactct tcgaaaatct cttcaaacca cgtcaacgtc
    11041 gccttgccgt aggtatggtt actgacttcg tcagttctat ccacaacctc aaaacactgt
    11101 tttgagcagc ctgcagctag cttcctagtt tgctctttga ttttcattga gtattagaat
    11161 aatttttcaa attgaagtac agagatagat aaggagaatc acaatggtag aattgggaat
    11221 ttcaacattt ggggaaataa cggagcttga agggactgga caaacttaca gtcatgctga
    11281 acgcattcgc cagttggtgg cagagattga gctggctgac aaggttggtt tggacgtata
    11341 tgggattggc gagcaccatc gggcggattt tgcagtatca gccccagaga ttgtcctggc
    11401 cgctggggca gtcaatacca agaaaatccg tttgaccagt gcagtcagca ttctgtcaag
    11461 catggatccg attcgtttgt tccaacagta tgccactatc gatgctttgt caaatggacg
    11521 atcggagatt atggctggaa ggggctcttt cacggaatct ttccctctgt ttggttatga
    11581 cttgaaagac tacgactctc tttttgatga gaaattagac ttgcttcagt tagtcaatga
    11641 aaagaccaag ttagactggc aaggtcgatt gactcaaacg attgctggta aagaagttta
    11701 tcctcgtcca gttcaggaca aattgccctt gtggatagct acaggtggtc atgtcgaatc
    11761 aacagtgaag attgctcagg ctggtctacc gattgtatat gctattattg gtggtaatcc
    11821 acgttatttt aaaaagttga ttcaggctta tcgtgagatt ggaagcgaag cgggccatgc
    11881 tgacaaagac ttgaaagtgg gagcccattc ttgggggtgg attgcggaag atggtgagca
    11941 ggcggtgaaa gattatttcc atccgactaa gcaagtggtg gatgctattt ccaaagaccg
    12001 tccgcactgg caggaattgc gttatgagca atatttggag caggtagggc caaatggcgc
    12061 catgtttgtt ggcaatccag atcaggtggc cgaaaaattg attcgcatga tagaggattt
    12121 aggattggac cgcttcatgc ttcatctacc gcttggttct atgcctcatg accaggttct
    12181 gagagctatt gaactcttcg gaacacaagt tgcacccaaa gtacgagctt attttgctat
    12241 gaaagaggct taataaaaaa tcctaatcaa gtttattagg acaacaaata ttgtacaaaa
    12301 attaatcccc cgagctataa tgcttggggg atttttctat aggagggcta gtttagttct
    12361 cttttttatt ttttagtaag aaaccgagac caaggagcgc aaggaggctg attcctgcaa
    12421 ataggagttt gttttcgttt ttgattcctg tatttggaag ttcagcttgt ttatctgggg
    12481 ttgcaggtat attttccttg ctagagtttt ctaccgattc gtttcgaacc gcttctttta
    12541 cagatgatgc ttgtgcttct tgtgctggtt gttcagcttg tgaatcagct gtagcttggc
    12601 taggtttatt ttccgcatca gctactttgg catctggttt agtagaatca ggtctagctt
    12661 ctggagctgg gtcttgatgt gcagggtgag aagcttcatt ttgatgttca ggcttggaag
    12721 gggttgagtc tggtttctct tctgcagttg actcatggct agttccattt tgagagactc
    12781 gaagaacagt agctgtaagg gcattcaatt tcaagccttt ttcagtccat tcaagtcctt
    12841 tcgggttggc aattccgact gatcctgctt ggttttcatc tgccaaaact tccgcatttc
    12901 ttagatgtgc aaaggcagtt cccaaattaa attcgcgagc tttttcatcc gcattgacaa
    12961 agactgcgta gatatcgccg tttggagcag tgatttggta gccaatcact acatcctctt
    13021 tttccacacc attttggcct gggacagtga tgaggtggac acggtctttg atatcttgga
    13081 gactcttaag tcggaaggca tctgtagatt gacgaagggc aatcaaacct ttcatatagt
    13141 cacggctctt gacattttca ggataagctt taccatctgt agccttagtc cagtcaaact
    13201 tgttgactgc gtcgctagaa tcgtaagaat catggatgaa gtaaggatag tcaaatgggt
    13261 tgccgtcctt atcacgcaac aagtgagatt tgtttggaac cttatcctct gctactggag
    13321 tcttgtaggc tgggtcacgg aattgtttag tacgtccata ttcctgaccg gagtggataa
    13381 atggagttcc ttgagctgtc aagaccatga gatttccaag tcgtaaacga cggtggattt
    13441 cagcatagtt ctcagccttg cttgggtctt ttttgataga ctgggcaatg atgtcaaaga
    13501 gggtcaagtt atcatgggct gcgatgtatt ggatgacatc tccagggctg tcagcttcaa
    13561 agttagttgg ttgagcaatg agatttttaa agatggtgtt gacatcacgc ttgccacctg
    13621 tgataaaggc aggttgacct tcgtttggat aaccagattt gaggttgtta cggatgtcat
    13681 ctgaaaagac agcgacagta tcggtatgtt tcatccaatc ttggtcagca gctttagtag
    13741 gcatgttttc atcaccggca taggttctcc aaccttcacc aagcatgatg aggtttggat
    13801 tgagggcgcg tgcagccttg taagcttctt cgatagaagc ggcgtcatgg tctcccatca
    13861 tatcgaagcg gaagccatcc actttgtagg tatcaactag gtatttgata gagtcaacta
    13921 ggagccgttt ggtcatatgg tgggttgtcc ccaagcgtcc accaccaaag ctagttcgag
    13981 gtgtgccatc ggcatccata aagtggtagt agtttggctc taggtcttca aagatatcga
    14041 ctttggctgt gtggttataa acgacatcta ggatagctcc cataccacgt ttgtggattt
    14101 cgttgatgag gtttttaaat tctgcgattc gtttttctgg attcttagga tcgcttgagt
    14161 acataccagt caaggagaag tagttttgag ggtcatatcc ccagttgtag ttgctgttgc
    14221 ttgaagcgta gtcagacaag cgttcatggt ttttcaattc attgacaaag tagtaagaca
    14281 agactggaag gagctggata tgggttacac ccaagtcttt gagatagtct agtttttcaa
    14341 tgaaggcttc aaaagtccca aatggtttgg tcaagtcttt tgcaatggca ggatctgaag
    14401 tgaagtcacg cacatgagct tcgtagataa cggcgtcttc acgagtcttg aaattgtgaa
    14461 tcttaccata agtcaagtct tgaggtccga gtttagctgg atctacaaag gcggctttag
    14521 ccactttatg ggcatcgtca attttggcat cgtcgctatt ccaagcagca agagatttag
    14581 cgtaaggatc gagtgcaaga acagttttac cttgacgctc gatttggtat tgataatagt
    14641 agccagtgaa atctgtgatt ccgagtttgt ttgtgctgtc tagagtttgt ttccaagttc
    14701 ctctttcccc tttttcgaga gcgacagttc caactacttt gtcagggtca ttcttgtcgt
    14761 agacaacaac agaaacctta tcagcacttg gtgaccaaag ggtcaaatca acttgttttc
    14821 cttcttcttt taggtcagct cccagtttgc catcatagct gtatgtctca tctttcaggc
    14881 gccagcttgt tttggtagtg aattggtcgg aattgtagct aacagtataa ggatgttttg
    14941 tgtcagagaa atctccgctg taggtcactt tcttaccagc ttcatcgatt gcaacatcgg
    15001 taatagttac cttgtttcct aggtgattag tgatgttgga gtgtttgagg atatcttctt
    15061 ttttagcacc gacaagtgtt gaaaagctac tttcaatgct agaagtgcct acgtgttggg
    15121 ctcctgtcat acggatatca tggacatagt atggatttgt gtaaatcgat tcatcatcgt
    15181 cttttaggaa aatttggcta tgatttttca aatctgtgaa cttataattt tctttacgga
    15241 ttttcacgtc gtctccttgt ttgctctcat ctagtaataa aaatccaaat tctcttgcgg
    15301 cttcattaag aggaatgtcg atatagcggc catatttgcc tgtagccgta aagtctgttc
    15361 cgtcaggcca ttgagcgcta cttggatttt ttacatctcc ccagtaccag agagatttct
    15421 tgtcatagtt gccatctgtg cggtagtagt tgacgcgaac agttcctgca ggctgtggct
    15481 cgtaagagaa aaccttgtaa tcttggtcta accaagcctc gttcattttt ggaactagtt
    15541 tttctacaga tttatcgccg gttagatttt ttccagctgt attgttgatg aggaagctaa
    15601 ttttcttggc ttgttctccc tttaatttga catctaggta atagccgtag tcatctttct
    15661 tggcatcctt gaaggacaaa gctccgtttg gccagttttc agatggtttt tcaacatcgt
    15721 cccaagtcca tagtccttga gcatccttgt tttcttcagg aagttttttg acatggatac
    15781 ggaagtagtt atcttcgatg ggctcttctg ccttagtttc agttgttact ggactagtag
    15841 aagtagttgg ctctgttgca ggtttttctt ctgttttctc tagggaagcg tttgcatttc
    15901 taggtgaaga aatatcactt tcgttcttac cagagccagc tgctgtatca gtaagaggtt
    15961 gggcaagggt ggttgtattt ctgttgttgg gttcgttagt ggttggtgta ctttcgtcgg
    16021 atgagatagt tggtgtagcc atggcaagca agacaaggct tgcgccgata aggacagaac
    16081 cagttccatt tttgagggaa cggatgctgt agaccatttt tttctcagtg tgagatggtg
    16141 tttttctcat aatgattctc caatcaataa atttctatat cagtatagca tgtagtaaaa
    16201 caatatgcaa gcgttttctt tgatttgtga aaaaaattct tacttttgag aagttttctg
    16261 tactatttta tatatcagta taaatgacgg agataaaaat gtcacataag ccaagccgta
    16321 ttattaggaa gatgatgtgt tcccagctat ttttattcag aaattgatct ctaacattac
    16381 caataaaaaa gaaaaatatc ttgacaagca agggaaaatt ttgttacaat aatagacggt
    16441 actttttact tttggtctct caagagtgta cagggacgtg ctgacaaatg ttgcaaaagt
    16501 acacacagat gatatctgtc accaagtgta tcatcaccaa aaataaaaaa acacaggaga
    16561 atgtagatgc ctacaattaa ccaattggtt cgcaaaccgc gtaaatcaaa agtagaaaaa
    16621 tctaaatcac cagctttgaa cgttggttac aatagtcata aaaaagttca aacaaacgtt
    16681 tcttcaccgc aaaaacgtgg tgttgcaact cgtgttggaa caatgacacc taaaaaacct
    16741 aactcagccc ttcgtaaatt cgctcgtgta cgtttgagca accttatcga agttactgcc
    16801 tacatcccag gtatcggaca caacttgcaa gagcacagcg tggtgcttct tcgcggtgga
    16861 cgtgtaaaag accttccagg ggtacgttac catatcgtcc gtggtgcact tgatactgca
    16921 ggtgttaacg atcgtaaaca aggccgttct aaatacggta ctaaacgtcc aaaagcataa
    16981 ggaaagggga taaagagaaa tgagtcgtaa aaatagagct ccaaaacgtg acgtattgcc
    17041 agatccgcta tacaattcac aactagttac tcgtcttatc aaccgcgtta tgcttgatgg
    17101 taaacgtggt actgctgctt caatcgttta cggtgctttt gagcaaatca aagaagctac
    17161 tggcaacgat gcacttgaag tatttgaaac agctatggaa aacatcatgc ctgtacttga
    17221 agtacgtgca cgtcgtgttg gtggttctaa ctaccaagtc ccagttgaag ttcgtccaga
    17281 acgtcgtaca acacttggac ttcgttggtt ggtaacaatc gctcgtcttc gtggtgaaca
    17341 cacaatgcaa gaccgtcttg caaaagaaat cttggatgct gctaacaaca ctggtgcagc
    17401 tgttaagaaa cgtgaagata ctcaccgtat ggctgaagct aaccgtgcat tcgcacactt
    17461 ccgttggtaa gataggatgc gaaagcgtta agaaagtccc agagaaaata gggaatcgaa
    17521 gcaggttgcg gttgcaacca atgagattca tctttttctc cagactttta gcttgagctc
    17581 aactaaatca tgatgctagg cacggtaagg atgcaaggtg aaaataggaa actgacgcag
    17641 tattcaacga atacaaggag ttttatcttt ttcacgcagc atcccgttcc agctcacatc
    17701 ggctaactaa ctttagcccg ggttcaaatt agctaaatcg attagtatta gctataactc
    17761 agcttaccat ctcgtaagtt gaaaccaaca atagcatgaa aacattgaga acgggtaggt
    17821 cctgcctatc cgtttttatt aaaatcgtgt tataatagaa tagaaatcaa aaataaatag
    17881 gagaaacaaa cctcatggca cgcgaatttt cacttgaaaa aactcgtaat atcggtatca
    17941 tggctcacgt cgatgccggt aaaacaacaa ctactgagcg tattctttac tacactggta
    18001 aaatccacaa aatcggtgaa actcacgaag gtgcgtcaca aatggactgg atggagcaag
    18061 agcaagaacg tggtatcacg atcacatctg ctgcgacaac agctcaatgg aacaaccacc
    18121 gcgtaaacat catcgacaca ccaggacacg tggacttcac aatcgaagta caacgttctc
    18181 ttcgtgtatt ggatggtgcg gttaccgttc ttgactcaca atcaggtgtt gaacctcaaa
    18241 ctgaaacagt ttggcgtcaa gcaactgagt acggagttcc acgtatcgta tttgccaaca
    18301 aaatggacaa aatcggtgct gacttccttt actctgtaag cacacttcac gatcgtcttc
    18361 aagcaaatgc acacccaatc caattgccaa tcggttctga agatgacttc cgtggtatca
    18421 ttgacttgat caagatgaaa gctgaaatct atactaacga ccttggtacg gatatccttg
    18481 aagaagacat cccagctgaa taccttgacc aagctcaaga ataccgtgaa aaattgattg
    18541 aagcagttgc tgaaactgac gaagaattga tgatgaaata cctcgaaggt gaagaaatca
    18601 ctaacgaaga attgaaagct ggtatccgta aagcgactat caacgttgaa ttcttcccag
    18661 tattgtgtgg ttcagccttc aaaaacaaag gtgttcaatt gatgcttgat gcggttatcg
    18721 actaccttcc aagtccactt gacatcccag caatcaaagg tattaaccca gatacagacg
    18781 ctgaagaaac tcgtccagca tctgacgaag agccatttgc agctcttgcc ttcaagatca
    18841 tgactgaccc attcgtaggt cgtttgacat tcttccgtgt ttactcaggt gttcttcaat
    18901 caggttcata cgtattgaat acttctaaag gtaaacgtga acgtatcgga cgtatccttc
    18961 aaatgcacgc taacagccgt caagaaatcg acactgttta ctcaggtgat atcgctgctg
    19021 ccgttggttt gaaagatact acaactggtg actcattgac agatgaaaaa tctaaaatca
    19081 tccttgagtc aatcaacgtt ccagaaccag ttatccaatt gatggttgag ccaaaatcta
    19141 aagctgacca agacaagatg ggtatcgccc ttcaaaaatt ggctgaagaa gatccaacat
    19201 tccgcgttga aacaaacgtt gaaactggtg aaacagttat ctcaggtatg ggtgaacttc
    19261 accttgacgt ccttgttgat cgtatgcgtc gtgagttcaa agttgaagcg aacgtaggtg
    19321 ctcctcaagt atcttaccgt gaaacattcc gcgcttctac ccaagcccgt ggattcttca
    19381 aacgtcagtc tggtggtaaa ggtcaattcg gtgatgtgtg gattgaattt actccaaacg
    19441 aagaaggtaa aggattcgaa ttcgaaaacg caatcgtcgg tggtgtggtt cctcgtgaat
    19501 ttatcccagc ggttgaaaaa ggtttggtag aatctatggc taacggtgtt cttgcaggtt
    19561 acccaatggt tgacgttaaa gctaagcttt atgatggttc atatcacgat gtcgactcat
    19621 ctgaaactgc cttcaagatt gcggcttcac tttcccttaa agaagctgct aaatcagcac
    19681 aaccagctat ccttgaacca atgatgcttg taacaatcac tgttccagaa gaaaaccttg
    19741 gtgatgttat gggtcacgta actgctcgtc gtggacgtgt agatggtatg gaagcacacg
    19801 gtaacagcca aatcgttcgt gcttacgttc cacttgctga aatgttcggt tacgcaacag
    19861 ttcttcgttc tgcatctcaa ggacgtggta cattcatgat ggtatttgac cactacgaag
    19921 atgtacctaa gtcagtacaa gaagaaatta ttaagaaaaa taaaggtgaa gactaatccg
    19981 tcctcactct agaaggaagt cacttagtgg cttccttttg tctttagaaa atacctctaa
    20041 atatggtaaa atagtagaag aataatgtga ggaaaatgaa tgtcaaatag ttttgaaatt
    20101 ttgatgaatc aattggggat gcctgctgaa atgagacagg ctcctgcttt agcacaggcc
    20161 aatattgagc gagttgtggt tcataaaatt agtaaggtat gggagtttca tttcgtattt
    20221 tctaatattt taccgattga aatcttttta gaattaaaga aaggtttgag cgaagaattt
    20281 tctaagacag gcaataaagc tgtttttgaa attaaggctc ggtctcaaga attttcaaat
    20341 cagctcttgc agtcctacta tagggaggct ttctctgaag gtccatgtgc tagtcaaggt
    20401 tttaagtccc tttatcaaaa tttgcaagtt cgtgctgagg gtaatcagct atttattgaa
    20461 ggatctgaag cgattgataa ggaacatttt aagaagaatc atcttcctaa tttagccaaa
    20521 caacttgaaa agtttggttt tccaactttt aactgtcaag tcgagaagaa tgatgtcttg
    20581 acccaagagc aggaagaggc ctttcatgct gaaaatgagc agattgttca agctgccaat
    20641 gaggaagcgc tccgtgctat ggaacaactg gagcagatgg cacctcctcc agcggaagag
    20701 aaaccagtct ttgattttca agcgaaaaaa gctgcagcta aacccaagct ggataaggcg
    20761 gagattactc ctatgatcga agtgacgaca gaggaaaatc gtctggtatt tgaaggggtt
    20821 gtttttgatg tggagcaaaa agtgactaga acaggtcgtg ttttaatcaa ctttaaaatg
    20881 acggactata cttcaagttt ttctatgcaa aagtgggtta aaaacgagga agaggcccag
    20941 aagtttgacc tcatcaagaa gaattcttgg ctccgagttc gagggaatgt ggagatgaat
    21001 aacttcacac gcgatttgac tatgaacgta caggatctgc aggaagttgt tcactatgag
    21061 cggaaggatt tgatgccaga aggtgagcgt cgggttgagt ttcatgctca tactaacatg
    21121 tcgactatgg atgctttgcc agaggtcgaa gagattgttg caacagctgc taagtgggga
    21181 cacaaggcgg ttgctatcac ggaccatggg aatgtccagt cctttccaca tggctataag
    21241 gcggctaaga aagcgggaat ccagctgatc tatggaatgg aagccaatat cgtggaggac
    21301 cgtgtcccta tcgtctataa cgaagtggag atggacttgt cagaagcaac ctacgtggtc
    21361 tttgacgtgg aaacgacggg actttcagct atctataatg acttgattca ggttgcggcc
    21421 tctaagatgt acaaggggaa tgttattgct gaatttgatg aatttatcaa tcctgggcat
    21481 cccttgtcag cttttactac agagttaact ggaattacag atgatcatgt caaaaatgcc
    21541 aaaccactag aacaagtttt gcaagaattc caagaatttt gcaaggatac ggtcctagtt
    21601 gcccacaatg ctacctttga cgttggcttt atgaatgcta attatgagcg tcatggtctt
    21661 ccaaagatta gtcagccagt tattgatacg ctggagtttg ctagaaacct ctatcctgag
    21721 tataaacgcc atggtttggg gcctttgacc aagcgttttg gtgtggcctt ggaacatcat
    21781 cacatggcca actacgatgc ggaagcgact ggtcgtctgc ttttcatctt tatcaaagag
    21841 gtagcagaaa aacatggtgt gaccgattta gctagactca acattgatct aatcagtcca
    21901 gattcttaca aaaaagctcg gatcaagcat gcgaccatct atgtcaagaa tcaggtaggt
    21961 ctaaaaaata tctttaagct ggtttccttg tctaatacca agtattttga aggagtgcca
    22021 cggattccga gaacggttct agatgcccat cgagagggct tgattttagg ttcagcctgt
    22081 tcagagggtg aagtttttga cgtggtcgtt tctcaaggtg tggatgcggc ggttgaggtg
    22141 gccaagtatt atgactttat cgaggtcatg ccaccggcta tctatgcgcc cttgattgcc
    22201 aaagagcagg tcaaggatat ggaggaactc cagaccatta tcaagagttt gatagaggtt
    22261 ggagatcgcc ttggcaagcc tgttctggct acgggaaatg ttcactatat cgaaccggaa
    22321 gaagagattt atcgtgaaat tatcgtccgt agtttgggac agggtgcgat gattaaccga
    22381 actatcggtc atggtgaaca tgcccaacca gcaccacttc caaaggctca ttttcgaacg
    22441 actaatgaga tgttggatga atttgccttt ttgggagagg aactggctcg taaactggtt
    22501 attgaaaaca ccaatgcctt ggcagaaata tttgaacccg ttgaagtcgt taagggtgac
    22561 ttgtatacgc ctttcatcga caaggctgaa gaaacagttg ctgagttgac ctataagaaa
    22621 gcttttgaga tttatggaaa tccgctgcca gatattgttg atttgcggat tgaaaaagaa
    22681 ttaacatcca tactggggaa tggatttgct gtgatttatc tggcatcgca gatgctggtg
    22741 caacgttcta atgaacgggg ttatttggtt ggttctcgtg ggtctgtcgg atctagtttc
    22801 gttgcgacca tgattgggat tacggaagtc aatcctctct ctcctcacta tgtctgtggt
    22861 cagtgtcagt acagtgagtt tatcacagat ggttcgtacg gttcaggatt tgatatgccc
    22921 cataaggact gtccaaactg tggtcacaaa ctcagtaaaa acggacagga tattccgttt
    22981 gagaccttcc ttggttttga tggggataag gttcctgata ttgacttgaa cttctcggga
    23041 gaagatcagc ctagcgccca cttggatgtg cgtgatatct ttggtgaaga atatgccttc
    23101 cgtgcgggaa cggttggtac ggtagctgcc aagactgcct atggatttgt caagggttac
    23161 gagcgagatt atggcaagtt ttatcgtgat gcagaagtag aacgcctcgc tcaaggagcg
    23221 gcgggtgtca agcggacaac aggccaacac ccggggggaa tcgttgttat tccgaactac
    23281 atggatgtct acgattttac gcctgtccag tatccagcag atgatgtcac ggctgaatgg
    23341 cagaccactc actttaactt ccacgatatc gatgagaacg tcctcaaact cgatgtactg
    23401 ggacatgatg atccgaccat gattcgaaaa cttcaggatt tgtctggtat tgaccctaat
    23461 aaaattccta tggatgacga aggcgtgatg gcactctttt ctgggactga tgtgctaggg
    23521 gtaacacctg aacaaattgg aacgcctacg ggtatgttgg ggattccaga gtttggaaca
    23581 aatttcgtac gtggaatggt agacgaaacc catccgacaa cctttgcgga attgcttcag
    23641 ctgtctggtc tgtcccacgg tactgacgtt tggttgggga atgctcagga tctgattaag
    23701 caaggaatag cggacctatc gactgttatc ggttgtcggg acgacatcat ggtttacctc
    23761 atgcatgcgg gtctggaacc taagatggcc tttaccatta tggaacgggt acgtaagggt
    23821 ttgtggctaa agatttcaga agaggagaga aatggctata tcgaagccat gaaggctaat
    23881 aaggtgccag agtggtatat cgaatcctgt gggaaaatta agtacatgtt ccctaaggcc
    23941 catgcggcag cctacgttat gatggccttg cgtgtagctt acttcaaggt tcaccatcct
    24001 atttattact actgtgctta cttctccatt cgtgctaagg cttttgatat caagaccatg
    24061 ggtgcgggct tggaggccat caagcgcaga atggaagaaa tctctgaaaa acggaagaac
    24121 aatgaagcct ctaatgtgga aatcgatctc tatacaactc ttgagattgt caatgagatg
    24181 tgggaacgag gtttcaagtt tggcaaatta gatctctacc gtagtcaggc gacagagttc
    24241 ctcatcgacg gggataccct tatcccacca tttgtagcaa tggatggtct gggagagaac
    24301 gttgccaagc aactggtgcg ggcgcgtgaa gagggagaat tcctctctaa aacagaacta
    24361 cgcaagcgtg gtggactctc atcaaccttg gttgaaaaga tggatgagat gggtattctt
    24421 ggaaatatgc cagaggataa ccagttgagt ttgtttgatg agttgtttta aaaaattgct
    24481 taataatcta ttaaaagagg ctaacgtata tccaatagat ttacattagc tttctttttt
    24541 gttaaaatag tctatggaaa gagggtgaga gtatgtcaaa gatgagtata agcatccgtc
    24601 tggatagtga ggttaaggag caggcccaac aggtgtttag taatctggga atggatatga
    24661 caacagctat taatattttc cttcgtcagg caattcaata tcagggatta ccttttgatg
    24721 ttagactaga cgaaaatcgg aagttgctcc aagcgttaac ggatttagac taaaatcgta
    24781 atatgagcca gtcttttgaa tcagtctcag atttgatgga ggacttacgt gcttaagatt
    24841 cgctatcata aacagtttaa aaaagatttt aagttggcta tgaagcgtgg tttgaaggca
    24901 gaattattag aagaagtttt gaattttctg gttcaagaaa aagaacatcc taccagatat
    24961 cgtgatcatt cattgacggc atccaagcat tttcaaggag ttcgtgaatg ccatacccag
    25021 ccagattggc ttttggttta taaagtagac aagtcggaat tgattttaaa tttgctgagg
    25081 acaggcagtc acagtgattt attttaatct attttaaggg ggttctcatg aaactaagaa
    25141 tatttgcgga agataagccg gctaagaagg tatttgaata tcaattagaa cttgctgatc
    25201 gtacaattct tctatcaaca gcactcttgt caggtgctat tgctttagcg ggattattct
    25261 ctgctttgaa agaaaaataa aaatagaaaa gagaaaatta catggtttta ccaaatttta
    25321 aagaaaatct agaaaaatat gcgaaattgt tggttgcgaa cggaattaac gtgcaacctg
    25381 gtcacacttt ggctctctct attgatgtgg agcaacgtga attggcacat ctaatcgtga
    25441 aagaagctta tgccttgggt gcgcatgagg tcatcgttca gtggacagat gatgtgatta
    25501 accgtgagaa atttctccat gccccgatgg agcgtttgga caatgtgcca gaatacaaga
    25561 ttgctgagat gaactatctc ttggagaata aggctagccg tcttggagtt cgttcatctg
    25621 atccaggtgc cttgaacgga gtggacgctg acaagctttc agcttctgct aaagctatgg
    25681 gacttgccat gaagcctatg cgtatcgcaa ctcaatctaa caaggttagc tggactgtag
    25741 cagctgcagc aggacttgag tgggctaaga aagtcttccc aaatgctgcg agcgacgaag
    25801 aagcagttga tttcctttgg gaccaaattt tcaaaacttg ccgtgtctac gaagcagatc
    25861 ctgttaaggc ctgggaagag catgcagcta tcttgaagag caaggccgat atgcttaata
    25921 aggagcaatt ttcagccctt cactacacag cgccaggaac agatttaaca cttggtttgc
    25981 caaagaacca cgtttgggaa tcagctggtg ctgtcaatgc acagggcgaa ggattcttgc
    26041 caaatatgcc gacagaagag gtcttcacag cgcctgactt ccgtcgtgca gatggttatg
    26101 tcacttctac aaaaccgctt agctacaacg gaaatatcat cgaaggtatt aaggtaacct
    26161 ttaaggatgg acaaatcgta gatatcactg ctgagaaggg tgatcaggtt atgaaagacc
    26221 ttgtctttga aaatgcgggt gcgcgtgcct tgggtgaatg tgccttggta ccagatccaa
    26281 gtccaatttc tcagtcaggc attaccttct ttaacaccct tttcgatgaa aatgcgtcaa
    26341 accacttggc tatcggtgca gcctatgcga ctagcgttgt tgatggagcg gagatgagcg
    26401 aagaggagct tgaagctgca gggcttaacc gttcagatgt tcacgtagac tttatgattg
    26461 gttctaacca aatggatatc gatggtattc gtgaggatgg aacgcgagta cctcttttcc
    26521 gtaatgggaa ttgggcaaat tagcaaaaat atcccaaaag caaattgaat tgtaagtatg
    26581 cttttgggat atttatttat aagattttat tagattttga acgattacat ttccaacaga
    26641 gagtttgaag attgtcaggt gtggaaagtc ctccttttga tacagggaca atatggtcta
    26701 tctcaagtaa caggagagat tgttcagctg tagaggcagc acagatttga caagtatagt
    26761 ggtctctttc ttttatttga gttcgaagtt tgtttgtcat cagtgatcgt tgagcttgag
    26821 cagtttgttt tgattttatt ttctttgcaa tatactctgc tgttgcttca acagtttcac
    26881 cgttaaacag aattgtcgtt ttctgagaac tattgcctcc tgcactcacg tattcaaaaa
    26941 tataagaagt gtaatcaacc tttatgtctg gtaggtggat atctaactct ttcattaaat
    27001 ctttagaaaa gtattttaaa ataaattttg gaggattaaa gtcggttttt atttgtttct
    27061 ctcgttgata aagattatca attgtgtttt ccattcgaga gatattctct ccgatttctt
    27121 caagctgttt caagctttct tcggttgcag ttattccgaa atacttacag agataatgta
    27181 taggttcttc agatgcacgt cgcacaactt gtagggaagt tgaataaacg ttactttgat
    27241 ttaaagtttt cttatgttta tctcgtttat agtcatgttg gctagtattt tcaaagtgag
    27301 ctaaatgtgc atgtttccca gtaatatcct ttacaataaa ttgatt
//
LOCUS       DAVKXA010000028        26714 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKXA010000028 DAVKXA010000000
VERSION     DAVKXA010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.028"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..176
                     /locus_tag="VW883_001244"
     CDS             <1..176
                     /locus_tag="VW883_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0274383.1"
                     /translation="NALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALN
                     IKKERTKFVLSRA"
     gene            complement(465..935)
                     /locus_tag="VW883_001245"
     CDS             complement(465..935)
                     /locus_tag="VW883_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0274384.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(901..1707)
                     /locus_tag="VW883_001246"
     CDS             complement(901..1707)
                     /locus_tag="VW883_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0274385.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(1913..2554)
                     /locus_tag="VW883_001247"
     CDS             complement(1913..2554)
                     /locus_tag="VW883_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274386.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(2551..4659)
                     /locus_tag="VW883_001248"
     CDS             complement(2551..4659)
                     /locus_tag="VW883_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0274387.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPNTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(4711..4998)
                     /locus_tag="VW883_001249"
     CDS             complement(4711..4998)
                     /locus_tag="VW883_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0274388.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPDAWARASLTKIPPTGMEYFYGFE"
     gene            5429..5749
                     /locus_tag="VW883_001250"
     CDS             5429..5749
                     /locus_tag="VW883_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0274389.1"
                     /translation="MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(5801..6388)
                     /locus_tag="VW883_001251"
     CDS             complement(5801..6388)
                     /locus_tag="VW883_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0274390.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            6630..7301
                     /gene="sdaAB"
                     /locus_tag="VW883_001252"
     CDS             6630..7301
                     /gene="sdaAB"
                     /locus_tag="VW883_001252"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0274391.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            7310..8182
                     /gene="sdaAA"
                     /locus_tag="VW883_001253"
     CDS             7310..8182
                     /gene="sdaAA"
                     /locus_tag="VW883_001253"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0274392.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            8204..8836
                     /locus_tag="VW883_001254"
     CDS             8204..8836
                     /locus_tag="VW883_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0274393.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLVPQQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            8862..8960
                     /locus_tag="VW883_001255"
                     /pseudo
     CDS             8862..8960
                     /locus_tag="VW883_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9141..10991)
                     /locus_tag="VW883_001256"
     CDS             complement(9141..10991)
                     /locus_tag="VW883_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0274394.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(11030..12190)
                     /locus_tag="VW883_001257"
     CDS             complement(11030..12190)
                     /locus_tag="VW883_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0274395.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNMLQ"
     gene            12248..13414
                     /locus_tag="VW883_001258"
     CDS             12248..13414
                     /locus_tag="VW883_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0274396.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     IGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            13554..13880
                     /locus_tag="VW883_001259"
     CDS             13554..13880
                     /locus_tag="VW883_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0274397.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            13867..14460
                     /locus_tag="VW883_001260"
     CDS             13867..14460
                     /locus_tag="VW883_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0274398.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGIEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            14453..15364
                     /locus_tag="VW883_001261"
     CDS             14453..15364
                     /locus_tag="VW883_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0274399.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQYDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            15426..16490
                     /locus_tag="VW883_001262"
     CDS             15426..16490
                     /locus_tag="VW883_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274400.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(16562..17422)
                     /locus_tag="VW883_001263"
     CDS             complement(16562..17422)
                     /locus_tag="VW883_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0274401.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(17544..18530)
                     /locus_tag="VW883_001264"
     CDS             complement(17544..18530)
                     /locus_tag="VW883_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0274402.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(18802..20277)
                     /locus_tag="VW883_001265"
     CDS             complement(18802..20277)
                     /locus_tag="VW883_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0274403.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(20361..21284)
                     /locus_tag="VW883_001266"
     CDS             complement(20361..21284)
                     /locus_tag="VW883_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0274404.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(21298..22227)
                     /locus_tag="VW883_001267"
     CDS             complement(21298..22227)
                     /locus_tag="VW883_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0274405.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(22546..22896)
                     /locus_tag="VW883_001268"
     CDS             complement(22546..22896)
                     /locus_tag="VW883_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274406.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            complement(23322..23477)
                     /locus_tag="VW883_001269"
                     /pseudo
     CDS             complement(23322..23477)
                     /locus_tag="VW883_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(23662..24273)
                     /gene="rpsD"
                     /locus_tag="VW883_001270"
     CDS             complement(23662..24273)
                     /gene="rpsD"
                     /locus_tag="VW883_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0274407.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(24468..25520)
                     /locus_tag="VW883_001271"
     CDS             complement(24468..25520)
                     /locus_tag="VW883_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0274408.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(25517..26215)
                     /locus_tag="VW883_001272"
     CDS             complement(25517..26215)
                     /locus_tag="VW883_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274409.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(26382..>26714)
                     /locus_tag="VW883_001273"
     CDS             complement(26382..>26714)
                     /locus_tag="VW883_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0274410.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         7973 a         5800 c         4861 g         8080 t
ORIGIN      
        1 tcaacgccct tcaactacac tattctaatg ccaaactgga agcgaccaat aatctcatca
       61 aacttatcaa gcgcaatgcc tttggttttc gaaactttga aaacttcaaa aaacggattt
      121 ttatcgcttt gaacatcaaa aaagaaagga cgaaatttgt cctttctcga gcttagctga
      181 cttcaaccca ctacagttga caaagagcct tatttgttcg ttagttctta ataccagcca
      241 ttgttaaacc agaagttttt agctctgcca agccacatag tgtgtttact actatgtgtc
      301 catgtcacca tgaatcgccg aacgatttaa cgagaaagta tgacttttac gtttatccca
      361 actcaattat gacatttttt tcaaaagtca atatatctca ctttttcaac gacaagaaag
      421 aggctaccaa tcgaccaacc tcttattctg aacccatcac tccatcactt tttagcttca
      481 ttcgctttct tagcgactgc aatctggtat tcgacttggt cattcccctt accggtacaa
      541 ccatgagcaa ttgtagtcgc tcctatctga tgcgctattt caaccaattt tttagaaatc
      601 agagggcggc tcaaggcaga taccaaggga tacttttgtt cataataggc atgtgactga
      661 tgagccacta gcacataatc tgtagcaaat tcgtccttaa catcaatgac ataagattct
      721 actgccccaa ccttaagagc cttatcatgg atgaaatcta agtctttccc ttcacccaca
      781 tccatacaaa ctgaaacaac atcatagtct ttctttaacc aggtaatagc aactgatgtg
      841 tccaaaccgc cagaataggc caaaattact ttttctttac tcatgttctt ttccttcttt
      901 ctatttttca atggatgctt taaaggcatc ctcaatgagt ttgtctaatt ccccagactc
      961 cttcaacttt tgaatggttt tatcgactgc ctctttcaat tccttgctat cttttttcat
     1021 ggctaccgca taggaatcat cttgctcttt ttcaaaattg aggtctgcga ttgctaaatc
     1081 aggattattt tccacaaatc ccttggcaac gggttcttca aaaataacgg catccacttg
     1141 ccctgatttt aaatctgtga ttaaattccc atttttaggc agagatacga gggaagaatt
     1201 ttgtagcaaa tctttcgcca tcgtctcttg aatcgaacct ttctgcgctc cgaccttttt
     1261 ctgcgccaaa tcgttgacag actgataagt ggctaaatca gattttttga caatgagttt
     1321 attttttgca gtatagtagg gagttgaaaa atcaaacacc ttgctccgtt catctgtctt
     1381 agaaacacct gatatggcaa ggtcagcttt tcctgattga acgctagcca gtacattgtc
     1441 aaaactcata ggagatagtt ccaattcgac acctagttct gttgcgatag ccttggctaa
     1501 ttcgatatct gaacccacaa tctgattttt cccatcaacc actttttgat attcaaatgg
     1561 agcaaaatct ggattgaggg ctacaaccaa ttttcctttg gacttgatgg cttcaattcc
     1621 agccgattga ttgttactac aagcaaatag tagggggagc atcactaaac caaacatcgt
     1681 catcaacacc ttcttcatct tattcataac aaagcctcct ttatgtttat tcttttttat
     1741 tgtataaata atactcctat actcatcctt tgtcaagcct aaattgaaaa aattttcaat
     1801 ttgaaacaaa aaaacctaga aatactacat aaaatgtcat tcctaggcgt atttatgcta
     1861 tttttctcta gaaaacatga gtattcagcc agtcaaaagg agctgaatga actcattttc
     1921 cctcgcccaa ttcaatgaca cgatgacatt gttgggctac ataagcatcg tgggtcacaa
     1981 taatgactgt tttcccttct cgattcatct ctaagagaaa cttcaagacc aaatctctat
     2041 tttcaggatc cagcgaacct gtaggttcat cggctaaaat cagctggctg ggttttaaga
     2101 tggctctagc aactgcaatt cgttgttgtt cgcccccaga caactcggag accctttgat
     2161 gcaaagtagc tgacaaacct actctctcta aaatctcttc cacctttttg agtttgtctt
     2221 tcttaggcaa tttcacatat ttcagcgcca gcatgagatt gtactcgacc gtttcatcat
     2281 caatcagggc aaaattttga aacagataag agatatgttc acggattatt gtttgcgact
     2341 tagcagaatt aaccgctaga tttgtctgac caaaaatctc ataccgtccg ctataatcac
     2401 catctatcaa acccaataaa tttaacaagg tcgacttccc actaccactc ttaccaacaa
     2461 tagctaccaa atccccctga tcaatcctga gagataagtt atccaaaatc acttttcccc
     2521 caatggtttt ggtaatattt ttcaactcaa tcataagatg ccccctttca ataactctac
     2581 tagacttctt ttctccatcc tagaagctaa gcctagcaca aatagtatat ccagacatgt
     2641 aaaacctgca aacagtagaa gtggtaagaa cgcatgggca aagaaaatca agactagaag
     2701 agggaaacta tagcccagca agagcagaac gaggagagga cggtagcgat cgaccagttt
     2761 ccaccccata aacttcttgg taatgatatc cctgcgcttc aataagaaag ttgttactag
     2821 taagaagtag gaaatcatca tgctaaggag accaaacaaa gcaaagagta ggttaaaatt
     2881 ccgaacagca tctcgataag aatccacttt ctcttgttga atggcttgaa tagatgaaaa
     2941 ttttaaataa tttccatctg acaatttctc aactaactct gtaatctctt tttgatgttg
     3001 aaccgtattt tcaattttaa tcggattatt taagccagtt gttgacaggg aggctttctc
     3061 atcccacatc atatcagaat cattgaccaa gctaataatt ggattggaga gattttcctt
     3121 tcgcttatca ctatatggga aaaatgacca atctccttca taataggcaa tctcgacatc
     3181 catctcctct atcgttcgtt tttgctgctc ttcatacttc atcgaatgaa aggcaattaa
     3241 cttccccaag agctgatttt tatcttcttc acctttcgta cttgctggca tcaaaataac
     3301 ttttttaata ccggtatttg gtagcttgaa tcccttgctc tttagaaaat tgcgattggc
     3361 atagtaaaca tccaccgtat ctgttaactg atattgctga atctgttctg attggacaaa
     3421 attttttaca ggaagactgc tactctgcac atagcccgcc tgcgtttttt ctaccaaatc
     3481 ctgataaaat cgatagaaat aatctgtaga tttccctgac cctgctagct cttcttgcca
     3541 cagattatca ttgagtttga aggtttctaa ggtcaggtaa ttaccttgac ttacccactg
     3601 ttgctgataa gcaagttctt tgttttcttg ttctaaactt ctgcccaccc caatcagtaa
     3661 ggccgtcagt aaaatagttg tccctatttt catcacataa ttgaagataa gaccaaattt
     3721 gaaagatgaa aaacctttca gcagagagct gattgtcatt ttttggatta agaggtaagt
     3781 caaccaactg ataaagagat aaagctgcaa cagcaaaaaa tgagacaacc acagcatagg
     3841 aaacaaatct tttggcttat aatcaagcaa gaaaaacacg cctagattga tcacaagagc
     3901 cccacctagg aggaggtaaa ggttgccttt tacaacatca gctaaaacag ccctatcttg
     3961 aaaaccaagt aatttttgta ccccaactct tttcatctcc atcatcggtt gatacactgt
     4021 cactaacaca agaagcaaaa tagccaagac aaaaacaatg gcagataaaa gcaaatctcg
     4081 atttatgact tccactgcac ttttgtaggt cggctctagc aaggtagcct ggtctatctt
     4141 gaaaaaatcg ctccatttct gtacaatcct atccttgtcc atctcttgtg tagaagttat
     4201 cgtatagcga ccatttaaac tacgagatgt atccttgata taggtttgaa aagtcataag
     4261 ctgaataggt ttggctttta gaaaggtcgg aatcgtacca agtttattgg aaatttcttt
     4321 attactatag actccttcac catctgtggt aaaatcaaga gaagaaatcc caaactcttg
     4381 gtaggggaag gtatctttat caaaaacacc agacttgacc acctcatcac cactgtctgt
     4441 tttgatgatg gagactttat actcctttga tacatcctca aaaaatcgaa gaacagacgc
     4501 tgcaggttcg ttaatatctt tcaaatacaa atccaaagaa tctacagtct ttcccatttc
     4561 ttgaatccga accacttctc gtgtatagtt tacattaaaa acaaaaaaag tggtacacag
     4621 aagcaggagt aacatacaga aattactgat ttttttcata aaagtgcctc cactacagtt
     4681 ttccctctcc aaataggaga gggaagaatt ttactcaaat ccatagaaat attccattcc
     4741 tgttggcgga atcttggtga gggaagctct agcccatgca tcaggttttg cataatcctt
     4801 agaggttcta cccccatgtc taacagttgc tgtatgatat cgagtagaat gtaagtaatc
     4861 agaatatcca aaagttcctg tccaacctac tccatagttc cattgaccac cctcaaccca
     4921 tactgctaaa gcatttgtag tagcaagtat accacatacc attaaagatg caacaccaat
     4981 tttaactaat tttctcatga tttatttctc ctattatcga gagctgttcc gtaaaaacag
     5041 ctatagtaat ttatcaacaa gtatcgtagt ccattggact caccttcctt ctatctcatt
     5101 tcatttttta acaacgaact tactcttaac cgggagaatg gtgcgcttct gtatcaggtc
     5161 cttgaacaac cagagtagta ttaagcaaac tctaactatt actcaagaat cagtccaata
     5221 aacaatatgg atagcgcttt caaattttta aactcctatc ccgtcctttt atctatataa
     5281 taagcataag cgaaaatata ataactgtca agtatctgaa gtgaatttta taaaaaaatt
     5341 acaagccaaa tttgtaaagt ttacactaag ccgctagggc aatcgtctat cagaatgtcc
     5401 gtttatttgt caataatccg agaaaatctt gcaacgctta gaagtctata aaaactatca
     5461 acgtttatat gacttgcgaa tagcaatcct gctcaacctt tccacactct atctatacaa
     5521 tcaagataaa aacatgtgta agcaaatctg ctacacttta ctggaggacg ccaagaataa
     5581 gaaaagctac gataggctgg ctatctgcta tgtccgtatt gggatttgta cagataatgc
     5641 taaacttatc caaaaagggt tctcccttct ggagctaacc gaggaaactt ctatgctgtc
     5701 tcatctcaaa aaagaagtag agatctatta ccaagcgaag gaaagataaa aaagccgagg
     5761 gatttcctcg actctttaca tattatttgt tcgttagttc ttaataccag ccattgttaa
     5821 gccagaagtt tttagcagca gtccatgaac cgtaacgtcc tgcaacgtag gcatctgcta
     5881 cacgttcttg gttttcagct gagtagtcac cgttcaggta tgaatctgtt aattggtaac
     5941 gtccgatata acgtccattt gtagctgtat agctaccacc tgattctttt tgagcgatcc
     6001 attctttggc ttctgcttca gatccgctta cagttgaaac aactgtttca cttactactg
     6061 gagtttctgc tactggagct gaaacagttt catcttgagc ggctggtgcc gcataagtag
     6121 ctggcgctgg tgttgcaaca ggcgctacag ggccatcgat aaccaactct tgaccaacat
     6181 aaatcaaatg aatgttatca atgtggttgt tttctgccaa tttttcaact gttgtgttgt
     6241 gagtttcagc gatttctgaa agtgtatcac cttctttaac agtgtaagtt gatgattctt
     6301 gagcagatac aaatgatgga gcaaatactg caaacaaggc agctactcct gcaagagttg
     6361 ctttaatctt tttagttatt gatttcatat tcgaaaattc tccttctttc tatagttcta
     6421 tcataccctt taaatattac cgtttcttga cacttttatg tagaaatatt acaaaattat
     6481 tttttatttc cctaaataag gtgttttttg tcataaaaga tactattttt atgctatttg
     6541 aggtattaga aaggttttca tccacaatta aagccaagcc cctcattctt tgatataata
     6601 gagataagaa tttttataag gggaaactga tgaaatcact tcgttttcaa tctgtctttg
     6661 atatcatcgg accagttatg attggcccat ctagtagcca taccgctggt gctgttcgta
     6721 ttgggaagat tgtctcttcc atttttgatg atactccgac agaagttgaa ttccaacttt
     6781 ttaactcatt tgccaagacc tatcgtggtc acggaacaga cctagccctt gttgcaggta
     6841 ttttaggaat ggatacagat gatcctgaaa ttccaaatag tctggaaatt gcccacaagc
     6901 gtggtatcaa gattgtctgg accattcaga aagacagcaa tgcccctcac cctaacacca
     6961 ctaaaattac tgttaaaaat gcccacaaga ccatcagcgt gactggtatt tctatcggtg
     7021 gaggaaatat tcaggtaacc gaactcaatg gttttgccgt ctctctcaat atgaatacac
     7081 cgactatcat catcgttcat caagatattc caggtatgat tgcccttgtt acagaggcgc
     7141 tttcccgcta tggtatcaat atcgcccaga tgaatgtcac tcgtgaaaaa gctggtgaaa
     7201 aagccattat gattatcgaa gttgacagtc gcaactgtga tgaggctatc gaagaaattc
     7261 gaaaaatccc tcatctccac aatgtcaatt tctttaaata ggaggaagca tgttttattc
     7321 tatcaaagaa ttggtcgagc aagcagatct ggactttcaa ggaaatgtcg cagaactcat
     7381 gattacaaca gagtttgaat tgaccggtcg cgaacgtgaa gaagtcttcc ttctcatgga
     7441 acgcaatctg gaagttatga aagcctctgt ccaacttggc ctcaatgaaa ataaatctcg
     7501 tagtggcctg acaggtggag atgctgccaa attggaccac tacatcaaaa acgaaaaaac
     7561 tttatcagat tacacgattc tctctgctgc ccgaaatgct atcgcagtca atgaacacaa
     7621 tgctaaaatg ggcttggtct gcgctactcc taccgcagga agtgccggtt gtctcccttc
     7681 cgttctcact gctgctattg aaaaattaga cctcagccac gagcaacaat tggatttcct
     7741 ctttgctgct ggtgcctttg gactagtcat cgcaaacaat gcctccatct caggtgctga
     7801 gggtgggtgt caagctgaag ttggttcagc ctctgctatg agtgctgccg ccttgactct
     7861 ggctgcaggt ggaacacctt atcaggccag tcaagctatt gcctttgtca ttaaaaatat
     7921 gctaggcctc atctgtgacc ctgttgcagg tttggtcgaa gttccctgtg tcaaacgtaa
     7981 tgccatggga gctagctttg ctttcatcgc agcagacatg gccttggcag gtatcgaatc
     8041 taaaatccct gtggatgaag tgatcgatgc catgtaccaa gtaggagcaa gcatgccaac
     8101 tgcctttcgt gaaacagctg aaggtggact cgctaccacc cctactggtc gtcgcctcca
     8161 aaaagaaatt ttcggagaat aagcttatca aataggagaa accatgacct ctatcacagc
     8221 gatttttttc gatttggatg gaaccctcgt tgatagttct atcgggattc acaatgcctt
     8281 tacctatacc tttaaagagc tgggggtgcc tagccctgat gctaaaacta ttcgtggttt
     8341 tatgggacca cctctcgaaa gtagttttgc gacctgcctg tccaaagacc aaatttctga
     8401 agccgtgcag atatatcgtt cttactataa ggcaaaaggc atctatgaag ctcaactctt
     8461 tcctcagatt atagacttgc ttgaggagtt atcgagcagt tatccactct acatcaccac
     8521 gacaaagaat acatctactg ctcaagacat ggcaaaaaac ttggaaatcc atcatttctt
     8581 tgatggcatt tatggttcta gccctgaagc accccataag gcagatgtca ttcaccaagc
     8641 cttgcagaca catcaactag tccctcaaca agccatcatc atcggagata ccaagtttga
     8701 tatgctggga gctcgagaaa caggtattca gaaattggcc gtcacttggg gatttggaga
     8761 gcaagcagat ctactaaact atcaacctga ttatatcgct cacaaaccct tagaggtttt
     8821 ggcgtatttt caatagcata gactgggtaa caattccatt tcagaagaaa atgaagtaat
     8881 actcaatgaa aatcaaagag caaactagga aactagctgc gggctgctct aaacactgtt
     8941 ttaaggttgt agatggaact gacgaagtca gctcaaaaca ctgttttgag gttgtggata
     9001 gaactgacga agtcagtaac catacctacg gcaaggcgac gttgacgtgg tttgaagaga
     9061 ttttcgaaga gtataagtct ctacataata aaacgcatat taccaaggtt gtgtaacttg
     9121 atactatgcg tttttctttt ttattcaatg tgggttgttt gattagcaaa ggcgataata
     9181 gcttgcttca actcatctcc actgagagtg cggaactctc caatcttttg attgatggat
     9241 tctaaaggca tgacattaac cttaccaacg aaaatcttat ccataacttg attatcaacg
     9301 agttcggttg ataccaagag ttcttcgtag agtttttcac ctgggcggat tccaacttca
     9361 acgattggaa tttcactttc agtgtggcca cttagaagca ccatcttctt ggccaagtca
     9421 taaatcttga ctggtttgcc catatcaagg ataaagactt ccccatcttt ggcataagca
     9481 ccagcatgga taaccagacg actagcttct ggaatggtca taaagtaacg ggtcatgcgg
     9541 aagtctgtca ccgttacagg cccaccttca gcaatctgac gttcaaagac tggaatgaca
     9601 ctaccacggc taccaagaac attcccaaaa cgaactgcac agtaggttga ttggctacgt
     9661 tggttaaagc cagtgacaat caactccgcc acgcgcttgg ttgctcccat aacatttggt
     9721 ggattgactg ccttatctgt cgaaatcata accatcttag acactttagc ttcatcaaca
     9781 gccttagcaa cattgtaagt tccacggata ttgtttttga aggcttcttt tggattgcgc
     9841 tccatcatag gaacatgctt gtgggcagcc gcatgataaa caatagcagg tttgtactgc
     9901 tcaaagactt gcaacaaacg atcatagtct tgaatgtccg caatcacagg tacataatca
     9961 atcccttgga acttacgaat caattcatga taaacaaggt agattgagtt ttccccatga
    10021 ccgagcaaga caatgcgttc aggattgaag cgactaactt gacgacagat ttcagaaccg
    10081 attgaacctc cagctcctgt gactaagatg gtcttacctg tcagttctgc acccagacgc
    10141 gattcgtcaa gacggatttc ctgacgaccc aaaaggtccg taatatcaat tttttggaag
    10201 ccagtacctg cttggtgaag gccctgaaca acagtttcaa ccttaggcat cttgtaacat
    10261 ttgacaccca gcttattaca catctgcaag atacgctcat attctgacgg atccagcgac
    10321 ggaatcgcaa cgatgacacg ctcgatttga tggcgtttgg ctaattcagg cagattgtca
    10381 taagagccca aaacaggaat accaccaagt ttttgaccct ttttcttaga atccttatcc
    10441 aaaataccga ccagttctaa ttcactggtt ggatgttggt aactatccat aaagagagcc
    10501 ccaccatcac cggcaccaat caagaaggtc cgacggtgtt ctccatcacc actacctttt
    10561 ttgcgtctgg agtagattaa ctgccaagta atccgtggca ataaaatcaa gaaggtactc
    10621 aacaagataa agagaatgat gaaacggatg gagaagagtg gcaagaaggc ataacagata
    10681 ctatatgaca agacactgct agcagtcaca ccaaaaaaga ttttcatgaa atccgtaatc
    10741 ttgctgtaac gactaatgct cgcgttcaac ccccaaaaac caatcatcaa ttgatagaac
    10801 aagaaggcca aactcgtata gataatgtag tcaacaggtg ctggattaat cagcccataa
    10861 aataaaatat aagatacaat gatggaaacc accatactga aaatatcaaa tattccccaa
    10921 aaaacctgct tttgttgttt atttaaaatt tccaccagat caatcacata atctgttagt
    10981 tttttattca tagaaatcta ctcctcctta aaagagtttt actatattgt tattgtagca
    11041 tattttgatt tatttggctt attttatcca aataaattat tgttctcttg tactccttct
    11101 tccatttaaa tcctctaatt aaacctacaa tcgtcccaag gccataagca aagtgaatgg
    11161 aaaataaaag aaagggcatc acaattagaa atccattttt atgttttaat aaagtcagca
    11221 aagtgagtaa tgacaaaagt agaaaatagg cacctaatag taaagttatg aatacgaatg
    11281 tgatcggtaa caatgctaga ctaaacacaa gactcaaaac aaataaacaa ggaacatagt
    11341 gaaataatga taaacactta aactgaacat gacttgtcaa gccaatccac aaaccatttg
    11401 aatacttttg atgcagcatt ttcttgaatg ttggtcgaat atactgataa gatagaatac
    11461 ttgggctata gcggatttta taaccatatt ctcgaattct ataatgaata tcattatctt
    11521 cagttcggcc aagttgctca tttactaaac caaccttctg gaaaacctct cgtttataca
    11581 ttccatgaaa aatagaagaa acatatctat cctcagaact atttcgataa ttggcaatgc
    11641 tactgccaaa catattttcc tcaacaagat gcaaggtctc tgcccatttt ccttttcctt
    11701 cgacaatcgt cggtctaggc cccccacaga caaattcacc ttgttgaata atagccacat
    11761 tgttcattac aaaagtctca gtaacttttg aatgagcatc aatttttaaa ataaggtccc
    11821 ctacagaatg tttaactccc aggttaaaac cactagcttg atttttctta ggattgttat
    11881 acaatctaat tgagttaaac tctgtatctt cctttataaa ttgctgaatg atagctgtgg
    11941 tcccatctgt ggacatagca tttataaata gaatttcaat attctcttta ggataggttt
    12001 gattttttaa gtcttcaatt agaccaggca gatatttttc ttcattgtat gcactgatta
    12061 caatggatac gagaagactt tcaacatttt gagtcactac tactctcctg aatttttcct
    12121 tccaccattc tatcataatt ttcaagactt tcccattttt atcttgaaag ccagaaacct
    12181 tacttgacat tatagtgaaa aagccttaaa ataagctgtt attaaaatca gctagaagag
    12241 gtattatatg aaaaagcaat cactcttttt tgttccaggt attatcctga ttggtgtttc
    12301 cttgcgaact ccttttactg ttttacccat tattttggga aatatttcgc aaggtctgga
    12361 ggtagaagtt agttcgcttg gtgtcttgac cagcctgcct ctccttatgt ttaccctctt
    12421 ttcaccattt tctacccaac tggctcagaa aatcggcttg gagcatctct tcacctacag
    12481 cctcttcttc ttgaccatcg gctcacttat tcgactaatc aatctgcccc tgctctatct
    12541 aggaaccttg atgattgggg caagtgtcgc agtcatcaat gtcctgcttc ctagtcttat
    12601 ccaagccaat caaccaaaga aaattggttt tctgaccacc ttatatgtaa cgtctatggg
    12661 gattgcaacg gctctggctt cctatctagc tgtgcccatt acacaagcca gttcttggaa
    12721 aggacttatc ctcctcctca cgttactctg tctagcaact tttttggtct ggctcccaaa
    12781 tcaccgctat aatcatagac tagctccaca aaccaaacaa aaaagtcaaa taaaggtcat
    12841 gcgtaataaa caggtttggg caattattat cttttcaggt tttcaatcct tgatctttta
    12901 caccgccatg acctggttac ctaccatgtc tatccatgca ggtctatcca gtcacgaagc
    12961 tggcttgctg acttctatct tatctctgat tagcattcct ttttcaatga ccatcccaag
    13021 cctgacaacc agtttatcta ctcgcaaccg tcagctcatg ctcactctgg tttcactagc
    13081 tggtgtggtc ggcatttcca tgctcttttt cccaatcaat aatttcattt actggcttgc
    13141 catccatctc ctcatcggaa ccgcaaccag cgccctcttc ccttatctca tggtcaactt
    13201 ttcactcaag acaagcgccc ctgaaaagac agcccaattg tccggtctat ctcaaacagg
    13261 aggctatatc ctagcagcct ttgggccaac cctctttggt tacagttttg acctgttcca
    13321 ctcttgggta ccagctgtag ctgccctctt gctcatcgat atcctgatga ctgtggccct
    13381 ctttacagtg gacagagcgg ataagatcct ttaaacttct agttttagct agaagttttt
    13441 ttatatataa aaattttaca catttctctt gacagggctt tcttttagat gtacaatgta
    13501 tgtgtagaaa aattatatat aaaaatctta cacattagaa aaggaggttt cccatgtact
    13561 ttccaacatc ctctgccttg attgaatttc tcatcttggc cgtactggag cagggtgatt
    13621 cttatggtta tgagattagc caaaccatta agctgatcgc taatatcaaa gaatccacac
    13681 tctatcccat tctcaaaaaa ttggaaggca atagctttct gacaacctat tctagagagt
    13741 tccaaggtcg catgcgcaaa tactactcct tgacaaacgg tggtatagag cagctcttga
    13801 ccctaaaaga tgaatgggca ctctatacag acaccatcaa tggcatcata gaagggagta
    13861 tccgccatga caagaactga atacctgact cagctagaac tctatctcaa gaaactacct
    13921 gaagctgacc gtatcgaagc catggactat ttcagagagc tctttgacga tgctggaatc
    13981 gaaggagaag aagaactcat cgctagtttg ggaactccca aagaagcggc ccacgaagtt
    14041 ctatccaatc ttctcgataa aaaaatcaat gaagcacccg ctcaaaaaaa taaccgacaa
    14101 attttacata tcgccttgtt agccctcctt gcagcaccta tcggcattcc tctgggaatc
    14161 gccatcctcg tgaccctgtt cgcaatcctt gtagccgctt tgactgtcat tctggctttc
    14221 tttgcagttt ccatactggg tatcatcggc ggattcctat ttttagttga aagtttcact
    14281 gtcctcgccc aagccaaatc agcctttatc ttgatttttg gttctggttt actggctatc
    14341 ggtgcttctt cgctagtttt acttggcatt tcctatgtaa ctcgcttctt cggtctactc
    14401 attgttcgtc tggtacaatt tgttcttaaa aaaggaaaga gaggtaatca gcatgcgtaa
    14461 atggacaaaa ggatttctca tctttggtgt ggtgactacc gttatcggct ttatcctgct
    14521 ttttgtaggt atccaatatg acgggattaa gagcctactt tccatgtcca aagaacctgt
    14581 ctatgatagc cgtacggaaa agctaacctt tggcaaggaa gtcgaaaacc tagaaattac
    14641 tctccaccaa cacacgctga ccatcacaga ctctttcgat gatcaaatcc acatttctta
    14701 ccatccatct ctttctgctc accatgatct tatcaccaat cagaacgata gaactctgag
    14761 tctcactgat aagaaactgt ctgaaactcc gtttctctct tctggaattg gtgggattct
    14821 tcatatcgca agtagctact ctagtcgttt tgaagaagtt attctccgac taccaaaagg
    14881 gagaactcta aaagggatca acatctcagc caatcgcgga caaaccacca tcataaatgc
    14941 tagccttgaa aatgcgaccc tcaatacaaa cagctatatc ctccgaattg aaggaagtcg
    15001 tatcaaaaac agtaaactca caacgcccaa tatcgttaat atctttgata cagttcttac
    15061 agatagtcag ctagagtcaa cagagaatca cttccacgct gaaaatatcc aagtccatgg
    15121 caaggttgaa ctgactgcca aagattatct cagaatcatc ctagaccaga aagaaagcca
    15181 acgaattaac tgggacatct caagcaacta tggttctatc ttccaattca caagagaaaa
    15241 gcctgaatca agaggtacgg aattaagcaa cccttacaaa actgaaaaaa ccgatgtcaa
    15301 ggatcaactc attgcgagat ctgatgataa tattgatcta atatccacac caagcagacg
    15361 ttgacaaaaa cgcttacatc tgctactatg gaagcatatt tatctaacca aaaggaggtt
    15421 ctaccatgaa acaagaatgg tttgaaagta atgattttgt aaaaacaaca agcaagaaca
    15481 agcctgaaga gcaagctcaa gaggttgcag acaaggctga agaaacgata gccaatctcg
    15541 atacaccaat tggaaaaaat actcaagtag aggaggaagt ctctcaagct gaagtcgaac
    15601 tggaaagcca gcaagaagag aaaattgaaa ctcctgaagg cggtgaagcg agaacagaaa
    15661 tagaagaaaa gaaggcatct aattctactg aagaagagcc agacctttct aaagaaacag
    15721 aaaaagtcac tatagctgaa gagagccaag aagctcttcc tcagcaaaaa gcaaccacga
    15781 aagagccact tcttatcagt aaatctttaa aaagtcctta tatccccgac caagctccaa
    15841 aatctaggga taaatggaaa gagcaagtgc ttgatttttg gtcttggcta gtagaagcga
    15901 tcaaatctcc tacaagtaag ttggaaacaa gtatcacaca cagttacaca gcctttctct
    15961 tgctcattct gttttctgca tcttcctttt tctttagtat ctatcacatc aaacatgctt
    16021 actatggaca tatagcaagc attaacagtc gcttccctga gcagctagct cctttaactc
    16081 ttttttctat catctctatc ctagtagcga caacactctt cttcttttca ttcctcttgg
    16141 gtagtttcgt tgtgagacga tttatccacc aggaaaagga ctggacgcta gacaaggttc
    16201 tccaacaata tagtcaactc ttggcaattc caatcttcct cactgctatt gctagtttct
    16261 ttgctttctt tgatagccta cgatttacag ctctcttgtg tgtgattagc attggaatca
    16321 ttctgcttgc cagtctccat atcattacaa gaccaagtca agcaagtgaa accgactcct
    16381 tctatcaatt attcttgtct gtccttgtga acggagttat tatcctcctc ttctttgtag
    16441 ctgaagtggc actgattgga gattatcttc gtatcttggc ctttctttaa aattcaatcc
    16501 tgtcatcctt ggcaggattt tttctatgtc aaaaaagcaa gtcgattgac ctgcttctgc
    16561 tttacttttc ttgtgctaat gttttaaaat ctttgtctaa tatgggttgc acttctattt
    16621 gattggcgtc tagttggtgg taaaaagatg ggggtaatac ctctaagaat tttgcatagt
    16681 ccaagcgagc tatggattca tagtcttctg gtttagagcc gtctcctgtg atttgaacca
    16741 agtcaatctc ccactggact tccttatcca ccaattgctc aatataggct gcaggaacaa
    16801 acggttctct cggtaaaact gtcttgactc cttgagctaa atggtaaacg ccatgcactt
    16861 ttccttctcc atcctgatag aaggaaactc ttgcaaagta ggcatctgtc tcttgaaccg
    16921 cacgcacacg cgcttcaaac tgagccaagc catctgcctc taaaaagctt ttcaagttct
    16981 cacgactaaa gaaaatagga ttaaaaattc cttggcaaat cgtaaaacga gctacagggt
    17041 ctgctagata ggcttgaata cttgcttgga aataagcttc aaaatcaaaa ccatctagcc
    17101 cttcaatatc agtccctgta taagcaagca aagcatctaa aaatgacttg ataatctgcc
    17161 agtctgtctt tgttagtagg tcaggaagat cgacacggta agccttttga ccatcagcat
    17221 aactgacctt aaagagaaat tgtgattgcc ccactatcgc acactcaata tactcgagac
    17281 gattaagagg ctgacgaaga tagactacat catagctatg tgactccaaa ccgtctagca
    17341 aggccaagat cgacttggca ttcaaaatct cttgttctcc taaaatgctc tgtttatttg
    17401 gaataaaaaa tgtttttgcc ataactggac tcctttgaaa tcgtttacat acagtatacc
    17461 ttattttcct gaaagataca aaaacaaact ttagattttt gagtacaaag catagaaaaa
    17521 cagcccctga ggactgtttg atcttataca gtagctgcct gatccaagct ttcaccgata
    17581 gcggctaggc gctcaatcac ttcagcttgt gtcaattcat tttttgaaac atagcggtta
    17641 cgtgggtgaa cacggcactc gtgtgagcat ccacgaaggt acttgtcttc attttcttct
    17701 gatgtcaaga tacgacggtt acagaaggga tttccacagt tgacataacg ttcacatggt
    17761 gttccatcaa accagtcttt ccctacgatg gttgggttga catggttgac atcaacggca
    17821 atacgctcgt caaagacgta cattttccca tcccaaagct caccttgaac ttctgggtct
    17881 ttaccgtaag ttgcgattcc tccgtgcaat tggccgacat ctttgtagcc ttcacggacc
    17941 atccagcctg agaatttctc acagcgaacg ccacctgtac agtaaaccac gacacgcttg
    18001 tccatgaatt tttccttgtt atcacggacc cattgtggta actcacggaa gttgcgaata
    18061 tctgggcgaa tagccccacg gaaatgtcct aggtcgtact cataatcgtt acgtgtgtca
    18121 aggacaacgg tatctttatc aagaagcgct tctttgaact cttttggaga caagtaagca
    18181 cctgttgttt caagtgggtt gatgtcattg tcaaagtcgt tgtcttccaa accaaggtgg
    18241 acaatttctt tcttgtagcg aacaaacatc ttcttgaagg cttgttcatt ttcttcgtca
    18301 atcttgaacc agagttcttc cattcctgga aggctgtgaa cgtagtccat gtatttttga
    18361 gttgtttcat agtcacctga aactgttccg ttaattccct cgtcagcgac taggatacgg
    18421 cctttaaggc cgattgattt acagaaagcc aagtggtctg cagcaaattg ctctgcattt
    18481 tcaattggag tataaaggta gtaaagtaag acacgaatat cttttgccat aagatttgtt
    18541 ctcttttcta ttcttaaatt ttctaaattt tttatttatc tacactagta tacctgcttg
    18601 agaaaacgaa tgcaatttat ttgactggaa attgtagagg gttctcgaaa tttcctgaat
    18661 ggttaaaata aggacaagag aaaacatgga tatctatatc cttgtgccaa aaaaaccact
    18721 gccctcccca gaccaacctg aggaaagcgg tgattcttat tttaggagtt aggaatgaat
    18781 acacgaaatc aatttagctg attatttttt gtttttcaag aattcatcgt attgtttttg
    18841 catttcgttc aatacttttt cgtaggcacc ttcagatttc aatttttcca tcaattctgg
    18901 aatcgcttta tctgggtcta cagtaccagt gttgatagct gtatcaaatt gttgcattgt
    18961 gttagcaata gctgagattt cagatttcac attgtcagta ttgaagataa atccaagcgc
    19021 tggagattct ttagcttctg ccaattcttt cttagaattt tcgatttgtt ggtctgtaac
    19081 gttttcgttg atgtaaagga tccagttgtt accagtgttc catccaccca tgtgagtgtt
    19141 tcctttgtag ccatcaagaa cgcgaacacg gttttcttta ccttcaattt tttcccagtt
    19201 cttgccttct ggaccgtaaa caagaccgtt caaaagttct gggttcgtat tcaagaggtt
    19261 caagatttcc attgattttt ctttgttctt agagttgttt gagatgacaa agttagcaac
    19321 ttgtgttgtt tggtttttct tgatgaagtt agtgattggt ttgatttgga tatctttgtt
    19381 ggcaacacgt gaaagcaagc tgttaccgta gtcagctggt cctactgttt cttcacgaac
    19441 gaaccaagta tcttgttgaa ggtcaaatga agtgtcactt gttgcgacgt cttttggaat
    19501 gtagccagct tcatagaatt tgtgaagagt cttcaagtgt tctttgaaac gaggcacttc
    19561 gtaacggttt acaactttag tagtatcgcc ttcaaggtca ataacgaatg gaagcccgtt
    19621 tgctactggg tagtcaaagt tatcagatgg gatgaaaact ttaccaatag caaatggtac
    19681 tacgtctgga gctttttctt tgatttgttt caagactggc tcaagagttt cgtaagaagt
    19741 aacacctgaa atatcgatac catatttggc aaggagagtt ccgttgaagg caaagttttg
    19801 agatgatgct acgttggctg caactggtac agcgtaaatc ttaccattta cagtattacc
    19861 cttgatataa gctggatcaa gtgccttgta aaggtcttta ccttcttttt tgtacaattc
    19921 tgtcaagtca gcataagcac ctttttgagc atttacaata tagttatctg caaaggcgat
    19981 atcatagttt tcaccagatg atgtgataac tgacattttc ttaccatagt caccccagcc
    20041 aaggtattgg atatccaatt tggcaccaac tttttcttcg atgattttgt tggcatttgc
    20101 taacaattca tccaagttat ctggtttgtc accgatttgg tacattttga taacaggttt
    20161 gtcacctgaa tcagcagctt ttttgctgtt acctgtcaaa tttccacaag cagcaagacc
    20221 tgcagccaaa gcgactacac tagcagatgc aaaagcatat tttttccagt ttttcatgat
    20281 aaaaactcct ttttttattt ttaaacttat aaacaatgta atgatcttaa cttcacgcaa
    20341 gggaagtttg gaaacaagtg ctattctttc acaccaccga tagtcaaacc ttttacaaag
    20401 tagcgttgga agaatggata caaaattgcg attggaaggg ttgctaccac aaccatggcc
    20461 atacgacctg tttctttcgg tagagcaact cccagttgac cagtcaagcc gaccgctttg
    20521 gcaatgtagt ccatattttg ttggatttgc atgagcaaat attgcaatgg atacaagttg
    20581 tcactcttga tgtaaagaag ggcgttgaac cagtcattcc agaaaccaag agctgtcaaa
    20641 agcgtgatgg ttgcgatacc tggtagtgac aatggcaaac agatttggaa gaaaatccgg
    20701 gcctcactgg caccatcgat acgagccgat tcgagaatgg cttctggaat ggtcttcttg
    20761 aagaaggaac gcatcaagat gatattgaat ggtgagagaa gcattggaac aatcaaggcc
    20821 caaacagtgt caccaagctg aagtacacgg gtcaccatga tataacctgg taccaaacca
    20881 gcgttgaaca acatactgag aaggacgaag atggtaaaaa atctgcgata cttaaaggtt
    20941 gtccgtgaaa tagcgtaggc ataggttgtt gtgataaaga catttgtcaa tgtcccaact
    21001 acggttacaa agacagagat gaagagggct tgtaggattt tatccttaaa ctgtgccaaa
    21061 aactcaaaac cgtctaagcc aaattgggat gggaagaagc tatagccgta ttggaggagg
    21121 cttttctcgt ctgtcactga aataatgata acgaatacaa aaggtaggat acaagagagg
    21181 gcaatcaaac ccgaaatgat actgaagaag atatctgctt tcttactgaa ggagtgaatg
    21241 ccgacattat caattttttc ttttttaatt ttcttttttg ccatattctc ctcctttcta
    21301 gaacaaagct gagtttggat cgactcgtct tgcaagcaag tttgatagga taaccagaat
    21361 caaaccaaca acggattggt aaagaccggc tgctgcagcc ataccgatat ctgctgtctg
    21421 agtcaaacca ttaaaaacat atacgtccaa aacgttggtt acattgtaaa gctgaccagc
    21481 attgtgtggg atttgataga agagaccgaa gtctgcgcgg aagatatttc cgactgcaag
    21541 gatggtcaat acagttacaa gcggagtcaa ctgaggaatg gttacgttgc gaatacgttg
    21601 ccacttgcta gctccgtcca ctgtcgctgc ttcgtagtag gttggatcaa ttcccatgat
    21661 cgtcgcatag tacatgacac tgctatatcc aaaacctttc caaataccta ggaaaagtag
    21721 gagatagggc cagatgccca ggtcagcgta gaaattgact tctttgagac caagactttc
    21781 caatagatga ttgaacaccc ctttatcaat atttaggaag gcatctgtaa agaaactgat
    21841 gataacccaa gacaagaagt aagggaacaa catagaagtt tggaaaatct tcaccattct
    21901 cttagaacgg agctcgctga ggataatggc aatccctaca gatacaacta aacctagaaa
    21961 gataaagcca agattgtaga ggacagtatt tcgtgtgata ataaaggcgt ctcttgaact
    22021 aaataagaat ctgaaattat cgagtccgac ccatttacta tttatgatac tatctatgaa
    22081 accattactg gtcatgtggt agtctttgaa ggcaaccacg ttcccaaata ctggaatgta
    22141 aaagaataga atcaaccaga gtgcccctgg caaaaccatc aagagaaaga tccagttgtc
    22201 tctcaatgtt tttgaaaact ttttcataat ttcctccctt tttattttga tatccatcta
    22261 aaaattcttt tttagacttt tgataacgat tacattatta gtatactcct atttgcaggt
    22321 taggttaaac tcctaattat agaaaaaatt ccacaaatta tgtagcagat ttaaaacttt
    22381 atcaccacta tcaaacaaat gtcctaaatc aattgtttat tttatctcta ttagcccagt
    22441 gatggcgtca ctctgttata agcatccaac aacggggtat actgaaaaat ctccagacta
    22501 gggaactcag cgatagttcc taatctggag atttttaata tgttattagg cgtttgcttt
    22561 caacttagca ataacctctt taagattatc aatcaactct gcttcagtat gctcagagcc
    22621 tttttcatct gccaagaaca aaactgcttt ttgaagttct tcttgagagt tttcaaggac
    22681 atccttatct gctgtttctt tgcccgctgt ttgtcctcca tccttagttg ctgactggct
    22741 ttccttaatg gactctaggg aagcaatggc atctttgact gtttgcaaga tatcacgtaa
    22801 accttgctct gtcaaactat catctgtaag agctttctta gcctctgcca aaaccagacg
    22861 tgctgaatct gtggtaggat tcgatacacc tgtcaatgat ctcaaaagat tttctaaggt
    22921 ttgagtctgc ttactaatac tagactaaaa tcaaaaagca ttacataaca gtgatatgaa
    22981 atcaactaaa gaagaaatcc aaaccatcaa aacactttta aaagactctc gtacagctaa
    23041 atatcataaa cgccttcaaa tcgttctata gtaaaatgaa acaagaacag gacaaatcga
    23101 tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt
    23161 tcaatccatt atatttcgtc tgatgggcaa atcttataaa gagattatag agcttttata
    23221 gtgatttgaa ataagatgtg aacaactcta tcaggaaagt caaattaatt tatagaaata
    23281 ttttagcagc caaggtgtac tgttatagat tcaatacact atacttggtg gtttagctct
    23341 cctgttttct cttttagctt taaccagcca taaatggtat tacgtgagat ttggaaaacg
    23401 tgtgatgctt ctgttatact acctgttcgc tcacaataag agagaacttt tttacgaaaa
    23461 tctattgaat attccataaa agattatacc acattgtgta ctatttttgg ttcattttac
    23521 tatatcactt tggactatat cggtctagtt atgtctaaac gattatagct ggatactaag
    23581 agaaatcaaa aaagcactaa gggagaacgt cccaaagtgc ttagtttcaa ggctttacag
    23641 cctatcttat ttaataaaat attacaacat tttgttgtag aattcaacga caagtgcttc
    23701 gttgatttct gggttgattt cgtcgcgttc tggcaagcga gtcaatgaac cttccaattt
    23761 ttcagcgtcg aatgatacga atgctggacg tccaagagta gcttctactg cttcaaggat
    23821 tgctggaact ttcaatgatt tttcacgaac tgagatcact tgacctggag ttacgcggta
    23881 tgatgggata tcaacgcgtt tcccgtcaac aaggatgtga ccgtggttta caaattgacg
    23941 agcttgacga cgagtagtcg cgagaccaag acggtaaaca acgttatcca aacgacgttc
    24001 caaaagaagc ataaagttga aacctaggat tccgcctttg atttttgtag cttgtacaaa
    24061 caagttacgg aattgttttt cacctacacc gtaagtgaaa cgaagttttt gtttttcagc
    24121 caattgcaaa ccgtattctg acaatttaga acggttgttt ggtccgtgtt gtcctggtac
    24181 gtagttacga cgtgccaatt ctttacctgt acctgtaagt gaaaggccaa ggcgacgagc
    24241 ttgtttccaa gatggtcctg tataacgtga catatgaatg tcctcctgat ataaataata
    24301 tttcggtgga aatagtcact tagaaagccc tgattcgtgc agatgccctt cgcctaaaca
    24361 gccaaggtta cttatcataa gacacctgtt gacgagcttc atgctttcct gctgatattt
    24421 cacacaaaat tcattctacc atgaatagct ggatttgtaa aggggtttta ggctttattt
    24481 tcactaccag agaggttgag aacgagagta aaggtacttc ctagaccgta ctggctgctg
    24541 actgtgattt ccccacccaa ttgatgggcc aattcacgcg caatcgcaag tcctaatcca
    24601 tgaccacctg tcttcatgtt acgcgaagtt tcgacacgat aaagacgttt gaaaatattt
    24661 tccaaatcct ctggggcaat accctgccct tcatcggtca cactgattga aagctggtcc
    24721 ttctccagct tagccaccac ttccagcttg gttcctggag cagaatattt aaaagcgtta
    24781 tcgaccagat tcaccaagat acgagaaagc ttagcataat ctccctcaat ccgggcagac
    24841 tctgggatta cctgcaagtg gacatctctt ctctcctgct caatcaaaaa ctgaaattca
    24901 ctcatgcact caattaagag cttgtccaga aaaatactgt ctttactggt agtttccacc
    24961 tgatttctag ctgtgtttag ggtcaaaaaa ttcaactcct caaccagttt attgagcctc
    25021 tccgtctggc gtccaatggt tgctagataa tgagcttgct ccgactcctt gataatccca
    25081 tccaaaatcc cttctaccgt cgcttgaatc gaagtgatag gggtcttaat atcatgcgac
    25141 aactgggcaa tcatcaagcc cttttctcgt tcgctttctt ccaaggaatc aaagcttacc
    25201 tgcaaatcat gggacatctc attaaaagtt tgccctaatt gctgaaattc tacaggacct
    25261 tgaacctcca aatttgaagg aaaatccttg gccgctaccc gcttggcatg ctccttgagt
    25321 ttgcccaacg acgtaaagac tggcaatagg agaaagagac taatcccagc accgacaagg
    25381 ctggcaacga tggtcatccc aagcaaaaag taaatctcgc ctttcgcaat cagcattttt
    25441 tgaacagccc aaaaaacaac caaaatggtt aagagggttg aaataatata tccaaccaaa
    25501 atataacttt ttagtttcat gtttgtcctc tcggtttctc tatcttatat cccaaccccc
    25561 aaactgtctt aatagtgggc gtttggtcac tactatattt tgccagctcc tgtcgaagag
    25621 catggatatg cacattcaag gtattggtgt catccacgta gtcttctttc cagatctttt
    25681 catagaggtc tgtcttggag aaaactcgct ctggattgct agctaaaatc cacagcaatt
    25741 caaatgattt aacagttaaa tccagcattt cttctcctat ttgaacttca tgactactat
    25801 gattcatttt tagattgcca agggaaatca gctctgtttc gcccccacga tgaaggcggc
    25861 gcaaaatatt gtggacacgc aaaactagct cacgtgggct aaaaggctta gcaataaaat
    25921 catctgctcc caagctcagg ccgtaaatct tgtcctgttc actggtctta gcagtaataa
    25981 ataggaaagg ctgctctggt gataagtatt gaacctcact gattaaatca taaccatcca
    26041 tccgaggcat catgacatct gtgataatca aatcaatcgg ttttttcttg aacagctcta
    26101 gcgcttccag tccatcatgg gctaccaaga cctgataacc tgcctgaatt aagtatctct
    26161 gatgaatatc tgtgatttct acctcgtcgt caacgagtaa aattgtcttt cccatctgtc
    26221 tctcctttga taaaaacagt gctatactgc tttaagtata acactatttt tattgtttta
    26281 cgatgatttt aatctgctat tgaaagaaag tcctgattgc tgattgagtt gttaaactaa
    26341 tcttagtcag cccactatcc atcatttatt tccttagctg attagttttc ttcttttttg
    26401 tttttcaaac ctagaccacc gagtaaacct gcaagcgcaa gcccaaggaa accaatactt
    26461 gccattgatg tttgagtctc accagtattt ggtagcatag ctttatcctc tgacatcatc
    26521 gtatcagaca tcttgttagc agaagcagcc atgttttcac ctgccatcgt gttggtagaa
    26581 cttgtcatgg tgtcagcagg catgctatct gtagtacctg tagcatgatt gtgattcatc
    26641 ggagtcacgc cagaaccaga gttagaaggt gataatgaac catttgctgt gtctgatgtt
    26701 tctttaacat ttat
//
LOCUS       DAVKXA010000029        26381 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKXA010000029 DAVKXA010000000
VERSION     DAVKXA010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.029"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..984
                     /gene="lytB"
                     /locus_tag="VW883_001274"
     CDS             <1..984
                     /gene="lytB"
                     /locus_tag="VW883_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0274411.1"
                     /translation="SDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGK
                     WLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITIS
                     GLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYS
                     ADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEH
                     YHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDATPYLSAKTFDDVDKGILGAT
                     KWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1045..2700)
                     /gene="pavA"
                     /locus_tag="VW883_001275"
     CDS             complement(1045..2700)
                     /gene="pavA"
                     /locus_tag="VW883_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0274412.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2805..3302
                     /gene="ybeY"
                     /locus_tag="VW883_001276"
     CDS             2805..3302
                     /gene="ybeY"
                     /locus_tag="VW883_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0274413.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3283..3678
                     /locus_tag="VW883_001277"
     CDS             3283..3678
                     /locus_tag="VW883_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0274414.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3695..4594
                     /gene="era"
                     /locus_tag="VW883_001278"
     CDS             3695..4594
                     /gene="era"
                     /locus_tag="VW883_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0274415.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4643..5467
                     /gene="mutM"
                     /locus_tag="VW883_001279"
     CDS             4643..5467
                     /gene="mutM"
                     /locus_tag="VW883_001279"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0274416.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5467..6072
                     /locus_tag="VW883_001280"
     CDS             5467..6072
                     /locus_tag="VW883_001280"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0274417.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6059..7258
                     /locus_tag="VW883_001281"
     CDS             6059..7258
                     /locus_tag="VW883_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0274418.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGIGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7258..7407
                     /gene="rpmG"
                     /locus_tag="VW883_001282"
     CDS             7258..7407
                     /gene="rpmG"
                     /locus_tag="VW883_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0274419.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7447..7680
                     /gene="secG"
                     /locus_tag="VW883_001283"
     CDS             7447..7680
                     /gene="secG"
                     /locus_tag="VW883_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0274420.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7782..10136
                     /gene="rnr"
                     /locus_tag="VW883_001284"
     CDS             7782..10136
                     /gene="rnr"
                     /locus_tag="VW883_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0274421.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10099..10566
                     /gene="smpB"
                     /locus_tag="VW883_001285"
     CDS             10099..10566
                     /gene="smpB"
                     /locus_tag="VW883_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0274422.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10582..11442
                     /gene="tehB"
                     /locus_tag="VW883_001286"
     CDS             10582..11442
                     /gene="tehB"
                     /locus_tag="VW883_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0274423.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11515..12468
                     /gene="coiA"
                     /locus_tag="VW883_001287"
     CDS             11515..12468
                     /gene="coiA"
                     /locus_tag="VW883_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0274424.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12487..14289
                     /gene="pepF"
                     /locus_tag="VW883_001288"
     CDS             12487..14289
                     /gene="pepF"
                     /locus_tag="VW883_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0274425.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14291..15004
                     /locus_tag="VW883_001289"
     CDS             14291..15004
                     /locus_tag="VW883_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0274426.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15071..16012
                     /gene="prsA"
                     /locus_tag="VW883_001290"
     CDS             15071..16012
                     /gene="prsA"
                     /locus_tag="VW883_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0274427.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16128..16469)
                     /locus_tag="VW883_001291"
                     /pseudo
     CDS             complement(16128..16469)
                     /locus_tag="VW883_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            16882..16977
                     /locus_tag="VW883_001292"
                     /pseudo
     CDS             16882..16977
                     /locus_tag="VW883_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17230..17850)
                     /locus_tag="VW883_001293"
     CDS             complement(17230..17850)
                     /locus_tag="VW883_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0274428.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(17850..18332)
                     /locus_tag="VW883_001294"
     CDS             complement(17850..18332)
                     /locus_tag="VW883_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0274429.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18332..19174)
                     /locus_tag="VW883_001295"
     CDS             complement(18332..19174)
                     /locus_tag="VW883_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0274430.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19269..20069)
                     /locus_tag="VW883_001296"
     CDS             complement(19269..20069)
                     /locus_tag="VW883_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0274431.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20213..21592
                     /gene="glmU"
                     /locus_tag="VW883_001297"
     CDS             20213..21592
                     /gene="glmU"
                     /locus_tag="VW883_001297"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0274432.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21602..22147
                     /locus_tag="VW883_001298"
     CDS             21602..22147
                     /locus_tag="VW883_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0274433.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            22159..22473
                     /locus_tag="VW883_001299"
     CDS             22159..22473
                     /locus_tag="VW883_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0274434.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22490..23182
                     /locus_tag="VW883_001300"
     CDS             22490..23182
                     /locus_tag="VW883_001300"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0274435.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            23259..23750
                     /gene="rocS"
                     /locus_tag="VW883_001301"
     CDS             23259..23750
                     /gene="rocS"
                     /locus_tag="VW883_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0274436.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23848..24438
                     /locus_tag="VW883_001302"
     CDS             23848..24438
                     /locus_tag="VW883_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0274437.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24447..26210
                     /locus_tag="VW883_001303"
     CDS             24447..26210
                     /locus_tag="VW883_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEV0274438.1"
                     /translation="MKPEKPKKLGLKQIYLDLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         8016 a         4800 c         5796 g         7769 t
ORIGIN      
        1 tctgatggca aaatggctga aaaagaatgg gtctacgatt ctcatagtca agcctggtac
       61 tacttcaaat ctggtggcta catggcgaaa aatgagacag tagatggtta tcagcttgga
      121 agcgatggta aatggcttgg aggaaaagct acaaatgaaa atgctgctta ctatcaagta
      181 gtgcctgtta cagccaatgt ttatgattca gatggtgaaa agctttccta tatatcgcaa
      241 ggtagtgtcg tatggctaga taaggataga aaaagtgatg acaagcgctt ggctattact
      301 atttctggtt tgtcaggcta tatgaaaaca gaagatttac aagcgctaga tgctagtaag
      361 gactttatcc cttattatga gagtgatggc caccgttttt atcactatgt ggctcagaat
      421 gctagtatcc cagtagcttc tcatctttct gatatggaag taggcaagaa atattattcg
      481 gcagatggcc tgcattttga tggttttaag cttgagaatc ccttcctttt caaagattta
      541 acagaggcta caaactacag tgctgaagaa ttggataagg tatttagttt gctaaacatt
      601 aacaatagcc ttttggagaa caagggcgct acttttaagg aagccgaaga acattaccat
      661 atcaatgccc tttatctcct tgcccatagt gccctagaaa gtaactgggg aagaagtaaa
      721 attgccaaag ataagaataa tttctttggc attacagcct atgatgcgac cccttacctt
      781 tctgctaaga catttgatga tgtggataag ggaattttag gtgcaaccaa gtggattaag
      841 gaaaattata tcgatagggg aagaactttc cttggaaaca aggcttctgg tatgaatgtg
      901 gaatatgctt cagaccctta ttggggcgaa aaaattgcta gtgtgatgat gaaaatcaat
      961 gagaagctag gtggcaaaga ttagtactat aagtgaatat gatttgagtg aatagtaagt
     1021 taaaaatcct gatttcaagt aaaatcagga ttttttcatg gatgcaattt ttttggagtc
     1081 tggtgtgacg cggagggtct tttgtcctgt gtaagtgaca aagccgggtt ttccaccagt
     1141 tggtttattg agttttttga cttcaatcat atctacctgc accagattcg acaggcgccc
     1201 ttgagagaag taggcagcta actctgctgc gtctgtcttg actgcatcag atgggtcaag
     1261 atttcctgag atgacaacat ggcttccagg aatgtcctta gcatggaacc aaagttcctc
     1321 cttgcgggcc attttaaagg tcaattcctc attttgaaga ttgtttcgtc cgacatagat
     1381 gatggttttg ccatcgcttg ctagatattg ttctagtttt ttgcgtttct ggattttctc
     1441 ccgttgtctt ctgcggataa aacctgtttg aatcaattct tcacggattt cagcgatttc
     1501 ttccagtcca gcttggttga ggacggtttc tacactttcc agatagagaa tagtggcttt
     1561 ggtttcttca atcaaatcag tcaagtattt gacagcttct ttgagtttct gataccgttt
     1621 aaaatagcgt tgggcattct ggttgggagt cagagcctta tcaagcgcaa tcatgatagg
     1681 ttggttggta tagtagttgt ctaggataac ctggtcttgg tcgttaggca cttggtggag
     1741 gaaggttgtc agcaattctc ctttttgacg aaattcttca gcgttgtctg tcgccagtaa
     1801 ctctttttcc tgttttttga gtttgtgtcg gtttttctga agttcatttt caacacgacg
     1861 aatcagttca ctggcctgct gtttgacgcg gtcgcgctca gccttatcct tatagtaggt
     1921 gtccaacaaa tcagaaagat ttgcaaaagg ctctcccacc tgatttgcaa aaggaactgg
     1981 actgaaggaa gtctcagtca agcatggctt ggtttcttga ttgaaaaaat ttcggaaagc
     2041 ggaaagtttt tcactaacca gtatcctttc caattcattt gccgtatcgc gtcccagacc
     2101 ttgaaagagg ctttgaagat tttttgctgt tagttcttgg gtttgtagga tttcaaagag
     2161 cttttcatcc ttgatagtaa aaggattgag agattttgta cttggcggag cgatataggt
     2221 cgatcctgga agtaaggtgc ggtagctatt ttgtgaaaaa ccgacgtgtt tgataacttc
     2281 gaggatttta tgactgcttt tatcgaccag tagaatatta ctgtgttttc ccataatttc
     2341 aataatcaag gtagcctgga tatggtctcc aatctcgttt ttattggaaa ctgtaatttc
     2401 cacaatacgg tcattttcca cttgctcaat cgactcaatc agggccccct gcaaatactt
     2461 tctcaaaacc atgataaagg tagaaggttg agctggattt tcaaaagtcg tttgggtcag
     2521 ctgaatgcgt ccaaaaactg gatgggcaga aaggagcagg cgatggcttt ggcgattgct
     2581 gcggatttgc aagaccaact cttgttcaaa aggctgattg attttctgga tgcgaccatt
     2641 cactaattcg cttcgcaatt cctcaactat gtggtgtaaa aaaaatccgt caaatgacat
     2701 cgttctctcc ttgtgattgt attccatagt attatatcaa aaaggtagaa taaaatcatg
     2761 gaaatgtggt ataataaagc caagtaaaga gaaacgagaa gcacatgtat attgaaatgg
     2821 tagatgaaac tggtcaagtt tcaaaagaaa tgttgcaaca aacccaagaa attttggaat
     2881 ttgcagccca aaaattagga aaagaagaca aggagatggc agtcactttt gtgaccaatg
     2941 agcgtagtca tgaacttaat ctggagtacc gtgacaccga ccgtccgaca gatgtcatca
     3001 gccttgagta taaaccagaa ttggaaattg cctttgacga agaggatttg cttgaaaatc
     3061 cagaattggc agagatgatg tctgagtttg atgcctatat tggggaattg ttcatctcta
     3121 tcgataaggc tcatgagcag gccgaagaat atggtcacag ctttgagcgt gagatgggct
     3181 tcttggcagt acacggcttt ttacatatta acggctatga tcactatact ccggaagaag
     3241 aagcggagat gttcggttta caagaagaaa ttttgacagc ctatggactc acaagacaat
     3301 aaacgaaaat ggaaaaatcg tgacttgata tccagtttag aatttgccat cacagggatt
     3361 tttactgcta tcaaggaaga acgaaatatg cgaaaacatg cagtgacggc tctagtggtc
     3421 atccttgcag gttttgtttt tcaggtgtca cgaatcgaat ggctctttct cctattgagt
     3481 attttcttgg tagtagcctt tgagattatc aactctgcta ttgaaaatgt ggtggatttg
     3541 gccagtcact atcacttttc catgctggct aaaaatgcca aggatatggc ggctggcgcg
     3601 gtattagtgg tttctctttt tgcagcctta acaggcgcat tgatttttct cccacgaatc
     3661 tgggatttat tattttaaac agtaagagga aattatgact tttaaatcag gctttgtagc
     3721 cattttagga cgtcccaatg ttgggaagtc aaccttttta aatcacgtta tggggcaaaa
     3781 gattgccatc atgagtgaca aggcgcagac aacgcgcaat aaaatcatgg gaatttacac
     3841 gactgataag gagcaaattg tctttatcga cacaccaggg attcacaaac ctaaaacagc
     3901 tctcggagat ttcatggttg agtctgccta cagtaccctt cgcgaagtgg acactgttct
     3961 tttcatggtg cctgctgatg aagcgcgtgg taagggggac gatatgatta tcgagcgtct
     4021 caaggctgcc aaggttcctg tgattttggt ggtgaataaa atcgataagg tccatccaga
     4081 ccagctcttg tctcagattg atgacttccg taatcaaatg gactttaagg aaattgttcc
     4141 aatctcagcc cttcagggaa ataacgtgtc tcgtctagtg gatattttga gtgaaaatct
     4201 ggatgaaggt ttccaatatt tcccgtctga tcaaatcaca gaccatccag aacgtttctt
     4261 ggtttcagaa atggttcgcg agaaagtctt gcatctaact cgtgaagaga ttccgcattc
     4321 tgtagcagta gttgttgact ctatgaaacg agacgaagag acagacaagg ttcacatccg
     4381 tgcaaccatc atggtcgagc gcgatagcca aaaagggatt atcatcggta aaggtggcgc
     4441 tatgcttaag aaaatcggta gcatggcccg tcgtgatatc gaactcatgc taggagacaa
     4501 ggtcttccta gaaacctggg tcaaggtcaa gaaaaactgg cgcgataaaa agctagattt
     4561 ggctgacttt ggctataatg aaagagaata ctaagtagag gtaggctcat gcctgcttct
     4621 tgtttttaca gaaggaggac ttatgcctga attacctgag gttgaaaccg tttgtcgtgg
     4681 cttagaaaaa ttgattatag gaaagaagat ttcgagtata gaaattcgct accccaagat
     4741 gattaagacg gatttggaag agtttcaaag ggaattgcct agtcagatta tcgagtcaat
     4801 gggacgtcgt ggaaaatatt tgctttttta tctgacagac aaggttttga tttcccattt
     4861 gcggatggag ggcaagtatt tttattatcc agaccaagtg cctgaacgca agcatgccca
     4921 tgttttcttc cggtttgaag atgggggcac gcttgtttat gaggatgtac gcaagtttgg
     4981 aaccatggaa ctcttggtgc ctgacctttt agacgcctac tttatttcta aaaaattagg
     5041 tcctgaacca agcgaacaag actttgattt acaggtcttt caagctgccc ttgccaagtc
     5101 caaaaagcct atcaaatccc atctcctaga ccagaccttg gtagctggac ttggcaatat
     5161 ctatgtggat gaggttctct ggcgagctca ggttcatcca gctagacctt cccagacttt
     5221 gacagcagaa gaagcgactg ccattcatga ccagaccatt gctgttttgg gccaggctgt
     5281 tgaaaaaggt ggctccacca ttcggactta taccaatgcc tttggggaag atggaagcat
     5341 gcaggacttt catcaggtct atgataagac tggtcaagaa tgtgtacgct gtggtaccat
     5401 cattgagaaa attcaactag gcggacgtgg aacccacttt tgtccaaact gtcaaaggag
     5461 ggactgatgg gaaaaatcat cggaatcact gggggaattg cctcaggtaa gtcaactgtg
     5521 acaaattttc taagacagca aggctttcaa gcagtggatg ccgacgcagt cgtccaccaa
     5581 ctacagaaac ctggtggtcg tctgtttgag gctctagtac agcactttgg gcaagaaatc
     5641 attcttgaaa acggagaact caatcgccct ctcctagcta gtctcatctt ttcaaatcct
     5701 gaagagcaaa aatggtctaa gcaaattcaa ggggagatta tccgtgagga actggctact
     5761 ttgagagaac agttggctca gacagaagag attttcttca tggatattcc cctacttttt
     5821 gagcaggact acagcgattg gtttgctgag acttggttgg tctatgtgga ccgagatgcc
     5881 caagtagaac gcttaatgaa aagggaccag ttgtccaaag atgaagctga gtctcgtctg
     5941 gcagcccagt ggcctttaga aaaaaagaaa gatttggcca gccaggttct tgataataat
     6001 ggcaatcaga accagcttct taatcaagtg catatccttc ttgagggagg taggcaagat
     6061 gacagagatt aactggaagg ataatctgcg tattgcctgg tttggtaatt ttctgacagg
     6121 agccagtatt tctttggttg taccttttat gcccatcttc gtggaaaatc taggtatagg
     6181 gagtcagcaa gtcgcttttt atgcaggctt agcaatttct gtctctgcta tttccgcggc
     6241 gctcttttct cctatttggg gtattcttgc tgacaaatac ggccgaaaac ccatgatgat
     6301 tcgggcaggt cttgctatga ctatcactat gggaggcttg gcctttgtcc caaatatcta
     6361 ttggttaatc tttcttcgtt tactaaacgg tgtatttgca ggttttgttc ctaatgcaac
     6421 ggcactgata gccagtcagg ttccaaagga gaaatcaggc tctgccttag gtactttgtc
     6481 tacaggcgta gttgcaggta ctctaactgg tccctttatt ggtggcttta tcgcagaatt
     6541 atttggcatt cgtacagttt tcttactggt tggtagtttt ctatttttag ctgctatttt
     6601 gactatttgc tttatcaagg aagattttca accagtagcc aaggaaaagg ctattccaac
     6661 aaaggaatta tttacctcgg ttaaatatcc ctatcttttg ctcaatctct ttttaaccag
     6721 ttttgtcatc caattttcag ctcaatcgat cggccctatt ttggctcttt atgtacgcga
     6781 cttagggcag acagagaatc ttctttttgt ctctggtttg attgtgtcca gtatgggctt
     6841 ttccagtatg atgagtgcag gagtcatggg caagctaggt gacaaggtgg gcaatcatcg
     6901 tctcttggtt gtcgcccagt tttattcagt catcatctat ctcctctgtg ccaatgcctc
     6961 tagccccctt caactaggac tctatcgttt cctctttggc ttgggaaccg gtgccttgat
     7021 tcccggggtt aatgccctac tcagcaaaat gactcccaaa gccggcattt cgagggtctt
     7081 tgccttcaat caggtattct tttatctggg aggtgttgtt ggtcccatgg caggttctgc
     7141 agtagcaggt caatttggct accatgctgt cttttatgcg acaagccttt gtgttgcctt
     7201 tagttgtctc tttaacctga ttcaatttcg aacattatta aaagtaaagg aaatctagtg
     7261 cgagtaaaaa ttaatctcaa atgctcctct tgtgacagta tcaattacct aaccagtaaa
     7321 aattcaaaaa cccatccaga caagattgag gttttaaagt attgtcccaa ggaaagaaaa
     7381 gtaaccctac atcttgaatc taagtagatt ttatggtaaa ataataggga ttttaaggag
     7441 tttgatatgt ataacctatt attaaccatt ttattagtat tatctgttgt gattgtgatt
     7501 gcaattttca tgcaaccaac caaaaaccaa tccagcaatg tatttgatgc cagttcaggt
     7561 gatttgtttg aacgcagtaa agctcgcggt tttgaagctg taatgcagcg tttgacaggg
     7621 attttagtct ttttctggct agccattgcc ttagcattga cggtattatc aagtagataa
     7681 gaaaataatg ggcaggacta ggtctttgcc tctttttatt tttaaaggat gtttgagaag
     7741 gttttacagt aaaagaaaat taaaaaatct agaaagaaaa tatgaaagat agaataaaag
     7801 aatatttaca agacaaggga aaggtgactg ttaatgattt ggctcaggct ttgggaaaag
     7861 acagttccaa ggattttcgt gagttgatta aaaccttgtc cttaatggaa agaaagcacc
     7921 agattcgctt tgaagaagat ggcagtctga ccttggaagc caagaaaaaa catgagatta
     7981 ccctcaaggg gatttttcat gcccataaaa atggttttgg ttttgtcagc ctagaagggg
     8041 aagaggacga cctttttgta gggaaaaatg atgtcaacta tgctattgat ggtgataccg
     8101 tcgaggtagt gattaagaaa gtcgctgacc gcaataaggg aacagcagca gaagccaaaa
     8161 ttattgatat cctagaacac agtttgacaa cagttgtcgg gcaaatcgtt ctggatcagg
     8221 aaaagcctaa gtatgctggc tatattcgtt caaaaaatca gaaaatcagt caaccgattt
     8281 atgttaagaa accagcccta aagttagaag gaacagaagt tctcaaggtc tttatcgata
     8341 aatacccaag caagaaacat gatttctttg tcgcgagtgt tctcgatgta gtgggacact
     8401 caacggatgt cggaattgat gttcttgagg tcttggaatc aatggacatt gtatccgagt
     8461 ttccagaagc tgttgttaag gaagcagaaa gtgtgcctga tgctccgtct caaaaggata
     8521 tggaaggtcg tctggatcta agagatgaaa ttacctttac cattgacggt gcggatgcca
     8581 aggacttgga cgatgcagtg catatcaagg ctctgaaaaa tggcaatctg gagcttgggg
     8641 ttcacatcgc agatgtttct tattatgtga ccgaggggtc tgcccttgac aaggaagccc
     8701 ttaaccgtgc gacttctgtt tacgtgacag accgagtggt gccaatgctt ccagaacgac
     8761 tatcaaatgg catctgctct ctcaatcccc aagttgaccg cctgacccag tctgctatta
     8821 tggagattga taaacatggt cgtgtggtca actataccat tacacaaaca gttatcaaga
     8881 ccagttttcg tatgacctat agcgatgtca atgatatcct agctggcgat gaagaaaaga
     8941 gaaaagaata tcataaaatt gtaccaagta tcgaactcat ggccaagctt catgaaactt
     9001 tagaaaacat gcgtgtgaaa cgtggagctc tcaattttga taccaatgaa gcgaagattt
     9061 tagtggataa acaaggtaag cctgttgata tcgttcttcg gcagcgtggc attgccgagc
     9121 ggatgattga gtcttttatg ttgatggcta atgaaacagt tgccgaacat ttcagcaagt
     9181 tggatttgcc ttttatctac cgaattcacg aggagcctaa ggctgaaaag gttcagaagt
     9241 ttattgatta tgcttcgagt tttggcttgc gcatttatgg gactgccagt gagattagcc
     9301 aggaggcact tcaagacatc atgcgtgctg ttgagggaga accttatgca gatgtattgt
     9361 ccatgatgct tcttcgctct atgcagcagg ctcgttattc ggagcacaat cacggccatt
     9421 atggattagc ggctgactat tatactcact ttactagtcc gattcgtcgt tatccagacc
     9481 ttcttgttca ccgtatgatt cgggattacg gccgttctaa ggaaatagca gagcattttg
     9541 aacaagtgat tccagagatt gcgacccagt cttccaaccg tgaacgtcgt gccatagaag
     9601 ctgagcgtga agttgaagcc atgaaaaagg ctgagtatat ggaagaatac gtgggtgaag
     9661 agtatgatgc agttgtatca agtattgtca aattcggtct ctttgtcgaa ttgccaaaca
     9721 cagttgaagg cttgattcac atcactaatc tacctgaatt ttatcatttc aatgagcgtg
     9781 atttgactct tcgtggagaa aaatcaggta tcactttccg agtgggtcag cagatccgta
     9841 tccgtgttga aagagcggat aaaatgactg gagagattga tttttcattc gtacctagtg
     9901 agtttgatgt gattgaaaaa ggcttgaaac agtctagtcg tagtggcaga ggacgtggtt
     9961 caaatcgtcg ttcggataag aaggaagaca agagaaaatc aggacgctca aatgataagc
    10021 gtaagcattc acaaaaagac aagaagaaaa aaggaaagaa acctttttac aaggaagtag
    10081 ctaagaaagg agccaagcat ggcaaagggc gagggaaagg tcgtcgcaca aaataaaaag
    10141 gcacgccacg actatacaat cgtagatacg ctagaggcag ggatggtcct gactggaact
    10201 gaaatcaaga gtgtacgagc tgctcgaatt aatctcaagg atggctttgc tcaagtgaaa
    10261 aatggagaag tttggctgag taatgttcat atcgcgcctt acgaagaggg caatatctgg
    10321 aaccaggaac cagaacgtcg tcgtaaactc ctgctccata aaaagcaaat tcaaaaattg
    10381 gaacaagaga ccaaagggac aggaatgacc ttagttcccc ttaaggtcta tataaaagat
    10441 ggctacgcta agcttctttt aggacttgcc aaagggaagc atgactatga caaacgggag
    10501 tctatcaaac gtcgtgagca aaatcgagat atcgcgcgtg tgatgaaagc tgttaatcag
    10561 cgataaaaag aggaattgaa aatggaaaaa ttagttgcct ataaacgcat gcctttgtgg
    10621 aataaacaaa caatgcctga agctgttcag caaaagcaca atacaaaagt tgggacttgg
    10681 gggaaaatta ctgtcttgaa gggagctctc aagtttattg aattgacaga agaaggggaa
    10741 gttctagctg aacacctctt tgaagcaggg gcagacaatc caatggccca acctcaagcc
    10801 tggcaccgag tggaagctgc cacagatgat gtggaatggt acttggaatt ttattgtaaa
    10861 cctgaggatt attttgctaa aaaatacaat accaatcctg ttcattcaga ggtcctagag
    10921 gccatgcaga cagtgaaaca agggaaagct ttggatttgg gttgtggtca ggggcgtaat
    10981 tctctttttc tagcccagca agattttgat gtgacggctg tagatcaaaa tggactagct
    11041 cttgaaatct tgcaaagcat tgtggagcag gaagatttgg acatgcctgt tggcctttac
    11101 gatatcaatt cagctagcat tgaacaagaa tatgatttta tcgtttcaac agttgttctc
    11161 atgtttctac aagcggaccg cattccagct attattcaaa atatgcagga gaaaaccagt
    11221 gttggtggtt acaaccttat cgtttgtgcc atggacacgg aggattatcc ttgctcggtt
    11281 aacttcccat tcacctttaa agaaggagaa ctggcagact attacaagga ttgggaattg
    11341 gttaagtaca atgaaaatcc aggccatttg caccgtcgcg atgagaatgg caatcgtatt
    11401 caactacgct ttgcgacctt actagctaag aaaatcaagt aaacacacat gaagattagg
    11461 aattttcctg atcttttttc ttttttacga atgatataga aaaggaggga attcatgttt
    11521 gttgcgagag atgctagggg agaattggta aatgtgttag aggataaact tgagaagcaa
    11581 gcatacacct gcccagcttg tggaggccag ctccatttgc gtcaaggacc aagtgtacgg
    11641 acgcattttg cccataaatc cttaaaagac tgtgattttt tctttgaaaa tgaaagtcca
    11701 gaacacctgg ccaataagga atccctctat cactggttga aaaaagagac aaaggttcaa
    11761 ttagagtacc cgctttcaga acttaaacag attgcggatg tatttgtaaa tggcaatcta
    11821 gctctagaag ttcagtgtag tcccttgcct cagaaagtcc ttaaagagcg aagtgagggc
    11881 tatcgtagtc agggttacca agtactgtgg ttgctgggtc aaaaactgtg gctcaaggag
    11941 cgtttgactc gtctacagca aggttttctg tatttcagtc aaaacatggg cttttatgtt
    12001 tgggaattag acaaggaaaa acaagtttta agactcaaat acctgattta ccaggatctc
    12061 cgcggtaaac tccattatca aatcaaggaa ttttcctatg gtcaaggtag tttattggaa
    12121 atattgcgtc ttccctataa gagacaaaaa atatctcatt ttacagtttc tgaggacaag
    12181 gacatctgtc gctatatccg gcaacaactt tattatcaaa atctcttttg gatgaaagaa
    12241 caagcagaag cctatcaaaa gggagaaaat atcctgactt atggactgaa agaatggtat
    12301 ccacaaattc gaccaatagt gggcaaattt ttccagattg aacaagactt gactagctat
    12361 tatcagcact tttataccta ttaccaaaaa aatcctcaaa atgattggca aaagctttat
    12421 ccaccagcct tttatcagca atatttcttg aaaaatatgg tagaatagaa aggatggagg
    12481 aatctaatgg tattacaaag aaatgaaata aatgaaaaag atacatggga tctatcaacg
    12541 atctacccaa ctgaccaggc ttgggaagaa gccttaaaag atttaacaga acaattggag
    12601 acagtagccc agtatgaagg ccatctcttg gatagtgcgg ataacctact agaaatcact
    12661 gaattttctc ttgaaatgga acgccagata gagaagcttt acgtttatgc tcatatgaag
    12721 aatgaccagg atacacgtga agctaagtat caagagtact atgccaaggc catgacactc
    12781 tacagccagt tagaccaagc cttttcattc tatgagcctg aatttatgga gattagcgaa
    12841 aagcagtatg ctgacttttt agaagctcaa ccaaagctgc aggtttatca acactatttt
    12901 gacaagctct tgcaaggcaa ggatcacgtt ctttcacaac gtgaagaaga attattggct
    12961 ggagctggag aaatctttgg ttcagcaagt gaaaccttcg ctatcttgga caatgcggat
    13021 attgtgttcc cttatgtcct agacgatgat ggtaaagaag ttcagctatc tcatgggact
    13081 tacacacgtt tgatggagtc taaaaaacgt gaggttcgcc gtggtgccta tcaagctctt
    13141 tatgcgactt acgaacaatt ccaacacacc tatgccaaaa ccttgcaaac caatgttaag
    13201 gtgcaaaatt accgtgctaa agttcgtaac tacaagagtg ctcgtcatgc agccctcgca
    13261 gcgaattttg ttccagaaag tgtttatgac aatttagtag cagcagttcg caagcatttg
    13321 ccactcttac atcgctatct tgagcttcgt tcaaaaatct tggggatttc agatctcaag
    13381 atgtacgatg tctacacacc gctttcatct gttgaataca gttttaccta ccaagaagcc
    13441 ttgaaaaaag cagaagatgc tttggcagtc ttgggtgagg attacttgag ccgtgttaaa
    13501 cgtgccttca gcgagcgttg gattgatgtt tacgaaaatc aaggcaagcg ttcaggtgcc
    13561 tactctggtg gttcttacga taccaatgcc tttatgcttc tcaactggca ggacaatctg
    13621 gacaatctct ttactcttgt tcatgaaaca ggtcacagta tgcattcaag ctatactcgt
    13681 gaaactcagc cttatgttta cggagattac tctatctttt tggctgagat tgcctcaact
    13741 accaatgaaa atatcttgac ggagaaatta ttggaagaag tggaagacga cgcaacacgc
    13801 tttgctattc tcaataactt cctagatggt ttccgtggaa cagttttccg ccaaactcaa
    13861 tttgctgagt ttgaacacgc cattcaccaa gcagatcaaa atggggaggt cttgacaagc
    13921 gatttcctaa ataaactcta cgcagacttg aaccaagagt attatggttt gagtaaggaa
    13981 gacaatcctg aaatccaata cgagtgggct cgcattccac acttctacta taactactat
    14041 gtatatcaat attcaactgg ctttgcggcc gcctcagcct tggctgaaaa aattgtccat
    14101 ggtagtcaag aagaccgtga ccgctatatc gactacctca aggcaggtaa gtcggactat
    14161 ccacttaatg tcatgagaaa agctggtgtt gatatggaga aggaagacta cctcaacgat
    14221 gcctttgcag tctttgaacg ccgtttaaat gagtttgaag cccttgttga aaaattagga
    14281 ttggcataaa atggttgaat cgtatagtaa gaatgctaac cataacatgc gtcgtcctgt
    14341 cgtcaaagaa gaaattgtag acttgatgcg tcagcgtcaa aagcaggtca caggtttctt
    14401 gaaagaattg gaagactttg cccgcaagga aaatattcct attattcccc atgaaacggt
    14461 tgcttatttc cgttttctta tggaaaccat gcagcctaaa aatattctgg aaattgggac
    14521 ggctatcggt ttttcagctc tcttgatggc tgaacatgcg ccaaatgcta agattacaac
    14581 tattgatcgt aatccagaaa tgattggttt tgccaaggaa aattttgccc agtttgacag
    14641 tcgcaagcaa atcactctcc tagagggaga tgcggtggat gtcttatcta cactgacaga
    14701 gtcttatgat ttcgtattta tggattctgc caagtctaaa tacatcgtct ttctgccaga
    14761 aatcctcaaa catttggaag ttggtggtgt ggttgtcttg gatgatattt ttcaaggtgg
    14821 tgatgttgcc aaggatatta tggaagtccg tcgtggtcag cgaaccattt atcgaggcct
    14881 tcaaaaatta tttgatgcaa ccttagacaa tccagaactc accgcaacat tagtgccttt
    14941 aggagatggt attctcatgc ttcgtaaaaa tgtagcagat gttcaactgt ctgaaagcga
    15001 atgattttca gaaaaattta agaaaaaata gtaaaataga tagagtaaca cttatctcaa
    15061 aggagtagac atgaagaaaa aattattggc aggtgccatc acactattat cagtagcaac
    15121 tttagcagct tgttcgaaag ggtcagaagg ggcagacctt atcagcatga aaggggatgt
    15181 catcacagaa catcaatttt atgagcaagt gaaaaacaac ccttcagccc aacaagtctt
    15241 gttaaatatg accatccaaa aagtttttga aaaacaatat ggctcagagc ttgatgataa
    15301 agaggttgat gatactattg ccgaagaaaa aaaacaatat ggcgaaaact accaacgtgt
    15361 cttgtcacaa gcaggtatga ctcttgaaac acgtaaagct caaattcgta caagtaaatt
    15421 agttgagttg gcagttaaga aggtagcaga agctgaattg acagatgaag cctataagaa
    15481 agcctttgat gagtacactc cagatgtaac ggctcaaatc atccgtctta ataatgaaga
    15541 taaggccaaa gaagttctcg aaaaagccaa ggcagaaggt gctgattttg ctcaattagc
    15601 caaagataat tcaactgatg aaaaaacaaa agaaaatggt ggagaaatta cctttgattc
    15661 tgcttcaaca gaagtacctg agcaagtcaa aaaagccgct ttcgctttag atgtggatgg
    15721 tgtttctgat gtgattacag caactggcac acaagcctac agtagccaat attacattgt
    15781 aaaactcact aagaaaacag aaaaatcatc taatattgat gactacaaag aaaaattaaa
    15841 aactgttatc ttgactcaaa aacaaaatga ttcaacattt gttcaaagca ttatcggaaa
    15901 agaattgcaa gcagccaata tcaaggttaa ggaccaagcc ttccaaaata tctttaccca
    15961 atatatcggt ggtggagatt caagctcaag cagtagtaca tcaaacgaat agtccaaatc
    16021 aatgagtcag ggaaaaaact cgacttcagg aaaaaatgaa gcaaacattc ccacaataaa
    16081 acgcatagta caaggtttgt actgacccca aaagttagac aattaattta tctgaaggat
    16141 ttagttctgt attgcacagg gctaagtcct tttagtttta ccttaattct cttattgttg
    16201 taataatcaa tatagtctat aatggcttgt tccaattgat taagtgattt aaatgttttc
    16261 tcatagccat aaaacatttc ggattttaaa atgccaaaga aagattccat cctaccgttg
    16321 tcttggctgt ttcctttgcg tgacatagat gcttgaattc ccttactctc taggaagcga
    16381 tgataagaat cgtgttgata ttgccagcct tggtcactat ggagaatcgt attctcgtag
    16441 tgcttctctt tgaatgcctg ttccaacatt aacgatcaat caatttaatc atgtacctaa
    16501 tattagaatt gtttatccca aatttatttg aaagcttctc taagctatat ccttgttttc
    16561 taagttcata gatctgaact ttatcatcat aagttaattt cataataaaa acaccccaaa
    16621 agttagattt tttctgtcta acttttgggg tgtagttcat gtacacctga tatgatgcgt
    16681 tttataattt taaagacttt ttgaccagcc tcattttttt aacttgatac tcagtgaaaa
    16741 gcaaagatta aactaggaag ctagctgtag gctgctcaaa gaacagcttt gaggttgcag
    16801 ataaaacttg tgaggtaacc aacatatata atgtgaagct gacgtggttt gaatagattt
    16861 tagaagggta tgagtctgga agttttaatg gataatgcaa gattccatag aatgggtaag
    16921 ctagagttct tatgtgaaga gtttgggcat aaacttttac cttttcctcc ctactcatct
    16981 tagtatagaa aagtgaatct aaaatagtac ataactgctt ctaaaacatt cttataaatt
    17041 gatttaaatt ctcaaatcat attattcagt tcttatttca ttttgctcta caatcctgtt
    17101 gagaagacac gtgttcatat caaaaaggta ttggcaagtt gcaatacctt tttacaaggt
    17161 tcttttgtct tatttttgtt tcaactgact atatctccta tggttctagt tcagaaggct
    17221 aggctataat tatgattgat aagaagtatc attccaagta ttgagagtga atgtttcaaa
    17281 atcatgggtt tctataatgg tcaggctggc atttgctaga ccgccatctt tacgaagaag
    17341 tggttcttta tagcctagga gagtacgaag actggcagta agattggcgc cgtgtccgac
    17401 aattagaata cgctcagctg gactatcttt taatgatttg ataaattgga tggtccgctg
    17461 agttgtacta tagagggatt cggctccgaa cattcgagtg tcaaattgag caagatttga
    17521 acgaaaagcc tggatttgtt gcgggtaaat agcttccagg gttgcaattt tcaaaccttc
    17581 taacttccca agttgccatt cacggagatt aggaacgatt tctaaagaac agggggtatg
    17641 gagttgactt tggataatct cagcagattt gaccgctcga ggtaaatcac ttgaataaat
    17701 ctgatcaaaa ggaatttcct tgagatactg gccaagtcgt tttagggttt caatggatcc
    17761 aggaagaaga ggagaatcac cgctagcacc ttgaaaacga ccttcttggt tccagagggt
    17821 acgaccgtgg cggacaaagt agagtttcat tacttgatgt cctccaaaat atctacaaag
    17881 tctgccttta caaagctagc caagtcttgt ggcgcgacga taatgctgtg tccgacttcg
    17941 cctgcagaga caatcattcg atccaaatct agagcaattt tatcgataaa aatgggataa
    18001 ttgtgtttct gacgaattcc gacaggatta ttggctccat gaatgtaacc agttgttttt
    18061 tctaagtcct tttgtggaat catgctcact tttttattgc cagaaatttt agctagtttc
    18121 ttttcagaca agtgctgagt gatagggaca attccgataa tcggtccggt cttgtctccc
    18181 aaaagcgcca aggttttgaa aatctgatct cgttcataac cttgaggaag ctctccttct
    18241 agggcattga tttgaatccc ctgatgaggg atagctgctt tagataggat ttgttccacc
    18301 aatgtttttt tgattttaac tttttttgcc attatttata tttatcctcc aattgactca
    18361 tccaaatacc aagccagatt cccagcgcaa agaagaaggc gatgatgaca taaccgacaa
    18421 gtgaaagtcc tgtgtattgg atactttcag cgtttcctgc atttggaatt aagatcaaaa
    18481 gggtacttga taggacgata ccgatgatga aatgatagac gcgtgagtgg tagttgttta
    18541 aggcataatc catcaatttt gaaaaaacga tgagagttgc acctgcacca attccaatcg
    18601 gaaagaaggt tcccaagaaa tcaaaagttt taaaaccagt caacatagga gcatagagtc
    18661 ccaaaatcaa aagtaaattt gatgggctga ggccaggaac caagacgcca agggccaata
    18721 gtgcgcctgc taggacgaag ttaagaaagc tggcgcttaa ggttccaacg acaaaattta
    18781 aggcatagag tcctaatcca gaaatgataa aggttgtcca taaccaagct aaatcaatct
    18841 tgtctcggtc agattctcga gttgattctt tgaggaggct aggaactgta ccgataatag
    18901 ctcccgcaaa gctccataat acaaaaacct gataattttc aagcaggtat tcaatcgggt
    18961 aggaaaataa gccgattccc agaagcatac cgatggcaac tggaataaag tacaaaacat
    19021 tttctttaaa gtctttaaag ggatgggcca gaaagccaat cattcgttca tagattccta
    19081 agattgctgc tagaacccct ccagaaattc ccggtaggat aaatccaaga gcaattacaa
    19141 tccctttaat aacgcgtgct aaccatgaga gcatatattt cctccaacta tttctatttc
    19201 aaaaaatcct tactatattg tatcacaatc agacacaaaa agaaaaagca aatgataaac
    19261 aaatgctttt aaggttttaa aaaaagtttt cgaaaggttt cttctttatt ttttaaggga
    19321 gagataacgt tgatatctaa atcgtggtca aagccggcaa tttttccttt agatgtgtat
    19381 tggtgaatat cataatctaa atcagtttta ggactgctct ccaaaaatcc tgagtctgag
    19441 ccgtaggacg gaatccaaac agaggtaaac ttgcctgtat caatactgtg ttcttccatg
    19501 aagtagacac caacgtagat gccgatgttt ttagcaccta gtgatgctag ttttgctcga
    19561 aagttttcga caccttcgtt catattagac atggttttgt cttccacgtc aagccaatag
    19621 taactagggc tgtaaggaga ggcagcattg tagaaaactt cggcagcctt ttccatttct
    19681 tggacacttt ttccagctac ataagcgtag acagcaactg ggacattccg cttttgaagt
    19741 tcagtgatat gactcttata ggccttgtct attccattga taaatgaagc atcattttct
    19801 tttgttgttt gagcaccact gtgaacacga acaatagcac ctgaaatatt ttgtgagagg
    19861 gcatcgtagt tgatttcctc aggacgctgc cagccagaga ggtcaataat cggtttgtct
    19921 aagtgtttca aagcctgtgc ttcaatctgt gctatattgg attttgtttt aaacgattgg
    19981 ctgtcattaa gtgggcgatt gatgattaaa atgaacatca taatcccaaa aaaactaaat
    20041 aaaataagtg gatgaatttg ttttctcata tcttataatt ctaccctaaa aatcaaaaaa
    20101 aatcaaaaaa atgggttaag gaagagactt tagagcattt tttcattcaa gagtgcggaa
    20161 tgatttgaaa tatggtataa taaaagggaa tttctacaga aaagagaaga ttatgtcaaa
    20221 ttttgccatt attttagcag cgggtaaagg gactcgcatg aaatctgatt tgccaaaagt
    20281 tttgcacaag gttgcgggta tttctatgtt ggaacatgtt ttccgtagtg tgggagctat
    20341 ccaacctgaa aagacagtaa cagttgtagg acacaaggca gaattggttg aggaggtctt
    20401 ggctgaacag acagaatttg tgactcaatc tgaacagttg ggaactggtc atgcagttat
    20461 gatgacagag cctatcttag aaggtttgtc aggacacacc ttggtcattg caggagatac
    20521 tcctttaatc actggtgaaa gcttgaaaaa cttgattgat ttccatatca atcataaaaa
    20581 tgtggccact atcttgactg ctgaaacgga taatcctttt ggctatggac gaattgttcg
    20641 taatgacaat gctgaggttc ttcgtattgt tgagcagaag gatgctacag attttgaaaa
    20701 gcaaatcaag gaaatcaaca ctggaacata cgtctttgac aacgagcgtt tgtttgaggc
    20761 tttgaaaaat atcaatacca ataacgctca aggcgaatac tatattacag acgtcattgg
    20821 tattttccgt gaaactggtg aaaaagttgg cgcttatact ttgaaagatt ttgatgaaag
    20881 tcttggggta aatgaccgtg tggcgcttgc gacagctgag tcagttatgc gtcgtcgcat
    20941 caatcataaa cacatggtca acggtgttag ctttgtcaat ccagaagcaa cttatatcga
    21001 tattgatgtt gagattgctc cggaagttca aatcgaagcc aatgttatct tgaaagggca
    21061 aacgaaaatt ggtgctgaga ctgttttgac aaacggtact tatgtagtgg acagcactat
    21121 cggagcagga gcggtcatta ccaattctat gattgaggaa agtagtgttg cagacggtgt
    21181 gacagtcggt ccttatgctc acattcgtcc aaattcaagt ctgggtgccc aagttcatat
    21241 tggtaacttt gttgaggtga aaggatcttc aatcggtgag aataccaagg ctggtcattt
    21301 gacttatatc ggaaactgtg aagtgggaag caacgttaat ttcggtgctg gaactattac
    21361 agtcaactat gacggcaaaa acaaatacaa gacagtcatt ggagacaatg tctttgttgg
    21421 ttcaaattca accattattg caccagtaga acttggtgac aattccctcg ttggtgctgg
    21481 ttcaactatt actaaagacg tgccagcaga tgctattgct attggtcgcg gtcgtcagat
    21541 caataaagac gaatatgcaa cacgtcttcc tcatcatcct aagaaccagt aggagcctat
    21601 catggagttt gaagaaaaaa cgcttagccg aaaagaaatc tatcaaggac caatatttaa
    21661 actggtccaa gatcaggttg aattaccaga aggcaaggga actgcccgac gggatttgat
    21721 tttccacaat ggggctgtct gtgttttagc agtaacggat gaacaaaaac ttatcttggt
    21781 caagcagtac cgcaaagcta tcgaggctgt ctcttacgaa attccagccg gaaaattgga
    21841 agtaggagaa aacacagccc ctgtggcagc tgcccttcgt gaattagagg aagaaacagc
    21901 ctatacaggg aaattagaac tcttgtacga tttttattca gctattggct tttgtaatga
    21961 gaagttaaaa ctatatttag caagcgattt gacaaaagtg gaaaatccgc gtccgcagga
    22021 tgaggatgaa accttggaag tccttgaagt gagcttagaa gaagcgaaag aattaatcca
    22081 atcaggtcat atctgtgatg ccaagacaat tatggctgtt cagtattggg agttgcagaa
    22141 aaaatagagg aggtcagtat gggtaaatct ttattaacgg atgaaatgat tgaaagagct
    22201 aatagaggcg aaaaaatttc aggtcctcct ttgctagatg ataatgagga aactaagatt
    22261 ttaccaacct cttcttcccg ttttggttat gccaatccta aggatcatgg ttttagccag
    22321 gaaaccttga agattcaggt cgaaccatct attcataaaa gccgtcgtat tgaaaatacc
    22381 aagagaaatg tcttcaattc taagttgaat aaaatcttat ttgcggtcat ctttctcttg
    22441 attttgcttg ttttagcaat gaaacttttg taatagaaaa ggaattgaaa tgaaaatagg
    22501 aattattgct gctatgccag aagaactggc ttatctggtc cagcatttag ataataccca
    22561 ggagcaagtt gttttgggga atacctatca tacaggaacc attgcttctc atgaagtcgt
    22621 tcttgtagaa agtggaattg gtaaggtcat gtctgctatg agtgtggcga ttttggctga
    22681 tcatttccag gtggatgccc ttattaatac gggttcagct ggggcagtag cagaaggtat
    22741 cgctgttggg gatgtcgtga ttgctgacaa attagcctat catgacgtgg atgtcacagc
    22801 ttttggctat gcttatggac aaatggcgca acaaccgctt tatttcgaat cagacaaaac
    22861 ctttgttgct caaatccaag agagtttatc tcaattggac caaaactggc atcttggttt
    22921 gattgctaca ggagatagtt ttgttgcagg aaatgacaag atagaagcga ttaagtccca
    22981 tttcccagaa gttttagccg tggagatgga gggggcagct attgctcaag cagcgcatgc
    23041 cctcaatctc ccagtcttag tcatcagagc tatgagtgac aatgccaacc atgaagcaaa
    23101 catctttttt gatgagttta ttatcgaagc tggacgtcgc tctgcccaag tcttgttgac
    23161 ctttttgaag gctttagatt aagcggaaat ttgacagttt ttctagctta tgataagatt
    23221 taagtaaaga aaagctagaa aacgtttcag aggatattat gagtattgaa atgaccgtca
    23281 gtgagattgc agaggtctta ggattatctc gccaagcaat caataaccgt gtcaaagaat
    23341 taccagaaga agacacagat aaaaatgaca aaggggtaac agttgttacc agaagtggct
    23401 tgattaagct agaagaaatc tataaaaaaa cgatttttga agatgagcct gtcagtgaag
    23461 atgtcaaaca acgtgaactg atggagattc tagtggatga gaagaatgca gaaattcttc
    23521 gtctttatga acaattaaaa gccaaggatc gtcagttatc agaaaaagac gagcagatgc
    23581 gtatcaaaga ccgtcagatt gctgaaaaag acaaacaatt agatcagcaa caacaattga
    23641 cccttcaagc catgaaggat caagaaaatc ttaagctaga gctggaccaa gcaaaagaag
    23701 aagtccaatc cactaaaaaa ggcttttttg ctcgtttatt tggaggataa tcaaggagct
    23761 gtttaggtta aatgctaacc tgatggcttc ttttgtttgt gaatagtata gttgattaga
    23821 acagagacag tagaggagag gtacagaatg gaacgattag aagattacat tgcttttgac
    23881 ttagaattta atcagcacga aggacaaaca cacttgattc aagtatcggc agtgcgtttt
    23941 agagatggtc gggaaatcga tgcctatgat tcctatgttc ataccagcgt ccctctaaaa
    24001 agctttatca atggtttgac cgggattaca gctgagacct taaaagatgc tcctccagtt
    24061 gagaaagtct tagaagaatt ccaagagttt gtgggttctt tgctgatgat aggctacaat
    24121 gctgctaaaa gtgatttacc tattttagca gagcatggtt tagactatag ccaacagtac
    24181 aaggtggatt tgtatgatga agcttttgaa cgtcggagtt cagatttaca tggtattgcc
    24241 aatctcaaat tgcaaactgt tgcctcattt cttggatttc aaggtcagtc tcataatagt
    24301 ttagaggatg ctcggatgac ggcgcgtgtt tacgaatcct tcttagagtc ggatcaagct
    24361 agggaattgt tagagacaga aagtagctta tcaaacaatc cttttggtgg cttggacttg
    24421 tctcaattat ttgactagga gtgcctatga aacctgaaaa acctaaaaaa ttgggtctta
    24481 aacagattta cctcgatctt gataaaatcc tctttctatt tttcttgatt tttatgatag
    24541 tggagtattt gtgggtacca ttcaattcat ggttggctag cttcttatta gatcagacag
    24601 gttatctttt tatttcctat aacaatgtct tagccatcct tactcattct ccattgatta
    24661 gtctagcttt tttagccttg attgtaatta accttctggt tgcttatttt caaataggac
    24721 tcctctttat tggtgctcgt catctcctct ataatgaaaa gcgaaggcta attgagtata
    24781 tccgcaaggt tttccatgaa agttttggat ttatgaaaaa gctaacttgc gctaaagcct
    24841 tgtttatctt tttctatata gctatgctgt ttccttttat acggaaaatg ctgaagattt
    24901 attatcttaa taaaatcgtc attccagagt ttatccaagc ttatttagaa gatagatatt
    24961 ggatgtggtg gctgagcatc ctacttctat ctcttatctt tctctatgtc tctgtcagat
    25021 tgatgtttgc ccttccgaag attgtatatg atcagctgac tgttcgagaa gcagtgatgt
    25081 ttagcttgga gaaaaccaag aagagagtta ctttttatgc ttggaattta ttttacatct
    25141 tgctcaaagc acatttatta ttttatcttc ctttgatccc tttattattg gctcaaactt
    25201 tggtagatga tatcactcag agagagtctc tgattcttgg tattttgaat tttgtcgtga
    25261 ttaaaaatct ctattatatg gctctgactt attttttggt taaatttgtt tcatttttga
    25321 caggaaagga gctggatatg cttcctagga gagaaaaaga tcacatcgtg cgatggggtg
    25381 tcatgacttg tgccagtctt ttctttgcct tagaaggtta tatttatctg gaggctccca
    25441 tggttcatct acctcaactt atttctcacc gaggggtttc caatgcaaat gggattcaaa
    25501 atacagtaga gtccttggaa actacagcac aactcaaacc agacttggtg gagacggacg
    25561 tgcaggaaac aaaagatggg cagtttgtca tgatgcatga tgctaacttg aaaaatctag
    25621 caggtatcaa taaaagtcct caagacttaa acttggagga gcttaaaggg attgatattt
    25681 ttgaaaatgg ctaccagact aaaatttcaa gctttgaaga ttatctcagt cgagccaacg
    25741 aacttggtca aaaattacta attgaaatta aaaccagtaa aaaagatagt ccagacatga
    25801 tgaaccgctt tttagcccgt tatgctgcaa agctcaagat ttatggacat caaatccagt
    25861 ctttagacta ccatgttgtc gaaaaagtaa gacagtatga tgccgaactg ccagtttatt
    25921 tcatcatgcc ctacaattct gtctttccta aaacaagagc gacaggatat actatggagt
    25981 actcaacctt ggatgaatat tttgtaagca aactatggac aacggatcag aaactttatg
    26041 tctggactgt caatgattca gaagctatca gcaaatctct tcacttagga gtagatggag
    26101 tgattacaga tgatttggaa aaagttcagc gggaaataga agtagcccaa gaagatccag
    26161 aatatacgga tttgctcttg aaaaaagcat tggaattctt tgaattttag taataaaaaa
    26221 gaggaacggt tgttcctccc atgataggta agtattcttg tgaatgcttg cttttttgtg
    26281 gttgcaatcc gtttacgaga attgtttgta ttgttcttgt ttcaatttac tttatagtgc
    26341 tttgaagttg gaatgctaca ctataactta taaaatatag t
//
LOCUS       DAVKXA010000030        25793 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKXA010000030 DAVKXA010000000
VERSION     DAVKXA010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.030"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(105..2363)
                     /locus_tag="VW883_001304"
     CDS             complement(105..2363)
                     /locus_tag="VW883_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0274439.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDTKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2592..2822)
                     /locus_tag="VW883_001305"
     CDS             complement(2592..2822)
                     /locus_tag="VW883_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0274440.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3012..3695
                     /locus_tag="VW883_001306"
     CDS             3012..3695
                     /locus_tag="VW883_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0274441.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3695..4429
                     /locus_tag="VW883_001307"
     CDS             3695..4429
                     /locus_tag="VW883_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0274442.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4583..5440
                     /locus_tag="VW883_001308"
     CDS             4583..5440
                     /locus_tag="VW883_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0274443.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAVGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLTIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5582..6454
                     /locus_tag="VW883_001309"
     CDS             5582..6454
                     /locus_tag="VW883_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0274444.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6736..7419
                     /gene="rpiA"
                     /locus_tag="VW883_001310"
     CDS             6736..7419
                     /gene="rpiA"
                     /locus_tag="VW883_001310"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0274445.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7433..8644
                     /locus_tag="VW883_001311"
     CDS             7433..8644
                     /locus_tag="VW883_001311"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0274446.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8646..9188
                     /locus_tag="VW883_001312"
     CDS             8646..9188
                     /locus_tag="VW883_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0274447.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKFESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9204..10013
                     /locus_tag="VW883_001313"
     CDS             9204..10013
                     /locus_tag="VW883_001313"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0274448.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10510..11532
                     /locus_tag="VW883_001314"
     CDS             10510..11532
                     /locus_tag="VW883_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV0274449.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLPEASEVLENKREESKVEI
                     TEPAQDSPILAPVEETKEEAVTEKPTNTRSLTAEDLVKISKGELHLENDLIDESFYGE
                     KALDLEGDDDQDGIKNKDGKDYLGYNSHPLLADSDGDGLADGEDDNKKEWYVTDRDSL
                     LFMELAYRDDDYIEKILYHKNLFPSLYLDRQEHKLMHNELAPFWKMKKAYYTDSGLDA
                     FLFETKSDLPYLKDGTVYMLAIRGTRVNDAKDLSADLVLLGGNKPAQADDIRKVVGEL
                     AKDISITKLYMTGHSLGCYLAQIAAVEDYQKYPDFYNHVLRKVTTFSAPKVITSRTVW
                     DAKNGF"
     gene            11542..12117
                     /locus_tag="VW883_001315"
     CDS             11542..12117
                     /locus_tag="VW883_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0274450.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSFSQPSAEPME
                     NIALGKQVTQSSTVFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12142..12654
                     /locus_tag="VW883_001316"
     CDS             12142..12654
                     /locus_tag="VW883_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0274451.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13308..14018
                     /gene="deoD"
                     /locus_tag="VW883_001317"
     CDS             13308..14018
                     /gene="deoD"
                     /locus_tag="VW883_001317"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0274452.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14041..14565)
                     /locus_tag="VW883_001318"
     CDS             complement(14041..14565)
                     /locus_tag="VW883_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0274453.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCIFRTFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14618..14854)
                     /locus_tag="VW883_001319"
     CDS             complement(14618..14854)
                     /locus_tag="VW883_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0274454.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14922..15842)
                     /locus_tag="VW883_001320"
     CDS             complement(14922..15842)
                     /locus_tag="VW883_001320"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0274455.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEIYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16032..16399
                     /locus_tag="VW883_001321"
                     /pseudo
     CDS             16032..16399
                     /locus_tag="VW883_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16615..17196
                     /locus_tag="VW883_001322"
     CDS             16615..17196
                     /locus_tag="VW883_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0274456.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGSLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17193..18470
                     /locus_tag="VW883_001323"
     CDS             17193..18470
                     /locus_tag="VW883_001323"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0274457.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18488..19150
                     /gene="deoC"
                     /locus_tag="VW883_001324"
     CDS             18488..19150
                     /gene="deoC"
                     /locus_tag="VW883_001324"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0274458.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASADKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19137..19526
                     /locus_tag="VW883_001325"
     CDS             19137..19526
                     /locus_tag="VW883_001325"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0274459.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19617..20669
                     /locus_tag="VW883_001326"
     CDS             19617..20669
                     /locus_tag="VW883_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0274460.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20813..22348
                     /locus_tag="VW883_001327"
     CDS             20813..22348
                     /locus_tag="VW883_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274461.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22341..23399
                     /locus_tag="VW883_001328"
     CDS             22341..23399
                     /locus_tag="VW883_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274462.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23402..24358
                     /locus_tag="VW883_001329"
     CDS             23402..24358
                     /locus_tag="VW883_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274463.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            24443..25791
                     /locus_tag="VW883_001330"
                     /pseudo
     CDS             24443..25791
                     /locus_tag="VW883_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         7636 a         4619 c         5827 g         7711 t
ORIGIN      
        1 actatatatc ataatggaca aagggcaagc tgtcaagaaa ttacagttat tttagtaaaa
       61 aaagaagcag aaaaatttca ttttctactc attttctata ggatttattt ttctttttca
      121 gaacttttaa cttcagcttt tttggcagat ttaatctgaa tgtttccctt gctagtcata
      181 actgctttga gatctttttc gcttggattt tcaaggtagt agtcagtgat tgtgtcctca
      241 atatagtctt gaatagtccg acgaagtggg cgtgctccca tttttgtatc ataacctagg
      301 tcaaccaact tttccttgac cttatcagtt acatccaaac gaatgttgtt gctagagagg
      361 cgcttgttaa catctgctag catgagctcg acaatctgaa ggaggttatc cttgctgaga
      421 gccttaaatt cgataatgcc atcaaaacgg ttcataaact ctgggctaaa gaagttaccg
      481 agttcaccga ggacagaatt ggtacgtcct tctctagcag caccaaatcc aacgctagct
      541 tcggtctttc ctgtacctgc atttgaggtc atgataatga tggcatcctt gaagctaacg
      601 gtgcgtcctt gcccgtctgt caaacgacca tcgtccaaga cttgaagaaa catgtgcata
      661 acatctgggt gagctttttc cacttcatcg agaaggatga gagaatatgg attgtggcga
      721 actttttcag ttaattgacc agcctcatca tagccaacat aacctggagg ggcgccgacc
      781 aacttagcca cactatgttt ttccatgtat tcactcatat caaagcgaat catactatca
      841 gcagaaccaa aaagttcgat agccagttgt ttggaaagtt ctgtcttacc gacaccagtt
      901 ggcccaacga agaggaagct tccgattggg cggttagggg taccaagtcc gacacgatta
      961 cggcgaatag ccttggcaat cttatcgact gcatcatctt ggccaataac atgagacttg
     1021 agatcttcgg ctagatggat gagttgagat tgttctttct ctttcaaatc accaacaggg
     1081 atattggttt tctgctcgat aatgtgctca atagttttct cgctgatgat aggagtatcc
     1141 tggtctgtga tctttttctt ttgcatttcc ttatacttgg caatctggtc gcggaagtag
     1201 gccgccttct caaaatcttc ttctcgtgta gcttgagact tgagattttc agcctcaatc
     1261 aagcgctgat caattacttt aggatccaca aaattcaagg tcaagttcat cttagaacca
     1321 gcttcatcta ggaggtcaat ggccttgtca ggcaagaagc gatcttggat gtagcgattg
     1381 gaaagagttg cagctgcttc aatcgcagca tctgtatatt gaacgtggtg gtaatcttcg
     1441 tatttctttt gaatcccttt gagaatagtg attgtttcgt ccaccgttgg ttcatcgact
     1501 ttaacaggct gcatacgacg ctcgagggca gcatcctttt caatgatacg gtattcattg
     1561 agggtagtag caccgactag ttgcagttct ccacgagcaa gggctggctt gaggatattt
     1621 cctgcgtcca tattaccatc actcgcagaa ccagcaccaa caatttcatg gatttcatcg
     1681 ataaagagga tgatgtcttc acgtttgcga atttcttcca tgagtttttg catgcgttct
     1741 tcaaattgtc ctcgaatccc cgttccttga actaagctaa ccacatccag acggatgact
     1801 tgtttacctt ggagtttatg tggcacatcg ccatcgacaa ttttctgagc tagaccttcg
     1861 acaacggccg tttttccgac accaggttca ccgataagga caggattatt cttggttcta
     1921 cgattgagaa tctcgatgac acggataatc tcatcgtcgc gcccaataac ggggtcaatg
     1981 tctccacgac gggcaatttc agttacatta ataccaaatt cttccagcag gcctttttct
     2041 tggctaggtg gcggagtttg agcagatcca cgattttggg aaccataacc gccgtttcca
     2101 ccgtaacctc cacctgattg ggttggggga ataggaggag tattgctaga aggtctgaaa
     2161 ttgtttagat cattgaagaa atcaccaaag ggatcgaagt cacgattgtt cagatccgtc
     2221 atacctttga agaggctatt gttaggatct gttttgataa tcttatagca gttttgacag
     2281 aggtcaattt gtttttgttt tccattgaga ttggtgtaaa gatgaattgt tgagtcgtta
     2341 attttacagt tttgacaaag catacatcta cctcatttct ttctttagcc tgacttgttt
     2401 aaaggtcaaa aatagtcaaa ttctatactc tcattataac aggattgggg tgtaaagcaa
     2461 gtaaaaagat tgaagctttg agaagttgtt acaatgaaaa tttttgtgaa tttggactat
     2521 aaaaaaatcc tatttgtgag acaaaaagga ttttacttag acatgcaggg acaatcccag
     2581 cttgttttag attagtagag aagttcgtaa atttccattg cgattaagtc aatgctatca
     2641 aacgtatacg tttcgcgatc ttctacgtca cgaagggtaa agattgggcc gttttcttcg
     2701 tcgtggctgt acgcaacttc tgcaacaaca actccttcgc gttcaaaatt acgttttaaa
     2761 tttccgccat cgtttgccat tgcttcaagg cggttgatga ttctaaccaa atgtgattcc
     2821 attttgattc tccttcattt cttatcgtta ctattttacc ataaaggagg ccaacttgac
     2881 tagaaaaaac taagatttct cgctaattct gctagtttaa agatttttaa ataaattgga
     2941 taaaaaattt aaattttaat tcaaaacatg ttataatcat acagtattct attttagaaa
     3001 gcagtgtgac tatgaatttt tcttttttac ctaagtattt accttatttt aactatgggg
     3061 ctgttgtgac gattcttatt tctatctgtg ttatcttttt gggaactatt ttgggtgttg
     3121 tcttggcttt tgggcaacgt tcaaagttta aaccgcttgt ttggttggcc aacttgtacg
     3181 tttggatttt ccgtgggaca ccgatgatgg ttcaaattat gattgccttt gctcttatgc
     3241 atatcaatgc tccgactatt cagattggaa ttttaggtgt tgatttttcg cgtctgattc
     3301 cagggatttt gattatctct atgaatagtg gtgcttatgt ttcggagatt gttcgtgccg
     3361 gaatcaatgc ggttccaaaa ggtcagctag aggcggctta ttcgctaggg attcgtccta
     3421 aaaatgcgat gcgttatgtg attttgccac aagcagtcaa aaatatcttg ccagcattgg
     3481 ggaacgaatt tatcaccatt atcaaggaca gctccctctt atcagctatt ggggtcatgg
     3541 agttgtggaa tggggctaca acagtttcta caacaaccta tctaccttta acaccacttt
     3601 tatttgcagc attttactac ttgattatga cctctattct gacagtagcc ttgaaagctt
     3661 ttgaaaaaca tatgggacaa ggagataaga aataatgaca gaaaccttga taaaaattga
     3721 aaatttacat aaatcttttg gaaagaatga agtattgaag ggcatcaacc tcgagattaa
     3781 aagaggagaa gttgtcgtta tcatcggtcc ttcagggagt gggaaatcta ccttgcttcg
     3841 ctctatgaat ttgttggagg aagcaaccaa ggggaaggtt atctttgagg gagtcgatat
     3901 tacggacaag aagaatgacc tgtttgccat gcgtgagaag atgggcatgg ttttccaaca
     3961 atttaacctc tttcctaata tgactgtgat ggaaaatatt accttgtcac ctatcaagac
     4021 taaaggtgaa agcagggaag ttgctgagaa gagagcccaa gagcttttgg aaaaagttgg
     4081 tttgccagat aaggcagacg cttatccaca gagtctgtcg ggtgggcaac aacaacggat
     4141 tgccatcgcg cgtgggttgg ctatggaacc agatgttttg ctctttgacg aaccaacttc
     4201 agccttggat cctgaaatgg taggtgaggt attggctgtt atgcaagacc ttgccaagtc
     4261 agggatgact atggttatcg taacacatga gatgggattt gcccgtgagg tggcagatcg
     4321 tgttatcttt atggcagacg gtgtggttgt tgaagatggg acacctgagc agatttttga
     4381 acaaacccaa gaacaacgga ctaaagattt cttgagtaag gttttataat ctattttaaa
     4441 atttcaagac aagattagtg aaaagttcaa ccagagcttt ttcttatagt ttgaaactat
     4501 aggataacct aggaaagaag tgttagaggg cactagcagt ttttggtata atggaagata
     4561 tttgaaagaa aagagaagtg atatgacaca gattattgat gggaaagctt tagcggccaa
     4621 attgcagggg cagttggctg aaaagactgc aaaattaaag gaggaaacag ctctagtgcc
     4681 tggtttggta gtgattttgg ttggggataa tccagccagc caagtctacg ttcgcaacaa
     4741 ggagaggtca gctcttgcgg ttggttcccg tagcgaagta gtgcgagttc cagagaccat
     4801 tactcaagag gaattgttag acctgattgc taaatataat caggatccag cttggcatgg
     4861 gattttggtc cagttgccat taccaaaaca tatcgatgaa gaggcggttt tattaaccat
     4921 tgacccagaa aaggatgtgg atggtttcca tcccctaaac atgggacgtc tttggtctgg
     4981 acatccagtc atgattccct cgacacctgc aggaattatg gaaatgtttc atgaatatgg
     5041 gattgacttg gaaggtaaaa atgcggtcgt aatcggtcgt tcaaatatcg ttggaaaacc
     5101 tatggctcag cttcttttgg ctaaaaatgc gacagtaacc ttgacccact cacgaactca
     5161 taatcttgcc aaggtggctg ctaaagcaga tattcttgta gtcgcaatcg gccgcgccaa
     5221 gtttgtgact gctgactttg tcaaaccagg tgcggttgtc attgacgttg ggatgaatcg
     5281 agatgaaaat gggaagctct gtggagatgt tgattatgag gcagttgcac cacttgctag
     5341 ccatatcacg ccagtccctg gaggtgtcgg tcctatgacc attaccatgc tgatggagca
     5401 aacttatcaa gcagcacttc ggacattgga tagaaaataa gagaagcatt cgattaatag
     5461 agtgtatttt ctatagctat atctaaaatg gcagaaatga atattaaatt ttagatataa
     5521 gattacaaaa ggaggtctgc gtctcctttt tattgtataa taaaagtgag aggaaaaaag
     5581 gatgaaagtg attaatcaaa ccttattaga aaaagttatt attgaacgtt ctcgttcaag
     5641 tcataaagga gattatggtc gtctgctgct gcttggtggt acttatcctt atggaggtgc
     5701 catcatcatg gctgctttag cagctgtaaa aagcggtgca ggattggtga ccgttggaac
     5761 ggacagggaa aatatcccgg ctctgcacag ccatttacct gagcctatgg ccttttctct
     5821 tcaagaccag caattgttaa aagagcaatt ggagaaggca gaagttatct tgctggggcc
     5881 tggtttagga gacaatgctt ttggagaaga tttagttaaa caggtctttg ctggcttaaa
     5941 acagaatcag attttgattg tagacggagg tgccttgacc attcttgcta ggacaagttt
     6001 gtcatttccc tcaagccagc ttatcctaac tcctcaccaa aaagaatggg aaaaattatc
     6061 tggaattacg attgaaaagc aaaaggaaga tgcaacggct agtgttctga cttccttccc
     6121 tcaaggaaca attttggtgg agaaaggccc agctactcgt atttgggaag ttggccaatc
     6181 tgattattac cagttacagg ttggtggtcc ttatcaggcg actgggggaa tgggagatac
     6241 tctggctggg atgatcgcag gatttgtagg ccaattccga caggccagtc tctacgagcg
     6301 tgtggcagta gcgacccatc ttcattcagc catagcccaa gaactatctc aagaaaatta
     6361 tgtggtctta ccgacggaaa tcagcaggta tcttcccaaa ataatgaaaa ttatttgtca
     6421 acaagagagg gtaagcaaag ataaacttgt ttaaaataga cagataaatc tacttccttc
     6481 tcttaattta tgattcttga aatgcgcctg ctttaaggct aaactagacg tatcaaagtt
     6541 aagagtttgt ttttgtaact ggaaagagat gaacaaatca aatacataaa agataaactc
     6601 atttttattc gtttggtaaa aataaaatgc atatttttaa agaaagattg atgaaaaatg
     6661 tagatttgat gtttttactt gaataaaaag cggtttcata gtaaaataag aactgagaat
     6721 gatggaggta aatcggtgga aaatctgaag aaaatggcag gtatcaaggc tgctgagttc
     6781 gtgagcgatg gaatggtcgt tggacttgga acaggctcga ctgcctatta ttttgtcgaa
     6841 gaaatcggtc gtcgtatcaa ggaagaagga ttgcagatta cagctgtaac aacttctagt
     6901 gtgaccacta aacaggcaga aggccttaat atcccgctca agtctattga ccaagtagac
     6961 tttgtcgatg tgacggttga tggcgcggat gaagtggata gtcagtttaa tggaatcaaa
     7021 ggcggtggtg gtgcccttct catggaaaag gtggtcgcaa caccatcaaa agaatacatt
     7081 tgggtggtgg atgaaagcaa gctggtcgaa aaactaggtg cttttaaatt gccagtagaa
     7141 gtggttcagt atggtgcaga gcaggtcttt cgtcattttg aacgagctgg ctacaaacca
     7201 agtttccgtg aaaaagacgg ccaacgtttt gtgacggata tgcagaattt tatcattgac
     7261 ctcgccttgg atgtcattga aaatccaatt gcttttggac aagaattgga ccatgtcgtt
     7321 ggtgttgtgg agcatggttt attcaaccaa atggtggata aggtaatcgt tgctggacga
     7381 gatggagttc agatttcaac ttcaaaaaaa ggaaaataga agggggcata agatgtctaa
     7441 atttaatcgt attcatttgg tggtactgga ttctgtagga atcggtgcag caccagatgc
     7501 taataacttt gtcaatgcag gggttccaga tggagcttct gacacactgg gacacatttc
     7561 aaaaacagtt ggtttgaatg tcccaaacat ggctaaaata ggtcttggaa atattcctcg
     7621 tgaaactcct cttaagactg tagcagctga aagcaatcca actggatatg caacaaaatt
     7681 agaggaagta tctcttggta aggatactat gactggacac tgggaaatca tgggactcaa
     7741 cattactgag cctttcgata ctttctggaa cggattccca gaagaaatcc tgacaaaaat
     7801 cgaagaattc tcaggacgca aggttattcg tgaagccaac aaaccttatt caggaacggc
     7861 tgttatcgat gattttggac cacgtcagat ggaaactgga gagttgatta tctatacttc
     7921 agctgaccct gttttgcaga ttgctgccca cgaagacatt attcctttgg atgaattgta
     7981 ccgtatctgt gaatacgctc gttcgattac ccttgagcgt cctgcccttc ttggtcgcat
     8041 cattgctcgc ccttatgtag gtgaaccagg taacttcact cgtacggcaa accgtcgtga
     8101 cttggctgta tctccatttt ccccaactgt tttggataaa ttgaatgagg ctggtatcga
     8161 tacttatgct gtgggtaaaa tcaacgatat ctttaacggt gctggtatca accatgacat
     8221 gggtcacaac aagtcaaata gtcatggaat tgatacacta ttgaagacta tgggacttgc
     8281 tgagtttgaa aaaggattct cattcacaaa cctagttgac tttgatgccc tttacggcca
     8341 tcgtcgtaat gctcacggtt accgtgattg cttgcatgag tttgatgaac gcttacctga
     8401 aattatcgca gctatgagag agaatgacct tctcttgatt actgcggacc atggaaatga
     8461 cccaacgtat gcaggaacgg atcacactcg ggaatatatt ccattgttgg cctatagccc
     8521 tgcctttaaa ggaaatggtc tcattccagt aggacatttt gcggatattt cagcgactgt
     8581 tgccgataac tttggtgtgg aaactgctat gattggggaa agtttcttag ataaattggt
     8641 ataagatgac gcgctatgct ttgctggtga gaggtatcaa tgttggtggt aagaataagg
     8701 tcgtcatggc ggagcttcgt caagaattga caaacttggg actggaaaag tttgagagct
     8761 acatcaacag tggcaatatt ttctttactt cgatagattc caaagcccaa ttggttgaaa
     8821 agctagagac tttctttgca gtccattatc catttattca gagcttttct ttactgagtc
     8881 tagaggactt tgaggcggaa cttgaaaatc taccagcttg gtggagcaga gacttggcac
     8941 gaaaagattt tctcttttac actgagggtt tggatgtgga ccaagtcatc gcgacagttg
     9001 aaagtttaga gctgaaagat gaagtgcttt attttggaaa acttgggatt ttctggggga
     9061 aattttctga agaatcctat tctaagactg cctatcataa gtacttgctg aaggtgcctt
     9121 tctaccgcca cattactatt cgtaatgcta aaacctttga caaaattggt caaatgctaa
     9181 aaaaataata aaggagacac acaatgacat ttttaaacaa aatccatgaa actgctactt
     9241 tcctgaaaga aaagggaatt gcagcccctg agttcggtct aatccttggg tcaggacttg
     9301 gagaattggc agaagaaatc gaaaatccag ttgtagtaga ctatgctgag attccaaact
     9361 ggggccgttc aacagtagtc ggtcatgctg gtaaattggt atatggtgaa ctggcaggtc
     9421 gcaaggtctt ggctcttcaa ggtcgtttcc atttctatga agggaatcct ctggaagtgg
     9481 tgactttccc agttcgtgtg atgaaagttc ttggatgtga aggtgttatt gtaaccaatg
     9541 cagctggcgg tatcggattt ggtcctggta ccttgatggc tatctcagac catatcaaca
     9601 tgacggggca aaatccattg atgggtgaaa acttggatga ctttggccca cgtttcccag
     9661 atatgtctag ggcctacaca ccagaatacc gtgccactgc ccatgaagtg gctaaaaaac
     9721 ttaatatcaa gcttgatgaa ggtgtctata tcggagttac tggtccgact tatgaaacac
     9781 cagcagaaat tcgttcctat aagacactgg gagcagatgc agttggtatg tctacggttc
     9841 ctgaagttat cgtggcagcc cactctggct tgaaagttct gggaatttca tgtatcacta
     9901 actttgcggc tggtttccaa gaagaactca atcacgaaga agttgtagaa gtgactgaac
     9961 gtgttaaagg tgatttcaaa ggcttgctta aagcgattct tgctgaattg taagaaaaaa
    10021 gatttaaaag gggaagtgcc tctgtttttt caggattgac tgcctatccg gattaaagaa
    10081 gaaacagagg aatactatga gcttcttcct gctcttataa ctgaaagaag cggaagaata
    10141 ggtatgtctg atctgatagc cagcattgtg aaagacaaga ttctaggata ctagcattag
    10201 ctttctagcc aagcagacta gtatgataag gagagatgag aatgaattga ctttctgaat
    10261 ttctcagtct tatcatatat agcacaatga gatttcgctt gagtctgctt gtaaataaac
    10321 gaaaagaaag ataagaaata atgaaaattg gtcaacgaat tatgcgcttt ggcataaaaa
    10381 attaagtatc ggagttgtat ctgttgtagt cggctttgat ttctagctcc agctggaatt
    10441 tcagccaatg aagtaaagca agatgtaaca tttgaagtgg taataggtgt gctagattct
    10501 aaggaggaat tgaaagagtc agaaaatgat gctccaaaac tagaaactcc tcttagagag
    10561 gagccaagac tagctcctca aacgcttccg gaagcaagtg aagttcttga aaacaaaagg
    10621 gaagagtcaa aagtagagat aacagagcca gctcaagact cacctattct tgctcctgta
    10681 gaagaaacta aagaagaagc tgtgacagaa aaaccaacaa atactcgttc tctaactgca
    10741 gaagatttgg tgaagatttc caaaggggaa ttgcatttag aaaatgattt gattgatgaa
    10801 tctttctatg gtgaaaaagc tcttgatttg gaaggggatg atgaccagga tggcatcaaa
    10861 aacaaagatg gtaaggatta tctaggatat aacagtcatc ccttgctagc agacagtgat
    10921 ggggatggtt tggcagatgg ggaagatgat aataagaaag aatggtatgt cacagaccgt
    10981 gattctcttc tctttatgga gttagcttat cgagacgatg attatattga gaaaatttta
    11041 tatcataaga atcttttccc tagtctctat cttgaccgtc aagaacacaa actcatgcac
    11101 aatgaattgg ctcctttctg gaagatgaaa aaagcctact atacagatag tggcttggat
    11161 gctttcttat ttgagaccaa gagcgacctt ccttatctca aagatggaac ggtgtacatg
    11221 ttggctattc gtggaacgcg agttaatgac gccaaggact tgagtgcaga tttggtttta
    11281 ttaggtggaa ataaaccagc tcaagcggat gatatccgca aggttgttgg ggaattagcc
    11341 aaggatataa gtattactaa gttgtatatg acaggtcatt ctcttggatg ctacctagct
    11401 cagattgcag cggttgaaga ttaccaaaaa tatcctgatt tttataacca tgtattgagg
    11461 aaagtgacaa ctttcagtgc tcctaaagtc attacttcca gaactgtttg ggatgctaag
    11521 aatggtttct gagatgttgg tttggaaagt cgtaaattag ctgttagtgg aaaaattaag
    11581 cattatgtgg ttgataatga caatgttgtg actcccttga ttcataataa tcgtgatatt
    11641 gttacattta caggtaattc acgctttaaa caccgttctc gtggctattt tgaaagtcca
    11701 atgaatgata ttcctaactt taatattggt aaacaagcta ccttggataa acatggttat
    11761 cgtgatccga aattggataa agtgcgattc tttaagaaac aggctctgcc tcgatctttt
    11821 agtcaaccaa gcgctgaacc aatggaaaat attgccttag gaaaacaggt tactcaaagt
    11881 tcgacagttt tcggaggaga tgctagaaga gctgtggatg gcaaagtcga tggtaactat
    11941 ggtcacaatt ctgtcactca tacaaacttc caatctaagc cttggtggca agtagatttg
    12001 gctaaagaag aaaccattcg ccaaatcaat atttacaacc gaacagacac tgcccaggat
    12061 agattggcaa actttgatgt cattctttta gacagttctg gtaaagaaat tgagtgaaaa
    12121 cgtataacat ctcctaaaga tgtgtcagca caaattacga ttaaccataa aaaagtgcgc
    12181 tatgttcgga ttgagctaga aggctataat gccctcagtc ttgcagaagt tgaagttttc
    12241 cgctttatag ctacgaatgc tgaaacggcg acacaagttt ctaagccagt tcaaccaatc
    12301 agtcagactc ctgtgaaaga taaaacattg acaattcaac acagtggagc ttacattgcc
    12361 cgctactcca taacttggga agaagttcca gtagataaag atggaaacca agttgttcgt
    12421 agtcattctt gggaaggaaa cggttgcaac cagactgcag gttttgtcct caacctccca
    12481 atcaaagaaa atatgagaaa tctgcgagtt aagattgaga aaaagacggg cctactatgg
    12541 aatagatggc aaacaatcta tgaaaacaga ccaattttag ctcaacccca ccgtaaaatt
    12601 acccattggg gtacgacatt gaattccaag gtgagtgacg atgatgtctt gtaatctgat
    12661 ggtacaatga cagttagttt gtctagttta taagaaagta ctacctgagc ttgaatagaa
    12721 ctcaggtagc tctctgtgaa agaacaaaat taatactcaa tgaaaatcaa agagcaaact
    12781 aagaaactag ccgcaggttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa
    12841 gtcagtcaca tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    12901 ataaacagaa aggtagagcg cgtgttctaa tttgaacacg agtagaaaac ttttctaaaa
    12961 acaaaaacga aaggatgggt aaactgtatt cgctgaactg aatacgggcg actctcctct
    13021 aaatcaaaat taagaaagga attgacccca ccctaaaagt agtgggaaaa agatagttga
    13081 tctagcgagc atcgctcact gcgcccaact cctattttcc cttcgctttt tgatgggttt
    13141 ggtatctttc tcaatataaa atataaaata aagaaaggta gagcgtgtgt tttgatttga
    13201 acacgagcgg aaaactcgga aaatagataa tctgactgaa aaatcaggat ttctcgtcag
    13261 gttcctaatt ttcagtcgtt ttcttctcgc tctttgtatc ataaattatg tctatccata
    13321 ttgctgctca gcagggtgaa attgctgata aaattcttct tcctggggat cctcttcgtg
    13381 ctaagtttat tgcggagaat ttccttgatg atgctgtttg ttttaacgaa gtgcgtaaca
    13441 tgtttggtta cactggtact tacaagggtc actgtgtatc tgtcatggga actgggatgg
    13501 gaatgccatc tatttcgatt tatgcgcgtg agttaatcgt agactacggt gtgaagaaat
    13561 tgattcgtgt gggaactgca ggttctttga atgaagaggt tcatgttcgt gaattagttt
    13621 tggcgcaggc ggctgcaacc aactcaaaca tcgttcgtaa tgactggcca cagtacgatt
    13681 ttccacaaat tgctagcttt gatttgcttg ataaagccta ccatatcgcc aaagaacttg
    13741 gtatgactac tcacgttggg aacgttttgt catctgatgt cttttactca aattactttg
    13801 aaaagaatat cgagcttggt aaatggggag tcaaggctgt ggaaatggaa gcagcagctc
    13861 tttactatct tgctgcccaa taccatgttg atgcgctagc tatcatgacc atctctgata
    13921 gcttggtcaa tccagacgaa gacacaactg cagaagaacg tcaaaatacc ttcactgata
    13981 tgatgaaggt tggtttggaa accttgattg cagaataatt atagccaaaa aggaagccct
    14041 ttatgaattg taggacttcc ttttcttatc cagaaattga tctagctctc tctgatttcg
    14101 aagaatagtg actttatgtg aatattcttg gcaaagtttt tggtaatttt ctttttgagt
    14161 tttgctacgc ccatcccaaa gaatccatct gataaactcc cagtcaaagc gttcagggca
    14221 atctgccgcc atactttctc tgacttttcc acggtattta agataacgct taaaggttct
    14281 aaagatacag gtcaatggcg aaaaattgag aaagatgatt tggtcagctt cttgcattcg
    14341 ttcttggtag tagcaccaag aataattacc atcgatgacc caagctttat gcttggtgag
    14401 aaagtttttt atctcggtta acatccattc gtggtcactg tcttgccaac caggttgaaa
    14461 ttggagtgtg tccatgtgca gttttggaat ggagtagtag ttagataact tttctgctag
    14521 agttgactta ccagaaccag aatatccgat aattgcgatt ttcattttct accttttcct
    14581 atttggagac aaaaaaacag cctctatgga ctgtttctta tttagcaagt ttagctgaaa
    14641 gacgagcttt atcgcggctt gctttgtttt tgtgaatcaa acctttagtt tctgctttat
    14701 cgatagctga gctagcagca cggaaaagtt cttcagatgg gtttgcttcg aaagctttta
    14761 tagcagtacg catagctgat ttttgagctg agttcttttc gttttgttta acgttcaatt
    14821 cagcgcgttt gatagctgat ttaatgtttg ccaatgttct tacctccata tttactaact
    14881 ataccattat atatgaaaac ttacgttttg acaagggaaa attacttttt taagtaaatt
    14941 tcatcgattt catggttctt gcttttatga agaatcactt ctgcacgatt tctggttggt
    15001 tcaatataat tttgcagatt tgtgagattg atactgatcc agacctgatg ggcaaaggac
    15061 tccacttccc caatcggcat ctgagtaaaa cgataatagt agctatcagg gtcgttttgg
    15121 gctaggctca gcattttcaa gaaacggtcc agataccaac tttcaatatc atccactcca
    15181 gcatctacat agatggaaaa atcaaagaag tcagtgatat agagacgatc gttttgtgga
    15241 ttttgaaaga cattgattcc ctcaacaatt acaaaatcag cagctttgac actttgtttc
    15301 tcttcgggta cgatgtcgta aatttcatga gaatagacag gaatatctac atcttgtcca
    15361 tttttgatgc ggtccaagaa gttgagaaga gcttccatat catagctttc aggaaatcct
    15421 ttacgattta aaatcccctg ctcaatcaag gtttgattgg gatagagaaa accatcagtt
    15481 gtaaccaact caaccgtagc atctgtaaac gtacgggaca gtaggatttg aagtaggcga
    15541 ctggttgtgg attttccaac ggcaacactc ccagaaaccc caataataaa aggttgagat
    15601 ttactttcac gttggaggaa aattcctttt gaaaaggcta aatcttcctt agttcgcttg
    15661 taaatctgaa tcagatgagc caaggggaga tagatatctg taacgtcttg gagactgatt
    15721 tggtcattaa aactcttgat agattccaat tcttcttctg tcaaaggagg tgttgttttt
    15781 cgatgtaaag attgccaagt ctggcggctg attttttcaa aatgtaaaaa ttcgttggtc
    15841 atttgttttc ccctagatat tttgtctatc ataccataaa aatctaaaaa aataaagcga
    15901 tttcttgaat gtggtaagtc aatggtatat aatataagtg atcaatttat tgatgaaata
    15961 ggagatagat tctactgatt tataagctta taaagggggc tttttagttc acaacttata
    16021 ggaggtgtac tatgaaaatc ttaaaacgtt acatattgga actctgtttt attttaagtt
    16081 ttgctttacc ttttataaaa ggagccaatg cagataatgg tagatgcttt gtggaaacct
    16141 attacggttt tacttttttg atggaacatg ctattgtaac agctgtcttt atctgttcgt
    16201 tcttaattgc tgtcttacta aaaaacgatg ggcgaaatgg attgcgacag agggttattt
    16261 cttccacatg tcaccagaag atttgatacg actttggaca agtttggaaa tcctgacaca
    16321 aacgtatcag ttgggctttt atctaaacat tttgttggga attttgttga taataaagta
    16381 ttttaaggtt aagcaataga aataataatc tgcctgatta tagatgataa actttttgtt
    16441 tttatctgga ctgtgatatt tatagttcta aatggtttat tatttataag tgttgaaaga
    16501 gattgaagaa aatggcttcg tgactcgctt tcttcggtct ttttcgtttt attatcaatt
    16561 tgtaaacgat ttacaatttg agtcaaatta tggtaaaata gtgtcatgag taaaatgtat
    16621 tatgcagaaa atcctgacgc tgctcacgac attcatgagt tgagagtaga gttgttggga
    16681 caaaaaatga cctttttaac ggatgcgggt gtttttagca agaaaatagt tgactttgga
    16741 agtcaactat tgctcaagtg tcttgaggtc aaccaaggag aaactgtcct tgatgtaggc
    16801 tgtggttacg gatctttggg tttgtcctta gctaaggctt atggagttca ggctactatg
    16861 gttgatatca acactcgtgc cttggattta gctcggagaa atgctgaaaa aaataatgca
    16921 aaagcgacga ttttccagtc caacatctat gaacaagttg aaggacattt tgatcatgtc
    16981 atttccaatc ctcctatccg tgcgggcaag caagtcgttc atgaaatcat tgagaaaagt
    17041 aaagatttct tggaaactgg tggggatttg acaatcgtca tccagaaaaa acaaggggct
    17101 ccaagtgcta agtccaagat ggaggatgtg tttggtaatt gtgaaatcct taaaaaagac
    17161 aagggatact atatccttag aagtgtgaaa gaatgagagc agttgattta atccaaaaaa
    17221 aacgagacgg tcaagaactg acttcaagtg aaattgaatg gctggtagaa ggctatgtgt
    17281 caggaactgt tcctgattat cagatgtctg cctttgctat ggctgtttat tttaaaggaa
    17341 tgacgactcg tgaaatttct gatttaacga tgaatatggt taagactggg caagagtttg
    17401 acctgtcagc cattgatggt gtgaaagttg acaagcattc tactggtggt gtcggcgata
    17461 aggtaacctt gattttagct cctcttgttg ctagcttcgg tgtgcctgta gcaaaaatga
    17521 gtggtcgtgg tcttggccat acaggcggaa caattgataa attggagtcc attaggggct
    17581 atcaagtaga acgtagtcaa gaggatttta ttcgtcaggt tcaggatatt ggagtatctg
    17641 tcattgggca atcagaccag ctggtcaaag cagataagct tctctatgcc cttcgtgatg
    17701 tgaccgcaac tgtcgacacg attcctttga ttgcgagttc ggtgatgagc aagaaaatcg
    17761 cggcaggggc ggatgctatt ttgctagatg tgactgtcgg tgagggtgcc ttcatgaaga
    17821 cggttgatga ggcgcgtgag ttggctcaaa ctatggtaga tcttggtaag gttgttggac
    17881 ggaagacagt agcagtgatt acggatatga gccagcctct gggacgagcg attggaaatc
    17941 gtctggaaat ccttgaagca ttggagattt tgcaaggtca aggacgtcag gatattaccc
    18001 actttatttg tgaattggct caaattatgc ttggtttggc aaatgttaac aagactgttg
    18061 aagaagttcg ccaacatctt gagaatggtc aagcactggc taagtttgag gaaatggtgc
    18121 aagcccaagg tggagacttg gaagacctct atcgtcctgt aaatgtagct catgtggtgg
    18181 aaatccctgc tcaggaaacg ggtgtcattt cagctcttcc agctatggac tttggtcttt
    18241 atgccatgag gctgggtgct ggtcgtgcag ttaagtctga tgccttggac tatgaaacag
    18301 gaattgtttt tgaaaagaag attggagact ccgttcaaaa gggtgaaatt gttgcaaaag
    18361 tatacacaaa tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa tgtgttaaaa
    18421 taagtgatga agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa atggagggaa
    18481 aaccgaaatg aaattaaata aatatataga tcatacgctt ttaaaacaag atgcaaagaa
    18541 aaaacaaatt gatagtttgt tgtctgaggc tagagagtat gactttgcca gtgtttgcgt
    18601 taatccgacc tgggttgaac atgctaaaaa aggacttgaa ggcacagatg ttaaggtttg
    18661 cacagtagta ggtttccctt tgggagcaac aacttcagcc gtgaaagcat ttgagacaaa
    18721 agaagctatc caaaatggtg cagatgagat tgatatggtg atcaatgttg gagctctcaa
    18781 atcaggtaat ttagccttgg ttgagtcaga tattcgcgca gtagtggaag caagtgctga
    18841 taagttagtg aaagtcatta ttgaagcttg ccttctgaca gaccaagaaa aaattgttgt
    18901 ttgccaattg gcccaaaaag ctggggctga ctttgttaaa acatctactg gtttttcaac
    18961 tggtggtgct acgatagcag atgttacatt aatgcgtgaa acagttggat ctgatatggg
    19021 agtcaaggct gctggtggag ctcgttctta tgcagatgct cttgcctttg tcgaagcagg
    19081 tgcgacccgt atcggaacgt cagctggggt agctatttta aaaggagaat tggcagatgg
    19141 cgactactga gttgattgaa ctggcaattg aaaccagcaa acatgcctat gtcccctatt
    19201 ctcactttcc tatcggagca gttttagtag ccaaagacgg aaatgtttac acgggagtga
    19261 atatcgaaaa tgctagctat cctttgacca attgcggtga gagaacagct atttttaagg
    19321 ctatatctga aggccaaaga gaattttcag aattgattgt ctatggtcaa actgaaaaac
    19381 cgatttcacc atgtggtgct tgtcgccaag taatggtcga attttttgaa caagatttaa
    19441 aagtgacctt agtcgcaaaa gataaatcga cggtcgagat gacggtcggg gagttacttc
    19501 catattcttt tacagactta aattagtctg agtcgctctt tgagtggcaa gggtctttgt
    19561 gaccaatcaa tccatacttg caacatcgtt gcacatctta tttaggaggt tcagtaatga
    19621 acaagaaaca atggctaggt cttggcctag ttgcagtggc agcagttgga cttgctgcat
    19681 gtggtaaccg ctcttctcgt aacgcagctt catcttctga tgtgaagaca aaagcagcaa
    19741 tcgtcactga tactggtggt gttgatgaca aatcattcaa ccaatcagct tgggaaggtt
    19801 tgcaggcttg gggtaaagaa cacaatcttt caaaagataa cggtttcact tacttccaat
    19861 caacaagtga agctgactac gctaacaact tgcaacaagc ggctggaagt tacaacctaa
    19921 tctttggtgt tggttttgcc cttcacaatg cagttgaaga agcagctaaa gaacacactg
    19981 acttgaacta tgtcttgatt gatgatgtga ttaaagacca aaagaatgtt gcgagtgtaa
    20041 ctttcgctga taatgagtca ggttaccttg caggtgtggc tgcagcaaaa acaactaaga
    20101 caaaacaagt tggttttgta ggtggtatcg aatctgaagt tatctctcgt tttgaagcag
    20161 gattcaaggc tggtgttgcg tcagtagacc catctatcaa agtccaagtt gactacgctg
    20221 gttcatttgg tgatgcggct aaaggtaaaa caattgcagc cgcacaatac gcagccggtg
    20281 cagatattgt ttaccaagta gctggtggta caggtgcagg tgtctttgca gaggcaaaat
    20341 ctctcaacga aagccgtcct gaaaatgaaa aagtttgggt tatcggtgtt gaccgtgacc
    20401 aagaagcaga aggtaaatac acttctaaag atggcaaaga atcaaacttt gttcttgtat
    20461 ctactttgaa acaagttggt acaactgtaa aagatatttc taacaaggca gaaaaaggag
    20521 aattccctgg cggtcaagtg atcgtttact cattgaagga taaaggggtt gacttggcag
    20581 taacaaacct ttcagaagaa ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg
    20641 atggaagcgt aaaagttcct gaaaaataat ggatggaagt catttcttag gaagcggcca
    20701 agggccgctt ttttaagagt tgagacaaag tcattttgtc tcagtaaagc ttgctactag
    20761 acaaactagc aagttttatt gaaataaaat aagactctga aaggaagagc acatggcaca
    20821 cgaaaatgtc attgagatgc gtgatattac caaggtgttt ggtggatttg ttgctaacga
    20881 caaaatcaac ttgcacctac gaaaaggtga aattcatgca cttttaggag aaaatggggc
    20941 tggtaagtcc acgctaatga acatgttagc agggcttctt gaaccaacta gtggtgaaat
    21001 cgcggtcaac ggtcaagttg tcaatctcga ctccccatct aaagcagcta gcttgggaat
    21061 cgggatggtt caccagcact ttatgttggt tgaagccttc acagtggctg aaaacatcat
    21121 tttaggtagt gaattgacta aaaatggtgt gctagatatc gctggagcta gcaaagaaat
    21181 caaggctctt tctgaacgtt atggcttagc tgttgaccct tctgccaagg tagcagatat
    21241 ctcagttgga gcccaacaac gtgtagaaat tttaaaaaca ctttatcggg gggctgatat
    21301 ccttatcttt gacgaaccaa cggctgtttt gactccatca gaaattgatg agttgatggc
    21361 tattatgaaa aatcttgtca aagaaggaaa atcaattatc ttgattaccc acaaattgga
    21421 tgaaattcga gcagtttctg accgtgttac agttatccgt cgtgggaaat caattgaaac
    21481 cgttgaaatt gcaggggcta ccaatgctga tttggcggaa atgatggtag gacgttctgt
    21541 ttcctttaaa acagagaagc aagcctctaa accaaaagaa gtggttttgt ctatcaaaga
    21601 tttggtggtc aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct tggatgttcg
    21661 tgctggagag attgttggta ttgcggggat tgatggaaat ggtcagtctg aactgattca
    21721 agccattaca ggtcttcgta aggttgaatc tggtagcatt gagctaaaag gagattcaat
    21781 tgtaggcttg cacccacgtc agattacaga actaagtgtt gggcacgttc cagaagaccg
    21841 tcaccgtgat ggcttgattt tggaaatgat gatatctgaa aatattgccc ttcaaaccta
    21901 ctataaagaa ccacatagta aaaatggaat tttgaattat tcaaatatta cttcttatgc
    21961 taaaaagctg atggaagagt ttgatgttcg cgctgccagt gaattagttc ctgcagctgc
    22021 actctcagga ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc gagatcctga
    22081 tctccttatc gttagccagc caactcgtgg gttggatgtc ggtgccattg agtatatcca
    22141 caaacgcttg attgaagagc gtgataatgg caaggctgtc cttgttgtca gctttgaatt
    22201 ggatgagatt ttaaacgtct cagaccgtat tgccgttatc cacgatggta agattcaagg
    22261 tattgtatca ccagaaacaa ccaataaaca agaacttggt gtcttgatgg ctggtggaaa
    22321 cttgggaaag gagaagagtg atgtctaaaa aattacaaca aatttcggtt cccttgattt
    22381 ctgtatttct aggaatttta ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta
    22441 tttggggcta cgaagaattg ttctatacag cctttggcag tctgcgtggg attggagaaa
    22501 tcttccgtgc tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag
    22561 ctggtttctt taacgtcgga cttcctggtc aggctttggc aggttggatt ctcagtggtt
    22621 ggtttgcgct gtcgcatcca gatatgcccc gtcccttgat gattctagca accatcgtga
    22681 ttgccttgat tgctggtggg attgtcggag cgattccagg tattcttagg gcctatctag
    22741 ggacgtcaga ggttattgta accatcatga tgaactacat tgtcttgtat gtagggaatg
    22801 cctttatcca tgctttccct aaagacttca tgcaaagtac agattcgacc attcgtgttg
    22861 gggctaatgc aacctatcag acaccttggt tggctgagtt gactggtaac tcacggatga
    22921 atattggtat tttctttgcc atcattgccg ttgcagttat ttggttcatg ctcaagaaaa
    22981 caactcttgg ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca gaatatgctg
    23041 gtatttctgc caagcggact attatcctat ctatgattat ttcaggtgcc ttggcaggtc
    23101 ttggtggagc tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat
    23161 tagctatcgg atttaacgga atggcggtta gtttgcttgc ggccaactca ccaattggta
    23221 tactctttgc agccttccta tttggcgttc tccaagttgg ggctcctggt atgaatgcgg
    23281 cgcaggtacc atctgagctt gtcagcattg taacagcgtc tattatcttc tttgtcagtg
    23341 ttcattacct tatcgaacgc tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa
    23401 gatgtctatt ataaccttgc tccccctctt ggtgtcttct atgctgattt actcagcacc
    23461 tctcatcttt acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg
    23521 ccttgaagga attatggtta tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc
    23581 agaacaattt ggagcagcaa ctccatggct atccttgctt gtagcaggat tggttggtag
    23641 tgttttctct atcatccacg cagcagcgac ggttcatttc cgtgcagacc atgttgtcag
    23701 cggtacggta ttgaacttga tggcgcctgc cttggctgtt ttcttagtta aagttcttta
    23761 taacaaagga caaaccgaca acctaagtca aacttttgga cgctttgatt tcccagtctt
    23821 ggcaaatatc ccagtgattg gtgatatctt cttcaagtca actagtctac ttggttatct
    23881 ggcgattgcc ttctcattcc ttgcttggtt tattctcttt aagactcaat ttggtcttcg
    23941 tctccgctct gtcggtgaac atcctcaagc agcggatacc ttgggaatca acgtctacaa
    24001 gatgagatat ttaggggtta ttatttcagg ttttctaggt ggaattggcg gagcgattta
    24061 tgcgcaatca atctcagtta acttctcagt gacaactatt gttggacctg gatttatcgc
    24121 ccttgctgcg atgatctttg ggaaatggaa tccaatcggt gctatgcttt ctagtctctt
    24181 ctttggactt tcacaaagtt tggctgttat cggttctcaa ttgccgttcc tacaaggagt
    24241 gccagcggtt tatcttcaaa ttgcacctta tgttttgaca attcttgtct tagcagcctt
    24301 ctttggaaaa gcagtcgccc caaaagcaga tggtatcaac tacatcaaat caaaataagc
    24361 atacaaaaaa acgtcagtcc aatgactgaa ctacccccca aaagttagac agaaaaaatc
    24421 taacttttgg ggtgttttta ttatgaaact aacttatgat gataaagctc agatctatga
    24481 acttagaaaa caaggatata gcttagagaa gctttcaaat aaatttggga taaacaattc
    24541 taatattagg tacatgatta aattgattga tcgttacgga atagagttcg tcaaaaaagg
    24601 aaaaaatcgt tactattttc ctgatttaaa acaagaaatg attaataaag tcttacatga
    24661 aggctgaact aaagatagag tttctcttga atacggcctc ccaagtcgta cgatacttct
    24721 taattggcta gcacaataca agaaaaacgg gtatactatt gttgagaaaa caagagggag
    24781 agtacctaaa atgggacgta agccacaaaa gagacctgaa gagaggacag aattagaacg
    24841 tcttcaatca gaaaatgagt acctgagagc ggagaatgcc atcctaaaaa agttaagaga
    24901 actccgattg aaggaggaaa aagagaaaga agaaagacag aaattgttca agaattaatg
    24961 actgagtttt cgttagttct tcttctaaaa tccattaaac tagctcgttg gacctactac
    25021 tatcacttga aacagctaga caaaacagat aaggaccaag agcttaaagc tgaaattcaa
    25081 tccattttta tcgaacacaa aggaaattat gcttatcgcc gggttcattt agaactaaga
    25141 aatcgtgctt atctggtaaa tcataaaaga gttcaaggct tgataaaagt actcaattta
    25201 caagctaaaa tgcgacagaa acgaaaatat tcttctcata aaggagacgt tggcaagaag
    25261 gcagagaatc tcattcaagg tcaatttgaa ggctctaaaa caatggaaaa gtgctacaca
    25321 gatgtgactg aatttgccat tccagcaagt actcaaaagc tttacttatc accagtttta
    25381 gatggcttta acagcgaaat tattgctttt aatctttcaa cttcgcccaa cttagaacaa
    25441 gtgaagagta tgttagaaca ggcctttaca gagaaatact atgagaatac gattctccat
    25501 agtgaccaag gctggcaata ccgacacgat tcttatcatc ggttcctaga gagtaaggga
    25561 gttcaagcat ccatgtcacg taagggtaac agcccagaca atggtatgat ggagtccttc
    25621 tttgggattc tgaaatcgga aatgttttat ggctatgaga aaacatttaa atcacttaat
    25681 caattggaac aagctattgt agactatatt gattactaca acaataaacg aattaaggta
    25741 aaactaaaag gacttagcct tgtgcaatac agaactaaat ccttcggata aat
//
LOCUS       DAVKXA010000031        24770 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKXA010000031 DAVKXA010000000
VERSION     DAVKXA010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24770
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.031"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(34..231)
                     /gene="blpI"
                     /locus_tag="VW883_001331"
     CDS             complement(34..231)
                     /gene="blpI"
                     /locus_tag="VW883_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV0274464.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            513..1100
                     /locus_tag="VW883_001332"
     CDS             513..1100
                     /locus_tag="VW883_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV0274465.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1027..2670
                     /locus_tag="VW883_001333"
     CDS             1027..2670
                     /locus_tag="VW883_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0274466.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLIMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2681..4042
                     /locus_tag="VW883_001334"
     CDS             2681..4042
                     /locus_tag="VW883_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0274467.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4099..4227
                     /gene="blpC"
                     /locus_tag="VW883_001335"
     CDS             4099..4227
                     /gene="blpC"
                     /locus_tag="VW883_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0274468.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(4298..5638)
                     /locus_tag="VW883_001336"
     CDS             complement(4298..5638)
                     /locus_tag="VW883_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0274469.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5652..6389)
                     /locus_tag="VW883_001337"
     CDS             complement(5652..6389)
                     /locus_tag="VW883_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274470.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6394..6732)
                     /locus_tag="VW883_001338"
     CDS             complement(6394..6732)
                     /locus_tag="VW883_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274471.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7008..7337
                     /locus_tag="VW883_001339"
     CDS             7008..7337
                     /locus_tag="VW883_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0274472.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7505..8554)
                     /locus_tag="VW883_001340"
     CDS             complement(7505..8554)
                     /locus_tag="VW883_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274473.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8551..9282)
                     /locus_tag="VW883_001341"
     CDS             complement(8551..9282)
                     /locus_tag="VW883_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274474.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9350..9760
                     /locus_tag="VW883_001342"
     CDS             9350..9760
                     /locus_tag="VW883_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0274475.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9770..10057
                     /locus_tag="VW883_001343"
     CDS             9770..10057
                     /locus_tag="VW883_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274476.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10391..11527)
                     /gene="dnaJ"
                     /locus_tag="VW883_001344"
     CDS             complement(10391..11527)
                     /gene="dnaJ"
                     /locus_tag="VW883_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0274477.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11929..12285)
                     /locus_tag="VW883_001345"
     CDS             complement(11929..12285)
                     /locus_tag="VW883_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0274478.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTRY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12287..14110)
                     /gene="dnaK"
                     /locus_tag="VW883_001346"
     CDS             complement(12287..14110)
                     /gene="dnaK"
                     /locus_tag="VW883_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0274479.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14590..15123)
                     /gene="grpE"
                     /locus_tag="VW883_001347"
     CDS             complement(14590..15123)
                     /gene="grpE"
                     /locus_tag="VW883_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0274480.1"
                     /translation="MAQDIKNEEVEEVEEVQEEEVVETAEETTPEKSKLDLANERADE
                     FENKYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDV
                     KKGLGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKG
                     YKLHDRILRPAMVVVYN"
     gene            complement(15150..16184)
                     /gene="hrcA"
                     /locus_tag="VW883_001348"
     CDS             complement(15150..16184)
                     /gene="hrcA"
                     /locus_tag="VW883_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0274481.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16348..16857)
                     /locus_tag="VW883_001349"
     CDS             complement(16348..16857)
                     /locus_tag="VW883_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0274482.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17464..19797
                     /locus_tag="VW883_001350"
     CDS             17464..19797
                     /locus_tag="VW883_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0274483.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19810..21273
                     /locus_tag="VW883_001351"
     CDS             19810..21273
                     /locus_tag="VW883_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0274484.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21273..22841
                     /locus_tag="VW883_001352"
     CDS             21273..22841
                     /locus_tag="VW883_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0274485.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            22898..23695
                     /gene="psrA"
                     /locus_tag="VW883_001353"
     CDS             22898..23695
                     /gene="psrA"
                     /locus_tag="VW883_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0274486.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            23706..24311
                     /locus_tag="VW883_001354"
     CDS             23706..24311
                     /locus_tag="VW883_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0274487.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(24259..>24770)
                     /locus_tag="VW883_001355"
     CDS             complement(24259..>24770)
                     /locus_tag="VW883_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0274488.1"
                     /translation="WRYIKFASLVNFRIGKTPPRSEATFWGTEIPWVSISDMPISGYV
                     TNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATHNEAIISIFPYANK
                     ENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNHEEMKRIISKVDLL
                     FQKVSQLFE"
BASE COUNT         7970 a         4844 c         4515 g         7441 t
ORIGIN      
        1 gcgataataa tactatattt aagaatcata atcttacaaa gaggacataa ttcctgaacc
       61 tacacaaata agtgttgctg ctcccccagt tatcggacca gtcgcagcag ctaatagtac
      121 tgctccaata caaccaccga ttgcagatcc taaattgcct cttcctccac taactatttc
      181 gagttcttca ttatccataa cagaaaattg ttccatcatt tttgtattca tgacaaatac
      241 tccttttttc tttttttatt tttgtcttgt tgtaactttg ataagtttag tatatcatcg
      301 ttttttaaaa tttttcatcc agatcttgaa ttgtcatcga aacgtcttga attagctttt
      361 ttattttaag ccacctctaa atgtttaaaa aaaataattt ctaatcactt ttttaccatt
      421 caggaagttt taatgactat tcaagatttc ataaaatatg aacttagttt tatgacataa
      481 tagacctatc cactatatga aaagaattgc caatgacttc ttataaacgt acatttgttc
      541 ctcaaataga tgcgagagac tgtggtgtcg ctgccttagc ctcgattgct aaattctatg
      601 gttcagattt ttctctagct cacttgagag aacttgcaaa gaccaataaa gaagggacga
      661 ctgctcttgg cattgtaaaa gccgctgatg aaatgggctt tgaaacaaga cctgttcaag
      721 cagataaaac gctctttgac atgagtgatg tcccctatcc atttatcgtt cacgttaaca
      781 aagaaggaaa actccaacat tactatgttg tctatcaaac aaagaaagac tatctgatta
      841 ttggtgatcc tgacccttct gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg
      901 aatggactgg agtagctatt tttctagcta ccaaacccag ctatcaaccc cataaagata
      961 aaaagaatgg tctactaagc aagcttcctt cctctgattt tcaaacaaaa atctctcatt
     1021 gcttacattg ttctctcaag cttattggtc actattatca atataggtgg ttcttactat
     1081 ctccaaggaa tcttggatga gtacattcca aatcagatga aatcaacttt aggaatcatc
     1141 tcagttggtc tggttatcac ctatatcctc caacaagtca tgagcttctc cagagattat
     1201 ctcctaaccg ttctgagcca gagattaagc attgatgtga ttttatccta tattcgccat
     1261 atttttgaac ttcccatgtc tttctttgcg acacgtcgta caggagaaat catttcacgg
     1321 ttcacagatg ctaactctat tatagatgcc ttggcttcta ccattctttc tctttttctg
     1381 gatgtttcta ttctgattct tgtaggaggc gtcttactgg cacaaaaccc taatctcttc
     1441 cttctttctc ttatttctat tcctatatac atgttcatca tcttttcttt tatgaaacct
     1501 tttgaaaaaa tgaaccatga tgtcatgcaa agtaattcta tggttagctc tgccattatc
     1561 gaagatatca acgggattga aactataaag tcgctcacga gtgaagaaaa tcgctatcaa
     1621 aatatagaca gcgaatttgt agattatttg gaaaaatcct ttaagctcag taaatattct
     1681 attttacaaa cgagtttaaa gcagggaaca aaattagttc tgaatatcct tatcctatgg
     1741 tttggcgctc aattaatcat gtcgagtaaa atttctatcg gtcagctgat tacctttaac
     1801 acactttttt cttactttac aactcctatg gaaaatatta tcaacctcca aaccaaactc
     1861 caatctgcga aggtcgctaa taaccgtttg aacgaagtct atctagtcga atctgaattt
     1921 caagttcaag aaaaccctgt tcattcacat tttttgatgg gcgatattga atttgatgac
     1981 ctttcttata agtatggttt tggacgagat accttaacag atattaatct cacgattaaa
     2041 caaggagata aggttagcct agttggagtt agtggttctg gtaaaacaac tttagccaaa
     2101 atgattgtca atttctttga accctacaaa gggcatattt ccatcaatta tcaggatatt
     2161 aaaaacattg ataaaaaagt cttgcgccgt catattaatt acctaccaca acaagcctat
     2221 atctttaatg gctctatttt ggaaaactta actttgggcg gtaatcatat gattagccaa
     2281 gaagatattc taagagcttg tgaattagct gaaattcgtc aagacattga aagaatgcct
     2341 atgggctatc aaactcagct ctctgatgga gctggtctat caggaggaca aaagcaacga
     2401 atagccctcg ctcgtgctct tttaactaaa tctcctgttt taatactaga cgaagctact
     2461 agcggtcttg atgtcttgac tgagaaaaag gttatagata atcttatgtc tctaactgat
     2521 aaaaccattc tctttgtagc ccatcgtctc agtatagccg aacgaaccaa ccgtgtcatt
     2581 gttcttgacc aggggaaaat cattgaagtt ggtagtcacc aagagttaat gcaggcgcaa
     2641 ggtttctacc atcatctatt caataaataa ggagaatgtc atgaatccta atctttttag
     2701 aagcgtcgag ttttatcaga gacgttacca taactatgcg acagtgttca ttatacctct
     2761 ttcattacta tttactttca tcttgatttt ctcccttgtt gccacaaaag aaattactgt
     2821 tacttcccaa ggagaaatcg cccctacaag tgtcattgcc tccattcagt caaccagtga
     2881 taatcctatc ctagctaatc atttagtggc aaatcaagta gttgaaaaag gggacttact
     2941 catcaaatac tctgaaacaa tggaagaaag tcagaaaact gccttagcaa ctcaattaca
     3001 aagacttgag aagcaaaaag aaggacttgg aattttgaaa caaagcttag aaaaagcgac
     3061 tgatcttttt tctggcgagg atgaatttgg ctaccataat acctttatga attttactaa
     3121 acaatcccat gatattgaac tgggtatcac aaagactaac accgaagttt caaatcaagc
     3181 taatctttcc aatagcagtt catcagctat tgaacaagaa attacaaaag ttcaacaaca
     3241 aattggagaa tatcaagagt tgagagatgc tatcataaat aacagagcac gcttaccaac
     3301 tggcaatccg caccagtcaa ttttgaatcg ttatcttgta gcctcacaag gacaaacaca
     3361 aggaactgca gaggagccat ttttatctca aattaatcaa agtattgcag gtcttgaatc
     3421 atctatcgca agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa cttatgataa
     3481 cagtttagca accaaaattg aagtactccg cactcagttt ttacagacag cctcacagca
     3541 acaactaact gtggagaatc aattaacaga attaaaagta caactagatc aagccacaca
     3601 gcgtttggaa aacaatacct taacctcccc aagtaaaggt atcgttcatc tgaacagcga
     3661 atttgaaggt aaaaatagaa ttccaactgg tacagaaatt gctcaaatat tccctgtcat
     3721 cacagataca agagaagtac taatcactta ctacgtatct tctgactatc tacctctact
     3781 agataaagga caaactgtaa gattaaaact ggagaagatt ggaaatcacg gcaccaccat
     3841 catcggccaa cttcagacaa ttgatcaaac tcctaccaga acagagcaag gaaatctctt
     3901 taaattaacc gctcttgcaa aactatctaa cgaggatagt aaactcatcc aatatggctt
     3961 acaaggtcgc gtcactagtg taactacaaa gaaaacatat tttgattatt tcaaagataa
     4021 aattttaacc cattctgatt aattttcaga taacactcta taactattta ttatcttatc
     4081 aaaaaggaga atcataacat ggataagaaa caaaacctaa cttcatttca agaactaaca
     4141 actaccgaac tcaaccaaat tacaggtgga ggattgtggg aagatttatt atataacatt
     4201 aatagatatg ctcattacat cacataagaa cttcatcatc caatacaact ataaaaaaat
     4261 aagaccgaga aacaagtact ctcggtctta tttttcatca ttctgtatgt atcacagtaa
     4321 gtacctgacg aaagacttga ttttgacagg tggtatttag actggtatta ggatggcttt
     4381 ccacaatctt catgacggta tagagaccaa ctcctctctc ctccccttta gaactggctc
     4441 caaaggagaa gatttcagaa atatcgatgc cctcttcttt gatggagttt tcgatgataa
     4501 aggtctcctg tgctccattt tttaaaaagg cgattgaaac atgaggttga ctagcttcca
     4561 cactggcttc aatagcattg tcacaaagga tagacacaat ggttagaaaa tcaagtagac
     4621 tcatcccctc gacctgaatc tcctcaggaa cttcgacatt aaagacaatg ttcttatctc
     4681 tggcttttaa aaatttccct gctagaagac ttttgagggc tttatcacga atatttacca
     4741 atctgcccag gtcatattta ttgttctgca atttctgact ggaatccttt aagacggagc
     4801 catagacctc ttttatctgc tccatatcct cctcttcaat gcccagacgt aagctagtca
     4861 agaggttggt ataatcatga cgaaagctcc gtacttcctt gtaaagctcc tctatatgcc
     4921 gactatagcg ttccatatct ctatagcgca gggcctgctc ttgttccaat ctctcataga
     4981 gtttttcctt caaataggta tccaatttct tgataacccc cataaaaaag agtaggtaaa
     5041 agactaggat gagatggcga acagtctttg attgaatact ttgttcatat tcaaaaaaag
     5101 acagactttc catgactaga tagtagccac ccattatcca gttaatctga gtcagggact
     5161 tttgaaaggc tttatcgaga atctcctttc tcaagctagt aaaatcgtag tccaaccatt
     5221 tcaaaaaagc tagagaaatg aagaaattga aaattattat acataaccca gtaaatgagt
     5281 agccatcata tacttgccct tgtcccaaaa atggaagcac aaaataggag actcctctat
     5341 aaaagagatt caccaatatc attggaaaga gaccataaaa gaaaaggagt tttttaggaa
     5401 gccctctcaa taataagaaa gataagccta tgccgtacaa gggttccata aaataagata
     5461 ggtaaacatt tcctaccata taaccaatca tcacaaaaac aaaggccaac agtatcttaa
     5521 aaagaaaggc cttaaaaatc ctctcgaaag taagatcaat tccatccacc ttaaagaaaa
     5581 tgacaatttc tagtccatta gtaacaagtg tatacaacaa tatccaagca atgttcataa
     5641 attctcctag ctcagtgtaa tttattgatg gcctcagaca cttccctgac cttataacgg
     5701 gcgattagac aacttccacc attgggaaag aaaagcagtt tttctttctt atccaaatgc
     5761 accacatttg caggattgat gagaaaagag cggtggcact gcaagagacg gggctcctgc
     5821 ttgaaaacct cctctaaact cgctgtaaat tccagcctgt ctgtcttggt atagagaata
     5881 acacgatggg ctctgggcga cgtttcgaga tagtaaacct ctttaaaagg atactgaaat
     5941 tgggcaaatt ttgatttaaa gtaaaagcaa tcttccgcca gacttttact atcttgacta
     6001 ttggcataga ggagggctgt ctcgatccga gattcaaact cctctgctga caaggcctta
     6061 tcaatgtagt ccaaagcaga cacttggtag cgaaaagaca ggggcataaa ctccgagtga
     6121 gtcgtcacaa agacaatcag ggcataagga tcccgatccc gaatctttct agccacttcc
     6181 agtcccttca tctcttcatt tcgaatctca atatccaaaa agaatagctg atgggccccc
     6241 ttctcatgca cttcagccag cagttggtcc ggcttgccaa atacctcaaa agagctagga
     6301 atgatatgat gtgctttcaa aagtttctca atcgtcgttt caattctagt ctgttgggaa
     6361 aaatcatcct ctaaaacaaa tattctcatc ttcttactct ccctctttca accatttttg
     6421 acgaatttct ctatagcgac gtctggcata cttgacagcg tattgacctt cttctccgag
     6481 aaaaaggatt ctttcttgaa aatcaatcga ttttaattta tcaagattaa ccaaacaatt
     6541 tcgatgacat ctcatcaagg tttccccaca ttggttctca agattactta aattttgaag
     6601 catattaaaa ctagcttctt ctgtaacaat ctgtacggta tgggctttag ttggatgtgt
     6661 ttggatatag tagatatcgt cgatgtttac tttatagact gttttctgcg tctgaataat
     6721 catatatttc attggattct cctcctaaga aaagaataac agaaaaggtc tagcccaagc
     6781 acacccaatc ctaaacagtc tttgaaaact cctaaaagga ttattttcta caacatcatg
     6841 atgagcttac aactatttta tcataaaatt cactcagcgc aattcaagac atttcaatga
     6901 caattaaaga tttgaataaa aaaaaagaat taaaagtgat aaactaacag tatcaaaaca
     6961 cagttgccag aagtaagact ggcacccaga ttaaaggagg cattcccatg acagatacag
     7021 accccatcaa aagagctcat actttgatta ctgacttaaa caaagcctac caagcatgca
     7081 aacaggcaag cgctgacgac gtccgctttc aggagcaatt aaactctatt cttggttttc
     7141 tagccaagac tgaaacagtg gataatcgat tcttgattga actagaaaaa ttttaccaga
     7201 cttccagtct tctcatggga ctcagcgctc ttgatccaga tgctccaact cgcgccgctt
     7261 ggcgggccta tgaccgcttc cactttgacc aagtcaagac caagttaata ctcaatgaga
     7321 atcaaagagc aaactaggaa gctagccgca agctgtactt gagtacggta aggcgacgct
     7381 gacgtggttt gaagagattt tcgaagagta taagtctcta cggaccaacc attatcctgt
     7441 agtaacaaaa aagaagctga gacaaactga actcaacttc ttttttagtg tcgtatcagc
     7501 aatgttagtc ctgcatctga cgttttacct gataaggcaa atacaagact agtaaaacca
     7561 aaccagctcc tagtaaggct agaagggcta gtttttcttg gaaggtaatc aacccaacaa
     7621 ctaattccac aagtaaaaca aaactggtca atcctcgaac tacctcctgt aagccttttt
     7681 ccttttgccc cttgtccagc ggaaagagtt gggtcaaata ctggtagtca aaggcatgat
     7741 agagggccag caactggaag agcaagaggt agttaaagag aactaccact gctgtcgcaa
     7801 tccaagcttg ctcgataaaa acctgcgcca gtacggaaag taagagaaga cgaagactga
     7861 gagcaaagag gtcgccattt cgcagataag aacgcagata gagattttgc caaatcttcc
     7921 caggcacctt ctgaacagcc tttaagataa agtccagata ggcacgacgc ttgacactgt
     7981 ttgaaattcc cttgacctgc gtaaagaggg caaagaaacg aagcaagact tgcttacgct
     8041 tgctttcttg agaaataaga tagtcccagt ccagtccagt ttcagtgaaa aatttgctgg
     8101 ccttttgacg aaagtggaaa tattttccta cccccaataa aagcacatag agcagaaaaa
     8161 ctggcaagcc ataacccatt gctaaaaaca agggcgcaaa taacagcaag aaaagggtct
     8221 gtacaaagag ccaaaagact agggaaatgc cagtttgacg cttgagatgg agcttgattt
     8281 cctcttctcc aactaagaga aagagcttgt ctggagcctc catataggtg gcaattcctc
     8341 cccaaagtaa aagtaaaaca gacgtaattc ctacaaacaa aagaataggc caatgatttt
     8401 caggaaaatg ttgtaagagt tgactgtact ggtaggctag aaagcccaac aggacaagca
     8461 ggaataagac aaagtggtca ttgagcacat agcgcagata accaagacac tccttacgaa
     8521 aggcctgctt tctctttaaa aacaagtctt tcataggtcc tcctcttttg tcagagccaa
     8581 gtaaatatca ttcaaactag cctcaggcat atcaaaggct tcgcgtagtt gcaggagatt
     8641 gcctttggca cgcacctctc ccttgtgaag aatgacaaag gcatcacaca tcttttccgc
     8701 cgaatccagc acgtgggtac tcatgagaat agacttgccc ttttgcttct ccacttccaa
     8761 aagctgaatc aaatcagaaa tagccagcgg atcaagacca aggaaaggct catccacgat
     8821 gaaaagactt ggatccacca caaaagcaca gataatcatg accttctgct tcatcccttt
     8881 tgaaaaatga acagggaacc agtctaattt ctgttccaga cggaacatct ttaacaaggg
     8941 ctctactcgt tcgaaagcca ctttttgctc aataccataa gccatagcaa ccgtttcgat
     9001 atgctctctg agggtcaatt cctcatacag actaggcgtc tcaggaatgt agccaatctg
     9061 cttgcggtag ctagtcgcat ctccttgcag agtcaggcca ttgatattga tggagccact
     9121 ataaggtgcc aacagaccga taatctcatt gatcgtcgtt gatttcccag caccattgag
     9181 accaatcaaa ccgaccaact gcccactttc aacagtaaag gacacatctt tcaaaacagg
     9241 aacatgaaca tagccacctg tcaggttttt aatttctaac atattttctc caaatctggt
     9301 ataatgtagc tatattatat caaaattcag tacagtagag gtagatttta tgtcagattg
     9361 cattttttgt aaaatcatcg caggggaaat tcctgcttca aaagtatatg aagatgagca
     9421 ggtccttgcc tttcttgata tctctcaagt aacactagga cacaccttgg tcgtgccaaa
     9481 agaacactat cgcaatcttt tggagatgaa tgctacgagc gccagccaac tctttgccca
     9541 agtaccaaaa gtagctcaaa aagtcatgaa agtcactaag gctgctggta tgaatatcat
     9601 ttccaactgt gaagaagtcg ctggtcaaac agtttttcat actcacgttc accttgtgcc
     9661 tcgctacagt gctgacgatg acctcaagat tgattttatc gcccacgaac cagactttga
     9721 caaacttgct caagtcgctg aaaccatcaa aaacgcttaa ggagttgcta tgaaattatc
     9781 caacctactg ctatttgcag gagctgcagc cggaagttat ctggttacaa aaaatcgcca
     9841 aaccatcaca gatgaagtct taaataccac tgaccgcgtt caagctatca aagacgatgt
     9901 ggatattatc caaaatagcc tgcaaatcat cgaccagcaa aaagaactta tcaaggaata
     9961 ccaagaagac ttgacttaca agtttaaggt cttggaaaag gatatccaga ctagactagc
    10021 tgtgataaaa gaaatgcagg gaactgaaga taagtaaaaa gagcccccgg ctctttttta
    10081 aaacgtaaac aagttatagt gaattgaatt tagaatagca caccatagtt tctaaagcat
    10141 tgttagagat tactttaaaa tcctcttatc aatttgttca tattctattt caatctatta
    10201 tatatatccc atcaactatg catcataatt taggtaactc atactcaata aaaatcaaaa
    10261 agcaaactag aaagctaggc acagactgct caaaacaccg ttttaaggtt gtggatagaa
    10321 ctgacgaagt cagtaaccat acccatgata agccgacgct gacgtggttt gaagaaattt
    10381 ttgaagagta tcattctcca tcaaaggcat cttttatatg gtcaaagaag ccttttttct
    10441 ttggatttac tttcaagtca ccagcagccg cgaattcttt caaggctact ttttggcggt
    10501 cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc
    10561 cacgaaggct cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct
    10621 ctggaataac caattcaaca tcaccgtgaa cagttggaat atctactgta tcaccaagag
    10681 ccgcttggac aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact
    10741 tgtcgctagc ttctacagaa actactacat acaagtcacc ataaggtcca ccgttaaagc
    10801 ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt
    10861 tcacatgtac gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat
    10921 atttgatttc ttttccttgg ccgtgacaga catcacaggt tacttggcga cgcatcatac
    10981 caagaggagt ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga
    11041 ctggacttgt ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat
    11101 gatacttaac ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat
    11161 actggagatc atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga
    11221 agaaacttga gaaaatatcc tcaaaaccac cgaagccacc tgccccattg aaaccgccga
    11281 aaccaccagc tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataagcag
    11341 cacgtttttg gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct
    11401 cagcaccagg ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct
    11461 ttttgatttc gtctgccgaa gcgtttttgg atacccccag acgatcataa aattcagtat
    11521 tgttcataat tcaagataca aagggcgtca aacggacaca gccatctagg agttttgacg
    11581 acggacgctt atgtcctaga aaaaactatc tttttggcac agtccgtagc ccgtgttcag
    11641 ttacgaacac ccttattcct ttctattgat gttctgaatc gaaccaccat ttaggtcggg
    11701 ttcaattcct ttcttttata tttagtaaga aattctgaaa cccgtgttca gttacgaaca
    11761 ctctttgttc ctttctattg atgagacaaa acccaaacaa atgagattcc gtcccttttt
    11821 atcgaaaaac agaggctggg ttgcaacctc tgcaaataag taaattaact ttattttgat
    11881 tttaaatatc ctataagtac agaaatattt atatattttt gtctcttctt agtatttgcc
    11941 tatataattc caattgatca taagaaatac aactactgtc caaatcatac caattatgaa
    12001 cggtattaca aatttatatg tttgtatttc taatgatatc atagctgata ccatcgccga
    12061 tacaaatgca gacaacaata ctgaggtaac aaaattcctt accgcttcat catttttgat
    12121 acaactatca tgttcagcta atataatttc tctatatcta gtcaaacatt ctactggaat
    12181 attatctata aaaccttttg ctgcttcata gttgtcagct tgattacaaa aatcattata
    12241 aacttttcgt gtatttttta gatactcatc atccaataca ctcatcttac ttttccgtaa
    12301 actctccgtc tacgacgtca tcgcctgcgt ttcctgttgc ttgtgcgcct tctgctcctt
    12361 cttgagcttg ttgcgctgct gcggcttgtt cgtagagttt aacagcaagt ccttgagctt
    12421 tttcgttcaa tgcttcaagt ttcgctttca tgtcgtccaa gttgttgtct tcttgagctt
    12481 tcttaaggtc atcaagggca gcttgggcag cgtcacgttc tgcgtcgaag cctttacctt
    12541 cagtttcctt gattgtcttt tcagtcgcaa agattgcttg gtctacttca ttacgaaggt
    12601 ctacttcttc tttacgtttc ttatcggctt cagcgtttgc ttctgcatct ttcatcatgc
    12661 ggtcgatttc ttcgtcagtc aaacctgagt tcgattggat gacaatagtt tgttcttttt
    12721 gagttccaag gtctttggcc ttaacagaca cgataccgtt cttgtcgatg tcaaatgtta
    12781 cttcgatttg aggaattcca cgaggtgcag ctgggatatc agtcaattgg aagcgtccaa
    12841 gagtcttgtt atctgctgcc attgggcgtt caccttgaag aacgtggata tcaacggctg
    12901 gttggttgtc tgctgctgtt gagaagactt gtgatttaga tgttgggatt gtagtgttgc
    12961 gatcgataag ttttgtaaat actccaccca ttgtttcgat accaagtgac aatggcgtta
    13021 catcaagaag gacaacgtcc ttgacatcac cagtaatcac accaccttgg atagccgcac
    13081 ccatagcaac tacttcatca gggtttactg atttgtttgg ttctttacca gtttcagctt
    13141 taacagcttc aacaacggca gggatacgag ttgaaccacc aacaaggata acttcgtcga
    13201 tttctgacaa gctcaaacct gcatctgaaa gggcttgacg aactggaact tttgtacgtt
    13261 caacaaggtc acgagtcaaa tcatcaaatt tcgcacgagt caaagtcatt tccaagtgaa
    13321 gaggtccagc ctcacctgca gtgataaatg gcaagctgat ttgtgttgaa gttacaccag
    13381 aaaggtcttt cttcgctttt tcagccgcat ctttcaaacg ttgcattgcc atcttgtcag
    13441 tagacaagtc gataccgttt tctttcttga attctgctac caagtggtca atgatttttt
    13501 ggtcaaagtc gtcaccacca agtttgttgt cccctgcagt tgacaatacg tcgaagacac
    13561 cgtcacccaa ttcaaggata gagacgtcga atgtaccacc accaaggtca aataccaaga
    13621 ttttttcttc tttatcagtc ttgtccaaac cataagcaag agctgctgca gttggttcgt
    13681 taacaatacg ttctacttca agaccagcaa ttttaccagc gtcttttgtt gcttgacgtt
    13741 gagcgtcgtt gaagtaagcc ggaactgtga taacagcttt ggttactttc tcaccaaggt
    13801 agtcttcagc gtagcctttc aagtattgaa ggatcatagc tgagatttct tgtggagtgt
    13861 attcttttcc atttgcagaa actttttcag aagttcccat cttagatttg atagagataa
    13921 ctgtatctgg gtttgtgact gcttgacgtt ttgcagcatc accaacgatg atttctccgt
    13981 ttttgaatga gactacagat ggagttgtgc ggtttccttc tgggtttgcg atgattttgc
    14041 tttcagttcc ttcaagaact gcaactgctg agtttgttgt acctaagtca ataccgataa
    14101 ttttagacat gtgtttttct ccttgttagt taattttcta tttttctttt tgatactctt
    14161 cttaagtggc gacgccgtca gagcttgact tcgtcaatct ctttgactaa actttgagcc
    14221 taaggtctca aaatttgcgc aaatagcgcc acggcgaaga gtatcgtgtt tggttcgctt
    14281 cgctcactat tacaaagcca aacatatttt atctttcttc atagtttatt gtcgtttcgg
    14341 acaagttttc tattatgtaa attgcgacac gaagagtcga aatcgatttt atttcgacga
    14401 cgagttagta aggaagctag gcaaacgcca tagcgattgc cgttttctga cgagttgctt
    14461 tagctaccgt cagaattgcc gaatcgaaca cgccctaagc tctgagtaaa aaagatagat
    14521 tttcttgtgt tcatcgaaca cttcgttaat ctcctatttt tactgcgagc tttttacggg
    14581 ctttgtatct tagttataca ccactaccat tgctgggcgt aggatgcggt catggagttt
    14641 gtagcctttt tgaaagactt gagcgatggt atctactggg tgttcatcgt ctgctgggag
    14701 agtttgtatg gccatatggt agttatggtc aaattcgcca tctgctgcga tttcttcaat
    14761 tccttcttct ttcaaagcgt gaatcaagct ttcttgcacc atccccaagc ccttcttcac
    14821 atcatctgtc aaaccttcaa ctgcaagtgc acgctcaagg ttgtcaagag atggtaagat
    14881 tgcttttgcc aagtcctggc tacgataacg ttgcaagttt tgacgttctt cattggcacg
    14941 gcgttggata ttttgcattt ctgcatgagc gcgaagatat ttgttttcga actcatctgc
    15001 acgttcattt gccaagtcca acttagactt ttcaggagtt gtttcttcag ctgtttccac
    15061 aacttcctct tcttgaactt cttctacttc ttctacttct tcatttttta tatcttgggc
    15121 catgttcgcc tcctttaatg atttcaatct taatgtactt cgtaatgatt actgctgagg
    15181 tagcggtaaa aatctgtcaa cttcatagtc aaaacacggt tgaccacatt gacttgattg
    15241 attagctgtt ggtaatccag attaactgga ccgataatgg ctagaattcc aactcctcga
    15301 taaggaatga ggaacttact actaatcacc gctaggtcag ctaaacagga ctcttgaccg
    15361 tctgcaatac gaacattttg catctgatcc tcacgcaacc cctcacgaat ctccaaggcc
    15421 accttttgcg gttggtcaaa gaactgatag gctgctagat tggcaaaatt caagagattg
    15481 accttgcccg ccatcacaat gttttcgttg aacatttcct taaagatgtg ttcaaagaga
    15541 tcgatgacat tatccgttgt tgtaaagtaa cgctggataa tctgcggaat ctccgtccga
    15601 atcttgtagt gaatatctaa aacggtgtga ccgaggaaac gttcctgaat gatgctcttc
    15661 agtttcagca aatcctcctg caagaagttc cttggaatca gaaactgact agtaaccgtt
    15721 cgcgactcgt ctagggtaaa taccgccaag gctgtatgtt gccccaaaac aacgatatca
    15781 aaggctgtca aacgttgcct gctcggctca acatccagtg ccactaccgt acagccactc
    15841 aggtctgtta gcaagttagc agcctcttgc agaatatcct ccaatttgaa gaattcctga
    15901 tcaaaggctt tgacaatctc atatacctca ttttcagcca gccggtgaaa atccagtgag
    15961 tgtttcacat agtactgaaa accagcaaca cttggcatcc gaccgcttga agtatgagcc
    16021 ttctcaagca acccttgttt ttctagttcc gccatgtcat tacgaatggt tgcactgcta
    16081 gagttaatag actcttgcaa ggcttttgat ccgacaggtt cgtgcgtttt ggtaaagatg
    16141 tcaataatca gatttaaaat atcctgctga cgctctgtaa ccatctcatc actcctctct
    16201 gtctgatcaa ttagcactca atgcatccaa gtgctaactt atgattctat tatacaccct
    16261 tagaagagaa tgtcaagaca aaaactcaaa aaattagcac tcttttatca agagtgctaa
    16321 aaatcaatct gaagacctag aaccttgcta ttcatctact cggtatttcc tttttagtct
    16381 gaaataacca tgaattagat aagaaatcag aaaagcatat aaaacaaaaa taagaaagaa
    16441 agacatagaa agatcctctc taaacaaact cgtacaaaca acaagaccac ctaagaaagt
    16501 agttgtacag gaacgaagtc tagatcgcat aacttcccat ttgagcccct tactcatata
    16561 gacttgatcc tctggaagta aatcagaaga cgatttacga agaatcgaac aagaacctgc
    16621 tcctatcaat tcccaacctc tatctctaaa atcttgcagt tcatgcttat attttttaag
    16681 aaatctagaa tcatagatac ggtagatgac atcgtctggt tgacattggt caaaatagaa
    16741 caaaccaaaa cgactcgttc tatacctcca acctttcaaa tgcatctcat gtaaatattc
    16801 ttcttccttg tccaaatcaa caatagtgaa aatccgaaat tctactctgc tattcattgt
    16861 cttaccccaa aattagaaaa catgcctggc gttatttatt agataattct ttccgctttt
    16921 gactcaatct ccaaaaaata taagaaatct gaatcgcaaa aactatcaat aaaacccaat
    16981 ctattatgaa agtcaaaaac acttcccaac tgaaagaact acctccagtg acaaactttg
    17041 agaaaaacgg tagtagagct aaaaagagaa gcaaaatagg aagcatccgc attgttaaaa
    17101 tccttttggc ataaaaaaat ctttatttaa acgaaaatat tatggcaaaa tttacgccag
    17161 tttttgaacg gctgatgtag atattttata ctttcaaaat gtttaaatgt gattatttat
    17221 ttttgaaaaa tagctcacca gcccgactga aagtgcttat aaatgataat aagtcgcctg
    17281 ccgaaaacag cgaaaaatag cggtgttatg cggagataat ctgacgcgat gcgaaagtat
    17341 attgcatact tattttcaac aatttagcag agtattttta taagtgtgat ataatagaag
    17401 tataatttgt tctgatagtt tattttatgg agaagtagat ttttagaatg cggagggttc
    17461 aatatggttg agtttataaa gtctaagaaa gaaatgagtg aggaggatat taaagcaaat
    17521 ttcatcactc ctgctattgt atccaaagga tggaaaaatg gtgagcatat cgcttacgaa
    17581 gaatacttca ctgatggtcg aattgaggtt agaggagata aggctcgtcg taaagaagga
    17641 aaaaaatcag actattcact gtattaccaa tttggaactc gaattgcaat tgttgaggca
    17701 aaggataata aacacagcgt tcgagcagga ttacaacaag ctattgaata tggagagatt
    17761 ttagatgttc catttgttta ttcttcgaat ggtgatggct ttattgaaca cgaccgtatc
    17821 acgagagaag aacgtgagct ggagttagat gaattcccta ctcgtgaaga attattttct
    17881 cgtatgacga aggaaaaagg attgacgtac gaaattacag aagctatctc aactccatac
    17941 tatacagacg ccttctcaat gaaaacgcca cgctattatc agcaaatagc tatcaaccgt
    18001 actattgaaa cagttgccag aggacaaaaa cgagtaatgt ttgtgatggc aacaggaacg
    18061 gggaaaacgt tcatggcttt tcaaattatt catcgccttc gaaaagctgg tttggctaaa
    18121 cgagttttat tcttagcgga tagaaacatc ttagtagacc aaacgatggc tgaagacttt
    18181 aggccattcg aaaaggtaat gacgaaaatt acaccaaaac ttttgactgc tcctgaaaaa
    18241 ttaaattctt ttgaaattta tctagggctt tatcagcaac taactggtga agatggaact
    18301 gaaacacatt atcaaaaatt tgacaaagac ttctttgatt taatcgtaat tgatgaagcg
    18361 caccgtggtt cagctaagga aaacagtaac tggcgtaaga taattgatta tttcagttct
    18421 gcgacacaga ttgggatgac cgctactcct aaagaaacca agaatgcttc caatacggaa
    18481 tactttggtg agccaatcta tacttatagt ttaaaacagg gaatcgagga tggttttttg
    18541 gctccatatc gtgttatgag agttaattta gatgtagatg tggatggtta tcgtccagaa
    18601 actggaaaag ttgatgctaa cggacaatta atagaagata ggtactacgg caggaaagat
    18661 tttgataaaa ccattgtcat tgatgataga acgcaaagag ttgccaagtt tgtttctgat
    18721 tatatgaagc aaaacaatgc acgatttgat aaaacaattg ttttttgtgt tgatattgac
    18781 catgccgagc gaatgcgtgc tgcacttgta aaagagaatc tagacttagt ccaagaagac
    18841 tatcgttatg tcatgcaagt aactggtgac aacgctgaag gaaaagctca actggataac
    18901 tttatggatg tcaattctaa ttttcccgct attgtaacaa cgtctaaatt attaacgaca
    18961 ggagttaatg ctaaaacatg tcgtttgatt gttttagact ctaatatcca atccatgact
    19021 gaatttaaac aaattattgg tcgtggcaca cgtctttatc ctcaaaaggg gaaagaattt
    19081 tttacgatta ttgattttcg aaatgttacc aatttgtttg ctgaccctga ttttgatggt
    19141 gatccagtga aggtgctgga aacaggtgcg aaaacagtca gtggttctac gcccggtttc
    19201 gtaagtgagg aaggtgaccc agtagaaaaa tatatcgtta cagacaagca ggttaccatt
    19261 cttaattcta ctgttcaagt attggatgaa aacgggaaac tgattaccga aagcctgacc
    19321 gactacactc ggaagaatat cttaggtagc tacgccactt tgaacgattt tatcacagtt
    19381 tggcatacgg cggataaaaa gaagcttatc ttagacgaac tttataaaaa aggagtttat
    19441 ctagatgcta ttcgagagtc ggagggaata tcagaacaag aaatcgatga ttttgattta
    19501 ctcctaaaac ttgcctatgg tcaaaaagaa ttaaccaaaa cggaacgtat caataagctc
    19561 aaacaaagcg gatatttata taaatatagt gaggaagcgc gtgctgtttt ggaaatttta
    19621 ctgaacaaat acatggataa aggtattgga gaactcgaaa gcattgaaac attaaaactt
    19681 ccagaatttc agatatatgg tggaaccttc aaaatcatca atacttattt tggagataaa
    19741 aaacgatatt tacaagcaat taaagaattg gagcaagagc tatttacagt agcttaatga
    19801 aaggaaagta tgtcaattac atcatttgta aaaagaattc aagatatcac tcgaaacgat
    19861 gctggtgtta atggtgatgc tcaacgtatt gagcaaatgt cttggttatt attcttaaaa
    19921 atttatgata gccgtgaaat ggtttgggaa ttagaagaag acgagtatga gtcaattatc
    19981 ccagaggaat taaaatggcg aaattgggct catgctcaaa atggggaacg ggtattgaca
    20041 ggcgatgaat tacttgattt tgtcaataac aagttattca aagagttgaa agagcttgaa
    20101 ataacttcaa atatgcctat tcgaaaaacg attgttaaat cagcttttga agatgcgaac
    20161 aactatatga aaaatggcgt cttgttacgc caagtcatca atgttattga tgaagttgat
    20221 ttcaatagcc ctgaagatcg tcattcgttt aatgatattt acgaaaaaat tcttaaagat
    20281 attcaaaatg ctgggaactc aggagaattt tatacgccac gtgcagcgac tgattttatt
    20341 gccgaagttc ttgacccaaa acttggagaa tcaatggcag accttgcttg cggaacagga
    20401 ggcttcttga cttcgactct gaaccgttta agtagtcaac gtaaaactag tgaagatacc
    20461 aaaaaatata atacagctgt ttttggtatt gaaaagaaag catttcctca tcttttagca
    20521 gttacaaatc tgtttcttca cgaaattgat gaccctaaaa ttgttcatgg aaatactttg
    20581 gagaaaaatg ttcgtgaata tacggatgat gaaaaatttg acattattat gatgaatcca
    20641 ccttttggag ggtcagaatt agaaacaata aaaaataact ttccagcaga attacggagt
    20701 tctgaaacag ctgatttatt tatggctgtc attatgtatc gtttgaaaga aaatggtcgt
    20761 gttggagtta ttttacctga tggttttcta tttggtgaag gtgtaaaaac tcgcttgaaa
    20821 caaaaactgg tagatgagtt caacttacat acgattatta ggttgcctca tagtgtcttt
    20881 gcaccgtata caggaatcca tacgaacatt cttttctttg ataaaacaaa gaaaacagaa
    20941 gaaacttggt tttatcgttt agatatgcca gatggttata aaaatttctc gaaaactaag
    21001 ccgatgaagt cagaacactt caatcctgtt cgtgactggt gggaaaatcg tgaagagatt
    21061 ttggaaggta agttctacaa atctaaatca tttacaccta gtgaattggc tgagttgaat
    21121 tataatttag accagtgtgg ctttccaaaa gaggaagagg aaatcttaaa tccctttgag
    21181 ttgattcaga attatcaagc ggaaagagca actttaaatc ataagattga taatgtatta
    21241 gctgatattt tgcagttgtt ggaggacaaa taatgacacc agaacaactt aaagcaagta
    21301 ttctccaaag agcgatggaa gggaaattag tgccgcaaaa tcccaatgac gaacctgcaa
    21361 gtgaattatt aaagagaatt aaagctgaaa aagaaaaact tatcagtgaa ggaaaaatca
    21421 aacgagataa aaaggaaact gagatatttc gtggtgatga tgggaaacat tatgggaagt
    21481 ttgctgatgg aagcactcaa gaaattgatg ttccttatga tattcctgat acttgggagt
    21541 gggtgaggtt ttctacattg gttgaaattg tcagaggtgg ctctccacga ccaatcaaag
    21601 attatcttac ttctgaagta gatggaataa attggataaa aataggtgat actgaaaagg
    21661 gtgaaaagta tataaataat gttaaagaaa aaatcaaaaa atcagggctt aacaaaacta
    21721 gatttgtaaa aaaaggtaca tttttgttaa ctaattctat gagttttggt agaccttata
    21781 ttttgaatgt tgatggtgca atacacgatg gatggttggc tatttcgaac tatgaaaact
    21841 cattaaataa agattaccta ttctatattc tttcatcaaa tgtagtttat tctcaatttc
    21901 tatctctaat tagtggagct gttgtgaaaa acttgaatag tgataaagtt gcttctattc
    21961 ttatccctct ccccccacta tccgaacaac aacgcataat agaagcaatc gaatcagctt
    22021 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
    22081 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
    22141 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
    22201 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
    22261 gagatgataa ctcttattat gaggaagtac cttgtgaaat accagaaagt tgggaatggg
    22321 tgaggttaaa cgatataacc tcctacattc aaagagggaa gtctccaaaa tattcaaata
    22381 ttcctatata ccctgtgatt gctcagaaat gtaatcaatg gtctggcttt tctattgact
    22441 tagcaagatt tattgatccc gaaacagttc atagttacca gaaagaaaga ttactaagag
    22501 atggtgattt aatgtggaat tcaacaggtc taggtacgtt aggacgatta gctatttacc
    22561 atgaaaataa aaatccttat ggctgggctg ttgcagatag ccatgttaca gttataagag
    22621 tcttatcggg agttattaat tgccatttca tctataattt tctttcctct cctattgttc
    22681 agtcagttat tgaagaaaaa gcgtcgggta gtacaaaaca aaaagaatta ttaacgaaaa
    22741 ctataaaaga atatttaatc cccctcccac cccttcctga acaatccaga atcgttgata
    22801 aaatcgaaca atttttcgcc catattgacg cactaattta gtataatagt tttacgtgcg
    22861 gtggaatttc tatcaaacat aagataggag ttttacgttg aaagattttg aattacattt
    22921 gaagaaagct ggtttagctg aaaatactgt gcgttcgtac ctttatggtg ttcgattttt
    22981 cttggagaat tacgaactca aaatggaaga tttatttgaa tacaaaggat atttattaga
    23041 caattttaaa cctaaaactg tcaatttgcg actacaagga gtaaataaat atctggcttt
    23101 tattggtcat gatgatttga aattaaaatt tgtcaaagta cagcaaaaac cgtttttaga
    23161 agatgtcatt agccatgctg attacctttt tcttaaacgt agtttgaaaa aagatggtat
    23221 tttaaaatgg cattttgtcg tttggttttt aggtgcaact ggggctcgtg taagtgaact
    23281 tattaaacta aaagtagagc atgtagaaat cggttatttt gacatttact caaaaggtgg
    23341 taaaattcgt agactgtaca ttcctaaaaa attaagaaat agttgtctta gttggttaga
    23401 atcagaaaat cgccgaagtg gttatttatt tttgaataaa tttaacgaac caattacagc
    23461 aagaggagtt gctcaacagt taaaaaatta tgctgataaa tacaaaatga atcctaaagt
    23521 aatttaccct cattctttta ggcatttatt tgctaagaat tttttagcga agtataatga
    23581 tattgccttg cttgcagatt tgatgggaca cgaaagtata gaaactactc gaatttatct
    23641 aaggaaaaca gctactgaac aacaaaatat tgtagataaa attgttaatt ggtaaaaaat
    23701 aacaggtggt caaactgact acctgctatt tttgtgatta tggctcttat tatgggaata
    23761 tacctatgaa ttgggttgtt ataaaaataa aagatatttt ttcaatgaat acaggtcttt
    23821 cttacaagaa gggcgattta agcattaata ataaaggtgt tagaattata cgtggtggta
    23881 atattaagcc tttagaattt tctctgttgg ataacgatta ctacattgat acacaattca
    23941 tctcctctga acaagtttat ttaaaacata atcagctaat aacacctgta tcaacctctt
    24001 tagaacatat tggaaagttt gcaagaatcg ataaagacta tgatggtgtt gtggctggtg
    24061 gatttatttt ccaattaaca ccattcgaaa gttcagagat tatttcaaaa tttctattat
    24121 ttaacttgtc ttctccgtta ttttataaac aattgaaagc aataactaaa ctatcaggtc
    24181 aagctttata taatattcct aaaactacac tgagcgagct attaattccg ttagctcctt
    24241 ttgaggaaca ggaacttatt actcaaaaag ttgagaaact ttttgaaaaa gtaaatcaac
    24301 tttggaaatg attcttttca tctcttcatg attagaaata gggattaata attcggagat
    24361 actggtacta tttaatgttt tccctttgat agcatctttt gaatcaccta aagtagagat
    24421 aagtggcaaa aatatcatta agtaatctct gataatattt tctttattag cataggggaa
    24481 tatcgatata atggcttcat tatgagtggc aggaatatcc aatatggcaa cttttccaat
    24541 agataactta aaactcatta ataaagttcc tttaggtgaa atgtctattt tctttgattt
    24601 taatgctaat ttagaaatag attctctcgt attagttaca taaccagata taggcatatc
    24661 tgatatagat acccaaggta tttcagttcc ccaaaaagta gcttcactgc gtggaggagt
    24721 ttttcctatt ctgaagttaa ctaggctagc aaatttaata tatctccatg
//
LOCUS       DAVKXA010000032        24768 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKXA010000032 DAVKXA010000000
VERSION     DAVKXA010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.032"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..512)
                     /locus_tag="VW883_001356"
     CDS             complement(<1..512)
                     /locus_tag="VW883_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274489.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSRMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFKHDFSCLPEIMSWDVET
                     VRGVTVSIGR"
     gene            complement(678..998)
                     /locus_tag="VW883_001357"
     CDS             complement(678..998)
                     /locus_tag="VW883_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0274490.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            1756..1824
                     /locus_tag="VW883_001358"
                     /pseudo
     CDS             1756..1824
                     /locus_tag="VW883_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0227 family bacteriocin-like peptide"
     gene            2137..2349
                     /locus_tag="VW883_001359"
     CDS             2137..2349
                     /locus_tag="VW883_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274491.1"
                     /translation="MLVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            2828..3073
                     /locus_tag="VW883_001360"
     CDS             2828..3073
                     /locus_tag="VW883_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274492.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            3230..4288
                     /locus_tag="VW883_001361"
     CDS             3230..4288
                     /locus_tag="VW883_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274493.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            4602..5579
                     /locus_tag="VW883_001362"
     CDS             4602..5579
                     /locus_tag="VW883_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274494.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            complement(6126..6284)
                     /locus_tag="VW883_001363"
     CDS             complement(6126..6284)
                     /locus_tag="VW883_001363"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274495.1"
                     /translation="MAQIVVIASPIDIQAANPLIADSANPATLFATRTPTYLAAAPAI
                     ALVTRRKP"
     gene            6538..7440
                     /locus_tag="VW883_001364"
     CDS             6538..7440
                     /locus_tag="VW883_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274496.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLQLNLEIPFDFVVSTSL
                     TFFVLILSKIVLDILYALKDLYKKEALITIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            7496..7849
                     /locus_tag="VW883_001365"
     CDS             7496..7849
                     /locus_tag="VW883_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0274497.1"
                     /translation="MELVLPNNYVVIDEEEMMYFDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            7846..8574
                     /locus_tag="VW883_001366"
     CDS             7846..8574
                     /locus_tag="VW883_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274498.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            9713..9952
                     /locus_tag="VW883_001367"
     CDS             9713..9952
                     /locus_tag="VW883_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274499.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            9937..10215
                     /locus_tag="VW883_001368"
     CDS             9937..10215
                     /locus_tag="VW883_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274500.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVILHFTSAKKYAKVRKTDVKEMKWL"
     gene            10501..12303
                     /gene="pspA"
                     /locus_tag="VW883_001369"
     CDS             10501..12303
                     /gene="pspA"
                     /locus_tag="VW883_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV0274501.1"
                     /translation="MNKKKMILTSLASVAILGAGFVESQPTVVRAEEAPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEEKAALEKAASEEMDKAV
                     AAVQQAYLAYQQATDKAAKDAADKMIDEAKKREEEAKTKFNTVRAMVVPEPEQLAETK
                     KKSEEAKQKAPELTKKLEEAKAKLEEAEKKATEAKQKVDAEKYALEAKIAELEYEVQR
                     LEKEIKEIDESDSEDYLKEGLRAPLQSELDTKKAKLSKLEELSDKIDELDAEIAKLEK
                     DVEDFKNSDGEQAEQYLVAAEKDLDAKKTELEKTEADLKKVANEPETPAPAPKPETPA
                     PAPEAPAPAPEAPAPAPEAPAPAPAPKPEQPAPAPKPEKSADQQAEEDYARRSEEEYN
                     RLTQQQPPKAEKPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGS
                     WYYLNANGSMATGWVKDGDTWYYLEASGVMKASQWFKVSDKWYYVNSNGAMATGWLQY
                     NGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQW
                     FKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            12704..13825
                     /gene="mnmA"
                     /locus_tag="VW883_001370"
     CDS             12704..13825
                     /gene="mnmA"
                     /locus_tag="VW883_001370"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0274502.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            13966..14421
                     /locus_tag="VW883_001371"
     CDS             13966..14421
                     /locus_tag="VW883_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0274503.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVREELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKSQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            14431..16344
                     /gene="mnmG"
                     /locus_tag="VW883_001372"
     CDS             14431..16344
                     /gene="mnmG"
                     /locus_tag="VW883_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0274504.1"
                     /translation="MIYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKAVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(16539..18218)
                     /locus_tag="VW883_001373"
     CDS             complement(16539..18218)
                     /locus_tag="VW883_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0274505.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(18220..18453)
                     /locus_tag="VW883_001374"
     CDS             complement(18220..18453)
                     /locus_tag="VW883_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0274506.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(19271..19423)
                     /gene="cibB"
                     /locus_tag="VW883_001375"
     CDS             complement(19271..19423)
                     /gene="cibB"
                     /locus_tag="VW883_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0274507.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYAIGKDLRK
                     KFGKSC"
     gene            complement(19425..19610)
                     /gene="cibA"
                     /locus_tag="VW883_001376"
     CDS             complement(19425..19610)
                     /gene="cibA"
                     /locus_tag="VW883_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0274508.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            19788..20471
                     /gene="tsaB"
                     /locus_tag="VW883_001377"
     CDS             19788..20471
                     /gene="tsaB"
                     /locus_tag="VW883_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0274509.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEYLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            20468..20905
                     /gene="rimI"
                     /locus_tag="VW883_001378"
     CDS             20468..20905
                     /gene="rimI"
                     /locus_tag="VW883_001378"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0274510.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            20895..21905
                     /gene="tsaD"
                     /locus_tag="VW883_001379"
     CDS             20895..21905
                     /gene="tsaD"
                     /locus_tag="VW883_001379"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0274511.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(21945..23251)
                     /locus_tag="VW883_001380"
                     /pseudo
     CDS             complement(21945..23251)
                     /locus_tag="VW883_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(23584..23878)
                     /locus_tag="VW883_001381"
                     /pseudo
     CDS             complement(23584..23878)
                     /locus_tag="VW883_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23985..24278)
                     /locus_tag="VW883_001382"
                     /pseudo
     CDS             complement(23985..24278)
                     /locus_tag="VW883_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            24546..>24768
                     /locus_tag="VW883_001383"
     CDS             24546..>24768
                     /locus_tag="VW883_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV0274512.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDY"
BASE COUNT         7672 a         4172 c         5234 g         7690 t
ORIGIN      
        1 catctcccga ttgaaacagt cactcctcgg actgtttcaa cgtcccagga cataatctca
       61 ggaagacaag aaaaatcatg tttaaagtga aaatcattga gctttcgaat gacagttgaa
      121 gttgaaatgg ccagctgatg agcaatatcg gtcatagaaa tcttttcaat taacttttgc
      181 gcaatttttt gattgataat acgagggatt tggtgattct tcttgacgat agaagtttca
      241 gcgaccatca ttcttgaaca gtgatagcac ttgaatcgac gctttctaag gagaattcta
      301 gtaggcatac cagttgtctc aaggtaagga atcttagacg gtttttgaaa gtcatatttc
      361 ttcaattggt ttccgcactc agggcaagat ggggcgtcgt agtccagttt ggcgatgatt
      421 tctttgtggg tatccatatt gatgatatct agaatcttga tgtttgggtc tttaatatcg
      481 agcagttttg tgataaaatg taattgttcc atatgaatct ttctaatgag ttgttttgtc
      541 gcttttcatt ataggtcata tgggactttt tttctacaac aaaataggct ccataatatc
      601 tataggggat ttacccacta caaatattat agagccaaaa ataatatgta aagagtcgag
      661 gaaatccctc ggctttttta tctttccttc gcttggtaat agatctctac ttcttttttg
      721 agatgagaca gcatagaagt ttcctcggtc agctctagga gtgagaaccc tttttggata
      781 agtttcgcat catccctaca aatcccaatg cggacatagc agatagccag cctatcgtag
      841 cttttcttat tcttggcgtc ctccagtaaa gtgtagcaga tttgcttaca catgttttta
      901 tcttgattgt atagatagag tgtggaaagg ttgagcagga ttgctattcg caagtcatat
      961 aaatgttgat agtttttata gacttctaag cgttgcaaga ttttctcgga ttattgacaa
     1021 ataaacggac attctgatag acgattgccc tagcggctta gtgtaaactt tacaaatttg
     1081 gcttgtaatt tttttataaa attcacttta gttacttgac agttattata ttttcgctca
     1141 taatatagat aaaaggatgg gataggagtt taaaaatttg aaagcgctat ccataatcat
     1201 aacgcataat tttctccttt tcgtgaaaaa agttaacgta attttgaaat gagcttaata
     1261 agaggtacta tgtaggtaga aaataaagat aggagaaaaa gtatgaataa aaaaatattt
     1321 tgtattctag tatgtattat atcattgatt agtctagcta tagtctttcc atggggctgg
     1381 tcgatataat gtaagggagc ttgagttgtt agtggaggat aaaatgttaa gagtaatagt
     1441 agttattcaa tctttagtaa taatactgct tgctgttgct ttattattat ctcggaaaaa
     1501 ctttgattcg ttaaatgttg ttcttataat gatgatcgta tcacaattgt tgttattagt
     1561 atatttgata aaatcaggga atcagtgatt agctgttatt tgaattaagt aaactgttaa
     1621 gcttcaagca gtaactggtt ttaaatattt aaaataagat aaaggaagga agtctaattt
     1681 aggtaactaa acaaagcctg cgatcacttg ttaggaaacc atcctaacca tgcttaataa
     1741 aaaaggagaa aataaatgga actcgtatta ccaaataatt atgttgtgat tgatgaagaa
     1801 gagatgatgt accttgatgg gggggggcta tatatatacc caggtgggca attacaggag
     1861 ccattactgg tgcagcatat gcagcattag cagcagcagg aggtggaggc cttcaactag
     1921 ttcttgcatc ttatggatta cgctccgcac tggtagctgg gattgttaaa ggtttaggag
     1981 tattaggaat tcatattgga aatgcttttg caaatactgt tattagaagt attgcatctg
     2041 ctggaattgg tgctggagct gattggattt ttaccaatat tattgatggc tgggatgggc
     2101 gacgtgatag tcaattgaga ataggttaat aatcttatgt tggttgtttt aatttcagtt
     2161 attgttgcat tcctgtatca taaaattaca gagtatgtca acaacaggaa aattgatatt
     2221 gttatttttc tatcattgct gatttctcat tttatttgga attactattt tttaccaatt
     2281 gaaatattga tagcaatcag tggagcaaat ttactattaa gttttttaaa aaaattacag
     2341 actaaataat attaatctgt gtaatacagt agctcggtca ttagattcta ttgaagatat
     2401 aaattaaaaa tgaggctggg aaaaaactca atttgaaaat gaaattgagt aaatttttct
     2461 attatataac gcatattatc aagatttttg aacacctgat aatatgcact tttcttattt
     2521 taaagatttt ttgcctttct tcatttcttg gatgaattgg agagatgact tgatttaggt
     2581 gtttgacatt actatagata ggatttagca gtactaatat gaactcatat tataggtgta
     2641 gacttaaatt ttggaagcaa gctaaaggat atcttatcta ggtaactaag tgctataaca
     2701 agatatattg gtggagttag tatggcaact attactaatg ctcttaatat tgcggctact
     2761 gttgctgaag tcttctcatt aggaggagcc attgcatatg gtttagatat cgtagacggt
     2821 aaatttgatg ggtatttatg ggcgtaaaac tatagctatg aaacattttt ttgcaggaat
     2881 tggtgaaatt cattttttgt tatttttatt atatctaagc atgtctgcta gtccaattat
     2941 tggactagtg attggatata ctaaaataaa tctaataaat tctattatta tagctcttgg
     3001 tatgatattg gcattaattt tggtattatc aagagtgtat agaaaatatt tttatagaga
     3061 cgatgatgac taaagttttt atcaataatt tgggctcctt gtcaactgta gtgggttgaa
     3121 gaaaagctaa cgtctgggga aggggttaaa gctttgcttt atcaaatatt gacttacaga
     3181 gttgctctat tgtattgatg tattcttagt aaataatatg gtgttttgaa tgaaagatga
     3241 tcagaaatat ttattagcgg gactttattc gcttctagtt gcaatatttt attttccatt
     3301 gattgagtcc aaggggattt ttgtaagtat attgatggcg gttttacttt tatatttaat
     3361 atacttcatt gcaacagtca ttcatattgt gataattaag tttataagaa aaaaatcttt
     3421 taagtatttg gttctatatc catttactta tgatgggagc tggagatttc aacctataaa
     3481 cttactctac tttccagaaa tggtgagaga tgtcattccg attaatttag ttcaagaata
     3541 ttgccaagga caaccttacg gactgttaaa aaagatgctg aaaagaattc gattgtcacg
     3601 agagatatct ttactcctgg ctaccattat cgtctatttt tttacgcata gaattctacc
     3661 tctttcagta tttacgttca tattttctta catattgcta tttgcacaat cttatttggg
     3721 tggtaatacc gcttggattg gaaatagaag attaataata gatgatgaat ttgaaaaaat
     3781 cttgctttca aaaagttata taaaagaaat atcatctgca cgatactcag aatacttgac
     3841 atgtgaatac aaaaacttta caccaatcat attgttagct atttttgaaa atttgcttga
     3901 ctcctacttg cttcagaatc agagtgaggt tgacttagat attttttata aagttttacc
     3961 tttgctttat aaagaaaaat atactatggg attcaattac tttgtaagtt taaattattt
     4021 actatataag gttggatttt tgggaatcat ttacgataat gaagcattaa gagatttgtc
     4081 aaaacaatat ttaaacaaaa atatttcgga attacaagat ggttctttcg aggacggtat
     4141 acaagatgct gttgcctcta aacaaatagt agttataaat gaatttatag cttgtttaaa
     4201 ttccagatgc gtgccatccc aatatgatag atttttttat aaagatagac cttatatttt
     4261 ttccagaaag agtcctatta aggggtgaaa atttgttaca tttggattaa caagtgtcct
     4321 agggattaga aataactcta gtatagctag atatttttga gtaactagaa atatcattag
     4381 tctacccata tgattgccag aaaagatggc tgatgaatct tatttatact gttgcagtag
     4441 gcgttgtcta ggataaataa gctatcttga tgggggagat tggaataatt ttagtagaaa
     4501 cattaaagga ttatggacaa gtagcgcagg attaggtgat gcaatgtgct aagttggctt
     4561 ggtgttagca gtagtattat ttaacaatgg aaagtagact aatgaaaaat aagcgttatt
     4621 tttttgacac aattttaata attttactgc ttataagcac gatattttgt gtcagcccag
     4681 tatttataaa attggacatc ttaggaactc cctctcatgc catcttaacc tttgtattgg
     4741 cgataccgtt attctatatt ttgtctcaat gcttacatac tttgctatta ctagtttcct
     4801 caatcttttg taaattaaga ccaatttatt tttattttat atttgtgatc attataggag
     4861 ctaggaaata ctatcgaatt ctctttcacc aactaatggg atttagtcca ggaatagcag
     4921 tgttttataa ggagagtcaa acaactaaga atctgtttaa attttactac ttcttgtact
     4981 ttacaacact aatttcatac tattttttct ttacttttgt gtatgacaaa tcgttgcttt
     5041 tgcctcttat tccattttct attatcatag cattagtaca aaaactttat agaattgaga
     5101 atcaacaatt atttctgtta aaatcaaaag tactaacaat actggaatct aagagggatt
     5161 gtgagtttaa tcttcaggat tatcatgaaa tttggaaatt gcaatcaaaa tctgagttgc
     5221 catgcgtggc tttatcttat atcagtttga tcaagccata tctttcagag agtgtgcgtg
     5281 aacaaattga tttattagaa gttaagcgat ttaaaaaaat aaatcatcca atatcacttt
     5341 atggtatgtt ggatgttata aaattaaatc tatatttacg gcattataat gaaaaaaata
     5401 aatatgaatc aatgttaaag aaaattttag aggtaagacc agactttgtt ttaatcgagc
     5461 agaatattga tgatagttta aatagctcgc aacccttatc tttatcttta gccatttcag
     5521 aaatccaact tttgcttgaa gtgtatatgg ggatcaaaca tgtttcaatt aggagataaa
     5581 accagaataa tatttgccat tataggggca agttgcatat tagtcagtat gtatcttatt
     5641 ccacttatta aaactgagaa taaattttgg gaaatacttt tatttatatt aggtgtattg
     5701 ctaattggaa ttgcgttact aagtcaaaaa aaataaattt tgaaatagta ttagtgagtt
     5761 cgcaatcatt tattgctagt ggtttagaac tgttaagttt caaacaataa ttgattttaa
     5821 accttaggta acctataaaa acaaataagg tagagaaagg atatcttata taggtagcta
     5881 agtgataaaa acacagtcgt ctatcacttg ttaggaaact atcctaacta tgcttaataa
     5941 aaaaggagaa aataaatgga actcgtatta ccaaataatt atgttgctct tgagcaagaa
     6001 gagatgatgt atcttgatgg gggattttct attctgagat gacctgttgc aacagccatt
     6061 aatatagctt ttaatggtgt tttaggtgga ggagcaatca gtctagttag aaattatatt
     6121 cgtaattatg gtttgcggcg agttacaagc gcaattgctg gagcagctgc aagatatgtt
     6181 ggggtacgag ttgcaaatag agtggcagga tttgcactgt ctgctattaa tggatttgca
     6241 gcttggatgt caattggcga tgctattaca acaatctggg ccaacaatga tgtaaatagg
     6301 agagacccaa atttaaacgc cttgtggtaa ctagatatgg gtattaaaat ggaaaaaatt
     6361 tttgttatta ttttttttgt atgtttattt atatcatcca taactttttt agcctatgat
     6421 tttgttagcg aagaaataaa aaagttgatt atttggatga atgtcgtttt tttgatttta
     6481 atcatagcaa tgataattta tccaaaatca agaaaatgat aaggacactg taaaattatg
     6541 atacgtaaac taatcatttt tttattaatg ctccctcttt ttgtcttgtg gctagagttg
     6601 catgtcctag tgaataactt gcaattgaat ctagaaattc cctttgattt tgtggttagt
     6661 acgagtctta ctttttttgt tttgatatta tcaaaaatag ttttagacat actatacgca
     6721 ttgaaagatt tgtacaagaa agaagctctt attacgattt ttccctttat ttttataaga
     6781 aggaaaaaag tgaatgtgag attctcgccc tatttttcat tccatcgtaa aagtttgtcg
     6841 cctgatgatt taagatctag gattatatgg agttttattc ttgaaattgc tattatccta
     6901 gtatttattt taaaaattcc ttttgcaatc atcatgctta ctacaatatt tttctggact
     6961 ataatggata tcaatcatct cgtttttaat aagacggaat ttctttttaa tcaaaacaaa
     7021 tggcaaaaag aagattcgtt tgaaagtgat ttgacgaaaa cgttaaagga taagatacaa
     7081 aaatcagagc taagttattc tgacttaatg tctcttcagc tgtatgatgc gatgaaccaa
     7141 tccacctttt taacggatag tgaacttttt gaggatattt tgaaaaaaat cgaagattct
     7201 cataacaccc ttctgtgtac aggtcttgtc gagttactgc tgtatgaaat ttctattagt
     7261 aacaataaca actggcaaga aaaggttgat aaaattagaa tacagctcat cagaatcaat
     7321 caattagatt ttttctatta tacaagttgg ttaaggcaaa attttgattt ctgtatgaat
     7381 agagagtatc ataaaatgaa atctcggaaa ttattactga gtaataaaaa gatagtttaa
     7441 gttcgtccta tttgtaaaac aaatgaaaca atttcaacta aggaggagaa aataaatgga
     7501 acttgtatta ccaaataatt atgttgtgat tgatgaagaa gaaatgatgt attttgatgg
     7561 gggagcttat ttaagcaagc gtgcttgtca aggaatttgc gcagctttag ctatgagttc
     7621 aggaactttt atagcattag ctggagctgc agttttaacc aaaaaactaa taaactatat
     7681 taaggttgga ggtcttggag gctggcttat tggtgcagca gcaggtgtat tggctacagc
     7741 agcagggaaa atagcttact atattggata tggtgttctt aatagaggtt gtgatattaa
     7801 cgggaaccct tatccttggg atggattcat atctgcaaca gtaagatgag taatgtagat
     7861 aagattcgaa aaatacacat catcgtgtgt tgggtgtata tatttttatc attcagggcg
     7921 attataaatg atacggagta ttttttgctt atttttttag cttttatcta ctcaatagta
     7981 tcactacctc tatattctgt gaaaaataaa atagtatcta tctgtctagc cataaattcg
     8041 attctgttaa tgagtttccc cattttaatc aataagtttt tcccagaaag ttttttgact
     8101 tataccgtat taataagtgt ttttattaca gagttgataa tttttcattt aattgggaaa
     8161 gattttgata ttaaattgac taacgaatat aagaaaatta gtcagtttag aagcaaggtg
     8221 tctcaatctc cttggataaa atatttagag atttctagtt ttatattaac tatatttcca
     8281 tctattcttt atggtacagt tgataatcat gtactgactc ttatcttttt gataaaaatt
     8341 tgtgtagata ccacgataaa atttttattc atcagattat ttgacacaag tactttaatg
     8401 aagaggagaa tattttttct tttcgcattg gatgttatag cttacttatt tttaggatat
     8461 cttttagtga ttcaaaaagc aggctatttg ttttcggttt tacttctttt ttctaatttt
     8521 tcagttccat ttatcaaaga aaaggaatac gaattattta aaaatagcaa gtaatagaaa
     8581 cataggttaa atcttagaac ggcttaaaat cagatatgat aaagggaaat agtcttatct
     8641 aggtaactaa gtgctacaaa cacagtcgag gatcacttgt taggattaca ttttaatcat
     8701 gcttaataag aatggagaat tcctatgggg attgtattac tctgaagttt cgaatacctt
     8761 agttctcgtg attttgagct attctagctt tagaatcctt cagaatgtaa aattttaagc
     8821 agtcaaagac ttagaatagc ctgaaaacat ttattttata gcgattctaa gcttagaatt
     8881 gattggatat atatgtattt gagctgctcg atagttagga cagctctatt ctgagaaatc
     8941 tgagctatca atgcttcaga atagtatttc gccaatggtt tttattgaag aggtgattgt
     9001 tttatgatag tctaaaataa aactgattta atggagtaaa tggagaatcg ttacatgaaa
     9061 catttttttg taggaattgg tgagataaaa cttgttggct acttattgta tatatgtgta
     9121 ggactagccc ctctttttca tatatatgtc ataggttcgg aactgagttt tgtgaaaata
     9181 gtgttatcta ttttgggagt tatatttgta agtatgttaa ctattgctcg aatttatagg
     9241 acttttttct ataaagaata gtttggactt gaactgtatc taaaaacaga ggttggtcga
     9301 ttatcagcct ctttcttgtc gttgaaaaga gtgagatata ttgacttttg aaaaaaagat
     9361 gtcataattg agttgggata aacctaaaag taatatagta gattgaatct ggaatagtcc
     9421 gttatgactg ttaaaatatt tctagaaatt aatttgactt tcctaatcga tttgttcaca
     9481 tcttgtttca atctactata ctttctcgtt aaaccgttcg gcaattcatg gtgacatgga
     9541 cacatagtag taagcacact atgtggcttg gcagagctaa aaactgttcc cttgcgataa
     9601 gcctaataag cataacatag ggagttagag aagccgactc taatcaacca ctttgggcag
     9661 tagtgagaac tgccccgtgc ttttttattt tgagaaaata tggagtttgt cgttgaaatt
     9721 acttgattgt attttggact atcaagaaag attcaatgga aaaacatgtc aagtatcaac
     9781 gaattataag tatttagaga ttttcaaagt gaatttttgc ttgactgatt tacatcattt
     9841 atttgactta tacaaaatca cacgagatta tgctagtcaa acaaaacctg ctattcaagc
     9901 tggtgttttt attttagaag attttagaaa tatcctatgt acaatgatgt aatcgaaagg
     9961 atatctttat atgagtttat cggtgatatt ttctattcta aaataataag ttgttgcatc
    10021 gtagctaggg atttatctaa aaatactatg aaattggacg tcatattttt tgaggataaa
    10081 aataaaagat ccgcagtttt aggtttacga agagacaaaa gcggagtatt taaatcagtt
    10141 attctacatt ttacaagcgc taagaaatat gctaaagttc gtaaaacaga tgtgaaagaa
    10201 atgaaatggc tataaagatt gtccgcaggc ttaagcttgc gttttttgtt gtttaacgaa
    10261 attaaaaaac aagctctctc atcggaaatg tttttatagg aatgaaggaa gatgatgcta
    10321 tgtttaaaaa gagaatcgaa aagggcaaaa gtagtgtctt tatctttttg gagtagaagc
    10381 ttatgatata gaaatttgta ataaaaatgt aatataaaac atttgacaaa tatttacggg
    10441 gggactatac ttaatataag tatagtctaa aaatgactat cagaaaagag gtaaatttag
    10501 atgaataaga aaaaaatgat tttaacaagt ctagccagcg tcgctatctt aggggctggt
    10561 tttgttgagt ctcagcctac tgttgtaaga gcagaagaag ctcccgtagc cagtcagtct
    10621 aaagctgaga aagactatga tgcagcgaag aaagatgcta agaatgcgaa aaaagcagta
    10681 gaagatgctc aaaaggcttt agatgatgca aaagctgctc agaaaaaata tgacgaggat
    10741 cagaagaaaa ctgaggagaa agccgcgcta gaaaaagcag cgtctgaaga gatggataag
    10801 gcagtggcag cagttcaaca agcgtatcta gcctatcaac aagctacaga caaagccgca
    10861 aaagacgcag cagataagat gatagatgaa gctaagaaac gcgaagaaga ggcaaaaact
    10921 aaatttaata ctgttcgagc aatggtagtt cctgagccag agcagttggc tgagactaag
    10981 aaaaaatcag aagaagctaa acaaaaagca ccagaactta ctaaaaaact agaagaagct
    11041 aaagcaaaat tagaagaggc tgagaaaaaa gctactgaag ccaaacaaaa agtggatgca
    11101 gaaaaatatg ctcttgaagc taaaatcgct gagttggaat atgaagttca gagactagaa
    11161 aaagagatca aagagattga tgagtctgac tcagaagatt atcttaaaga aggcctccgt
    11221 gctcctcttc aatctgaatt ggataccaaa aaagctaaac tatcaaaact tgaagagttg
    11281 agtgataaga ttgatgagtt agacgctgaa attgcaaaac ttgaaaaaga tgtagaagat
    11341 ttcaaaaact cagacggtga gcaagctgaa caatatcttg ttgcagctga aaaagactta
    11401 gatgctaaaa aaactgaatt agaaaaaact gaagcggacc ttaagaaagt agctaatgag
    11461 ccagaaactc cagccccagc tcctaaacca gaaactccag ccccagctcc agaagctccg
    11521 gctccagctc cagaagctcc ggctccagct ccagaagctc cggctccagc tcctgcacca
    11581 aaaccagagc aaccagctcc agcaccaaaa ccagagaagt cagcagatca acaagctgaa
    11641 gaagactatg ctcgtagatc agaagaagaa tataaccgct tgactcaaca gcaaccgcca
    11701 aaagcagaaa aaccagctcc agctcctgca ccaaaaccag agcaaccagc tcccgcacca
    11761 aaaacgggct ggaaacaaga aaacggtatg tggtacttct acaatactga tggttcaatg
    11821 gctacaggtt ggctacaaaa caacggttca tggtactacc tcaacgctaa cggttcaatg
    11881 gcaacaggtt gggtgaaaga tggagatacc tggtactatc ttgaagcatc aggtgttatg
    11941 aaagcaagcc aatggttcaa agtatcagat aaatggtact atgtcaacag caatggcgct
    12001 atggcgacag gatggctcca atacaatggt tcatggtact acctcaacgc taacggtgct
    12061 atggcaacag gttgggctaa agtcaacggt tcatggtact acctcaacgc taacggttca
    12121 atggcaacag gttgggtgaa agatggagat acctggtact atcttgaagc atcaggtgct
    12181 atgaaagcaa gccaatggtt caaagtatca gataaatggt actatgtcaa tggcttaggt
    12241 gcccttgcag tcaacacaac tgtagatggc tatgaagtca atgccaatgg tgaatgggtt
    12301 taagccgatt aaattaaatc atgttaagaa catttgacat tttaattttg aaacaaagat
    12361 aaggttcgat tgaatagatt tatgttcgta ttctttaggt acctgtctta tgatttcagg
    12421 aaatgtcatt aaaaaaacga ctccttttct ctaacttgaa aaatagatta gagaaaatgg
    12481 gttgttttat ttattatagt tatttgaatg aagataagaa gaaggtatac tcacatcatt
    12541 cacataatct gtatgttgac tataagttta aaaaaacaat ttttaagctc ttccttgtct
    12601 tctccaacca agcgtgttat aatgaatact gctcaagcga ccttcaatcg tgaagcacac
    12661 acgaccttca atcgtgaata aacgaataga tgggagactt accatgagtg ataactctaa
    12721 aacacgtgtt gtcgtgggga tgagtggtgg tgttgattcg tcggtgacgg ctcttttgct
    12781 caaggagcag ggctacgatg tgatcggtat cttcatgaag aactgggatg acacagatga
    12841 aaacggcgtc tgtacggcga ccgaagatta caaggatgtg gttgcggtgg cagaccagat
    12901 tggcattccc tactactctg tcaattttga aaaagagtac tgggaccgcg tttttgagta
    12961 tttcctagcg gaataccgtg cagggcgcac gccaaatccg gacgttatgt gcaacaagga
    13021 aatcaagttc aaggcctttt tggactatgc catgaccttg ggggcagact atgtagcgac
    13081 tgggcattat gctcgagtgg cgcgtgatga ggacggcact gttcacatgc ttcgtggcgt
    13141 ggacaatggc aaggaccaga cctatttcct cagccaactt tcgcaagaac aactccaaaa
    13201 aaccatgttc cctctgggac atttggaaaa gcctgaagta cgcagactag cagaagaagc
    13261 aggcctttcg actgctaaga agaaagactc gacagggatt tgctttatcg gagaaaagaa
    13321 ctttaaaaac tttctcagca actacctgcc agctcagcct ggtcgcatga tgactgtgga
    13381 tggtcgcgat atgggcgagc atgcaggtct tatgtactat acaatcggtc agcgtggcgg
    13441 actcggtatc ggtgggcaac acggcggtga caatgcccct tggttcgttg tcggaaaaga
    13501 tctaagcaag aatattctct atgtaggaca aggattctac catgattcgc tcatgtcaac
    13561 tagcctagaa gccagtcaag tccactttac tcgtgaaatg ccagaagagt ttacgctaga
    13621 atgtacggct aaattccgtt accgtcagcc tgactctaag gtgaccgtcc atgtcaaagg
    13681 agacaaggca gaggtcatct ttgcggaacc acaacgcgcg attacaccag gacaggcagt
    13741 tgtcttttac gatggcgaag agtgtctagg tggtggtttg attgacaatg cttaccgcga
    13801 tggacaagtt tgtcagtaca tttagattga caaattttct caatttgcta caataataac
    13861 agcaatagaa atgatggtca aagctcatgg atgttgcagg cttttttgtc ctgcacttct
    13921 ttgtagtttt gactgttttt gtgtcgttta agggaaagga caagaatgac tcaacaagac
    13981 tttcggacaa aagtagacaa tacggttttt ggtgttcggg cgacagcctt gattgtccaa
    14041 aatcacaagc ttctagttac caaagacaag ggcaagtatt acactattgg aggtgcgatt
    14101 caagttaacg aaaaaacgga agacgcggta gtccgtgaag tgagggaaga actgggtgtt
    14161 aaagctcaag ctgggcagct agcttttgtg gttgaaaatc gttttgaagt ggacggcgtt
    14221 tcctatcaca atatcgagtt tcattatctg gtggatttgc ttgaagatgc cccgttgacc
    14281 atgcaggaag atgagaaaag tcagccctgt gagtggattg acttggataa gcttgaggat
    14341 atccagctag ttccagcctt tttaaaaaca gccctaccag attgggaagg ccaactaaga
    14401 cacattcatc ttgaggaata ggagagaaac atgatttatc attttactga agaatacgat
    14461 attattgtaa ttggtgcggg acacgctggg gttgaggctt ccttggccgc tagccgtatg
    14521 ggctgtaagg tcctgcttgc gaccatcaat attgaaatgc tggctttcat gccttgtaat
    14581 ccctctatcg gtggttctgc caaggggatt gtcgtacgtg aagtcgatgc cctcggtggc
    14641 gagatggcca agactattga caagacttac atccagatga agatgctcaa cacagggaag
    14701 gggccagctg tccgtgctct tcgtgcgcag gctgacaagg aactttactc taaggagatg
    14761 cgcaagacag ttgaaaatca agaaaatctg acccttcgtc aaaccatgat tgatgagatt
    14821 ttggtggaag atggcaaggc tgtcggtgtg cgtacagcca cccatcaaga atatgctgct
    14881 aaggctgtta ttgtgacgac agggactgct ctccgtgggg aaattatcat cggagacctc
    14941 aagtactcat caggtcctaa ccacagcttg gcttctatta acctagctga caatctcaag
    15001 gaactgggtc tcgaaatcgg tcgtttcaag acaggaaccc ctccacgtgt caaggcttct
    15061 tctatcaatt acgatgtgac agaaattcag ccaggagacg aagtgcctaa tcatttctca
    15121 tacacttcac gtgatgagga ttatgtcaag gaccaagtac catgctggtt gacctatacc
    15181 aatggtacca gtcatgagat tatccaaaac aacctccacc gtgcgcctat gtttacaggt
    15241 gtggtcaagg gagtgggacc tcgttactgt ccatcgattg aggacaagat tgtgcgcttt
    15301 gcggacaagg aacgtcacca actcttcctt gagccagaag gacgcaatac agaggaagtc
    15361 tatgttcaag gactttcaac cagtctgcct gaggatgtcc aacgtgactt ggttcattcc
    15421 atcaaaggtc tggaaaatgc agagatgatg cgaacaggtt atgctattga gtatgatatg
    15481 gtcttgcctc atcagttgcg tgcgactttg gaaaccaaga aaatctcagg tctcttcact
    15541 gctggtcaga caaatggaac gtcaggttac gaagaggcag caggccaagg gattatcgcg
    15601 ggtatcaatg cggctctgaa aatccaaggc aagcctgaat tgattctaaa acgaagtgac
    15661 ggttacattg gggtcatgat cgacgacttg gtgaccaagg gaaccattga accttaccgt
    15721 ctcttgacca gtcgtgctga atatcgtctc attcttcgcc atgacaatgc tgatatgcgc
    15781 ttgactgaga tgggccgtga gattggcctt gtggacgatg aacgctgggc tcgttttgaa
    15841 atcaagaaaa atcaatttga taatgagatg aagcgtctag acagtatcaa actcaagcca
    15901 gtcaaggaaa ccaatgctaa ggttgaggaa atgggcttca agccgttgac agatgcggtg
    15961 acagccaagg aattccttcg ccgtccagaa gtttcttacc aagatgtggt ggccttcatc
    16021 ggaccagctg cagaggaatt agatgacaag attatcgaat tgattgaaac agaaatcaag
    16081 tacgaaggtt acatctcaaa agccatggat caggttgcta agatgaagcg catggaagaa
    16141 aaacgtattc cagccaatat cgactgggat gacattgatt ctatcgcaac cgaagcccgt
    16201 cagaagttca aactcatcaa tccagaaacc atcggccaag ccagccgtat ttcgggagta
    16261 aacccagcag atatttctat tttgatggtg tatctggaag gtaaaaatcg tagtatttct
    16321 aaaactcttc aaaaatcaaa atgatacgtc gtaggcttct tacgaatgag ttcaaagctt
    16381 ggctttgatt catctccaac ctcccatagt tccccgaact atgggagcta actcaagtta
    16441 tgcattttcc tagccttctg gtctgatttt cattgagttt taatctcaaa agaaagcata
    16501 gagaaaaaca gctccgaaga cggggctgtt ttgttgcttt attcttcatc tggtgtgagg
    16561 atcatcggga tgatgatcgg ttcacgttcg gtattttcat agaggaaggg gcgaatagcg
    16621 ttgacaatgg caccattgac agattgcacg ctagcatcct tatttttcag tgcgatacga
    16681 atggcattga agaggatacg ctggctttgg cgaatcaagt ctccagactc tctcatgtag
    16741 acaaagcctc ggctgaggat atctgggcca gacagaatca tctgcgattt gaagtcaaca
    16801 gttgcgactg ccagaacgac accgtcttca gatagatcgc gacgatcttt gaggacagct
    16861 gcgccaattt caccgatacg atttccatcg acatagatat cttgggcgtt gaaatgacct
    16921 gcgatacgag ctgagtcagc agtaagggca agcacatcgc cattgctcat gataaagata
    16981 ttgtccttct caacaccagt atccactgct agtccagcgt ggactttttg catgcggtat
    17041 tcaccgtgga caggcatgaa gtattttggc ttaatcaagc agagcatgag tttttgctct
    17101 tgctgaccac cgtgtccaga tgtatggata ttgttcactt taccgtggat aacttcgaca
    17161 ccagcttcag aaatgatgtt aatcagcttg ttgacgctag tagtgtttcc agggatggga
    17221 ctagaagaga agataacggt atcacctggt tgtaattgta cttgacggtg ggttccgttg
    17281 gcgatacgag agagggctgc cataggctca ccctgactac ctgtacagag gataagaact
    17341 tctcctgcag gataatcttt gatttcattt ggctcgataa aggttccctt aggagctttg
    17401 atgtagccaa gatcgattcc gttgacaatg gccttttcca tagaacgacc aaagaccgca
    17461 atcttgcgtc cagtcttaac agcagcttct gttgcctgct ggagacggaa gatatttgag
    17521 gcaaaggatg caaagatgat acgtccttca ataccttgga taatcttcat aatggactga
    17581 ccaacgactt tttcagagtt ggtaaaggtt ggtacttccg catttgtcga gtcagacagg
    17641 agacagagca cgccttcttc accaagcgca gccatacgat gcaagtccgc aggttctcca
    17701 actggagtaa agtcgaactt aaagtcaccc gtacagacga ttttcccttg aggagtatga
    17761 atgacaatcc ccaaaggctc tggaatagag tgagtcgttc taaagaaagt tgccttgaga
    17821 tttttaaagg tcaactcggt gttgtggttg atttcgtaaa gtttggcgtt gcgcaagagg
    17881 ccgtgttctt cgagtttccc acggatcaaa gccaaggcaa gcggtccagc ataaataggg
    17941 acatttgctt gcttgagtag gaacggaatc ccaccaatgt ggtcctcgtg tccgtgtgtg
    18001 attaaaacag ccttgacgcg gtcgatattg tctacgatgt aagagtagtc aggaatgaca
    18061 tagtcgatac caagcaagtc atcttctggg aatttaatcc cagcatcgac gatgataatc
    18121 tcgtcttggt attcaattcc gtaagtgttt ttcccgattt ctcctagacc accgatggca
    18181 aaaacaccaa cttcttcagg tttaagagtg taggccatat tagaactccg taatttcgaa
    18241 ggcgccagtt tctttttcgt aatcgagcaa tttgtcagac aagagttcga tatattcgat
    18301 attgtactct gggcgatttt cttcgacaag ttggcgagca gtgatacggc cctcaagttc
    18361 tgagctggta tcgatgtcta ggtaaagcgc gcgtgttgtt tcacggcgtg ggctacgttc
    18421 ttttgtttct tgataaaaaa ctttgtaaat catatagttc ctttctattt acaggtcagc
    18481 ttattccaaa cttttagcag atatttgctt gatttcattc cattttgtgt ctagattgac
    18541 cttgattcgt tacaattatt tcaattatac cacaaaatga aaaattagta aaagacggaa
    18601 acgagaaagt taggggacga tttctttggt gagcgtttgc aaaaataaag aaaatgtatt
    18661 atgttgataa cggaagtgaa atttattgct tgtcataatt ccatatagat tttaagtcaa
    18721 ggaggttgcc ctatgtataa cttatttgct tttgctatcg gagttcgttt gttagctttt
    18781 atcgtttttg ttgcttgcgt ttatggagga aatcttctat ttgccaaact ggaacgatga
    18841 caaatcaagt tcttgaggaa aattaccttt gtgactctct actcgctttt tctcctcctc
    18901 gtgacctatg tcgtttggtt tgtattttac tttggattaa atgcttagat gccctgctta
    18961 tgctggggtt ttttgtttgg ggatgtagag atagtagatt tacgacacga aaattccacc
    19021 ccatctatca agatgaggtg gtctttgcat ttttctaaaa tgacatgaca atggaatttt
    19081 caaagcttat tatttttatg ggagtcattg ttctgctcaa aaatagagtt gaagcataaa
    19141 aataaaacaa tacaaacaga taaatcgaat ggtaaaggga tagtagtaat gttcaaatca
    19201 ttgagaatgc tgagcaaact gtaagagatg aagacaataa aatttatcct tctaaaaatg
    19261 tgtttcttat ctagcatgat ttaccaaact ttttacgaag gtcttttcca atggcataac
    19321 ctgccataaa taaagcgata ccaacaccta caccaaagcc acccttgatt tcttgcaatt
    19381 ccttattaga aatttcacga tagttgttca aatttttcat catattaatc tcctcctaaa
    19441 aaataaccag ctgccaaacc agaacctata agtgctgttc cacctgcaat agctttccaa
    19501 gatactgcta ctccaaagat aaccaaggga gcgagaccgc catcaatatc tgataattca
    19561 ttttcagata aggataaaaa ttgattgtca agaatgtcaa aatttgtcat tgaactttcc
    19621 tccttttttc ttgttcactt ttatattcgg aaaagaaaag gaaaagtgag cattttttta
    19681 aattattttt agttaagtga gggcactctt gtctgggggc aaagaaaatt cccatgtgcc
    19741 agcttttgta gtataatagt aagcagacaa aaagatagga atgtgttatg aaagtattag
    19801 cttttgatac gtccagcaag gctctttctc tcgctatttt agaggacaag cagattcttg
    19861 ccgagatgac gattaatatt aagaaaaatc acagtattac cctcatgcct gccatcgatt
    19921 ttttgatggc aagtttggac tggacaccca aggatttgga ccgaatcgtg gtggctgaag
    19981 ggccaggtag ctacacaggc ttgcgaattg cggtagccac tgccaagact ttggctcata
    20041 ctctgaacat cgagttagtt ggtatgtcta gcctcttggc tctggtaccc taccaacaag
    20101 aaggcttgtt tgtctccttg atggatgcgc gtcgcaacaa tgtttatgca ggattttatg
    20161 aaaatgctaa acctgtcatg ccagaagcgc acctatcttt tgaagaggtg ctagaaaaag
    20221 tcaagggtgc tagtcaggta acctttgtcg gagaagttgg cccctttgtt gagcagattc
    20281 aagaatactt gccaaggact aattataaag aaaccttgcc taatgcagcc aatcttgctc
    20341 ttttagcttg ggacaaggaa gcagactcct tgcatgattt tgtgccgaat tacctcaaac
    20401 gagtcgaggc tgaggaaaac tggctcaaga accataccga gtctggcgag tcttacatta
    20461 aacgcctatg atagaaatca agcgaattca acaacagcct gacctagctc aagccatcta
    20521 cgctgttatg gcagctgttt acctagtcag tccttggact ctggagcaaa tccaagcaga
    20581 tctgtcccaa gaccagactt ggtatgcatt ggcttatgat ggggcagaag tgattggatt
    20641 tctagctgtg caggagaatc tttttgaagc agaagtcctg caaatcgctg tcaaaggagc
    20701 ttatcagggt cagggaattg cgtcagcctt gtttgctcaa ttgccgacag acaaggaaat
    20761 tttcctcgaa gtcagacagt caaatcaacg agcgcaagca ttttacaaga aagaaaagat
    20821 ggcagttatc gctgagcgaa aggcctacta ccatgaccca gtcgaggacg ccattatcat
    20881 gaagagagaa atagatgaag gatagatata ttttagcatt tgagacatcc tgtgatgaga
    20941 ccagtgtcgc cgtcttgaaa aacgacgatg agctcttgtc caatgtcatt gctagtcaaa
    21001 ttgagagtca caaacgtttt ggtggcgtag tgcccgaagt agccagtcgt caccatgtcg
    21061 aggtcattac agcctgtatc gaggaggcat tggcagaagc agggattacc gaagaggacg
    21121 tgacagctgt tgcggttacc tacggaccag gcttggtcgg agccttgcta gttggtttgt
    21181 cagctgccaa ggcctttgct tgggctcacg gacttccact gattcctgtt aatcacatgg
    21241 ctgggcacct catggcagct cagagtgtgg agcctttgga gtttcccttg ctagcccttt
    21301 tagtcagtgg tgggcacaca gagttggtct atgtttctga ggctggcgat tacaagattg
    21361 ttggggagac acgagacgat gcagttgggg aggcttatga caaggtcggt cgtgtcatgg
    21421 gcttgaccta tcctgcaggt cgtgagattg acgagctggc tcatcagggg caggatattt
    21481 atgatttccc ccgtgccatg attaaggaag ataatctgga gttctccttc tcaggtttga
    21541 aatctgcctt tatcaatctt catcacaatg ccgagcaaaa gggagaaagc ctgtctacag
    21601 aagatttgtg tgcttccttc caagcagcag ttatggacat tctcatggca aaaaccaaga
    21661 aggctttgga gaaatatcct gttaaaaccc tagttgtggc aggtggtgtg gcagccaata
    21721 aaggtctcag agaacgccta gcagccgaaa tcacagatgt caaggttatc atcccccctc
    21781 tgcgactctg cggagacaat gcaggtatga ttgcctatgc cagcgtcagc gagtggaaca
    21841 aagaaaactt tgcaaacttg gacctcaatg ccaaaccaag tcttgccttt gataccatgg
    21901 aataaagagt ggctctttgt caagtgtagt gggtaggcga aaagctacaa tctggagagt
    21961 acgaaattcg tactctcttt tttgatgttc aaagtcatca aaatccgttt tttaaaattg
    22021 ttaaagttcc ggaaaccaaa ggctttgcac ttgataacct taatcaaatt attggtcgct
    22081 tcaagtttag cgttggaata aggcagctta agtgcgttga taatcttatc tctatccctt
    22141 aaaaaagtcc aaaagaccgt ttgaaaaagc ggatgaaccg ttggcagttc ttgctcaatc
    22201 aatccaaaga aatggtcggc attcttctct tgaaaatgaa agagcaggag ttgatagagt
    22261 tcgtagtaaa cctgtaatcc ctcagagtaa gaaagcagct tatctcgtac ttcccgatgg
    22321 gttaagtgca ttcgaaacgt gggctgatag aatcgtttct gacagagctt gaagctatcc
    22381 tggtgtagta aatcagtcca gtggactgat ttagcccgag cctagaaacg aaaaagcgag
    22441 ggttccaaaa gcgcttgagc gcccgatact ccaaggattt tcggtcaaat tggttcatga
    22501 tttggattcg tactcggttc atagctcggc tcagatgttg gacaatgtgg aagcggtcaa
    22561 gaacaatctt cgcctttgga aagagttgct tagcgagccg ataataaggg ctgtacatgt
    22621 ccatggtgat gacctcgacc agctcccgaa cctctctctg atagcgttgg aaatggtttc
    22681 gaatcaccgc atgagttcgc ccgtctaaaa ttgcgaggat ggatttggac tcaaaatctt
    22741 gggcaatgaa gctcattttg ctctttttga agctatactc atcccaactc ataacttttg
    22801 gcaacttggt ccaatcggtt tcaaacttaa attccctcag ttttcggatg atggtggaag
    22861 ttgagaccgc caatctgtgg gcaatctcag tcatagactg cttttcaagg aggagctgag
    22921 cgattttttg tctcaccatg ttggaaatct ggcaattttt cttgacaatg gatgtttgag
    22981 aaacgaccac cttaaggcaa ttcttgcact gaaagcggcg ctttttgaga tgcagtaccg
    23041 tgggtaaacc ctgacagtcg agaagcggaa ttttagaggc tttctggaag tcgtatttga
    23101 tcatcttccc ttgacaatga ggacaaggag gagcggggga atccaacttt gcctgaacga
    23161 ctagatgggt ttggtatttc agaacagaca agattttgat atttttgtct tccaatccga
    23221 gcaaatctgt ggtattctta agttgttcca tatgaaccct ttctaatgag ttggttagac
    23281 gcttttcatt ataggtcata tggggctttt tttctacaag aaacgaccct ataattcctg
    23341 gggtgggatt acccactaca gaaattatag agccaaaaca ttccaaagtc ttgtctgact
    23401 ctggaatgtt ttctgttcac agttgttttg taactgccta ataagtaacc gcgctataac
    23461 gaggtatcta ccgagattgt caattctcca gtatactgtt ataaaaaaca aaactggagg
    23521 atttttttat gtccccccat cgtcccatcg actgttccgt agctgcccaa taacggagta
    23581 taatcagatg aaacaagaat aggacaaaag tgcctcaaga aaagcatcgt aatttgacaa
    23641 tattattctg agatgttttt gatgtaagcc catattttct caatgggatt atactcgggt
    23701 gaataggtag gaagtggtaa cagtctatgc cctgctcctt acacatgttc attctgtgaa
    23761 accttgcatt gtccataatg ataagggatg gtgtatctaa agtaggtagt aagaattttt
    23821 ggaagcaagc ttcgaaaaag tcactcgtca tcgtatcttt ataggtcatc ggagccatag
    23881 tatattgaaa caaaaaaggg cattagtact tctataacag tatcgcaatc tctggtgtgc
    23941 gttgtctcga tcttaattca aataattata tcttcttcca gagagactaa ctgcctgctc
    24001 aaggctcgat catattcgag ataaaaataa gtctcaaccc ctgtctcata aatataaata
    24061 ggagtcaggt agcttaagtg attcaattct ttaaggaacc gatttacttt ttctgggtct
    24121 tgttcgcagt aggtacggct cttttttaga ctatatccca tagcctttag agcgtaatga
    24181 atagttgttg gaggacagtt gaattcagca gctatttcag tcaaataagc atcgggatga
    24241 gtttcaatat agatctttaa tttatctcta tcaacttttt caattaatag tggaagtttt
    24301 cttaaagtta gtgtgttgaa acgtttttat acagtgctaa aatttgaagt gtagtgcaga
    24361 tgtatttgta atagtattat agcaattctt tggagaaggt cgagacaaga gaaaataggt
    24421 atctttgaga tataagcatg atttactata aaattattga gttattcata aaaatttctc
    24481 tatcaaatat cataatgcgt cgtttaagga gatggttaca atgcaatatt aaggagatgg
    24541 ttacaatgca atatagttgt ggaaaaataa atattaatat ccctgatgga tatggagaca
    24601 ttaaggatat agtgttttcg gctcatatta tagttaggta taataatgga cattgtggag
    24661 gtatagatcc gcatataatt ggactttgta aaaagcagat cagaaggatg tctctatatc
    24721 ctattttgat aatcgtatct agagattcaa aggttattga tgattata
//
LOCUS       DAVKXA010000033        22745 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKXA010000033 DAVKXA010000000
VERSION     DAVKXA010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.033"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1849..3230
                     /locus_tag="VW883_001384"
                     /pseudo
     CDS             1849..3230
                     /locus_tag="VW883_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            3211..3414
                     /locus_tag="VW883_001385"
     CDS             3211..3414
                     /locus_tag="VW883_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274513.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            3417..3767
                     /locus_tag="VW883_001386"
     CDS             3417..3767
                     /locus_tag="VW883_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274514.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            3776..4075
                     /locus_tag="VW883_001387"
     CDS             3776..4075
                     /locus_tag="VW883_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274515.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE"
     gene            4079..4411
                     /locus_tag="VW883_001388"
     CDS             4079..4411
                     /locus_tag="VW883_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0274516.1"
                     /translation="MQQITEIIIAFATGFLAVAVGGIVKAVKDYLLRKGGEKAVIIAE
                     ILAKNAVHAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            4415..5371
                     /gene="lytA"
                     /locus_tag="VW883_001389"
     CDS             4415..5371
                     /gene="lytA"
                     /locus_tag="VW883_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0274517.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKHTDGNWYYFDQSGEMATGWKKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5623..6588)
                     /locus_tag="VW883_001390"
     CDS             complement(5623..6588)
                     /locus_tag="VW883_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0274518.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            6724..7581
                     /locus_tag="VW883_001391"
     CDS             6724..7581
                     /locus_tag="VW883_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0274519.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            7568..8347
                     /locus_tag="VW883_001392"
     CDS             7568..8347
                     /locus_tag="VW883_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0274520.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            8371..9723
                     /locus_tag="VW883_001393"
     CDS             8371..9723
                     /locus_tag="VW883_001393"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0274521.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTIEEVDYYVDTITDVVRAEIGID
                     "
     gene            9797..10171
                     /locus_tag="VW883_001394"
     CDS             9797..10171
                     /locus_tag="VW883_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0274522.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            10173..11021
                     /locus_tag="VW883_001395"
     CDS             10173..11021
                     /locus_tag="VW883_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0274523.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            11287..12054
                     /locus_tag="VW883_001396"
     CDS             11287..12054
                     /locus_tag="VW883_001396"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0274524.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            12066..13250
                     /locus_tag="VW883_001397"
     CDS             12066..13250
                     /locus_tag="VW883_001397"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0274525.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNLQAITKKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            13247..15118
                     /locus_tag="VW883_001398"
     CDS             13247..15118
                     /locus_tag="VW883_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0274526.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(15261..16445)
                     /gene="mntE"
                     /locus_tag="VW883_001399"
     CDS             complement(15261..16445)
                     /gene="mntE"
                     /locus_tag="VW883_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0274527.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSDIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            16749..19445
                     /locus_tag="VW883_001400"
     CDS             16749..19445
                     /locus_tag="VW883_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0274528.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVILANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            19458..20249
                     /gene="yghU"
                     /locus_tag="VW883_001401"
     CDS             19458..20249
                     /gene="yghU"
                     /locus_tag="VW883_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0274529.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            20365..20775
                     /locus_tag="VW883_001402"
     CDS             20365..20775
                     /locus_tag="VW883_001402"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0274530.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            20787..22382
                     /locus_tag="VW883_001403"
     CDS             20787..22382
                     /locus_tag="VW883_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274531.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            22549..22713
                     /locus_tag="VW883_001404"
     CDS             22549..22713
                     /locus_tag="VW883_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0274532.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
BASE COUNT         6792 a         4322 c         5274 g         6357 t
ORIGIN      
        1 gtgactgctg aaaatatccg gcaatctgtg aagagtcttg agacagacac gcagaacaag
       61 ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ctggctctat ccgtcaggaa
      121 atcctgaacg caaccaagga taaagcagat aagactttag ttgtatctga agctgggaaa
      181 ttgcgtgaag aattttcaaa aatgaaggtg ggaggccgga atctatggat aaaatccaag
      241 acggttggag ctgtaattga aaaattacct gaaaaccacg tcacaggtca aaaagaatgc
      301 tataggctag agaacaactc tactttaacg ttcaaccttg aaccagattt cagctcaagg
      361 ttgtatcaaa aagttacttt tagcgcttgg atcaagtacg aaaatgtagt ccaaggtcga
      421 aatttttgga atgtatttaa ttgcttcaaa cattatcttt ttagaaaaaa tagtgagacc
      481 ggagtacaga gtggtccaga ttatgctacg cttggtatgt ataaaggttc ggcagattgg
      541 aaatatatta cattcactta tgactactct gaaaaaacaa attttgatca attgaagaca
      601 tcattgcgat tcaatcttga aggtgctaca agcggtacag cttgggtaac aggaatcaag
      661 gttgaaatcg gtagtgtggc gacggattgg agccctgcgc ctgaggacgc tgatggtctc
      721 atcactgagg ctaaggctac ctttgagcgg acagctcagg gcttgcgaac cgacttatca
      781 gctattcagg aatatgtaaa taaagacggt cagcgacagg aagccctaca gcgctatact
      841 cgtgaggaga gcacgagaca agcgacagca gtccgtgagc tggtcaatcg tgatttcgtt
      901 ggtaaggtta cttatcaaga agatgttaag ggtatcaatc agaggattga agctgttaaa
      961 actagtgcga ataaagacat cgctagtcaa atcgctagct atcgtcaatc tgtagatggt
     1021 aagttcacgg atatttcaag tcagataact acttataagc aagatgtggg cggtcaaatc
     1081 agtggccttt caaatagact tacaagcagt gaacaaggaa ccactactca gatttcaaat
     1141 ctttcaaatc ggataaacag taacaaacaa ggcacagata atcagatttc aaatttaaag
     1201 actcaggtcg ctacaaacaa ggataatgct gaacgacaaa tgggtagaat atctgatcag
     1261 gtttctgcaa acaaagcgaa tgctgatagt caatttgcga atgtgaccaa tcaactagtg
     1321 cgaaaagtag agactactga cttccagcgt gttaaggaaa ccagtaaact ttacgagcgg
     1381 attttgggca atactgaaaa tggaattgcg gataaggttg ctcgcatggc tctgaccaat
     1441 caactatttc aggttgaggt tgggaaatat agtgtaagcg gccctaacct cattaagaat
     1501 agtgatttta aaaatgctac gaatgaatgg ggctcaactc aaaatttagg aagattggtt
     1561 aagcatagct tttatcacaa cgggcagaaa gaccttatgc gtttaagtaa tgcaactaaa
     1621 aacgaaaact ttttgtatag tcaccgtttt aatcttgaac gaaatactga ctatgtactg
     1681 aattttagag gatttaacaa cagtgctcta gcaagctatg atgtttatat tttgggacga
     1741 agagcaggcg agagcgatgg attcacaatc gttaagaaag ttgttagcag caagaaacta
     1801 tctacctcta gatgcgaaga tgtttcagta acttttaatt ccggagaaat ggataatgct
     1861 tacattcgtt ttgataacaa tggctcatca tcaggaacag ctgatttgta tattacagaa
     1921 gttgacttgt acaaaggtta taaacctaga acatggcaac cacatccaga agatgcagtc
     1981 gcagatgcga ataagaagct tgaagcaacg caaacaaaaa tgactcaact agctggctca
     2041 tgggtagttg aaaacatcaa ctcggctgga gatatcatct ctggaatcaa tcttggcgcc
     2101 aatggacata accgcttagt tgggaaattg acccacatca ctggagagac cctgattgac
     2161 agagcagtca tcaagtctgc catggttgat aagctcaaaa cggccaattt tgaagctggt
     2221 tcggtcacga ctacgatatt agaagctgaa gcggtaactg ctgagaagtt gaaagttgac
     2281 gatgcgctta ttagaaaatt aactgcaaaa gatgctttta ttgaccgact gacatctaaa
     2341 cgtatcttct ctactaaggt tgagtccgtc atttctagct caaccttcct agaagcctat
     2401 caaggccgaa ttggtggatt cacacttggt caatttgacc agggtggcgg tcgctggatt
     2461 tcaggtgtca atcagttctc tgttggtatg gggaatggtg ccgggcatgg agtccggaca
     2521 gccttctggg cgaactgggg aaataattgg aactatgccg gacctaaagc atggaacgtc
     2581 aatactgatg ggaaaatgta ctgtaggaat gaagtcggtt tttatgatca agtggatttt
     2641 tcgaattcat cgagagcaaa cttctatggg aatactactt tttctcgttc tcctgtgttt
     2701 tcaaatggta tcgaacttgg aagtaaagat gtgcttggtg atggttggaa tcccaaaggc
     2761 ggaaggaatg cggttgtttg gtggaatcag gtcggtagcg gtagcgtgaa gtattggatg
     2821 gaacaaaaat cagacagacg cttaaaagag aacatcacag atacagctgt gaaagccttg
     2881 gacaaaatca acagattaag aatggttgca tttgatttca tcgaaaataa aaaacatgag
     2941 gagattggtc taatagctca agaggctgaa accatcgttc caaaaattgt ctcacgagat
     3001 cctgagaatc cagatggcta tctgcatatc gactataccg ctttagttcc ttacttaatc
     3061 aaggctattc aagaattaaa tcaaaaaata gaaaaaatgg agaaaacaat agcatgaata
     3121 acaacatgtt gaccaatatc gcacttaaag caatttagga acttgctctt gaaaatagaa
     3181 aacgaacaca cagattggag aacttagaaa atgaacacag aacagcttaa ccaagcctta
     3241 caaatgacaa ttagtgaaat gtcaacaact tcaacaaatt cgatgattac aagtaatatc
     3301 ttgagtattc agttgaatga gcaaagggaa gagaatcaaa gacttcaagc acgagtggat
     3361 gagctggaag ctctgcttga tgaacaaact aaaccagcag acaaaggaga atagacatgg
     3421 cagaaacaat tcaaaacaca gataacttac tagaccttac aaaaatcaca gaaccatttg
     3481 atcttgcgag cgctttgcgc tacatgaaag aaaatggaga gttcattcgt tgcaagaatg
     3541 taagcgatga cttctatatg tatcgtgacg ttcaaaaacg tcctgtgatc gtaaatggcc
     3601 gtcgccaatt caaggatgtt gaaaccgttt gggcattcaa ccagtggggt ggtacaatcg
     3661 caacaatcaa cgtagccgtt ctgttgaatc atgaattcta tatcatgaaa tttgatgcag
     3721 agggcaatcc tgactggacg gttccaacgg tagaacctaa agaataggag gttgtatgcc
     3781 aattgaagaa gctgaaaaaa tcgctcaaag tcaggtagct tgggcgattt tgtttatctt
     3841 gctttttttt attatcattc gatatcttat caagacttcg gacaagcgag agaagaagat
     3901 tatggatttg cacgagcaat caaaggccga ctctaataga cgagaagagc gtttgatgac
     3961 tcacctagaa aagaccacta cagaattaac cacaatcact cacacggtcg gagacattca
     4021 aaaagaaatg gttcgcatga acgaccgcat ggaagaaatc gaaaaaggag aataacaaat
     4081 gcaacaaatt actgaaatca tcattgcttt tgcgacaggc tttttagcag tagcagtagg
     4141 cggtattgta aaagcagtaa aagattatct tttgcgtaaa ggcggagaga aagcggtgat
     4201 catcgctgaa attctagcta aaaatgcagt tcatgccgtt gagcaagtag ctgctgaaac
     4261 tggctacaag ggagatgaaa aactggcaca ggctcgcgct aaagtccgtg ctgagcttac
     4321 aaaatacaat attagcatga ctgacaaaga cttagacacc ttcgtagagt cagcagtgaa
     4381 gcagatgaat gacgcatgga aaggacgata gggaatggat atcgatagaa acagactacg
     4441 tacaggcttg ccccaggttg gggtgcagcc ttatcgacaa gtacacgccc actcaacagg
     4501 caaccgtaac tcaaccgctc aaaatgaagc ggattatcac tatagaaagg accctgaact
     4561 agggttcttt tcacatgttg tcggaaacgg ccgtgtcatg caagtaggtc ctgtgaacaa
     4621 cggaagttgg gatgttgggg gcggttggaa tactgagacc tatgcagcgg ttgaactgat
     4681 tgaaagccat tcaactaaag aagagttcat ggctgactat cgcctctata tcgaattgct
     4741 acgcaatcta gcggacgaag caggcttgcc gaagactctt gatacagacg acttggcagg
     4801 tatcaagacg catgaatact gtaccaataa ccaaccaaac aaccactcag accatgtgga
     4861 tccatatcca tatcttgcta aatggggcat tagccgtgaa cagtttaagc aagacatcga
     4921 aaacggcttg agcgctgcaa caggctggca gaaaaatggc actggctact ggtacgtaca
     4981 ctcagacggc tcttatccaa aagataagtt tgagaaaatc aacggtacct ggtattattt
     5041 cgatggctca ggctatatgc ttgcagaccg ctggaagaag cacacagacg gtaattggta
     5101 ctactttgac caatcaggcg aaatggccac aggctggaag aaaatcgctg acaagtggta
     5161 ctatttcgac gtagaaggtg ccatgaagac aggttgggtc aagtacaagg acacttggta
     5221 ctacttagac gctaaagaag gtgctatggt atcaaatgct tttatccagt cagcagacgg
     5281 aacaggctgg tactacctca aaccagacgg aacactggca gacaagccag aattcacagt
     5341 agagccagat ggcttgatta cagttaaata aatagaaagg aaactttcta aattgttctt
     5401 tcaccgcagg ctcaggcttg cggttttttt gttttaaaaa aggggcaaaa aaggggcaaa
     5461 agtgtcgtaa atctctgtaa aatgatgtaa aaacatttat ttaaaagctc aaaatatagc
     5521 tgttttaaaa ggtattgtaa gatatagtaa aacgatgtaa aggtattttt aaatgcggat
     5581 gaattataaa accacgaatc ctatgtgact cgtggttctt ttttataaac tggtagagtg
     5641 ttttggttgt actttttgtt cagggtcaat gtagttgata gcgttgttga cagcagttgg
     5701 agcttctccg aggcctgtcg caatcagatc aatttttccg tcatagtagc agcagtcacc
     5761 gatagcatag atacctgctt ggctggattc ttgtttgctg ttgacgataa tcttgtgacg
     5821 gttgaggtcg agcccccagt ttttaaggtt accgacagaa gatttgaaac catagttgac
     5881 aaagaggtgg tctaggtcaa tggtttcagt ttcatcagat ttgacttttg tgatttcaag
     5941 tttatcaagt gtttttccat ttccaaggag ttggccaggg gcgaatggtg tcttgatggt
     6001 tacagatgat tcttgcaagg cttgaacact gtgttccaag gcacggaaat tatctctgcg
     6061 gtgaacaagg gtagttggtg cgattttttc aaaagccaaa gcccaatcca cagccgagtc
     6121 tcccccacca agaatcgtca ctttcttacc agcgtattgc tgaatgttag aaacgtggta
     6181 gtggatattt tcatagccct caaccccttc aagttccagc ggacgtggtt tgaaggcacc
     6241 gccacccata gcgatgataa ctgttttagt caggtgactt cctttagaag ttgtgatggc
     6301 aaattcttct tgtttgtcaa tctcaagaac cgtttcattg agatgaatag gggtatcaaa
     6361 tccatttagc tgttcaatca agcggttagt caactcttct ccagtcaggt ttgggaagcc
     6421 tggtacgtct aggatttcct tttcagggta gagaatagca ggttgtccac ctagctgggg
     6481 aagagagtcg atgatttgaa ccttggcttg gcgtaggtgg gcataaaagg ctgcaaaaag
     6541 cccgacagga ccaccaccca caatggtaat atcatagagt tgagacatag tttctccttt
     6601 gttttttcta gtcagtttat tttatcatat ttttgttcaa tgtaaaatgg actaggatag
     6661 ggaaaaaaat gcccgaaaat ggtataatag gacgaaagtg ttttgatagg gaggatatca
     6721 gggatgaatt ttcaacaatt atccaatctg caatattgga ccagtttgtt tgcaagtcca
     6781 tggacgatag ctatcaatct gattgatatt ttgattgttg cttatatttt ataccatttt
     6841 acaaaagcta ttgcaggaac caagattatg attttggtac gtggagtttt ggtatttatt
     6901 ttagctcaaa tccttgcaaa tatgattggt ttgactacga tttcttggtt aatcaatcaa
     6961 attattactt atggggttat tgcggcggtt gttatcttct ctccagagat tcggactggt
     7021 ttggaacgtt tgggaagagc gacagatttc ttttccaatg cccctattag tgctgaggaa
     7081 cagatgattc gtgcctttgt taagtctgtt gaatacatga gtcctcgtaa aatcggggcc
     7141 ttggttgcta ttcagcgtgt acgtaccttg caggagtata tttcgacagg aattcccttg
     7201 gatgctaaga tttctgcaga acttctcatt aacattttta ttcccaacac tcccctacat
     7261 gacggtgcgg tgattatcaa agaagaacgt atcgctgtga cgtctgccta tctgcccttg
     7321 acaaaaaaca cagggatttc caaggaattt gggaccagac accgggcggc tatcggttta
     7381 tcagaagtct cagatgcctt gacttttgtc gtatcagagg aaacgggagg aatttcgata
     7441 acctataatg gaaggtttaa gcacaaccta acacttgatg aatttgaaac agaattacgt
     7501 gaaatcttac ttccaaaaga ggaagtgggt cttagtttta aagaacgatt gctaggagga
     7561 tggaaacatg aaaaaaaata gtttatatat catatcctca ctcttttttg cttgtgtctt
     7621 atttgtctat gctacggcga cgaattttca aaacagtacc agtgctaggc aggtaaaaac
     7681 ggaaacctat actaatacag taacaaatgt ccctattgac atacgctata atagtgataa
     7741 gtattttatt agcggttttg cttcagaagt atcagtggtc ttgactggtg caaatcgcct
     7801 atcgctagct agtgaaatgc aagaaagtac acgtaaattc aaggttactg ctgacctaac
     7861 agatgccggt gttggaacga ttgaagttcc tttgagcatt gaagatttac ccaatgggct
     7921 gaccgctgtg gcgactccgc aaaaaattac agtcaagatt ggtaagaagg ctcagaagga
     7981 taaggtaaag attgtaccag agattgaccc tagtcaaatt gatagtcggg tgcaaattga
     8041 aaatgtcatg gtgtcagata aagaagtgtc gattacgagt gaccaagaga cattggatag
     8101 aattgataag attatcgctg tcttgccaac tagcgaacgt ataacaggta attacagtgg
     8161 ttcagtacct ttgcaggcaa tcgaccgcaa tggtgttgtc ttaccggcag ttatcactcc
     8221 gtttgataca ataatgaagg tgactacaaa accagtagca ccaagttcaa gcacatcaaa
     8281 ttcaagtaca agcagttcat cggagacatc ttcgtcaacg aaagcaacta gttcaaaaac
     8341 gaattaaaaa tagaaaagga ttttataaca atgggtaaat attttgggac tgatggagtc
     8401 cgtggagaag ctaacctaga actaacacca gaattagcct ttaaactagg acgttttgga
     8461 ggctatgttc ttagtcaaca tgaaacggaa gcgccgaaag tctttgtagg acgtgacaca
     8521 cgtatttcag gggaaatgct ggaatcggcc ttggtggcag gtctcctttc agtagggatt
     8581 cacgtataca aacttggtgt ccttgcaaca ccagcagtag cttacttggt tgaaactgaa
     8641 ggagcaagtg ccggtgtcat gatttctgct agccacaacc cagcccttga taacggaatc
     8701 aagttctttg gcggtgatgg cttcaaacta gatgatgaaa aagaagcaga aattgaagcc
     8761 ttgctagatg ctgaggaaga cactcttcct cgtccaagtg cagaaggctt aggaattttg
     8821 gtagattatc cagaaggctt gcgtaagtat gaaggatacc ttgtttcaac tggaactcct
     8881 cttgatggaa tgaaggttgc cttggataca gctaatggag cagcttctac cagtgcccgt
     8941 caaatctttg cagaccttgg tgcccaattg acggttatcg gggaaacacc agacggtctt
     9001 aacatcaacc ttaatgttgg ttcaacacat ccagaagccc ttcaagaagt ggtcaaagaa
     9061 agtgggtcag ctattggttt ggcctttgat ggagacagtg accgcttgat tgctgttgat
     9121 gagaatggtg acatcgtcga tggtgacaag attatgtata tcatcggaaa atacctttct
     9181 gaaaaaggac aattggctca aaatacaatt gtgacaactg ttatgtctaa ccttggtttc
     9241 cacaaggcct tgaatcgcga aggtattaac aaggcagtta ctgcagttgg tgaccgctac
     9301 gttgttgaag aaatgagaaa atcaggctac aaccttggtg gtgaacagtc tggtcacgtt
     9361 atcttgatgg attacaatac cacaggtgat ggtcaattat cagcagttca attgactaaa
     9421 atcatgaagg aaactggtaa gagcttatca gagttggcgg cagaagtaac gatttatcca
     9481 caaaaattag ttaatatccg agtggaaaac gtcatgaagg aaaaggccat ggaagtgcca
     9541 gctatcaagg ccatcatcga gaagatggaa gaagaaatgg cggggaacgg ccgtatcctt
     9601 gttcgtccaa gtggaacaga gcccctcttg cgtgttatgg cagaagcgcc tacaatagaa
     9661 gaagtggact actatgttga taccatcaca gatgtagttc gtgctgaaat tgggattgac
     9721 taaatcctag aaaactagat gaaaataaaa aattatggta caatagctta taatattgta
     9781 gccgatggag aaagacatga atcttaaacg tgaacaagaa tttgttagtc agtatcattt
     9841 tgatgcgcgt aattttgaat gggaaaatga aaatggagct cctgaaacca aggtggatgt
     9901 gaatttccaa ttgctccaac atgaccaaga aaatcaagtg acttccttga ttgtcatctt
     9961 gagctttatg attgtatttg ataagtttgt cattagtgga acaatctcac aagtaaacca
    10021 tatcgatggc cgtattgtca atgaaccaag tgaattgaac caagaagagg tggaaacctt
    10081 ggctcgtcca tgtttgaaca tgctcaatcg tttgacttac gaagtgactg aaattgcatt
    10141 agacttacca ggaattaatt tggagttcta atatgaaatt agctgttttc acagattcct
    10201 ctgcttatct cagtgaagag accttgcaaa gagaagactt gtttgtcttg gatattcctg
    10261 tcaatattga tggtgaggaa tatgtcgaag gcatcaatct gtctgctgag gaattttacc
    10321 aaaaaatggc tcaggcttct gaattgccta agaccagtca accaagtatt gccaagttag
    10381 atgagatctt aacttcgctc aaagaacaag gctatacaca tgccttgggg cttttcctat
    10441 cttctggaat ttcaggtttt taccaaaata tccagtatat ggtcgatgac tatgagggct
    10501 taaccattgc tttcccagac actttgatta caagtgctcc cctaggcatc atggttgaaa
    10561 gcgtctttaa ttggcgtgat cagggcgatg attttgccag cattcaggat aagctagcca
    10621 ttcaaatcag ccgtacgtca gcctttatca tggtagatga cttggatcat ttggtaaaag
    10681 gtggacgcct ttcaaatggg gctgccattt tgggcaattt gcttagcatt aagccaatcc
    10741 tttattttaa cgatcaaggt gtgattgaag tttacgaaaa agttcgtact gaaaagaagg
    10801 ccaccaaacg cttaattgaa attatcaagg aaacaacggc ttcaggtcaa taccgggtca
    10861 ttgtcattca tgggaatgct cctgaaaagg ctgaagaatt gcgtcagcat ttgcttgatt
    10921 ttggcttggg ttcggatgtt tcacttgcta catttggtag tgtcattgga acgcacctag
    10981 gagcaggaag tattgctctg ggttatattc cagtgattta gtaggcactt ctaggctagt
    11041 taatcttagc aattgaacac ggactacctg cctcttgaaa aaagatgtct gtcttgcctt
    11101 tcgtggaaag tcagtgccat tccctatttt tcatgggtgg ctaagatcct ttgtattttg
    11161 ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaagg agtagacact
    11221 tcttgatcag aattcctatt ttcactttgt gttcttacag gctttgtatc ttagacagga
    11281 gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg tcaagctgct
    11341 tgccagatgg tcttgcctga ttcagatttg gacttggtag cagttttgga tccttttgag
    11401 tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt agctggtttt
    11461 gaagcggatg tctgggtaga ttttactact ccagctgttg cctacgaaaa tacacgtttt
    11521 gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag tgaagaaatt
    11581 gcagagctaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt
    11641 gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata tttcccaaat
    11701 gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg aacagccatt
    11761 aaaacagctg agttgatggc agaggttcga gagtccattc agcaaggcgc agcagatgag
    11821 gaagagctga ttgctggtgc tcgtggtgct gactttgatg gtatgcgcat ccactcagtt
    11881 cgtttgccag gcttggtagc tcatcaagaa gtcatctttg gcaatcaggg agaagggttg
    11941 accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa tttgggaatt
    12001 aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt atgagattaa
    12061 cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt aaagaagcag
    12121 gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat agccctatcc
    12181 acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt tttccgcgaa
    12241 cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat gaggagtatg
    12301 aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc agtgcggttt
    12361 cctttgtgcg ctcgctagaa gaagacctca aacgccgtga tttcacagtc aacgcctttg
    12421 ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat ttggaaaagc
    12481 aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct ttacggatta
    12541 tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgagccagaa acatttaaag
    12601 ctatgaagac cttgacgccg cttttggaga aaatttctgt agagcgtacc ttcgtcgagt
    12661 ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg attgagagtc
    12721 aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac agactgtttg
    12781 atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct ttactatggg
    12841 ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca cgccagtttg
    12901 ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga gaattgagca
    12961 agcgagattg ttatcgcttt gatatagatt tgcttttaca ggctgaaaat cttcgtcaag
    13021 ctcaaggaaa agaagtcaac ctacaagcca tcacaaaaaa ataccaaagc ttgactatcc
    13081 atgacaagaa agagattcag attaatggcg atattttgat caaggaatat ggctatcagc
    13141 caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc gatggagaat
    13201 tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga gtgattttat
    13261 cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata tttcctttat
    13321 tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca agaccaccct
    13381 tttggacgtc ctttctggtg tttctggatt tgatggggat gtcagtcctt tttcagctaa
    13441 aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata gaaagacagt
    13501 tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt
    13561 gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca tggcagagat
    13621 ggactctctc caagcttggg aaattgagag tcaggtcaag accgttctta gcaaattggg
    13681 cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa gacgggtaca
    13741 gttggcacaa gtcttacttg gcaaccacga ccttttgctt ttggatgagc cgaccaacca
    13801 tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta agaagaccgt
    13861 cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga ttttcgagtt
    13921 ggagcgagca ggcttgacag aatatcaggg caattaccag gactatgttc gccttaaggc
    13981 agaacaggac gagcgcgatg cagctctact tcataaaaaa gaacaactct acaaacaaga
    14041 actggcctgg atgcgcagac aaccgcaggc acgtgcgacc aagcaacaag cccgtatcaa
    14101 tcgattccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag acttgaccat
    14161 gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg tttcctttgc
    14221 ctatgaaaac aagcctattt tgcaagattt taatctcttg gtgcaggcca aagaccgtat
    14281 cggaatcgtt ggggacaatg gtgttggaaa atcaaccctg ctcaacttga ttgcaggaag
    14341 tcttgagcca actaaaggac aagttgtgat tggggaaact gttcgcatcg cctatttctc
    14401 tcagcaaatt gagggtttgg atgaaagcaa gagagttatc aattacctgc aggaagtggc
    14461 agaggaggtc aagaccagtg gcggttctac gacttcgatt gctgagttgc tggagcaatt
    14521 cctcttccca cgttcgacgc atgggacctt gattgagaag ttgtcagggg gtgagaaaaa
    14581 acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt tagacgagcc
    14641 aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc aaggttttgc
    14701 aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag cgaccaagat
    14761 tctcgctttt gaggatggca agattcgtcc tttctttggt cattacaccg actatcttga
    14821 tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggccgaaa aggaaaaagt
    14881 ggtcaaggtt cgagaagaca agaaacgcat gacctaccaa gaaaagcagg agtgggcaag
    14941 tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag aggaaatgca
    15001 ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg atgagaaaaa
    15061 tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg atagttaaga
    15121 ctattcgaaa atcaaagtgc aaactatgtc ggcttcacat tgccgactca agtacagcct
    15181 gtgaccggct tcctaatttg cactttgatt tttattgagt ataaaagaat agaaaaatcc
    15241 cgtctcatga aaggatttct ctattctttt ttggtttctt gatgaaagat attttgccag
    15301 gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata gcagatgagt
    15361 ttggtttttt gactgatgga agtaatttga atgtccttga tatcagaatt taactctttt
    15421 ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata gacaaaatca
    15481 tcagtcaaga gttcttctag ttggtttcct tggtcaatca attgttcacg cataagcaat
    15541 tttttataga cattgtctaa aatttcatcc tcagggatag gtgctggttc gatatggaca
    15601 tcggtatcaa agacgccaaa acgctcctcc agcatagact cgacctgatc cgcgatttca
    15661 tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag gtagatgttg
    15721 ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat ttccatgata
    15781 gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact aaaggaagac
    15841 tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat agcaaccagt
    15901 ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt tccaagtgag
    15961 gtaacagcgt cagaaagatt gtccttagca gctgccttca gcgccttgga gttggatttc
    16021 ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga aatgattcct
    16081 agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt ttgaatggta
    16141 tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa gcttgccaaa
    16201 tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg cgccatccga
    16261 atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa accatcggcc
    16321 accaaactgg atgaatgaag gagatgacca gctgctaatt tggctgcaga caagatcaaa
    16381 taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga gatagattgc
    16441 ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt ttcaaggaaa
    16501 aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta taatggtact
    16561 actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat tttatgctga
    16621 aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa caggtctctt
    16681 tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca atgtcaagga
    16741 ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc cctgaagagg
    16801 tcttgcaggc tgtggatgcg accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc
    16861 ttgccgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat
    16921 tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca atcttgtcag
    16981 tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct gtggttatca
    17041 tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt gaagccctca
    17101 aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca gagattgact
    17161 ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg
    17221 acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg acaggtgaat
    17281 ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt attggtgacc
    17341 gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg ggtgttgttg
    17401 tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa gatgcggatg
    17461 agactgatac accactcaaa caaaatttga acaacctttc taaggtcttg acctatgcta
    17521 tcttggtcat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg aaaaatccac
    17581 ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa ggacttcctg
    17641 ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga cattccatcg
    17701 ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct tctgataaga
    17761 ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat gcggttctac
    17821 atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt tcagttatct
    17881 tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca accgaaacag
    17941 cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta gagaaatatc
    18001 ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca gttcacccat
    18061 tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt
    18121 gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt acaaatctca
    18181 ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca ggtgcttata
    18241 agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat gatttaattt
    18301 ttactggttt gattgggatg attgatcctg aacgtcctga agctgctgag gctgttcgtg
    18361 tggctaagga agctggaatt cgtccaatta tgattacagg tgaccaccaa gacaccgcag
    18421 aagctattgc caaacgtttg ggaatcattg acgcaaacga tacagaagac cacgttttaa
    18481 ctggtgctga gctcaacgaa ttatctgatg aagactttga aaaagttgtt ggtcaatact
    18541 ctgtttatgc ccgtgtgtct ccagagcaca aggttcgtat cgtcaaggct tggcaaaaac
    18601 aaggtaaggt cgttgccatg acaggtgacg gtgtcaatga tgccccagct ctgaaaacag
    18661 cagacatcgg tatcggtatg ggaatcactg gtacagaggt ttctaagggg gcttctgata
    18721 tgattcttgc agatgataac tttgcgacta ttatcgtcgc agtggaagaa ggacgtaagg
    18781 tcttctcaaa tattcaaaag actattcagt acctactttc tgccaatact gctgaagtat
    18841 taaccatctt cctatcaacc ttgtttggtt gggacgtctt gcagccagtt catcttttgt
    18901 ggattaactt ggtaacggat accttcccag caattgcact aggtgttgaa cctgcggaac
    18961 ctggtgtcat gaatcataaa ccacgtggac gcaaggcaag cttcttctca ggtggtgttt
    19021 tgagttctat catttatcaa ggtgtactcc aagcagctct tgttatgagt gtttatggcc
    19081 ttgcgattgc ttacccagtt catgtgggtg acaatcatgc tattcatgca gatgccctaa
    19141 cgatggcctt tgcaaccctt ggtttgattc agctcttcca tgcctacaat gtcaagtctg
    19201 tctaccaatc catcttgaca gttggcccat tcaagtctaa gacctttaac tggtccatct
    19261 tggtatcctt tatccttctc atggcaacaa tcgttgtaga accgcttgaa ggaatcttcc
    19321 acgtaaccaa actagacttg tcacaatggg gaattgttat ggctggaagc ttctcaatga
    19381 ttatcatcgt cgaaatcgtt aagtttattc aacgcaaact cggttttgac aagaatgcga
    19441 tttaagggag gtttcggatg tcagcatatc aattaccgac cgtatggcag gatgaagcta
    19501 gtaatcaagg agcttttacg gggttaaaca gaccaacagc aggtgcccgt ttcgaacaaa
    19561 acttgccaaa aggagaacaa gcttttcagc tttattcact gggaacacca aatggtgtga
    19621 aggttactat cttattggaa gaattactag aagctggttt taaggaagcg gcttacgact
    19681 tgtataagat tgctatcatg gatggggatc aattcggctc agactttgtg aagctcaatc
    19741 caaattccaa gattccagcc ttattggacc agtcaggtac tgaaaacgta agagtctttg
    19801 agtctgctca tattcttctt taccttgctg agaaatttgg agccttttta ccaagtaatc
    19861 ctgtggaaaa ggtagaagtt ttgaattggc tattctggca agcaggtgca gcaccttttc
    19921 taggtggggg atttggacat ttcttcaatt atgctcctga aaaattggaa tatcctatta
    19981 accgttttac gatggaagtg aaacgccagt tggatttatt ggataaggaa ttggctcaga
    20041 aaccttatat tgcaggcaat gactatacga ttgcagatat tgctatctgg tcttggtatg
    20101 gacagttagt tcaaggaaat ctttaccaag gttctgcaaa atttttggat gcctcaagtt
    20161 atcaaaatct agtaaaatgg gcagaaaaaa ttgccaatcg tccagctgtt aagcgtggat
    20221 tggaagtaac ttatacagaa attaaatagc aaaaaagtca tcttcggatg gctttttgct
    20281 acagttgagg gaaagggttt gcagttatcg gcttttgtgc tataattgct ataatatagt
    20341 aaaaagcaag aggagtgtga ggaagtggaa aagaaaattg tgaaggatat cttattttta
    20401 tctcaagtgt ctcagccggc aagtcaggag gacctttatc ttgccagaga tttgcaggat
    20461 acactcttag caaatcgtga tacctgtgtt ggtctagctg ccaatatgat tggggtgcag
    20521 aagcgcgtga ttatctttaa tcttggcttg gttcccgtgg tcatgtttaa cccagtgctt
    20581 ctgtcctttg aaggatccta tgaggcagaa gaaggctgtt tgtccttggt aggtgtgaga
    20641 tcaactaagc gttatgaaac cacaaggctt gcctatcgtg acagcaagtg gcaggaacag
    20701 accattacct tgacaggctt cccagctcag atttgccagc atgagctgga tcacttggaa
    20761 ggacgaatca tttaggagga aagcaaatga aacgaatagt ctttgaactt atttttatcg
    20821 caacgacctg gtatatcttt ttaccgcccc ttaacctgac cagctgggaa tttctcttct
    20881 tcctctgtgg gcatttgtta gttgtggcaa tcttatttgg ctttggcaag gggataaacc
    20941 ttgtcaaaac ggttcatgtg cgccacggta aggcggaagc tgccttaaat cttgagggtt
    21001 tcaaaatcaa tcggttaggg aaaattctgt tagcttcgat tggaggaatt cttctcttgg
    21061 cagctttggt ttccttggta acttccagca tgtttcaggc taaaaattat gccaatgtag
    21121 tcacggttac ggaaaaagac tttactgaat ttcctaggag tgacaccagt aaggttccta
    21181 tcctagatag aagtactgct gaaaaaattg gagaccgcta cttgggttcc ctaaccgata
    21241 aggtgtcgca atacgtagcg gcagatacct atacccaatt gacaattgat gggaaacctt
    21301 atcgggtcac accactagaa tatgcagacc ctatcaaatg gtttaacaat caagccaagg
    21361 gaatcggtga gtatatcaag gtggacatgg taactggaaa tgcggatttg gtggacttga
    21421 agacaccaat caagtattca gactcggagt attttaaccg tgatgtcaaa cgtcacctgc
    21481 gcttgaagta cccgactaaa atctttaaaa ctccatcttt tgaggtggac gatgagggca
    21541 atcctttcta tgtagcaacg gtttaccaaa agcaatttgg acttgcggtt cctcgtcctg
    21601 cttcagtcat tatcttggat gctacaaatg gagaaaccaa ggaatacagc ttatcagatg
    21661 ttccagaatg ggtggacagg atctatccag cagaggaaac cattgagcaa atcaactaca
    21721 acggcaagta caaggacggt ttcttgaatg ccatgatttc caagaaaaac gtgacccaga
    21781 ctaccaatgg ctataattac ttgtctatcg gtaatgacat ctatctctac acaggtgtga
    21841 cgtcggctaa tgcggatgag agtaatcttg gtttcatcct tgaaaatatg cgaacaggag
    21901 aaattactaa gtatagcttg gcttctgcga cagaagaatc agcccgtgaa tcagcagaag
    21961 gtgctgttca ggagaaatcc tacaaagcaa ccttcccaat cctcatcaac ctcaatgaca
    22021 agcctctcta catcatgggc ttaaaggaca atgctggctt ggtcaaagag tacgccctgg
    22081 tagacgcagt cgagtaccaa aatgttatcg ttgctactac agtggaagag atgctcagca
    22141 agtatgccaa taaaaacgac cttgaaattg acaatgcaac gacagaaagc atcaagggag
    22201 tagtagcaga cctcaaatca gctgttatca agggagacac tgtctacttc tttaaagttg
    22261 atggcaagat atacaaggta aaggcttcag tatccgatga ccttccttac cttgaaaatg
    22321 gtaaaacctt cgaaggtcaa gtaggaaaag acaattatct caagaccttt aaagtacaat
    22381 aatactcttc gaaaatctct agctctatct gcaacctcaa aacagtgttt tgagcagcct
    22441 gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaaaaagg tttatttaat
    22501 aaatatatgt tataataagg taaattaagc ctaatggagg acaaagaaat gggtttttat
    22561 ttgatggttg cttcaatgct actcggactg ctcgctttga agataggttt ttctcagttc
    22621 aaggagaaaa aagataaatt cttatctatc ttaacaagtt tagctggcac agcccttgtt
    22681 ctcgtggctg tctggttagg atggcccaaa taaatagaaa aacctcggtc aaaccgaggt
    22741 ttttc
//
LOCUS       DAVKXA010000034        22597 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKXA010000034 DAVKXA010000000
VERSION     DAVKXA010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.034"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..2378)
                     /locus_tag="VW883_001405"
     CDS             complement(<1..2378)
                     /locus_tag="VW883_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV0274533.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSKN
                     NLTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSRIKTKYLY
                     GLKEKSEAELTLKTKETKEELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYP
                     TNTYKTIELEIAEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKL
                     EKIKSDIEKTYLYKLDNSTKETPKPRVRRNSPEIKAKGRVKNYEEANIELSKYMTDLY
                     KLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWFAD
                     LLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQPGG
                     QAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVPDG
                     AKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEAKA
                     KLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHLKK
                     EKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLIQN
                     TPQVPEAPKSPEVPKVSDTPKAPDTPQVPEAPKSPEVPKVPEAPKAPDTPQVPEAPKS
                     PEVPKVPDTPKAPDTPQVPEAPKSPEVPKVPDTPKAPDTPQVPEAPKAPDTPQIPEAP
                     APETPAPAPEAPKTGWKQENGMWYFYNTDGSMATGWLEYNGSWYYLNANGAMA"
     gene            complement(2457..2984)
                     /locus_tag="VW883_001406"
     CDS             complement(2457..2984)
                     /locus_tag="VW883_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0274534.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(3067..4398)
                     /gene="hk06"
                     /locus_tag="VW883_001407"
     CDS             complement(3067..4398)
                     /gene="hk06"
                     /locus_tag="VW883_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0274535.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(4395..5048)
                     /gene="rr06"
                     /locus_tag="VW883_001408"
     CDS             complement(4395..5048)
                     /gene="rr06"
                     /locus_tag="VW883_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0274536.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(5369..7801)
                     /locus_tag="VW883_001409"
     CDS             complement(5369..7801)
                     /locus_tag="VW883_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0274537.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7803..8261)
                     /locus_tag="VW883_001410"
     CDS             complement(7803..8261)
                     /locus_tag="VW883_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0274538.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(8384..9109)
                     /locus_tag="VW883_001411"
     CDS             complement(8384..9109)
                     /locus_tag="VW883_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274539.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            complement(9109..10116)
                     /locus_tag="VW883_001412"
     CDS             complement(9109..10116)
                     /locus_tag="VW883_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0274540.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(10155..10913)
                     /locus_tag="VW883_001413"
     CDS             complement(10155..10913)
                     /locus_tag="VW883_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274541.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(10876..11166)
                     /locus_tag="VW883_001414"
     CDS             complement(10876..11166)
                     /locus_tag="VW883_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0274542.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(11237..11339)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(11422..12768)
                     /gene="cbpD"
                     /locus_tag="VW883_001415"
     CDS             complement(11422..12768)
                     /gene="cbpD"
                     /locus_tag="VW883_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0274543.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     gene            complement(12857..13123)
                     /locus_tag="VW883_001416"
     CDS             complement(12857..13123)
                     /locus_tag="VW883_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274544.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(13125..14477)
                     /gene="dnaB"
                     /locus_tag="VW883_001417"
     CDS             complement(13125..14477)
                     /gene="dnaB"
                     /locus_tag="VW883_001417"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0274545.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(14521..14973)
                     /gene="rplI"
                     /locus_tag="VW883_001418"
     CDS             complement(14521..14973)
                     /gene="rplI"
                     /locus_tag="VW883_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0274546.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14970..16943)
                     /locus_tag="VW883_001419"
     CDS             complement(14970..16943)
                     /locus_tag="VW883_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0274547.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(17079..17627)
                     /gene="raiA"
                     /locus_tag="VW883_001420"
     CDS             complement(17079..17627)
                     /gene="raiA"
                     /locus_tag="VW883_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0274548.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(17707..18369)
                     /locus_tag="VW883_001421"
     CDS             complement(17707..18369)
                     /locus_tag="VW883_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0274549.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(18366..19664)
                     /locus_tag="VW883_001422"
     CDS             complement(18366..19664)
                     /locus_tag="VW883_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0274550.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19720..20355
                     /locus_tag="VW883_001423"
     CDS             19720..20355
                     /locus_tag="VW883_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0274551.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            20604..21524
                     /gene="cysK"
                     /locus_tag="VW883_001424"
     CDS             20604..21524
                     /gene="cysK"
                     /locus_tag="VW883_001424"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0274552.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(21721..22119)
                     /locus_tag="VW883_001425"
     CDS             complement(21721..22119)
                     /locus_tag="VW883_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274553.1"
                     /translation="MKSPIPKAPLANNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVVIDLFISYFNPL"
     gene            22110..22418
                     /locus_tag="VW883_001426"
                     /pseudo
     CDS             22110..22418
                     /locus_tag="VW883_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6582 a         5071 c         3809 g         7135 t
ORIGIN      
        1 gccatagcac cattagcgtt gagatagtac catgagccat tgtattctag ccagcctgtt
       61 gccattgaac catcagtatt gtagaagtac cacataccgt tttcttgttt ccagcctgtt
      121 tttggagctt ctggagctgg agccggagtt tctggagctg gtgcttccgg aatttgcggt
      181 gtgtctggag cctttggtgc ttctggaacc tgcggtgtgt ccggagcctt tggtgtatct
      241 ggaacctttg gtacctctgg gctctttggt gcttctggaa cttgcggtgt gtccggagcc
      301 tttggtgtat ctggaacctt tggtacctct gggctctttg gtgcttccgg aacttgcggt
      361 gtgtctggag cctttggtgc ttctggaacc tttggtacct ctgggctctt tggtgcttct
      421 ggaacctgcg gtgtgtccgg agcctttggt gtatctgaaa cctttggtac ctctgggctc
      481 tttggtgctt ctggaacctg cggtgtgttc tgaattaagc ctttttggaa tttagtaaca
      541 accgtatcca tgtctgcaaa taccttgtgg actgtattct caatttctac tttggtattt
      601 acattatcaa tttcagaaag tgcttgcttt ttaagtttat caaggtcctt aataagagca
      661 acaatctgat gatgtttttc tttcttcaga tgatgtttct ttatatcatc taaaatcttg
      721 ctcatgtatg ttgctatagc aagtttagct ttttctttct cctgattaat atctggtacg
      781 cttggtttct caccctctgg ttgtggtttt ggctctgggt tttccggctg tggtttaacc
      841 tctggtacca atttcgcttt agcttctttc aatttagaca tggcatcgtt caatttggtt
      901 aattgcattg ccaattcatc cattgtcact gctgtctgtg atagaagctt cttgcttttg
      961 tcaacaactt ctttcgcata agttctagtc tcattatagg cttttccagc ttctcctgtg
     1021 agtttagccc catctggaac agtctttgtt tcatcgtcta gtttgttcaa ggcttcttgg
     1081 aattgacgaa tcaagtcttg taactttttc ttttcagctt cggtcgcctt ttgtcctgga
     1141 ctttgggaag ttgatggagg tgtttgcgtc accggtggta caaccattga accacctgct
     1201 tgtcctcctg gttggggtgc tggttggttt tctttttctc tattttggtg agtcacgata
     1261 agagactcta tttttccttc tgcttccttt cgcaagtctt ctaccgattt tttatctgaa
     1321 gcatcctcta attttgtctt gtattcttcc acaaccttct tagcatccat aagaagatct
     1381 gcaaaccaaa aaacagatgg atccagcttc gttaaacgag ttaccatata ggtagacaga
     1441 gtttctttcg ctttgtctat cgtttcctta agttctctcg aatcgcctac ttgcggagaa
     1501 tttcttcgca ctctagattt tggcgtttct ttggttgagt tatctaattt atacaaatca
     1561 gtcatatatt tagaaagttc aatattagcc tcttcataat ttttgactct gcccttagct
     1621 tttatttccg gagaatttct tcgcactcta ggttttggcg tttctttggt tgagttatct
     1681 aatttataca aatacgtttt ttcaatatct gatttaattt tttctagttt tttaacatta
     1741 cttttagcag cttctacttt agatttagca gcattaattt tctcagtatc ttgaggtatt
     1801 tgaacttgag cttgtgcaaa ctcaagctca agctctgcct tggcgacccc tacttctgct
     1861 tccgcaattt ccagttcgat tgttttgtaa gtattggttg ggtagttacg gcgatcttct
     1921 tctttttgag ctttggcttt tttctcagct tctgctacct tttttcctga tttcaatgta
     1981 tcttttttaa actgctcaaa agctgcggtt aactcttctt ttgtttcttt tgtttttaac
     2041 gtcaactcag cttccgactt ctcttttaat ccatacaaat acttcgtttt aattctgctc
     2101 aactttttgt tgaagtcgac attttgggta tgttgaactt ttttcaaatt tttattgaca
     2161 tccttcaata tactttgtag atgcgactcg acttcatcag catacttctt cgatatatct
     2221 tgcccactag atgtaaccgt gaggttattc ttactcctaa ccccttctgc atggactact
     2281 cctcctaaga acaagctggc aactactaca ctagctactc caatactaaa tttacgaatt
     2341 gaataatgta cttttctttc gctttttgat gcaaacatgt ttatttcctt ctatattttt
     2401 tctttaacct tactatatca cttcaatatg aactgtatat gagtcgaatt ttgtatttat
     2461 ctctttatgc ttccatttgg gattataact tcatgtaata gcttttcctc ttcagctatt
     2521 cgtcgataca aaataactgc ataaactgga aaaactaaaa caaaagtcat ataggcatga
     2581 ctcaacaagg tcaagccaat caactcaggt aaaatattta aaaagtaatt agggtgtttt
     2641 actgtcctaa acaagatatg atctacatat ttgtgattat tgacaagcat aagcttcact
     2701 gtccaaatat ctcccaacaa gtgaatcacc aacatcaaca tcagcataga aaaaataagc
     2761 aagactaaac caaccatgcc catgccatca aaaattgtct tgtgcaccat tgcctcaacc
     2821 aagcaagaga gataaaaaac aatatgagcc atagttaatc gttttgtatt ctcaactcca
     2881 aattctttcc cgccattgct aaggattcgt ttctcattct ctatcgaacg ctttaaaaaa
     2941 atcaatcgaa taaagaatgt tactaaaata atcgctaata ccatattagt atcctttctt
     3001 ttatctacac aaagaataac acacttatgt taaccctata tgaactttaa taaaaaacta
     3061 atctgtctac aagctaatct taaattccat accgtgttca taagggagaa aactataatc
     3121 catttgatag ctttctaaaa tattattcac aatgtaaaga cccaaaccgg aactttcatc
     3181 cttatctgtc acgatttgag aatgataaaa tatatcaaat aaatgttcta gttcttggtc
     3241 acttagaggc gcacatgtat ttttgataga gagatagcca tcttgctcgg atatgattac
     3301 gcgcccattt ttatctgaat atttaattgc attactaatc aggtttgtca aaaccttatc
     3361 caatgcccta agactcatga cgactctggt agcatctgtc aattgatttt caattgtaac
     3421 acctattgaa tgagctaatt cttgataacg tgataaaata tctactaaaa ctggcttaac
     3481 agtcaaagtc tcacgacact ctgtccactc ttggaattta gaagactcca gtacttcttc
     3541 caataagtgg ctcatctggt caatcttatt tatactcttt gcaatatatt ttggatgatc
     3601 tttgtaatct ccaatattat gctgcatatt ctctaggata attctaagac tggctaaagg
     3661 ggttttcaac tcatgtgatg ctccgcggac aaaggaaacc ttttgatttt gcaattttac
     3721 aatttgctca ttacgacttt ccaactcata aataaccttc aacaagtgct catacatacc
     3781 attaatctgt tttccaactt caccaacttc atctttccta ctttcatcaa aacgaatatt
     3841 gtcatccaaa tcttgcattt tactagtcac ttctgaaatg taaaaaagag gattgagcaa
     3901 gcgtttagta taaaaataag aaaaaacaaa ggaaaaagca attgtaacca aaaatgtata
     3961 tgggagatac aaaagcaaaa tattctttgc ttctttgtag acatccaccc cgtgaacaaa
     4021 ttgcactgtt acctgtttac catctgctgt actaacagac atatctaaca tcacgatata
     4081 atttgatagc tttccatctt taatatccaa gtcatgcaca agagggagcc gcttatctac
     4141 aatatctctt ttaaggtgag cagatatggt caaggacttt gaataagact ggagtaagct
     4201 tggaatttca tcagatgtct tagtctttaa atactccgta aacactcttg cgctctcatt
     4261 aaacttttcc ccctccagtt gaatataata aaaaggaaag gtcaaataaa tagctatatg
     4321 aatgactaga ccaacaccac ctagaattgc aaaacttctt aaaaaggact tggttaataa
     4381 tttaggattt tttatcataa actaatctta tacccaacat ttttcacagt cacgatacaa
     4441 tctaaagcta attttttgcg aagagtacga atatagacat caacgaccct atcacaaggt
     4501 aaatcagcta catcttttga aatttcttcc aatatctgct ctctacttaa aacttgattt
     4561 ttatgctgaa tcaaacactt tagtaccagt aattcctttg gtttgagatc aatttcttca
     4621 tttttataat gtgctttgta agaggtaaaa tccactgtta catcctgata tcgccaaata
     4681 tcctctatga cgtagtaacg tctgataagc gccttaatac gcttgacaag cagtaccaaa
     4741 gaaaaaggtt ttgtcacatg atcatcagca tagagatcaa atacctgtga ctgagtaatt
     4801 tcatctccca gagcactcaa gacgatgaca ggaatatcgt gcttttgatt gatttctttt
     4861 aacacttcaa aaccactctt cctaggcatc attaaatcca gtaccatgag atggataggg
     4921 agatcttgaa atttttccaa gacctcttgt ccatccttag ccataatgac atgataaccc
     4981 tcttctgtca gaaatgctgc aattccttct ctaatcattt cctcgtcatc tgcaactaaa
     5041 atgttcatct ctctcccttt ctactaccag aactccatac atctatttcc tgtatgctat
     5101 ttgaaaattt cctaccagcc tatcatctat gataatagaa tggatttcat ttatccgcta
     5161 ctttttgtca acaacaacgt caatacaaga aaatcattca tcttgcagct tatactcttc
     5221 gaaaatctct tcaaaccacg tcagctctat ctgcaacctc aaaacagtgt tttgagcaac
     5281 ctgcggctag ctgcctagtt tgctctttga ttttcattga gtttcactcc actgtgactt
     5341 atggtcagat gctggtactt ttattctttt atgcaatatc aaattttaac tggcctgctt
     5401 tgacaccaat cttaagtgtg ctgcctgcca ctaaatctcc cttgagaaga agttctgcca
     5461 acttgtcctc cacttctgtt tgcagggttc tgcgaagtgg gcgagctccc atctctgggt
     5521 catatccttg atttgctaac aatttcagag ctgaagcttg taatttcaag tcaatgcctt
     5581 tttcagccaa acttgccact aaaggcttga ccataatctt caccacttcc tgcatatgat
     5641 cactagatag gctatggaag accaccttct catcaatacg gttgatgaat tccggtctat
     5701 aagctttttt cagttcttca aacatgcgtt tttccatatt ttcctggtca aaacgaatat
     5761 ccttagcccc aaaaccaaca gtcttatcat cacgaagggc agtcgcacct agattcgatg
     5821 tcataatgat aatggtattt gaaaaatcga ccttgcgtcc cttgctatct gtcaagacac
     5881 cgtcatccag aacctgcaag agaacattaa agatatctgg gtgagccttc tctacctcat
     5941 caaagaggag aacggaatag ggtttattgc gaaccttctc tgtcaactcc ccaccttctt
     6001 cgtaacccac atagcctgga ggagctccat ttagacggct ggctgcgaat ttctccatat
     6061 actcactcat atcaaagcgg ataagggctg attcgtcatc aaagagaact tctgccaaag
     6121 ccttggccaa ctcggtctta ccgacacctg tgggtcctag gaacataaag gaaccgatcg
     6181 gacgcttgtg actgcgaatt cctgactgat tacggcgaat ggcacgacta atgcttgaaa
     6241 cagcttgatc ttgaccgatg acacgtttat ggagttctgc ttcaagattt aaatacttct
     6301 tagcatccgt ttgagtcagt ttttgaactg ggattcctga caagcgactc aaggtggtca
     6361 aaatatcaga ctctgtcacc aagtctttgt agacaggtac ttcctcttct tttgcgatta
     6421 gctgggctgc ctgtttccac ttgccatcca tcagggcctt gtcagctgga ctcaaatctg
     6481 aatcgtctgc ttttacatgc tttgccttat tttgcactgt tgctgctgct tcgtccaaga
     6541 ggtcgatagc agagtctggc aagtgacgac tggttaaata acgatgagcc atcttaaccg
     6601 ctgtttcaac cgcttcatct gtgatttgta cacggtgatg tttctcataa gtcgccttca
     6661 aaccttgtaa aatagtcata ctatctgcca cacttggttc ttcaatcgtc actttagcga
     6721 aacgacgaga aagagccgca tctttttcga tatgtttttg atattcttcc tgagtggtgg
     6781 caccaaccgt tctcaaagtt ccacgcgcca aggctggttt caagatattg gccgcatcca
     6841 gagtcgaatc aattccgcta ccagaaccca tgatggtgtg gagttcatcg ataaagagga
     6901 tgacttggcc atcttcttca atatccttga tgatattatt catgcgttct tcaaagtcac
     6961 cacggaagcg tgtccctgca acgacattca tcaaatcaag ttctaacacg cgcatcttag
     7021 ccatttccgc aggcacgtca ccactagcaa tacgctgggc aagaccaagg gccagagctg
     7081 ttttcccgac accagcatcc ccaaccaaga cagggttgtt cttagtctta cggctcaaga
     7141 tttgaatcat acgtgagatt tccttgtccc gaccgatgac tggttctaac ttgccagaac
     7201 gcgcttgctc tgtcaaatca tgcgtatagt cctcgagacc accactagga gtctgcggca
     7261 tgcccatcat attggccata gaattttgct tgtcagctac tgtacgatgg cgttggcgta
     7321 aagccttgag atcttcacga gtccagcctg cacgttcttc taaatttcga cgaagggcag
     7381 caatcttgac ctgatctttc ttgtcttcat aagaaaaacc agccctctcc aagatacgag
     7441 tcgccaaggc attgccatca tgcaaaatcg catagagaac gtgctctgtc cctagtacct
     7501 tagcatggac cactgacgct acatactctg cttcatcaaa aagaacctgc aaacgacggg
     7561 agaacggcaa ttccgtaaag gtttcatcct ggctatagtc cgtttcagtc agttccaaag
     7621 ccacctcttc taaacggtcc atctcatacg gataatcatt taaagttgcc cctgctacac
     7681 tataactgtg attagacatg gcaatcaaca agtgccacga ctctagataa cgagctccaa
     7741 aatgtccagc aaccatgtag gcactttcga tacattcatt caatgctttt gaatagttca
     7801 tcttacttcc cttttctatc tacctcttgt atgacctgac gtagcatgtt tgctcgaaca
     7861 actggagctt cttctcctaa aacgcgatcc aaagctactg attctagcaa attcatctcc
     7921 tgcttggtca tcaattcctg ctcaaccaaa agctggagaa tatcctcata aatttcttga
     7981 ctgactcgct caccaatcga gtaaagcaga tcccggagca tttcatgatg actagaaaac
     8041 tcaatccgtc ctatacgaat gtagcctccg ccaccacgct tactttcaac caagtagcct
     8101 ctactttccg taaagcgtgt cttgatcacg tagttaatct gactaggaac aacctgaaag
     8161 gtatctgcca actgactccg ttgcaactcc acgataccag attgatctaa aatcgccttg
     8221 atgtaggcct caatatgatc cgatgtattt ttaaatctca taacaaaccc acctctctct
     8281 ttaaaccttg accttgtttg actattatac cgaaattttc tcatttttaa aagaaaaagg
     8341 gcgctggtaa aggataatct tcaccaactc cctatttttc tacttattct aagcctaatt
     8401 ctgccaagat ttgacgtttg taggcaatct tttggacttc cttgtcctca tcttcagacc
     8461 aatctagttt aatttctgaa acaatctgcc cagggcgatt tttcaagata tagatgcggt
     8521 cgctgagatt gagggcctcc tcaatactat gcgtgatgat cagagttgtt agctgcaact
     8581 gtttgtgaat ctcaagatac caagcgtgga gttccatctt tgtcatctca tccaaggcgc
     8641 taaaggcctc atctaagaga aagagcttgt gcccaaaaag gtaggtccgg agtaaggcta
     8701 cacgctggcg catcccaccg ctaagttcat gaggatactt gtctcttaca gctgtcagct
     8761 ggaaggtcgc aagaatttta tccgctcggg aaatagcttc tgccttatcc accttttgaa
     8821 tcaagagggg cagaatgata tttccaagca ccgtcttgtg ctccaagagc agatcctttt
     8881 gcaacatata actcacgcgc cccttgggat tttcttcacc atcaaggaca attctccctg
     8941 actgaacttc taaaatccca gcgattagat taaagagggt ggtctttcca acaccacttg
     9001 ggcctaggat ggaaaccact tcgcctgaag tcacctgtag attgatatcc tctaaaatcc
     9061 tctcctgacc ataggcataa ctgacgtgct ctagtctaat ttctgtcatt atttcacaaa
     9121 ttcgttggtg aagcctttgt ctgtcaagtc ttctttaagg ataccatttt ctttatccca
     9181 tttgtagaaa gcattccagc gagctgcgtc aaattgaccc catttttcct tgtcgcttgc
     9241 gtattctttt gacaagtatt tttgagattc gatgacaaag tcacgttttt ccttgagttc
     9301 aggtgcattc ttgatgagaa tatctgcagc ttcttctgga tgttccatgg catattggta
     9361 gccttttttg atggcttgga tgactttgcg agcttcttct ttgttatctt tcagatagtc
     9421 gttgtttgcg atgataactg gtgaatagta gtcaaactcc ttgacatagt ctttcaagta
     9481 catgaagtta gcatctacac cttgagattt agcaaggata ccatcccaac cgtagtaaat
     9541 ccaagcagta tcaaagacgc cattggcaat cggtgtgatt gagtttgagt cgttatttgg
     9601 tactttttca accttctcaa agtctccacc ttgagattct accaaggttt tcaacatagc
     9661 aagttcagtt gggtcattcc atgtcccata tttcttacca accaagtctt ttggactgct
     9721 tacattatca gatttacgag agatgattcc tgatgtattg tgttcaacaa tagctgcaac
     9781 ggcagtgatt cctgctcctt tttccaattt cttagccatg tagtcttgga aatacactgc
     9841 aaatggtgcc tttccgttga taaccaagtc agaagaactt tcttctggtg gcaatttcaa
     9901 atcaacatcc actccagctt ctttgaaata acctttttcc ttggcaacat aaagccctgt
     9961 gtggttggta tttggtgtcc agtctaggat aaagtcaacc ttcttaagtt ctgcctcttt
    10021 gttgtcttta gaagcagttc cttgaccaca ggccacaagc acaacagcta caagagctgt
    10081 tacaagcgtt aaaaacactt tccatgtttt cttcattttg atttcctctt ttctttttca
    10141 gaaacattct aattctacga acgtttccat ttaatcacat atttttcact gatatcgacc
    10201 agcttcatac ccaaaagact gataatcgac accagaataa taatggcaaa catggtatca
    10261 tactgaaaca attttttaga ctgaatcata taaacaccaa gaccttcaaa acctcccaac
    10321 cactcagata ccacagttgt gataaaggcg taggagacac tgaccctcag acctgcataa
    10381 aagtaaggca ggctaactgg gattttaaaa tgccacagga tttgccaagg cttggcccgc
    10441 atcagactaa acaaggtcag catatccttg tcgcaatgcc taaaaccgtc caaaatacta
    10501 acgatgatgg gaaaggttgt cgttaagata atcaagacaa tcttgggcaa aatcccataa
    10561 cctagccaca agaccaggat aggagctatg gcaatggtcg gaatggtctg aatgaccacc
    10621 atcatagggt aaatcaggtc attgagccaa gtcaaactat ccatgagcac agccataaga
    10681 caggcaatca aaactcccaa aatcagcccc agtaaagcca ctctcaaggt cgcccagcta
    10741 tggtgccaga gaaattctct gtcacgaaca aagggctgga gaatttcaag aggtgtcggc
    10801 aggataaact tggggagaag tttaagaaaa cctgctaact gccagattaa caagactccg
    10861 agaaagccca atagactaat gtgtcgtctc agtatacttc tcaagtttct catcaatact
    10921 taaaatctct cctacattta ttttgacatt ggcaaagaca ttgtctgcct cctgccctgc
    10981 cacttccagc gcttctttta gaatgcgcat aagctcatca aactcccctt ccaagaccgt
    11041 ttcaaatggt gtcactacca tcgtcacttc ttgagtttgc agataagcaa tgacctgatc
    11101 aataacagct atccgatcaa tcccctgtgc taggggtaaa acttgcaagg caatgcttgc
    11161 tttcataaga acctcctctt ctcgttttcc tttttaaaaa aagaaaaacc tttaccatac
    11221 atggaaaagg tgcaaaatta gactaagtat cgttccctcc gctggcatta cccagatcag
    11281 gtgcggtcga agtttaacac ttcctctcag actgtacaca gactcccata tattatatgt
    11341 atatatgata gcgcaaaata aaaaaaatgt caaggaaact gcttacagaa aagagcagga
    11401 aatttctcct actccaattt tctatactcg ttctccatca ctgtttactc tgtagccatc
    11461 caccgtcgta ttaatagcta aggcgcctga agagtaagaa taataccact taccagagac
    11521 ctggtaccag cctgttttca ttgcccctga actacccaga taataccacg agccattctc
    11581 ctttaaccat cctgtctgca tttcaccaga taatttcaaa taataccagc tagaaccatc
    11641 tttcagccat cctgttgatt tagaaccatt tgatttgaaa tgataccaac taccatttat
    11701 tttcttccaa ccgacagttg aactattatt ggatccatag ctagagatat ttcctgattg
    11761 attctgataa ttttgtgaag aagtcactcc ctctagctgt atatagcgac gacttccatt
    11821 ataggcagta taactcaacc acttgtagcc gtctttttca agtatctgat cataatgaac
    11881 cttctcccca ggataatagt aatcaatcac agttccgcta actaggggtt cagttttgat
    11941 agcagacttg gtcttaaaat aatgagttcc acctgttgaa gaaagaacag aattacctag
    12001 aggattttta ttcacagcct ccaattgaac ataacgataa cttccattat aggcagtata
    12061 actcaaccac ttatagccgt ctttttcaag tatctgatca taatgaacct tctccccagg
    12121 ataatagtaa tcaatcacag ttgcactaac taggggttca gttttaatag cagacttggt
    12181 cttaaaataa tgagttccgc ctgttgaagc tgaggattga ctattcccaa cactgccacc
    12241 atccaaatct ttaaaatgaa taaatcctgt catcgtgttt gcttttataa ctcgtttatt
    12301 ataggattct gtataaccat agttatattc ctcaatctca atctgatctc ccattacatt
    12361 tgacacccag gcaacatgac cataagttcc tgcagtagac caagtaatgg aaccaatcgt
    12421 cggtgtatta tctacacgat aaccttcccg acgagcacga tgtccccatt cattcgcatt
    12481 tccataagct gccggaattt caaaaccatt gacattactc aaacgaaagg ctacaaaaga
    12541 agtacactga cgagaataca tgcgccactg atcaatctcc tggctcccat ttttataata
    12601 agcaggataa tcatccccac gcgcaatcga tccatttcct ctggaatagg catagacact
    12661 atcaccagct gctagcatca atcctactac taaaaaagga acaagctttt taactgacat
    12721 cttcaagtaa taacttgttc ctcttgctat aaacggtaaa attttcattc ttcctccttg
    12781 aaaaataata taaagcgatg attgccttca cctaaattat tcggagaaaa aagaaaaagt
    12841 gagaaaattt ctcactttag tcaagataat gaatcaaatt cttttctgta agaatatctg
    12901 agtaagtaaa ggattcaacg taaacattaa cttgtttatc tccttccaca tccccaaact
    12961 ccacaataaa tagagatgga taaacttcaa ttagcttacc caatctattt ttttggcgct
    13021 tacgaccatt ctccaaagtc atttctacga cttgtccctc atgtgcctta atttcttctt
    13081 tgattttttt catcttggct acatctgtaa atgcatctga catcttatgc ctccctcttt
    13141 gagatacttg aaaatttatt gtattctttt tggaaaatca attccactgt tccacgagct
    13201 ccactacggt ttttctcgat aataacttcc accttattat ttgggatacc ctcctcttct
    13261 tcaccaccac gttcatagta gtcatcgcga tagagaaaag ctacgatatc agcgtcctgc
    13321 tcaatagacc cagattcacg aatatcagac aagaccggtc tcttgtcctg acgttgttct
    13381 acaccacgag aaagctgact cagagcgatt actggaacct tcaattcctt ggctagtatt
    13441 ttcaactgac gagaaatttc agaaacttct tgttgacgat tttctcgacc agttcccgtg
    13501 ataagttgca aatagtctat caaaatcaaa ccaagatttc cagtttcttg agccaattta
    13561 cgagaacgag aacgaatctc tgtaatccga atacctggcg tatcatcgat atagatactg
    13621 gcgttagcta gattaccctg agcaatagta tatttttgcc actcctcatc tgtcaattgc
    13681 cctgtacgga tagaatgtga ctccaccaag ccttctgcag ctaacatacg gtctaccaag
    13741 ctttccgcac ccatttcgag tgaaaaaata gcaaccgttt tgtccaactt agtcccaata
    13801 ttctgagcga tattcaaggc aaatgctgtc ttaccaactg ctggacgagc tgctaagata
    13861 atcaactcct cctcatgaag tcctgttgtc atatgatcca aatcacgata acctgtcgca
    13921 atacctgtaa tatcggtcgt ttgttgcgag cgagcttcca gatttccaaa gttgagattc
    13981 aacacatctc gaatgttctt aaacccgctt cgatttgcat tttcactgac atcaatcagc
    14041 cctttttctg cctgagcaat aatttcatca gctggttgtg acgcttcgta agcttggttg
    14101 acagactctg tcaacttggc aattaaacga cgtagcattg ctttttctgc aacaatctta
    14161 gcataatact ccgcattagc agaagttggc acagaattaa caatctcaac caagtaagac
    14221 aagccaccaa tattctgtaa atcaccttga ttatcaagga tagtacgaac cgttgttgca
    14281 tctatggcat caccacgatc ggataaatcg accatggctt ggaaaatcaa acgatgggca
    14341 tacttaaaaa agtcccgaga ctcaatgtat tctcgcacaa aaacaagttt actctcatca
    14401 ataaagatag cccctaaaac ggattgctca gctaagatat cttgaggttg tactcgtaac
    14461 tcttctactt ctgccatcag acttcccttc cttttacaat cttgtcaaga aggtgtaaac
    14521 ttatccttct ttcacacgaa gattgattac acttgtgata tcttgataga ttttcactgg
    14581 cacatcaatc aaaccaaccg ctcgaatcgg agcttgtact tgaatatgac gtttatcaat
    14641 cttaattcca aattgctttt gtaattcttc tgcaatcttc ttattggtaa tagaaccaaa
    14701 ggtacgacca tctggaccaa ctttttcaac aaattctaca acagtttctt ctgcttcaag
    14761 ttgtgcttta attgctttcc cttctgcaat catctcagcg tgagcttttt cttccgattt
    14821 ttgtttacca cgaagttcac ctacagcttg agcagtcgct tctttggcta gattcttttt
    14881 gataagaaag ttttgcgcat accctgttgg tacttcctta atttcgcctt ttttaccttt
    14941 tcctttaaca tctgctaaaa agattacttt cattcttctt tctccttttc ctttatttca
    15001 tttaatacaa tttctgtcag tttttcacct gcttctgaca aggttacatc tttaatttga
    15061 gctgctgcca aattaaagtg gcctccaccg cctaactctt ccataatccg ttgtacattc
    15121 agtttactac gacttcgagc tgagatagag ataaatcctt gtgtattctt cgcaagaaca
    15181 aaactcgctt caatacctga catggctaac atggcatctg ctgccttact aataacaact
    15241 gtatcatagc atttcgtgtc cttagcctct gctattagta catctgaacc taatttacgc
    15301 ccctgtaaaa taagttcatt gacctcacga tattcttcaa aatctgtcgc agcgatttcc
    15361 tggatagcaa tactatcact tccgcgcgtt ctgagatagc tagcaacatc aaatgtccga
    15421 ctagttactc gcgaggtgaa atttttagta tccaacatca taccagccat caagacactt
    15481 gcttgcatac gactcaaacg atttttctta gaattctgga actgaatcaa ttccgttacc
    15541 aactcactgg cactacttgc accactttcg atataagtaa taaccgcatt atctggaaaa
    15601 tcctgatccc ttctatggtg gtcaataaca atggtttggg taaataaatc ataaaattct
    15661 tttgataatg ttaaggctgt ctttgaatgg tctacaagaa tcaacaaaga acgattggtc
    15721 accatcccca ttgcatcctt aacagacaac aacttcgtaa ctccttcttt ttctatgaat
    15781 gaaacagctc gttcaatatc tggagacatt tgttcttcat cataaagagc atagctattt
    15841 tcaatcacat tgctggcgaa caactgcata cctacagcag agcccaaagc atccatgtct
    15901 aaatttttgt gaccgactac aaaaacctga tctacactcc gaatcttatc tgaaatagct
    15961 gtcatcatag cgcgcgtacg agtccgtgta cgcttgattg aagcagcaga cccaccacca
    16021 aaataaactg gatttttcgt ttcgtcgttt tccttaacaa ccacctggtc gccaccacgt
    16081 acttcagcca agttcaaatt gagcaaagca actttcccta tctcatcatg atttccatcg
    16141 ccataagaaa atcccatact taaggtcaag ggcaactgtc tctgtttcga ctcttctctg
    16201 aaagcatcaa taacagaaaa tttatcattc atcaagccct caagcaccgt gtagtcagta
    16261 aatagataaa atcgatccat acttacccga cgagaaaaca tcatgtattt ttctgaaaac
    16321 tctgatataa aattagctac aaaactattg atttgactaa tatctgactc agaagttgca
    16381 tcctccaaat catcataatt atccacagag acaatcccaa tcactggtcg acttgttacc
    16441 aattcatctg ttatggcttg ttccctggat acatctacaa aatacaaaac accggaagaa
    16501 gcatccatat gaacagcata acgcttctca ccaagcttgg cataagtaga cggatttcct
    16561 actgaagcct tgataatcgt ttgaacagct tctaaatcaa aatcaccatc ttccttggtc
    16621 aaaatcaatt cagcataggg attaaaccac tcaacctctc cagaagataa attcaatttc
    16681 ataacaccta caggcatctg ttccaataga gctgtcaaac tttcttccgc ttggtggttt
    16741 acatactgta tctgttctac atcactcctt gtataatgca ctctcagttt cttaaataaa
    16801 aaaacatagc ctcctacaaa aagaaacaaa attaaaaccg tcaacagatt attattaaca
    16861 aaaataatga aagtggataa gactccaaac gcaatcaatc ctactagaat aggaaaaatt
    16921 ggacttacat aaaatttttt cattcaaaac ctcttggcac ccattatacc ataatacccc
    16981 tcaaaaagcg actttttaaa agtgtaatca gtaattctat caattataag aaaaaggtag
    17041 tttacaattc agtaaaccta cctttacaca tattgaaatt aagattcttt aacctctaac
    17101 aaaccaattt cgccatcctc acgacgataa atcacattgg ttgtctgatc ttcaacatcc
    17161 acatagataa agaaatcatg ccccaataaa tccatttgta gaattgcttc ttccaaatcc
    17221 attggtttta aatcaatttg ttttgaacga acaactttag actggacaac atttgaatct
    17281 tccaccaaag catctgtaaa taattgacca gttgctacct tatttttatt tttacgctcg
    17341 atttttgttt tatttttacg aatctgacgt tcaattttat cagttacaag gtcaattgaa
    17401 ccatacatat cttgagatac atcttctgcg cggagagtaa tagatccaag cggaatcgtt
    17461 acttccactt tagccgtttt ttcacgataa acttttaagt taattcgggc atccaactct
    17521 tgttctggtt ggaagtactt ttcgatcttt tcgagtttag aaactacata atcacgaatt
    17581 gcttctgtta cttctaggtt ttcaccacgg atactatatt taatcatatg agtaccttct
    17641 ttctaaacat ttttgttttt atgattttat tataacgctt tcattctatt tttgcaaatt
    17701 ttttcctcat cttacaaggg aaaatgtttt tacatcctta gcaccagctt cttccaacag
    17761 tttcttaaca cgatttatag ttgctcctgt agtatagata tcatctataa gtaggatttt
    17821 tttaggaata gtgactccac ttttaataaa gaaaggaagt tctgtcccca agcgctctga
    17881 acgattttta gaagaactgg ctctctcttc tcttttctct aataaatcca gatactcaaa
    17941 gcctgctgcc tctaccaagc cctcaacctg attaaatcct ctattagcat atctatcagg
    18001 acttagggga attacaacaa attgatactc tttgtacttt ttcaactcct cacttaaaaa
    18061 tgaagcgaaa acttttctta acaggaagtc tccatcaaac ttataccgac tgaaaaaatc
    18121 cttcatagct tgattgtaag taaaaatcgc tctatgactg acttcaactc cctctttaca
    18181 ccaaagttga caatcttgac actttgttga caactctgtt ttcatacaat ttggacagtt
    18241 ctcttcccca attctttcaa aagtagaatc acagtctgaa caaagacaag agtcatcatt
    18301 cctcagaagt aagagactac taaaagttaa aacagtcttc atagtctgcc cacataacaa
    18361 gcacttcata gaccagcctc cttattcatc atctgaattt ccttaatcgc cttcttgatt
    18421 gaagcattta acccatcatg gaagaaaagc aaatctcctg tcggtctatc catgcttcgt
    18481 ccaactcgtc caccaatctg aatcaaacta gacttggtaa acaaacgatg attggcctct
    18541 actacgaaaa catccacaca agggaaggta actccacgct ccaagattgt cgtactgata
    18601 agtattgtca gttctccatc tcgaaaagct tgtacttgct ctaatcgatc ctctgttaca
    18661 gaagatacaa agccaatttt ctcatttgga aattgctcct gtaagatttc tgctaactgc
    18721 tcccctttct taatttctga agcaaaaatg agtaacggat aagctgtctt tctctgcttc
    18781 tcaatatagg actttaactt tggtgacaaa cgattcttgt ctaagtagcg attaaaatcc
    18841 gataaccaaa ttggttttgg aataatcaac ggatttccat gaaaccgtct cggtaaattc
    18901 agtcttttta gttctcctaa acggaccttt ttatctaact cattggtcga agtcgctgtt
    18961 aaaaagattc tcaatccatt ctcctttaca ctattcttga cagcatggta aagcgtggga
    19021 ttatcaacat aaggaaaagc atctacttca tccactatca gcaaatcaaa agcttgataa
    19081 aacttcaata actgatgggt tgttgcaaca actagtggtg ttcgaaaata aggttccgat
    19141 tctccatgta gcaaagctat cccgcaagaa aaatcctgtt gcaggcgctt gtacagctcc
    19201 aaacaaacat ctatgcgagg actagccaaa cacactgcac cacccgcatt gatcacttta
    19261 gccactactt gataaatcat ttctgtcttt ccagctcctg ttaccgcatg aactaaggtt
    19321 ggcttttgct tgtctactgc ttgaagcagt ccctctgaca ccttctcttg aaaaggagtt
    19381 aattggccgc gccatttgag aacatcttgc ttcggaaaat cctcctgcgg aaaatagtat
    19441 aaagtttgat cacttctgac tcgcttcatc agcaagcact ctcgacaata gtaagcaccg
    19501 atgggcaaat accattcttc tagaatagtg ctattacaac gttgacagaa aagtttcccc
    19561 ttctcctttc tcattgctgg aagtttctcc gccaactgac gttcttcttc tgttaattca
    19621 ttctcagtaa ataaacgacc gagataatct aaatttactt tcatacttct ttattcgtaa
    19681 aaactagcac tttagatgat tttttagtac aattaaatca tggaatttag gacaattaaa
    19741 gaggacggcc aagtccaaga agaaatcaaa aaatctcgct ttatctgcca tgccaagcgt
    19801 gtttatagcg aagaagaggc tcgtgacttc attactgcca tcaaaaaaga acactacaaa
    19861 gcgacacata actgctctgc ctttattatt ggagaacgta gtgaaattaa acgtacaagt
    19921 gatgatggtg agcctagtgg tactgctggt gttcccatgc ttggagtact agaaaatcac
    19981 aatctcacca atgtctgtgt ggtcgtgaca cgctactttg gtggtattaa actaggcgct
    20041 ggaggactaa ttcgtgctta cgccggcagt gtcgccttag ctgtcaaaga aattggtatt
    20101 attgaaataa aagaacaggc tggcattgct attcaaatgt cttatgctca gtaccaagag
    20161 tacagtaact tccttaaaga acatgatctc atggagctgg atacaaactt tacagatcaa
    20221 gtcgatacga tgatttatgt tgataaagaa gaaaaagaaa ctattaaagc tgcacttgtg
    20281 gagtttttta atggaaaagt cactttaact gaccaaggtt tacgagaggt tgaagttcct
    20341 gtaaacttag tgtaaacaat gaataataca gcgtttcgtt gacattctca caactacttt
    20401 agcgagcaaa ataaaaagat gcgtaccaaa atatactaga aaatgaagca attcaaacga
    20461 aacctgatat cgttttcctt cacacctatt tactagaatt aactgaacgc aatcacttga
    20521 aaattaatga ctttgatcta tgatatatag aaatggtatg gatagcgtta tactaaagat
    20581 atcttataca aagaggtatt catatgtcta tttataacaa cattactgaa ttaatcggtc
    20641 aaacaccgat tgttaaactt aacaacatcg tgccagaagg tgctgcagac gtctatataa
    20701 agcttgaagc atttaatcct ggttcatctg taaaagaccg tattgccctt agcatgattg
    20761 aaaaagctga acaagatggt attctgaaac ttggttctac tattgttgaa gcaacaagtg
    20821 gaaacaccgg tattggactt tcatgggtag gtgctgctaa agggtataaa gtcgtcatcg
    20881 ttatgcctga aactatgagt gtagaacgac gtaaaattat ccaagcttat ggtgctgaac
    20941 tcgtcctaac tcctggtagc gagggaatga aaggtgctat tgctaaggct caagaaatcg
    21001 ctgctgaacg tgatggtttc cttcctcttc aatttgacaa tccagctaat ccagaagtac
    21061 acgaaagaac aacaggagct gagatactag ctgctttcgg taaagatgga ttagatgcct
    21121 ttgttgctgg agtaggtact ggtggaacga tttctggtgt ttctcatgca ctcaaatcag
    21181 aaaattctaa cattcaagtt tttgcagtag aagcagatga atctgctatt ctatctggtg
    21241 aaaaacctgg tcctcacaaa attcaaggta tctcagctgg atttattcct gatacacttg
    21301 atactaaagc ctatgatggt atcgttcgtg taacatcaga tgacgctctt gcactcggac
    21361 gtgaaattgg tggaaaagaa ggcttccttg tagggatttc ctcagctgca gctatctacg
    21421 gagccatcga ggttgccaaa aaattaggta caggtaaaaa agtccttgcc ctagcaccag
    21481 ataacggtga acgttatctc tctacagcac tttatgaatt gtaaccgtcc aataacgaag
    21541 tctattgaaa aatctccaga ctagagaact cacggatagt tcctaatctg gagatttctt
    21601 atttgcactt ttcttgtaca actttagtcc atggtaaata ggcctctaaa acctctttgt
    21661 ttacgagagt ttccacgttt agaagacatt ctagaagata ggatagatat ttctcactat
    21721 ttataatgga ttgaaataag atatgaacaa atcgattacg acatgatggt aaagcgtaat
    21781 cccttgtttc tcagctttcc cagacaaaaa agtccaatag taagtcagct gactatcact
    21841 ctctagcacc ctataagaag tttcatccgc atgaagtaag ggctgagtca atagtctctc
    21901 tcgcaagagg ttataaaggg gctccaaata gtattgactc gtcttgatat gccgattaga
    21961 gatttcctta cgtgtgattg gtaaacccat cctagcccaa tcttcttctt ggcgataatt
    22021 gggtaccttc agattaaact tctgatggat ggtgtgagcg ataatagaag ctgagccaaa
    22081 gttattcgct aaaggggctt taggaatagg agatttcaca agcttatcca gatgattatc
    22141 ttttactcgt tatggacaat gctatatggc ataaatcaag taccttaaag attccgacta
    22201 atattggctt tgcatttatt cctccataca caccagagat gaaccccatt gaacaagtgt
    22261 ggaaagagat tcgtaaacgt ggatttaaga ataaagcctt tcaaattttg gaagatgtca
    22321 tgaatcaact ccaagatgtt atacaaggac tggagaagga ggtgataaag tccatcgtta
    22381 atcggagatg gactagaatg ctttgtgaaa acagatgagt ataaaaagaa agtcctcatt
    22441 tcaatagaaa tcacgacttt ctgatgaatt tatagtaaaa tgaaataaga acaggacagt
    22501 caaatcgatt tctaacaatg ttttagaagc agaggtgtac tattctagtt tcaaaccact
    22561 atatttgggg agtgatagaa aagcccttca taagcca
//
LOCUS       DAVKXA010000035        21779 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKXA010000035 DAVKXA010000000
VERSION     DAVKXA010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.035"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..193
                     /locus_tag="VW883_001427"
     CDS             <1..193
                     /locus_tag="VW883_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0274554.1"
                     /translation="ENTTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLT
                     SSELVYLMAHIRRLTKNLD"
     gene            211..2049
                     /locus_tag="VW883_001428"
     CDS             211..2049
                     /locus_tag="VW883_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0274555.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            2062..3477
                     /locus_tag="VW883_001429"
     CDS             2062..3477
                     /locus_tag="VW883_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0274556.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            3959..5005
                     /gene="pheS"
                     /locus_tag="VW883_001430"
     CDS             3959..5005
                     /gene="pheS"
                     /locus_tag="VW883_001430"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0274557.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            5005..5514
                     /locus_tag="VW883_001431"
     CDS             5005..5514
                     /locus_tag="VW883_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274558.1"
                     /translation="MIRKVEVADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            5591..7996
                     /locus_tag="VW883_001432"
     CDS             5591..7996
                     /locus_tag="VW883_001432"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0274559.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVIIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKYDGTAGELTATQKLRRQVRTIAE
                     GVGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPREELPNEINSFAFALTGLVAEKDFQTVAVPVDFFYA
                     KGILEALFARLGLQVTYTATSEIASLHPGRTAAISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPAAPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(8064..9065)
                     /locus_tag="VW883_001433"
     CDS             complement(8064..9065)
                     /locus_tag="VW883_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0274560.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNNWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNTTIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            9221..9624
                     /locus_tag="VW883_001434"
                     /pseudo
     CDS             9221..9624
                     /locus_tag="VW883_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            9750..10016
                     /locus_tag="VW883_001435"
                     /pseudo
     CDS             9750..10016
                     /locus_tag="VW883_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            10277..12526
                     /gene="metE"
                     /locus_tag="VW883_001436"
     CDS             10277..12526
                     /gene="metE"
                     /locus_tag="VW883_001436"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0274561.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVSAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLTVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEVILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            12590..13456
                     /gene="metF"
                     /locus_tag="VW883_001437"
     CDS             12590..13456
                     /gene="metF"
                     /locus_tag="VW883_001437"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0274562.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            14143..16356
                     /gene="pnp"
                     /locus_tag="VW883_001438"
     CDS             14143..16356
                     /gene="pnp"
                     /locus_tag="VW883_001438"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0274563.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDAILTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            16372..16989
                     /gene="cysE"
                     /locus_tag="VW883_001439"
     CDS             16372..16989
                     /gene="cysE"
                     /locus_tag="VW883_001439"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0274564.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            17001..17885
                     /locus_tag="VW883_001440"
     CDS             17001..17885
                     /locus_tag="VW883_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274565.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            17967..19310
                     /locus_tag="VW883_001441"
     CDS             17967..19310
                     /locus_tag="VW883_001441"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0274566.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            19303..19689
                     /locus_tag="VW883_001442"
     CDS             19303..19689
                     /locus_tag="VW883_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0274567.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            19693..20577
                     /locus_tag="VW883_001443"
     CDS             19693..20577
                     /locus_tag="VW883_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0274568.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            20714..21169
                     /locus_tag="VW883_001444"
     CDS             20714..21169
                     /locus_tag="VW883_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274569.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            21166..21312
                     /locus_tag="VW883_001445"
     CDS             21166..21312
                     /locus_tag="VW883_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274570.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            21455..21625
                     /locus_tag="VW883_001446"
                     /pseudo
     CDS             21455..21625
                     /locus_tag="VW883_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         6667 a         3958 c         4834 g         6320 t
ORIGIN      
        1 tgaaaataca acttattgtg acgatgatga tgaagacttg ttagcattaa tgaaaaataa
       61 atatcctaga gaatatgaat gtggtgaaca ggtggcaatg tttatacaaa ctgagtacaa
      121 ttatttgctg acttctagtg aattagttta tttgatggct catattcgtc gcttaacaaa
      181 aaatttagat taatagaata ggagaatacc atgagttata aagataaggt acaaaaaatc
      241 ctcgatgtaa ttggaggtga aaaaaatgtc aatagagtta cccattgtgt aacacgttta
      301 agattagaat taaaagatga aaatttagtc aatgatgatg atgtgaagaa gataccaggt
      361 gtaataggta ttatgaaaaa gaatggacaa tatcaaatta tacttggtaa tgatgtagct
      421 aattattata aagaattcgt taaacttggc aattttgaat ccgattcagt tgttcaaggg
      481 cacaaaggga atattttaga aagaatcatt gagtatatcg ctggttccat gactccaatc
      541 attccagcaa tgttaggggg aggtatgctg aaagtcttgg taattatttt accaatgctt
      601 ggtatattgc aatcagattc tcagactatt gcttttttga cattttttgg ggatgctcca
      661 tattatttct taccgctgtt attagcttat tctgcatcac aaaaattaaa agtaacatct
      721 acattagcta tgtctgtagc aggtgtactt ctccatccaa attttgttca aatggtgcaa
      781 tcagggaatc ctcttagttt atttggtgta cctgtgatac cagctagtta tggttcgtca
      841 gtcgttccaa ttcttattat ggtttggttg atgaaatata ttgaaaaaat gattgctaaa
      901 ttaacaccag ctgttactaa gagttttttg caacctacgc tagtattatt agtatcaagc
      961 tgtattgcct tagttgtagt cgggcctatt ggagtaattg ttggtgaagg attatcaaat
     1021 ctagttgggc aaatgtatga tgtagctgga tggcttacat tagctattct tggtgctatt
     1081 atgccattta ttgttatgac tggaatgcat tgggcttttg cacctatttt tttggcggca
     1141 tctattgcta ctccagacgt attaattctt ccagcaatgt tagggtcaaa cttagctcaa
     1201 ggggctgctt cgatggctgt tgcattaaag agtaaaaata ataatacaaa acaaattgct
     1261 tttgcagcag gtttctcagc cttacttgca gggattaccg aacctgcatt atatggtgtg
     1321 actttaaaat ataaaaaacc gctttatgca gctatgattg gtggtggatt agcgggatta
     1381 tttgcaggtc ttactagtgt taaagcgtat ctatttgctg tcccatcttt gatagcgttg
     1441 cctcaattta tttattctga tgtaccatca aatattgtaa atgctttaat tgtggcggtt
     1501 atttcggttg ttattacctt tgtattagct tatatatttg gaatcgatga agaagagagt
     1561 tctagcaatt tagaagttaa agctggagtt tcaaataaaa aaatgatatt ttctcctata
     1621 tcaggagaaa tcattccgtt aagcgatgtc caggataaaa cattttcaga taaactaatt
     1681 ggagacggag tagcgattat tccaagtgaa ggtaaggttt atgcaccatt tgatgggaaa
     1741 attacaaata tttttccgac taagcacgca attggattga agagtgatga gggtgttgag
     1801 ttactaattc atattggatt agatactgtt gagctaaaag gtcaaggttt tattagtcat
     1861 gtagaagaag gagacagagt tttcaaaaat cagttgattt ttgaaatgga cttgaattta
     1921 atcaagacta aaggctacga aacagttaca ccagtaattg taacgaatac caatgatttt
     1981 ctagatgtat tagtattacc taataatcag acaatcgagc attctaagga attactggta
     2041 atattataat ggaggaaagt tatgaccatt tttccagatg attttctttg gggtggagct
     2101 gttgcagcta atcaagtaga gggagcatat aatgaagatg gtaagggctt atcagttcag
     2161 gatgtgttac ccaaaggtgg attaggagaa gcaacagaaa atcctacaga agataactta
     2221 aaattgatag gtattgattt ttatcataaa tataaggaag atatatcctt gttttctgaa
     2281 atgggcttta atgtttttcg tacttctatt gcatggagta gaatttttcc aaaaggagat
     2341 gaggaagaac ctaacgaagc tgggttgaaa tattatgatg aattgtttga tgaactacat
     2401 gctcacggga tagaaccact tgtaactctt tcacactatg agactccatt atatttagca
     2461 agaaaatatc atggatggat tgataggaga atgattcatt tttatgaaaa atttgctcga
     2521 acagttttag aaaggtataa agataaagtt aaatattggc ttacatttaa cgaagtaaac
     2581 tctgttttgg aattaccgtt tactagtgga ggaatagata tacctaagga gaatctttcg
     2641 aaacaagaat tatatcaagc tatacatcat gaattagtcg cctcgagttt ggttacaaaa
     2701 attgctcgtg agattaattc agagtttaag gtggggtgta tggtattagc tatgccagct
     2761 tatccaatga ctccaaatcc aaaagatgta tgggcgactc atgagtatga gaatctaaat
     2821 tatctatttt cagatgtgca tgttagaggt tattatccga attatgcaaa aagatatttt
     2881 aaggaaaatg acattaacat agagtttgca gctgaagatg cagagttatt aaaaaattat
     2941 actgtagatt ttttatcctt tagctattac atgagtgtga ctcaatctgc tcttccaaca
     3001 cagtataatt caggagaagg gaatattatt ggtggtttag taaatcctta tttagagtct
     3061 tctgagtggg gatggcaaat tgatccaatt ggactacgta taattttaaa tagatattat
     3121 gaccgttatc aaattccatt atttatagtg gaaaacggat taggtgctaa agatcaacta
     3181 ataaaagatg aatttaataa cttaacagtc caagatgatt atagaattca gtatatgaaa
     3241 gaacatttat tgcaagtagc tgaagctcta caagatggtg tggaaattat gggctatacg
     3301 tcttggggat gtattgactg cgtttctatg tccactgcac agctttctaa gaggtacggt
     3361 ctcatttatg ttgatcgaaa tgatgatgga aatggcacat tcaatcgata taagaaaatg
     3421 tcctttactt ggtataaagg agtgattgaa tcaaatggag aatccttatt caaatagttt
     3481 tttattgatg actagctatt atcacggtta aggtggcatt tcattaaata tggaataaag
     3541 aagtttggaa gacattaaat tctaaacttc tttattttat aggggagtgt caattaattt
     3601 aattttgtta caaaaattat aaatagttaa tttagataaa ttgtttatat aaatttagat
     3661 aagaataagc taacaagcag aagtaagata ggtcttgcaa gaatggtaaa aatctgataa
     3721 actaagtagt aattgaatag gaatctgaaa gactagtagc ccaagggaag tatatcaggg
     3781 aggagagccg tgactgcaag ctctctatat gaaagctggg tgaattcact tgcgcatgga
     3841 tttagaaatg aaggtctgac ttgtcagatg aaaacggatg gtaccgcgtg tcaacgctcc
     3901 gagtggagtt tttggcatgt ggttttcttt ttatctacga gagactgatg gaggaaatat
     3961 gtcaactatt gaagaacaat taaaagcgct tcgcgaagaa acgctgacta gcttgaagca
     4021 gattactgct ggaaatgaaa aagagatgca agatttgcgt gtctctgtcc ttggtaaaaa
     4081 gggttcgctc actgaaatcc tcaaagggat gaaagatgtt tctgctgaga tgcgtccaat
     4141 catcgggaaa cacgtcaatg aagctcgtga tgtcttgaca gctgcttttg aagaaacagc
     4201 taagctcttg gaagaaaaga aagtcgcggc tcaactggct agcgagagta tcgatgtgac
     4261 gcttccaggt cgtccagttg cgactggtca ccgtcacgtt ttgacacaaa ccagtgaaga
     4321 aatcgaagat atcttcatcg gtatgggtta tcaagtcgtg gatggttttg aagtggagca
     4381 agactactat aactttgaac gtatgaacct tccaaaagac cacccagctc gtgatatgca
     4441 ggatactttc tatatcactg aagaaatctt gctccgtacc cacacgtctc cagttcaggc
     4501 gcgtgctatg gatgcccatg atttttctaa aggtcctttg aagatgatct cgccagggcg
     4561 tgtcttccgt cgcgatacgg acgatgcgac ccacagtcac caattccacc aaatcgaagg
     4621 cttggtagtt gggaaaaata tctctatggc tgatcttcaa ggaacgcttc agttgattgt
     4681 ccaaaaaatg tttggtgaag agcgtcaaat tcgtttgcgt ccatcttact ttccattcac
     4741 agagccatct gttgaggtgg atgtttcttg cttcaaatgt ggtggagaag gctgtaacgt
     4801 atgtaagaaa acaggttgga tcgaaattat gggggccggt atggttcacc cacgtgtcct
     4861 tgaaatgagt ggtatcgatg cgactgtata ctctggcttt gcctttggtc ttggacaaga
     4921 gcgtgtagct atgctccgtt atggaatcaa cgatatccgt ggattctacc aaggagatgt
     4981 ccgcttctca gaacagttta aataatgatt agaaaagtag aagtggcaga tgttgaggtg
     5041 ttggctaaaa ttgccaaaca aacctttcgt gaaacctttg cgtatgataa tacggaagag
     5101 cagttacagg aatactttga agaggcttat agtctaaaaa ctttgtcaac tgagttggga
     5161 aatcctgact ctgaaaccta tttcattatg catgaggagg agatagctgg ttttctcaaa
     5221 gtcaactggg gaagtgctca aactgagaga gaattagagg acgcttttga aattcaacgc
     5281 ctctatgtgc tacaaaaatt ccaaggattt ggactaggta agcaactgtt tgaattcgca
     5341 cttgaacttg ctacaaaaaa tagtttttct tgggcttggt taggtgtttg ggagcataat
     5401 acaaaagctc aagcgtttta taatcgatat ggttttgaaa aatttagcca acatcatttt
     5461 atggttggtc aaaaagtaga tacggattgg ttactgagaa agaaattaag gtaagaagag
     5521 gattcttcta ttgaaatgat aggaaaggaa aagaactaga gtgacaactg tcattctgga
     5581 gaactaaatt atgcttgtat cttataaatg gttaaaagaa ttggtggaca ttgatgtgcc
     5641 atcacaagag ttggctgaaa aaatgtcaac tacaggaatc gaggtagagg gtgtcgaatc
     5701 accagctgct ggtctctcaa aaattgtcgt cggtgaggtc ttgtcttgcg aagatgtgcc
     5761 agagactcac ctccatgttt gtcaggttaa cgttggcgaa gaagaagagc gtcagatcgt
     5821 ttgtggtgcc ccaaatgtgc gtgctgggat caaggtcatg gtggctcttc caggagctcg
     5881 tatcgctgat aactacaaaa tcaaaaaagg aaaaatccgt ggtttggagt cacttggaat
     5941 gatctgttca cttggtgaat tggggatttc tgactcagtt gtgcctaagg aattcgcaga
     6001 tggcatccaa atcttgcctg aagatgccgt gccaggtgag gaagtctttt cttacctaga
     6061 cttggatgat gaaatcatcg aactttccat cacaccaaac cgtgcagatg ccctttctat
     6121 gtgtggagtg gctcacgaag tggcagccat ctatgacaag gcagtcaact ttaaagaatt
     6181 tactctaaca gaaactaatg aagctgcggc agatgccctt tctgtcatca ttgggacaga
     6241 caaggcgcct tactatgcag ctcgtatctt ggacaatgtg actatcgcac caagtccaca
     6301 atggttgcaa aaccttctca tgaacgaagg aatccgtccc atcaataacg tagtggacgt
     6361 gaccaactac atcctgctct attttggtca accaatgcat gcctttgact tggataactt
     6421 tgaagggact gacatccgtg tgcgtgaagc gcgtgctggt gaaaaattgg tgaccttgga
     6481 cggtgaagaa cgtgacttgg acgtgaatga cctagtcatc actgtcgcag acaagccagt
     6541 agcccttgca ggtgtcatgg gtggtcaagc aacagaaatc tctgaaaaat ctagtcgtgt
     6601 tgtccttgaa gctgctgttt tcaatggcaa atctatccgt aagacaagtg gtcgcctgaa
     6661 ccttcgttct gagtcatctt ctcgctttga aaaaggaatt aatgtggcaa cagttaatga
     6721 agcccttgat gcggcagcta gcctgattgc ggaacttgca ggtgcgacgg tgcgtaaggg
     6781 catcgtttca gcgggtgagc ttgatacttc agatgtagaa gtttcttcaa cccttgctga
     6841 tgttaaccgt gtcctcggaa ctgagctgtc ttatgctgat gtagaagacg tcttccgtcg
     6901 tcttggcttt ggtctttctg gaaatgcaga cagctttaca gtcagagtcc cacgtcgtcg
     6961 ttgggatatc acaatcgaag ctgacctctt tgaagaaatt gctcgtatct atggttatga
     7021 ccgcttgcca actagtctac caaaatacga tggtacagca ggtgaattga cagccacaca
     7081 aaaactccgc cgtcaagttc gtactattgc tgaaggagta ggtttgacag aaatcatcac
     7141 ctatactcta acaactcctg aaaaagcagt tgagtttacg gctcaaccaa gtaaccttac
     7201 tgaacttatg tggccaatga ctgtggatcg ttcagtcctc cgtcaaaata tgatttcagg
     7261 tatccttgat accgttgcct acaacgtggc tcgtaagaat aaaaacttgg ccctttacga
     7321 gattggaaaa gtctttgaac aaacaggtaa tccaagagaa gaacttccaa atgaaatcaa
     7381 cagttttgcc tttgccttga caggcttggt tgctgaaaaa gatttccaaa cagtagcagt
     7441 tccagttgat ttcttctatg ctaagggaat ccttgaagcg ctatttgctc gtttgggact
     7501 ccaagtaacc tatacagcaa catctgaaat cgctagcctt catccaggtc gtacagccgc
     7561 gatttcactc ggtgaccaag ttcttggttt ccttggccaa gtgcatccag tcactgctaa
     7621 ggcttatgat attccagaaa cgtatgtagc tgagcttaac ctttcagcta tcgaagctgc
     7681 gcttcagcca gcggctccat ttgtggaaat cacgaaattc ccagcagtca gccgtgacgt
     7741 tgcccttctc ctcaaggcag aagtgactca ccaagaagtt gtagatgcta tccaagctgc
     7801 cggcgtgaaa cgtttgacag atatcaaact ctttgacgtc ttctcaggtg aaaaactggg
     7861 acttggtatg aagtcaatgg cttatagctt gaccttccaa aatccagaag acagcttaac
     7921 ggacgaagaa gtcgcacgct acatggaaaa aatccaagcg tctctcgaag aaaaagtcaa
     7981 tgcagaagtg cgttaaacga tagtaggata caaattcccc ctctagttta tgaacactag
     8041 aggggtgatt ttatataaaa taattaaaat gtgatttctg taaaaataca tctatgatca
     8101 gagttttgaa aacttacaat gtctaaatct ttaacatagt agtggttttt aggcaataaa
     8161 atatgatcta ttgttgtatt aaaaagtttt ggactttggc tattccaagt tcctctttca
     8221 aaaggtggca gtacatttaa tgcgtcccta tgagagctta tttttgcaag tgctccatga
     8281 cgcatagttg cattaaaatc acctgcaata atagcctttg gatattttga agccaattga
     8341 ttatgaatga tgtttaagtc ttgcttccag atttccatta aacctggcag aggaggagca
     8401 gtatgcaagg caatgatatc tggtatattt tgttttctcg aatgtaatac aattgtcccg
     8461 aaccgtgttg tatgaaaagt tttagcttct gtatagaaac cataactttt cttgacaatc
     8521 acagtcacag gagctattcc actattggta ggtggagaag tgaaaatatc atagttggcc
     8581 atagaaagtc caacttgatg aaacaatagt ttgattctct ggttttcttg ctcacctctg
     8641 atattggtag ctagttcagg gaatatagcc atatcggcgt caaaatggct aaaaattcgc
     8701 tcaatatgtt gtgcttctat ttgattagcg acgttccaag ttactaattt taaggtttta
     8761 gtcttatttg atgcagaaga aagggtttta tctgttccga ataatagtaa tatgagcgat
     8821 agtaagagca aaatgccaga gtaaaaccgt atttgtttat ttttcttgta aaaagatagg
     8881 gaaaaaaata cgaaacttaa aatagaagcc atagttgcag tagctaaggg gaaggcataa
     8941 atctgtgcca agataggtct ggtagatagc caattattaa gattagaaga tggaaaaaaa
     9001 gaataagcta tgatagggat aacaaagaga atgaccgaaa gggcagagag aaatgtttta
     9061 atcattgtgt gagtacctca atttgcaatg gttgctcgga gctaatgtga ctttgtgact
     9121 ttacttgatt gatattcttt ttattgtctt ccttatagat taagtacaac ccaagtaaaa
     9181 aaagtccaat ttaagattga aatgattaaa aggcacagaa atgcaagaca attatactac
     9241 aaaaggcaaa catttgacaa tcgatagccg tcgcttaatc gaacgatgga aaaaagaagg
     9301 aaaatcaaat agagaaattg cctctctact tggaaaagct cctcaaacta tccacactga
     9361 aatcaagcgt gggacagtcc gacaatgtct tggaaaaggg cgcttcaaag aggtttattc
     9421 tgccgactac gctcaacagt cttaagaaac taaaggaaaa gattctccac tatacataac
     9481 caaaaatttt cgcctgaaat gatggttatg gttaaagggg ttaacgtggg aatttcaacc
     9541 atttactatt ggattcatcg tggaaaattg gggttaagca agcaggatct gctttatcct
     9601 agaaaaggaa aatcgcttaa gaaataggct agcaccaact ttaaacccac tggtcaatct
     9661 atcgaatcat aattcgctca tttttttaaa aatacataga cgtaaaaaaa agagggttaa
     9721 gtgatgaaga atagtgctat tgggagtaat tggaaggatg tccatctgag ctctttagca
     9781 aggaggaaat ccttgaaagt gatatgcgag tggctatcat gagcgagttg attgaggcta
     9841 ggtatgaaca aggaatcagt cagaaaaagc tggaagaagt cagtggaata agccagcctg
     9901 tcatagctag gatggagaca ggaaagacta gtccttagtt ggatacagtc ttaaaagtcc
     9961 tagccagttt aggaaagaca ctagcagtcg tcccacttga acagggaaaa agttgactag
    10021 aatcagttat agtcttttct aataacaggt catagtcact tataagaatt actaataaca
    10081 tgttttagta ttctaattgg aatatagctg taaagtaaga attacaaagg atttgagacg
    10141 tttgcttcaa gtctttttct tttgtccgaa acagatatat agtttcaaac tatatcaaac
    10201 cctaattttt tacaattata cagacgcttt cttttctgtt aagatagttt caacaacaaa
    10261 ttttggagga cacatcatgt caactacaat catcggtttc cctcgtttgg gcgaattccg
    10321 tgaattaaaa tttacaactg aaaaatactt tagaaaagaa atctcagaag aagaactttt
    10381 agcagcagca aaagacttgc gtgctaaaca ctggaacatt gtcaaagaaa aaggcatcac
    10441 tgaaattcca tcaaatgact tttctcacta tgataacttc ctagatgcgg ctttcctttt
    10501 caacgtggtg cctgcatccg ttcaaaactt ggacttgtct gaccttgagc gctacttcgc
    10561 tttgggacgt ggttaccagg gagaaaaagg ggacgttcgc gcccttccaa tgaagaaatg
    10621 gttcaacact aactaccact acatcgttcc taaatttgaa aaagacactc aagtaaaatt
    10681 ggctggtcac aagattttcg atgagttcca agaagccaaa gaacttggat tgaacactcg
    10741 tcctgttctt gtaggtccct tcactttcct tcaattgtca gactttgaag aaggcgtgaa
    10801 agcagacgac ttcgtagata gcttagtgtc tgcttaccaa gaagtttttg ctaaattggc
    10861 tgaacttggt gcgactcgca tccaattgga tgaagcggct cttgtaaaag acttgacagc
    10921 tgaagaaaaa gctcttttct tgaaccttta caacaaactc ttggctgaca aaaaaggtct
    10981 tgaagtcttg cttcaaactt atttcggtga tgttcgtgac gtatacgctg accttgtaaa
    11041 cttaccagta gatgctatcg gtcttgactt tgttgaaggt aagaaaactc ttgaactcgt
    11101 taaaggtggc ttcccagctg acaagactct ctatgtaggt attgtcaatg gtaaaaacat
    11161 ctggcgcaac aactacgaaa agagcttgac tgttcttgag caaatcccag ctgaaaacat
    11221 cgttttgaca agctcttgct cacttcttca tgtgccattt acaactgcta atgaagaatt
    11281 tgaaccagca ctcttgaacc actttgcctt tgcagttgaa aaattggatg aaatccgtga
    11341 cttggatgct atccgaaatg gtcaaggttc agaagctctt gcagccaaca aagaactctt
    11401 tgcgactgag cgtgttggtg aaaatgctga acttcgtgcg cgtatcgctg gcttgacaga
    11461 cgcagactac actcgtttgc cagcctttgc agaacgtgaa gctatccaag aagaagcttt
    11521 caaacttcca gctcttccaa caacaacgat tggttcattc cctcaaacaa aagaagttcg
    11581 tgccaaacgt ttggcttacc gtaaaggtga attgtctcaa aaagagtacg acgctttcct
    11641 tgctgaaacg attgacgaat ggatcaagtg gcaagaagat attgactttg atgtccttgt
    11701 tcacggtgaa tttgagcgta atgacatggt tgagtacttc ggtcaaaact tgtcaggata
    11761 cctcttctct aaaaatggat gggtacaatc atacggtatg cgtggggtaa aaccaccaat
    11821 catctggggt gatgtcactc gtcttaaccc tatcactgtt aaatggtcta gctatgcaca
    11881 aagtcgtaca aacaaacctg ttaaaggtat gttgactgga cctgttacca tccttaactg
    11941 gtcattccca cgtgaagaca tctctatcaa ggattcaact ctccaaatcg cccttgctat
    12001 caaggatgaa gtacttgacc ttgaagctgc tggtgtgaaa atcatccaaa tcgacgaggc
    12061 tgctcttcgt gaaaaattgc cactccgccg tagcgactgg tacgaagact accttgactg
    12121 ggctattcct gccttccgct tggtacactc aacagtagcg ccagacacac aaatccacac
    12181 tcacatgtgt tactcagaat ttacagatat catcccagct atcgataaca tggatgcaga
    12241 cgttatttcc tttgaagcta gccgttcaaa ccttgaaatc ttggacgaac tcaaagcgaa
    12301 aaacttccaa acagaagtgg gacctggggt ttacgatatc cactcacctc gtgtaccaaa
    12361 tgaaggcgaa atcgacaaca caatcgaagt catccttgct aaagtgccaa gcaagaaagt
    12421 ttggatcaac cctgactgtg gtttgaaaac acgtggtatc ccagaaacaa aagaaagctt
    12481 gatccgcctt gttgaagcag ctaaagctgc gcgtgagaaa ttgtaagatt ggatttctct
    12541 ccatacagtg gttgttcaaa aagaaatcaa ctagaaaagg ttattacata tgtcacgcca
    12601 aacaccgtca ctctcatttg aagtgttccc tccaaaccca gccgtgggta atgataacat
    12661 tatttcagcc ttgcaggata tgcaggagtt ggctccccat tttatcagtg taactgccag
    12721 caataataaa tttaatatca aggaaacgac ggttcgtttg gctgacttta tccaaaatga
    12781 tttggcgatt ccgaccattg cccacttgcc agctatttat ctaactaagg acaaggttgc
    12841 tgaaactatt gctgacttgg acaaagttgg ggtgcagaaa atcttggctc ttcgtgggga
    12901 tattattcca gacgtggaac cacaaaagga tttccgctat gcaacagact tgattgagtt
    12961 tatcaaggaa caaacccctc actttgatat tattggagct tgctatccag aagggcatcc
    13021 agattcgcca aatcagattt cagatattca aaatcttaag aagaaagtgg atgcaggctg
    13081 ttcgagcctc gtaactcagc tcttctttga caatgagcgc ttctatgact ttcaggacaa
    13141 gtgcatcttg gctgggattg atgttcccat tcatgcagga attatgccaa ttctgaatcg
    13201 aaatcaggct ctccgactct tgaagacttg tgagaatatc catcttccac gcaaatttaa
    13261 agccatctta gacaagtatg agcatgaccc tgagtcgctc agagcagcag gacttgccta
    13321 tgcagtggac caaatcgtgg acttggtaac tcaggatgtt gccggtgtgc atctctatac
    13381 gatgaataat gctgatacag caaaatacat ccatcaagca acccatgcct tgtttaatca
    13441 ccagtctcta ggataataaa agcaaaccat tcttctcagg tgaggggaat ggttcctttt
    13501 taatggtaaa gacctcactt tttaagaaaa atatgataaa ataaattctg tacgtacttg
    13561 atacaaagat gaaggtatta aataatacaa tgcatttaaa ctgtaagatt taacgacacg
    13621 agtgagtcaa atcgatgtta tttgacgaga gagttagtaa agcatttaac taatcgcccg
    13681 atagcgatta gcgtgaaagc tttagatact ttagtattaa acctttctaa tgatttatat
    13741 cttgaaaact gaactcgcct acaactctgt ggaaaaagat aaatctccct aggagcagtc
    13801 gctccgtcgt tcgatttcct attttccttt gagttgcttg acggcttagt atcttgatga
    13861 cttgaatttt ggtctcattt cttaggaaaa aagataagct tcctagcact cgtcgagtgc
    13921 gacgtcacct tcctattttt ctacagaaat gttcggcaag ccgaaccgtc caaaatatct
    13981 tgtgtaattg aacacggccg aaaagctgtg taaaaaagat aaactgtctt gtcttcatcg
    14041 aagacttcgt cagtttccta tttttacttt gcttttgacg tccttggtat cttgatcttt
    14101 gtaggcaagg cgtataattt catcaatcca aaggggatta aaatggcaaa acaagtgttt
    14161 caaacgactt ttgcgggtcg tgagttaatt gtagaaactg gtcaggttgc taagcaagca
    14221 aatggctctg ttgtcgtacg ttacggtgag tcaactgtct tgactgctgc cgttatgtct
    14281 aagaaaatgg caactgggga tttcttccca ctccaagtca actacgaaga aaaaatgtat
    14341 gcggctggga agtttcctgg tggctttatg aaacgtgaag gacgtccttc aacagatgcg
    14401 atcttgacag cgcgtttgat tgaccgtccg attcgtccta tgtttgcgga aggtttccgt
    14461 aatgaagtcc aagtcatcaa tacagtgctt tcttatgatg aaaatgcatc tgcaccaatg
    14521 gctgctatgt ttggttcatc tttggcactg tctatttcag atattccatt tgacggacca
    14581 attgctgggg tacaagtggg atatgtagat ggccaaatca tcatcaaccc aagtcaagaa
    14641 caagcagagc aatctcttct tgaattgaca gtagctggaa ccaagcacgc tatcaacatg
    14701 gtagagtctg gtgccaaaga attgtcagaa gaaatcatgt tggaagcgct tcttaaaggg
    14761 cacgaagctg tcaaagaatt gattgccttc caagaagaaa tcgttgctgc tgtcggtaaa
    14821 gaaaaagcag aagtggaatt gcttcacgtg gatgctgaat tgcaagctga aatcattgca
    14881 gcctacaaca gtgacctcca aaaggcagtt caagtagaag agaaattggc ccgtgaagct
    14941 gcaactcaag cagtgaaaga ccaagtgact gccgtttacg aagaaaaata tgcgaaccac
    15001 gaagaatttg accgtattat gcgtgatgtg gctgaaatct tggaacaaat ggaacacgca
    15061 gaagtgcgac gtttaattac agaagacaag gtgcgtcctg atggtcgtaa ggtcgatgaa
    15121 atccgtcctt tggatgcggt tgttgacttc cttcctcgtg tacatggttc aggtctcttt
    15181 actcgtgggc aaactcaagc tctttcagtc ttgaccttgg ctccgatggg agaaactcaa
    15241 atcattgatg gtttggatcc agagtacaag aaacgcttta tgcaccacta taacttccct
    15301 caatattctg taggggaaac aggtcgttac ggtgcgccag gtcgtcgtga aatcggtcac
    15361 ggtgcccttg gtgagcgtgc tcttgctcaa gtcttgccaa gcttggaaga attcccatac
    15421 gctatccgtc tagtagcaga agttttggaa tcaaacggtt cttcatctca agcttctatc
    15481 tgtgcgggaa ctcttgccct tatggctggt ggtgtgccaa tcaaggcgcc agtagctggt
    15541 attgctatgg gacttatctc agatggaaat aactacacag tattgacaga tatccaaggt
    15601 ttggaagatc actttggaga tatggacttc aaggttgcag gtactcgtga tgggattaca
    15661 gcccttcaaa tggatatcaa gattcaaggg attactgcag aaatcttgac ggaggctctt
    15721 gctcaagcca agaaagcgcg ttttgaaatc cttgatgtca ttgaagcaac cattccagaa
    15781 gttcgtccag aattggctcc aactgctccg aaaattgata cgatcaagat tgatgtggac
    15841 aagattaaga ttgtcatcgg taagggtgga gaaaccatcg acaagattat cgctgaaaca
    15901 ggtgttaaga ttgatataga cgaagaagga aatgtgtcta tctactctag tgaccaagat
    15961 gctattaacc gtgccaaaga aattattgct ggtttggttc gtgaagccaa agtggatgaa
    16021 gtttaccgtg ctaaagtcgt tcgtatcgag aaatttggtg cctttgttaa cctctttgat
    16081 aagacagatg cccttgttca tatctctgag atggcttgga ctcgtaccaa tcgtgtagag
    16141 gatttggtag aaatcgggga tgaagttgat gttaaggtta tcaaaattga tgaaaaaggc
    16201 cgtatcgatg cctctatgaa ggctcttcta cctcgtccgc caaaacctga gcatgatgaa
    16261 aaaggtgaaa agtctgagcg ccctcaccgc ccacgtcatc aaaaggatta caaacctaag
    16321 aaagaattta cagaaacatc aaaagattca gaataagaaa aggagaaatg tatggggtgg
    16381 tggcgcgaaa ccattgatat tgtaaaagaa aatgatccag cggcccgcac cactttggag
    16441 gttttgctga cttatccagg tgtcaaggcc ttggcggccc accgtctctc gcattttctc
    16501 tggaagcacg gcttcaaact attagctcgt atgtacagtc agttttggcg cttttggact
    16561 cagattgaga ttcatccagg agcccagatt gattcaggtg tttttattga ccatggttct
    16621 ggtctggtga ttggagagac agcgattgtt gaaaaaggcg ttcttctcta tcacggagtg
    16681 actctcgggg gaacagggaa agactgtggc aaacgccatc cgactgtacg aaagggagcc
    16741 ctcatatcag cccatgccca agttatcggg cctgtggaaa ttggtgaaaa tgccaaggtc
    16801 ggtgctgcag cagttgtcgt agcagatgta cctagtgacg tgacggttgt cggtattccg
    16861 gccaagattg tccgtcttca tggtaagaaa gatgagcctg tcattcacga agtcgaagaa
    16921 aaacgagagt attatgtcaa taaactcgag caggctaaag atgccagtca cagatcgtct
    16981 ggtttgtaga ggatacctat atgattcaag caagaaacaa gttaagccaa gaggagctat
    17041 ctgaggcgaa aaaagtaatt aactgttgcc aaaactatga cggtacctat cgcgatccct
    17101 atctctctaa catgcttaat tttgacccaa acatgcccgc ctttttcctt tattatgaaa
    17161 aaggcgaact tgttggttta ttaactgtct atgcagatga ccaagatgta gaagtgacga
    17221 tactggttca tccaggtcat cgccgtcagg ggattgcgcg tgcattgttt actagttttg
    17281 agagagaaac agcttctttc cccattcggt cagtcacttt tcagacagaa cgtatttttt
    17341 tagagaatca tcctgacttt gccagtaact ggggactaat cgaggatgaa gagacagaaa
    17401 cttggttagg taaggataga agaccttatc cgttagcaaa tgtttcccat cttgaagttt
    17461 tgttagcaga tagttcgtat caggatcaaa ttagtcaatt aaaatttcag gcattttcag
    17521 aggaacatga atcgagagaa gttgtggata gatatgtcgc tgaagctctg aaagatccag
    17581 aaagccgact atatatttta ttaaaagctg gtcaggttat tggaacttgt acggttgatt
    17641 tatcgactaa tacgaattac ctctacggtt tagcaatatt ggaacctgaa cgtggaaaag
    17701 gctatggaag ctacttagca aaatccctcg tcaaccaact aattgagcaa aatgacaagg
    17761 aatttcagat tgcagtggaa gatagcaatg taggtgccaa acgtttgtat gaaaaaattg
    17821 gctttgtcaa acagactcag gtggtttatc tgaatgagaa aggagcaagg gattccgaag
    17881 tgtagagata ttcggactga aatttacttg aacttttagt gatgaaacta attgttcttg
    17941 gatttcagct ttcctgatta tgatttatga ttaaaatcta tgacaccatg tctcgtgatt
    18001 tgcgagaatt tgtcccgatt gaggacggca agatcaagat gtatgtttgt gggccaacgg
    18061 tgtacaacta tatccacgta ggaaacgccc gttcgacggt agcttttgat acgattcgtc
    18121 gctattttga gtaccgtggg tataaggttg cctatatttc caattttaca gatgtggatg
    18181 ataagattat caaccgtgcc agggaagaag gtatcacgcc tcaggaggtt gcggataagt
    18241 acatcgctgc ctttcgtgag gatgtgacgg cattgggcgt gaaacctgcg actcgccatc
    18301 cgcgtgtagt ggagtttatg gcagacatca tccgttttgt ggaagacttg atcgagaaag
    18361 gctttgccta tgagagtcaa ggggatgtct atttccgtgt agaaaaatcc cacaactatg
    18421 ctaaattggc taataaaacc ttggaagatt tggagctagg tgcttcaggt cgtaccgatg
    18481 aagaaacggc tcgtaaggaa aatcctgtag actttgctct atggaaatct tccaaaccag
    18541 gtgagatttc ttgggatagt ccttggggac ctggacgtcc gggttggcat attgagtgtt
    18601 cagtcatgtc gacagagatt ttaggtgata ccattgatat ccacggtggt ggagctgacc
    18661 tagagtttcc acaccacacc aatgaaattg cccagtctga agctaaaaca ggcaaggctt
    18721 ttgctaacta ctggatgcac aatggctttg tcaatatcga caatgtcaaa atgtctaagt
    18781 ccttgggtaa cttcattacg gtacacgatg cccttaaaac tcttgatggg caagtacttc
    18841 gtttcttctt tgcgacccag cactaccgta agcctatcaa cttcacggaa aaggcagttc
    18901 gcgatgccga gaccaatctc aagtatctca agaatactta cgaacaacca tttacaggaa
    18961 atgtggatgc ccaagagtta caaaacttta aagataagtt tgtagcagct atggatgaag
    19021 attttaatgc tgccaacggt atcacagttg tctttgaaat ggccaaatgg atcaactcag
    19081 ggaactatga tgcaagtgtc aagcaagctc ttgcagatat gttagaaatt tttggaattg
    19141 tctttgttga ggaagttttg gatgcagaga ttgaagactt gattcaaaaa cgccaagagg
    19201 cgcgtgccaa tcgtgacttt gcgacagcag accaaatccg tgaccaattg gttactcaag
    19261 gaattaagct ccttgatacc aaggatggag tgaggtggac acgtgattga tgtcaatctc
    19321 attaacggga ttgcgctagc ctttgagggg gatgcggtgt attctatgta tattcgccgt
    19381 cacctcatcc tcaaaggtat gaccaaaccc aataaactcc atcaagaagc aactaagtac
    19441 gtgtcagcca aggctcaggc tcgcctgatt gctctcatgt tggaggagca ggtcctaacg
    19501 gaaaaagaag aagaaatcta caaacgtggc cgcaatacca atagccacac aaaggctaaa
    19561 aatgcagatg tcgtgactta tcgtatgtcc acgggatttg aagcggttat gggctatctc
    19621 catatgactg agaatctgga acgtcttgag agtttggttt catggtgcat ccaaaaagtg
    19681 gagggctaga acatgagggc aaaagaacta caagactggt ttcctgaggc tcggatttca
    19741 gaccaaccag tagagaaaga gggctatctc acgctccctt tagcttctca gcagtggatt
    19801 ttgctggagg aagctgggct cagcgagcgt gaaaagcagt tggttgccct tttgacccag
    19861 caggagcagg ctcgttcgct aaacccttgg tattcctatc tggttgaggg caagggacag
    19921 gcaccgcaag tttttaaaaa gattcagttg gtttattgcc atctttctta ttttcagcag
    19981 gaaaatctgg cttcttggct agatatgatg cggactcttt ttccgaattg tcagacagtg
    20041 ctacaggtcg gagctcagga ttatgttttc gtgcttcaac aagacaaata cacttctgta
    20101 agagatattt taagtgatac gattgaagcg gttgagtatg actttggact tcgtctttct
    20161 atcatgttgg gtcaggtttg gtctcagacg ggacatcaag ccctatcaga cttaatcaaa
    20221 gctgagcggg atttgttcaa gacatggtgg cgtcagggtc accaaggtgt tcatactttt
    20281 tctcagctct atctttggag tatgggagaa agactcgtgg acttgaagcc aatcaaggaa
    20341 tgtctacacc agatgatttt ggatcaagat cagattcagg aaatcattct ctctctttgg
    20401 gaaaatagtg ctgttctcac taaaacagcc cagcaactct atctgcaccg caattctctc
    20461 caatacaaga ttgataaatg ggaagagttg acagggcttc agttgaaaga gttgaccgac
    20521 ctgaccttgt gttatcaatt gattttaggt tctttgtcaa ctatagttgg tttgtaaaga
    20581 agttaatatt tggagaagag gattgccatc ttctccattt ttatgtgcag agttatagtg
    20641 gcttgatgct gggaaagtac actgtgactg ctaaaacatt cctagaagct gctttgattt
    20701 ccctaatcta tttatgcaaa ttttatgtta ttttactata acagttgttg ctaagccaaa
    20761 taatagtggg gaagttcatt tagacgtaag cattgaagat aatcagggag gtagtgggta
    20821 taatttcagt tctgtttcaa gtagctcaca aacagctaaa tatgaaggaa ctgtttataa
    20881 taacaattca tcattatata taacgattga taaaacgtct gatgcaacag ctcttttgaa
    20941 attaaagttg aataatgttg ataatcaacc tgctactgaa gttcctagtt caggaattac
    21001 tgtaaaatta aatgctaaag ataatgctgg aaactggaca agtgcttcga ataaaaaaga
    21061 agtaacagta aaaattgttt ctgctaaacc gacatatcca gacaaaatct tagtgaaaaa
    21121 tcctgataat ataaaagata cagaaaaaat gccattattg aaaaattgaa agaggcaaat
    21181 aaaaatcatc cagcaggagc tccaaccttt gctaaaggtg aaggagagca tgcaaatgat
    21241 attgtagcaa cttattcaga tggtacaact tattatgtac cgttaaatga tgtgacaaaa
    21301 tatgcgaggt agtggctgta ccactcactt attcacctcc ccgtgatttg tagtagtgat
    21361 aggctttctc actattatta taaaacaaaa taaagatcac aacacttttt cattctgtgt
    21421 tgtgccttga gtgaaacgaa aggaatgaat tataaatatg aaaagtatag tcactagcat
    21481 agatgagcgc ttgcgtactc gcctacgagt gattatctgg aagcaatgga agaagaaatc
    21541 gagatgatta tggggattgc ttaagttagg ggttcctaaa tggatagcag ataaggtatc
    21601 tggctggggc gaccactatc aattatatta aaatgaaata agaataggac gaatcgatca
    21661 gggaagtcaa atcgatttct aacaatattt tagaagtaga ggtatattat tctagtttca
    21721 atctactata gtatctcaga agtcggtact taaacgtgct atatcaaaac cagtccttg
//
LOCUS       DAVKXA010000036        21644 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKXA010000036 DAVKXA010000000
VERSION     DAVKXA010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.036"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(288..506)
                     /locus_tag="VW883_001447"
     CDS             complement(288..506)
                     /locus_tag="VW883_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0274571.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(752..1030)
                     /locus_tag="VW883_001448"
     CDS             complement(752..1030)
                     /locus_tag="VW883_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274572.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1244..2875)
                     /gene="rlmD"
                     /locus_tag="VW883_001449"
     CDS             complement(1244..2875)
                     /gene="rlmD"
                     /locus_tag="VW883_001449"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0274573.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGLAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2949..3923)
                     /locus_tag="VW883_001450"
     CDS             complement(2949..3923)
                     /locus_tag="VW883_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0274574.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDSDKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3997..4611)
                     /gene="pmp23"
                     /locus_tag="VW883_001451"
     CDS             complement(3997..4611)
                     /gene="pmp23"
                     /locus_tag="VW883_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0274575.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4611..5585)
                     /locus_tag="VW883_001452"
     CDS             complement(4611..5585)
                     /locus_tag="VW883_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0274576.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5593..6849)
                     /locus_tag="VW883_001453"
     CDS             complement(5593..6849)
                     /locus_tag="VW883_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0274577.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6910..7341)
                     /locus_tag="VW883_001454"
     CDS             complement(6910..7341)
                     /locus_tag="VW883_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274578.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            complement(7343..7945)
                     /locus_tag="VW883_001455"
     CDS             complement(7343..7945)
                     /locus_tag="VW883_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0274579.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7929..8768)
                     /gene="prmC"
                     /locus_tag="VW883_001456"
     CDS             complement(7929..8768)
                     /gene="prmC"
                     /locus_tag="VW883_001456"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0274580.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8768..9847)
                     /gene="prfA"
                     /locus_tag="VW883_001457"
     CDS             complement(8768..9847)
                     /gene="prfA"
                     /locus_tag="VW883_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0274581.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9857..10336)
                     /locus_tag="VW883_001458"
     CDS             complement(9857..10336)
                     /locus_tag="VW883_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274582.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10326..10925)
                     /locus_tag="VW883_001459"
     CDS             complement(10326..10925)
                     /locus_tag="VW883_001459"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0274583.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            11048..11230
                     /locus_tag="VW883_001460"
     CDS             11048..11230
                     /locus_tag="VW883_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0274584.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11367..12740
                     /gene="mnmE"
                     /locus_tag="VW883_001461"
     CDS             11367..12740
                     /gene="mnmE"
                     /locus_tag="VW883_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0274585.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12787..13722)
                     /gene="dapA"
                     /locus_tag="VW883_001462"
     CDS             complement(12787..13722)
                     /gene="dapA"
                     /locus_tag="VW883_001462"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0274586.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13778..14854)
                     /locus_tag="VW883_001463"
     CDS             complement(13778..14854)
                     /locus_tag="VW883_001463"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0274587.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15196..15268)
                     /locus_tag="VW883_001464"
     tRNA            complement(15196..15268)
                     /locus_tag="VW883_001464"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15233..15235),aa:Thr,seq:ggt)
     gene            complement(15368..15877)
                     /locus_tag="VW883_001465"
     CDS             complement(15368..15877)
                     /locus_tag="VW883_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0274588.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15875..15971)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            16000..16431
                     /locus_tag="VW883_001466"
     CDS             16000..16431
                     /locus_tag="VW883_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0274589.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            16513..16890
                     /gene="mscL"
                     /locus_tag="VW883_001467"
     CDS             16513..16890
                     /gene="mscL"
                     /locus_tag="VW883_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0274590.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16932..18026)
                     /gene="hemH"
                     /locus_tag="VW883_001468"
     CDS             complement(16932..18026)
                     /gene="hemH"
                     /locus_tag="VW883_001468"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0274591.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            18180..19400
                     /gene="pepT"
                     /locus_tag="VW883_001469"
     CDS             18180..19400
                     /gene="pepT"
                     /locus_tag="VW883_001469"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0274592.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(19443..20072)
                     /locus_tag="VW883_001470"
     CDS             complement(19443..20072)
                     /locus_tag="VW883_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274593.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTTGNQEKPVE"
     gene            20037..20258
                     /locus_tag="VW883_001471"
     CDS             20037..20258
                     /locus_tag="VW883_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274594.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(20529..20962)
                     /locus_tag="VW883_001472"
                     /pseudo
     CDS             complement(20529..20962)
                     /locus_tag="VW883_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149760.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(21066..21626)
                     /locus_tag="VW883_001473"
                     /pseudo
     CDS             complement(21066..21626)
                     /locus_tag="VW883_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6271 a         4488 c         3981 g         6904 t
ORIGIN      
        1 agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa taaaaatttg
       61 tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat cattcatatt
      121 tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta attgattaaa
      181 agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa agcctatact
      241 tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta ttcctcgtca
      301 ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc cttacatatt
      361 ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat aacatttgtt
      421 gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc taactgtatc
      481 cataatggtt tatagttaag tgccataata tccctctttt tttcttcatt aaatttattt
      541 aattatagca taaatattga tttcattcaa tcttacattg atttagtgat ttgttttaga
      601 gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg ggacctctta
      661 tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt ttttaatttc
      721 tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt aaagaatctt
      781 taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatattg taagcagcac
      841 accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc cttatattta
      901 cataactatt tgcctctata actgttatga cacgaaacca acaagcaagt tcaagcacct
      961 ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa acctctttat
     1021 cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt ttgttgcctt
     1081 tatcaatcat ttcaacgctc ctttaaatat aaaaatgatc ctatcaatct ttatattgag
     1141 cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat accaagtagg
     1201 aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc attttgaagt
     1261 gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga ataatttgtt
     1321 tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc ttttttatct
     1381 gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat tctttgattt
     1441 gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc tcaatttcaa
     1501 cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg acgtgatgcg
     1561 tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaac tcttggtata
     1621 gtttaatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg cgatcggctc
     1681 ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga ggatcaacca
     1741 agataacggt tggttgaatc ccatctttaa gccaattctt catagcattt tcagctgtgt
     1801 cacagacata gtgggcgttt gaaatattgt tcagctgagc atttttttta ctattctcaa
     1861 ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg actgataaac
     1921 caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt aactctgcaa
     1981 agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg taaaaggcta
     2041 ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct tgaccataaa
     2101 gagtgcgcca ctccttacca aaaatcgcat tggtattctg gtcgttgata ttttgcatga
     2161 cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca acacgaaaaa
     2221 cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga ccacgacgca
     2281 ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt aaatcaaaac
     2341 gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc tggataaaga
     2401 aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt tccaagacac
     2461 cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga tgttccatac
     2521 caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga ctgtccttga
     2581 cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa tccgcgattc
     2641 ctgaacgcag gtaagccaaa tctagatctt gattacggtg tggtgactgg acaaggtatt
     2701 tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg agaatttttt
     2761 cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca actcctgccc
     2821 cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt aacattcttt
     2881 tctctttcta ttggccgaca aaaaagacgg caacgttacg gttaccatcc attataccat
     2941 gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca gagggagctt
     3001 aagaagttac caccgtcctc tagcgcctta tccgaatcaa agttaaggtt gatattttta
     3061 aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttaaggt tttagtgaaa
     3121 tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat gatgatattg
     3181 atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc ttcaacaatc
     3241 ttgcggatat cttcttctgt cagatttccc ttgctttctt tagctttggc gagtcctgac
     3301 ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt gtccttgttt
     3361 tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt attggcttgc
     3421 ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc actctcacct
     3481 gtaactggaa tgggtgctgc tacagtgatt ttggcgtgtt ccacacccaa agttacggct
     3541 gcatttcggt acatatcctg agttacctta gtgatgtttt caggtgtttc aatcttgacc
     3601 tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa ctgtaagcta
     3661 gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt cttgagttct
     3721 ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt ttggtcttca
     3781 gatagggaag aacctaggac atattcaggt tggacatagg tttcatcgat aactttttga
     3841 acatctgttg ctgcatggac gctattcata gctgttactg cccacaagat cgcagcgcta
     3901 gtcagaaaga gtttctttct catagggaat ttcctccttt acttctttag agtaatatat
     3961 ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg aaaagagagt
     4021 gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat agtttcctcc
     4081 atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac tataagtctt
     4141 tccagtccta ttaccaagca agggggcaac agtctcacga gagtactgtt tggctagagc
     4201 caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc caaaattata
     4261 ggcttgaaca gctgtccaga tatctacacc cttcttctgc gccagataga gattgcctgt
     4321 cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt tggtggaacc
     4381 acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt cagtataaat
     4441 catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaata tttctcgcac
     4501 catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag ctttatagcc
     4561 agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca ttatttactt
     4621 tggatatcct cgatattttt gattaagata gagtaggttc cattttcgtt ttggataaac
     4681 tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat tccatttgat
     4741 aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat ttcatcaaat
     4801 tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg agccgtcaga
     4861 ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct ttcttctagg
     4921 ttgttgaaaa tagctgattt gaccttggat tgaaattgaa aatcatctgt gttaaaagat
     4981 tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg agaaatctta
     5041 ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt gtacttgatt
     5101 cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc ctcgtcagca
     5161 cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc aacttctcct
     5221 ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg ttctacacct
     5281 tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga aatgctaaac
     5341 tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc tgtaatatga
     5401 ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga atacacatgt
     5461 tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa cttatctgct
     5521 aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt aatataaatg
     5581 tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt tgactgcact
     5641 tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa tgatgagttc
     5701 agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg ctgctccgat
     5761 acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat ttttatttag
     5821 ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta caaccttagt
     5881 cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga aatcagggtc
     5941 ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag catattcctt
     6001 gaaggctgga tccaaaactt ccttgaagga aactgcctta gccgccacaa catgctctaa
     6061 aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa gttcttcgtc
     6121 attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg ttgttgttgt
     6181 gatatgagcg tatggaactg ggcttggatg aaggccagcc gcaaccaagc cagcgatatg
     6241 ggccatgtcc accatgagct tcgcaccgac agcatctgcg atttcacgga attttgaaaa
     6301 atcgataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt ttacttcttg
     6361 ggcttgtttc aagatagcat caaagtctaa gagttccgtt ttaggatcaa cactataaga
     6421 aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca aatgaccacc
     6481 tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca tgtaagccgc
     6541 acagttagct tggcttcctg aatgtggttg aacattggca aatttagcac cgaaaatttc
     6601 ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc caccataata
     6661 acggcgtcct gggtaaccct cggcatattt gtttgtcaag atagaccctt gagctgccat
     6721 aacagccttg gaaactacgt tttccgaagc aatcaactcg atattatttt gttggcgttc
     6781 ttcttcttta gcaatagcat tccagagatc agcatcatat gctttaaaat catctttgtc
     6841 aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat tttacaataa
     6901 gaaaataaac taaaagatgc gaataaaccg tttctgcact ttatcacaag tataaccaac
     6961 tttttcataa aatgcatgag cacccagacg atgattggca gaatttaagc ggataaaccc
     7021 ataaccacat cttttggctt cttgttccaa cccttgtagt aaacttttac cgataccttg
     7081 accttgcgct tgaggtgaaa ctgctaaagc taagatatta aatcctgctt tggaatagag
     7141 tgattcgtaa acttcagcgt ggacatatcc aagtaagaca tgattagctg catcctcata
     7201 gccaagtagg aaatgatggg aatcctgaga cagtctagct agttggctag ccgtttcctc
     7261 tggactaaaa gtataaccca aagcctcttg gttgatgtca catatcgctt tcacatctgt
     7321 ttcttgcaaa tctcttagca tttcaagcct cctcaaaaga aatctctggc aaccgagcaa
     7381 gaatatcttc tcgtttaatt gcgccttggc gtaagatttt caccttgtct ccagacaaat
     7441 ccacaatagt tgaatcctgt ccagttagaa aagcatcgtc ttccagaccc agaacctctt
     7501 ggtcaaaatc cttcagaatt tgttcaaagg ttacaccact tgcctgacct gagatattgg
     7561 cagacggccc aatcaaggga cctgtctctc gaattaaatc cagtgtgata gggtgactgg
     7621 gcatccgaaa tccaatagtt gcaaggtcag aatttaccca atagggaact cggtcattgg
     7681 cttcgagaat aatggtcaag ggacctggca aaaaggtctc tacaagtttt tgtagataag
     7741 ctggctgatt ctttgaaaag tgcaagatgt cctcgaaaga ggcgatattg agattgagtg
     7801 ccttatctct aggacgacgt ttgagttggt aaacatggtc aactgctttt tcatctaagg
     7861 ccttggaaaa aagaccataa acagtctctg taggtagaac gacagctcca ccattttcca
     7921 actcttgtct aatcctgtcc atcatcaacc acaaccatcc tattttgacc aaattggtct
     7981 ttgagtgttc gaactctttt ttcaggaaga tgttttctaa aaagttcggg aacactttga
     8041 ccttgcttgt atccaatttc aaggtaaatc ttaccaccat ctttgagata gtcttttgca
     8101 tcttccgcaa ttctacagta aatagctagg ccatcctcgt ctgcaaagag agctagatga
     8161 ggctccgaat acaagacatt caagcctacc tctgactcat cttcacgaga gatatagggt
     8221 ggattggaaa caattatatc atatttttca gaaatttctg taaaacagtc agatttttta
     8281 aaaaatattt gaagattttg atttttagca ttttcgctag ctaaatctaa agcctcttga
     8341 gaaacatctg ctgctgtcac tgaccaatct ggtctatttt ttgctagagc gagagcaata
     8401 gctccactac ctgttccaat atccagaact gaaagattcg tctcaagatt ttcagttaga
     8461 ataagctcca ctaactcctc tgtttctgga cgaggaatca aaacccgttc atccaccttt
     8521 aaatgcattc cataaaaatc tgcctgtcca atgatgtact gagctggctt gtgagctgct
     8581 agttgctggt aaatatcttc tacaaattgt ttttcttcct ctgttgtcac ctcctgctgg
     8641 agggcaaaaa taaagtctgt aaaagataga tttttcagac tacgatagac aaaagagagg
     8701 ctttccgctt cctctccttg tcttatcaac tcttcttcaa aatttgaaaa taattgagct
     8761 aatttcatta tttgtttaat tcttctagtt tttgtgtttg gtcataaagc accaaggcat
     8821 ccacaacttc gtccaattta ccagacaaaa tcgtatctag tttttggagg gtcaagccga
     8881 tacggtggtc tgtgacacgg ttttgtggga agttataagt tcggatccgt tctgaacggt
     8941 caccagtacc gattgtcgac ttacgctcag cgtcttgttc atcctgagca atctgagcaa
     9001 agtggtcagc gacgcgtgca cggataatct tcatagcctt ctcgcggttc ttctgctggg
     9061 tacgttcttc ctgcatctca accttgatat tggttggcaa gtgaacgata cgaacggcag
     9121 tcgcaacctt attgacgttc tgtccaccag caccagaggc gtgatagatg tcgacacgaa
     9181 ggtcttttgg atcaatgtcg tattcaacct cttcaacttc tggcataaca agaactgtcg
     9241 ctgtcgaagt atgaacacgg ccttggcttt ctgtcacagg aacacgttgc acacggtggg
     9301 cacctgattc atacttaagc ttagagtata cagactgacc tgaaaccata gcaaccactt
     9361 ctttaaaacc accgacacca ttcatagagg cttccatgac ttcaaagcgc caaccttggg
     9421 cttccgcata cttttggtac atagttagca aatctccagc gaaaagtgcc gcttcgtctc
     9481 caccagctgc tccacggatt tcaaggatga tattcttgtc atcgtttgga tcctttggaa
     9541 ggagcaaaat tttcagtttt tcttcatatt cttctttttc agccttggca tctttgagtt
     9601 cttgcttggc caattcttcc aagtccgcat ctccgcctga ttccttaatc atctcttcgg
     9661 catcgacgat attttgaagg acttgtttat actcacggta ggctattacg gtgtcacgat
     9721 tggaagcttc ttcttttgaa agctccataa aacgcttggt gtctgaaacg acatcagggt
     9781 cactcagcaa ttctcctagt tcttcataac ggtcttctac agcttgtagt tgatcataga
     9841 tgttcatttt ttctccttat ttctcaattg ttaaatcata gattgctact acttcattct
     9901 cggatatttc cccagtttct ttaaatccat aactgaggta acaaaatctt gcctgttcat
     9961 tttctggttc ataagacaac caaagtttat tgcttaaacc tgctggcgct gttcgaacat
    10021 agtctagtac tttatccata attggtttaa aatatccttg attttgaaaa ttcttatcaa
    10081 tcataaaacg aaatagtaaa taatttccac tactaattcc gatcttttta tcataagcta
    10141 tcatcacaaa acctataatt gcatcattat cataaactgc caatggagct acaaaatctc
    10201 catttttagt gtagacgtat gcttcagcta aactaattgc gttggttgca atgaattgtt
    10261 tttgatattc cttgacatcc aaatttaaaa catcaaaata attttccatt gtaacatctc
    10321 ttagttcaat tgtcatagtt ttgctccttg ttagaggtta tcattggcgc aaaataatgt
    10381 ttacggcaaa ccgagatata ggtttcatta ccaccaatct ggatctgttc tccatcgtaa
    10441 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10501 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10561 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10621 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaaa
    10681 acacagtaag gtttttctgg taggtctcgg atatagccaa agatatccgt tgtttcctca
    10741 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10801 gtatccagag ccgaggtcat aatcacaaca ccttttcctt gctcctcgta gttataggcc
    10861 actttgagaa tctcaatcgt tttaccagag ttcatggtcc cataacgata gtacaactgt
    10921 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10981 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    11041 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    11101 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    11161 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    11221 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    11281 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    11341 aatagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    11401 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    11461 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11521 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11581 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11641 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11701 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11761 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11821 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11881 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11941 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aaactcctta
    12001 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    12061 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    12121 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    12181 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    12241 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    12301 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    12361 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    12421 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12481 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12541 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12601 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12661 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12721 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12781 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12841 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12901 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12961 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    13021 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    13081 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    13141 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    13201 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    13261 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    13321 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    13381 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    13441 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13501 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13561 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13621 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13681 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13741 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13801 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13861 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13921 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13981 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    14041 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    14101 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    14161 taattttctt agtttccttg gtcatcttca tctcttcgta agtgtaatca ttgtcagtga
    14221 agacatcgat ttgtggaaga gcattgaagg cgataggata atgtttcttg tcaccacctg
    14281 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acctcacgaa
    14341 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    14401 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    14461 ggattgttga acaattaggg caggcaatga ttccgttgtg agcatcaagt gcatgagcat
    14521 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcta
    14581 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14641 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14701 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14761 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14821 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14881 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatta
    14941 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    15001 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    15061 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    15121 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactcttgta ttcaagagtt
    15181 tccctataca tatcatgcta attgccggga ttgaaccggc gacctcatcc ttaccatgga
    15241 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactataa tcagaaaaac
    15301 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    15361 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgctccaa
    15421 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15481 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15541 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15601 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15661 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15721 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15781 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15841 caatatctgc aacatcacga atagttaatt ttttcatctt ttctcctttg gcggttatcc
    15901 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgattcatt caaccttact
    15961 agtatagcac aatagcctgc tttatgctat acttaaagca tgaaaattcc tattcaaaaa
    16021 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    16081 attctctcac gactagtcat ttatcaacta agtcatcagg aactccttgc tacggccttg
    16141 gcaaatatta tcggtatctt atttgccttt atcacaaatg atacgattgt atttaagcaa
    16201 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    16261 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat catagggcaa
    16321 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    16381 attattatca tcaattatat cttgagcaag gtctatattt ttagaaaata atgctccatt
    16441 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16501 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16561 cttgctgtcg gtgttgtcat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16621 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt cgaacgtatc
    16681 gctcaacttt cttggcatgg agtcggctat ggtaactttt taagtgctat tatcaatttt
    16741 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16801 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16861 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16921 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgataaga
    16981 taaggcatct taatattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    17041 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    17101 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    17161 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    17221 tttaccccaa attcctgaca taaatcataa cattccacat cattgtcaaa caagacctca
    17281 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    17341 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    17401 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    17461 ttttcgaaaa tttggtctat ataaggatct ccaaagtcca aggcaaaaat aggcacacta
    17521 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17581 atttcatctg cccaatagtt taagagcgct tcttcctgat accagtcctt aatgaccaaa
    17641 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17701 tggggctcca aaatcaagca aatacactgt tcaattccgt ctgcttccat ttgaccgatc
    17761 acatctggaa taaagggact ggaaaactta ttagcaaagt agacactgta ttcattcccc
    17821 agcctagctt ctaccaaggc aacctcttga cgggtaattt tttgcagagg cgtgcctcca
    17881 attcgtacat aattatcata gagagtctga atctcgtggt cttggggtct catcccacga
    17941 cgaatatttg tgaaaaaatc agctacacct tcaaaggtaa tctcttctgg tgaaccgaag
    18001 gtcatcatta aaattgcttt tttcatgact gcttccttgt aatgttttta tcaagtttat
    18061 tttatcatta attcatcgat aagtaaacgc tagcataggg acattctcaa tcttctgtct
    18121 tttgtttttc tcttctttct atgatacaat ggaaaaaata aattcaaaag gagtttttta
    18181 tgacttatcc aaatctcttg gaccgcttct taacctacgt taaggtcaac acgcgctctg
    18241 atgaacactc tactactact ccaagtacac agagtcaggt tgacttcgca acaaatgtcc
    18301 taattcctga aatgaaacgt gttggactgc aaaatgttta ctatctaccg aatggttttg
    18361 ctattggaac cttgccagcc aacgatccgt ctttaacacg taagattggt tttatatcgc
    18421 acatggatac tgctgatttt aatgctgaag gagtcaatcc acaggtaatt gaaaactacg
    18481 atggtggtgt gattgaacta gggaattctg gtttcaaact cgatccagct gacttcaaga
    18541 gtcttgaaaa atatccagga caaacgctca tcacaacaga tggaacaagc ttgctaggtg
    18601 ctgatgacaa gtcaggaatt gctgaaatta tgacagccat tgaatatcta actgctcatc
    18661 ctgaaattaa gcactgtgag attcgtgttg gttttggtcc agatgaagaa atcggtgttg
    18721 gtgccaataa atttgatgca gaagattttg atgtggattt tgcctacact gttgatggtg
    18781 gtccactagg tgaacttcag tacgagactt tctcagccgc tggtgctgaa ttgcatttcc
    18841 aaggccgtaa tgtccaccct ggtactgcca aagggcagat ggtcaatgcc cttcagctag
    18901 caattgattt tcataatcaa cttccagaaa atgaccgacc tgagttaact gaaggttacc
    18961 aaggttttta ccatctaatg gatgtgacag gtagtgttga ggaggcgcgt gcaagctaca
    19021 tcattcgtga ttttgaaaaa gatgcctttg aagcgcgtaa agcatccatg caatctatcg
    19081 ctgataagat gaatgaagaa cttgggagca accgtgtcac tctcaacttg acagaccagt
    19141 actacaatat gaaagaagtc attgaaaaag atatgactcc aattaccatt gctaaagccg
    19201 ttatggaaga tctaggtatc acgcctatta tcgaaccaat ccgaggtgga acagacggct
    19261 ctaagatttc ctttatggga atcccaactc cgaatatctt tgcaggtggc gaaaatatgc
    19321 acggacgttt tgaatacgtt agccttcaga ctatggaacg tgcagttgat accatcattg
    19381 gcatcgtacg tagcttataa aagctaaaaa gacgaggtag ctcagctact tcgcctttct
    19441 ttttattcta ctggtttttc ttgatttcca gtagttgtag aagattctgt tgttttattt
    19501 tctgaagttg attcagcagg tttagaatct cttgtattgc ttggtttgtt ttcgtcgcta
    19561 gcagtttcaa tgttagattc tgcagttgcg tttggttggt tctcagcact ggtgttatca
    19621 ccatttgctt cagcatttct tgctggactt gtttcttcac ttgcgctagc ttttgactgg
    19681 atttgatgat tcaaaactag aatagctttt gtcgattcaa gtaaagctgt tttgtcttta
    19741 ctcttagcag aaagttgatc taataatgca tccaccttat caaagtccgc atcagatcca
    19801 ttattacttt ctaaataaga gtgaagcgac atgagaatat cgtagagttt ttgatagagt
    19861 acaagtgtct gaggatcttg ctcagcattt tccttttctt gttgaagggc gctagcgata
    19921 cgagtcaaaa catcttttac ctgactgttt acttcatcca agtctgcatc agccttgttt
    19981 gtggcagctt ttagattttc tacttcttct gccaaggatt gtctgattcc ttcttcatgg
    20041 atttgttcca agagttgatt tgccttgttc aaaagacttt ctacttcttc cttgctatct
    20101 gtcgcagatt attggttgct atctaccatg tactcctaaa acaggagagt tataatccaa
    20161 gattacaagg ccttacagaa ataagaaatc cagataagac aatgttcgtc caagacgcta
    20221 ttcgcttcgc acagcagcac ggattcaata tgctttaatt ttaaagttta ggtgtcaaga
    20281 cctcttttta gtgtgcccaa aatttagaga agtaatcaat caactaactt ttattttttt
    20341 caaactttca gtaaactgac ctaaagctaa ctcaatctgt ctttgtagat gcttctgcta
    20401 tcagctagaa gttgatctac ttttgccaag actgccttct catcaaaagt tccaggttga
    20461 tagttggatt gcagggatgg aatcttgttt ttcaaagccg cttcatatcc cttagtttga
    20521 accttgatgt agtgattgtg gtcgccacga ggaatcacaa aaccttctga atcttcactt
    20581 ataattcgat tggcatcaaa accatgacca tcttcttcct catggtggac atgtagtgac
    20641 ggattactta atacagaact agaagaactt cctacctttt ccgtgttaga gtgtgatggg
    20701 ggattgttaa gagatgactt aggaatatag tgatagtgac cccatgtctt actatataag
    20761 catcacctgt atctctgaca atatcattag ggttaaagac ataaccatca tctgctgcag
    20821 aaacaccatt attcggtgtc accgacaaag attgactgag agctgtagta ttccctgata
    20881 attatacttt tgcagctgct aattcacctg ccgacaagtc actctcagga atgaaatgat
    20941 agtgaccacc atgtggtact atagtagatt gaaatagaat atgagcaaat tgataagggg
    21001 attttaaagt aatttctaac aatgatttag aaactatgat gtgctattct aaattcaact
    21061 cactatatat aaccatcatc ggtagtataa cgtccctgta attttgctac agatacttct
    21121 gcactagctc ctttatcgtc tttaccatgt tcttgttttt ggcgattgat ttcatctttt
    21181 attcgtacat tttctgcatg agcttgatct ttaaggtaaa cataatactt tccatctacc
    21241 ttaatactat atcctccctt aacctaactg acgatatctt gatctttcgg ctgatagttg
    21301 ggggctttca ttaatagctc ttcactaaag agcgcatcaa aaggaacttt accattatag
    21361 tagcgataat gatcgccatg agaagttaca taaccttgat ctgtaatctt aataacaatt
    21421 tgttttgctt gaattccttc tttttgacta acctagtctg gagtcaaatt ttcagtcttc
    21481 ttagtgtctt tattactgtt tacatatgaa acacgatttt tatctgtatt ggcctgttag
    21541 ctatgttggt tcagagtata aacacacaga cttaaggaaa ggataacaac agatccagct
    21601 gctatatatt tctttttaaa tttcataatt acctcatttc tata
//
LOCUS       DAVKXA010000037        20291 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKXA010000037 DAVKXA010000000
VERSION     DAVKXA010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.037"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            114..278
                     /locus_tag="VW883_001474"
     CDS             114..278
                     /locus_tag="VW883_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0274595.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            362..928
                     /gene="amaP"
                     /locus_tag="VW883_001475"
     CDS             362..928
                     /gene="amaP"
                     /locus_tag="VW883_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0274596.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            940..1110
                     /locus_tag="VW883_001476"
     CDS             940..1110
                     /locus_tag="VW883_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0274597.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1149..1757
                     /locus_tag="VW883_001477"
     CDS             1149..1757
                     /locus_tag="VW883_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0274598.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1788..1991
                     /locus_tag="VW883_001478"
     CDS             1788..1991
                     /locus_tag="VW883_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0274599.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2101..2373)
                     /locus_tag="VW883_001479"
                     /pseudo
     CDS             complement(2101..2373)
                     /locus_tag="VW883_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2577..2864
                     /locus_tag="VW883_001480"
     CDS             2577..2864
                     /locus_tag="VW883_001480"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0274600.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3142..3912)
                     /locus_tag="VW883_001481"
     CDS             complement(3142..3912)
                     /locus_tag="VW883_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0274601.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3927..4765)
                     /locus_tag="VW883_001482"
                     /pseudo
     CDS             complement(3927..4765)
                     /locus_tag="VW883_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
     gene            complement(4762..6237)
                     /locus_tag="VW883_001483"
     CDS             complement(4762..6237)
                     /locus_tag="VW883_001483"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0274602.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKTYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6561..7916)
                     /locus_tag="VW883_001484"
     CDS             complement(6561..7916)
                     /locus_tag="VW883_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0274603.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGCFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7926..8243)
                     /locus_tag="VW883_001485"
     CDS             complement(7926..8243)
                     /locus_tag="VW883_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0274604.1"
                     /translation="MDESNLESVMGLIMYGGDAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8260..8577)
                     /locus_tag="VW883_001486"
     CDS             complement(8260..8577)
                     /locus_tag="VW883_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0274605.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8592..9488)
                     /locus_tag="VW883_001487"
     CDS             complement(8592..9488)
                     /locus_tag="VW883_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0274606.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9491..10753)
                     /locus_tag="VW883_001488"
     CDS             complement(9491..10753)
                     /locus_tag="VW883_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0274607.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11033..12211
                     /locus_tag="VW883_001489"
     CDS             11033..12211
                     /locus_tag="VW883_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0274608.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDSNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12439..12885)
                     /locus_tag="VW883_001490"
     CDS             complement(12439..12885)
                     /locus_tag="VW883_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274609.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLKDSNLHIGRFFINPQKQGQGLGSQTLRKFVSLAFE
                     NEDIDNISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            12955..13614
                     /locus_tag="VW883_001491"
     CDS             12955..13614
                     /locus_tag="VW883_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0274610.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLKKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(13586..14362)
                     /locus_tag="VW883_001492"
     CDS             complement(13586..14362)
                     /locus_tag="VW883_001492"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0274611.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14355..15578)
                     /gene="trpB"
                     /locus_tag="VW883_001493"
     CDS             complement(14355..15578)
                     /gene="trpB"
                     /locus_tag="VW883_001493"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0274612.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(15556..16155)
                     /locus_tag="VW883_001494"
     CDS             complement(15556..16155)
                     /locus_tag="VW883_001494"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0274613.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(16142..16909)
                     /gene="trpC"
                     /locus_tag="VW883_001495"
     CDS             complement(16142..16909)
                     /gene="trpC"
                     /locus_tag="VW883_001495"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0274614.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(16906..17910)
                     /gene="trpD"
                     /locus_tag="VW883_001496"
     CDS             complement(16906..17910)
                     /gene="trpD"
                     /locus_tag="VW883_001496"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0274615.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(17921..18487)
                     /locus_tag="VW883_001497"
     CDS             complement(17921..18487)
                     /locus_tag="VW883_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0274616.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(18484..19845)
                     /gene="trpE"
                     /locus_tag="VW883_001498"
     CDS             complement(18484..19845)
                     /gene="trpE"
                     /locus_tag="VW883_001498"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0274617.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
BASE COUNT         6325 a         4408 c         3468 g         6090 t
ORIGIN      
        1 aatttgattt tttgatatta aaataaaaaa ggagggtagg cagtgttgtg atcaattatt
       61 gctggaggtc ttattggtct cttgacaggt aaaatcacta aaaaagtagt tctatgggaa
      121 tcatcgcaaa tgtattcgct ggtttagtcg gggcatatgc aggacaatct cttttaggta
      181 gttggggtcc atcaatcgct ggaatggctt tgctcccatc tattgtaggt gcagcgattg
      241 tgattactgt agtgtcattc tttacaggta gaaagtaaac ttttcgccag taaagttagc
      301 aaactatttt taaatcaatg acgggaaaaa tagtttaaat gttaaatcga aaggattgta
      361 tatgtcaaaa gcaaagaaaa tatgtttcat tattttctgt attttaatct tgacaatttt
      421 ccttcctgtt ttgatagatt atcatcaagt tagtgatcta ggtattcatc tacttagctg
      481 gagacagaac tccgtagttg aattctatct tgctagatat gtcttttggg ggacagtggt
      541 tctatcaact ttagttttat tatccatttt agttgtgatg ttttatccta aacgttactt
      601 ggaaatccaa cttgaaacta aaaacgatac attaaaatta aagaattcgg caatcgaagg
      661 ttttgttaga agtttggtga gtgatcatag attgatcaag aacccaactg ttcatgtaaa
      721 tttacgaaaa aataaatgtt tcgttcatgt agaaggtaaa attcttcctt cagacaacat
      781 cgctgacaga tgccaaataa ttcaaaatga aataactaat ggattgaagc agttttttgg
      841 tattgagcgt caagtaaaac ttgaagttgc agtaaaaaat taccaaccaa aacctcaaaa
      901 caaaaagact gttagtcgtg tgaagtaagg aagtaaaaaa tggaatggct taaacaatat
      961 cgatatccaa ttatcgctgg tctcataggc gtatttctgg cttgtttgat tgtctccttt
     1021 ggcttcttca aaacaatatt tgtattgatt ttaggagcac tgggagttgc agctggatta
     1081 tatatcgaaa aaaactatat agataaataa aaaaataaaa attactaatt taattaaagg
     1141 agtttcatat gtcaaacgaa aaaaacacaa atactaacgt agaaaagaaa gatgctactg
     1201 ttgtagctca cgaaatcaaa ggggaactta cttacgaaga taaagttatc caaaaaatca
     1261 ttggtctttc actagaaaac gtttcaggtc ttttgggaat cgatggtggt ttcttctcaa
     1321 atcttaaaga aaaaatcgtt aacagcgatg acgtaacaag tggtgttaac gtagaagttg
     1381 gtaaaacaca agttgcagtt gacttaaacg ttattgttga gtaccaaaaa aatgttccag
     1441 ctttatattc agaaatcaga gaaatcgtat cttcagaagt tgctaaaatg actgacttgg
     1501 aaattgttga aatcaacgta aacgttgtcg acatcaaaac taaagaacag catgaagcag
     1561 actcagtaag ccttcaagat cgcgtatctg acgttgctga atcaacagga gaattcactt
     1621 cagaacaatt cgaaaaagct aaatctggtc ttggatctgg tttctcaact gttcaagaaa
     1681 aagttagcga aggtgtagaa gctgttaaag gggcagcaaa tggtgtagta tctcacgaaa
     1741 acactcgtgt aaactaagat aaaataaata taacaggaga aattatcatg tcagtagaag
     1801 aaaaattaaa tcaagctaaa ggttctatta aagaaggtgt tggaaaagcc atcggtgatg
     1861 aaaaaatgga aaaagaagga gcggctgaaa aagttgtttc taaagttaaa gaagttgccg
     1921 aagacgctaa agacgctgta gaaggtgctg tagaaggtgt taaaaacatg ttgagtggcg
     1981 acgataaata aggttaaaag ttactttatc tttttggtaa cattagtcaa aagagtctga
     2041 gtcgagatga ttctcagaaa acaaaaagct agagattccc aattgcggaa ctctagcttt
     2101 ttaattttgc ctctttctct tattatattt cagcaggttg ttggccatga gtatgaatcc
     2161 catgtcaatt ctcacttgac gcttacctct cagatgacat ctcttataac ccaaacaaac
     2221 ctttatctgc ccaaagacag atttcatatc aatcttacgt ttagcgaaaa tttgtctacc
     2281 cttggaagat aaaagtgcct gatattcttt agtttttaaa cactggtaac gttcattcat
     2341 atacagtctc ttttgagggg ctgattcagg ttcataatcg cagtcaacat tgatttcaag
     2401 gctgtttgct ttctatctcc cctttttcat gatatatttt cgtacaggtg cttcaatagt
     2461 ttctatagta aaatgaacca aaaatagtac acgttgcggt ataatgttct tatggcatat
     2521 tcattagatt ttcgtaaaaa gttctctcct atttgtgagc gaacaggtat agtcaattga
     2581 ttgtcagttt gaagaccaag agtcgtaagg caaaggatat ggcagaatcc atccaagggt
     2641 ggctggcaca atttctagtg aacctcttta aatctattac gtttgactgt ggaaaagagt
     2701 tttcaaaatg gaaagatatt tccaatcatc acgatagtga gagctttttt gcgaatctag
     2761 gatgtccaag acagcggtgt ctcaacgaac attcaaatag acttttaagg tgtcatgact
     2821 tgccaaagca gacagatttc aacgaagtca gtcaagaatt ttaggctggg taaaaactca
     2881 atttcaggag aaaatgaaat aaatattccc acaataaaat gcatagtatc aaagtttttc
     2941 caacacctga tattatgcat tttttaattt taaagacttt ttcccagcct caagaaatca
     3001 catcccacct aaatcctttg gataccaaat acctcatcag gtattttctg agttggtaag
     3061 actgtctagc ttaatttgac aaatggaggg cgttaaatcc agtttttaca ggaagtctat
     3121 ttaaatattt tcacactgac cttacaaaat atgaaataaa ttatataaag tcattcccat
     3181 gacaaagaat aacatccctt taaaacagta tcttacccaa ttttcaggta agacttttga
     3241 tacaaccgtc cccaataccc ctccgcatat agaagcaaga aaaataactg gaacaggtgc
     3301 taaatgatac tgatttaaac ctgtaaccac aacaattgta gccaaatgag acaactggga
     3361 aaagaaaata attgcaagag aatacatcgt tgcttctttt atcgaaatag aaaaaaacac
     3421 catcaataaa gatacattga gcggaccacc accaatccct aaaaaactag aaatcaagcc
     3481 caatagaaga ccacaaatca tatagaatcc tatcttatca aattgataag tttttttaaa
     3541 atctgttaaa acaaatgata caagtagcat cacaaatagt aaaatcattt gaacaatgga
     3601 tactagccgt actgataatt gagataacaa aacttgaaaa ataagatgac ctagaaaccc
     3661 tcctaaaaca gaagaaaagg ataccgtaaa aatcaatctc cattttatct ctttactttg
     3721 tgaaaatctt ttggttgttg aaataatcgc cattataaaa acagagaaac tagaataaaa
     3781 agcaatatca ctgaccgaat ggtatccaaa actatccata agtggcttaa ttataattcc
     3841 accacccatg cctgatatag aacccaatcc actagctatt ataatgatta gaaaataaat
     3901 aatctcaacc actttttaag tccatcctat tctttcaaac atctaaaacc tagatggcta
     3961 ctagtggaag tagaaataca tccatttcta gcagctactc ggtatcgatt acaataagaa
     4021 caatgacata aaaaggaacc tcctctgata gcatactcct catcttgtat cccatatttt
     4081 ggtaactcat agtcatcttc attaaaacta gctaataagg tatatctcgg attgcgacac
     4141 cattcccaat catttgatat agaccaaaat cattaggtaa aaattcatag acaggagccg
     4201 ttcctataaa tccatctaag gcagtatttt cataaggaaa tcttccttgc caagtattgg
     4261 catgataata tccaccttct aaaagagtat ctccccaagg atattcagat tgtcttcctc
     4321 ctctagcagc atattcccac tgtgcttcag tcggtaaaga cattccgctc caattacaga
     4381 aagccaatgc atcttctaaa gcaacatgaa ctactggatg gtcttctaaa cccactagat
     4441 tactgttctc accgtaggga tgtttccagc aagcgttcga aacttgtaac caccacggag
     4501 ccccagcagg atgaggatat ccctcccttt ctgcctccgg aacgaacaat ataaaaacaa
     4561 aagaccactc ttgtcgctca gctagtgttt tatagcctgt ttctttcaca aattgagcaa
     4621 attcttgatt cgtaactgga gtatccgcaa tggaaaaatc ctttacacta acagcgactt
     4681 gaggaccttc aaaatcatct aaaaagccct cttcagaatt tgttcccatc ataaatgtcc
     4741 cacccttgat ttttttcatt ttcatgattg actatccccc gttttcgtta gagttggcgt
     4801 tattttagaa agttcaacag gaactaactc ttcatccaca acaaaacctt cttctctata
     4861 tctaagaaag tctactaatt ttttcttcat ctgacgaaca ataggttgat atttttcact
     4921 tggatacaaa tcattcattt catgcggatc ttttttcata tcaaataact gataatgatt
     4981 taaaacagga aaccagataa atttccactg gtctgtcaaa atatattgac tagaatcttt
     5041 tcctaaagca tgttcaccat gaaattctgt tcgccacccc tcgtactgtc caaataataa
     5101 attcttaaca ctccgtccat ctagttcatc tgtagtagtt cctcctgcca aatccacgag
     5161 tgaaggaaaa atatcttgaa ttttcactaa ttgcttgatt gttcccctat taccagctat
     5221 caatccagcc ggatcgtaaa taaacgaagg aatgtggata cttccctgat aaggatatcc
     5281 ctttctaaac agataatgtt caccaagctg atctccatga tccgaaacaa accagataat
     5341 cgtatcttta tcatgacgaa attcttttag ggcagtcaaa aagcgactaa tttgatggtc
     5401 tatatgagta atcaatccaa aataagcagc aaccattctt ctttgatcat cttcctttaa
     5461 tttccctctt aaagcataaa tagacggaat ttgcttttct aatacttccc aattcccgat
     5521 atgcaaatcg agaaattgag gcaagcgttc catatacata tcaaaatagt attttggggg
     5581 atttaatgga gcatgtggtt tttcaaaaga cattttgaga aaaaaaggaa ccgttggatc
     5641 tcttctttgt aaaaatgaaa tagactcact cacaacccag tttgttggat gtaacttctc
     5701 atctttatcc caaggtctag cttcccagga attacaatcc attccgtcat caatcaaatc
     5761 aacatcataa ccaactttac cctttaaaaa ggctagatag tcactagcat aatcaaattg
     5821 acttccataa gtcttatcat actttctatc aacatgtaga tacccatcgt gaagtaatac
     5881 atgatcaaac ccaagtctct gtctggaagg aaaaacatgc atcttaccaa tacactctgt
     5941 ttgataaccc atatctttaa agacttttgg aagagtatta gtaaaattcc aaggcacctc
     6001 atcttgataa ccaacacgtc cacttttatc ttggtctaag ccagtcaata aagctgccct
     6061 agcaggaacg caagaaggaa ctggagaata ggcattttca aaattataac ctacactagc
     6121 catcatatct aatgttggag tgctaactag cttatcctta ctattcaagg ataaggcgtc
     6181 tgctctcatt tgatctacaa caatcaaaat aatatttggt tgttttgtct gaaccataaa
     6241 atctcctttc taatatggca aaagaggcac aagaagatat ctacctttac tgcacccctt
     6301 tctatatcaa tctctctata taaagcaata acattcttgt tatgttttat agaaaaatga
     6361 actaaaatat gactaaatcg attaggaaat tcaaatcatt ttctagtact attttagaag
     6421 ttacagtgta ctattccaac ttcaataaac tataaacctt tgtctaataa caattttagt
     6481 ggagataaga aatcctacac ctaactcaat cttacacgta atctatttct attttatcac
     6541 aaaaaacgca agtaagacca ttaactcaat tcagttttat ctgccatttt cacaaatggg
     6601 aaataagtca agacactaat aatcaaacaa acaactgata agatgatggc acgccaatca
     6661 aatgctgtag agaagcaacc atataaaatt ggaggcatta cccaagtaac attttgtgta
     6721 acaggtgaaa caagacccca gcttgttgcc cagtaagcta ccgttgccat gaaaaccggg
     6781 ctaagtacaa atggtataaa tagcaaagga ttcaagacaa ctggtaaacc ataatttacc
     6841 ggctcaccaa tattaaacag aactggtgct agaccaagtt tagcaacttt tcgataatga
     6901 ctgtttcttg aaaaaattaa aatagcaagt accaatccta atcctccaaa ccagacaaac
     6961 gccccaaaag acccacttgt ccatatataa ggaatcggtt cacctttttg gaaagcatcc
     7021 agattcgcta acatagcaac tccaaacagc ccttccatga tgggagccaa tacatttcct
     7081 ccatggagac caaaaaacca gaataactta tttaaaaaga tcatcagaat aactgcaaag
     7141 aaactttgag acaaacctag taatggcgtt tgtaacacct tgtaaaccca atcaatcaat
     7201 aagtcattgc taagtaaatg gaaaacataa gtcaagatgg ctactatata catcgccata
     7261 aatcctggaa tgatagaagt gaacggctta gcaatcgcag ggggaactga atctggtaac
     7321 ttgattaccc agttcttttt cattacttta cagaaaataa tagaggctaa aaatccaatc
     7381 atcatggctg taaagtagcc tctggcatta atatggtttc ctggaatcac attcccaata
     7441 gttaccatca gatttttacc atcaaatgct agattatcaa ttccttgtaa gatttgatct
     7501 aatttcacat ctcctacatt tgccaaaggg aaactctttg taactgtact tccaatcgaa
     7561 atgacaaacg aagcaagcga taccaaacca gcagaaactg tatcaacctt ataaatctta
     7621 gcgatattca ctcccaagca atagatgaac aataaggaaa caattggtat acttcccttg
     7681 aataccaaat tattgatgtc aacaagccac tgaaaggttt tcgtaatact ttctaggtga
     7741 aattgttgtg gtaaatccac tagaaaagca tttaataaca aagcaatgga acctgtcata
     7801 ataacaggca tagtccccac aaatgaatca cgtaaagcaa ctaaaaactt ctgattccca
     7861 actttcattg caattggaga aagtttttct tgcattttat ccaacattgt attcatagca
     7921 aattcctaat ttttttcaaa tcgttcgtat acttctacca cttctttcgc caagtcaaca
     7981 aaggtcagac tcgtcattaa atgatcttgc gcgtgtacca tcaagaggct aattgatgtt
     8041 tcttccccct gtgcctcttt tgtcaacatt tctgtttgag ccttatgcgc ctgtaataag
     8101 gcagcattcg catcagctaa tcttcgattg gctttagaga aatccccttt ttttgctgcc
     8161 tgaatagcct ccatagcatt acttttggca tccccaccat acataattag ccccattaca
     8221 gattctaaat tactttcatc cataacattc tcctcaatct tagtctaata aactttcagc
     8281 taaatctaaa actttagaac cattcatcat tccgtaatct gtcatcggaa taaccgccac
     8341 aggaatctgt ctatctttta gtttttcttg aaagtcccct agtaaatagc gaacttgggg
     8401 gcctaaaagc aacacattta cttcttttgt tgctacaatt tcttctgctt caggagctgg
     8461 aactgcaaaa atttctgcat ccaacccctt atcttctgct gccttttgca tctttgtcac
     8521 tagcagactt gtactcatac ctgctgcaca tgctaacata attgttactt tagccatagc
     8581 ttactccttt atcacctatt tactgaccta gccaagcgag atactgtatg tctcactcct
     8641 ctaattgcct tgctcaatgc ataaatatta tcgactgttg ccagtccccc atatcctgcg
     8701 tcacctatat gttgaatatc aactccacaa attttatttc taagtgcaat ttccttaata
     8761 gtatctgtat cagatgtttc ttggctagta ccaatagcac tcaatacaag accaccctta
     8821 ctatgaacga gatcaacgac ttcacgcaac tcttggtcat gaaaggctgg aacggttcca
     8881 actgctggaa caagtatcac atccgcacct gcttccaaca attgctctgc gacagaaagc
     8941 tctgccacag gctcattcac tcctgccccg tgcatcttac ctgcaataat caaaccagaa
     9001 aagttttcct tagcagtttg aacagcctta atgatttctc gattgctaac tcctgttcca
     9061 ggatttccag tcaaacagac aaagtcaaaa cctaactcct ctattcgatt caatgtttca
     9121 acactagcaa cacgacctgc aacaatttcc tgtgtttcct ctagcatctt tgcagatggg
     9181 tcaatcggtt ccaaatttac accaattgga caagcaacaa gctggtgtaa gcgatgaata
     9241 acatcatcac ctgaactatc caaagcataa attttaggct caaaaacatc aacacaattc
     9301 aataaaatca tatcagctcc aaaagctcta gcaatttcag aattagttat atccccaaca
     9361 aatgtctcac gagtaactac attttcagat agaacaactc taccttcact tgctaaaata
     9421 ctttgtttta attcttcagc attcatctgt aatatctcag atggatttgc actaattaaa
     9481 cgtttcattc tcaatcctcc aataacttaa accgtttttc aatagctatt acaaatggta
     9541 aataaagtaa gacatccaaa acaatcaata caatttgtaa taatgaacca gaaatacttc
     9601 ctgtagcaag taaaccactt ataacaggtg gcatagtcca acctggatct gtataagtta
     9661 gcggaaccaa acctgatgcc attgctcccc acgctactag taagttaaac attggagcta
     9721 agataaatgg aactagtaac aaaatgttca aaacaatagg aacgccaaac attgctggtt
     9781 catttatatt aaataatcca ggtataacag ttataggtgc caaagttttt agttgtttac
     9841 tagctttctt cttatgtgct aaatatccta acgcaagaac taaacctatg gttgcaccac
     9901 cgccacctat gaatacaaaa ttatccataa atacgctagt aaaaatattt ggaagagttt
     9961 ctccagtttg ataagctact ttatttgcat ctagattagc taaccataac ggtttcataa
    10021 ctgcattaac aacatttcct ccgtgtaatc ctacaaacca aaaactacta ttaaggaaaa
    10081 ttaagataag aagaccaata acattatttc ctaaaagtcc aagtggacct cccaaagcta
    10141 cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc taaagttgca taaacaatca
    10201 accaaccaac aatagtcact gcaccaggaa taatggcact aaagctttta gatactgctg
    10261 gtggaacacc atccggcatt tttatctgta tattatgatt tataaaccat tggtagatat
    10321 agccattaat caatcctaaa atcatagcaa caaataaacc ttttgatgcc atgaaagcgg
    10381 taggcattcc tgctccagcc tctcctgtaa tgaaaggcgt aactgtaata aaagatgata
    10441 atgacacaat accagcagga ataccatcaa ctttgtattg tctagccata aagtaagcga
    10501 taccaaaact agctacaaga ccaagtaatc caaaactact atcaacaccc ttccataaat
    10561 agtcagcaac accaatatca cccagatatt tttcccatcc tggaatagga aaacttgcaa
    10621 taaccattag taatgaacct atcaacaata aaggtatagt tagagtaata ccgtctcgaa
    10681 tagaaaccaa cgctttatta ttacccaatc tagccgctac tggaagtaac ttttcttgta
    10741 ataatttttc cataaccttt tcctcttaaa tatattttat tatcaaaagt tatcatttat
    10801 ctttattttt tgacgtcaag ttgttatttg attatctttt gttatttata ttttacaact
    10861 ataagaaagc cttgtcaagg atttgtgtaa acatttgatt attttttatt atcaatatat
    10921 aataaaaaga gaccagtaag taatgaaaag cttaaaaaga ttaacatcta catttatcca
    10981 tagcaaaaaa tcataggatt ttaagaatct gacaactagg aagaaaacta atatgacctt
    11041 atctaagaaa caattacaac taagagctaa aatactggaa acagtttaca cattaggtcc
    11101 catttcacga attgaaatcg ctactaaaac aggaataaca cctgcaacaa ctagcagtat
    11161 cacaaatgat ctgattaaag aaaatattct cttagaactt ggtgaagacg aacacgatac
    11221 aagcgtaggg agaaaaaaaa tcctgctaga cattcaagct aaacgatttt actacattgg
    11281 ttgtgaacta tctgaaaaac atttcacttt tgctttagga gataatctag gaaatatctt
    11341 aaaggaagag aaagaaattg ttactaaaca gttaatccaa gaaaagggaa atcaactcat
    11401 taaccagaca ctaaagcaat tcttaaataa ctgctctgat tatgaaatag aagcaattgg
    11461 aatcgcgcta cctggtcgct atttagatga ttataaaata acaacaaaca atcctttatg
    11521 gcaacatatc gacttagaaa tgattcaatc ccactttgat aagcctttgt ttttctctaa
    11581 caatgttaac tgtatggcta taggtaaacg cctatttagt cgccaacaga atgactctaa
    11641 ttttgcttat tttcattttg ctagaggtat gcactgttct tatatctacg acggaaacat
    11701 ttatgggaaa ggaaatctaa tgattggaga aatagggcat acagttgttt catctgaggg
    11761 agaagaatgt agctgcgggc gcaagggatg cttacaaact tttgctggag aatcttggtt
    11821 aatcaaaaaa tcaaaaattc tatatcatca atctccctat tctctacttc ctagtttagt
    11881 caaaaatgcc gatgatattg atatccaagt tattttaacc gcttatcaat taggtgacac
    11941 tggaataatc acacttatcc atcaagcctt actctatctt agtcaaacca ttttaaatat
    12001 cagtatgatg attgactctc aaaaaatcta cctacatagt cctttactaa caaatcaaca
    12061 catcatccaa aaactatata gtgaaatgaa ctacaaaccc aaactgctct ataatcgcct
    12121 acctgaagtc attattgaac cttacaatga ttttacagcc gcacactcag ctattgcact
    12181 ttgtttgtat catacaattc tacattctta attttctatt acatttaata aataggctaa
    12241 aaagagggag tatatcataa aaagcgaata aacctgtttt ctgaaaatca gaattctgtt
    12301 ttgttcgctt tctttatatt tggaattata ctcctatctc ccatttttca taatgtatag
    12361 taaaatgaaa taataacagg acgaatcgat cgggacagtc aaatcgattt ctaacaatgt
    12421 tttagaagta gaggtgtact attctagttt caatccacta tattttcgta caggtgcttc
    12481 aaccatttga acgatttcaa atccttcttt ttggtaaaga ttctgagctc tttgatttgc
    12541 ctcgaagaca tttagagaaa tattatctat atcttcattt tcaaaggcca aactaacaaa
    12601 tttccttaaa gtctggctac ctaagccttg cccctgtttc tgggggttga taaaaaatct
    12661 cccgatatga agattgctgt cttttagcct gattttctgg ataaggccca caaactcttg
    12721 ttcatcaaag attgaaaata cttcttccaa ggcttgaagg gtcagtagaa aaggaatcct
    12781 tggtcccatc cattgttctt gaaaggattt gcctagggag ttggaccatt ggcatacaaa
    12841 ttgagcgttt tctatactca ccttttcttc aaaacgaatt gtcatctttt cctcaccatc
    12901 ttatctatgt ttctccatta tactatttct cccatttttt acgaatagat aagtatgatt
    12961 gatttttatt tttttctcgt cgggagcatt ctcgcttcct ttcttggttt ggtcattgac
    13021 cgttttccag agcaatccat tatcagttca gccagtcact gcgattcctg tcagactcgc
    13081 ttgcgtccct tagatttgat tccgattctc tcacaggtct tcaatcgctt tcgctgtcgc
    13141 tactgcaaag ttcgctatcc tgtctggtat gccctctttg aactaggctt aggactcctc
    13201 tttctgcttt actcttggga attgctttcc ttggggcaag tcgtcctaat caccgctggt
    13261 ttgaccttgg gtatctacga ctttcaccat caggaatatc ccttactggt ctggatgact
    13321 ttccacctaa tcctaatagc ttcctctggc tggaatctgg tcatggtctc cttccttgct
    13381 cttggaattt tggctcattt tatcgatatc cgcatgggcg caggagattt cctcttttta
    13441 gcttcttgtg ctctcgtctt tagcgtaacg gagttactga tcttgattca gtttgcttct
    13501 gcgacgggta tcctggcctt tctcctgaaa aagaaaaagg aaagacttcc tttcgtgcct
    13561 ttcctcttac ttgctacttg tttgattatt tttggtaagc tactgcttgt ctgataaaat
    13621 cctgaatcgg ctctccttgg tggagagctt ttactatttt tgaaccgacg ataacaccat
    13681 ctgacaccgc attgaagcgt tccagatcgg cttgactaga tacaccaaaa cctgtcaaga
    13741 ctgggatgtc ggccacttga tgaagttgcg ccaagtgctt gtccaaatct gcacggtaat
    13801 tgcctgattt ccctgtcact ccattgatgg caacggcata gacgaatccc tccgcccctt
    13861 caatcaactc tttctggcgc tcaattcctg tggtcaagct tactaaagga atcaaggtga
    13921 tatctgtatc tgccaaaaat ggttctacaa agttggcatg ttcatgaggc aagtctggga
    13981 taatcaagcc cttcacagct gtatcagcca gatctttgac aaagttctcc acaccgtact
    14041 gaaagagggg gttgaagtag gtcatgatga ccagtggaat ctctgtttca atggttttca
    14101 aggtttcaac taaagcctgg gtagaggtcc cgtgggctaa actgcgcaag ccagcttctt
    14161 cgataacagg tccatctgca acagggtctg aaaagggaat acccacttca attgcagaga
    14221 cacccaaatc ttctaaaaag tgaattgttt cagcaagacc gtccaaacct ttctcgtggt
    14281 caccagccat gatataggga acaaaaattc cttttccagc tgctttaata gcattcaatt
    14341 tttctgttag tgtcttaggc atgagcttct cccttctttg ctgcatctgc ttccaagcgg
    14401 tctttgactt gaaccacatc cttgtcccca cgacctgata ggcagacaat catagacttt
    14461 tctggtccaa gttctttggc caatttcacc gcaaaggcga tagcatggct agattccaag
    14521 gctgggataa tcccttccac acgagacaag agttggaatc cttccaaggc ttcttcgtct
    14581 gtcacaggga catagctggc acgtttaata tcgtggtagt gagaatgctc tggaccgata
    14641 ccaggatagt ccaaacctgc tgagatagag aaggcttcaa gaatttgacc atgggcatct
    14701 tggagcacat ccatgaggga accgtgaagg acacctggac gacccttggt caaggtagct
    14761 gcgtggtgct ccgtatccac accaagtcca gccgcttcag ctccatacat ggctactgac
    14821 tcatcttcta caaagggatg gaagagaccg atggcattcg acccaccacc aacacaggct
    14881 actagggcat ctggcagatt ttgtcctgtc aagtcacggt actgttgttt agcctctcga
    14941 ccaatgacac tttggaagtc acgaacaatt tctggaaatg gatgaggccc caaggcagaa
    15001 ccaaggatat agtgggtatc atctatatta gccacccatg aacgaagagc tgcattgacc
    15061 gcatccttga gcacgcgcga accatctgtc acggcctcga ccttagctcc caaaagctcc
    15121 atacggaaga cattgagggc ttggcgtttg acatcttcct cacccatgta gatggtacat
    15181 tccatgttaa agagggccgc agcagttgca gttgccacac cgtgctgacc agcaccagtt
    15241 tctgcgataa ttttcttttt acccatgcgt ttggcaagcc aaacttgtcc taaggcattg
    15301 ttaatcttgt gggctcctgt atggttaagg tcttcccgtt tgagataaat cttggctccg
    15361 ccgatatgct gggtcaagtt ttttgcgtag taaaggggag tttcacgtcc cacatactgg
    15421 cgcaaaagtt ggtttaattc ctcttggaaa cttgggtctg cctgactttc acggtaggcc
    15481 ttctccaact ccaaaactgc tgtcatcaat gtttctggga caaaacgtcc gccgaatttt
    15541 ccgtaaaatc catctttatt tggttcttga tatgccattc tttaccctct ctataaatct
    15601 tctaatcttt tcatgatctt tttgtccatc tgtctccact ccgcttgata catctactgc
    15661 atagggagta aagtgttgaa ttgcttttac tacattgtct tcattaagcc cacctgcgat
    15721 aaagaaagac tgaggtaatc cagtcgtatc cagttgaccc caatcaaagg gctggccact
    15781 cccagccaca ggggcatcaa agagtagata gtctgcctga gaattgggca catgaccctc
    15841 tccatctacc tgcacagcct gaatgctagc acaaggcaaa ttctcaaata aatcatctgc
    15901 cacctgaccg tgaacttgaa ccaagtccaa gccaactttg tcaatcgctt ccagcagttc
    15961 tacccgactt ggtgaaacaa atactccaac ctttttcaca tctgcaggaa taagctttgc
    16021 caactcagct gcctcttcta aagtcacctg tcttttacta ggtgcaaaga caaaaccgat
    16081 atagtcggct cctgctgaaa cggctgtttc caccgcttct ttggtcgata gtccacaaat
    16141 tttaaccttt gtcaatctgc aactccttga ttctctgggc cacattttct gcctgcataa
    16201 gagctgtccc taccaaaatt ccgttaaagt atggggctag tcgttccgca tcctgccctg
    16261 tgaaaatggc agattcagaa atgtaatagc gaccttcctc aaagtaaggg gctaaatcta
    16321 cactggtctg caagtcgacc tcaaaggtag tcaagttgcg gttgttgacc ccgataatct
    16381 cagcaccaag tctgtgggct acctctagtt cagctagatt gtgagtctcc actaagactt
    16441 ccagaccaag ctctgtcgcg tagtcataca gttccttgag gcgttcttcg gacaaggctg
    16501 ccacaatgag caagataact gtcgcacctg cattgcgagc gcggatgatt tgcttttcat
    16561 ctatgataaa gtctttgttg agcgtcggaa tctctacctg actggaaatt tcccgtagat
    16621 aatccaaatg ccctttaaag aaaacctcat ctgtcaacac cgaaatcatc actgctccgt
    16681 tttcttcata agtctgggcc tgttgcacaa tatccacatc gagattgata tctcccaaac
    16741 tagggctagc tttcttgacc tcagcgatta cctgcaagcg gtcctgatga ttcttcaaaa
    16801 attctgccaa gcgataggtc tggcgcagag gctggatttg ctccagcttc atctgctcca
    16861 cctcacgcgc cttctgctct aagattcgtg ctaaaaattc ctgactcatt tttggtactc
    16921 ctgtaacagt ctgagttttt caagggcctt gcctctagca atcacttgac gagccaaggc
    16981 aactccttcc ttgatgctat caatcttacc attagcatag aaaccaagac cagcattcaa
    17041 gactgtcgtt tccaagaatg gacttgcttc gtttttcaga acgctaagca aaatttctgc
    17101 attttcctga gcattcccac cacgaatatc ttccatagca tagccttcca ttcccaaatc
    17161 ctctggagta aagcttgaca agctgatttc gccattttca agaagtgcaa tcttggttgt
    17221 tccgttcaag ccagcttcat ccaacccttc tggtccagca accacgatgg cacgtttgcg
    17281 acccatattt ttcaaaacct gagctgtact ttctaggagt tctggacgac taattccaag
    17341 aagctgtgtt tctaaagcca ttggatgaat cagtggacca gtcaagttca taatcgttgg
    17401 aattcccaat tccaaacgag ctggcatgat gtatttcata gctgggtgca tatttttagc
    17461 gaagagaaag acgattccag ttttatcaaa gaccttacct agttcagctg gtttgaggtc
    17521 aagattgatt cccaaggctt cgaggacatc tgcggaacca gatttagaag aaatcgagcg
    17581 gttaccatgc ttggccatgt gaataccgcc accagccaag acaaaggctg cagttgtgga
    17641 aatattaaaa ctgaaagact tgtccccacc tgtaccacag ttgtccatgg catcatgaat
    17701 ctcagttgga atatgctggg catgtcctct catgacttgg gcaatggctg tgcgttcttc
    17761 aggtgtttcc cccttcatct taagagctaa gaggagagaa gcaatctgcg cttcagttac
    17821 acgcccagtt acgatacgct caatgacatc cgtcatttcc acacctgata aattttcaaa
    17881 ttttgctagt ttttcaataa tctctttcat cctagtttcc tcactttaca accttctcga
    17941 taaaattccg aatagaagac aagccgtctg gcgttccaat gctctctgga tggtactgga
    18001 agccataaat cggtaggttt ttatgttgaa tccccatgat ggcttggtca tcagtcgaac
    18061 gagctgtcac ttcaaagtct tctggcattt cctcaatcaa aatactgtga taacgcatga
    18121 ccgcacgtcc ttcctcaata ccttgataca aaacagatgg cgcttcaaag ttgatattgc
    18181 tctgtttccc atgcatgact tttggagcca aacctagctt accaccaaag acttctgcaa
    18241 tggcttggtg gcccaaacaa atcccaagaa tcggcttctt gcctgcaaaa tcacgaatca
    18301 tgtcttccat ctttccagca tcaactggcc aaccaggacc aggagaaaag accagaccat
    18361 ctgctttttc agcttcttca tacagcttgg aatcatcatt tctcagaacc tgaacttctg
    18421 caaaattccc aatgtattgg gccaagttat aggtaaaaga atcatagttg tcaatcaata
    18481 aaatcatggt cttagttctc caattctagt catagatttt gctttgttaa tggtttcttg
    18541 gtattcgttt tgggcgatag agtcgtagac aatccctgcc ccagcctgca cataggctct
    18601 ttgatttttg agaatcatgg ttcggatggc aatggccaaa tccatatcac ccgtcgcaga
    18661 caagtagccg attgctcctg catatacgcc ccgtttttcc gtttccagtt catagatgcg
    18721 tctcatcgcc cgaatctttg gtgctccaga aacggttcca gcaggaagtg tagctttcaa
    18781 ggcatccatg gccgtgagtt ctggaagcaa acgccccttg accacgctgg tcaaatgcat
    18841 gacgtagcgg aagagctcca ccttcatata cttagtaact tggacactgg ccgtttcaga
    18901 gatgcggcca atatcgttac gccccaagtc taccaacatt cgatgttctg ctgtttcctt
    18961 ctcatcagag aggaggtcag tcgccaaggt cttgtcttct tcatccgtag cccctcttgg
    19021 tcgcgtccct gcaatcggat tggttgtcac gatgccattt ttgacagaaa ctaaactttc
    19081 tggactagct ccgatgattt gataatcccc aaaatcatag aaataaaggt aattagaagg
    19141 attagtcacg cggagatttc tgtagaagtc aaatggattt ccagtaactt ctgctgaaaa
    19201 acgctggctg agtacacatt ggaacatatc tccgttacga atcaagtcac gagctgtttc
    19261 taccattccc tcaaacttat gtggagcgat atgcggtttg aagtctaacg gagatagatc
    19321 caaatcttca aattcatttg gagcaggaat gcgtaattcc tcaagcactt ggttcaagga
    19381 tttttccaag gcctcttgac tgcgctcact ataaagtgca tcctctatga catgtatctt
    19441 ctccttcttg tggtcaaaga ccatatagct ctcatagaca aagaaatgca tgtctggcgt
    19501 cccaattgta tcctcaggga tttgaccaat ttcttcataa agcgaaatca tatcgtaacc
    19561 cacaaaacca atggctccac caccaaaagg tagctctgag tggtgctgac tcttatgaat
    19621 cacttcataa aggaaatcca agggatcccg atcaatcact tgaccatttt gatagagaac
    19681 cccattttca aacttaatct caaaaactgg attataggct aggatagaaa aacgagctgt
    19741 ttccttgtct ctcggaatac tctctaaaat aaccttatgt tgccccttta agcgcatata
    19801 agccaagatt ggtgataaga catctccatg aatgattcgt tccattgtaa tttccctttc
    19861 agttctactt ctagtccgtg gtgactgtat gaaaaatccc cacgcaaaat aacttgcgtg
    19921 aggacgaaat tcgcggtgcc acctcaatta taggatttct cctatctctc attcctgtct
    19981 cagatatctc ctgtaacagg ctgtgcgata aagggcactc ccttgagaat gatgttttct
    20041 tctctcgttt cagatgaacc caactttaca gctttctctg cttgttttca gcaaccacaa
    20101 gctctctgtg agagaaagaa ctgtaatttt tccatctatt attttttagc ttctagtaat
    20161 ctgcaatcgc agctaggtcc ttgcctccac gaccagagac attgatgaag agatgttcat
    20221 ctcggtacac ctttatactc ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg
    20281 taggtatggt t
//
LOCUS       DAVKXA010000038        18906 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKXA010000038 DAVKXA010000000
VERSION     DAVKXA010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.038"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            137..397
                     /locus_tag="VW883_001499"
     CDS             137..397
                     /locus_tag="VW883_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274618.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(1162..1561)
                     /locus_tag="VW883_001500"
                     /pseudo
     CDS             complement(1162..1561)
                     /locus_tag="VW883_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1686..2144
                     /locus_tag="VW883_001501"
     CDS             1686..2144
                     /locus_tag="VW883_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0274619.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            2157..2765
                     /locus_tag="VW883_001502"
     CDS             2157..2765
                     /locus_tag="VW883_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274620.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            2836..3168
                     /locus_tag="VW883_001503"
     CDS             2836..3168
                     /locus_tag="VW883_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274621.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPISYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            3179..4594
                     /gene="ply"
                     /locus_tag="VW883_001504"
     CDS             3179..4594
                     /gene="ply"
                     /locus_tag="VW883_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0274622.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            5475..6191
                     /locus_tag="VW883_001505"
     CDS             5475..6191
                     /locus_tag="VW883_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0274623.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            6315..6785
                     /locus_tag="VW883_001506"
     CDS             6315..6785
                     /locus_tag="VW883_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0274624.1"
                     /translation="MDKPMLVFKRFGHQIYLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            6801..7622
                     /locus_tag="VW883_001507"
     CDS             6801..7622
                     /locus_tag="VW883_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274625.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVAVIINVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLGVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            7629..8660
                     /locus_tag="VW883_001508"
     CDS             7629..8660
                     /locus_tag="VW883_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0274626.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVRQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            8726..9088
                     /locus_tag="VW883_001509"
     CDS             8726..9088
                     /locus_tag="VW883_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEV0274627.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDSLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            9085..9588
                     /locus_tag="VW883_001510"
     CDS             9085..9588
                     /locus_tag="VW883_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0274628.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSAAIISMACLHASLPIGLVCLNFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLL"
     gene            9702..10148
                     /locus_tag="VW883_001511"
     CDS             9702..10148
                     /locus_tag="VW883_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274629.1"
                     /translation="MKLRIEIDGNLEETEIVIKAAALTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            10153..10827
                     /locus_tag="VW883_001512"
     CDS             10153..10827
                     /locus_tag="VW883_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274630.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            10988..11179
                     /locus_tag="VW883_001513"
     CDS             10988..11179
                     /locus_tag="VW883_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0274631.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            11516..11815
                     /locus_tag="VW883_001514"
     CDS             11516..11815
                     /locus_tag="VW883_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0274632.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            11812..12129
                     /locus_tag="VW883_001515"
     CDS             11812..12129
                     /locus_tag="VW883_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0274633.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            12145..12771
                     /locus_tag="VW883_001516"
     CDS             12145..12771
                     /locus_tag="VW883_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0274634.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            12804..13565
                     /locus_tag="VW883_001517"
     CDS             12804..13565
                     /locus_tag="VW883_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0274635.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            13643..14038
                     /locus_tag="VW883_001518"
     CDS             13643..14038
                     /locus_tag="VW883_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0274636.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            14194..14478
                     /gene="groES"
                     /locus_tag="VW883_001519"
     CDS             14194..14478
                     /gene="groES"
                     /locus_tag="VW883_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0274637.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            14494..16116
                     /gene="groL"
                     /locus_tag="VW883_001520"
     CDS             14494..16116
                     /gene="groL"
                     /locus_tag="VW883_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0274638.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            16254..17009
                     /locus_tag="VW883_001521"
                     /pseudo
     CDS             16254..17009
                     /locus_tag="VW883_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            17455..18228
                     /locus_tag="VW883_001522"
     CDS             17455..18228
                     /locus_tag="VW883_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0274639.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            18241..18579
                     /locus_tag="VW883_001523"
     CDS             18241..18579
                     /locus_tag="VW883_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0274640.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            18612..18906
                     /locus_tag="VW883_001524"
                     /pseudo
     CDS             18612..18906
                     /locus_tag="VW883_001524"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT         5776 a         3286 c         4214 g         5630 t
ORIGIN      
        1 aaaatctctt caaaccacgt cagcttccat ctacaacctc aaaacagtgt tttgagcagc
       61 ctgcggctag cttcctagtt tgctctttga ttttcattga gtattaatta tttttaaggc
      121 taaagcttgg ctggatatga gggaacgctc tgctacaggt gctcaaggtt taagtaagtc
      181 cattaaaaag catttgaatg accttacccg tttgacagct tccttgctag gagatgaaaa
      241 gttatcggct ataacatcaa gtagtgcggt aaaagcagac atgcaccgct ttgtgataga
      301 attagagcct gtgaagtcaa ctattcttca aaatgatgac atttcattag atcaaaatga
      361 aatttttgaa attctgaaaa attttttcga tggttaaaat aattgtagcg agatggctat
      421 attgaattcg tttatatctg gaaactagaa aaaacttcaa tttcaggaga aaatgaagtc
      481 aatcttccca caatcaaacg tatagtatca aggtttttca agacctgata ttatgcgttt
      541 tttgcttttc aaaacttttt gcccagtttt tgtttttatc ctctagtcac ttgatttgtt
      601 tcaggtggtt ttttagtata gtaaaatgaa acgagaacag gacaaattga tcaggacagt
      661 caaatcgatt tctaatcaat gttttagaag cagaagtgta ctattctagt ttcaatctac
      721 tatagttaaa tctgcggtca agtctactgg tggatctatg attgtaatac tcttccaaaa
      781 tctcatcaac cacgtcagtc ttgccttgca gtctgtatct tactgaccaa gctagtgatg
      841 gacttagaat aggtgatttg gagcgtccta ttggctagga aatgctgatc atagtccttt
      901 gctgaggcta gggtgtttca acattcaaca ctcaactggt tgatctagtt gataggaagg
      961 gaattactat aaaatactca ggcttccatc atattttttg aaacgattgt gtaatcaaaa
     1021 tgtaccaata ttgtagtatt ggtacagaag atgttgtgaa tggataaata tatcataact
     1081 gctgtctctc tatgtaaaaa gaaggttgta tcaaaaagat ttcatatgtc tgtgcatata
     1141 tataatagac tttctgcaag actagaatcc tagttcatga tttataatgc cagcaatcaa
     1201 attcattcgt aatccaaagc gtttacgatg atttcgatag gttgttgaaa acattttaaa
     1261 cgtttctact ttggcaaaga tgttctcaac cttgcttctc tccttagata gcgcatggtt
     1321 ataggtttta tcttcaactg ttagcggctt gagtttgctg gatttacgtg gaatttgtgc
     1381 ttgaggatat atcttcatga gcccttgata accactgtca gccaagattt taccagcttg
     1441 tccgactttt ttgataagct gtttttaata cagctaatat ctcttcaaaa gtggtacgct
     1501 gaacactaac aagacgctta aatcgtgcat cagttagttg tttacttgct tcataattca
     1561 tagaactact ataccatatt ttgtttcgca ggaagtctaa taagttatag tccagttttt
     1621 actatacttt gatattcaaa tatgttatac tatggttatc aaagtaaatg aaaggagtta
     1681 cgaatatgac gccagaagaa atgtacctga cagagcgatt agacgtacag atagctcatt
     1741 ttttaaagaa aagcgttcaa catcgtaggc gctataaggt attaaaaata acagaaatcg
     1801 tggcaggttt cctcatagct gtcttttgtg ctattcctat gccaggtgat cgctaccgtt
     1861 tgatttcggt tgccttatcc agtctcggct tgctgtgtga ggggattatc aatttgtata
     1921 atgcaaagga aaattggatt tcttaccaaa aaactgcgca actcctggag aaagaaaaat
     1981 tcctctatca atgccaaacg gagaaatatg caggaaagac caaggctttt gccctatttg
     2041 tcaagacatg cgaaggtctt atctcagagg agattaacca gtgggaaagt atccagtcaa
     2101 aagaagtggc agctagtgca gatgctccag ttaaaaaaga gtaggaggta gaggaaatgt
     2161 ctcaatccag ttacctgtcg cccttgctct ggttaaaaaa agaagccgat aaggaaaaga
     2221 tgagcgcgac ccagtgccag atatttttct tttactatca aatgtttgag ctcttatttg
     2281 ctagagaaag cgacatgaaa gacttatgtc tgggaacgaa aggtttttat ttctcgcagt
     2341 tagagaaaaa tttgctttct ggagtttccc gatttctaaa aaacttggag gggaaagtaa
     2401 ctctcaaggc taaccaagaa gtatcagctc gcaaagccct ttttctagcc ttgacaacta
     2461 gccaatcaga ttggcaggag ttagctcctg tttttgattt ttatcagact atcgggaggc
     2521 ttgaaaatcc ttctctcttg agttctcagg acagacaaca tctgatgtgg atttaccagt
     2581 cagctttgga gaaggattat attgtcaagg ttattggcga caagcatttt gtattgaaga
     2641 gacaagatgc tactaaattg acagcgcgcc aaactcaaac tttggaaatt ctgagtcaat
     2701 cagaagactt ggtcaatcct gtctatgtta cattaggaga aaagggggtg ctcttgcttg
     2761 attaagagag gagatgttgt agctctttat ttgccttttc cgactattag tagcgatttg
     2821 gctgtgaaga atcatatgta tatctgtatt gacaacagca tgactaaaaa caaagagttg
     2881 gttaaaaatc agaccttcaa accagctctc ttgaccagac gtttggtcaa gaactttatg
     2941 atagaagagc cggatctagc tcgtaatcct tttacaagac caaccttgat tgacttagat
     3001 aaggtattta tgttggataa tacggttatt ccgatttctt atctagccag acggcgacgc
     3061 aatgtctcag aagaattgta cgaggaaatt ttggatcact tagtccaacc acggctgatt
     3121 tcgctgaaca agtctgagtt tatgcaactc aatccaggaa cttattagga ggtagaagat
     3181 ggcaaataaa gcagtaaatg actttatact agctatgaat tacgataaaa agaaactctt
     3241 gacccatcag ggagaaagta ttgaaaatcg tttcatcaaa gagggtaatc agctacccga
     3301 tgagtttgtt gttatcgaaa gaaagaagcg gagcttgtcg acaaatacaa gtgatatttc
     3361 tgtaacagct accaacgaca gtcgcctcta tcctggagca cttctcgtag tggatgagac
     3421 cttgttagag aataatccca ctcttcttgc ggtcgatcgt gctccgatga cttatagtat
     3481 tgatttgcct ggtttggcaa gtagcgatag ctttctccaa gtggaagacc ccagcaattc
     3541 aagtgttcgc ggagcggtaa acgatttgtt ggctaagtgg catcaagatt atggtcaggt
     3601 caataatgtc ccagctagaa tgcagtatga aaaaatcacg gctcacagca tggaacaact
     3661 caaggtcaag tttggttctg actttgaaaa gacagggaat tctcttgata ttgattttaa
     3721 ctctgtccat tcaggcgaaa agcagattca gattgttaat tttaagcaga tttattatac
     3781 agtcagcgta gatgctgtta aaaatccagg agatgtgttt caagatactg taacggtaga
     3841 ggatttaaaa cagagaggaa tttctgcaga gcgtcctttg gtctatattt cgagtgttgc
     3901 ttatgggcgc caagtctatc tcaagttgga aaccacgagt aagagtgatg aagtagaggc
     3961 tgcttttgaa gctttgataa aaggagtcaa ggtagctcct cagacagagt ggaagcagat
     4021 tttggacaat acagaagtga aggcggttat tttagggggc gacccaagtt cgggtgcccg
     4081 agttgtaaca ggcaaggtgg atatggtaga ggacttgatt caagaaggca gtcgctttac
     4141 agcagatcat ccaggcttgc cgatttccta tacaacttct tttttacgtg acaatgtagt
     4201 tgcgaccttt caaaatagta cagactatgt tgagactaag gttacagctt acagaaacgg
     4261 agatttactg ctggatcata gtggtgccta tgttgcccaa tattatatta cttgggatga
     4321 attatcctat gatcatcaag gtaaggaagt cttgactcct aaggcttggg acagaaatgg
     4381 gcaggatttg acggctcact ttaccactag tattccttta aaagggaatg ttcgtaatct
     4441 ctctgtcaaa attagagagt gtaccgggct tgcctgggaa tggtggcgta cggtttatga
     4501 aaaaaccgat ttgccactag tgcgtaagcg gacgatttct atttggggaa caactctcta
     4561 tcctcaggta gaagataagg tagaaaatga ctaggagagg agaatgcttg cgacaaaaag
     4621 aggcgatgat ctctctgcgg atatctgaaa gtttatctct tgcctagcga tttccattgg
     4681 agtatgctcg tgatgttaaa atgaatctat caaacagaat gtgtaaaaaa gtaaaaaggg
     4741 tagccaattc cttgatatac aggggattga ttatccttta cttgttttag atgattggaa
     4801 attcaagaat gacacgtatc ggaaatattt tgctgtttat atctaatacc catttatgga
     4861 aaaaatgaaa ttaaatatga acaaatcaat tgctagcaat ggtttagaag tgccagtgta
     4921 ctagtctaat ttctccatct tgggaacacg taaattatac tcttcgaaaa tctcttcaaa
     4981 ccaggtcagc cctatccgca acctcaaaac agtgttttga gcaacctgcg gctagctttc
     5041 tagtttgctt tttgattttt attgagtatt agaggtttgc ttagaaactc ttctattgat
     5101 ttcttggaat acaatagcgc ctataagaac tgttggattt caaagtattt acttgaacta
     5161 tgatatgtct ggagtagact gtcaacaaaa ggtgcagtat gattgttttt gtcgcttata
     5221 tctacaaact tcaaacagta atttgagctg actttgtcaa acttggctga aactttctat
     5281 ttgcagataa tggtctagtt tgttttttga atgtggatga gtgtctgttg ataaagatag
     5341 aaaggtaaga ccatcttagc aggtaaagtg ctatcctagc ttgatttgct aataaaatcc
     5401 atttcctcta gtgaaaatca aaaaaacttg tgttataata agaaagatta aaatgtgaaa
     5461 aaaggagatt cctaatggga cgtaaatggg ccaatatcgt agccaagaaa acggctaaag
     5521 atggagctaa ctctaaagta tatgcaaaat ttggtgtaga aatctatgta gcagctaaaa
     5581 aaggtgatcc agatccagaa tcaaactcag ctttgaaatt cgttatcgac cgtgctaaac
     5641 aagcccaagt gccaaaacac attatcgata aagcgattga taaagccaaa ggaaacacag
     5701 acgaaacctt tacagaagga cgttacgaag gttttgggcc aaatggctct atgctaattg
     5761 tggatacttt gacttctaac gttaaccgta cagcagccaa tgtccgtgca gcctttggta
     5821 aaaacggcgg aaacatgggc gcttcaggtt ctgtttctta cctttttgac aacaaaggtg
     5881 ttattgtatt tggaggtgaa gatgcggacg cagtctttga gcaattgctc gaagcggatg
     5941 tggatgtgga tgacgtagaa gcacaagaag gtacaatcac agtttacaca gcgccaactg
     6001 accttcacaa ggctatcgtt gctctccgtg agtctggtat tgaagaattc caagtgactg
     6061 aattggaaat gattcctcag tcagaagtgg aattgtcagg cgaagacctt gaaacctttg
     6121 aaaaacttta cagcgttctt gaagacgacg aagacgtcca aaagatttat acgaacgtag
     6181 atgggtttta atttaaccta tagaacatga tcctaagtga gaaaatcact tgggattttt
     6241 ttaatcaaga aaatagttct catagaaatt taattattct ccagagaact atttttattt
     6301 agaaggggga gattatggat aaaccgatgt tagtctttaa gcgttttggt catcaaattt
     6361 acctgatggt gcaaaaggaa gccaaacgtt gcggcattga atttatgggt gggccgcaag
     6421 gtcaggttgt gcgttttttg gataatcgcg agaaaaacca agacttggtc ttgattaaag
     6481 atatcgagca ggaactcaat attaccaagt ctgttgctag taatctggtt aagcgtatag
     6541 tgcaaaatgg tttggtggaa ttggaggcga gtcctgttga taagcgggct aagtttgttc
     6601 gtctgacgga caaagcacgt tctcagatgc aacaggttaa ggcttttttt gaacgcatag
     6661 acaagcagtt gatggaagac attgatgaag atgaattact gatttttgag aaagttctcg
     6721 gtcaactaca ggcaaatatc aagggaatag gaggagagaa taaagaaatt agccaaaaga
     6781 attagtagaa aagaatgggg gtgattttac tagccattct ctttacttgc ttttcggtct
     6841 atctagagtt ggaagtgccg acctatatct cgaaaattac ggatttgcta ggtagtcaag
     6901 aaactaattt agatgagttg tggcagccgg caagcatgat gatgggaatg tcctttcttg
     6961 ccttcttgtc cgtagttgca gttggatttt ttgcatcccg agtggcggct tcttatacta
     7021 gtaggctgag aagtgatatt tttaaccgag ttttggatta ctcgcagaca gagattaaga
     7081 aattttcaat tcctagcctc ttgacgcgta ctaccaatga cattactcaa gttcaaatgt
     7141 tgattactat gggcttgcaa gtggtaacgc gtggttcaat tatggctatc tgggctattg
     7201 ggaagatttt aggtcattca gaatactggc tctgggccgt acttgtggca gtgattatca
     7261 acgtcctgat gacgaccgtt ttgatgacgc tagcctttcc aaaacagtcc ttgattcagg
     7321 ggctgacaga taaactgaac agtatcactc gtgagagttt aacaggtatt cgtgtcgttc
     7381 gtgcctacaa tgcagaggat tatcaaaatg aaaaatttgc agcagtaaat gatgaattga
     7441 cccgtttgaa tttgtttgtc aaccgtctta tggctatttt gaatcctatc atgatgggga
     7501 tttcaagtgg tttgggtgta gcgatttact ggattggggc ctatgtgatt aacgacgctg
     7561 ctccgatagc gcgtctgcct ctctttagtg acatgattgt tttcatgtct tatgccatgt
     7621 aggttgtcat gggcttcctt ctcatgggag cactcttcat cgttcttccc cgaactatgg
     7681 tctctgctaa gcggattaat caagttttag atttgcattc ttctatccaa aaccctgttc
     7741 aagtgcagct gactgatgaa aacttcaaag gtcaggtcga gtttaaggat gtgaccttcc
     7801 gctatgcggc aaattcggag gcagttattg aacatgttag ctttaaagca gaaactggtc
     7861 aaacagtggc ctttattggg tcaacaggtt ctggtaaatc aactctggtc aatctgattc
     7921 cacgtttcta cgacgtgtca gcaggagaaa ttctggtgga cggtgtcaat gttcaagact
     7981 atgacttctc tgcgacagct catgctggtc aaaaggttgc cattgttggg ccgactgggg
     8041 ctggtaagac aaccattgtc aatcttttga tgaaattcta tgagattgat aagggaagta
     8101 ttcgcattga tggtgtggat accaaggcta tgacgcgttc agaagtgcat gatgcctttt
     8161 caatggtctt gcaggatacc tggctctttg aaggaactat tcgagacaat ctcatctata
     8221 atcaaatagg gattagtgat gaacgaatga tggaagctag taaggctgtg ggaattcacc
     8281 actttattat gaccttgcca gatggctatg ataccatctt ggatgacacc gtgaccttgt
     8341 ctgtaagaca aaaacaacta ttgactattg ctcgtgccct tcttaaggat gcaccgcttt
     8401 tgattttgga tgaggcgact tcttctgttg acacacggac agaggaattg atccaaaaag
     8461 ccatggaccg tttgatggaa ggacgcacat cctttgtcat tgcccaccgc ttgtcaacca
     8521 tccgaaatgc agacttgatc ttggtcatga aagatggaaa tatcatcgag caaggcaact
     8581 atgaggaact gatggcgcaa ggtggcttct acgctgactt gtacaatagt caatttacag
     8641 aagatgaagc agaagaataa atcaaaagaa ggcttgacga ccttcttttt cttatttata
     8701 ctagtacaca tagaaagaga gaagtatgag tcagaaatta tacaatatga aatttgctgc
     8761 tgtctactta gccttgattg caaaagttga gcgaaagggt ggaaaggcag agtcagttca
     8821 ccaagtgacc agttggttga cagggtatga agtgagtgac gttcttgctt gtctggatag
     8881 ggatgttact tacggagatt tttttcgaca agcaccatat tatgtccctg aacgaattgc
     8941 aattacaggg aagatttgcg gtgtccgtat tgaggaaatt gatgattctc tgatgcagga
     9001 aatacgtcgc ttggacaagc tagtggattg gcttgccaag gggaaaacat cccaacaagt
     9061 tctagaaaag tatgagaagc ataaatgaaa aattatcaag aatggtatcg aaatatcagc
     9121 tccagactaa ctagtcgtcc aattctttta ttcctattac gcagtttcaa tcgtttgatg
     9181 acagtcgcca tgcccctggt ctatctgatc ttgctagtca ccacttacct gcaactagga
     9241 cttggtcagc aagttggggt ttatgtgctt attcctgcat caggttttgt gaccttgtcc
     9301 ctgtttcgta agaaaatcaa tcacccgaga ccttatgaaa cttgggatat ctgtcccctt
     9361 cttgataagg atagttcggg acggtcgatg cccagtcgcc atgtcttttc ggcagctatc
     9421 atctccatgg cctgtctgca tgctagtcta cctattggct tagtatgctt gaacttttca
     9481 gctttgctgg ggttggtgag ggttttaggg ggtgttcatt atcccaagga tgtcttggtt
     9541 ggctatgctt gtggtctggt gtggggattc cttttcttct tattatgaca tgtaagttaa
     9601 gctagtccta caaccactta ctgcttcaaa ttgaccactt gcttttttgc ccttgtattc
     9661 ctaacttagc tttgatatag tagagtcaga aaggagatgt gatgaagtta cgaattgaga
     9721 ttgacggcaa tttagaggag actgaaattg tcatcaaggc agcggctttg acagatgaga
     9781 ttgcggattt acagcggctc ttgcaagaat ccaagtctcc taggttgatt ttttataagg
     9841 ggacgggtga atattatctg gacttgtcgg aaattctctt ctttgagaca gaaggtagca
     9901 agatttatgc ccatacccag aaaaatgcct acgaagttcg gctcaaactc tatgagttag
     9961 aggctatcct tcctcgctat tttagtcgag tatccaagtc aacgatcgct aatattcggc
    10021 aaatctattc ggtggacaag tccttttcag gaacgggcac catttccttt tatcaaaccc
    10081 acaaggaggt tcatgtgtca cggcattacc aatccctcct aaaagaaaat ctaagaaata
    10141 tgaggtaaga acatgaaaaa gaaagcattt ggtattgttt tattggtttt agcagcttgg
    10201 atcttgctgc aagggaattt tggaattcct tctctaggag ggcacatttg gcccttgatt
    10261 ggtattgctt tttttgccta ccaatcagtt ggagctttgt tgcgtcgcca cttaacttca
    10321 gcctctttta cagctctagt agccttaatg attgctaacc acttttatgg cattttaccg
    10381 attccaaacc agacactaat ctgggcagga gttctaatcg ttctcggagt aaatatgttg
    10441 actcattcta acagaacttg gaatgggaaa aaatggtggt acaatgggaa aaaaacagtc
    10501 gtcacggata aggaagtcgc ttttggtagc gggaccttct ataagcaaga tcaagatctc
    10561 gtagatgacc aagtggaagt cgcttttggg gatgctaaaa tctactatga taatgcagag
    10621 atgctaggtg attttgcaac tttaaatatt gaagtggcct tcggaaatgc aaccgtctat
    10681 gttccacaac actggcgtgt agatttgaaa gtagaaacct cctttggtgc agctaaggct
    10741 gacgctcctg tagccccaac cagcaaaacc ttgactatcc gtggagatgt ggcttttggg
    10801 aagttggaaa ttgtctacgt taaataaaaa aatcttcact tcaaccatca aaatagacgt
    10861 actaagagta ggaaattgat gccttgctct gatttcagtt ctatggttgt tagactttaa
    10921 aaaatgaaat gctgccttta aaagttgtat atttttcgat attttggctt ttacgtttga
    10981 tgtatctatg tactacagcg tagatgatgt agtgtcaaat gcttttaaaa aacgaatgat
    11041 attggacagt ttttttgcct ttaattgctc aggaaccatg aaagtcagta cttgggttta
    11101 tgacaaggga gaatggtatt atgtaagttc ttctggttcc atgattgcga atgattgggt
    11161 caaagacaat ggcaagtagt attatctggc ttcatcaggt aagatgcttc gcaataccta
    11221 cacacctgat ggttactacg ttggcaactt aggtgcctgg caataagaat aatactcttt
    11281 gaaaatctct tcaaaccacg ccagcttcat ccacaacctc aaaacagtgt tttgagctga
    11341 cttcgtcagt tctatctaca acctcaaagc agtgctttga gcagcctgcg gctagcttcc
    11401 tagtttggtc tttgattttc attgagtata agaagtcctt ttccttaaag gaagaggctt
    11461 tttacttgct tttctgctgc ttcctcattt gtcctgaagc cttttttgtg ttaaaatgaa
    11521 tggtatgaaa gctaaaaaaa tgtggatggc aggcttggct ctgctaggta tcggaagcct
    11581 tgctcttgcc acgaaaaaag ttgcagatga ccgtaagctc atgaagactc aggaagagtt
    11641 gacagagatt gtgcgagacc atttttccga catgggggaa attgcgaccc tctatgttca
    11701 agtttacgaa agcagtctgg agagcttggt tggtggcgtc atttttgagg atggtcgtca
    11761 ttataccttt gtctatgaaa atgaagacct agtctatgag gaggaagtct tatgatacag
    11821 ccagcaagtt tagaagaatt agcatcttta gtggaaaaag cgggcaagaa ggtcttcctt
    11881 tttgtggcag actggtgtgg cgattgtcgt tatatttatc ctgccttacc agagattgag
    11941 gagaccaatc cagagttcac ctttattcga atggaccgag atcagtatat ggatttggcc
    12001 aaactctggg atgtttacgg aattcctagc cttgttgttc tagaaaagga caaggaaatc
    12061 ggtcgttttg tcaatcgcga ccgtaaaagt aaggagcaaa ttaacgattt tttagcagga
    12121 ttgaaatagg agaaaaagga aacaatgatt tttacgtata acaaagaaca tgtcggtgat
    12181 gtccttatgg tcatcgtgaa aaatagcgga gatgccaaac tgaatgtgga acgcaaaggc
    12241 aaggtagccc gtgttttcct caaagaaaat ggggaaacag tagcttggaa catttttgag
    12301 gtttcgagct tgtttgaaat tgcagagcgc ggtcaagtct ttttatcaga tgagcaagtc
    12361 gctcgtttga accaagaatt acaggcggaa ggttttacag aagaaattgt taatgataag
    12421 gaacctaagt ttgttgttgg tgaaattgtc gagatggtag ctcatccaga cagtgaccac
    12481 ctcaacatct gccaagttgc agtcgcaagt gacaagatag tgcaaatcgt tgcaggagca
    12541 cctaatgcgc gtgttgggtt gaaaaccatt gtggctcttc ctggtgccat gatgccaaaa
    12601 gggaatttca ttttcccagg cgaacttcgt ggtgaaaaga gttttgggat gatgtgtagt
    12661 cctcgtgaat tgcatttgcc aaatgctccg caaaaacgtg gggtgcttga attatcagaa
    12721 gaccaagttg tcggaacacc gttcgaccca gcgaaacact ggactgccta ggaacttgtc
    12781 agcatctgat agaaggaaat aagatggcaa aaaatgtagt gattacggga gcaacctcag
    12841 gaatcggtga agcgattgcg cgtgcttatc tggagcaggg tgaggatgtc gttctaacag
    12901 gacgacggat agacagacta gaagctctta aggcggagtt tgcagaaact tttccaaatc
    12961 aaacagtttg gacttttctc ctagatgtca cggatatgac aatggtaaag actgtctgct
    13021 ctgatatttt agaaacgata ggtcagattg acatcctggt caataacgca ggactggctc
    13081 ttggcttagc tccctatcaa gactatgaag agttggatat gctgaccatg ttggatacca
    13141 atgtcaaagg tttgatggca gtcactcgct gtttcttgcc agcaatggta aaagccaatc
    13201 aaggtcatat tatcaatatg gggtcaaccg caggaattta tgcctatgct ggtgcagctg
    13261 tttactcagc caccaaggcg gcagttaaga ccttttcaga tggactgcga attgatacca
    13321 tcgcaacgga tatcaaggtg acgaccattc agcctggaat tgtcgaaaca gatttttcta
    13381 cagtgcgttt tcatggtgat aaagaacgag ctgcgtccgt ttaccaagga atagaagcct
    13441 tgcaagctca ggatattgca gacacagtag tctatgtgac cagtcagcct cgccgtgttc
    13501 agattacaga tatgaccatt atggccaatc aacaggcgac aggtttcatg gttcataaaa
    13561 aataaaaaat tttctcgaaa agttacaaat ttctgtaact ttttttgatt tcctacgaat
    13621 agataagtag gaggaagaaa atatgtataa taaagttatc atgattggac gtttaacgtc
    13681 tacaccagaa ttgcacaaaa ccaacaatga caagtcagta gcgcgagcaa ctatcgctgt
    13741 caaccgtcgt tacaaagacc aaaacggtga acgtgaagct gattttgtca atatggttct
    13801 atggggcaga ctagcagaaa ctttggcaag ctacgcaacc aaaggtagtc tcatttccgt
    13861 tgatggagaa ttgcgtaccc gtcgctttga gaaaaatggt cagatgaatt atgtaaccga
    13921 agtccttgtg acaggattcc aactcttgga aagtcgtgcc caacgtgcta tgcgtgaaaa
    13981 taatgcaggc caagatttgg cagatttggt cttggaagag gaagaattgc cattttaaga
    14041 attaaaaagt ctgagttggt ctcaggcttt ttatcttgag aaagtcagac ttttttcttg
    14101 attatttctg actaagtgat acaatagaac tatgaattag cactcaggta taaagagtgc
    14161 taataatatc tatctcatta tggaggaaat cagatgttga aaccattagg ggaccgtgtg
    14221 gtcttaaaag tagaagaaaa agaacaaact gttggaggct ttgttctcgc aggttcagcc
    14281 caagaaaaaa ccaaaacagc ccaagttgtg gctactggac aaggtgttcg taccttgaac
    14341 ggtgacttgg ttgctccaag tgttaaaact ggagatcgtg tcttagttga agcccacgca
    14401 ggtcttgatg tcaaagatgg cgatgaaaag tacatcatcg taggcgaagc taacattttg
    14461 gcaatcattg aggaatagaa ggagaaagta agtatgtcaa aagaaattaa attttcatca
    14521 gatgcccgtt cagccatggt tcgtggtgtc gatatccttg cagacactgt taaagtaacc
    14581 ttgggaccaa aaggtcgcaa tgtcgttctt gaaaagtcat tcggttcacc cttgattacc
    14641 aatgacggtg tgaccattgc caaagaaatc gaattggaag accattttga aaatatgggt
    14701 gctaagttag tatcagaagt agcttctaaa accaatgata tcgcaggtga cggaactacg
    14761 actgcaacag tcttgaccca agctatcgtc cgtgaaggaa tcaaaaacgt cacagcaggt
    14821 gcaaatccaa tcggtattcg tcgtgggatt gaaacagcag ttgccgcagc agttgaagct
    14881 ttgaaaaaca acgccatccc tgttgccaat aaagaagcta tcgctcaagt tgcagccgta
    14941 tcttctcgtt ctgaaaaagt tggtgagtac atctctgaag caatggaaaa agttggcaaa
    15001 gacggtgtca tcaccatcga agagtcacgt ggtatggaaa cagagcttga agtcgtagaa
    15061 ggaatgcagt ttgaccgtgg ttacctttca cagtacatgg tgactgatag cgaaaaaatg
    15121 gtggctgacc ttgaaaatcc gtacattttg attacagaca agaaaatttc caatatccaa
    15181 gaaatcttgc cacttttgga aagcattctc caaagcaatc gtccactctt gattattgcg
    15241 gatgatgtgg atggcgaggc tcttccaact cttgttttga acaagattcg tggaaccttc
    15301 aacgtagtag cagtcaaggc acctggtttt ggtgaccgtc gcaaagccat gcttgaagat
    15361 atcgccatct taacaggcgg aacagttatc acagaagacc ttggtcttga gttgaaagat
    15421 gcgacaattg aagctcttgg tcaagcagcg agagtgaccg tggacaaaga tagcacggtt
    15481 attgtagaag gtgcaggaaa tcctgaagcg atttctcacc gtgttgcggt tatcaagtct
    15541 caaatcgaaa ctacaacttc tgaatttgac cgtgaaaaat tgcaagaacg cttggccaaa
    15601 ttgtcaggtg gtgtagcggt tattaaggtc ggagccgcaa ctgaaactga gttgaaagaa
    15661 atgaaactcc gcattgaaga tgccctcaac gctactcgtg cagctgttga agaaggtatc
    15721 gttgcaggtg gtggaacagc tcttgccaat gtgattccag ctgttgctac cttggaattg
    15781 acaggagatg aagcaacagg acgtaatatt gttctccgtg ctttggaaga acccgttcgt
    15841 caaattgctc acaatgcagg atttgaagga tctatcgtta tcgatcgttt gaaaaatgct
    15901 gagcttggta taggattcaa cgcagcaact ggcgagtggg ttaacatgat tgatcaaggt
    15961 atcattgatc cagttaaagt gagtcgttca gccctacaaa atgcagcatc tgtagccagc
    16021 ttgattttga caacagaagc agtcgtagcc aataaaccag aaccagtagc cccagctcca
    16081 gcaatggatc caagtatgat gggcgggatg atgtaagctt tctatagaaa acaacttata
    16141 aaaaacacaa aaggagggaa tgactaaccc ttctttttat aatattcact tctaaattga
    16201 tttgagctct cctaacttat atgataaaat aagactagaa aaaggagaag aacatgatcg
    16261 atgtagaaga aattctgtgc aagatgaccc ccaatcagaa gattaattat gaccgtgtca
    16321 tgcagaaaat ggtacaagca tgggaaaaaa atgagtagcg gccaaccatt ctcgtgcatg
    16381 tttgctgtgc cccttgtagt acctatacac tagaatattt gaccaagtat gcagatgtga
    16441 ccatctattt tgccaattct aatatccatc ccaaggcaga ataccataag cgggtctatg
    16501 tcaccaagaa atttgttagt gattttaatg agcggacagg aaatacggtt cagtacctag
    16561 aagctcccta cgaacccaat taataccgaa aactagttag ggggctagag gaggagcccg
    16621 aaggtggcga ccgttgcaag gtttgttttg actaccgact ggataaaaca gcgcaagtgg
    16681 ctatggactt gggctttgac tactttggtt cagccttgac catcagtcct cataagaatt
    16741 ctcaaactat caatagcatc ggaatcgatg tgcaaaaaat ttacacgccc cactatcttc
    16801 ccaacgattt caagaaaaat caaggctaca aacgttcagt agagatgtgt gaggagtatg
    16861 atatctatcg tcaatgttat tgtggctgcg tctatgcagc ccaagcccag aatattgacc
    16921 tggtttaagt taagaaggac gccacagcat gcttgttgga taaggatgtt gagaaagact
    16981 attctcatat caaatttata gtagattgaa actagaatag tacaccttta cttctaaaac
    17041 attgttagaa atcgatttga ctgtccttat ttcattttac tatactgtta cgaaattaga
    17101 tatataaatg aaaacttgcc tcaaggtagg ttttttgcta gtagaaaagc gatagacaga
    17161 aattgttgga ctcttaaaaa aatgaagttt tgctcaaaag agctttttaa attaaaacga
    17221 gcaattatca gttcaaatct gtttcaaaag aagaacggat aaattaatcg atgctttgtt
    17281 tttgagttag gaagttaagc atgccaaact gagtcgtagg aataaatttc tttatagaaa
    17341 tgtgttacaa ctctgctata acggaatatt ccttttttgc atttatataa cttatttaac
    17401 actatcttta ttcttgtgat ataatgccaa attatagagt ggaggtcatt taaaatgatt
    17461 gataaagtaa ttgaacaata taaaagtcat gataatcttg atattcgagt agaattgcat
    17521 aagaagtatt caaaaaataa attgggattt aataattgga tattttctaa ctaccaaatc
    17581 actgatgaag taaaggttct agaattggga tgtggtacag gagaattgtg gaaaagtaat
    17641 agtgattcta tagataaaat gaagcagttg attgttacag atttttctaa agatatggta
    17701 aaatcaacga agtcagtgat tggaaataga aacaatgtca attatgagat aatggatatt
    17761 caaaagattt cttttgagaa tgaaactttt gatattgtta ttgctaatat gcttctacat
    17821 catgtgaatg atattcctaa agctctctct gaggtgaata gggtcttaaa aaccggagga
    17881 attttttact gtgctacatt tggtgaaaat ggagttgtaa attatttggc aagtttattt
    17941 aaagatgagg ttaatcaaga tttagaaaat agaacgttta ctttacaaaa tggtaaaagg
    18001 tacctgagta ggtattttaa ctctgtcgat acattactct atgatgatga gttacaggta
    18061 actagtatag atgacctagt taaatacatc caatcgttta aaggaatttc agaaataggt
    18121 tcactagaag aggaaataat acgtaaaaga ttggaaagtg agtttaataa tggtatgttg
    18181 atcattccta aagaatatgg tatgtttatc gctcgaaaag aaagttaagg gaatgaaagt
    18241 gtgaaaaatt acggagaagc ttttcgatat tttagaaaat taaacggata ttctttagag
    18301 tatgctgcag ctgattctat atcaaaatct caactttcta gatttgaaag gggagaaaat
    18361 gaaatttctc tttcaacatt ttttgaatta ttatcaaata tcaatgtttc gatagagaat
    18421 ttttgtaatc acttagaaca ttataaaaga tcggagcgtg atgatttttt ggttaattta
    18481 tctccaaatt tttatagttt gaatattaaa ggattggagg taataaaaaa taagcaacaa
    18541 aaactttttg agaagagtgg aaaaaaactc ataaaataaa tacaattatg gttcagggat
    18601 tatgaaatca gctagattgt aatcatgtag ttagtagaga tgatctaaat ttagtatatg
    18661 actatttatt ccagaaggaa cgatgggagt cctatgagat aacgctgatt ggtaatttat
    18721 atcatctttt tgaaatagat tatatttaca tggtcggaaa agaaatacta gagcgtacac
    18781 attattacga aaaaatcggc aagaatagaa atttagttgt gtcagcttgt ttaaattttt
    18841 ggttctgttg ccttgaaaat tcacatctaa tatatgcaga ctactttgaa atgaaattac
    18901 aaaaat
//
LOCUS       DAVKXA010000039        18897 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKXA010000039 DAVKXA010000000
VERSION     DAVKXA010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.039"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(49..762)
                     /gene="rsmG"
                     /locus_tag="VW883_001525"
     CDS             complement(49..762)
                     /gene="rsmG"
                     /locus_tag="VW883_001525"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0274641.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            856..1416
                     /locus_tag="VW883_001526"
     CDS             856..1416
                     /locus_tag="VW883_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0274642.1"
                     /translation="MTWIILGVIALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLKKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            1418..2317
                     /gene="htpX"
                     /locus_tag="VW883_001527"
     CDS             1418..2317
                     /gene="htpX"
                     /locus_tag="VW883_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0274643.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(2361..3920)
                     /locus_tag="VW883_001528"
     CDS             complement(2361..3920)
                     /locus_tag="VW883_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0274644.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGIGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTE
                     HGLELVNLEDV"
     gene            complement(4335..4475)
                     /locus_tag="VW883_001529"
     CDS             complement(4335..4475)
                     /locus_tag="VW883_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEV0274645.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQVTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            4645..5187
                     /locus_tag="VW883_001530"
     CDS             4645..5187
                     /locus_tag="VW883_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0274646.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            5187..5816
                     /gene="nth"
                     /locus_tag="VW883_001531"
     CDS             5187..5816
                     /gene="nth"
                     /locus_tag="VW883_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0274647.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            6027..6548
                     /gene="pyrR"
                     /locus_tag="VW883_001532"
     CDS             6027..6548
                     /gene="pyrR"
                     /locus_tag="VW883_001532"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0274648.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            6567..7490
                     /locus_tag="VW883_001533"
     CDS             6567..7490
                     /locus_tag="VW883_001533"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0274649.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            7540..8619
                     /gene="carA"
                     /locus_tag="VW883_001534"
     CDS             7540..8619
                     /gene="carA"
                     /locus_tag="VW883_001534"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0274650.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            8932..12108
                     /gene="carB"
                     /locus_tag="VW883_001535"
     CDS             8932..12108
                     /gene="carB"
                     /locus_tag="VW883_001535"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0274651.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPVQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLETGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     regulatory      complement(12324..12412)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12621..13250)
                     /locus_tag="VW883_001536"
     CDS             complement(12621..13250)
                     /locus_tag="VW883_001536"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0274652.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKD
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13252..14034)
                     /gene="thiM"
                     /locus_tag="VW883_001537"
     CDS             complement(13252..14034)
                     /gene="thiM"
                     /locus_tag="VW883_001537"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0274653.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14271..14939)
                     /locus_tag="VW883_001538"
     CDS             complement(14271..14939)
                     /locus_tag="VW883_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0274654.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15154..15242)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15494..16630)
                     /gene="lctO"
                     /locus_tag="VW883_001539"
     CDS             complement(15494..16630)
                     /gene="lctO"
                     /locus_tag="VW883_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0274655.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17255..18745)
                     /gene="lysS"
                     /locus_tag="VW883_001540"
     CDS             complement(17255..18745)
                     /gene="lysS"
                     /locus_tag="VW883_001540"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0274656.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
BASE COUNT         5482 a         3827 c         3839 g         5749 t
ORIGIN      
        1 aaataagaga gcgaggttga ttttgtaaat atttttttac ttaaaaattt aaagcgggcg
       61 tttatttggc ataccagcct tacgtggata tttatttggt gtttcttttt tcttttctac
      121 cactgtgatg taacgcggat ctctatttgg tagggcgtag ctgagattgt cttcgacttt
      181 actaaaaagg agattgaggg cattcttagc ttctaacaac tcctcaggcg cattgctggc
      241 cttgagtgcc aatagttttc caccaacctt aaggtaggga atagtcaatt cagataggac
      301 ctgcatacgg gcaaccgcac gagctgttac aaaatcatat tgagcacgga agttcttgtc
      361 ttgggcaaaa tcttcggcac gtccgtggta gaaatgaact ccgttcaaat ccagttcttg
      421 agccaagagt tgtaggaagt tgatgcgctt attgagtgaa tcaataatgg tcacatctaa
      481 ctccggatag agaattttca ttggtagact aggaaatcct gccccagccc cgatatcaag
      541 aagtttgata gtttcattgg gaatcaaacc ttgaagaatg ggtgcaatcg aatcgtaaaa
      601 atgtttgaga taaacttctt ccttgtccgt aatcgccgtc aaattaatct tctcattcca
      661 ctcgaccaag agctcaaaat aacgttcaaa ttgttctttt tgctggtccg aaagtggaag
      721 attctgctcg gcaagcaagt tgtaaaatgt ttttggtttc atagttattt ccttctttag
      781 tatcatctta ttttaccaca atcatagaaa atttgatata ctggtactaa tctaaaagca
      841 gaaaggactt atattatgac ttggattatt cttggagtta tcgctcttgt tgttattttt
      901 gtgattgtta gctataacgg tttggttaaa aatcgtatgc aaaccaagga ggcttggagt
      961 cagattgatg ttcagttgaa acgtcgcaat gatctcttgc caaacttgat tgagactgta
     1021 aaaggttatg ccaaatatga aggttctacc cttaaaaagg tggcagaact acgtaaccaa
     1081 gtggcggcag cgacttcacc agcagaagct atgaaagcca gtgatgccct cactcgtcag
     1141 gtttcaggta tttttgcagt tgcagaaagc tatccagatt tgaaagctag tgctaacttt
     1201 gttaaattgc aagaggagtt gacaaacaca gaaaataaaa tttcttactc tcgtcaactc
     1261 tataacagtg ttgtcagcaa ctacaatgta aaattagaaa ctttcccgag caatattatc
     1321 gctggaatgt ttggatttaa agcggcagat ttccttcaaa cacctgaaga ggaaaagtcg
     1381 gttcctaaag ttgattttag cggtttaggt gactaagatg ttgtttgatc aaattgcaag
     1441 caataaacga aaaacctgga ttttgttgct ggtatttttc ctactcttag ctcttgttgg
     1501 ttatgcggtt ggttatctct ttataagatc tggacttggt ggtttggtta tcgcactgat
     1561 tatcggcttt atctacgctt tgtctatgat ttttcaatcg acagagattg tcatgtccat
     1621 gaatggagcg cgtgaggtgg atgagcaaac ggcaccagac ctctaccatg tagtggaaga
     1681 tatggctctg gtcgcccaga ttcctatgcc ccgtgttttc atcattgatg atccagcctt
     1741 aaatgccttt gcgacaggtt ctaatcctca aaatgcggct gttgctgcga cttcaggtct
     1801 actagctatc atgaatcgtg aagaactaga agctgttatg ggacatgaag tcagtcatat
     1861 tcgtaattat gatatccgta tttcgactat tgcagttgcc cttgctagtg ctatcaccat
     1921 gctttctggt atggcaggtc gtatgatgtg gtggggtgga gcaggtcgca gacgaagtga
     1981 tgatgaccga gatggaaatg gtcttgaaat cattatgcta gtggtttccc tactagctat
     2041 tgtactggca cctctcgctg caaccttggt tcagctcgct atttctcgtc agagggaatt
     2101 tctggcagat gcatctagtg tcgagctgac tcgcaatccc cagggaatga ttaatgccct
     2161 agataagttg gacaatagta aacctatgag tcgccacgtc gatgatgcta gcagtgctct
     2221 ttatatcaat gatcccaaga aaggtggggg gttccaaaaa ctcttttata cccacccacc
     2281 tatctcagaa cggattgaac gtttaaaaca gatgtaaaag aatccagagg tcgtctctgg
     2341 atttttgcta tgttgcaaat ttatacatct tctaaattaa ctaactccaa accgtgttct
     2401 gtcaagcggt agatgcttga acagacctct tttaagaaac gacggtcatg cgaaacagtg
     2461 atgagaccgc ctggataggt tgcaaagagt tttctgattt ggggttgaga agtgggagaa
     2521 aagtttcgtg tgggttcatc cagcaggaga aagtttggtt tgcgcaggac taaatccaaa
     2581 agcaggagtt ttccctgttg tccgccagat aaggagcgaa tttgatgctg catttctgga
     2641 taactgaaat tgagactggc taggtgagat tggattttct gaagttcctc tttttcccca
     2701 gttttgctga tataagctat tgaggataaa tccaattgca gttttttgtg gtaatcttgt
     2761 ggcataaaac caagtgaaat ctctctttta tcattaagaa gttgctgtaa tttggctaac
     2821 agagttgatt tcccaatacc atttgggccg atgataccga ttttttcttg gccacggaca
     2881 gttagttgca gttcctgagc caaaacacgg tcgtcaatgg acaaattttc tttttccagt
     2941 tggactaaga ctttagaagc tggtaatggt tggatgtctg aaaagaaaag ttggatttgt
     3001 tcctcttcaa gtggcttttg agtcatggac tgagctgtct tttcgtagcg tttttcttgt
     3061 gagaggacag ttttcatctt tttagccaat aggcgaccgg cagtactatc tttggtagct
     3121 cgaagcgcag tttctacatt ttgcttaact ctccgatgtt tttccatggt tttatcgtag
     3181 gctctttggt tgttagcagc ttgctgactt tgtttggcaa aattagcctt tctctgctca
     3241 ctatagctat catagtctaa atgctctact agcgtttccg cttctttacg gtgtttgacc
     3301 agtcgcaagt ggacaatagt gtctgccgtt tcagaaagaa agtcttcatc atgggaaatg
     3361 aaaataacgg tttgcctggt cttttgaatc tggcctttta gccaatcaac tgtctcaagg
     3421 tctaggtcat ttgaaggttc atctaaaaat agaatctcaa agggtttggc taactcatgg
     3481 ataagctgaa ttttcaaagc ttcgccccct gatagattgc caatctcttg gtcacttgcg
     3541 aaacgattgc tatcaaaatg caattcctcc gccaaacgat agaggatact gtagtctaaa
     3601 tcaatagaat ctaaaaagaa gtagtcgtgt aaagttttct tttttaggtc ctcagggact
     3661 ttttgaggaa tgtaggccag tgactgataa tcagactgga tgtctccctt gatagtgaaa
     3721 tcagacaaat cttcccccat taaagtttta agtaaggttg atttaccatt tccttcttcg
     3781 ccaataatag ctaccttttc cccgtcttgt atggtcatgc ttaggtcaga gacaaggtct
     3841 cgtaaatctt tgttttgtgt gatggtcagg tgattgattt ttatcatatg atttcccttt
     3901 ctagaatgtt catagtgcat aacaaaaagt tctactttac ctagtagagc ccaaagtcta
     3961 tgtcaaaaaa actctattaa catgccagaa aaagagcata aaagagcaca caaaaagaga
     4021 caaaaacaag atctactaaa taaaggttct ttatttgata gacttagttg ttcatgtctc
     4081 ccttacctcc gagtattagt atctttatat tataccttta aggaaatttt gtcaacagaa
     4141 aactggaaat tctatgctct aaaatccaaa aacaggtcca tagagactta gtacgtgttt
     4201 gacatactcg taatggattt tatcatagtt tcgccaagca gtgcgtgctt gattgtttag
     4261 ttttaggcta cccagtccaa tcagaggact ggtgggttgg taaaatttct caagattaat
     4321 taagatactg ttgttcaact tttctgtttt ttgagctctt gcatagtagt gtttagcagc
     4381 tcttgtagtc gaatatcatc tgccgtaacc tgtttacagt tttggtagct tttatttaac
     4441 ttggatagga gttgaatgag tttcttgtct tccatgtgag catcctcctt gatctgatgt
     4501 actctttccc tatagtatag cactaaaaaa taaaactatc atagtaaata tgttaaaatt
     4561 ttgaatttta attacaaagt ttggtgtgct gatttgtagc cttttcatgg tataatcaag
     4621 agagtaaatc tttatggagg aagtatgaaa ttaaatattc aagaaattcg taagcagtct
     4681 gaaggtttga actttgaaca aacgttagat ttagttgatg acctgcgtgc acgtaatcaa
     4741 gaaattttag atgtaaaaga tatccttgca gttgggaaag tacaatatga agaccgtatg
     4801 tatttcttag attatcaact atcttatacc attgttcttg cttcgagtcg cagtatggag
     4861 ccagttgagt tagttgaatc ttatccagtc acggaagttt tcatggaagg cgcaactaac
     4921 cagctagatc aagaagtttt agatgatgac ttggtcttgc ccatcgaaaa tggggcgctt
     4981 gaccttgctg agagtgtatc agacaatatc ctgctaaaca ttcctatcaa ggtcttgacg
     5041 gctgaagaag aagctggtca aggatttgtc tcaggaaatg actggcaaat catgacagag
     5101 gaagaatacc aagctcaaca agcagtaaag aaagaagaaa acagtccttt tgctggctta
     5161 caaggactat ttgacggaga tgaataatgg tcttgtcaaa aaaacgagca cgaaaggtgc
     5221 tagaagaaat cattgccctc ttcccagatg ccaagcctag tcttgatttt accaatcatt
     5281 ttgaactcct ggttgcggtc atgttatcag cccagacgac agatgcagcg gtaaataagg
     5341 ccacaccagg tctctttgtt gcctttccaa caccccaagc tatgtctgta gcgacagaga
     5401 gtgagattgc ttcacatatt tctcgcttgg gattgtatcg gaataaagct aaattcctta
     5461 aaaaatgtgc ccaacagtta ctagacgatt ttgatggtca agtccctcag acacgtgaag
     5521 aattggagag tttggcaggt gttggtcgca agacagccaa tgttgtcatg agtgtaggat
     5581 ttgggattcc agcctttgca gtggatactc atgtggagcg tatttgcaaa caccacgata
     5641 ttgtcaaaaa atcagcgacg ccacttgagg tggaaaagcg ggtcatggat atcttgccgc
     5701 ctgagcagtg gttagctgcc catcaggcca tgatttattt tggaagagcc atttgccatc
     5761 caaaaaatcc agagtgtgac cagtacccac aattatatga ttttagcaat ttgtaagatg
     5821 ctacattgaa actttttgct tgattttaag catgctttgt gctatagtaa atgataacta
     5881 aatattcctt taaacctgtc ccgtgaggca ggcaaggagc gcgataaagt agaagggtga
     5941 agtctatact gtgttcagta gggctcgctt ggctataaat ttcaagtctc cttgtttaag
     6001 gagacttttc tttttggagg tttgtcatga aaacaaaaga agttgtagac gaattgaccg
     6061 tcaaacgagc gattacgcgt attacttatg agattatcga acgcaacaaa gatttgaata
     6121 agatcgtctt ggctggtatt aaaactcgtg gtgtctttat tgcccaccga atccaagaac
     6181 gtttgaagca gttagaaaat ctttcagttc ctgttgtgga attggatact aaacctttcc
     6241 gtgatgatgt taaaagtgga gaagatactt ctttggtttc tgtcgatgtg acagaccgcg
     6301 aagttatctt ggtggatgat gtgctctata caggtcgtac catccgtgct gctattgata
     6361 atattgtcgg tcatggtcgt cctgcgcgtg tgagtttagc agttctagtc gatcgtggac
     6421 atagagaatt gccaatccgt ccagattacg ttggaaaaaa tatcccaacc agtcgttctg
     6481 aagaaatcat cgtagagatg acagaacttg atgaccaaga cagagttctg attactgaag
     6541 aagcttagaa agttaaagga gtagccatgt cagaaaatca acaagcattg aaccatgtgg
     6601 tgtccatgga agacctcact gtcgatcaag taatgaaatt gatcaagcga ggaattgagt
     6661 ttaaaaatgg agcccagctt ccctatgaag accatccgat tgtttccaat ctcttctttg
     6721 aggattctac acggacacat aagtcctttg aagtcgcaga gattaaactt ggattggaac
     6781 gacttgactt tgatgtgaag actagctcgg ttaataaggg tgagacactt tatgacacca
     6841 ttttgactct gtctgcttta ggagtggatg tctgtgtgat tcgccatcca gaggtcgact
     6901 actatagaga attgattgct agtccaacga ttacgacttc catcatcaat ggtggagatg
     6961 gttcgggcca acaccctagc cagagcttgc ttgatttgat gaccatttat gaggaatttg
     7021 gccactttga gggtcttaaa gttgctattg caggtgactt ggaccactca cgcgttgcca
     7081 aatccaatat gcagattttg aaacgcttgg gagctgaact ctttttcgct ggacctgagg
     7141 aatggagaag tcaagagttt gcagactatg gaaagtttgt aaccattgat gaaatcattg
     7201 atcaggttga tgtcatgatg tttctccgtg tgcaacacga acgccatgat agtggagctg
     7261 tattttcaaa agaagactac catgcccaac atggcttgac tcaagaacgt tacgatcgtt
     7321 tgaaagaaac agcaatcctc atgcacccag ctccaatcaa tcgtgatgta gaaatagcag
     7381 accacttggt tgaagcacca aaatcacgga ttgtccaaca aatgaccaat ggtgtctttg
     7441 ttcgaatggc aatcttagaa tccgtactag cgagtagaaa cgccaactaa aacacaagac
     7501 gttaaaagac gccagtgagc gtccacgaga ggtgaaaata tgacaaaaag aattctagta
     7561 ttagaagatg gcacagtttt tgaaggcaag gccttcggag cagatattga tgtaacaggc
     7621 gaaatcgtct ttaatacagg gatgaccggc taccaagaat ccattacaga ccagtcttat
     7681 aatggacaaa tcttgacctt tacttatcct ttggtaggaa attatggtat taatcgtgat
     7741 gattatgaat ccattattcc aacttgtaag ggagtcgttg tttttgaaga agcgcgtaga
     7801 gctagcaact ggcgcaacca aatgaccttg gatgaatttt tgaaagccaa gaaaattcca
     7861 gggatttcag gaattgatac gcgtgctctt accaagatta tccgtaagca tggtactatg
     7921 cgtgcaacct tgacccatgt tggggacagt atggaccatg tgacggacca gctccaagca
     7981 acagttttac caacagacaa tatcaaacag gtttctacta aaacgtctta tccagctcca
     8041 ggagttggtt taagcgtggt gctagtggac tttggtctca agcactcaat cctacgtgaa
     8101 ctttctaaac gcaactgtaa cgtgacagtt gttccttatt cgacaacggc tgaagaaatt
     8161 ctccatctca atcctgacgg agttatgttg tcaaatggtc caggtaaccc agaagacgtt
     8221 ccacaagcac tcgacatgat tcgcggtgta caaggaaaaa ttccaatctt tggtatttgt
     8281 atgggacacc aactctttgc aatggcaaac ggggctaaga cctataagat gaagtttggc
     8341 caccgtggat tcaaccatgc ggtacgtgaa atcgcaacag gacgagtaga cttcaccagc
     8401 cagaaccatg gttatgcagt cagccgcgag gatttgccag agcacttgat tattacccac
     8461 gaagaaatca atgacaagtc agtggaaggt gtgcgccaca gataccaacc tgctttctct
     8521 gttcaatacc acccagatgc agctcctggg ccacacgacg ctagctacct atttgacgag
     8581 tttatcgaga tgatggaagt ttttaaacaa tcaaactaag aacgagtaaa agctcgtcgg
     8641 agaatttatg taactgaaca cggacggaaa gctcagaatg tagagaaacc aacttggatt
     8701 gtcaatcctt ccttgatttt ctaaaattca atcgctttct attcgtcctt tgtatcttat
     8761 ttaatgtcgc cctgagaggc gacgaataga aaggagaagg gtgctccgta tttgctgaac
     8821 tgaatacggg ctacggacgg tgctaaaaag atagttattc ctagaactga cagttcttcg
     8881 tcataactcc tattttagct ttgtccgctt gacgccctta atatcttata tatgcctaaa
     8941 cgtactgata ttcaaaaaat tatggtgatt ggttctggtc cgattattat tggtcaggct
     9001 gctgagtttg actacgctgg gactcaggct tgcttgtcgt tgaaagagga aggttatgag
     9061 gttgttttgg ttaactcaaa tcctgcaacc atcatgacgg acaaggaaat tgctgacaag
     9121 gtttacattg aaccgattac acttgagttt gtgacacgta ttcttcgtaa ggaacgtcca
     9181 gatgccttgc taccaacact cggtggtcag acaggtctca acatggccat ggaattgtct
     9241 aaaaatggta tcttagatga gcttggcgtt gaacttctgg gtaccaaatt atctgccatt
     9301 gaccaagcgg aggaccgtga cctctttaaa caattgatgg aagagcttga acaacccatt
     9361 ccagaatctg aaattgttaa cacagtagaa gaagcagttg cctttgcagc gacaattggc
     9421 tacccagtca tcgttcgtcc agcctttacc ctcggtggta ctggtggtgg tatgtgtgcc
     9481 aatgagaaag aattgcgtga aatcactgaa aatggtttga aattgtcacc tgttacccaa
     9541 tgtttgattg agcgttcgat tgccggtttc aaggaaattg aatacgaagt gatgcgtgac
     9601 tcagctgaca atgccttggt tgtttgtaac atggaaaact ttgacccagt tgggattcac
     9661 acaggggatt ccattgtatt tgcccctgtg caaaccatgt cagactatga aaaccaaatg
     9721 cttcgtgatg cgagcttgag cattattcgt gccctcaaga ttgaaggtgg atgtaatgtt
     9781 cagctagctc ttgatcctaa cagcttcaag tattatgtta tcgaagtaaa ccctcgtgta
     9841 tcacgttcgt cagcccttgc ttctaaagcg actggatatc cgattgctaa gttggctgcc
     9901 aagattgcag taggtttgac cttggatgag gttataaacc cagttacagg ttcaacctat
     9961 gccatgtttg aaccagccct tgactacgta gttgctaaga ttccacgttt cccatttgac
    10021 aagtttgaaa agggtgaacg ccgtctcggt acacaaatga aggcgactgg agaagtcatg
    10081 gcaatcggtc gtaatatcga ggaatctctt ctcaaggcct gccgctccct tgaaactggg
    10141 gtgcaccaca atgaaatacc tgaacttgca gcagtttctg atgatgcctt gattgaaaag
    10201 gttgtcaaag cccaagatga ccgtctcttc tacgtatcag aagcaattcg tcgtggctac
    10261 acacctgaag aaattgcaga gctaacaaaa attgatatct tctatcttga taaactcttg
    10321 catatctttg aaattgagca agaattgggt gctcatccac aagatctaga agttttgaaa
    10381 acagccaaac ttaatggttt ctcagaccgt aagattgctg aactctgggg aacgactgat
    10441 gatcaagttc gccaacttcg cttggaaaac aagattgttc cagtttataa gatggtagat
    10501 acttgtgcgg cagagttcga ctctgaaacg ccatatttct attcaaccta tggttgggaa
    10561 aatgaatcta tcagatctga taaagaatct gtacttgtcc taggttcagg tccaatccgt
    10621 atcggtcaag gggttgagtt tgactacgca accgttcact ctgttaaggc tatccaggca
    10681 gctggttatg aagctatcat catgaactca aacccagaga ccgtttcaac agacttctct
    10741 gtatcagata agctttactt tgagccattg acattcgaag atgttatgaa cgtcattgac
    10801 ttggaacaac caaagggagt tatcgttcag tttggtggtc aaacagccat caaccttgcg
    10861 gagccattgg caaaagcagg tgtgaccatc cttggtacac aggttgctga cctagaccgt
    10921 gccgaagacc gtgacctctt cgagcaagct ctcaaagaat tggatattcc acagccacca
    10981 ggacaaacgg ctaccaatga agaagaagca gctcttgcag ctcgtaagat tggcttccca
    11041 gttcttgtcc gcccatctta tgtacttggt ggacgtgcca tggaaatcgt tgaaaacgaa
    11101 gaagaccttc gttcttacat gcgaactgct gttaaggcta gtccagatca cccagttctt
    11161 gtcgactctt atatcgttgg gcaagagtgc gaagttgatg ccatttcaga tggtaaagat
    11221 gtactcattc ctggtatcat ggagcatatc gaacgtgctg gtgtccactc aggtgactca
    11281 atggctgttt acccaccaca aaccttgtcg caaaaagttc aggagaccat cgcagactac
    11341 accaaacgct tagcaatcgg tcttcactgc cttggaatga tgaacatcca gtttgttatc
    11401 aaggatgaaa aagtctacgt tattgaggtc aatccacgtg ccagccgtac cgttccattt
    11461 ctatctaagg taaccaatat tcctatggct caagtagcga ccaagctcat tcttggtcaa
    11521 agtttatcag aacttggcta ccaaaatgga ctttaccctg aaagcacccg tgttcatatc
    11581 aaggcacctg tcttctcctt tactaaacta gctaaggtag acagcttgct cggtcctgaa
    11641 atgaagtcaa caggtgaagt tatgggttct gatgctactt tggaaaaagc tctctataaa
    11701 gcctttgaag cttcttatct acacttgcca acttttggta atgtcgtctt taccatcgct
    11761 gatgatgcca aagaagaagc cttgaacttg gctcgtcgtt tccaaaacat tggttatgga
    11821 atccttgcga cagaagggac agcagccttc tttgctagtc atggcttgca agcccaacct
    11881 gttggtaaga ttggtgatga cgataaggat atcccaagtt ttgtacgcaa aggaagaatt
    11941 caagctatca ttaacacagt aggaacaaaa cgaactgctg acgaagatgg tgagcaaatt
    12001 cgtcgttcag ccattgaaca cggggtgccc ctcttcacag cgctagatac agctaatgcc
    12061 atgcttaagg tacttgaaag tcgtagcttt gttacagaag cgatttaaat agaaaaataa
    12121 gatatagcag actgaattta gaacagtaca cagggatact aaaatatttc tagaaattaa
    12181 tttgaatttt ctaattgatt tgttcgcatc ttatttcaat ctactatatc atcttcatcc
    12241 agtttcgtaa aagaaaaaac tctaattaca gatacgaatt agagttcagc ttacaagatt
    12301 agacagttct tttcgacata cgaaaaaaac atttcacatt tcccttcgcc agtcttaact
    12361 gtatcaggtt caatgggtat catctcagcc taaagcaccc caaatgcctt tattatttaa
    12421 ttatgtgatt attataacac acattttata ctagttcaag aaattgaact ggaaatacag
    12481 ccttgcactc acaaagacag cagatctttc ttttgcaaaa aacaaatgac ctgtttgatg
    12541 aattaaccat tcaagctgaa tctagacata gctttttaaa aaaggaaaat cctacttact
    12601 tagaatccaa ggatagatat ctattgctca ctcatttccc gaacagtttt ttctatattt
    12661 tttgcatacg atattgccga aatgattgaa acgccatcca tattggtctt tataatgtct
    12721 ttaatatgtt tcgtctgtat cccaccaatt gcaactaaag gcatttgtgg caatagtttt
    12781 ctcatcaatt caagaccttc ataacctata gcaccaccag catcatcttt tgactgggta
    12841 tcaaatacag gcccaacacc tacataatct acatattcaa cttttgattg ttgaaattct
    12901 tcttcgtttc ttatagaaag accaattatt ttatctggca tcaattttct aatttcatca
    12961 acaccaatat catcttgacc tacatgtacg ccatcggcgt caatttccat tgctaaatct
    13021 atatcgtcat taacgataaa tggaacattg tattttttac aaagttcttt aatttggata
    13081 gctagctcaa gtttttctaa gccttctaaa gcaccctcat ctttttctcg aaattgaaat
    13141 aaggttatac caccttttaa ggcttcctca acgactgtat atagattttt tccttggcaa
    13201 gtagtcgttc cacaaataaa atatagtttt agtaattctt tatgaaacat cttacttcac
    13261 tcttttgaat tcctttacat cttcatctgt aatctcgtat aaggcattta taaattcaac
    13321 tttaaatgtc ccaggaagat gtccatttgg acgtttttct gccatttctc cagcgatatt
    13381 gtaaactaac attgctgttt ctaatgattt caattcttga cctttttcta gtccgataaa
    13441 gcttgctact acagctccta ataagcatcc tgtcccaatg actttcggca tcatagcact
    13501 accattatga atcgttacca cttctccatt aacagcaatg gcatccactt cacctgttac
    13561 tactattgga atattgaact tctcatttgc tgctagagca atctcgtcaa tattatctac
    13621 tcccgcacta tctactcctt tagatgccac atctattcct actaaagagg caatctctcc
    13681 agcattcccc ctaatcgcag ctagtttgta attgttgatt agatcatctg ctactttttt
    13741 tctatattct cctgctccac aggctacagg atctaaaact gctgggacat tatatttctc
    13801 tgcaattttc agagcagctt ggtataattt ccaattttca tctgtcaatg ttcctatgtt
    13861 tattaataaa ccaccagcat actttaataa gtcctctaaa tctgctggaa actcactcat
    13921 ggctggtgag gcgcccagtg ctactaatcc atttgctgtg aaatttttta ctacatcatt
    13981 ggtgatgcaa atgaccaaag gtgctttttc ttttaataat tttaaacttg tcatattgaa
    14041 atccttcctt ttcactttat acgatctact aatttcgatt tatctttagt tgagaatttt
    14101 tttcatttac attgaatgat ttatactcaa tgaaaatcaa agagcaaact aggaggctaa
    14161 tcgcaggttg ctcaaaacac tgttttgagg ttgtggatag aactgacgtg gtttgaagag
    14221 attttcgaag agtcttacct catcaaattt gtaaatatca tgagccttct ctagacatcg
    14281 taaccaatat caaaaaaagc taattctaaa gcgactgctt gattccagcg ttgctgaagt
    14341 tctgtcaaat cttctcgatt tttaccgaca cgattgagtt cgtcaaccag aaattgaacc
    14401 cactctgcaa agaaaggacc tctgtggaga ttgatccatt ccgaatgaat atagacttca
    14461 ggtaaagcca aatctttaga accccagtct aaatagagac cttctgcaat gaccagcatg
    14521 accaaaagat gggcatagtc tgatgaagcc accgccgaat acattagatc ctgaaaggct
    14581 tttgttacag ggtgcaaagt cacttctaga tagtcattct ctgctacttt taactcttta
    14641 aaagcctttt ggaaataacc atcttcatct gcttcaagaa agcctagttg cttggcaaaa
    14701 cgaagcttgg attcaagttt atctgcgtga gctacgcagg cacccagcat ggataagaag
    14761 gcatcaaaga agtgataatc ttgaatcaga tagtccttta agaccttatt ctcaattgtc
    14821 cccgcaaaaa gttccttaac aaaacgatga ttgattgcag cctgccaatc cttctgactg
    14881 ctttttaata attctccaac agtcaaacct ggctgaaatg catagtcttg tgtttccata
    14941 tttacttctc ctctctttac ttgttagtaa ttaataaaac agcaagaaat atcaagcaaa
    15001 atcgtaattc cacttgatcc ttttaaagca catcgagagc atttacagag agctaactaa
    15061 acaagcctat ccagtttata taaacaaaaa actccaatta caatcaagaa ttagagttga
    15121 cttacaagat tagatcgttc atttcgccat acgaaaaaac gtttcacatt tcccttcgcc
    15181 agtcttaact gtatcaggtt caatgggtat tatctcagcc taaagcaccc caaatgtctc
    15241 tattatttaa ttactgaacc agtatagcaa aaaatgaaag ccctagcaag atatttgacc
    15301 gaaaaatatc tttatatagt agattgaaac tagaatagta cacctctact tctaaaacat
    15361 tgttagaaat cgatttgact gtcctgattg atttgtccta ttcttatttc attttactat
    15421 agttttcgat agcaatttat tcttccaata cacgaagaaa aacctccaca ttcagtggag
    15481 gcaatctgtt ttatcaatac aattttaagt cacgagggtc aactgggaag gttgggttgt
    15541 atggattgtg acggagctta aagtgtttga catcttcaat ggtctgagct ccagacaatt
    15601 gcataactgt cttcaattcc gcattcaagt gttcaaagac ttgacgcaca ccgacactac
    15661 caccgagagc caagccataa ataacagggc gaccaatagc taccaagtct gctcctgaag
    15721 ccaaggcttt aaagacgtgt tgaccacgac gaacaccaga gtcaaagaca atcggcacac
    15781 gtctatcaac tgcttctgcc acttcttgaa gcgagtcaaa ggcagctggt ccaccgtcga
    15841 tttgacgacc accgtggttg gttacccaga taccagaagc tcctgcagca agcgaacgtt
    15901 caacgtcctc acggcattgt ggtcccttga catacacagg aagaccagag tattcagcga
    15961 taaattctac atcgcgtgga gacaagcgtt gtttagctga tttgtaaaca aagtccattg
    16021 atttaccagc accttctggc aggtattctt caacaatcgg catgccaact gggaagacaa
    16081 aaccattacg cttatccact tcacgattcc cccctacagt agcatctgcc gtcaagacaa
    16141 tcgctttata accttcagcc ttcacacggt ccatgatgtg gcggttgata ccgtcatcct
    16201 tactaaagta aaattggaac caatgggggg tcccttgaag ggcttcagaa atctctggaa
    16261 ggtcaacagt agagtaagag ctggttgtat aaagagaacc aaactcatgc acaccacgcg
    16321 cagtcgccac ttccccctgt tcatttgcca atttatgagc cgcaacaggc gccataatga
    16381 ttggtgaaga tagtttttca cctgcaaatt caatctctgt acttggattt tcaacatcgc
    16441 aaagtgtatg aggaacgatg agtttgtggt taaaggcgcg gatattctct ctcaaagtga
    16501 aagtatcttc cgccccacta gcgatatagc caaatgctgc tttaggaata acttgttgcg
    16561 ccattggctc caaatcatag gtattgatga aatctacatg accttctgca ttgcttgttt
    16621 tgtatgacat aaactgtccc ccttaattaa gtaagcgttt gctttttact atacaactat
    16681 aataactctt ttttcaatca ttttcaagag ttttgcttaa aaaccatctt attttttcat
    16741 acaatatact agccctactt tccttaaact ctaaacttta gtctatatta agtgaatcgt
    16801 tgagattttt tgctgccagg catttaaact acttttttat ttgctgattc tatctactaa
    16861 tactataaaa aaacaagtga ataagacacc agaacatcct ctaataggac ctatggactt
    16921 atatcagtcc catatatact gtttaagcaa gatactatcc tagttgacgc taacttccta
    16981 tcccacttat taatttttta tttatagtga atctgaacaa atcaattggg gaatccaagt
    17041 caatttctag tactttttga acagtttcag cgtactatcg taaaatgaaa taaaacatgc
    17101 acaaattgct tagggaattt aaaccaattt ctaagaatgt cttagaaatc aaagtgtact
    17161 atttcaactt caatatacta cacttcattt tctccttaaa ttcagtctct ttttgaatca
    17221 aaaaatcccc tgataagagc cagaggataa gaatttattt cattgttggg aagagcaata
    17281 catcacggat agttgttgta tcagtgagga gcatgcagag acggtcgata ccgattccca
    17341 aaccacctgt tggtggcata ccgtattcaa gggcttcaat gtagtcatag tcgattcctg
    17401 tcgcttcatc atcaccaagt tctttggctt tagcttgggc ttcaaaacgg ctaagttggt
    17461 cgattgggtc gttgagctca gtaaaggcat taccgtactc cttagtcatg ataaagagct
    17521 cgaaacggtc agtaaagcgt tggtcttcag gatttttctt agcgagtgga gatacagcta
    17581 ctggatgtcc atagacaaag gttggttgga ttaaagtttc ttcaacaaac tcttcaaaga
    17641 aggcattgat gatgtgacca acctcagtgt agtgtttctc aactggaact ttcttctcag
    17701 cagcgatagc tttagcttct tccaaagtca tgtcttgcca gaaatcgaca ccagtaattt
    17761 ctctgatagc atccaccata tgaacacgct taaatggttc gttaatcttg atttcagtac
    17821 cttggtagtt aactgggcca tcgcccttaa ctgatttagc agcgtgttgg ataatgcctt
    17881 ccgtcaagtc catgatgtct tggaagtctg cataagcttg gtaaacttcg atagaagtaa
    17941 actcagggtt atgagtagcg tccattcctt cgttacggaa gatacggcca atttcataga
    18001 cacgttccat accacccacg ataaggcgtt ttaagtgaag ttcagtcgcg atacgaagca
    18061 ccatgtcaat gttttgggca ttgtggtggg tgataaatgg acgggcagca gcaccaccag
    18121 cttcgttgtg aagaacaggt gtttccactt caaggaatcc tttttggtca aggtaacgac
    18181 ggatttcaga gatgattttt gaacgagtga caaaacgttc aaagctttca cgattagaaa
    18241 tcaagtcaag gtaacgttta cggtaaattg tttcaacgtc tgtcaaacca tggaatttct
    18301 caggaagagg acgaagagcc ttagacaagt gtgtgatgtg ggttgccttg atagagagtt
    18361 ctcccatatc cgtacgcatc acttcacctt cgacaccaag gaagtcacca agatctgctt
    18421 ttttgaagat ttcgtagttt tcttcaccga cagcatcctt acgaacgtag atctgaatct
    18481 ggccttcgcg gtcttgaagg tgggcaaaac caacttttcc tttaccacgt ttggttatca
    18541 agcgtcctgc gatagtagct gtttcgtttt tatcgtgtaa ttgttcttta tcgaggttgg
    18601 catatttatc ttttaattct tgtgaatttg cagtacgttc aaaacgtttt ccgaaaggat
    18661 cgattccttg ttcgcggagc gcagccattt tttcacggcg aacgatctgc tggtcattta
    18721 gttcttccat atgttctgta gacatgggat cctcctagtt ttactcaaaa ttgaatacga
    18781 tgagtcattt tttgcgatac tcccatttta tcataaataa gcaagaaatt cacggataat
    18841 ctttaaaaac taaaaagaac ctgacgctaa aatcactgga aagaagtgaa agtatct
//
LOCUS       DAVKXA010000040        18827 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKXA010000040 DAVKXA010000000
VERSION     DAVKXA010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.040"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            154..846
                     /locus_tag="VW883_001541"
     CDS             154..846
                     /locus_tag="VW883_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0274657.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(949..2594)
                     /locus_tag="VW883_001542"
                     /pseudo
     CDS             complement(949..2594)
                     /locus_tag="VW883_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(2584..3675)
                     /locus_tag="VW883_001543"
                     /pseudo
     CDS             complement(2584..3675)
                     /locus_tag="VW883_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3688..4809)
                     /locus_tag="VW883_001544"
                     /pseudo
     CDS             complement(3688..4809)
                     /locus_tag="VW883_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(5026..5223)
                     /locus_tag="VW883_001545"
     CDS             complement(5026..5223)
                     /locus_tag="VW883_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0274658.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSSLSDISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(5298..6074)
                     /locus_tag="VW883_001546"
     CDS             complement(5298..6074)
                     /locus_tag="VW883_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0274659.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            6196..6942
                     /locus_tag="VW883_001547"
     CDS             6196..6942
                     /locus_tag="VW883_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0274660.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNMATLENAGIMVKVVS"
     gene            6955..7935
                     /locus_tag="VW883_001548"
     CDS             6955..7935
                     /locus_tag="VW883_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0274661.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            8130..8450
                     /locus_tag="VW883_001549"
     CDS             8130..8450
                     /locus_tag="VW883_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0274662.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            8496..8804
                     /locus_tag="VW883_001550"
     CDS             8496..8804
                     /locus_tag="VW883_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0274663.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVETEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            8821..10119
                     /locus_tag="VW883_001551"
     CDS             8821..10119
                     /locus_tag="VW883_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0274664.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            10270..12708
                     /locus_tag="VW883_001552"
     CDS             10270..12708
                     /locus_tag="VW883_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0274665.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            12727..13395
                     /locus_tag="VW883_001553"
     CDS             12727..13395
                     /locus_tag="VW883_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0274666.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SCSI"
     gene            13413..14501
                     /locus_tag="VW883_001554"
     CDS             13413..14501
                     /locus_tag="VW883_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0274667.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            14956..17457
                     /locus_tag="VW883_001555"
     CDS             14956..17457
                     /locus_tag="VW883_001555"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0274668.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVAEAAYTEDGLHVNSDFLDGLNKEEA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTRADGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKSVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFVQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKIMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIVVPNKLVNIVVK"
     gene            17651..18346
                     /locus_tag="VW883_001556"
     CDS             17651..18346
                     /locus_tag="VW883_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274669.1"
                     /translation="MPVNEYGQMIGESMEAYTPGELPSFDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVANLEELVTLLNQMLARKDRFYYAIIDKATGKALG
                     TLSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFDELNYRRYEWKCDAL
                     NLPSRRAAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDKDWPKVKSRLEIWLRPENF
                     DKNGQQYKSLREF"
     gene            18358..18774
                     /locus_tag="VW883_001557"
     CDS             18358..18774
                     /locus_tag="VW883_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274670.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPQMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPSYQRQGIGSSLMKQALEDFKEAYQVQ
                     LATEQTEKNVGFYRSMGFETLSTYDCTGMIWVNKEK"
BASE COUNT         5934 a         3014 c         3971 g         5908 t
ORIGIN      
        1 taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat gaactcctaa
       61 actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta ttttatcatt
      121 catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt gtatttggta
      181 cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag cgatactccc
      241 ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg agaatctgat
      301 ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac catgggaatt
      361 atacttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa gcgtatcaga
      421 gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat gggcattatt
      481 cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact ggctgagggc
      541 ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag tggccgaatc
      601 aaggaaggct ttgaaataat tgcaaaagaa atggaagatc aaggtggagg taacgccctt
      661 gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg catgcatccg
      721 catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca gtttagggtt
      781 gaagttgtcg gtgaccgtag ttaccgagag ctaggacgtg agaagatgga agaaggctct
      841 atttaatcag tctagacttg cttgccatga gctagggatt tgataaggat atcaagataa
      901 gaaaaaacag ccgagggtac tcctttcggc tgtttttgat gtggaaaact aaagtgtaat
      961 gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta gaacagtcag
     1021 gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg tataaatagc
     1081 tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga gttttgaaat
     1141 cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca ttggagttgt
     1201 aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt cttcaatact
     1261 tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta atcttctgac
     1321 agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc cacttccaaa
     1381 tagaccagta ttgaaggaag aaatgaaggc aatccctaga acggttcctg gtacaatata
     1441 aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc taacggctag
     1501 gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag ggatacgaat
     1561 ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt ttggagaata
     1621 accttcaaca aataccatac ctgatgtttt taggaaagag gtataaatta agtagatttg
     1681 aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag ccatttttcc
     1741 ttttgtagtt tttttaggct caattggatg gagcagattc atgctgaaac tgtagcggtt
     1801 tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca taattgcaaa
     1861 agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag ggaaagtccg
     1921 atatccttcg ccaatcaaca taggcgttcc aaagtctgag aatgctctca taaatacaag
     1981 caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac gatacgctta
     2041 aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat actgttcatt
     2101 gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac aagtacaatt
     2161 cctttgaatc cataaatatc gatagctgga agataaaggg catttgtcaa aaatttagtg
     2221 atgacctcat ttcgtcctag caagagaacc caggagtagg ctcctacgaa aggagctgac
     2281 atggaagcaa tgataatcaa tatttgtaga aatttctccc ccttgaagtc atacatagag
     2341 aagagataag ctaatagggt tcctacaact aaggaagtga cagtagcggt aatggaaacc
     2401 ttgaaactgt tgactagtgt ctcagagtag tagactttac taaagaaagt gacaaaatta
     2461 gctagtgaga attgtccttc atgtataagt gcttacttga gcacggtaac gataggataa
     2521 acgagaaaga caagataggt aagaaagatg aagaaagagg aggctgtcca aatatttagt
     2581 tttttacgtt ccatggttga ctccttttat caggttttgg gaaccatctg cagaaaagat
     2641 gtttaatttt tgcgtattga ttcgtagacg aatacgattg cctttttgta gatcttcttc
     2701 aaaagttgat tcttcactaa cttgaatttt tgaggcaaaa cctgtctcaa tgaaatactc
     2761 cgtatttagt ccaagataga cgctatcgct aatagttcct tcaatatctc cagattcatc
     2821 tttgataaac tcttcgggac gaatgcttac atgaatagct tgctcctcaa cctgatcaag
     2881 agctagcatt cgaagggcat agccatctga aaagacgata taagcgccgt cgctccgttt
     2941 ttcaagattg gcagggataa tatttgtgcg tccgataaag gttgccacaa actcattagc
     3001 tggtttatga tagagttctt ttggtcggcc gatttgttgg atcaccccat ctttcataac
     3061 agcaatttgg tctgaaatag ccatggcttc ttcttggtcg tgggttacat aaacagttgt
     3121 aattcccact tcgtgttgga tttctcggat ggcttgacgc atatccaagc gaagtttggc
     3181 ctccagatta ctaagtggct cgtccatgag gagaacactt ggattaaccg ctaaggcgca
     3241 tgccaaggtg acacgttgtt gttgtccacc actgagttta tcgggctttc aatccgcata
     3301 ttgagcaatt tgcatgagtt caagatactt gttggtctgt tgaatcaatt cttcttttgg
     3361 aaccttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat gtgggaaaat
     3421 agcgtagttt tggaaaacca gcccgatatt gcgtttgctg ggttccatat tattgatttt
     3481 tgtatcatcg aagtaaaatt ctccatcttt gatactgttg aaacctgcaa tcatacgaag
     3541 aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc cttttggaat
     3601 tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg cgttaataat
     3661 ttcgatctca ctcatagtga acctctttta ctgtttagat tggatatctg taaagacttc
     3721 gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat cttcagtgag
     3781 tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt tacgaacagg
     3841 acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa taaaatcgat
     3901 aaatttcttg gcattttcca tatttttagc ttttttaacg atagcagcac tagcaggtag
     3961 gaagacggtt ccttcttttg gatagactac tttaatgtta gctccgtcat ttaagagttt
     4021 aactgctgga tcctcataag agagaccaac agccatttct ccatcaacga ctgctttata
     4081 gacaccagat gaacttgaac cgattttata gtgtattgaa actagaatag tacacctcta
     4141 cttctaaaac attgttagaa atcgatttga ctgtcctgat taatttgtcc tgttcttatt
     4201 tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc aagccttatc
     4261 atctttgtaa ccaccttgag cttgtagcat atttgttaat tgagcaaagg cgctagaaga
     4321 gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa ggtcgctata
     4381 tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacat taccatctag
     4441 tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat tatcattttc
     4501 ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc
     4561 aaagataaca tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc
     4621 agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg caggaatagt
     4681 tgctccaatt aagccttctg agtttggtca ataaacgact agcgaaccac cgtctccttt
     4741 atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt
     4801 ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac aatgtaagcg
     4861 tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta cactttgact
     4921 gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac atcttatttc
     4981 aattcactat attagagtaa aattctctac aaaaagaaga atagcctatt ttactattct
     5041 tccgagtgat ttcaatttct ttggggaaat atggagatac tttttaaata ctttggcaaa
     5101 atatttatag tctgaaaatc caacttggtc agagatatcg cttaaagagg agttgggaga
     5161 ttcagccatc ttatctatag cttgtttcag gcgatattgt aagatatatt catttagagt
     5221 catggggaag tcttctttga taaccttata tagatgcttg ttatctgcaa atagctagaa
     5281 catttcaagg aaataaacta gaaataacaa ttaatatggt ggttcagaaa taccttttga
     5341 taatcaataa gatcttcagg atgaagtgcg ttgactccat ccatttcata tttccgattt
     5401 aataaacgat atttgttttc accaaattga tgaaaaggga gtagttgaac ttggtcgata
     5461 tttaatgagt taaatagagt agcgaatttt tctgcatcct ctaaactatt gttaaaatta
     5521 ggaataactg ggattcttaa aacgatagtt ttattttgag aaaaagcata atgaatgttt
     5581 ttaataatca tttgattaaa aaccccagtc acttttttat gttttataga attataatgt
     5641 tttaggtctg tgtagataaa atccacatat tgaattaaat caataaattt ttcatgatca
     5701 acaaaggcag tagtttcaat ggcagtgtgt atgtgatgtt ctttagctga ttttaagatg
     5761 gctttagcaa attcaaactg agcaaatatt tcacctcctg ataaagttaa acctccaccg
     5821 gattcttcgt aaaattcttt gtcttttaat acctctgtaa taatttcttc tacagtcttt
     5881 tcttcaccga ctaaggtgaa tttctctcgt tgagcatctt tcattttttc aggtttcatt
     5941 ctttgagatt caggattaga acaccatgga cagcgcagag gacatccttt taaaaaaaca
     6001 gttgtacgaa tacccggacc gtcatgaatt gaaaagtgtt gaatattaaa aataattcct
     6061 ttagatattt ccataagagt tcctcctctt cataagtcta tcctatcaca aaaacgaaag
     6121 aaaaacaatt acgaacgaaa ggttaatttg ttgttttttg ctttttattt tggtagaata
     6181 aaacggaggt gtaaaatgaa aagattggaa caaattatta aattagtatc agaatatgaa
     6241 aagatcgacg ttaatacatt atcggaaaaa ttaaatgtat cgaaagtaac gattagaaaa
     6301 gatttagata aattagagtc aaaaggttta ttacacagag agcatggata tgctgtatta
     6361 aatagtggag atgacttaaa tgtacgtttg tcaattaact atgaaattaa gagaaaaatt
     6421 gttcaggaag cagtaaaatt ggtgtcagat aatgaaacaa taatgataga atctggatcg
     6481 acctgtgctt tacttgctga ggaaatttgc aagcaaaaaa gaaatgttac gattgtaaca
     6541 aattcatttt ttatagcaaa ttttgtgaga gcttatgatt catgtcgtat tattgttctt
     6601 ggtggagagt ttcagaagga ttcacaggtt actgtgggac ctttattaaa agaaatgata
     6661 cagacttttc atgtgcgtca agcttttgtt gggacagatg gctacgataa agagatgggc
     6721 tttacaggaa aagatttaat gcgcagtgag gtagttcaat atatttcagc agcgtcggat
     6781 aaagtcattg tgctaactga ctcaagtaaa tttgataaaa ggggtacagt aagaagattt
     6841 gctttaagtc aagtctatga agtaataaca gacgaaaaac tttctaaaca aaatatggct
     6901 acattagaaa atgctgggat aatggttaag gtagtttcgt aagaggttaa gtgtatgaat
     6961 caagatagga ataaactgct ctctaaaatt gcttatctgt attatattga aaacttaaat
     7021 cagtcacaaa tagcagcaaa attaggaatt tatagaacct ctattagtag aatgttaaca
     7081 gaagcaagga atgcaggaat tgttaaaatt gaaatagaga attttgatac caatatgttt
     7141 aagttggaaa attatgtaaa agaaaaatat ggtctggaaa gtttagaaat tattccaaat
     7201 gaatttgatg ataatccaac aattttatct gaaagaattt ctcaagttgc agcaggtgtc
     7261 cttaggaatc taattgatga taatatgaaa attggctttt cttgggggaa aagtttaagt
     7321 aatttagtag atttaattca cagtaaaagt gtccgaaatg ttcacttcta tcctctagca
     7381 ggtggtccta gtcacataca cgctaaatac catgtgaata cactgattta tgaaatgtct
     7441 agaaaatttc atggagagtg tacatttatg aatgcaacga ttgtgcaaga aaataaattg
     7501 ttagcagatg gtattttgca atcaagatat tttgaaaatt tgaaaaatag ttggaaagat
     7561 ttagatatag ctgtagtcgg aattggtgat tttagcaata aaggaaagca tcaatggtta
     7621 gacatgctta cagaggatga ctttaaagaa ttgaccaaag ttaaaactgt aggagaaatt
     7681 tgttgtcgat tttttgattc aaaaggtaaa gaagtctatg aaaacttaca ggaaagaacg
     7741 atagcaatct ctttggaaga tttaaaaaat attcctcaaa gtttagctgt tgcttacggt
     7801 gatacgaaag tatcttcgat tctttctgtc ttgcgtgcta atttagtaaa tcatttgatt
     7861 acagacaaaa atacaatttt aaaagttttg gaagaagatg gggatttgac ttttagagag
     7921 attctaggtg agtgaaaatg atagactgat tcagtttatc gtttttcttt ttagttgatt
     7981 gcacatttgt gcttatataa acaaaaatag tttatctgtt gtttttggat tgacaacttt
     8041 attatgtagt tgtattctat agttacaaaa gaaaatttta aaatttcaaa tgaaaaaagc
     8101 tttttacata gtgaaatgag gaggaattta tggaaattat tgttccagat caaattatca
     8161 tgggtttaat tttatatgct ggcgatgcga aacaacatat ttataaagca ttagattaca
     8221 taaagaacgg tacatgtgaa cgatgtgaag aagaaatcca gttagctgat gcagccttat
     8281 tagaagctca taatctacaa acaaaattct tggcacagga agcgtctggt acaaagacag
     8341 aaattacagc tctctttgtt cattcacaag atcatctcat gactagtatg acggagatta
     8401 atttaatcaa agaaattatt agtttgagaa aagaacttca taaaaaataa tactagagta
     8461 ttatcattgt tattaacata gaggaggaaa acataatggt gaagattggt ttgttttgtg
     8521 cagcaggttt ttctactggt atgcttgtaa ataatatgaa aattgcagcg caatctagtg
     8581 gagttgagac agaaatagag gcgttttctc agtctaaatt agcggattat gcgccaaata
     8641 tagatgttgc actattgggt ccacaagttg cttatacatt agataaatca aaagaaattt
     8701 gtgataagtg tgatgttccg atagctgtta ttccgatgat ggactatggt atgttagatg
     8761 ggaaaaaagt attagatttg gccctatctt tgattagtgg gtaagaaaag gagatttatt
     8821 atgtcaaaga tggatgttca gaaaatcatt gcaccgatga tgaagtttgt gaatatgcgt
     8881 ggcattatag ctctaaaaga tgggatgtta gcaattttgc cattgacagt agttggtagt
     8941 ttgttcttga ttatgggaca attgccgttc gaaggattaa ataagagcat tgctagtgtt
     9001 tttggagcta attggacaga gccgtttatg caagtatatt caggaacttt tgctattatg
     9061 ggtctaattt cttgtttttc aattgcctat tcttatgcta agaatagcgg agtagaggct
     9121 ttaccagctg gagttctatc tgtatctgca ttctttattt tgctaagatc atcttatatc
     9181 cctaaacaag gtgaggcgat tggggacgct attagtaaag tttggtttgg aggccaagga
     9241 attatcggtg ctatcattat aggtttggta gtaggaagta tttatacctt ctttataaag
     9301 agaaaaattg ttattaagat gccagaacaa gttccacaag ctattgccaa acagtttgaa
     9361 gcaatgattc cagcatttgt aattttctta tcttctatga ttgtatatat tttagcgaag
     9421 tcattgacta atggcggaac attcatagaa atgatttatt ctgctattca agttccgttg
     9481 caaggtttaa ctggatcttt gtatggtgct attggaattg cattctttat atcatttttg
     9541 tggtggtttg gtgttcatgg gcaatcggta gtaaatggag tagtgacagc tctgctttta
     9601 tctaatcttg acgctaataa agctatgtta gcctctgcta atctatcatt agaaaatggt
     9661 gcacatattg ttactcaaca atttttagat tcatttttaa ttctatcagg ttcagggatt
     9721 acgtttggtc ttgtagttgc catgcttttt gcagcaaaat caaaacaata ccaagcctta
     9781 ggaaaagttg cagcttttcc agcaatattt aacgtaaatg agccagttgt atttggattt
     9841 ccgattgtca tgaatccagt tatgtttgta cctttcattc ttgttcctgt acttgcagct
     9901 gtgatagtat atggagctat tgcaacaggt ttcatgcagc cattctcagg ggtaacattg
     9961 ccttggagta caccagctat tctatcagga tttttggtgg gtggatggca aggtgttgtg
    10021 actcagttat tagtattggt gatatctaca gtggtttact ttccattctt taagatacaa
    10081 gatcgtttag cttaccaaaa tgaaatcaaa caatcttaga ggtatttgtg tgttactgtt
    10141 aaactcacac atttgtgcta aaaattagag agttaaaatt tttctagtta aaagcttgaa
    10201 aatttctata aaaatcggta ttatattttc gaaagaaata aaaatatttt cgaaagaaag
    10261 gtgcttacga tggtaaatac agaagtagca agaacaacaa tcaagacaga atattttggc
    10321 agccttactg aaaggatgaa caaatatcga gaagatgttt taaataaaaa accttatatt
    10381 gatgctgaga gagcagttct agcaacacgc gcctatgaac gatacaagga acaacctaat
    10441 gtcctaaaac gtgcatatat gctgaaagaa attttggaaa atatgtctat ctatattgaa
    10501 gaagaatcta tgattgcggg aaatcaagct tcttccaata aagatgctcc tatttttccg
    10561 gaatatacgc tagaatttgt tctcaatgag ttggatcttt ttgaaaagcg tgatggagat
    10621 gttttctata ttacagaaga aacaaaagaa caacttagaa gtattgctcc gttttgggaa
    10681 aataataatt tacgtgctag agctggtgcc ttattacctg aagaagtgtc agtttatatg
    10741 gaaacaggat tcttcggtat ggaaggtaag atgaattctg gagatgctca cttagcagtt
    10801 aactatcaga aacttttgca atttggttta agaggttttg aagagcgggc tcgtaaagca
    10861 aaagtagctc tagatttaac agatccagca agtattgata aatatcattt ttacgactct
    10921 atatttatcg taatcgatgc tattaaagta tatgcaaagc gctttgttgc tcttgctaaa
    10981 agtttagccg aaaatgcaaa tcctaaacgt aagaaagaat tacttgagat tgcagatatt
    11041 tgctctagag tcccatatga accggcaact acttttgcag aagctattca atcagtttgg
    11101 tttattcaat gtattttaca aattgaatct aatggccact ctctttcata tggccgtttt
    11161 gatcaatata tgtatccata tatgaaggct gatttagaaa gtggtaaaga aacagaagat
    11221 agcattgttg aacgtctgac aaatctttgg attaagacaa ttacaattaa taaggttcgc
    11281 agtcaatcac atacattttc ttcagcagga agtcctttat atcaaaatgt tacaattggt
    11341 ggacagactc gagataagaa ggatgctgtt aacccattat cttatttggt attaaaatca
    11401 gttgcacaaa cccatctacc gcaacctaat ctaactgtac gttaccatgc aggtttagat
    11461 gctcgtttca tgaatgagtg tattgaagtg atgaaacttg gttttggtat gcctgcattt
    11521 aataatgatg agattattat tccttctttt attgcaaaag gagtattgga agatgatgct
    11581 tatgattaca gtgccattgg atgtgttgaa acggcagttc cagggaaatg gggctatcgt
    11641 tgcacaggta tgagttatat gaacttccct aaggttctac ttatcacgat gaatgatgga
    11701 attgatccgg cttcgggtaa acggtttgca ccaagctttg gtcattttaa ggatatgaag
    11761 aacttttctg aattagaaaa tgcttgggat aaaacactaa gatatttgac acgaatgagt
    11821 gttattgttg aaaattctat tgatttatca ttggaacgag aagttcctga tattctatgt
    11881 tcagcattga ctgatgattg tattggtcgt ggaaaacacc ttaaagaagg tggagcagta
    11941 tatgattata tatcaggatt gcaagttgga attgcaaatt tgtcggattc attagctgca
    12001 attaaaaaat tggtgtttga ggaagaacgt ataagcccaa gtcagctttg gcatgcactg
    12061 gaaacagatt atgccggaga agaaggtaag gtcattcaag aaatgttgat tcatgatgca
    12121 cctaagtatg gtaatgatga tgattatgct gacaaattgg ttactgctgc ttatgacatt
    12181 tatgttgatg aaattgctaa atatcctaat acacgttatg gaagaggtcc aattggagga
    12241 attcgttatt caggaacatc ttctatctca gccaacgtag ggcagggacg tggaacatta
    12301 gcaactccag atggacgcaa cgcgggtaca ccgttagcag agggttgttc accatcacat
    12361 aatatggatc aacacggccc tacatctgtt ttaaaatctg tttcaaaatt accaacagat
    12421 gaaatcgtag gtggggttct cttaaatcag aaagtaaatc ctcaaacgtt agccaaagaa
    12481 gaagataaat taaaactaat tgctttgtta cgaacattct ttaatcgttt acatgggtac
    12541 catattcaat acaatgttgt ttccagagag acgctgattg acgctcagaa acatcctgaa
    12601 aaacacagag acttaattgt tcgtgttgca ggatactctg cattcttcaa tgttctttct
    12661 aaggcaaccc aagatgacat tataggacgt actgagcata ctttgtaaaa taaagaggtt
    12721 ctttttatgg aatttatgct tgacacatta aatttagatg agattaaaaa gtggtctgaa
    12781 attttgccgc tagctggggt aacttcaaat cccactattg caaaaagaga gggttctatt
    12841 aatttttttg aacgaatcaa agatgtaaga gaattgattg gctctacacc ctctattcat
    12901 gttcaggtga tttctcaaga ttttgaaggc atcttaaagg atgctcatga aattcgaaga
    12961 caagcaggag atgatatatt tatcaaagta cctgttactc cagctggatt acgtgcaata
    13021 aaggtgctaa aaaaagaggg ctaccatatc actgcaacag ctatttatac agttattcag
    13081 ggattattag ctatcgaagc aggagcggat tacctagctc catattataa tagaatggaa
    13141 aatctgaaca ttgattcaaa ttctgtcatt cgtcaattag ctcttgctat tgatagacag
    13201 aactctccta gtaagatttt agctgcatcc tttaaaaatg tagcacaagt aaataatgct
    13261 ttagctgcag gtgcgcatgc tgttacagca ggagcagatg tttttgaatc agctttcgcc
    13321 atgccatcta tccaaaaggc ggttgatgac ttttctgacg actggtttgt tattcaaaat
    13381 agttgttcca tttagataga gaggaaatac atatgagaat ttttgctagt ccttctagat
    13441 atattcaggg ggaaaatgcc ttgtttgaaa atgccaaatc aattttggat ttgggaaatt
    13501 gccctattct attatgcgat cagttggttt atgatattgt tggaaaacga tttgaagatt
    13561 acctacatag gtatggtttc catattgttc tggcgctatt taatggtgaa gcttctgaca
    13621 atgaaatcaa tcgagttgtt gccttggctg agaaagaaaa ttgtgatagt attatcggtc
    13681 ttggtggggg aaagacgatt gatagcgcaa aagctattgc agatttgatt gaaaagcctg
    13741 ttattattgc tccaacaatt gcatcgaccg acgcacctgt atctgcttta tctgttattt
    13801 atacagatga aggtgcattt gatcattatc tattttattc taaaaatcca gatttagttt
    13861 tggttgatac aaaagttatt tcacaagccc ctaagcgttt attagcgtct ggtattgcag
    13921 atggtttagc aacttgggtt gaggcgcgtg cggttatgca ggcaaatgga aaaactatgt
    13981 tgggacaaca gcaaacattg gctggagttg caattgcgaa gaaatgtgaa gaaacgctgt
    14041 ttgcagatgg tttacaggct atggcagctt gtgaagctaa agtggtgaca ccagcattag
    14101 aaaatattgt tgaagctaat actttattga gtggcctagg ttttgaaagt ggaggattag
    14161 ctgcggcgca tgcaattcat aatggtttta ctgcattgac aggtgacatt catcatttaa
    14221 cacatggtga aaaagtagct tatggaactt tagtacaact attattggaa aatagaccta
    14281 aagaagaact tgataagtat attgagtttt acaaaaaaat tggtatgcca acaactctaa
    14341 aagaaatgca tttggatcaa gttggatatg atgatttaat aaaagttggt aaacaagcaa
    14401 ctatggaggg tgagacaatt catcagatgc cgtttaagat ttcgccttca gatgttgctc
    14461 aagctattat cgctgtagat gcctatgtaa attcaaaata aacaataagg actactgttt
    14521 tccaaatggt agtcttttat tgatcctcgt attgaattct atagcagatt gaaataagat
    14581 gagaacaaat cgattgggaa agtaaaatta atttctataa atgttttagc aattgtttcg
    14641 tactatttca gattcagtcc actatacgtt cttcataaat caaaaagcga cataggttgt
    14701 cggctattta ttgtgaatac attaattagc attccagttt tatcttcggt ctaaaataag
    14761 tattttgtgc tatacgagat aagcttcttg acttactcct tgatttactg cataacaatg
    14821 ggataaaaag tgggagatag agcaattcat agtcatcaaa attaatgaga tacagtatac
    14881 agtttttcct ttaaacacat ttcaaattcc ctcaaaaatg gtataatagt aacatcacaa
    14941 aattggagag agaccatgag tttttacaat cataaagaaa ttgagcctaa gtggcagggc
    15001 tactgggcag aacatcatac atttaagaca ggaacagatg catcaaaacc taagttttat
    15061 gcgcttgata tgttccctta tccgtctgga gctggtctgc acgtaggaca cccagaaggt
    15121 tatactgcaa ccgatatcct cagtcgttac aaacgtgcgc aaggctacaa tgtccttcac
    15181 ccaatgggtt gggatgcttt tggtttgcct gcagagcaat acgctatgga tactggtaat
    15241 gacccagcag aatttacagc ggaaaacatt gccaacttca aacgtcaaat caatgcgctt
    15301 ggattttctt atgactggga tcgtgaagtt aacacaacag atccaaacta ctacaagtgg
    15361 acgcaatgga ttttcaccaa gctttacgaa aaaggcttgg cctatgaagc tgaagtgcca
    15421 gtaaactggg ttgaggaatt gggaactgcc attgccaatg aagaagtgct tcctgacgga
    15481 acttctgaac gtggaggcta tccagttgtc cgcaaaccaa tgcgccaatg gatgctcaaa
    15541 atcacggctt acgcagagcg cttgctcaat gacttagatg aactagattg gtcagagtct
    15601 atcaaggata tgcaacgcaa ctggattggt aaatcaactg gtgccaatgt aactttcaaa
    15661 gtaaaaggaa cagacaagga atttacagtc tttactactc gtccggacac acttttcggt
    15721 gcgactttca ctgttttggc tcctgaacat gaattagtag atgccatcac aagcacagag
    15781 caagcagaag cagtagcaga ctacaaacac caagccagcc ttaagtcaga cttggctcgt
    15841 accgaccttg ccaaagaaaa aactggtgta tggactggtg cttatgccat caatcctgtc
    15901 aatggtaagg aaattccaat ctggattgcg gattacgttc ttgctagcta tggtacaggt
    15961 gcggtaatgg ctgtgcctgc ccacgatcaa cgtgactggg aatttgccaa acaatttgac
    16021 cttccaatcg tcgaagtgct tgaaggtgga aatgtagcag aagctgccta tacagaggat
    16081 ggtcttcatg tcaattcaga cttcctagat ggactcaaca aagaagaagc tattgccaag
    16141 attgtggctt ggttggaaga aaaaggctgt ggacaagaga aggttaccta ccgtctccgc
    16201 gactggctct ttagccgtca acgttactgg ggtgaaccaa ttcctatcat tcattgggaa
    16261 gatgggactt caacagctgt tcctgaaagt gaattgccac ttgtcttgcc tgtaaccaag
    16321 gatatccgcc cttcaggtac aggggaaagt ccattggcta acttgacaga ttggcttgaa
    16381 gtgactcgtg cagatggtgt caaaggtcgt cgtgaaacca acactatgcc acaatgggca
    16441 ggttcaagct ggtactacct ccgctatatt gacccacaca atactgagaa attggctgat
    16501 gaggatcttc tcaaacaatg gttgccagta gatatctacg tgggtggtgc agagcatgct
    16561 gttcttcact tgctctacgc tcgtttctgg cataaattcc tctatgacct cggtgttgtt
    16621 ccaactaagg aaccattcca aaaactcttt aaccaaggaa tgattttggg aacaagctac
    16681 cgtgaccacc gtggggctct tgtggcaacc gataaggttg aaaaacgtga cggttctttc
    16741 ttccatgtgg aaacaggaga ggagttggag caagcgccag ccaagatgtc taaatctctt
    16801 aagaatgttg tcaacccaga cgatgtggtg gagcaatacg gtgccgatac ccttcgtgtc
    16861 tatgaaatgt ttatgggacc acttgatgct tcgattgctt ggtcagaaga aggtctggaa
    16921 ggaagccgta aattccttga ccgtgtttac cgtttgatta caagtaaaga aatccttgcg
    16981 gaaaacaatg gcgctcttga taaggtttac aatgaaacag tcaaatctgt cacagagcaa
    17041 attgagtccc tcaaattcaa caccgccatt gcccaactta tggtctttgt caatgcggct
    17101 aacaaggaag acaagctcta tgttgactac gccaaaggct tcgttcagtt gattgcacca
    17161 tttgcacctc acttggcaga agagctctgg caaacagttg cggcaacagg tgagtcaatc
    17221 tcttacgtga cttggccaac atgggatgaa agcaaattgg ttgaagacga aatcgaaatc
    17281 gtcgtccaaa tcaaaggtaa agttcgtgcc aaaatcatgg ttgctaaaga cctatcacgc
    17341 gaagaattgc aagagattgc tctagctgat gaaaaagtca aagcagaaat tgatggtaag
    17401 gaaatcgtga aagtgattgt ggtaccgaat aaattggtta atattgttgt gaaataacca
    17461 atttatttgc tggtttcaaa tctcggacag tttcctaaac tgtttgagcc agttaaactc
    17521 gttaatattg ttttgaaata agataggagt ccttcagagt agaatctggg ggattttttg
    17581 aatcttctta tgaaagtatg atatactatg ggcaactata aagtttgaaa agtgaaataa
    17641 ggagaataag atgccagtaa atgaatatgg tcaaatgatt ggggagtcaa tggaagctta
    17701 tactccaggt gaattgcctt cttttgattt cttagaaggg cgttatgctc gaatagaagc
    17761 tctttcagtg gaaaagcacg cggaggattt attagctgtt tatggccctg atactcctcg
    17821 ggagatgtgg acctacctct ttcaggagcc agtggcaaat ctggaggagc tggttactct
    17881 tttaaatcag atgttggctc gtaaggaccg tttttactat gcaattatag acaaggcaac
    17941 tggtaaggct ttgggaactt tgtctctcat gcgtattgac cagaataacc gagtaataga
    18001 agtgggagct gtcacttttt ctccagagct cagggggaca cggataggaa cagaagctca
    18061 gtatcttttg gctcgctatg tctttgatga gcttaactat cgtcgctatg agtggaaatg
    18121 cgatgctctt aacctgccat ccagacgagc tgcggagcgt ttgggatttg tctacgaagg
    18181 aacctttcgt caggcagtgg tttataaggg gcgtacgagg gatacggatt ggttgtctat
    18241 gattgataag gactggccta aagtcaaatc tcgtttggaa atatggttgc gtcctgaaaa
    18301 ctttgataaa aatggacagc agtacaagag cttgagagaa ttctaagagg tgttgagatg
    18361 attactatta aaaagcaaga aattgtcaag ctagaggatg ttttgcatct ctatcaggct
    18421 gtcggttgga caaattatac ccatcaacct cagatgctgg agcaggcctt gtctcattca
    18481 ttagtaattt atctggcgct tgatggcgat gctgtggtgg gcttgattcg tttggttgga
    18541 gatggttttt catcagtttt tgtacaggat ttgattgttt tacctagcta tcagcgccaa
    18601 gggattggta gctccttgat gaaacaggct ttagaggatt ttaaagaggc ttatcaagtc
    18661 cagctggcga cagaacagac agaaaaaaat gtaggatttt atcgttctat gggttttgaa
    18721 actttatcca cctatgattg tacaggaatg atttgggtaa acaaagaaaa ataacaaaac
    18781 ttgttttttc ttaagcaaag tttaaggatg gtctagtatt atatagt
//
LOCUS       DAVKXA010000041        18783 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKXA010000041 DAVKXA010000000
VERSION     DAVKXA010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18783
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.041"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..90
                     /locus_tag="VW883_001558"
     CDS             <1..90
                     /locus_tag="VW883_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEV0274671.1"
                     /translation="FSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            281..2572
                     /gene="pcrA"
                     /locus_tag="VW883_001559"
     CDS             281..2572
                     /gene="pcrA"
                     /locus_tag="VW883_001559"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0274672.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWHERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2615..3295
                     /gene="radC"
                     /locus_tag="VW883_001560"
     CDS             2615..3295
                     /gene="radC"
                     /locus_tag="VW883_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0274673.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3292..3981)
                     /locus_tag="VW883_001561"
     CDS             complement(3292..3981)
                     /locus_tag="VW883_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0274674.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3999..4640)
                     /locus_tag="VW883_001562"
     CDS             complement(3999..4640)
                     /locus_tag="VW883_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0274675.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4723..4938)
                     /locus_tag="VW883_001563"
     CDS             complement(4723..4938)
                     /locus_tag="VW883_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0274676.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4946..5293)
                     /locus_tag="VW883_001564"
     CDS             complement(4946..5293)
                     /locus_tag="VW883_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0274677.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5298..6413)
                     /locus_tag="VW883_001565"
     CDS             complement(5298..6413)
                     /locus_tag="VW883_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0274678.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6423..7382)
                     /locus_tag="VW883_001566"
     CDS             complement(6423..7382)
                     /locus_tag="VW883_001566"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0274679.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7495..8064)
                     /locus_tag="VW883_001567"
     CDS             complement(7495..8064)
                     /locus_tag="VW883_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0274680.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8192..8863
                     /locus_tag="VW883_001568"
     CDS             8192..8863
                     /locus_tag="VW883_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0274681.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8847..9665
                     /locus_tag="VW883_001569"
     CDS             8847..9665
                     /locus_tag="VW883_001569"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0274682.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9662..10558
                     /locus_tag="VW883_001570"
     CDS             9662..10558
                     /locus_tag="VW883_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0274683.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10602..11576
                     /gene="pta"
                     /locus_tag="VW883_001571"
     CDS             10602..11576
                     /gene="pta"
                     /locus_tag="VW883_001571"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0274684.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11838..13164)
                     /locus_tag="VW883_001572"
                     /pseudo
     CDS             complement(11838..13164)
                     /locus_tag="VW883_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(13345..13644)
                     /locus_tag="VW883_001573"
     CDS             complement(13345..13644)
                     /locus_tag="VW883_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0274685.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            14046..14750
                     /locus_tag="VW883_001574"
     CDS             14046..14750
                     /locus_tag="VW883_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0274686.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     misc_feature    14809..14896
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            14932..15246
                     /gene="rplU"
                     /locus_tag="VW883_001575"
     CDS             14932..15246
                     /gene="rplU"
                     /locus_tag="VW883_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0274687.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            15262..15606
                     /locus_tag="VW883_001576"
     CDS             15262..15606
                     /locus_tag="VW883_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0274688.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            15623..15916
                     /gene="rpmA"
                     /locus_tag="VW883_001577"
     CDS             15623..15916
                     /gene="rpmA"
                     /locus_tag="VW883_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0274689.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(16227..16432)
                     /locus_tag="VW883_001578"
                     /pseudo
     CDS             complement(16227..16432)
                     /locus_tag="VW883_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            16870..17787
                     /locus_tag="VW883_001579"
     CDS             16870..17787
                     /locus_tag="VW883_001579"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0274690.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(17880..18728)
                     /locus_tag="VW883_001580"
     CDS             complement(17880..18728)
                     /locus_tag="VW883_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0274691.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
BASE COUNT         5591 a         3443 c         3958 g         5791 t
ORIGIN      
        1 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgagtgct
       61 ggtattatca atcatgaact aggattctag ttttgcagga agtctattga ggtattgagc
      121 tagtttatga aaaaattggg tgaaaagtcg agtgttttag aaacccacag tgtagtattc
      181 tagtttcaat ccactatatt ttgctactcc ccgtaaagtt tctattttcc ctgatttctg
      241 atataataga aatattgact tcaagagtaa ggaagagaag atgaacgcat tattaaatgg
      301 aatgaatgac cgtcaggctg aggcggtgca aacgacagaa ggtcccttgc taatcatggc
      361 aggggctggt tctggaaaga ctcgtgtttt gacccaccgt atcgcttatt tgattgatga
      421 aaagctggtc aatccttgga atatcttggc cattaccttt accaacaagg ctgcgcgtga
      481 gatgaaagag cgtgcttata gcctcaatcc agcgactcag gactgtctga ttgcgacctt
      541 ccactccatg tgtgtgcgta ttttgcgtcg cgatgcggac catattggct acaatcgtaa
      601 ttttacaatt gtggatcctg gtgaacagcg aacgctcatg aaacgtattc tcaaacagtt
      661 gaacttggac cctaaaaaat ggcatgaacg aactattttg gggaccattt ccaatgctaa
      721 gaatgatttg attgatgatg ttgcttatgc tgcccaagct ggcgatatgt atacgcaaat
      781 tgtggcccag tgttatacag cctatcaaaa agaacttcgt cagtctgaat ccgttgactt
      841 tgatgatttg attatgctga ccttgcgtct ctttgatcaa aatcctgatg ttttgaccta
      901 ctaccagcaa aaattccaat acatccacgt tgatgagtac caagatacca accacgctca
      961 gtaccaattg gtcaaactct tggcttcccg ttttaaaaat atctgtgtgg ttggggatgc
     1021 ggaccagtct atctacggtt ggcgtggtgc tgatatgcag aatatcttgg actttgaaaa
     1081 ggattacccc aaagccaagg ttgttttgtt ggaggaaaat taccgctcaa ccaaaaccat
     1141 tctccaagcg gccaacgagg ttattaaaaa taataaaaat cgccgtccta aaaatctctg
     1201 gactcaaaac gctgatgggg agcaaatcgt ttactatcgt gccgatgatg agctggatga
     1261 ggctgtattt gtagccagaa ccatcgatga acttagtcgc agtcaaaact tccttcataa
     1321 ggattttgca gttctctatc ggactaatgc ccagtcccgt acaattgagg aagccctgct
     1381 caagtctaac attccttata ccatggttgg cggaaccaaa ttctacagcc gtaaggaaat
     1441 tcgcgatatt attgcttatc tcaaccttat tgctaatttg agtgacaata ttagttttga
     1501 gcgtattatc aacgagccta aacgtggaat tggtttaggt acagttgaga aaatccgtga
     1561 ttttgcaaat ttgcaaaata tgtctatgct ggatgcttct gctaatatta tgttgtctgg
     1621 tatcaagggt aaggcagccc aatctatctg ggattttgcc aatatgatgc ttgatttgcg
     1681 ggagcagcta gaccacttaa gcattacaga gttggttgag tccgtcctag aaaaaacagg
     1741 ttatgtcgat attcttaacg cccaagcgac tctagaaagc aaggcacggg ttgaaaatat
     1801 cgaagagttt ctttctgtta cgaagaactt tgatgacacc acggatgtga cagaagagga
     1861 aactggtctg gacaaactga gtcgtttctt aaatgacttg gctttgattg ccgacacaga
     1921 ttcaggtagt caggagacat cagaagtgac cttgatgacc ctgcatgctg ccaaaggtct
     1981 cgaatttcca gttgtctttt tgattgggat ggaagaaaat gtctttccac ttagtcgtgc
     2041 gactgaagat tcagatgaat tagaagaaga gcgccgtcta gcctatgtag gtatcacgcg
     2101 tgcagagaaa attctctatc tgaccaatgc caactcacgc ttgctttttg gtcgtaccaa
     2161 ttataaccgt ccgactcgtt ttattaacga aatcagttca gacttgcttg agtatcaagg
     2221 tctggctcgt cctgcaaata caagctttaa ggcatcatat agcagtggta gtatttcctt
     2281 tggtcaaggt atgagtttgg ctcaggctct tcaagaccgt aaacgcggtg ctgccccaaa
     2341 atcaatccag tcaagcggtc ttccatttgg tcaatttaca gctggcgcaa aaccagcatc
     2401 tagcgaggca aattggtcca ttggtgatat tgctctccac aagaaatggg gagagggaac
     2461 cgttctggaa gtttcaggta gcggtgctag gcaggaattg aaaatcaatt tcccagaagt
     2521 aggtttgaaa aaacttttag ccagtgtggc tccaattgag aaaaaaatct aattttccat
     2581 ccttctcacg aataataaag tgaggaggat ttttatgtac agtatttcat tccaagaaga
     2641 ttcactatta ccaagagaaa ggctggccaa ggaaggagtt gaagcgctta gtaaccaaga
     2701 gttgctagct attttactca ggacaggaac acgtcaagct agcgtttttg aaattgccca
     2761 aaaagtcttg aacaatcttt caagcctaac ggatttgaaa aaaatgaccc tgcaggaatt
     2821 gcagagtttg tctggtattg ggcgtgttaa ggccatagaa ttacaagcta tgattgaact
     2881 ggggcatcgt attcacaaac acgagactct tgaaatggaa agtattctca gcagtcaaaa
     2941 gttggccaag aagatgcagc aggaattagg ggataaaaaa caagagcacc tggtggcact
     3001 ctatctcaat actcaaaatc aaatcatcca tcagcagacc atttttatcg ggtctgtaac
     3061 tcgtagtatc gctgaaccgc gagagattct tcactatgca atcaagcata tggcgacttc
     3121 tcttatcttg gtccacaatc atccttcagg agcggtagcg cctagccaaa atgatgatca
     3181 tgtcactaaa cttgttaaag aagcctgcga attgatgggg attgttctct tggaccattt
     3241 gattgtctct cattctaatt actttagtta tcgtgaaaag acagatttaa tctaaagttc
     3301 attaacgaca tagtcaaaga gttttttatc tttgggacga ttttcaaaaa gaagttctgg
     3361 atgccattgg acaccgagaa aggcgacatc atccgtactc atgacagcct caatgatacc
     3421 atctttagga tcatgagcca caacttttaa atttggtgct aagtccttga tgctctggtg
     3481 gtggaaggag ttgatatgag agatttctcc atagatttct tggagaacgg tatctggttc
     3541 tgttaccaag cgttgagttg tgtactcaac agaagaatcc tgccaatggt cttcgatatc
     3601 ttggtacaaa gttccaccca tggcaacgtt aaagagttgg gtaccacggc agacagagaa
     3661 aatgggcttt ttctgtttaa tagcttcctt gatgagggcc agttcgaaga tatctctttg
     3721 aaggtgatag tcatcactat caatggtttt gggttcgcca taaaattttg gatcgacatt
     3781 ttgcccacct gtcaagatga gcttgtcaat caaactgata tagtggcagg ccatttcttg
     3841 atcaccaatc ggtaagatga tgggaatccc tccagcatct ttaacgcctt caacaaagcc
     3901 ttttgctgcg tagctcatca tgatgtcatc atctggatga gttttttcgt ttcctgtaat
     3961 cccaataact ggttttttca taaaatgatt ttcgctttct aatcctcttt tcgcatgaag
     4021 tagaggaggg tttggagttc acttgtcaaa tcgacatact gaacgaccac gtcttttggt
     4081 aaatgcagat ggactggtga aaaactgaga attcctttca caccagcatc aaccaagaga
     4141 ttagcaacct cttgtgactt gacgctggga acagttagga tagcagtctt cacatcagca
     4201 tccttgattt tatccttgat ctgagaaatc ccgtaaatgg gaatcccgtc aggagtttgg
     4261 gtaccgactt caggatggtc gtctaggtca aaggccatga taatcttcat cttgttacgt
     4321 tcgtggaagc ggtagtggag aagggcatgg cccatatttc caataccaac cagcatgaca
     4381 ttggtaatag agttgtcatt gagcaaatcg gcaaaaaatg tcattagttt tttgacatca
     4441 tagccaaaac cacgacgacc aagttcacca aaataggaaa aatcacgacg tacggtcgct
     4501 gaatcaatac cgatagcctc tgcaatttgc ttagagttgg cacgttcaat cttttctgca
     4561 tgaaatctct taaaaattcg atagtagaga gagagtcttt ttgctgtagc ttttggaata
     4621 gcaaactgtt tatctttcac aaaatcacaa cctttctatt cttctatttt atagaaacat
     4681 tgtgaaaaaa tcaacaaaaa taagaaaaaa ctaagaaaaa tcttagtttt gatgtaaaaa
     4741 atctgcatga gatagaaaac ggtagaggtc tccgaccagc ccctgataaa cttttttgcc
     4801 cctaaaagtc agagaagtca cataaagtgt atctggtaag gttacacatc ctgacaaagt
     4861 caacatgaga gcctcatgat cctcatactt gagagtacgc tctacatgat agcagtcctt
     4921 ataggtcagt tcaaacattt tggctctatc tttccgattt tgtaaagaca ccacgttcta
     4981 ccaagctatc catgaggaag tagaattttt cctgatgaat atggtggtct tctgatttga
     5041 aaatatcaac tagacgaagg ccaaacttgt cagtgatatt gattttagcc cctgtaagtt
     5101 ccttgttaat gatgattttg agttggaagc cttcaccgct gtttggcact ttttccaaaa
     5161 ggcgagtcag ttcatagtta ccaaccttag tttcaaaaaa ggtgttatct ttgagggtga
     5221 attttttaac agaagggcta agagtgtaat cgtaacgaca attttttaac tgaatgattt
     5281 tttcaaatgc catatggcta acctccgata atttctttta aggtttttgc gagggtttgt
     5341 aggtcttcaa cggtattttg tggcgacaaa ctgatgcgaa gggattcctt caagcgttct
     5401 gaatttgcgc catacatggc tttaagaaca tggctggatt ggacaacgcc tgcagtacag
     5461 gctgagccag tagagattga aattccagct aaatctagcc gaaggagtaa gaggtcattt
     5521 ttctgaccag gaaatccaat attgagaaca taagggagat gatgttttcc tctattcaag
     5581 taatactgaa tgccctccag ctctgccaga aaggcagttt ctagattttg tacatgttga
     5641 aaatgttctt cttgtttttc taggtcttct tttagggctg caaccatgcc tacgatggca
     5701 ggcagatttt cagttcctgc acgttttttc tgttcctgat ctccgccatg tagataggaa
     5761 tcaaagtcca tgctagatgc gtagagaaaa ccgattccct taggaccatg gaatttgtgg
     5821 gcagaagcag tgagaaaatc aatgcccaat tcttctgaat gaattgggat tttaccaata
     5881 gcctgaactg catcaacatg ataggcagca gggtgttgct tgagtatttg gccaatttca
     5941 gcgatgggaa gtaggtttcc tgtctcatta ttggcaaaca tagtagaaac caaaatcgta
     6001 tcgtcacgta aagccttttg aatttgctgg gctgtgattt cttgattttc tggctggata
     6061 atggttgctt caaacccaaa gtgttgaacc aagtaatcaa ttgtttcaag gacagcatgg
     6121 tgctcgatgg cagttgtgat gatatgtttt ccttgttctt ggtgacgaag acagtagcca
     6181 atgatggtag tattattgcc ttcagtccca ccagaagtga aaaagatatg ttgaggtttt
     6241 gtccttagta actgggctag ttcctgacgg gcttctcgca agagtttgcc agcttgacga
     6301 ccatgaccat gaatactaga aggatttccg tgggtttctt gcataacctt ggtcatagct
     6361 gaaatagcaa ctgctgacat aggagtcgtt gcagcattgt ccaaataaat caaagaatca
     6421 ccttatttct ttttattgta ggcaaagagt gggctgactg gttttctttc gtgaatacgg
     6481 acgatagcat caccaattaa ctcactagca gtgatgtagc atacattttt aggagttttt
     6541 tcttttgttg ctactgaatc agtcacaaga atttctttaa tattagtatt gtcaagaagc
     6601 tcagcagctc cctcgacgaa gagaccgtgg ctagaaacag cataaatttc tgtagctcct
     6661 tcacgttcaa cgattttaga agcttcagag aaggtacgtc ctgtatttaa aatatcatca
     6721 atcaagatag ctttcttacc ttcaacatca ccaataatat aaccttcgtt acgagttgca
     6781 tcgtcttgag ggtagtcgat aatggcgata ggagcatcaa gatattcagc caggctacgc
     6841 gcacgtttga cacctgaatt tttagggcta acgacaacaa catctgaacc aagcaatcct
     6901 ttatcgcagt aatgttttgc gaatagggga acagtgaaaa gattatccac tggaatatca
     6961 aagaaacctt gaacctgaac ggcatgcaaa tcaagagtca ggatacgatc aactccagcc
     7021 ttaaccagca tattggcaac tagttttgct gtaagtggct cacgaggaca agcaatgcgg
     7081 tcttgacgtg catagccaaa atatggaagg acaacgttga tactgtgggc acttgcacgc
     7141 acacaagcat cgaccatgat taacaattcc attaggtggt tgttgacagg gaaacttgtt
     7201 gattggatga tgtaaacatc ataaccacgg acactttctt cgatatttac ttggatttct
     7261 ccgtctgaaa attgacgtga tgatagtttt ccaagtggga caccaacagc ttgggcaatt
     7321 ttttgtgcaa tctcttggtt agagttgagt gcgaaaagtt tcatgttttt tctatctgac
     7381 attatagacc gtcctctgta aactttataa atcctagtta tatttacctt acatatatga
     7441 actgggattt gtgtattttt atcttttcta ttttaccaaa aaatggagat tatttcagct
     7501 atttttcata cttttgacaa atcgaaccaa ttttgaagga gctttttggt aggaaatctg
     7561 atttttctct aaaaattgtc ggaaatcctg tttgccttgc tcatgatttt ccacttcaag
     7621 ctccaattcg taatctgtca tatcaaagta tcggctctga tccagtgcca tgagaccaat
     7681 agctgttttc atttcatagc gaagcgttgt tagacaacca agaacctgcc agttcttact
     7741 ttggatacca tgtttcgcca attcatccag tactagccct tgaggaagtt cttccttact
     7801 cagatagttc tcagcatctt ttagttgcaa tttttggttg tattccatgt ttccaacact
     7861 ctgcgggact ttgagtgtca actcagccca gtcttcaaag gttcgaatgc gcatagcgac
     7921 tttcttttct cgcagttcaa aatcaggcgt gtcgatgtag taatttgttt gaagaacagg
     7981 agtgacacct gtgaactggt cttttagacg attgtattca tcttttttca atagtgtttt
     8041 caattcaatt tctaaatgtt tcatttttct tacctttttt tatcgttgaa agcggattta
     8101 tggtataata agcattgtat ttattgtata tgaatctgga gaaaaaatca aagatatttt
     8161 tgacggataa tatgagaaca agggagaata tatgacctta gaatgggaag aatttctaga
     8221 tccttacatt caagctgttg gtgagttaaa gattaaactt cgtggtattc gtaagcaata
     8281 tcgtaagcaa aataagcatt ctccaattga gtttgtgacc ggtcgagtca agccaattga
     8341 gagcatcaaa gaaaaaatgg ctcgtcgtgg cattacttat gcgaccttgg aacacgattt
     8401 gcaggatatt gctggcttac gtgtgatggt tcagtttgta gatgacgtca aggaagtagt
     8461 ggatattttg cacaagcgtc aggatatgcg aatcatacag gagcgagatt acattactca
     8521 tagaaaagca tcaggctatc gttcctatca tgtggtagta gaatatacgg ttgataccat
     8581 caatggagct aagactattt tggcagaaat tcaaattcgt actttggcca tgaatttctg
     8641 ggcaacgata gaacattctc tcaactacaa gtaccaaggg gatttcccag atgagattaa
     8701 gaagcgactg gaaattacag ctagaatcgc ccatcagttg gatgaagaaa tgggtgaaat
     8761 tcgtgatgat atccaagaag cccaggcact ttttgatcct ttgagtagaa aattaaatga
     8821 cggtgtagga aacagtgacg atacagatga agaatacagg taaacgaatt gatctgatag
     8881 ccaatagaaa accgcagagt caaagggttt tgtatgaatt gcgagatcgt ttgaagagaa
     8941 atcagtttat actcaatgat accaatccgg atattgtcat ttccattggc ggggatggta
     9001 tgctcttgtc ggcctttcat aagtacgaaa atcagcttga caaggtccgc tttatcggtc
     9061 ttcatactgg acatttgggc ttctatacag attatcgtga ttttgagttg gacaagctag
     9121 tgactaattt gcagctagat actggggcaa gggtttctta ccctgttctg aatgtgaagg
     9181 tctttcttga aaatggtgaa gttaagattt tcagagcact caacgaagcc agcatccgca
     9241 ggtctgatcg aaccatggtg gcagatattg taataaatgg tgttcccttt gaacgttttc
     9301 gtggagacgg gctaacagtt tcgacaccga ctggtagtac tgcctataac aagtctcttg
     9361 gcggtgctgt tttacaccct accattgaag ctttgcaatt aacggaaatt gccagcctta
     9421 ataatcgtgt ttatcgaaca ctgggctctt ccattattgt gcctaagaag gataagattg
     9481 aacttattcc aacaagaaac gattatcata ctatttcggt tgacaatagc gtttattctt
     9541 tccgtaatat tgagcgtatt gagtatcaaa tcgaccatca taagattcac tttgtcgcga
     9601 ctcctagcca taccagtttc tggaaccgtg ttaaggatgc ctttatcggt gaggtggatg
     9661 aatgaggttt gaatttatcg cagatgaaca tgtcaaggtt aagacctttt taaaaaagca
     9721 cgaggtttct aagggattgc tggccaagat taagtttcga ggtggagcta ttctggtcaa
     9781 taatcaaccg caaaatgcaa cgtatctatt ggacgttgga gactacgtta ccatttacat
     9841 tcccgctgag gaaggctttg aaaccttgga ggctattgag catccattag atattctcta
     9901 tgaggatgac cactttctag tcttgaataa accctatgga gtggcttcta ttcctagtgt
     9961 caatcactct aataccattg ccaattttat caagggttac tatgtcaagc aaaattatga
    10021 aaatcagcag gttcacattg ttaccagact agatagggac acttctggct tgatgctctt
    10081 tgccaagcac ggttatgccc atgcacgatt agacaagcag ttgcagaaga aatctatcga
    10141 gaaacgctac tttgctttgg ttaagggaga tggacatttg gagccagaag gggaaattat
    10201 tgctccgatt gcgcgtgatg aagattccat tattaccaga cgagtggcta aaggcggaaa
    10261 gtatgcccat acttcataca agattgtagc ttcttatgga aatattcact tggtctatat
    10321 tcacctgcac actggtcgaa cccatcaaat ccgagtccat ttttctcata tcggttttcc
    10381 tttgctggga gatgatttgt atggtggtag tctggaagat ggtattcaac gtcaggctct
    10441 gcattgccat tacctatcct tttatcatcc atttttagag caagacttgc agttagaaag
    10501 tcccttgccg gatgatttca gtaaccttat tacccagtta tcaactaata ctctataaaa
    10561 actgtctcag agtataatta ttatcttaaa ggagaaaact catggaagtt tttgaaagtc
    10621 tcaaagccaa ccttgttggt aaaaatgctc gtatcgttct ccctgaaggg gaagagcctc
    10681 gtattcttca agcaacaaaa cgcttagtaa aagaaacaga agtgattcct gttttgcttg
    10741 gaaatcctga aaaaattaaa atttatcttg aaattgaagg aatcatggat ggttatgagg
    10801 tcatcgaccc tcaacattat cctcaatttg aagaaatggt ttctgccttg gtggagcgtc
    10861 gcaagggcaa aatgactgaa gaagatgtac gcaaggtttt ggttgaagat gtcaactact
    10921 ttggtgtgat gttggtttac ttgggcttgg ttgatggaat ggtgtcagga gcgattcact
    10981 caacagcttc aacagttcgc ccagctctac aaatcatcaa aactcgtcca aatgtaactc
    11041 gtacttcagg agccttcctc atggttcgtg gtacggaacg ttacctattt ggagactgtg
    11101 ccattaatat caatccagat gcagaagcct tggctgaaat tgccatcaac tcagcaatca
    11161 cagctaagat gtttggcatc gaacctaaaa ttgccatgtt gagctattct actaaaggtt
    11221 cagggtttgg tgaaagcgtt gataaggtcg ttgaagcaac taaaattgct cacgacttgc
    11281 gtcctgacct tgaaatcgat ggtgagttgc aatttgatgc ggcctttgtt cccgaaactg
    11341 cagctctgaa agctccggga agtacagtag ctggtcaagc aaatgtcttc atcttcccag
    11401 gtatcgaggc aggaaatatc ggttacaaga tggctgaacg cctgggtggc tttgcggctg
    11461 taggacctgt tttgcaaggt ttaaacaagc cagttaatga tctttctcgt ggatgtaatg
    11521 cagatgatgt ttacaagttg accctcatca cagcagctca agcagttcat caatagtgaa
    11581 aactataaag tgatatacta tgctatactg tagttatgaa actatgtacg aaaagcactg
    11641 ccattaattc ctgagaacta aattactgat tggtgtcaaa aaggaaaact tccaagcgat
    11701 gatatcctgt ctatacacga cctatagaaa tctgtaatat acatatccgt aaaacgataa
    11761 attccctttt tgattttaaa tgagtatgaa aagagaattt tttggctctt tgtcaactgt
    11821 agtgggttga agaaaagcta agctcgagaa aggacaaatt tcatcctttc ttttttgata
    11881 ttcagagcga taaaaatccg ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg
    11941 cgcttgataa gtttgatgag attattggtc gcttccagtt tggcgttaga atagtgtagt
    12001 tgaagggcgt tgataatctt ttctttatct ttgaggaagg ttttaaagac agtctgaaaa
    12061 ataggatgaa cctgcttaag attgtcctca ataagtccga aaaatttctc tggttcctta
    12121 ttctggaagt gaaaaagcaa gagttgatag agctgatagt ggtgtttcaa gtcttccgaa
    12181 tagctcaaaa gcttgtttaa aatctcttta ttggttaagt gcatacgaaa aataggacga
    12241 taaaatcgct tatcactcag tttacggcta tcctgttgaa tgagtttcca gtagcgcttg
    12301 atagccttgt attcatggga ttttcgatga aactgattca tgatttggac acgcacacga
    12361 ctcatagcac ggctaagatg ttgtacaatg tgaaagcgat caagaacgat tttagcattc
    12421 gggagtgaaa cagcctggga gactgtttca gcctgagcct agaaatttga aagcgaagct
    12481 gtttagccaa gtcatagtaa gggctaaaca tatccatagt aatgattttg acgcgacatc
    12541 ggacggctct atcatattta agaaagtgat ctcggatgac agcttgtgtt ctaccttcaa
    12601 gaacagtgat gatattgaga ttgttaaaat cttgcgcaat aaagctcatc tccatctccc
    12661 gattgaaaca gtcactcccc ggactgtttc aacgtcccaa gacataatct taggcagatt
    12721 tctaaaatta cactcaaagt ggaagtcatt gagctttcga atgacagttg aagttgagat
    12781 ggaaagctga tgggcaatat cagtcataga aatcttttca attaactttt gagcaatctt
    12841 ttggttgatg atacgaggga tttgatgatt cttcttgacg atagaagttt cagcaaccat
    12901 aattttagaa caatgatagc acttgaaacg acgctttcta aggagaattc tagtaggcat
    12961 accagttgtt tcaagataag gaattttaga aggtttttga aagtaatatt tcttcatttg
    13021 acttccgcac tcaggacaag atggagcttc atagtccagt ttggcgatga tttccttgtg
    13081 tgtatcctta ttgacgatgt ctaaaatctg gatattaggg tctttaatgt ctagtaattt
    13141 tgtgataaaa tgtaattgtt ccatatgatt ctttctaatg agttgttttg tcgcttttca
    13201 ttataggtca tatgggactt ttttctacac aaaaataggc tccataatat ccatagggga
    13261 tttacccact acaaatatta tagagtcatt tttgcacctt tcttagcctt tgttatcgac
    13321 aagcattgtt ctagctcctt gtttttagaa aggtaatttc ccagcgaaag cacccagttt
    13381 tttcttggta gtttcatcga tttgttcaag agcagagttg atggcttgaa cggtcatatc
    13441 agaaagagtc tcaaggtcct ctgggtcaac gacagctgga ttgaaatcaa tgctgacaac
    13501 tttcttatcg ccagttaagg tcgcttggac aagatcttga gcagatttgc caacaaattg
    13561 catagcagca agttcagctt ggctttgttc catttgtttt tgaagttttt gtgcttgacg
    13621 catcatgttt tgcatgttca tcataagatt tctaaagttc ctttcatctc aaggggataa
    13681 tccttgttgt taacaagtgc ctgattttct ctcctaattg ttattagtag catagccatc
    13741 aagcccaagt attgatttta ttataccatt tttttaagac atagtctttt attggtgaga
    13801 gttatttatg tcaaggagtg attagaaata aattaaaata atgatttttg ctaagagggc
    13861 tctattctag tttcatggaa atgattttac taaaggttcg tatgctttgt ttgcaaacat
    13921 gttacatcta tctatttttg gataaatagt tgtctattat tatttttatg ctaatagtaa
    13981 aatctaaatg gtagcctacg attttttaga aagaaaatgg tacaatattt ctaagagaaa
    14041 atacaatggg aggtaaaatg aggttattac ctataagaaa aatatcacgt cagtctaaaa
    14101 ggttagcact ttttttgacg ttttgtgctg gatatgtgga tgcttacact tttattgttc
    14161 gcgggaatac ccttgtagct ggacaaactg gaaatgttgt ctttctttca gtagaattaa
    14221 ttaaaaataa tgtttcggat gttagggaca aggttctcac cttgctagcg tttatgatgg
    14281 gagtcttttt attaacgatt tataaggaaa aattgagaat tgtgaaaaaa cctattctgt
    14341 ccttgattcc cttggcaatc ttatcaatca ttattgcttt tgtgccgcaa actgtggata
    14401 atatctatct agtgccgccc ttggccttct gtatgggact ggtgacaact gcttttggag
    14461 aagtatcggg tattgcctat aataacgctt ttatgacagg gaatatcaaa cggaccatgc
    14521 tggcttttgg agattatttc cgaaccaagc acactccttt tttgcgtgaa ggattcatat
    14581 ttgttagcct gcttagtagt tttgtccttg gcgttgtctt ttcagcctat ttgacgattt
    14641 tctatcatga aaagaccatt cttggtgttc ctattatgat gagcgttttt tacctcagca
    14701 tgctttttgc ctcttggcag aaaaaagtaa aagaaaaagc ttcattttag gtgttattac
    14761 ttgtaagaaa ataggagata tgctatactt gaagagttga ctatgcacga tcctgtgcaa
    14821 ccgcacgaac atcgttgctt gattattcaa gtttaagtgg ttcgtcccac gatgctaggc
    14881 gagtcttcac aaaaaatcgg ggaaacccat aaaaatcata ggaggtgcat aatgagcaca
    14941 tacgcaatta tcaaaactgg cggaaaacaa gttaaagttg aagttggtca agcagtttac
    15001 gttgaaaaat tgaacgttga agctggtcaa gaagttactt ttaacgaagt tgttcttgtt
    15061 ggtggtgaaa acactgttgt cggaactcca cttgttgctg gagctactgt agttggaact
    15121 gttgaaaaac aaggaaaaca aaagaaagtg gttacttaca agtacaaacc taaaaaaggt
    15181 agccaccgta aacaaggtca ccgtcaacca tatacaaaag ttgtcatcaa cgcaatcaac
    15241 gcttaatttt aaggagaaca catgatacag gcagtctttg agagagccga agatggcgag
    15301 ctgaggagtg cggaaattac tggacacgcc gagagtggcg aatacggctt agatgtcgtg
    15361 tgtgcatcgg tttctacgct tgccattaac tttatcaatt ctattgagaa atttgcaggc
    15421 tatgaaccaa tcctagaatt aaacgaagat gaaggtggct atctgatggt tgaaatacca
    15481 aaagatcttc cttcacacca gagagaaatg acccagttat tctttgaatc atttttctta
    15541 ggtatggcaa acttatcgga gaactattct gagttcgtcc aaaccagagt tatcacagaa
    15601 aactaacacg gaggaaaaca ttatgttaaa aatgactctt aacaacttgc aacttttcgc
    15661 ccacaaaaaa ggtggaggtt ctacatcaaa cggacgtgat tcacaagcaa aacgtcttgg
    15721 agctaaagca gctgacggac aaactgtaac aggtggatca atcctttacc gtcaacgtgg
    15781 tacacacatc tatccaggtg taaacgttgg tcgtggtgga gacgatactt tgttcgctaa
    15841 agttgaaggc gtagtacgct ttgaacgtaa aggacgcgat aaaaaacaag tttctgttta
    15901 cccaatcgct aaataaaaag gtccattgaa ccttttatcc cgaaccttga aatgtaaagg
    15961 tgaggaagct agaaacagct taaaataagg ctttccgagt tttcggagag cctgtttttt
    16021 tgttttggta cccatacttt ttaatatgta tagtggattg atactcttcg aaaatcaaat
    16081 tcaaaccatg tcaatttcac cttgccgtac tcaagtacag cctgcggcta acttcctagt
    16141 ttgcacttta attttcattg agtatgaatc tggaatagaa cactgttaaa cattgatatg
    16201 agtttcctac tcgatttctt cagattttat ttcaattgac tataagaact gctatctggt
    16261 ttcaaatatt ggcttgtcgt cccttcactt gtctgaatgg cttgagccgt tccttctgat
    16321 aagggaaaag atattcttta gctgaaacgg tctgagaatc caagctaaca gatggagaga
    16381 aaaatagccc agtctgaagc acactagatg ggagttgttg gaaagcagtc atctagtttt
    16441 tctttgctgt tttggctttt ttctttgtca ttagggaaag tgacttgctt caaatcaggg
    16501 agtttaggaa attcttcaaa catcttgccc aagttgtctc attttgtaaa ttttacagcc
    16561 ataggtgtac ctcgattcta aattctacct tttcggcacc aattagtaat ttaaagttct
    16621 caggagttag ttgcattgct ttttcataca taagcatagt atgacacttt atggttaccg
    16681 aacaagtcta atcactcctt gcaaaatttt gaagatgtcc tacaagtttt tgagaagaat
    16741 attgcaaagt tcatagttaa gcaacgatag aataaagtgc tttttgaaaa caggtacact
    16801 tcatgtgaaa aaaacaacat ttcagatttt ctgttccaga aatagctatc gctatgatat
    16861 aattatttta tgattattac tattcctata aaaaaccaaa aagatattgg cacaccatct
    16921 gattcagtcg ttgttctcgg ctattttgat ggcatacata aggggcatca agaattattt
    16981 cgtgttgcca acaaggctgc gagaaaggat ttgttgccta tcgtcgttat gacctttaat
    17041 gaatctccaa agatcgcttt agagccttat catccagatt tgtttttgca tattttgaac
    17101 cctgctgaac gtgaaagaaa attaaagcgc gaaggtgtag aagaattata tctccttgat
    17161 tttagtagtc aattcgctag tctcactgca caagaattct ttgcaactta tatcaaggct
    17221 atgaatgcca aaattattgt tgcaggtttt gattatacat ttggttctga caaaaaaaca
    17281 gcagaagatt taaaggatta ctttgatgga gaagttatca ttgttccacc tgtagaagat
    17341 gagaaaggaa agattagttc aactcgtatc cgtcaagcta ttttagatgg aaatgtgaaa
    17401 gaagcaggaa aacttttggg ggcaccgctt ccatcaagag gtatggtggt tcatggtaat
    17461 gctcgtggtc gtacaattgg ttatccgaca gcgaatttag tgcttttaga ccgtacttat
    17521 atgccagcag atggcgttta tgttgttgat gttgagattc aaagacagaa gtatcgtgct
    17581 atggctagtg tcgggaaaaa tgtgaccttt gatggagaag aagcacgttt tgaagtcaat
    17641 atttttgatt ttaatcaaga tatttatggg gaaaccgtca tggtttattg gcttgatcgc
    17701 attcgagata tgaccaaatt tgactcagtt gaccaattag tggatcagtt aaaggctgat
    17761 gaagaagtaa ctcggaattg gtcttaagag cttgagtaaa taaaataaaa aagaggttgt
    17821 ctgtaaccca aaagatagat gatttagtct aacttttgag gtcacgacat tacctctttt
    17881 tattcttttt caaaggtgaa gccttctcct aggatttcat gggcttctgt aatagttata
    17941 aaggcttgag gatcgattcg atgaatcatt tccttcgttt tcacaatttc atttcttccg
    18001 acaatacagt agatgatttt caaattttct ttactatagt agccttgacc agaaataaaa
    18061 gtaacacctc ttccgaggtc atcattaatc gccttagcaa gttggtcagg acgttttgtg
    18121 ataatcataa agcctttgcc ggcatatcct ccttcaccaa tcaaatcaat aacacgagaa
    18181 acaataaaat caaacaaaag cgtgtaggaa accaatctca aatccttgaa gattaggaga
    18241 atcaacatga gaatacaaaa atctaagata aagagcagtt ttcctatgga tatatgagtg
    18301 tatttgttga gaatacgagc tagaatatca gttccgccag ttgtacctcc agcattaaaa
    18361 ataattccaa ggccaattcc caataggatt cccgctataa gggctgtgat tagtaaatca
    18421 ccttgaagat caatatgaag gggaatatgc tcaaaaaaag ctaaccagcc ggacaaagct
    18481 aaggttccta gtaaactaga atagagggat ttggctccaa aaatcttcca agctaggatg
    18541 aaaaggggaa tattaatcag caggttcatg agggaaacag ggattttaaa aagataaaag
    18601 gtgatgaggg taatgcctgt cgcccctcct tcaaagagat gatggggaac tacaaaataa
    18661 gtcagtccaa aagcataaat agcagcacct agtaaaatgg taaaaatggg gtaaattttt
    18721 ttaatcatag gacacctctt ttcttataag ttgattatat caaattttac ggaaaatttg
    18781 att
//
LOCUS       DAVKXA010000042        18778 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKXA010000042 DAVKXA010000000
VERSION     DAVKXA010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.042"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1..755
                     /locus_tag="VW883_001581"
                     /pseudo
     CDS             1..755
                     /locus_tag="VW883_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(819..1901)
                     /locus_tag="VW883_001582"
     CDS             complement(819..1901)
                     /locus_tag="VW883_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0274692.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1898..2875)
                     /locus_tag="VW883_001583"
     CDS             complement(1898..2875)
                     /locus_tag="VW883_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0274693.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            3090..3486
                     /locus_tag="VW883_001584"
                     /pseudo
     CDS             3090..3486
                     /locus_tag="VW883_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            3721..5112
                     /locus_tag="VW883_001585"
     CDS             3721..5112
                     /locus_tag="VW883_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0274694.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5226..6068
                     /locus_tag="VW883_001586"
     CDS             5226..6068
                     /locus_tag="VW883_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0274695.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            6341..7102
                     /locus_tag="VW883_001587"
     CDS             6341..7102
                     /locus_tag="VW883_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0274696.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            7296..8213
                     /gene="glyQ"
                     /locus_tag="VW883_001588"
     CDS             7296..8213
                     /gene="glyQ"
                     /locus_tag="VW883_001588"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0274697.1"
                     /translation="MSKKLTFQEIILTLQRFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            8425..10461
                     /locus_tag="VW883_001589"
     CDS             8425..10461
                     /locus_tag="VW883_001589"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0274698.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            10503..10760
                     /locus_tag="VW883_001590"
     CDS             10503..10760
                     /locus_tag="VW883_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0274699.1"
                     /translation="MDPKKIARINELAKKKKTEGLTLEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10877..12121)
                     /locus_tag="VW883_001591"
     CDS             complement(10877..12121)
                     /locus_tag="VW883_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0274700.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGDHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12139..12744)
                     /locus_tag="VW883_001592"
     CDS             complement(12139..12744)
                     /locus_tag="VW883_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0274701.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQSFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEEFDWENL"
     gene            complement(12804..13727)
                     /locus_tag="VW883_001593"
     CDS             complement(12804..13727)
                     /locus_tag="VW883_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0274702.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHDIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14022..15401
                     /locus_tag="VW883_001594"
     CDS             14022..15401
                     /locus_tag="VW883_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0274703.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVIAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            15553..16428
                     /gene="pdxS"
                     /locus_tag="VW883_001595"
     CDS             15553..16428
                     /gene="pdxS"
                     /locus_tag="VW883_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0274704.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            16429..17013
                     /gene="pdxT"
                     /locus_tag="VW883_001596"
     CDS             16429..17013
                     /gene="pdxT"
                     /locus_tag="VW883_001596"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0274705.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
     gene            17570..18301
                     /locus_tag="VW883_001597"
     CDS             17570..18301
                     /locus_tag="VW883_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274706.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            18319..>18778
                     /locus_tag="VW883_001598"
     CDS             18319..>18778
                     /locus_tag="VW883_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HEV0274707.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVGTSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLS"
BASE COUNT         5761 a         3357 c         4071 g         5589 t
ORIGIN      
        1 catttgaagg ctacagaggc aggagaattt gttacaatac cttatttcag gcttatatcg
       61 ttcctacaca cgtgatgcct tctatcaact gttgaagcgc catggttggc gaaatattat
      121 gccacgtcca gaacatccta agaaagcaga cgctcaaacc attgtcgcgt ctaaaaataa
      181 aatctcaatt caagaagaaa agaaagcgct ttaaaaccag tagacgtttt cataaggttc
      241 gctcgatgta ccaagatgag gctggtttcg gtagaatcag taaactggga tcttgttggt
      301 ctccaatagg agtaggtcca catgtccata gtcactatat acgagaattt cgctattgtt
      361 atggagctgt tgatgcccat acaggcgaat catttttctt aagagctggt ggatgtaata
      421 ctgagtggat gaacgccttt ttagaagagc tttcacaagc ttatccagat gattatcttt
      481 tactcgttat ggacaatgct atatggcata aatcaagtac cttaaaaatt ccgactaata
      541 ttggctttgc atttattcct ccatacacac cagagataaa ccccgttgaa caagtgtgga
      601 aagagattcg taaacgtgga tttaagaata aagcctttcg aactttggaa gatgtcatga
      661 atcaacttca agatattata caagaactgg agaaggaggt gataaagtcc atcgttaatc
      721 ggagatggat tagaatgctt tttgaaaaca gatgagtata aaattgaatt gcttgtaaaa
      781 aagctccata cactggatgt gtatagagca atggggcttt atttgatata gagttcttgg
      841 ttttttagga caatttctcg gatacttgca aactttttaa gttttttgat ttcttctgga
      901 tgagtgacga gagtaataac atatccttcc ttgcccatac ggccagtacg gccagcacgg
      961 tgtgtgtagg tttcgctatc tctaggaata tcaaagttta cgacacattc taggctatcg
     1021 atatcaattc cacgagccaa aaggtcagtt gcaagaagca gggttagttg gttatcttta
     1081 aacttttcta agatgacttt tctaaattta acattaacat cactagcgag ggaaacagcc
     1141 aatatatcac gatactgtag tttttcctcg gcattcccaa ggtctgacag gctattgaag
     1201 aagactagac cacggaaatc ctctacatga gccagttttc gtagtatatc cactcgatga
     1261 cgttggtcta cctgcatgta gaaatgctgg atattgtcca atttttgatc agagagatca
     1321 atagtgcgtg tattcggtac aatcttttct tgatcaaact tggtcgtggc actcatgtag
     1381 accagttggt ggtcacgagg tgcgtagtga gtgatttttt ctacaaagtg aatctgagaa
     1441 tcatctagta attggtcaaa ttcatccagg atgatggttt ccacattcat catcttgatt
     1501 tttttaagtt taatgagttc aaagatacgg ccaggagttc caatcagaat ttctggcccc
     1561 tttttaagac gttcaatttg tcgtttctga cttgaacctg aaaggaagag ttgagcagtc
     1621 aatccgatag cttctgccca cgttttacat acatcaaaaa tctgtccagc aagttccgta
     1681 tttggtgcta gaatcaagag ttgttgggct tttttctttt gtagtctgag aagacttggt
     1741 aggagataag ctagggtctt accagttccg gtttggctca ctcctaggag gttttctcca
     1801 gcaagaaggg gctcaaatag ttgagtttga atgggggtga attcttggaa accgagttgg
     1861 tcactcagtt cttgccattc agtcggtagt ttggttttca tttttctgcc tcaaatctaa
     1921 tgccagcagt ctggcgcatg gtatatagta gctcatgaac agagcctgca tcatacagcc
     1981 aagtttggta gagattcaga tctggttgct ggatcatgtg tgcaaatgca gcgacttcct
     2041 cagtcatcgt atgaggagcc tgttggatag gaagctggac ttgatttcct tggtggtcgg
     2101 taaaaatagc tgaacgaata tgctcaatcg tgttgagagt caaggttcca tctgttgtat
     2161 aaatctcgca aggaagattg gaagtgatgt tttttccagc cttgatgtga acttgatagt
     2221 ctgggtagaa gaggatacca tctccattta ggtcaatgct attgtcaagc tgttgagcat
     2281 ggtaagtcgc gtcattagct ttttcaaaaa gacgaacagc agcatagagg ggataaatcc
     2341 ccaaatccat gagggctcca ccagcaaaac ggtctgaaaa gacatttggt gtttgtccag
     2401 ccaacaagtc aggcatcttg gaagagtatt tggcatagtt gaaatctgct cctaacactt
     2461 gcttatctgc taaaaagttt ttgatagtag taaaggcttt ctcgtggtaa ttacgagctg
     2521 cttcaaagat aaaacagtta tttttttcag ctgtttgaat caaatcaaac cattcttgtg
     2581 gttgagtgac agctggcttt tcgagaataa catgtttacc agcagacaag gcagcttttg
     2641 cctgagcaaa atgtaaggag tttggactgg cgatatagac taaatcaaaa gaagatttga
     2701 agaagacttc taattgatcg aatagttgga tattctgata gcgagaagca aaggttgctg
     2761 cagtttctag ttttctagaa tagattgcga ccagttggta ttctccactg gtatgggctg
     2821 cttctatgaa atgatggctg atagcgccag ttccgatgac acctaatttt agcataaata
     2881 ctccttttcc gattttaaat ccttctttca ttataacata gatagacggg actatccaac
     2941 agagaggaga aaatttcaaa taagctatta gctttctttt ccgaataaat agatagaagc
     3001 atagaatcta gcaaacctag atttaaaaat gtgctataat agaaggagga aaaggaggat
     3061 tctcagacat ccaggtatca gcccaactaa tgatttgtca atttatccgc gatatgctgg
     3121 acttgccagc aaaaaatgtg acgattttgg agggaagtaa cattcacgtc ttgccttcca
     3181 tgccctactc agcgcaagat ttctatacta gtatagacgt cttggcggag ttagataatg
     3241 gaatccaagt tatcatcgaa attcaggttc atcatcgaaa ttcaggttca tcatcagaat
     3301 tttttcatca atcgcctatg ggcttatctg tgcagtcagg ttaatcaaaa cctagaaaaa
     3361 attcgccaac gtgaaggtga tacccaccag agctacaaac aaatcgcacc agtatacgct
     3421 atcgcaattg tcgatagtaa ttacttctca gatgacctag cttttcatag ttttatagta
     3481 aaatgaaatg agaacaggac aaatcgatca ggacagtcaa atcgatttct aacaatgttt
     3541 tagaagtata ggtctactat tctagcttca atctactaga aattccatag atagaaaact
     3601 acataatctc tacagatacg gatgttggag ttgatgtaag atgctttggc ttgctagagg
     3661 aattgtggat tgccaaattg tatcattgaa attattgctc aaatttgtta tgatataaat
     3721 atgaataaaa gtagactagg acgtggcaga cacgggaaaa cgagacatgt attattggct
     3781 ttgattggta ttttagcaat ttctatttgc ctattaggcg gatttattgc ttttaagatc
     3841 taccagcaaa aaagttttga gcaaaagatt gaatcgctca aaaaagagaa agatgatcaa
     3901 ttgagtgagg gaaatcagaa ggagcatttt cgtcaggggc aagccgaagt gattgcctat
     3961 tatcctctcc aaggggagaa agtgatttcc tctgttaggg agctgataaa tcaagatgtt
     4021 aaggacaagc tagaaagtaa ggacaatctt gttttctact atacagagca agaagagtca
     4081 ggtttaaagg gagtcgttaa tcgtaatgtg accaaacaaa tctatgattt agttgctttt
     4141 aagattgaag agactgaaaa gaccagtcta ggaaaggttc acttaacaga agatgggcaa
     4201 ccttttacac ttgaccaact gttttcagat gctagtaagg ctaaggaaca gctgataaaa
     4261 gagttgacct ccttcataga ggataaaaaa atagagcaag accagagtga gcagattgta
     4321 aaaaacttct ctgaccaaga cttgtctgca tggaattttg attacaagga tagtcagatt
     4381 atcctttatc caagtcctgt ggttgaaaat ttagaagaga tagccttgcc agtatctgct
     4441 ttctttgatg ttatccaatc ttcgtactta ctcgaaaaag atgcggcctt gtaccaatct
     4501 tactttgata agaaatatca aaaagttgtc gctctaacct ttgatgatgg tccaaatcca
     4561 gcaacgaccc cgcaggtatt agagacccta gctaaatatg atattaaagc gactttcttt
     4621 gtgcttggga aaaatgtttc tgggaatgag gacttggtga agaggataaa atctgaaggt
     4681 catgttgttg gaaaccatag ttggagccat ccgattctct cgcaactctc tcttgatgaa
     4741 gctaaaaagc agattactga tactgaggat gtgctaacta aagtgctggg ttctagttct
     4801 aaactcatgc gtccacctta tggtgctatt acagatgata ttcgcaatag cttggatttg
     4861 agctttatca tgtgggatgt ggatagtctg gactggaaga gtaaaaatga agcatctatt
     4921 ttgacagaaa ttcagcatca agtagctaac ggctctatcg ttttgatgca tgatattcac
     4981 agtccgacag tcaatgcctt gccaagggtc attgagtatt tgaaaaatca aggttatacc
     5041 tttgtgacca taccagagat gctcaatact cgcctaaaag ctcatgagct gtactatagt
     5101 cgtgatgaat aagcaagaaa aaataggtct gttagatatt tgacagactt attttttaca
     5161 gaagatagta ctacttaaaa aatgttttat gctataattg atgaataaaa tagaaggaga
     5221 agcatatgaa tacctatcaa ttaaataatg gagtagaaat tccagtattg ggatttggaa
     5281 cttttaaggc taaggatgga gaagaagcct atcgtgcagt gttagaagcc ttgaaggctg
     5341 gttatcgtca tattgatacg gcggcgattt atcagaatga agaaagtgtt ggtcaagcaa
     5401 tcaaagatag cggagttcca cgtgaagaaa tgttcgtaac taccaagctt tggaatagtc
     5461 agcaaaccta tgagcaaact cgtcaagctt tggaaaaatc tatagaaaaa ctgggcttgg
     5521 attatttgga tttgtatttg attcattggc cgaacccaaa accgctcaga gaaaatgacg
     5581 catggaaaac tcgcaatgcg gaagtttgga gagcgatgga agacctctat caagaaggga
     5641 aaatccgtgc tatcggcgtt agcaattttc ttccccatca tttggatgcc ttgcttgaaa
     5701 ctgcaactat cgttcctgcg gtcaatcaag ttcgcttggc gccaggtgtg tatcaagatc
     5761 aagtcgtagc ttactgtcgt gaaaagggaa ttttattgga agcttggggg ccttttggtc
     5821 agggagaact atttgatagc aagcaagtgc aagaaatcgc agcaaatcac ggaaaatcga
     5881 ttgctcagat agccttggcc tggagcttgg cagaaggatt tttaccactt ccaaaatctg
     5941 tcacaacctc tcgtattcaa gctaatcttg attgctttgg aattgaactg agtcatgagg
     6001 agagagaaaa cttaaaaacg attgctgttc aatcgggtgc tccacgagtt gatgatgtgg
     6061 atttctagaa aatcataaaa agaattgtac attattctaa tttttgatat aatagtcagc
     6121 aggaaagaaa gtcttatggc gttcttcaag cgagcttggg atagtgggag ccaagtaggg
     6181 caaaataaag ggctggcgct ttctgtagta ttttcaaaaa caatgaagta ataaattagg
     6241 gtggaaccgc gtttctgacg cccctaggtt aaatcaacct aggattgtca gatgtggttc
     6301 ttttgcttat tcagtctatt gtgtgaaaga aaggagagcc gtggacaacc tttatcttgt
     6361 aaaagacgat agtcaactag ctacatttcg tgattttgta gtaagaaata ctgaaaagtt
     6421 gaaagattat caatcttttt taaagaatga acttgcagtc tgtgatttac cgcaagccgt
     6481 tatttggtca gattttaatg ctgctacaca gattattagg gaaagcgctg ttccagccta
     6541 tacaaataat agacgaatgg ttatggcgcc tgatttagct gtttggaaag agttgtattt
     6601 gtatcaattg atggactacg agtgttctca gcaaactcaa gcaatagaaa gtcactatca
     6661 ttctttatct gaaaatttcc tcttacagat tgtaggacat gagttagctc attggtcgga
     6721 gcatttttta gatgattttg atggttatga ctcttatatc tggttcgaag aggggatggt
     6781 tgaatatatt agtcgcaagt atttcttgac agaagaagaa tttcaagcgg aaaaaatttg
     6841 taatcaatct ctcgtagaac tttttcagaa gaagtatggt tggcattcat tgaatgattt
     6901 tggttcttcg acttatgata agaactatgc aagtattttt tatgaatact ggcgcagctt
     6961 tttgacagta gataagttgg tagaaaattt aggtagtgta caagcggtct tagattctta
     7021 tcatttatgg gcaaatacag aaaaaacttt tcccttgtta gattggtttg ttcagcagaa
     7081 attaattgaa aaagaaatat aaaaactaaa ggagtaaaca atgtctaaga aattgacatt
     7141 tcactgcatc agtggcagag acctccttac agtcggactg ccccacgctc agcactaggg
     7201 tgctgagcta gacgcagtac taactcgtct tgcctcgtat aatcgacgag gtagactcgt
     7261 gtcgcaagaa attatttttt attaaggagt attcaatgtc taagaaatta acatttcaag
     7321 aaattatttt gactttgcaa cgattttgga atgaccaagg ttgtatgctt atgcaggctt
     7381 atgacaatga aaaaggtgcg ggaacaatga gtccttacac tttccttcgt gctatcggac
     7441 ctgagccatg gaatgcagct tatgtagagc catcacgtcg tcctgctgac ggtcgttatg
     7501 gggaaaaccc taaccgtctc taccaacacc accaattcca ggtggtcatg aagccttctc
     7561 catcaaatat ccaagaactt taccttgagt ctttggaaaa attgggaatc aatcctttgg
     7621 agcacgatat tcgttttgtt gaggacaact gggaaaaccc atcaactggt tcagctggtc
     7681 ttggttggga agtttggctt gacggaatgg aaatcactca gttcacttat ttccaacaag
     7741 tcggtggatt ggcaactagc cctgtgactg cggaagttac ctatggtttg gagcgcttgg
     7801 cttcttacat tcaagaagta gactctgtct atgatatcga gtgggctgat ggtgtaaaat
     7861 acggagaaat ctttatccag cctgagtatg agcactcaaa atattcattt gaaatttcgg
     7921 accaagaaat gttgcttgaa aattttgata agtttgaaaa agaagctggt cgtgcattag
     7981 aagaaggctt ggtacaccct gcctatgact atgttctcaa atgttcacat acctttaatc
     8041 tgcttgacgc gcgtggtgcc gtatctgtaa cagagcgtgc aggctatatc gctcgtatcc
     8101 gtaacttggc ccgtgtcgta gccaaaacct ttgtcgcaga acgcaaacgc ctaggctacc
     8161 cacttttgga tgaagaaaca agagctaaac tcctagcaga agacgcagaa taaagagagt
     8221 gacaaattac gaaaatgggc gaacagagtg agccctgagc cagttgccgc agtgatgaag
     8281 gtatccttag tgaaactaag gatactaggc aaaattggag acttttggct ccaattttag
     8341 caatgaaaca acgaagttgg ttgcttgcgt gccaatcaca taaggcaaac tggaaaataa
     8401 aaagatactt ttcggagaaa aaacatgaca aaaaacttat tagtagaact cggtcttgaa
     8461 gaattaccag cctatgttgt cacaccaagt gaaaaacaac taggcgaaaa aatggcagcc
     8521 ttcctcaagg aaaaccgcct gtcttttgaa gccattcaaa ccttctcaac accacgtcgt
     8581 ttggctgttc gtgtgactgg tttatcagac aaacagtctg atttgacaga agatttcaag
     8641 ggaccagcaa agaaaattgc cttggatagt gatggaaact tcaccaaagc agctcaagga
     8701 tttgtccgtg ggaaaggttt gactgttgaa gatatcgaat tccgtgaaat taagggtgaa
     8761 gaatatgtct atgtcactaa ggaagaagtt ggccaatcag ttgaagccat tgttcctggt
     8821 gttgtagatg tcttgaagtc attgactttc cctgtcagca tgcactgggc tggaaatagc
     8881 tttgaataca tccgccctgt tcacacttta actgttctct tggatgagca agagtttgac
     8941 ttggatttcc ttgatatcaa gggaagtcgt gtgagccgtg gccatcgttt cttggggaaa
     9001 gaaaccaaaa ttcagtcagc attgagctat gaagaagacc ttcgtaagca gtttgtaatc
     9061 gcagatccat gtgaacgtga gcaaatgatt gttgaccaaa tcaaggaaat tgaggcaaaa
     9121 catggtgtac gtatcgaaat tgatgcggat ttgctgaatg aagtcttgaa tttggttgaa
     9181 tacccaactg ccttcatggg aagttttgat gctaaatacc ttgaagttcc agaagaagtc
     9241 ttggtgactt ctatgaagga acaccagcgt tactttgttg ttcgtgatca agatggaaaa
     9301 ctcttgccaa acttcatttc tgttcgtaac ggaaacgcag agcgtttgaa aaatgtcatc
     9361 aaaggaaatg aaaaagtctt ggtagcccgc ttggaagacg gagaattctt ctggcgtgaa
     9421 gaccaaaaat tggtgatttc agatcttgtt gaaaaattaa acaatgtcac cttccatgag
     9481 aagattggtt cccttcgtga acacatgatt cgtacgggtc aaatcactgt acttttggca
     9541 gaaaaagctg gtttgtcagt ggatgaaaca gttgaccttg ctcgtgcagc agccatttac
     9601 aagtttgact tgttgacagg tatggttggt gaatttgacg aactccaagg aattatgggt
     9661 gaaaaataca cccttcttgc tggtgaaact ccagcggtgg cagctgctat tcgtgaacac
     9721 tacatgccta catcagctga aggagaactt ccagagagca aggtcggcgc agttctagcc
     9781 attgcagaca aattggatac gattttgagt ttcttctcag taggattgat tccatcaggt
     9841 tctaatgacc cttatgccct tcgtcgtgca actcaaggtg tggttcgtat cttggatgcc
     9901 tttggttggc acattgctat ggatgagctg attgatagcc tttatgcatt gaaatttgac
     9961 agtttgactt atgaaaataa agcagaggtt atggacttta tcaaggctcg tgttgataag
    10021 atgatgggct ctactccaaa agatatcaag gaagcagttc ttgcaggttc aaactttgtt
    10081 gtggcagata tgttggaagc agcaagtgct ctcgtagaag taagcaagga agaagatttt
    10141 aaaccatctg ttgaatcact ttctcgtgcc tttaacctgg ctgagaaggc agaaggggtt
    10201 gctacagttg attcagaact atttgagaat gaccaagaaa aagctttggc agaagcagta
    10261 gaaacactcg ttttatcagg acctgcaagt cagcaattga aacaactctt tgcgcttagc
    10321 ccagtcattg atgctttctt tgaaaatact atggtaatgg ctgaagatca ggctgtccgt
    10381 caaaatcgtt tggcaatctt gtcacaacta accaagaaag cagctaagtt tgcttgtttt
    10441 aaccaaatta acactaaata aaatttgata aacggacttt atcttattac agaggagaag
    10501 aaatggatcc gaaaaaaatt gctcgtatca atgagcttgc taaaaagaaa aaaacagaag
    10561 gcttaacact agaagaaaaa gtggaacaag ccaaactacg tgaggagtac atcgaaggtt
    10621 atcgtcgcgc tgttcgtcat cacattgaag gaatcaaaat tgtggacgaa gaaggaaacg
    10681 atgttacacc agaaaaacta cgccaagtac aacgtgaaaa aggattacat ggccgtagtc
    10741 ttgatgaccc aaattcataa tatgtactct tttttttaac aaagatagat gaaacgataa
    10801 caaagagact agcagtttgt gtttgctagt cttttttcgc taaaaaagga accataatgg
    10861 ttcctaaaaa ctatcattag taacttgcac cggctgtagc gtctgcgtca ccaccgtggc
    10921 ctccagcatc ccctgaatca gaagcgccag aagtagcatc ggcgtctcca tgatctccgg
    10981 cagcaggagc aaatggtccg ctaccaccca ccaaacgttg accagtctct tttaggtacc
    11041 agtcaagcca tggttggaag ttaaagacaa tttcattgat accagcgtat gatccatcag
    11101 gatagtacat tgcttggtag ttgtgagtgt tgataacacc tgcaggagaa cctggaacga
    11161 tcgtacggac gtattcttgg tttccgttgc gaagtgttcc gataacccac tctacgttct
    11221 tcatacgtgc tggtggaaga gaaccatgaa cagtcgacat acggctacct gattgaggtg
    11281 gtacacgttt agcgaacata gtgtctggat cttggtgagc gttgttgtag tagaggaatt
    11341 ggttgttgtc gtcagcgtat gtcaattcaa atggcatagc tttcaagaac atatcaattt
    11401 ggttaactgt taggataccg tggtccaatt tgacataggt atcaccagaa acagcaccag
    11461 tgattgctgc aactttttct acccattctg gatcgtcagg gtcaacttct gtgatggttg
    11521 tagcgattgg ttttccacaa tccaagtctt ctgattcgat tggttttggt tttttcaatt
    11581 tcgaaacgac tcctacgtat ttaacaaagt tatctaagca agtttcaagg aatttaacag
    11641 tgccttcgtt ggtgatattt ccgttgttat caaaagcttc cttagcttta ccaagaagga
    11701 attcgttacc tggaagcgtg taggcattaa cacctggagc atcaaggatt ttacgaaggt
    11761 gaacttgagc acgtgatgtt ccttggtcat agtatgatgc acccacaatc ataacaggct
    11821 tgttttcaaa tggatgaact tcgtatgaaa gccattcaag tacagatttg agtgaagctg
    11881 agatagtgtg gttgtgctca ggagtggcga taatgacacc atcagcacgt gtaatcttgt
    11941 tatacaagaa acgcaattgg aagctttcgt cccatttttc gtcttggtta aacattggaa
    12001 cttcgtcgat ttcaagtact tctaattcaa atttgaattt gaaattgcga cggataaatt
    12061 ccaagagttt gcggttatat gattgatcgt agtttgatcc aacaagtcca acaaatttca
    12121 ttctttcggt ctcctatctt acaaattttc ccagtcaaat tcttctgcat ctttgcgaag
    12181 caattcttgc gcattgcgca atttctcagt aatcttcacg aagatacgga agtcatcaaa
    12241 gatggcatcc aatttcttga taacatcaag gtcaaccaag tcgccacttg ggttaaatga
    12301 ttgaagagag tgtgagagca agaattcatc tggaagaaca tttgccttga tttcaggagc
    12361 attcaagatt tgacgaagtt gcaattgggc acgagatgaa ccaagcgtac cgtaagaagc
    12421 acctgtaatc atgattggtt tgttcaaaag tgggtagata ccgtaagata gccaagcaag
    12481 agcactcatc aaaacagctg gaatagagtg atcatactca ggagtaccga taataacgcc
    12541 atctgcctct tcgattttag cagcaatttc caatatttca gcaggtactt gcttgtcagc
    12601 tggtttgttg aagacaggaa tggccttgat ttcaacaagc tcaatttcag ctttgtcagc
    12661 aaagtgtttt tgcatgtatt gaagcaattg acggtttgta gaacgttttg aatttgttcc
    12721 aacaatagca ataagtttta acatgagatt tcctttctct ttttacataa tacaatttta
    12781 aaattccatt gaaacagttg tctctataga gtaggaattc ctgaagaaca gcttaggtgg
    12841 ccttctttat cgatgaggat aacttcgatg ccctccaaac tttcgacttg ccagaggata
    12901 gaagcaggtc tttctccaaa gagtcgagtc gtccagattt cgccatcgac tgatttatca
    12961 gagatgattg ttagactcgc tagttccgtt tcaacaggat atcctgtttg actgtcaaaa
    13021 atgtgatggt aatcttgtcc atcgacggtc aggtgacgtt cataaatgcc tgaagtcacg
    13081 acagatttat tgacaacagg gatggtcatt aaatgatttc ccctaggatt ggctgggtct
    13141 tgaatcccga tttgccatgg gttatcccct cttgcctgat tttttccaat ggtcaggata
    13201 ttccctccca gattgatcaa ggcagaagtc accccctctt tcctaagaaa ttgggcaacc
    13261 ttatccgcac tgtatccttt ggctaaacaa cctagatcga tcttcattcc tttctgtttt
    13321 aaaaacacag tagaagtaga agaatctaac tcgatatcat gaggattgat tagaggcagc
    13381 accgattcaa tctcttgagg ctgggcgacc ttggcatctg aaaaaccgat acgccaggtt
    13441 tgaattaagg gaccaatgct gatattgagg tggctagaga gcgctaggct atgctctaac
    13501 ccaagtgaaa tcagctcaaa caggtctgga tgaaccgtga cgggggctat tcctgcttga
    13561 taattgattt ccatcaactc agattcttga ctattggcgt tgaagcggta ttcaagttct
    13621 ttgagcaagt caaaggactt ttggagaaag atatcggctt gctcatccac taatgaaata
    13681 gtgatagtag tccccattag ccgttcagaa tgtgaacgaa gagtcaagct accaactcct
    13741 ttctcttata gaaaataagt tgtaatatca aataattatc taaattgaag cccttacatt
    13801 ttattttcat gttattataa taccataaag ttagaatttt cacaaacaaa atttggaaaa
    13861 agtcaagaaa tatgctcata aaattcatga ggcttgaaaa caggataaat ggggaattat
    13921 ttttgataaa aaatgctgaa ataatagtac cccccttgta aacgctaacg gtaaatggta
    13981 tactagtaaa gtaaatttag aatgaaggca ggaaattttt tatgagtaaa atcgttgtag
    14041 tcggtgctaa ccacgctggt acagcatgta tcaataccat gttggataat tttggaaatg
    14101 agaacgaaat tgttgtattt gaccaaaact ctaacatctc ttttctagga tgtggaatgg
    14161 ctctttggat tggtgaacaa attgacggtg ctgaaggctt gttctattct gataaagaaa
    14221 aattggaagc taaaggtgct aaagtttaca tgaactcacc tgttctttca atcgactatg
    14281 ataacaaagt agttatagcg gaagttgaag gaaaagaaca caaagaatca tacgagaaat
    14341 tgattttcgc tacaggttct acaccaatct tgccaccaat cgaaggtgtt gaaattgtta
    14401 aaggaaaccg cgaatttaaa gcaactcttg aaaatgttca attcgtgaaa ttgtaccaaa
    14461 atgctgaaga agttatcaat aaactttctg acaagagcca acacctcgac cgtatcgccg
    14521 ttgttggtgg tggttacatc ggtgttgaac ttgctgaggc ctttgaacgt cttggaaaag
    14581 aagttgtcct tgttgatatc gttgatactg tcttgaacgg ttactatgac aaagacttca
    14641 cacaaatgat ggcgaagaac ttggaagatc acaacatccg cttggctcta ggtcaaactg
    14701 ttaaagcaat cgaaggtgac ggtaaagttg aacgcttgat tactgacaaa gaaagctttg
    14761 acgtggatat ggttatcctt gcagttggtt tccgtccaaa cacagccctt gctgatggta
    14821 agatcgaact cttccgcaac ggtgccttcc ttgtagacaa gaaacaagaa acatctatcc
    14881 caggcgttta cgctgttggt gactgtgcga ctgtttatga caatgctcgt aaagatacaa
    14941 gctatatcgc tcttgcttca aatgctgttc gcactggtat cgttggtgcc tacaacgctt
    15001 gtggacatga attggaagga atcggtgttc aaggttcaaa tggtatctca atctacggtc
    15061 ttcacatggt ttcaactggt ttgactcttg aaaaagcgaa agctgctggt tacaacgcaa
    15121 ctgaaacagg ctttaacgat cttcaaaaac cagaattcat gaaacatgac aaccatgaag
    15181 tagcaattaa gattgtcttt gacaaagata gccgtgaaat tcttggtgcc caaatggttt
    15241 cccatgatat tgcaattagc atgggaatcc acatgttctc acttgctatc caagagcatg
    15301 tgacaattga taaattggca ttgacagacc tcttcttctt gccacacttc aacaaaccat
    15361 acaactacat cacaatggct gcccttacgg ctgaaaaata aaaatgaatg agctatctgg
    15421 ccttaagtta aggtcagata gtttttagct aatctgtccc catacaatta tagttttttt
    15481 atcttgtgct tcattctgtt ctgacttaaa atgaaaaggt agctaccaat acaaatgatg
    15541 aggataaaac aaatgactga aaatcgttat gaactaaata aaaacttggc acagatgctc
    15601 aagggtggtg ttattatgga tgtgcagaat cctgaacagg ctcgtatcgc agaagctgct
    15661 ggtgcggcag ctgtgatggc cttggaacga attccggctg atattcgtgc agctggagga
    15721 gtttcccgca tgagcgaccc aaagatgatt aaggaaatcc aagaagcggt tagtattcca
    15781 gtaatggcta aggtcagaat cgggcatttt gttgaagctc agattttaga ggctattgaa
    15841 attgattata tcgacgagag tgaagttcta tctccagctg atgaccgttt ccatgtggac
    15901 aagaaagaat tccaagttcc ttttgtctgt ggtgctaagg atttgggtga agccttgcgt
    15961 cgtatcgctg aaggtgcttc catgattcgt accaaaggag aaccagggac aggggatatc
    16021 gtccaagctg ttcgtcatat gcgtatgatg aatcaggaaa ttcgccgcat tcaaaactta
    16081 cgtgaggacg agctttatgt tgctgccaag gatttgcaag tccctgtaga attggtccaa
    16141 tatgttcatg aacatggaaa attgccagtt gtaaatttcg ctgctggagg tgttgcaacg
    16201 ccagcagatg ctgcgttaat gatgcaacta ggggcagagg gggtctttgt cggttcaggt
    16261 attttcaagt caggagatcc tgttaaacga gcgagtgcca ttgttaaggc tgtgactaac
    16321 ttccgtaatc ctcaaatcct agctcaaatc tctgaagatt taggagaagc catggttggt
    16381 attaatgaaa atgaaatcca aattctcatg gctgaacgag gaaaatagat gaaaatcgga
    16441 atattggcct tgcaaggggc ctttgcagaa catgcaaaag tgctagatca attaggtgtc
    16501 gagagtgtag aactcagaaa tctagatgat tttcagcaag atcagagtga cttgtcgggt
    16561 ttgattttgc ctggtggtga gtctacaacc atgggcaagc tcttacgtga ccagaacatg
    16621 ctacttccca tccgagaagc cattctatct ggcttaccag tgtttgggac ctgtgcgggc
    16681 ttaattttgc tggctaagga aatcacttct cagaaagaga gtcatctagg aactatggat
    16741 atggtggtcg agcgtaatgc ttatgggcgc caattaggaa gtttctacac ggaagcagaa
    16801 tgtaagggag ttggcaagat tccaatgacc tttatccgtg gtccaattat cagcagtgtt
    16861 ggagaagatg tagaaattct agcaacagtt gataatcaaa tcgttgcagc ccaagaaaaa
    16921 aatatgttgg taacttcttt tcatccagaa ttgacagatg atgctcactt acaccagtac
    16981 tttatcgaaa tgtgtaaaga aaaaagacag taaaaaagct caaaaaatca cttcctgtgc
    17041 tatactgtaa ttgaaatttt tttagttttt gcgttagaac tgtttcctca gtcctagcgc
    17101 cttttctttt tgataagtct gcttggtgga gagtagtttg taaacgattc tgagaatctt
    17161 atgagcacaa gcaatgacgg ctttcatctt gcttcctctt tgggaaattc gattgtaaaa
    17221 ctctaagcag gctctgcctg cttagagttt tacatatgct actatctttg ttatagctaa
    17281 cttaaattct catttattaa gtatacctaa gttttatgtt taaattttgt atagaatagt
    17341 tgtatcactt aacaaagcta tgtttacgct ttcaatcaag tctcatttat gatactatta
    17401 tggtaataga aaaaattctt agttcgctaa agacctttat tcgagatcca gaggaaatag
    17461 aaattttatc cattaaaaat acgtttcata agttacttac ttgatattaa tagaattcca
    17521 atattgtata attaaatcaa agatgacact ggaatcagga ggatttatta tggttaataa
    17581 tgtagctgtt aaagtctcaa acctttcaaa agaatttttg ttagggcaag acaaaactgt
    17641 ctctattttg aaagatattt ccttatctgt caattatggg gaatttgtat caatacttgg
    17701 tgtcagtggt tctggaaagt ctactttgct aagttgctta tcaagtttat ctgaaccaac
    17761 aagtggcgaa gttgttatca atggtgtaaa tccatatacc ttaaaagaag ggaagcttgc
    17821 taaatttaga agacaagata ttgcaataat ttttcaaaac tataatctgg tacctgctct
    17881 acctgtacta gaaaatgtta cacttcctct gagactatca ggaaagagtg ttgatagcaa
    17941 taaagtaaaa aaaatgttgg atagtttgaa ttttaaagca gaactatcat cattagttgc
    18001 taccttatca ggtggagaac agcaaaaagt ggctattact cgtgcaataa tagctgatag
    18061 taaaattatt tttgctgatg agccaacagg agctctggac agcgtctcaa gaaaacttat
    18121 atttgaaaca cttcgtaatt tagcgagtca aggaaaatgt gttcttatgg tcactcatga
    18181 tattgagttg gcttcaaaaa ctgacagagc actcatttta aaagacggaa aaatatctcg
    18241 acaaattatt aaaccttcag ctgatgagct ctaccaagca cttgaaagta gtaaagatta
    18301 atttgaggag gatttattat gctaaaatta atcatttacc aatttcagta ctcaaaaaga
    18361 caatggttag gaacaatacc attactattt gtatctagcc tgattgttgg aacatcttta
    18421 tttggtattg ctagttcaat caagactgct aatattaacg cttcacaact ttttcaaatg
    18481 ctaataattt ttggcgggac tactctattt ttccttattt caaataatat aagactgcta
    18541 atagatatct ttaaaaagga ttaccaatta tggactatct taggcgcaag cagaactcag
    18601 ctatctttat tagtatctgg acagttttat ttaatggcag tgattgttag tagtattggt
    18661 acaatacttt catttatcat ggcagatagt tattacaaat ttttacaaaa tttattagga
    18721 agagatgagt tacctgattt agttattaca gccaacattc aatcaatttt attgagta
//
LOCUS       DAVKXA010000043        18728 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKXA010000043 DAVKXA010000000
VERSION     DAVKXA010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18728
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.043"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            122..277
                     /locus_tag="VW883_001599"
                     /pseudo
     CDS             122..277
                     /locus_tag="VW883_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VW883_001600"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VW883_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0274708.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKISSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLTNLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWNVFLKEGVVTKQLQDLTATMEAIEQERQAEVWKAFCHVL
                     EQFATVFAGSQISLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKIAQNTSLLTDEERQNINQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLVLSAPSLFNESESKESAYLQELVHLGFSRKEKRMNHKRLSKEDMGSYHSLLSSL
                     VAYHQQGETSDTEQDLTFVKVLARVMGKKLDQQGLENPALPTSPSSKQLTKDTLQALY
                     PAEQEFYLSTSGLTEFYRNQYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PDEDSFDNRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPVIE
                     TIKEEANFGGKEQAFIQLDNGRSVFVRGKVDRIDRLKADGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VW883_001601"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VW883_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0274709.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQVMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWVISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALETLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="VW883_001602"
     CDS             7614..8792
                     /locus_tag="VW883_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274710.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9001..14892
                     /gene="iga"
                     /locus_tag="VW883_001603"
     CDS             9001..14892
                     /gene="iga"
                     /locus_tag="VW883_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HEV0274711.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRKETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVN
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEESSNPSDS
                     TTSVGESNRPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     SPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPAVKLTELY
                     LEEQFSKTKQNLGGSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     HHGTTDLFSALETYRKVFLPNTSNNDWFKKQTKAFIVEEKSTIAEVKAKQKQAGTKYS
                     IGVYDRITSNTWKYRNMVLPLLTLPERSVFVISTLSSLGFGAYDRYRNSEHKAGKDLN
                     NFVEENASETAKRQRDHYDYWYRILDNEGREKLYRTILLYDAYKFGDDTTSGKATVEA
                     KFDSSNPAMKNFFGPVGNKVVHNHHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPYDATITINSILKHSKSDSLEGSRLQVL
                     DPTERFQNSADLQNYVHNMFDLIYMLEYLEGQSIVKKLNVSQKMEALRKIENQYLTDP
                     ADGNEVYATNVVKELTEEEARNLNSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEGIAKQNGQTINLYGK
                     KQGLVTDKLVLEKIFSGKYPSWTAFKKAMYQERIAQFDHLTKVIFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            14944..15147
                     /locus_tag="VW883_001604"
     CDS             14944..15147
                     /locus_tag="VW883_001604"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0274712.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVRNSFLLPLKSHHLMAFFYIG"
     gene            15314..16165
                     /gene="ylqF"
                     /locus_tag="VW883_001605"
     CDS             15314..16165
                     /gene="ylqF"
                     /locus_tag="VW883_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0274713.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETFRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            16152..16931
                     /locus_tag="VW883_001606"
     CDS             16152..16931
                     /locus_tag="VW883_001606"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0274714.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQSLSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            16947..18497
                     /locus_tag="VW883_001607"
     CDS             16947..18497
                     /locus_tag="VW883_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0274715.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         6079 a         3662 c         3889 g         5098 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagcaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtgatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct acccgtcgac attaagacac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atatgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cggacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 accatgagat gaccaaatct cagatgaatt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaagataa
     1021 gtagtgattt taatcaaatc gccttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaaccc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagtat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg actaatcttc ttagaactga tttgtatact gacctcagtc
     1681 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1741 cctttcagca aaccttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgtct gagaatttta gcacctcttg aaaccctctt tgctagccga aaacaaaagg
     1861 ccgaaaatct cttgcaaaag tggaatgtct ttctaaaaga aggagtggtg accaagcagt
     1921 tacaagattt gacagccact atggaagcta tagaacagga aagacaagcc gaggtttgga
     1981 aggcattctg tcatgtttta gaacaatttg cgactgtttt tgctggttca cagattagtc
     2041 tagaggactt cctagccttg ctccattctg gaatgagttt gtctcagtat cgcactattc
     2101 cagcgacagt ggacaccgtt ctggtgcaga gttacgattt gattgcgcct ttgactgctg
     2161 actttgtcta cgccattggg ctaactcagg acaatttacc aaaaatcgcg caaaatacca
     2221 gtcttttgac agatgaagaa agacaaaaca taaaccaagc gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tctttggtca
     2341 attctgcccg taagcaatta gttttgtcgg ctccaagcct ttttaatgaa agtgaaagca
     2401 aggagtcagc ctatcttcaa gagttggtcc atttgggatt tagtcgaaaa gagaagagga
     2461 tgaatcacaa aaggctgtct aaggaagata tgggatccta tcacagtctt ttgtccagtc
     2521 tggttgccta tcaccagcag ggcgagacga gtgatactga gcaagatttg acctttgtca
     2581 aggttctggc gcgtgtgatg ggtaaaaaac tagaccagca aggtttggaa aatcctgccc
     2641 ttccaaccag tccaagcagt aagcagttga ccaaagatac cttacaagct ctctatcctg
     2701 ctgaacagga attttaccta tctacgtccg gtttgaccga gttttacaga aaccaataca
     2761 gttatttcct ccgctacgtg ttaggcttgc aggaggaatt acgtttgcgt ccggatgctc
     2821 gcagtcatgg aaatttcttg caccgcattt ttgaacgtgc cttgcagttg cctgatgaag
     2881 attcctttga caaccgtcta gaacaagcta ttcaagaaac tagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa agaagttttg cttgatgttg
     3001 cacggacgac tggtcacatt ctccgccata atccagtcat cgaaaccatt aaagaagagg
     3061 caaatttcgg tgggaaagag caagccttta ttcaattgga caatggacgc agtgtctttg
     3121 tacgaggtaa ggtggaccgg attgaccgtt tgaaagctga tggagcgata ggagtagtag
     3181 actacaagtc gagtctaact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggga gcagaatttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggcgaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaagttgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggc
     3721 ttgaaaaaat aagagaggag ttgaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 gcaaatcgaa gctatctaca cttctggcca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca aatgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgacctca aacaacactt
     4081 gggacgccag ttggcagacc taccaaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agacctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc gccagcaggt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctttggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagtccg atagtcaggc
     4621 ttatcaggca gtgcttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgagccct
     4681 gactaatgcc agtcgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttgctaaac taggacaatt atcagaccag ataaccattc tcgactatca
     4801 agaacgttat catcaagaca catgggaact agctaaaacc ttccaaacct ttatgagtca
     4861 ttttgtggag gcttatcgtc agcgcaaacg ccaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatccccaa gaaggcaagc tcattctcct caaggaaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg gattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aagtcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 aacccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaatcca aggaataccc
     6481 agcagccaaa aatgggaaac tgaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gttatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaac
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagat
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agcactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt cgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgactgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatt ggccgtagca
     7741 attgtgtctg tggaaatgcc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgtaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat caaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaagc agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaaatggtg
     8581 aagtaccctt ttcaactgaa tacctgtcag atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacca tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataattaa ggtatactgc cttttctata gataatagat
     8941 aatacactaa tataataaag gtctttgtaa catatataaa ttttatttca aggaggaata
     9001 atggaaaagt attttggtga aaaacaagag cgtttttcat ttagaaaatt atcagtagga
     9061 cttgtatctg caacgatttc aagtttattt tttatgtctg tattagctag ttcatctgtg
     9121 gatgctcaag aaactgcggg agttcactat aaatatgtgg cagattcaga gctatcatca
     9181 gaagaaaaga agcagcttgt ctatgatatt ccgacatacg tggagaatga tgatgaaact
     9241 tattatcttg tttataagtt aaattctcaa aatcaactgg cggaattacc aaatactgga
     9301 agcaagaatg agaggcaagc cctagttgct ggtgctagct tagctgctct gggaatttta
     9361 atttttgctg tttccaagaa aaaggttaag aataaaacgg tattacattt agtattggtt
     9421 gcgggaatag gaaatggtgt cttagtttca gtccatgctt tagaaaatca tcttttgcta
     9481 aattacaata cggactatga attgacctct ggagaaaaat tacctcttcc taaagagatt
     9541 tcaggttaca cttatattgg atatatcaaa gagggaaaaa cgacttctga ttttgaagta
     9601 agtaatcaag aaaaatcagc agccactcct acaaaacaac aaaaggtgga ttataatgtt
     9661 acaccaaatt ttgtagacca tccatcaaca gtacaagcta ttcaggaaca aacacctgtt
     9721 tcttcaacta agccgacaga agttcaagta gttgaaaaac ctttctctac tgaattaatc
     9781 aatccaagaa aagaagagaa acaatcttca gattctcaag aacaattagc cgaacataag
     9841 aatctagaaa cgaagaaaga ggagaagatt tctccaaaag aaaagactgg ggtaaataca
     9901 ttaaatccac aggatgaagt tttatcaggt caattgaaca aacctgaact cttatatcgt
     9961 aaggaaacta tagagataaa aatagatttt caagaagaaa ttcaagaaaa tcctgattta
    10021 gttgaaggaa ttgtaagagt aaaacaagaa ggtaaattag gtaagaaagt tgaaatcgtc
    10081 agaatattct ctgtaaacaa ggaagaagtt tcgcgagaaa ttgtttcaac ttcaacgact
    10141 gcgcctattc caagaatagt cgaaaaaggt actaaaaaaa ctcaagttat aaaggaacaa
    10201 cctgagactg gtgtagaaca taaggacgta cagtctggag ctattgttga acccgcaatt
    10261 cagcctgagt tgcccgaagc tgtagtaagt gacaaaggcg taccagaagt tcaaccagcg
    10321 ttgtccaaag cagttataac cgacaaaggt gagactgagg ttcaaccaga gtcgccagat
    10381 actgtggtaa gtgataaagg tgaacctgaa caggtagcac cgcttccaga atataagggt
    10441 aatattgagc aagtaaaacc tgaaactccg gttgagaaga ccaaagaaca aggtccagaa
    10501 aaaactgaag aagttccagt aaatccaaca gaagaaacac cagtaaatcc aaatgaaggt
    10561 actacagaag gaacctcaat tcaagaagca gaaaatccag ttcaacctgc agaagaatca
    10621 acaacgaatt cagagaaagt atcaccagat acatctagcg aaaatactgg ggaagagtcc
    10681 agtaatccta gtgattcgac aacctcagtt ggagaatcaa atagaccaga acataatgac
    10741 tctaaaaatg aaaattcaga aaaaactgta gaagaagttc cagtaaatcc aaatgaaggc
    10801 acagtagaag gtacctcaaa tcaagaaaca gaaaaaccag ttcaacctgc agaagaaaca
    10861 caaacaaact ctgggaaaat agctaacgaa aatactggag aagtatccaa taaacctagt
    10921 gattcaaaac caccagttga agaatcaaat caaccagaaa aaaacggaac tgcaacaaaa
    10981 ccagaaaatt caggtaatac aacatcagag aatggacaaa cagaaccaga gaaaaaactc
    11041 gaattaagaa atgtttctga tattgagttg tatagtcaga cgaatggaac ctacagacaa
    11101 catgtttcat tggatggaat tccagagaat acggatactt actttgtcaa ggtaaaatct
    11161 tcagcattta aagatgtcta tataccagta gcttcaataa ctgaagagaa aagaaatggg
    11221 cagtcagttt ataaaatcac agccaaagct gagaaactcc agcaagaact agaaaataaa
    11281 tatgtcgaca atttcacctt ctacctcgat aagaaggcta aagaggaaaa tacaaacttt
    11341 acttccttta gcaacctggt caaagctata aaccaaaatc cctctggaac ctatcattta
    11401 gcggccagcc tgaatgctaa cgaagtggag cttagtactg atgataaatc ctatatcaag
    11461 ggaaccttta ctggtcagtt gattggtgaa aaagatggta agcattatgc tatttacaac
    11521 ttgaaaaagc ctctttttga aaacttgagt ggtgctacag tagaaaaact gagtctaaaa
    11581 aatgttgcta tttcagggaa aaatgatatt ggttcactgg caaatgaagc tacgaatggc
    11641 acaaagatta aacaagttca tgttgatggt gttctggctg gagaacgtgg tgtcggtggt
    11701 ttgttggcta aggcagacca atcaagcatc gcagagagca gtttcaaggg aagaattgtc
    11761 aatacctatg aaacgactga ttcctacaat attggcggtc tggtcggtca tttaacagga
    11821 aaaaatgcgt ctattgctaa atccaaagcg acagtaacca tttcgtcaaa caccaatagg
    11881 tcagatcaga ctgtcggtgg tcttgcaggt ctagtagacc gagatgcaca gatccaagat
    11941 agctatgctg aaggtgatat caacaatgtc aagcactttg gtagagtcgc tggagtggca
    12001 ggcaatttgt gggatcgaac ttctggtgat gttaggcatg ctggaagttt gaccaatgtt
    12061 ctcagcgatg ttaatgtaac aaacggaaat gccatcactg gataccacta tacaggaatg
    12121 aaggtagcta atacatttag tagtaaggct aatagagttt tcaatgtcac tttagagaag
    12181 gatgaggtcg tcagcaagga atcctttgaa gaaagaggaa caatgctaga tgcttctcaa
    12241 attgtaagca aaaaagcaga aataagtcct ctcactctac caacggtgga acccctctca
    12301 acaagtggca agaaagacag tgatttttct aagatagccc attatcaagc taaccgtgct
    12361 ttggtttata agaacattga aaaattgtta cctttttata ataagtcaac catcgtgaaa
    12421 tacggaaacc tggttaagga gaacagtctc ttataccaaa aagaactctt atctgcagtt
    12481 atgatgaagg atgaccaagt aatcacagat attgtttcca acaaacagac tgcaaacaaa
    12541 ctcttacttc actataatga ccattcatct gagaaatttg atctcaagta ccagactgat
    12601 tttgccaatc tagcagaata taatctaggt aatacgggac ttctctacac tcctaaccaa
    12661 ttcttatatg atcgagactc tattgttaag gaagtcttgc ctgagttgca gaagcttgat
    12721 taccagtcag atgctatcag aaagacactt ggtatttctc cagcagttaa gttaaccgag
    12781 ctctatttag aagagcagtt ctccaaaaca aaacaaaatc tgggaggcag cttgaaaaaa
    12841 cttttgtcag cagatgccgg tctagctagc gataactcag tcaccagagg ctatcttgta
    12901 gataaaatca agaataataa ggaagccttg ctactcggtt taacttattt agaacgttgg
    12961 tataacttta actatggtca agtgaatgtc aaagacctag ttatgtatca tccagacttc
    13021 tttggtaaag gaaatacttc cccactagat actctgattg agttaggtaa atctggcttt
    13081 aacaatcttc ttgccaagaa caatgtcgat acttatggta tcagtctagc cagccatcat
    13141 ggaacgacag atttgtttag cgcacttgaa acttaccgaa aagtcttttt accaaacact
    13201 agcaacaatg actggtttaa aaaacagacc aaagctttca ttgtcgaaga aaaatccact
    13261 attgcagagg tcaaagccaa gcaaaagcaa gcaggaacta agtactctat cggtgtttat
    13321 gaccgaatta ctagtaatac ttggaagtac cggaatatgg tcttgcctct ccttaccttg
    13381 ccagaaagat ctgtatttgt catctcaacc ttgtctagtc taggatttgg tgcttacgat
    13441 cgctaccgta atagtgaaca taaagcaggc aaggacctca ataatttcgt tgaagaaaat
    13501 gcgagtgaaa ctgccaaacg tcagcgagat cactacgatt attggtatcg cattttagat
    13561 aatgagggac gtgaaaaact atatcgtacg attctccttt atgatgccta taagtttggt
    13621 gatgacacaa catctggaaa agctacagtg gaggctaagt ttgatagctc caatccagcc
    13681 atgaagaatt tctttggtcc agttggtaat aaggttgttc ataatcatca cggtgcctac
    13741 gcaacaggag atggtgtcta ctatatgtct taccgcatgc tcgacaagga tggagccatt
    13801 acctataccc atgagatgac ccatgattcg gatcaagata tttaccttgg cggctatggt
    13861 cgaagaagtg gtcttggtcc tgagttcttt gctaaaggtt tattacaagc gccagaccat
    13921 ccatatgatg cgaccattac cattaactct atcttgaaac attcaaaatc agatagctta
    13981 gaaggatcgc gtctgcaagt cttggatccg acagaaagat tccaaaactc agcagatctt
    14041 caaaactatg ttcacaacat gtttgacctc atctatatgt tggaatatct agaagggcaa
    14101 tcgattgtta agaaactgaa tgtttctcag aaaatggaag ctctcagaaa aatcgagaat
    14161 caatatctaa cagatcctgc tgatggaaat gaggtttacg ctactaacgt agtcaaagaa
    14221 ttgacagaag aagaggcccg aaacctgaat agttttgata gtttgattga caataatatt
    14281 ctttcagctc gtgagtataa ggctggtaca tatgagagaa atggctactt tactataaaa
    14341 ctctttgcac caatcttttc agcattgagc agtgagaaag gtactcctgg agatcttatg
    14401 ggacgaagga tagcttatga actcttagct gctaaaggat ttaaagatgg tatggtacca
    14461 tatatttcca accaatatga aggaattgct aaacaaaatg gtcagacaat caacctttac
    14521 ggtaaaaagc aaggattagt gacagataag cttgttttgg aaaagatatt ctctggcaag
    14581 tatccatctt ggacagcttt taaaaaagct atgtatcaag agcgtattgc tcagtttgat
    14641 catttgacta aagttatttt taaagatccg acaaaaccat ggccaagcta tggcacaaag
    14701 actatcaata atgtggatga attgcaagcc ctcatggacc aagctgttct caaggatgct
    14761 gaaggtccac gttggagtaa ttataatcca gaaatcgaca gtgccgttca taagttgaag
    14821 agagcaatct ttaaagccta tcttgaccaa acaaatgatt ttagaagttc aatttttgag
    14881 aataaaaaat agtgtttact attaggaaat aaagtttaaa aaggtgatga agaacaaacc
    14941 aagattcaag caggaattcc tactgataat gaagtaagtt atgctcttat ttatcaacag
    15001 gaaactcttc ctgcaacagg ttcatcaact tctgcgctta cagctttagg cctattagct
    15061 gttggtagtt tagttctttt ggttcggaac agttttttgc tccctctgaa aagtcatcat
    15121 ttgatggctt ttttctatat agggtaaaag atagggtaaa aggctatcat cggacaaaat
    15181 aaagaaggca tgatataata taaagtagat ttttatgtca taaaacaaga actgtttgga
    15241 catcattcat ttttagattg agatctctta gttctagatt aacagcttca gagctacgaa
    15301 aggaaaaaac tcaatggcta ctattcaatg gtttcctggt cacatgtcta aagctcgtcg
    15361 acaggtgcag gagaatttaa aatttgttga ttttgtgacg attttagtag atgcacgctt
    15421 gcctctatct agtcaaaatc ctatgttgac caagattgtt ggtgataaac caaaactctt
    15481 gattttaaac aaggccgact tggctgatcc agcaatgacc aaggaatggc gtcagtattt
    15541 tgaatcacaa ggaatccaga cgctagctat caactccaaa gagcaagtga ctgtaaaagt
    15601 tgtaacagat gcggccaaga agctcatggc tgataagatt gctcgccaga aagaacgtgg
    15661 gattcagatt gaaacctttc gtactatgat tatcgggatt ccaaacgctg gtaaatcaac
    15721 tctgatgaac cgtttggctg gtaaaaagat tgctgttgtt ggaaacaagc caggggtcac
    15781 aaaaggtcaa caatggctta aaaccaataa agacctggaa atcttggata caccggggat
    15841 tctctggcct aagtttgagg atgaaactgt tgcacttaag ttggcattga ctggagctat
    15901 caaggatcag ttgcttccta tggatgaggt taccattttt ggtatcaatt atttcaaaga
    15961 acattatcca gaaaagctgg ctgaacgctt caaacaaatg aaaattgaag aagaagcgcc
    16021 tgtgattatt atggatatga cccgcgccct cggtttccgt gatgactatg accgttttta
    16081 cagtctcttc gtgaaggaag tccgtgatgg caaactcggt aactatacct tagatacatt
    16141 ggaagacctc gatggcaacg attaaagaaa tcaaagaact ccttgtgaca gtcaaggagt
    16201 tagaaagccc tattttttta gagcttgaaa aggataatcg ctcaggagtt caaaaggaaa
    16261 tcagcaagcg taaaagagcc attcaagctg aattagatga aaatttgcgc ttggaatcca
    16321 tgctttctta tgaaaaagaa ctttataagc aaggattgac cttaattgta ggtattgatg
    16381 aggttggtcg tggtcctctt gctggtcctg tagtcgctgc ggccgtcatt ttacctaaaa
    16441 attgtaagat taaaggtctc aacgacagca agaaaattcc taaaaagaaa catctggaga
    16501 ttttccaagc cgttcaagac caatccttgt cgattggaat tggtatcata gataatcagg
    16561 tcatcgacca agtcaacatc tatgaagcaa ccaaactagc catgcaagaa gcaatctccc
    16621 agctcagccc tcaaccagag caccttttga ttgatgccat gaaactggac ttgcccattt
    16681 cacaaacctc cattatcaaa ggagatgcca actccctctc tatcgcagca gcatctatag
    16741 tagccaaggt aacacgtgat gaattgatga aggaatacga tcagcagttc cctggctatg
    16801 atttcgctac taatgcagga tatggcacag ctaaacatct ggaaggcctc acaaaactag
    16861 gagttacccc aattcaccga accagctttg aacccgttaa atcactggtt ttaggtaaaa
    16921 aagaaagtta attgaaagga aataccatgg aggaacagtc ggaaatagtc cgttctaaga
    16981 aagaattcgc ctttgcatcc agcactatac tatcccaagt tggtcgagga atcattgtcg
    17041 gcctcatcgt tggaattatc gtcggatcct ttcgtttctt aattgaaaag ggcttccacc
    17101 tgatacaagg agtttatcaa gatcaagggt acttagtgcg caatcttttt gtactggttt
    17161 tgttttatat actcatctgt tggctcagtg ccaaactaac acggtcagaa aaagatatta
    17221 aaggctcagg aattcctcaa gtcgaagccg aactgaaagg cctcatgtcc ctcaactggt
    17281 ggggcattct ttggaaaaaa tatgtactag gtattcttgc tattgccagt ggactcatgc
    17341 tgggtcgaga gggacccagt attcaacttg gagcagttgg tggtaaagga attgccaagt
    17401 ggctcaaatc cagtccagta gaggaacgtt ccttgattgc cagtggagct gcagcaggtt
    17461 tagccgcagc ctttaatgct cctattgcag cacttctctt tgttgtagaa gaagtctatc
    17521 accatttttc gcgctttttc tgggtctcaa ctctagcagc cagcatcgta gcaaactttg
    17581 tgtctctact catgttcggt ttgacaccag tattggatat gccagataac attcctccca
    17641 tgaccctaga tcagtattgg atatatctcg tcatgggaat tttccttgga ttttcaggct
    17701 ttctctatga gaaagctgta ttaaacgttg gaagagttta tgacttgatt ggtcaaaaaa
    17761 tccatttgga tagagcttat tatcccatct tggcttttat ccttatcata ccagtcggaa
    17821 tcttcttacc tcaaatcatt ggtggcggaa atcagcttgt cctttcttta actgaacaaa
    17881 attttagttt ccaagtttta ttagcttact ttttgatccg ctttatttgg agtatgatta
    17941 gctatggaag tggactgcca ggaggaattt tcctccccat tttagctctt ggttctttgc
    18001 ttggtgcctt aattggtgct atctgtgtca atcttggact tgtcagtcaa gagcaattcc
    18061 ctatatttgt cattctagga atgagtggct attttggagc catatcaaaa gctcccttaa
    18121 ccgctatgat cctcgtaact gagatggtag gagatattcg caacctcatg ccacttggtc
    18181 ttgtcactct tgtttcttat attatcatgg atttgctcaa aggtacgcca gtctatgaag
    18241 ccatgctgga aaaaatgctt ccagaagaag tatctagcga aggagaagtt acacttatcg
    18301 aaataccagt ttctgataaa attgctggga aacaagttca tgaactcaac ttaccacaca
    18361 acgtcctcat cacaactcaa gtccataatg gcaagagcca aacagttaac ggctcaacca
    18421 gaatgtatct gggtgatatg attcacctgg ttattccaaa aagtgaaatt ggaaaagtca
    18481 aagatttgtt gttgtagtac aatcatttac ataatttatg ttatgtaaat gctcagcttg
    18541 atttatttag aaaaccgatt ctcagaaatg agatcggtta ttttttactg atgaggaatt
    18601 ttacatataa ataattgaac tttattaaaa ataagactat aattaagtta gaaatgataa
    18661 agcataaagc tagaaaggag tttactgtat caaatctgta cagtaagatt aaaatcatga
    18721 aaaagaaa
//
LOCUS       DAVKXA010000044        18523 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKXA010000044 DAVKXA010000000
VERSION     DAVKXA010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18523
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.044"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..785)
                     /gene="lytB"
                     /locus_tag="VW883_001608"
     CDS             complement(<1..785)
                     /gene="lytB"
                     /locus_tag="VW883_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0274716.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYL"
     gene            complement(827..1765)
                     /locus_tag="VW883_001609"
     CDS             complement(827..1765)
                     /locus_tag="VW883_001609"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0274717.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPVIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1776..2576)
                     /locus_tag="VW883_001610"
     CDS             complement(1776..2576)
                     /locus_tag="VW883_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0274718.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2826..3206)
                     /locus_tag="VW883_001611"
     CDS             complement(2826..3206)
                     /locus_tag="VW883_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0274719.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3264..3623)
                     /gene="rplT"
                     /locus_tag="VW883_001612"
     CDS             complement(3264..3623)
                     /gene="rplT"
                     /locus_tag="VW883_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0274720.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3675..3875)
                     /gene="rpmI"
                     /locus_tag="VW883_001613"
     CDS             complement(3675..3875)
                     /gene="rpmI"
                     /locus_tag="VW883_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0274721.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3908..4438)
                     /gene="infC"
                     /locus_tag="VW883_001614"
     CDS             complement(3908..4438)
                     /gene="infC"
                     /locus_tag="VW883_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0274722.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4454..4585)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4745..5926)
                     /locus_tag="VW883_001615"
     CDS             complement(4745..5926)
                     /locus_tag="VW883_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274723.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYFNSQTANSVS
                     LERELETRLVDRERVINEYEAKLSQMSDTSSEEYQFAKSNLELQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     gene            complement(5930..6517)
                     /locus_tag="VW883_001616"
     CDS             complement(5930..6517)
                     /locus_tag="VW883_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274724.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6550..6738)
                     /locus_tag="VW883_001617"
     CDS             complement(6550..6738)
                     /locus_tag="VW883_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274725.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6927..9167)
                     /locus_tag="VW883_001618"
     CDS             complement(6927..9167)
                     /locus_tag="VW883_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0274726.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9151..9801)
                     /locus_tag="VW883_001619"
     CDS             complement(9151..9801)
                     /locus_tag="VW883_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV0274727.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKTVSGIGAKTIEKLKDYVTVD"
     gene            complement(9869..10438)
                     /locus_tag="VW883_001620"
     CDS             complement(9869..10438)
                     /locus_tag="VW883_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274728.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10615..11726
                     /gene="ald"
                     /locus_tag="VW883_001621"
                     /pseudo
     CDS             10615..11726
                     /gene="ald"
                     /locus_tag="VW883_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072563.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12093..12353)
                     /locus_tag="VW883_001622"
                     /pseudo
     CDS             complement(12093..12353)
                     /locus_tag="VW883_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12356..12856)
                     /locus_tag="VW883_001623"
     CDS             complement(12356..12856)
                     /locus_tag="VW883_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274729.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            12892..13071
                     /locus_tag="VW883_001624"
     CDS             12892..13071
                     /locus_tag="VW883_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274730.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(13049..14017)
                     /locus_tag="VW883_001625"
     CDS             complement(13049..14017)
                     /locus_tag="VW883_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0274731.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14103..14318)
                     /locus_tag="VW883_001626"
     CDS             complement(14103..14318)
                     /locus_tag="VW883_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0274732.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14327..15181)
                     /gene="cvfB"
                     /locus_tag="VW883_001627"
     CDS             complement(14327..15181)
                     /gene="cvfB"
                     /locus_tag="VW883_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0274733.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15241..15798)
                     /gene="frr"
                     /locus_tag="VW883_001628"
     CDS             complement(15241..15798)
                     /gene="frr"
                     /locus_tag="VW883_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0274734.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASELGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15807..16544)
                     /locus_tag="VW883_001629"
     CDS             complement(15807..16544)
                     /locus_tag="VW883_001629"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0274735.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16628..17962)
                     /gene="trmFO"
                     /locus_tag="VW883_001630"
     CDS             complement(16628..17962)
                     /gene="trmFO"
                     /locus_tag="VW883_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0274736.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18207..18461)
                     /locus_tag="VW883_001631"
     CDS             complement(18207..18461)
                     /locus_tag="VW883_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0274737.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         5327 a         4194 c         3433 g         5569 t
ORIGIN      
        1 ttgaggtaaa accaagattc cttatcccaa atccattcat tggctgccat gtagccaccg
       61 gattttagat aataatagtg accattctcg aaaatccatt ctttatcagc atagtttcca
      121 ttttctttga tgtaaaacca agattggtat tgtttgtcaa aaagccaacc ttgctgtact
      181 ttggcaccac tagcattcac ataagcttga ttaatccact gacttgtcag tagataacca
      241 ccggatttga aataatagtc cttcccttta atttggagcc attctttctc tgcgtgctgt
      301 ccatctgctt tgatataaaa ccaagcatcg tattgagaat catagaccca gtcttctatt
      361 actttagcac ctgttgcacc aacataggaa gttcctaccc aagcatttct tttcatcttt
      421 ccatcttggt caagataata aaaggctccc ttgtcttcta cccattctga tttggccata
      481 tagccaccag atttgaggta aaaatagtcg tcaccttgct ttagccattc attttcagca
      541 tagttagcat ctgcttttat atagaaccaa gattgataat gagtatcaaa aacccactca
      601 ttcgctgctt gactgccatc ttctttcaga tactgttttc cttgccaagt accatcacta
      661 gccattgcac cctctggact agctaagaaa aatagcagag ctaaaaaaat aaatcttact
      721 ttcttcatta accttcttcc tctgttctta tttattttat tgtaccaaaa ttctcctaaa
      781 ttcatattac aaactaataa aaaatcaaga acagattgat tgcagtttac ctcagagact
      841 cttttacttc ctgacggagt tcttccagac tgctaatacc gtatttatcc atgacttttg
      901 gtaaattttc gatgatgaca ggacaggcat aaggattggt aaagttagct gttccaactc
      961 cgatagcaga tgccccagcc agatacattt ctagggcagc ttcagccgaa tccactcccc
     1021 ccattccaat gataggcagg tctgttgttt gggctacttg gcggatgagt ttgagggcta
     1081 ctggaaagac tgctggacct gacattccac ctgttccatt ggccaagatt ggttttctgg
     1141 ttttgaggtc aaagcgcatt ccaaccagag tattgatcat ggtcaagcca cttgctcccg
     1201 catcttctgc agcttttgcg acagtaacga tatcggtcac actcggggtt aatttgacat
     1261 aaactggcac ttctgaggct tccacagctg ctttcaccac atcataagcc aaatctggat
     1321 cttgaccaat caaaagtcca tgattacagt ggtcaacatt gggacaagaa atattgagct
     1381 cgatagcttt tacattagtt gccttggaaa tcccatgaga aacagctgca tactcttgtt
     1441 ttgaaaaacc agctacattg gcaataatag gaagatttgg atattctctt tccagccaag
     1501 gtagcttttc agccaaaaca acctctaaac caggattttg caagccaatt gcattgagca
     1561 taccagcagg cgtctctgcc actcttggag ttggattccc aaaacgtggt tcaagggttg
     1621 tcgccttgat cataatagaa cctaaaaggt ctaaatcata gtacttggca tactcttgtc
     1681 caaagccaaa acagcctgat gctggaataa tcggattttt caaatccaaa ccaggtagag
     1741 acacttgtaa tcgatttgta gtcataattt tctccttata atacaactgt tcctgtgcgg
     1801 aaaacaggac catcttcaca gacgcgttgg ctgaccgtct cgctttctgg tacttttaga
     1861 acacaggcat agcaagctcc catcccacaa gccatacgag attccagaga taaataggct
     1921 cttgggtgat catcaaaggt ttgattgata tacttcatca ttcctggagc cccacacgag
     1981 taaacagcat caaactgact atctaaatca ttgataacaa cggaaacatt tcccttgatg
     2041 ccataagaac catcatctgt cgttacaaag acctgaccat actgagccaa ttccgttttc
     2101 aaaataacag catccttatt agcaaaaccg aggactgtca ctactttcac tccacgtcca
     2161 tgcaattcct tggccacctc aagcaagggt ggaacaccaa tcccaccacc aacaaggaga
     2221 acctgattct gctcatcaag gtcagacaag tcaaaaccat ttccctgagg ccccatcaca
     2281 tcaagagtgt ctccctgact taaggttgaa aaaattgcag tcccagctcc ctcaatccga
     2341 taaatgaggt gacactgctt gtttgccttg tcaatagacg aaattgaaat aggacgacgt
     2401 aagagatggg catcgtccgg tacacgcaga tgaagaaatt ggcctgctcg catggcttca
     2461 accatttctc cttctagaac taattcaaag attgctggcg cgatttcctc ttgtgcaacc
     2521 accttcatgg tttccaaccg aatgacaccc aaacgcttct tacatgtggg attcataact
     2581 tttcctcctt aaattttaag gggaccagat aaagaaaaga ccttgctagt gcaaggcctc
     2641 agttaaaatc gtacaacaca agagagcaca ctcaaaaagt ctcctctaga aaattgcact
     2701 attcttttat ctgacacctt gtgagtctct ctggactccc cttaaaggtt gaatttttat
     2761 tagtatactc tttcagctaa aaaaagtcaa gtagaaaacg aatattctac ttaacttgca
     2821 cgaaattatt tttcacgaat gacttcgacc ttatatccat cagggtcttt gacaaagtaa
     2881 tagtttggtg tagttcctgg tagaccattt ggctcagtca cttcatagcc ttttgcactg
     2941 tgttcttgat gaagtgcctc aagatcaggt gtactgaggg cgatatgggc aaacccatca
     3001 ccaaccacat acggaccgtg atcgtagtta taagtcaact ccaactcata atcatcaccc
     3061 tcaagaccta gatagacaat cgtgaaggca tggtctggaa aatctctgcg acgcaattct
     3121 ttaaaaccaa aagcatcttg atagaatgca attgattttt caagattttc tactcgtaag
     3181 caagtgtgta gcatttttga agccatactt ttctccttta tttttaaaaa gactggacaa
     3241 tcctgttcca gtctcatcag ttgttattta ccaagttttg ctttagctgc atctgcaaga
     3301 gctgtgaaag ctactgcatc gttaacagcc aagtcagcaa gcattttacg gttaacttcg
     3361 atctcagcca atttcaaacc atgcatcaat tgtgagtatg aaagtccgtt catacgagct
     3421 gccgcattga tacgagtgat ccacaatttg cggaagtcac gttttttctg acgacggtca
     3481 cggtatgcat agtagtaaga gttcattact tgttcttttg cagtacggaa caagatgtgt
     3541 ttagctccat agtaaccttt tgctaattta agaatacgtt tacgacgttt gcgtgataca
     3601 acgccacctt taacacgtgc catgttttat ttcctccaaa tatttcctag aattgtttac
     3661 ttacagtcaa gctattattt caagcgagta agcattgctt tgatacgttt gtaatctcct
     3721 gaatgcacca tagatgcttt acgaagatga cgacgttgtt tcttagtttt tccgtggaaa
     3781 cggtgagaag tgtaagcacg gaaacgttta agtccaccag aacctgtacg tttgaaacgt
     3841 ttagctgatg cgcggtgtgt tttttgtttt ggcatgattt tttctccttt atttaacttt
     3901 ctgacaatta ttttttgtca gtcgctggcg ccaattgcat gaacatttga cgtccatcca
     3961 ttttagcacg ttgttcgatg atggcaatat cttgagttgc ttcagcaaac tcggctaaaa
     4021 cttttgcacc aatctcttta tgggtaatca tacgaccctt aaagcgaata gataccttaa
     4081 ctttatttcc tttttcaagg aacttacgtg cattacgaag ttttgtatca aagtcaccct
     4141 tgtcaattgt tggacttaga cgaacttctt tcacagtaac aacgctttgt tttttacgtt
     4201 gttctttttg cttcttctgg tactcaaatt tgaacttacc gtagtccata atttttgcaa
     4261 caggcggttt ggcttggggt tgaatcaata ctaggtcaac attagcgtta tcagccaaag
     4321 cttgcgcttc actgagtggc ttgatgccta gctgttctcc ctcaagacca atcaagcgaa
     4381 cttcacgtac acgaatctca tcattgatga ataagtcttg ctttgctatg gttttcacct
     4441 cttttgtttt attagagaaa aacaatagcg gactcgtaaa tatacaagcc cgcacgttat
     4501 gatagcgttt cttcgaaact tttcatccgt agggccaggc aacttaatgt cacaaggcga
     4561 gaagctctca cttctgcttt tctcaacttt tatatgatac caagttttct agctcttgtc
     4621 aagataaaaa gttatttttt gaaaagtttg tgtttgtatt ttggtttggt tttcgaatca
     4681 aaaagagaga accaagttga ttctctccct atgttagttt ttctttagct tccctatagg
     4741 aaaactaaac tttaaaaact tcctttttac gtgaacttcc ccatctttcg ataaatagaa
     4801 tccccactaa caaaaggata atcaggcaag gaagtaagac catccccatg ctccaattta
     4861 gatcgacatt atcaatctgc ttagataatc ttccagataa aatctccact gaacgcaagt
     4921 aagtaaaggg aatcagatgt gcaatccttt gaagaggctg aatggtttgg atgccaaaca
     4981 ataagccaac aatcccaatg agtgaaagaa agaggacagg cattttttgc ttgaaaaagt
     5041 aagcaatcaa gtacacaact tccacaatga cgataaaggc taagaaagct aagagcaagc
     5101 caggaaataa tacatcttgt attttcccaa tagttacttc ttgattcact aagctataaa
     5161 ttgggtaggg ataatctaac tgtccaaaac cacttatcag acttcccact agaaaagaaa
     5221 agccacagat tccgataaac agcacagtta catatcccac tccaactcca agagaggata
     5281 ttgcaaatgt cacttttgaa acaggatata agtgagctgt gtccagatga ttttgatatc
     5341 tttctgcaaa tagttgtgtt agcataaaaa taatcgcaac cacaaacaag cttgggatga
     5401 taacctctaa aatccagaca atctgatcaa tcccgtgggt cggaaactcc aaagtatgtg
     5461 cttttatgtt caagggatac agggcttggt aaatcttccg ttcgcggtca acccccattt
     5521 ttaagccaga gctagcagtc gggtcatttg atacaaattc ataattcttc tcttcatctt
     5581 gccactgcag atagtaggcc tctttccagc gcccttcttt taataaagtc agaatttctg
     5641 tctttcgctt caaaagattt ttttgcaatt ctaaattact tttagcaaac tggtattcct
     5701 ccgagctggt gtcagacatt tgggaaagtt tcgcttcata ttcattgatg actctctcac
     5761 ggtctacaag acgagtttcc aactctctct ccaagctgac tgagtttgca gtctgactat
     5821 taaaataaaa agtaacaccg agtacagata caaataaagc taagataatc cagtttaagc
     5881 ggcttttgaa aacttttttc aataaaaata gactaacatc tttcataaac taaacctctt
     5941 ctatctgccc ctgatgaatg gttactactc tatcgcagac atcaaccaac tcttccttat
     6001 agtgggaact taaaagaacc agctgttctt gtctatcgat ttgtgctagc ctatcaaaaa
     6061 acttctgtcg ataatactca tctaagccat ttgtaatctc atccatgagc cagcatttgg
     6121 cctgactgag gaaatacatg gcaatcacca agcgttgctt catgcctaag gaatacttgc
     6181 gaatgggaag actgatatag tcagacattt cccaataggc gatttcatcc ctcaagttca
     6241 gacctgactt ccagatgttt ttgataagac gaaggtagtc catcccactt aagtttccat
     6301 ccagccattc aatactctca taataaaata aagaaggagg ggctgcgata tttccactac
     6361 ttatgggaat taaattgcta atggcacgga atagggtcgt ctttccagag ccattgatag
     6421 caagaagacc ataaacccta ccctttttaa aggtgaaatc cacatcttgc aagatgactt
     6481 gtcgcgtttt taaggtcaca tgagtaagct gcaacatatc tagccctcct ttttctcact
     6541 ctctaagaat taatagcctc cgctgtaata gtttatgacc tcataacgac cgtagttcca
     6601 gcctccgcca actttatact cagaatagct gtcataacga gaccatgacg gaatccaagc
     6661 atactgatgg tcgtgatagt tggtactata ttcccaaacc gtattccaat catacttgta
     6721 acttttagtg actgtcacag cagatacact ggactgaaga agaccaatag attataaact
     6781 aactaattaa acgatttttg ctaattttta atgattttta atgattttat atcctcaata
     6841 ttgaatacgt tttcattata ccatttttat cattattatg caacaaattt ttagtttatt
     6901 tcactaatct acaacattta tccttcctat cgaacacttt cgattttcca actatccaac
     6961 cccttaaaac gtatagctcc ttgctggtca gttcgataaa ctttgctatt gataccttcc
     7021 agtcgtgtca atgtttcctg atgggggagt ttcattcgat tgctctttcc aactgagata
     7081 agagtaagct ctggtttgag tttttctaga aaggctggac ttgatgattt tttattgcca
     7141 tgttggctag ctttcaaaac atttactttc aagtctggat agtgcttcag caagtccttc
     7201 tctcctttct cctccaaatt tcccgtgaag agaaattgct tatccaagaa tttcccatac
     7261 agaactaggg tatcatcgtg tcctccatct cccattttcc ttggagatag aacttctaac
     7321 tgacttccaa aaatgggcaa gttctcccct actgtcatac tacgcacctt tgtttgagtc
     7381 gcctgtagtt ctgccacaaa ttccttctgt ttcagactgt cttttgatac tagaatctcc
     7441 cctacatgga aagccttggt cacctctgac aaatctccaa cattctcctt gtccgtgtta
     7501 gtcaaaatta gctggtcaat cttagctact cctcgacttt tgagataggg aatcaaggtt
     7561 cgctgggcat tgctggtcgt catcttttct tgccattttt cgattttctt ataagattct
     7621 gccttaccac ctacatctat gagaatggtt ttcccagtta catcccgtag gaaaatactt
     7681 tctccttgcc ccacatccag catggtgatt tcattttcca gtggatgctt ggtcaggaga
     7741 aagagccctg taatcaataa gcacaatacc gttagctttt taatgttttt tctcagatca
     7801 tagaccaaag ccaaggaaat taacaatagg attaaaaacc atgcattggg ttgtccaaag
     7861 accagaggtc tacttgtcac ctgtgacacc aagcgaataa tgccctccaa ccattcaaag
     7921 ataaagttca gctgaatgac tggatagaga aaggaaagga caaataaaat agacaagagc
     7981 ggtaagaagg tcaagtcaaa tagaaaggaa aagacaaagg tcaaaaggat agaccaaggt
     8041 tgaaattccg caaaatagaa ggatagaatg ggcaatatgc ccaaggagat gactagactt
     8101 tcactagtaa cagccttgag cccctcccct tctttgctgg tcatggtcag gataaaagca
     8161 taagcgcagg acaagactcc tcctgctgtc aagaaaaagt ttggcatgac aataaagagg
     8221 acaagcaccg tcaaggcaaa attatccaag cccttaaccc catgttgagc cagtagcttt
     8281 tgcaagagac tgcgaataac cgatgctgaa aatccagtta gtcccgcata gataagggaa
     8341 aagggataag tcagccattt caacttttct tgggtcaagc ccaatcgcaa gagaagtttc
     8401 ttaaatccat tcatgaaaaa acctacctgc ataccagata gggcaaagag gtggataatt
     8461 cctagactgg aataaagctc attcatctcc tcaaagtcgg tgtccagatg tcccagcaag
     8521 agtcctgtca tgtaattgcg catagggtct ggaaagtgcg tcttaatcca aaccacagcc
     8581 tttcgacgta aactggacaa gttttctcct atatcccaac tgccaatctt ttgaagtgac
     8641 tggattgttt tgatattgag agtctggtaa attccctgag tcttcagata ggcttggtaa
     8701 ttaaagccac caaaatttct ctgcccttct ggctccgaaa gcttcccttc tagtcctatc
     8761 tcatgcaggt cggttaaagc ttgaaaggct tctttctcct cctcggactg gagtttataa
     8821 tagacttgga aagcacgacc gttagacttg ccacgaaagg atagactatc accattaacc
     8881 ttaatagtat caggtaaaat ccgtaccctt tcaacagaat ccgccagatt ttgactcgct
     8941 tgactctgtt gccaattttg aaaaacaaac caaaatccaa agattccgca aattattaga
     9001 actttaccag cagatttcca cggaaattgg ataaagagac agactagcag aaaaacaaag
     9061 cccaacaaag caagatagga tgctgagaaa atagcgtaat aaaaccaaag taacaaaaaa
     9121 ctcaggtaaa ttaggggaat ggggatgttc ttaatccact gtaacatagt cttttagctt
     9181 ttctatggtc ttagcaccaa tgccagagac tgtcttgagt tcgtctactg acttgaactt
     9241 gccatttgtt tcacgatggt cgataatatc ctgagcacgt tttcctccca gtcctttgac
     9301 ctgcttgagt tcttccagac tggccttgtt gagattgacc ttcttttcct tgcttgttga
     9361 agaagctgtc cccgaaccag tctgttgact aactgcttct tctcccttag taggaacgta
     9421 aaccagagcc tcatcactaa ctttctgagc tagattgagc gacttgctgt ctgcttgctc
     9481 tgtcaagcca ccagccttct gaacagcatc attgactcga ctacctacag gcaagtcata
     9541 aatccctggc gatttgacag cacctttgac atctactgtg attagatctt gttcaagggg
     9601 ttcttccttt tcttccttct tcacttcctt ttcggtcgat gagtccttgg aaacagctgc
     9661 aacttcagcc tgcaaattcg tctctttgac aggtgtttgt ggagctggtt ttagcaggaa
     9721 aaatcctcct acaagcaagc ccagaccagt acagatgacg atgattttat actctttgat
     9781 tttctcgata attgcttcca tattttctcc tctcttagat tattcgtaag aggaagaaaa
     9841 aacagtcgaa aaatttcttt tcaactgctt atttatttgc aaaatagtct tccttggtca
     9901 agacataatg aactcttgtc acgattcggc ctttttcatg ctggtccata caagcatatg
     9961 gttctgcatg ggaaaaacgc atgcctgatt tctccatgac ctttcctgac gcaggattgt
    10021 ccttatcgtg aagggcagtc aacttattca tccctatctt ctcaaaagct agctcaatca
    10081 cagcacgatt ggcttctgtc gttaatcctt gattccaata ctttttattg ataatgtagc
    10141 caatagctgc cttcttaaga acagaatcaa tcttgtgcaa gtcaatggtt ccaataaact
    10201 gaccattgct ttttagttct attccccaac gtcccaaggg attagccaaa tagaactgag
    10261 caatgttatt cttggtttct tccaagcttt gattggttgg aaaagtgtaa cgtgtattac
    10321 ccttgtccga ggcatagtca aacattgctt ccgcatcatc caaagttaca ggtctaagca
    10381 ataaacgctc cgtttctata gacggatact gggcaagttt tacaaaaatt gattccatac
    10441 ttttccctcc attagagctt gattttcact agtctagcat aaaaaaattg ggatgacaag
    10501 tttttcttga tttttgaagc ggtttcatat acaatgaaac cgtcacattt ttgatttatg
    10561 aactggaatg tgacaaccaa aacaagaccg tcaattgaaa ggtaggttat ctcaatgtta
    10621 atcggaatcc caaaagaaat taaaaataac gaaaaccgtg tcgccctcac acctgcaggt
    10681 gttcatagct tagttagtcg tggtcatcgt gtccttatcg aaacaaatgc tggtctcggt
    10741 tctggcttta ctgatgctga ctatcaaaag caaggagctg agattgtcgc tactgctggt
    10801 gaagcttggg cagcagagtt ggttgtgaaa gtaaaagaac ctttaagttc tgaatacggt
    10861 tacttgcgcg acgatcttct tctcttcacc tacttgcaca tggccgctgc tccagaatta
    10921 gcagatgcta tgttagcagc aaaaacaaca ggaattgcct atgaaactgt tcgtgacaat
    10981 caaggacaac taccgctcct cgttcctatg agtgaggttg caggtcgtat ggctgttcaa
    11041 atcggagctc acttccttac taagcaagct ggtggctctg gtgttctact tggtggtgta
    11101 ccaggtgttc caaaaggaaa agtaactatc atcggtgatg gtgtcgtcgg tacacatgct
    11161 gcccgcatcg cccttggtct tggtgctcaa gtgactattt tagatattag tgccaagcgt
    11221 ctctcagttc tagaagaagt ctttggaagt caaattcaaa ctcttatgtc taattcattc
    11281 aacattgaag caagtgtgag agatgctgat gtggtgattg gagccattct catccctggt
    11341 gcaaaagcac cggaattggt gacagatgag atggtcaaac aaatgcgtcc aggctctgta
    11401 tcgttgacgt tgctgttgac caaggtggcc ttatcgaaac agctgaccgt gtgacaacgc
    11461 acgatgaacc cgtctatgaa aaacacggtg ttctccacta tgccgttgcc aatatccctg
    11521 gtgcggttgc ccgcacttca accatcgccc taaccaatgt cactcttcct tatatcgaag
    11581 ctttggctgg caaaggattc gcacaagcaa tctctgaaga tgaaggcttg cgtcaaggtg
    11641 tgactactta tcaaggttac ttgactaacc taccagttgc tcaaggactt aatcgtgact
    11701 acactgatat caatgattta gtataaattt taaaaagaaa agggtgactt cgcaagtcct
    11761 acccactgtg ctttgtgtca tcagctatta catcgttggt ttattgtact gtatactttg
    11821 caactggaga ctttcgttcc agactcaatt gtgcataaga aactctaaat tgaataaagt
    11881 caacagagtt tcgcccaacc acttcgtctt gtaatgacaa ttatataaac caaaggaagc
    11941 tgagctcttt agtcccagct tctttttata tataaaattt tacccgtgca aagacagggc
    12001 cttagcagac ttctttttta cttcgttcac ccttgctttt tctttttagg tttgggcgtt
    12061 ggcagttggt tatacatagc taaaatcagg tcttatagaa acatcttatt atcaagttct
    12121 tccactcaaa tcatttcttt ggcacctttg tatggaaact caaaagaaga ttggtcaatc
    12181 ttatctaaga ctgcttgcac gggtttaact aaaaagcgat cgtcataaat gccgccaata
    12241 atcttgccgc ggaagtaaag aatatactcc cccatcatgg aacggtaagt cacatcatct
    12301 aatcctgata attgttccaa aacaaattcc aaatagttct tacttgatgc catttctaat
    12361 cttctaggct ctgttcagcg ataacaaccg tatagagttc ttgcttaacc tcgcatccaa
    12421 ttgatttaaa gccctgcttt tcccaaaaat gctgagattg cggatttccc ttaacataag
    12481 ccaaacgtgc ctttcgaaag ttcttagcaa aataagctag tgcttctgtc acaatatgac
    12541 taccaatccc tttcctctga taggcttgat caaccataaa caaaccaata aaaacagtct
    12601 cctcatcagg atatgcatag acaaaatcca taacagccac aaggtcagat ccattccaaa
    12661 atccaacaaa aaacttatca gccttagctt taccttcagg tagacaaagc atgtcctctt
    12721 ttacagttgc aaaatttggt tctggtggac aatgctgaaa atacagagga ttactttcat
    12781 ataaagataa aatacttgga atatcctttt cagttagtat cctacaactg taatacttag
    12841 atagttggtc aatcatcttt tcaaattcct actttcttgt gccctgtgat tatgacacag
    12901 gaagatgcac tgatcgtcat cagccacata aaagttcttt ccatcgtgcc taatcgttgt
    12961 ctcagacctt tggataaaac ctttagccta tacaactgga ttttcctctc tcaaaagtat
    13021 attcttttgc aggcgaactt cctcaaaatc agtcgtgtgc aacttcagta gaatattcat
    13081 aggctcggat aatctgagcg acaactggat ggcgaaccac atccttggct gaaaaatgaa
    13141 caaagtcaat ctgatggatg ttcttgagtt tctcttgagc atcaatcaaa ccggacttga
    13201 cattacgtgg caggtcaatc tgactgatat ctccattgac aatcatctta gaatgaaagc
    13261 ctaaacgcgt caagaacatc ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa
    13321 tgacaaaggc atcatccaag gtccggccac gcatataggc aaggggcgca atttcgataa
    13381 tttcacgctc catgagacga gtcgtttggt ctttcccaag aatttgatac aaggcatcgt
    13441 aaacaggacg aaggtaagga tccaccttct ccttaagatc acccggaaga aatccaagac
    13501 tctctcccgc ttccaccgct ggacgagtta ggataattcg cttgacttgc ccacgtttaa
    13561 gggcagtcac tgccaaggtc actgcaagga aggtcttccc tgtacctgct ggcccaattc
    13621 caaaggtcac atcatgctgt ttgacactgt ccacataaag cttttgccct agtgttttga
    13681 cacggatagg tttcccagta ttatctttga taatttcttc ttcgtaaagg gcgacaaact
    13741 tgtcaatttc atcatttttg accatgctaa tcgcagtgac tacatctggc gtaccaacgg
    13801 tcatcccacg atttaccaag accatcaaag cctgaataac ttgacgggct tcctcacagg
    13861 cagactcttc tcccaaaacc tggacaatct ccgtacgagc atgaatcaca acatcaagct
    13921 cttcttccat caaacgaaga tggcgttcat tggaaccaaa aagatgaaac aggtcatctg
    13981 gatgactcag ttgaatgtct attgaatgtt ccttcaaata aagaacctct ctaatccttt
    14041 tatttctttt tattatagca gagggatgga gaaattacta gcccaaaccc aatgaataaa
    14101 tgctagtgtt ctagatattc ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa
    14161 ctggcatgct cctccaaaaa gcgactgacc tcatcaaaat catctgtatg ttttggaaaa
    14221 gctgcctctt caaaagcgag gtctgccaaa attgctttgg gactgttact tttaggattg
    14281 cgctcggtca tgagccaagt gtaaaatgat tttctcataa gcctccctaa atcaactctg
    14341 tcccaaactg gtcctgcttg attttaccag ccttcataag accacctaaa gctttcttga
    14401 actgaccttt agaaatgcca aaggttgcct tgatgtcgtc tggagatgac ttatcattta
    14461 aggtcatgaa accgccatta ctttccaaat aagtcaaaat catctgagca tcgttttcca
    14521 acatttcaaa ggagcgtggt ttgagggaga ggttcagagt gcggtccact tcacggaaac
    14581 caataacgcg cgcatctaat acttgcccca aacgtggctc tgcgtaacgc tcgctaggat
    14641 gaataaaacc aagcatatta ttttctggta ggtaaacaaa agttcctgac agcttgagac
    14701 ggtaaacaat ggctggccag ttttggttct gcatgttgtt gtaggcagga cgagcaagac
    14761 gttggaagtc ttcttgataa gccaagaggc cccagatacg gtctttctta tccacttcaa
    14821 gacggatgta gagttggtcg cccttcttag gccagagttc cttgagctca gggagaatat
    14881 cgagtgacac aacgatttcc ttgtcaggaa ggcctgtatc cacaaagaca cccaaatcct
    14941 tacgaacctc tgtgacacgt ccccaaccaa attggtcctg agtggcagtc acttctaagg
    15001 ttgtcaggcg gagtttttgc ttcatatccg tgtatgcaaa acctttgacc gtatccccta
    15061 ctgtatgttg accttcttcc ttagcaagag cataggtttg accatccttt tgcacaaagt
    15121 aaaaacggtc attttcatcg atgatcagtc caacgataaa acttgcaaga tttgtattca
    15181 tatttccttc tttcgaataa aactcagcca gcaatgccaa ctgagttttt ctgtttattt
    15241 ttagacttcc aaaagttctt tctctttgtt agcagtcatg tcgtcgatgt gtttaacagc
    15301 atcgtctgtt actttttgaa tatctttttc aagagtcttc aattcgtctt cagtgatttc
    15361 ttttgctttt tcttgtttct tagcttcgtc catagcatcg cgacggatat tgcggacagc
    15421 cactttagca ttttcgccga ccttcttcac ttctttagca aggtcacgac gagtttcttc
    15481 tgtaagagct gggataacca agcgaatcac agaaccgtca ttagccggtg tgataccaag
    15541 ttcagaagcg ttcaaggcac gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac
    15601 caacaaaaca cgcgcttctg gaatcgtaat tgaagcgatt tggttaagag gagtttcgac
    15661 tccatagtat tctacatgta cacggtcaag caagcttgca ttggcacgac cagcacggat
    15721 accaccaaat tcacgagcaa gtgattggtg agattgggtc attctctctt tagctttttc
    15781 aataattacg ttagccatat tctttcttat tccttttctt cgatattatt tgaaactgtt
    15841 gttccgatat tttcaccaaa tacgacacgt ttgatgttgc ctgattggtt catgttgaag
    15901 acaaccaagt caatgtcgtt gtccattgag agggttgagg ctgttgagtc catgatacga
    15961 agacctttgt tgataacatc acggtgggtc aattcttcaa acttaacggc tgtcttgtcc
    16021 ttcttaggat cggcattgta cacaccatcg acgccatttt tagccatgag gatggcatct
    16081 gcttcgattt cagctgcacg aagggccgct gttgtatctg tcgagaagta tggtgaacca
    16141 attccagcac caaagataac gatacggcct ttttcaaggt gacgaagggc acgtccacgg
    16201 acataaggct ctgccacttg ttgcatagca atagctgttt gtacacgcgt atcaacccca
    16261 acttgttgca atgaatctgc catcacaaga gcattcataa cagtcccaag cattccagtg
    16321 taatctgcct gaacacggtc catacctgct tctgctgcag gttctccacg ccaaagattt
    16381 cctccaccaa taacaagggc aatttcgata cctaagctat gaacttcttg aatctctttt
    16441 gcgattgttt gaactgtttg gatatcaatc cctacgccac gttcaccggc aagggcttca
    16501 cctgataact tgattaaaat acgtttatac ttgggattcg ccattttcac tctccttctt
    16561 tcatcctacc tattttatca caatttctaa gatttttata gtatcatgag caattctttc
    16621 aaaaaaatta gacagtcaaa aattcctcta agtcggcaag ggcacgctct gcaatttttt
    16681 cataacgagc cttcttatca cggatacgct cgccttccaa ctccttgatg atcccaaaat
    16741 tgacattcat tggttggaaa tgtttgctgt cggcatgggt aatgtaatga gctaagcttc
    16801 caatcgctgt cgtctcgggg aaaataacct cgctttcttc cttgaagaga cgagctgcgt
    16861 taattcccgc aactaagccc gaagccgccg actcaacata gccttccacc cccgtcatct
    16921 gaccagcaaa gaagagattt ggttgtttct tggaacggta agtctgctca agaagatttg
    16981 gtgaatccat gtaagaatta cgatgcatga caccataacg gacaaactcc gcattttcaa
    17041 gacccggaat catttggaag acacgctttt gttctcccca tttgaggtgg gtctggaaac
    17101 caacaatatt gtataggcta ccagctgcat tatcctgacg gagctggaca accgcataag
    17161 gtgttttaaa ttctccatca cgaggtcctg tgtagtcgtc cggatactca agaccaactg
    17221 gtttcatagg accataaagc atggttttaa tgccacgttt ggccatgact tcgataggca
    17281 tacatccttc aaagtacttt tctttttcaa aagaattaag cggtgcttct tctgcattga
    17341 ccaaagcttc atggaaatcc ataaattctt gcttggtcat aggggcattg aggtaggccg
    17401 cttctccctt atcataacgt gatttgaggt agaccttgct catatcgata gtgttgacat
    17461 cgataatagg cgctgccgca tcgtagaaat aaaaaccatc accgtcatta agggcatgaa
    17521 tcttttcagc caaggcatca cttgtcaaag gaccagtagc gataaccgta ataacatctg
    17581 tcggcaattc tgtaatttca tcacgaacca cttcaatcaa ggggtggttg gcaacttttt
    17641 cggtcaccat ttgagagaaa ccatcacggt ccactgcaag ggcaccacct gcaggaacac
    17701 gtgtagcctc agcagattcc aaaatcacag aacccaagcg acgcatttct tccttaagga
    17761 ggccaacagc atttgtcaaa gcatctccac gcaaggaatt ggaacaaacc aactcagcaa
    17821 aattgtctgt tttgtgctga ggtgttgact tgacaccacg catttcataa agtttaactg
    17881 gaataccacg ctctgcgatt tggtaggctg cttcagaacc tgccaaacca gcaccgataa
    17941 cattgatata agattgagac acgacactaa tacctctttg ggagtatgaa gttaagattc
    18001 acattgaaaa agccaatcag acttacgagc tttcgagttt cttggctcag gctgaaaaag
    18061 tccacaggac tttttcactc ccacaaatct ttctattttt tcttctacta gtataacaaa
    18121 aaaagggaag aaggcaaact tccctgttta gtcattttct tgatgtaaag agatagtgag
    18181 tattccagtt aagaatcaat tatatgctac tctataaaat cttttccaca taacggatcg
    18241 atagggactg ttattctatc tcttgctata accgtattat ctaaaacagc ataacattca
    18301 acatagtgat ctcctttaaa ctgtgaatct tcgtgatatt ttattttacc tgaaaaaata
    18361 gcaccacgct cacaatttct tctaatagcc tcagcttcaa tatttcttac tttccaatag
    18421 acttcctgcg aaacaaaata tggtatagta gttctatgaa tgatgaagca agtaaacaac
    18481 taactgatgc acgatttaag cgtcttgttg gtgttcagcg cac
//
LOCUS       DAVKXA010000045        17906 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKXA010000045 DAVKXA010000000
VERSION     DAVKXA010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.045"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(210..1145)
                     /gene="birA"
                     /locus_tag="VW883_001632"
     CDS             complement(210..1145)
                     /gene="birA"
                     /locus_tag="VW883_001632"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HEV0274738.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSSQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1142..2002)
                     /locus_tag="VW883_001633"
     CDS             complement(1142..2002)
                     /locus_tag="VW883_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0274739.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2110..4272
                     /locus_tag="VW883_001634"
     CDS             2110..4272
                     /locus_tag="VW883_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0274740.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4364..5623
                     /locus_tag="VW883_001635"
     CDS             4364..5623
                     /locus_tag="VW883_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0274741.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATDGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATAKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5637..6503
                     /locus_tag="VW883_001636"
     CDS             5637..6503
                     /locus_tag="VW883_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0274742.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6517..7350
                     /locus_tag="VW883_001637"
     CDS             6517..7350
                     /locus_tag="VW883_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0274743.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7661..9103
                     /gene="gtfA"
                     /locus_tag="VW883_001638"
     CDS             7661..9103
                     /gene="gtfA"
                     /locus_tag="VW883_001638"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0274744.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFRDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9241..10434
                     /locus_tag="VW883_001639"
     CDS             9241..10434
                     /locus_tag="VW883_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0274745.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11119..13098
                     /locus_tag="VW883_001640"
     CDS             11119..13098
                     /locus_tag="VW883_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0274746.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13165..14661
                     /locus_tag="VW883_001641"
     CDS             13165..14661
                     /locus_tag="VW883_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274747.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14661..15587
                     /locus_tag="VW883_001642"
     CDS             14661..15587
                     /locus_tag="VW883_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274748.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15596..16663
                     /locus_tag="VW883_001643"
     CDS             15596..16663
                     /locus_tag="VW883_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274749.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPHHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16674..17600
                     /locus_tag="VW883_001644"
     CDS             16674..17600
                     /locus_tag="VW883_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274750.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17675..>17906)
                     /locus_tag="VW883_001645"
     CDS             complement(17675..>17906)
                     /locus_tag="VW883_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274751.1"
                     /translation="HPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLIKLIKRN
                     AFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT         5276 a         3175 c         3751 g         5704 t
ORIGIN      
        1 catatgaatc tttctaatga tggttttgtc gcttttcatt ataggtcata tgggactttt
       61 tttctacaac aaaataggct ccataatatc tataagggat ttacccacta caaatattat
      121 agagacaata aaacttcaga tccgtaaaac ttaattgaat tactaatctg aagttatttt
      181 tatatcgttt atattataat tgtgttattt tacttccaac tattgagaga aatttcgcca
      241 ctatttagcc agatttcttt tccgttatca cattgaacta aaagttttcc attttctgag
      301 atgtctttag caagtccctt gtagtctttt tgctctagtg tgaaagtgac ttcttttcct
      361 agaatgaatg actgtttttt gtataggtat aatagctctt ctgctggtgt ttcgaagaaa
      421 gcacgccaga tttctatgat caattcattc cttgttatag gagctgtagc tttaaataag
      481 ctggcagctt tttcttttaa ttcctgaggg aagtctttaa tagtgaaatt gatacctact
      541 ccaataatga tatctgtgac taagccagtt tctacagagg tcattgcttc agtaaggatt
      601 cctccaattt tatgattgtt tagatagata tcattgaccc attttatgtc gacatctatt
      661 aaagttaggt tcttaatggc tttgtagaca gctccagcta caagtagtgt gtaggatggt
      721 aatttgtcat aggggagatt tggtttaaga tggagtgtca tataaatacc accttgtgat
      781 gagtagaagg aacgttgaaa acggcctcgg cctgctgttt gataggaagc tagatagagg
      841 gtatttgctt catggcctaa atcaattgct tcttttgcat ctagttgtgt tgattttgtt
      901 tcgggtttaa agctgacttt aattggaaga ttttcttcta gaatctctgg aagaataagg
      961 tcaccattca ttagtttata tcctctattt ttgatactat caatttcaat gccttcttgt
     1021 tctagtcgct tgatagcttt ccaaattgat gttcggctta gggatagttt ttctgcgatt
     1081 ttttctccgc tgatatagtc ggtttcttta gataggattt ggtagacagc ttggtaggat
     1141 ttcataatgt tgcctttctc actagttggt attgagagta ttcttttctt gtatgacttg
     1201 gagtctgatt aaagtattgt ttataagctt tcgaaaaatg gagtggatct gaaaaaccta
     1261 ccgagtatgc aattaccttg atggactctt gggtattttc gagaagttgt ctagctcggt
     1321 gcattcgaac gtagagtagg tattctttgg gtgataaggt attaaattct ttgaatacgc
     1381 ttgataagta gcttctgtga acggatagtt cttttgctaa atcttgaatt gtaagtgatt
     1441 gaggatagtg gctatcaatt aatcgtttgc attcaagata gagttggtgg gttgatgaaa
     1501 tattcttttt tttctgattg ggagcaatag ttcccagatg aaacatcagt tcatgaagtt
     1561 gtcccatgat atggagttga gctaattcac ttgattttgt aatctgagcg aagcggacaa
     1621 tgtctgagat gagttttgca gtagtctggg tatgacaagt ttcagattgg atgagatagg
     1681 attgatcaga aatttgagaa agagcaaaat aatcagggga tttccctcca gtgattccta
     1741 accagtagta ggcccaaggt tctttactat ctgcttgata aaaggttagt tcctctggtt
     1801 ttaatagaaa gaaatctcct tcttttaaat caacaatttt acccttgtaa taaaattttc
     1861 cttgtccttt agtaatgtaa tgtagaacgt atgtatcacg aatggctgga ccaaaagagt
     1921 aattaggtgt gcattcctca tatccataaa agcttagggc aaggtcgatt gttccagtct
     1981 ggtattctga aaaaactaac atgtgctacc tcctacctaa cattttacca tattcttgag
     2041 acatttttct attttggaaa gcgatttcag gtgataaaat ataatcaata aagtgatgag
     2101 gtgaagtaaa tgggagttag gatagagaat aatctatttt atgttgagag taaaaatcta
     2161 agtttgatta ttgaaaatcg aaatggctac ttacttttga aacatttagg aaagactatt
     2221 aagaactata aaggttccaa tagtgtttat gaacgagacc atgccttttc aggaaatcca
     2281 acggctacta atcgaacctt tagtttagat actcagcgac agatttttgg acaacatggc
     2341 ttaggagatt ttaggaaacc aaccatacag gttcagcata gtgtaactga agtaacagac
     2401 tttcgatttg tagaagcaaa gattttaaaa ggtcagaatg gtccacaggg cttaccttct
     2461 ccacatagca tggacgatac agagactctt gtcttaatgt tagaagattc taaggctcaa
     2521 cttagtctga ctttgtatta tactactttt aataatgatg cgactattgc tagctacagt
     2581 aaattagata ataatagtaa tcaggaagtt gtcatccata aagatttttc ttttatggct
     2641 gattttccag ctgcagatta cgaaatagta actctgcagg gtgcttatgc tcgtgaaaag
     2701 actgttagac gtcaacaggt agaacaagga atcttttcga ttagctcaaa ccgaggtgct
     2761 tctggtcatg ctcaaacacc agctcttcta ctatgcgaac aaggagtcac agaggatgct
     2821 gggaatgtgt ttgctattca actaatgtat agtggcaact ttgaagcttt tgttcaaaaa
     2881 aatcaattga atgaagttcg ggtggctatt ggcattaatc cagaaaactt ttcttggaag
     2941 ttagcccctg aggaatactt tgaaacaccg gtagctttag tgactcattc agatcaggga
     3001 ttaactggta ttagtcatga aagtcagaat tttgtactga agcacattat gctaagtgaa
     3061 ttttctaaaa aagaacgtcc aattctaatc aataactggg aagctactta ctttgacttt
     3121 cagagagaaa aactgttaga gttagcagat gaagctaaga aagttggcat tgaacttttt
     3181 gtattagatg atggttggtt tggcaatcgt tttgatgata atcgtgcttt aggtgattgg
     3241 gttgttaatg aggaaaaact gggtggaagt ctagaaagtc tgatttcagc tatccatgaa
     3301 agaggtttgc agtttggact ttggttagaa cccgaaatga tttctgtaga tagtgatttg
     3361 tatcgtcaac atcctgactg ggctattcag gttcctgatt atgagcatac ttattctcgg
     3421 aatcaattag tacttaatct tgccaatcct caggtagtag aatacttgaa aagtgtctta
     3481 gatcaactcc tatcttatca tgagattgat tacattaaat gggatatgaa ccgcaatatc
     3541 actaagctag ggaatggatt aacttatcta gagacacaga tgcaatctca tcagtacatg
     3601 ctggggcttt acgaactcgt ttcttatctg acagagaagc acagccatat tctctttgag
     3661 tcctgctctg gtggtggtgg acgaaatgat cttggtatga tacgctattt cccacaagtc
     3721 tgggctagtg ataatactga tgccattgca cgtttaccaa ttcaatacgg ttcatcctat
     3781 ctctatccaa ccatttctat gggggctcat gtgtcagcag taccgaatca tcagatggga
     3841 cgaatgacac cattagaaac acgtggccat gtagcaatga tgggaaattt gggctatgag
     3901 cttgatttga caaatttatc agatgaagag aaagctacga ttgctaatca ggtgaacttg
     3961 tataaagaat tacgaccagt agttcagtta ggacagcagt atagactaat taatcctgat
     4021 actgcatcca atgaagcagc tgtacaattt aattacggaa atcaaacgat tgtaacctac
     4081 gttcgcgttt tatctgttgt agagaccatg gaaacaactt taaaattaaa agatttggat
     4141 gaagagggac tatataaatt acaggaaaat ggcgaagttt actcaggtgc agaactaatg
     4201 tatgcgggct taactgttat cttatcccaa ggagattttt tgagtagaca gtatattttt
     4261 agaaaactat gatatgtact gaccccaaaa gttagattta ttctatctaa cttttgaggt
     4321 gcagtttgat aagggtgtat aaatttataa aggaggcttt ctaatggaat ggtataaaaa
     4381 aatcggactt cttgcaacta caggtttagc tttgtttggg ctcggtgctt gctccaacta
     4441 tggtaaatct gcggatgaca cagtgaccat cgagtatttc aaccagaaaa aagaaatgac
     4501 caaaaccttg gaagaaatca ctcgtgattt tgagaaggaa aaccctaaga taaaggtcaa
     4561 agtcgtcaat gtaccaaatg ctggtgaagt attgaagaca cgcgttctcg caggagatgt
     4621 gcctgatgtg gtcaatattt acccacagtc catcgaactg caagaatggg caaaagcagg
     4681 tgtctttgaa gatttgagta acaaagacta cctgaaacgc gtgaaaaatg gctacgctga
     4741 aaaatatgct gtaaacgaaa aagtttacaa cgttcctttt acagctaatg cttatggaat
     4801 ttactacaac aaagataaat tcgaagaact gggcttgaaa gttcctgaaa cctgggatga
     4861 atttgaacag ttagtcaaag atatcgttgc taaaggacaa acaccatttg gaattgcagg
     4921 tgcagatgct tggacactca atggttacaa tcaattagcc tttgcgacag caacagatgg
     4981 aggaaaagaa gcaaatcaat accttcgtta ttctcaacca aatgccatta aattgtcgga
     5041 tccgattatg aaagatgaca tcaaggtcat ggacatcctt cgcatcaatg gctctaagca
     5101 aaagaactgg gaaggtgctg gctataccga tgttatcgga gccttcgcac gtggggatgt
     5161 cctcatgaca ccaaatgggt cttgggcgat cacagcgatt aatgaacaaa aaccgaactt
     5221 taagattggg accttcatga ttccaggaaa agaaaaagga caaagcttaa ccgttggtgc
     5281 gggagacttg gcatggtcta tctcagccac cgccaaacat ccaaaagaag ccaatgcctt
     5341 tgtggaatat atgacccgtc cagaagtcat gcaaaaatac tacgatgtgg acggatctcc
     5401 aacagcgatc gaaggggtca aacaagcagg agaagattca ccgcttgctg gtatgaccga
     5461 atatgccttt acggatcgtc acttggtctg gttgcaacaa tactggacca gtgaagcaga
     5521 cttccatacc ttgaccatga actatgtctt gaccggtgat aaacaaggca tggtcaatga
     5581 tttgaatgcc ttctttaacc cgatgaaagc ggatgtggat taggagtaga gagactatga
     5641 aaaaagtatt acaaaaatat tgggcatggg cttttgtggt catccccctc ttgttacaag
     5701 caattttctt ctatgtgccg atgtttcaag gagcctttta cagttttacc aactggacag
     5761 gattgactta taactacaaa tttgtcggct taaacaactt taagctcctc ttcatggatc
     5821 caaaattcat gaatgcgatt ggctttaccg caatcattac gattgccatg gtggttggtg
     5881 agattgcact cgggatcttc attgcgcgtg tcttgaattc taaaatcaaa ggccaaacct
     5941 tcttccgtgc ttggttcttc ttcccagctg ttttatctgg tttgacagtg gctttgatct
     6001 tcaagcaagt cttcaactac ggtcttccag cgattgggaa tgcccttcat attgaatttc
     6061 tccaaaccag tcttttaggg actaagtggg gagcaatctt tgcggctgtc tttgtccttc
     6121 tttggcaagg ggtggctatg cccatcatca tcttcctagc tggtttgcaa tctattccaa
     6181 ctgagattac agaggcagca aggattgatg gtgcgactag caagcaagtt ttctggaaca
     6241 ttgaattgcc ttacttgcta ccaagtgtct ctatagtctt tatcctagcc ctaaaaggtg
     6301 ggctgactgc ctttgaccaa gtctttgcca tgaccggtgg tggtccaaac aatgccacaa
     6361 cctcacttgg gctcttggtt tataactatg cctttaaaaa caaccaattc ggttatgcca
     6421 atgccattgc cgtaatcttg ttcttcttaa ttgtagtgat ttcgatcatc caattgagag
     6481 tatctaagaa atttgaaatt taagaggaga agcatgatga aacaagatga aagaaaagcc
     6541 ctgattggca aatacattct attgattcta ggatcggttc tgattttagt gccgctcctt
     6601 gctaccctct ttagttcctt caaacccact aaggatattg tagataattt ctttggtttt
     6661 ccaaccaact tcacatggga caactttagc cgtctcttag ctgatgggat tggaggctat
     6721 tattggaact ctgtcgtcat cactgtcttg tctttacttg cagtaatgat ctttatccct
     6781 atggcagcct actccatcgc tcgcaatatg agtaaaagaa aagcctttac catcatgtat
     6841 accctcttaa tcctcggaat cttcgtacct ttccaagtca tcatgattcc gattacggtt
     6901 atgatgagta aactcggttt ggctaatacc tttggtttga tcttgctcta cttgacctat
     6961 gcgattccac agaccctctt tctctatgtt ggctatatca aaatctcgat tccagaaagt
     7021 ctggatgaag cagcagagat cgatggggct aatcaattta caacctattt ccgcatcatc
     7081 ttcccaatga tgaaaccgat gcatgcgaca accatgatca tcaatgccct ttggttctgg
     7141 aatgacttca tgttgccact ccttgtcttg aaccgggatt ccaaaatgtg gactctgcct
     7201 ttgttccaat acaactacgc aggccaatat ttcaacgact acggaccaag ctttgcctct
     7261 tacgtggtcg gcattatcag tatcaccatt gtctatctct tcttccaacg ccatatcatt
     7321 tcaggaatga gcaacggggc agtgaagtaa tactcaatga aaatcaaaga gcaaactagg
     7381 aagctagccg caggctgtac ttgagtacgg taaggtgaag ctgacgtggt ttgaagagat
     7441 tttcgaatag tataagaaga gctcatggaa tctatagtct ttgacacaga ggaagagttc
     7501 agcttgttga taattctatg tagaaaacaa gaaagtagta ctttgtttat cacagtctat
     7561 attagtacga gtttgatgat aaatagagat ttaaaatgaa ttttatttat gaagccagat
     7621 catatgagac ttggcttcaa ttagaaaaag gagagtaatg atgccaattc aaaataaaac
     7681 catgttgatt acctattctg atagccttgg aaataatctt aaagacttat atgataattt
     7741 ggaagagcat tttcgagatg ctattggagg agttcacctt ttaccatttt tcccatcaac
     7801 aggtgatcgt ggatttgcgc cagttgacta cgacgaagtg gactcagctt ttggtgattg
     7861 ggaggatgtt aagcgtttag gtgagagata ttatcttatg tttgatttta tgattaatca
     7921 tatttctcgt caatccaagt attataagga ctatcaagaa aaacatgaag ccagtgaatt
     7981 taaagctctc tttttaaact gggataagtt ttggccagaa aaccgtccga cacagtctga
     8041 tgtagattta atttacaagc gtaaggatcg tgcaccaaag caagagattg tgtttgaaga
     8101 tggttcagtg gaacatttgt ggaatacctt tggtgaggag cagattgatc ttgatgtgac
     8161 caaagaagta actatggaat ttatccgtaa gaccattcag cacttggcaa gtaatgggtg
     8221 tgatttgatt cgtctagatg cctttgctta tgcagtgaag aaattggata ctaatgattt
     8281 ctttgtggaa ccagatattt gggatttatt ggacaaagtt cgagatatcg ctgctgagta
     8341 tgggacagag cttttacctg agattcatga acactattcg attcagttta aaatagcaga
     8401 ccatgattac tatgtttatg attttgctct tccaatggtg acactttata ctctttacag
     8461 ttccagaaca gagcgtttgg ctaagtggtt aaagatgagc ccgatgaagc aatttacgac
     8521 gctagatacc catgatggga ttggagtagt agatgtcaag gatatcctga ccgatgagga
     8581 gattgactat gcttcaaatg aactctataa ggttggagcc aatgtcaaac gtaagtactc
     8641 tagtgccgag tataacaact tagatatcta ccaaatcaat tcaacctact attcagcgct
     8701 tggagatgat gatgtcaagt attttctcgc tcgtctaatt caagcttttg ccccaggtat
     8761 tcctcaggtt tactatgtgg gtctattagc aggcaagaat gacttgaaat tattagaaga
     8821 aactaaagaa ggtcgaaata ttaatcgtca ttactatagc aacgaggaaa tagcaaaaga
     8881 agtgcaacga cctgttgtga aggcccttct caatctattt tctttccgta accgttcaga
     8941 agcctttgat ctagaaggga ctactgagat agagacacca acagctcaca gcattgtaat
     9001 caaacgtcaa aataaagata agtccgtaac agcagtagta gaaattgatt tgcaaaatca
     9061 gacttatcgg gtaattgaga atggagttga agtatcattt tgaagccttg atatggtgga
     9121 taaaataggg tttttatttt ggaaaacgtt tcctttgttt tcaaattgct aaaaaagtgg
     9181 tacaatatag gatagcttac tattatctga atcagctgat ttggagagaa aggattcatt
     9241 ttgaaatcaa taggctttat tgaaaagctg aaggggttgt ctagtaaaga gctgatttta
     9301 ttgggaatta tcctaagtat ctttttaccc ttttatcttt ttgtagttgt actctgttta
     9361 tatattatca gtttgatttt tacaggagac atgaaaagta ttcttcagaa aatgggggag
     9421 catccgatgc tgcttctttt tcttagctat agtactgtta tatccattct tgcacaaaat
     9481 tggatgggtc ttgtggcttc agtaggaatg tttctattta ctattttctt tttgcactat
     9541 cagtcgattt tatcccataa attctttcga ttgattttgc agttcgtctt gtttggtagt
     9601 gtcttgtcag ctgcttttgc cagtttagaa catttccaaa ttgtgaagaa atttaactat
     9661 gcttttcttt cacccaatat gcaggtgtgg catcagaacc gggcagaagt gaccttcttt
     9721 aatcctaatt attatggaat tatttgttgt ttctgtatta tgattgcttt ctatctgttt
     9781 acaacgacca agttgaattg gttgaaagta ttctgtgtga ttgcaggctt tgttaatctc
     9841 tttggtttga actttactca aaatcgaact gcctttcctg ctattatcgc tggagcaatt
     9901 atctatctct ttacgactat taaaaactgg aaggcctttt ggcttagtat tggggtcttc
     9961 gcgattggtt tgagtttcct cttttctagt gatttgggag ttcgaatggg tactttagac
    10021 tcttctatgg aagaacgcat ttctatctgg gatgctggga tggccttgtt taagcaaaat
    10081 cctttttggg gtgaagggcc attgacctat atgaactctt atcctcggat acatgctcct
    10141 tatcatgaac atgcccacag tctttatatt gatacgattc tgagttacgg aattgtgggg
    10201 actattttat tagttttgtc ttctgttgct cctgttcgct tgatgatgga tatgagtcag
    10261 gagtcgggga aacgtccgat tatcggcctt tatctatctt tccttacagt ggttgctgtg
    10321 cacggaattt ttgacttggc tctcttctgg attcagtcag gctttatttt cttgctagtt
    10381 atgtgcagta ttccattgga gcatcgaatg ttggtatcgg acatgacgga ttaagtttta
    10441 taagtttgaa atcttctacc ttgggtagga gattttttat acgatgggca tgtcgtgcat
    10501 ctgaggtgta agtcctctgt agggctccac taccggtgaa tacaatagcg ctccccaagc
    10561 ctgactatcg tgaggtagcg gattaaaatg gtctggggat agatcgtttt aagtctgacg
    10621 caggaaataa gaattgtcag agaaagcaat agtgaaatcg taggctatga atagaaacgt
    10681 gatagcgagg agcatatagt ggataaggta gcgagaaatt ttaaagtata aaagatagtc
    10741 ttaatctata tatgtaaatc acaaaagtaa ttgaattcgg gataaggttg gtgtgaaaag
    10801 acatagtaaa ctgaatcttg aatactagaa tgatacttct acaatattgt tataatttaa
    10861 tttgaattcc aaaatcacat tgttccgtcc gtatttcatt ttactgtatg tcttcctaaa
    10921 ctccaaagtt tctgcgtcaa atttcctatt ttcactgtag tctttgacac ttcgaacgac
    10981 aatttgaatc atatattcaa aaaaaatgaa aaatttgtgc caacaagcct aaatattctg
    11041 aaaatttgtt tgatttttaa tggataatgt gatataatgg ttgtcaatct ataattcaca
    11101 taaacagagg agtagaaaat gaaaaaaaat cgtgtatttg ctacagcagg tcttgtttta
    11161 ttagcagcag gtgtacttgc agcatgcagt tcttcaaaat catctgattc atcagcccct
    11221 aaagcttatg gctatgttta tacagcagac ccagaaacct tggactacct gatttcaagt
    11281 aaaaatagta caacagtagt gacttcaaat gggattgatg gtttattcac taacgataat
    11341 tacggtaatc ttgctcctgc agttgcagag gattgggaag tctctaagga tggtttgacc
    11401 tacacttata agattcgtaa aggggttaaa tggtttacct ctgatggaga agaatatgca
    11461 gaggtgacgg ctaaagattt cgtgaacggt ttaaaacacg cagcagataa aaaatcagaa
    11521 gctatgtatt tagctgaaaa ttcggttaaa ggcttggcag attatctatc aggaacttca
    11581 acagattttt caacagttgg tgtcaaggcg gttgatgatt atacgttaca atacactttg
    11641 aaccagcctg aaccgttctg gaactctaag ttgacctatt ctattttctg gcctctgaat
    11701 gaagaattcg aaacatcaaa aggaagcgat tttgctaaac caacagatcc gacatccttg
    11761 ctttataatg gtccattctt gttgaaaggg ttgactgcaa aatcttctgt agagtttgta
    11821 aaaaatgagc aatattggga taaagaaaat gtccacctag atactatcaa tctagcttac
    11881 tatgatggat cagatcagga gtcgctagag cgtaacttca ctagtggagc ttatagttat
    11941 gcccgtcttt accctaccag ctccaactat tctaaggttg cagaagaata caaggacaat
    12001 atctattaca cacaatcagg ctctgggatt gctggtctgg gtgtgaatat tgatcgccaa
    12061 agttacaact atacttctaa aactacagat tcagagaaag tagctactaa gaaggcattg
    12121 cttaacaaag atttccgtca agccttgaat tttgctcttg atcgctcagc ttactcagct
    12181 caaatcaatg gtaaagatgg agcagcttta gcagttcgta atttatttgt aaaaccagac
    12241 tttgtttcag ctggtgagaa gacctttggt gatttagtcg ctgctcaact tcctgcttat
    12301 ggtgatgagt ggaaaggtgt gaatttagct gatgggcagg atggtttatt caatgctgac
    12361 aaggccaagg cagagtttgc gaaagctaag aaagctttag aagcagacgg cgttcagttt
    12421 cctattcatc tggacgttcc agtagaccaa gcatcaaaaa actatatatc tcgtattcag
    12481 tcctttaaac aatctgtaga aacagttctt ggtgttgaaa atgtcgttgt tgatattcaa
    12541 caaatgacaa gtgatgaatt ccttaatatt acttactatg ctgccaatgc ttcatctgag
    12601 gattgggatg tatcaggagg agtttcatgg gggccagact atcaagaccc atctacttac
    12661 ctggatattt taaaaacaac tagcagtgaa actacaaaaa catatttagg atttgataat
    12721 ccaaatagcc cttcagtagt tcaagttggt ttgaaagaat acgataaatt agttgatgaa
    12781 gctgccaaag agacaagcga cttgaatgtc cgttatgaaa aatatgcagc ggctcaagca
    12841 tggttgacag atagttcact ctttattcct gctatggctt cttctggtgc agcaccagtg
    12901 ctttcacgaa ttgttccatt tactggagct tctgcgcaaa caggctctaa ggggtcagat
    12961 gtttacttca aatatttgaa attacaagat aaagtggtga ctaaggaaga gtatgaaaaa
    13021 gctcgtgaaa aatggttgaa agaaaaagct gaatcaaatg agaaagctca aaaagaattg
    13081 gcaagtcatg tgaagtaaat aatttctaat agaactttct ctccatgagg agaaggttct
    13141 tttgggattt ttaaaggaaa taatatgaaa aaatatattt ttatgcgtgt tttgcggtca
    13201 ttggtttcga ttttcttagt aacgactttg acctacacga ttatctatac cttggttcct
    13261 cgaaaattga ttttcaagca ggatcctaac tataataaaa ttgcgacaac ggctgataaa
    13321 cgtgataact atgaaaatac tgtgtttgag cgtatgggct acattgagta ttacgatact
    13381 aaagagttgc aagaaaaggc aagtagcatg gattcttctg taacagtaga agcaaatgcg
    13441 accaataaag ctatttatga aaagtacatc aatcaattag gtcatggttg gactttggga
    13501 gaatttactg aaagtggtca attctatgct actcgtgaaa ttccaatttt tgaacgtgtt
    13561 tttcacttct atgctaactt gattgacatt gaccatacaa ataaaatcca agaccctgaa
    13621 aatccagact tgaaacgcta ccttcgtttt gaaaatgatc cagctatcgg atggtcattg
    13681 gtcggttcag gaactaaaca taaatatctc ttgtacttta acagtcagtt cccatttgtt
    13741 catcaaaact ttgtgaactt gaatttaggt gactcttacc caacctatgc taatacacca
    13801 gttcttcagg ttattactca aggtcaagga caaaccaaaa ctgcccaagt tcagttccca
    13861 acaggtaaga aaacgtcttc tgtaaatatt tactcaagaa cctacaagtc acctagtcag
    13921 gctgactctc gtgaagtagc tagctatggg aaagatgatc cttatacagc gactgaaagt
    13981 aattaccaat atccatctat gattgtcagc tctgctatta ctggtttgat tggtttggtt
    14041 cttgcctatg ctcttgccgt gccacttggt tcagccatgg ctcgtttcaa gaacacttgg
    14101 attgatagcc tctcaacagg gactttgacc ttcttgcttg ctcttccaac gattgccttg
    14161 gtttacatcg ttcgattgat tggatcatct attgcccttc cagattcatt ccctatcttg
    14221 ggagctggag attggcgttc ttacgtttta ccagcagtca tccttggttt gttgggtgct
    14281 cctgttacag ccatttggat tcgtcgttac atgattgact tgcaatctca agactttgtt
    14341 cgtttcgctc gtgcaaaagg tttgtctgaa aaagaaattt caaacaaaca catctttaaa
    14401 aatgccatgg ttccgctggt ttcaggaatt cctggtgcca ttattggggt tatcggtggt
    14461 gcaaccctta ctgaaacagt cttcgccttc ccaggtatgg gtaaaatgtt gattgactct
    14521 gtaaaagcat ctaataactc tatggtcgtt ggtcttgtct tcatctttac atgtatttct
    14581 atcttctcac gtcttttggg agatatttgg atgactatta ttgacccacg tattaaattg
    14641 actgagaaag gaggcaaata atgtctacaa tcgataaaga aaaatttcag tttgtaaaac
    14701 gtgacgattt tgcctctgaa actattgatg cgccagcata ttcttactgg aaatcagtgt
    14761 ttaaacaatt tatgaagaaa aaatcaactg tagtcatgtt gggaatcttg gtagccatca
    14821 ttttgataag tttcatctac ccaatgtttt ctaagtttga tttcaatgat gtcagcaagg
    14881 taaacgactt tagtgttcgt tatatcaagc caaatgcgga gcattggttc ggtactgaca
    14941 gtaacggtaa atcgctcttt gacggtgtct ggttcggagc tcgtaactcc atcctcattt
    15001 ctgtgattgc gacagtgatt aacttggtta tcggtgtttt tgtcggtggt atttggggta
    15061 tttcaaaatc agttgaccgt gtcatgatgg aagtttacaa cgtcatctca aacatcccac
    15121 ctcttttgat tgttattgtc ttgacttact caatcggagc tggattctgg aatctgattt
    15181 ttgccatgag cgtaacaaca tggattggta ttgccttcat gatccgtgtg caaatcttgc
    15241 gctatcgtga cttggaatac aacttggcgt cacgtacttt gggaacacca accttgaaga
    15301 ttgttgccaa aaatatcatg cctcaattgg tatctgttat tgtgacaacc atgactcaaa
    15361 tgcttccaag ctttatctca tacgaagcct tcttgtcttt cttcggtctt ggattaccga
    15421 ttacagtgcc aagtttgggt cgtttgattt cggattattc acaaaacgta acaaccaatg
    15481 cttacttgtt ctggattcca ttgacaaccc ttgtcttggt atccttgtcc cttttcgtag
    15541 ttggtcaaaa cttagcggat gctagtgatc cacgtacaca tagataggag tagaaatgac
    15601 aaaagaaaaa aatgtaattt tgactgctcg cgatattgtc gtggaatttg acgttcgtga
    15661 caaagtattg acagccattc gcggcgtttc ccttgaacta gttgaaggag aagtattagc
    15721 cttggtaggt gagtcaggat caggtaaatc tgttttgaca aagaccttca caggtatgct
    15781 cgaagaaaat ggtcgtattg cccaaggtag tattgactac cgtggtcagg acttgacagc
    15841 tttatcttct cacaaggagt gggaacaaat tcgtggtgct aagattgcga ctatcttcca
    15901 ggacccaatg actagtttgg accccattaa aacaattggt agtcagatta cagaagttat
    15961 tgtaaaacac caaggaaaaa cagctaaaga agcgaaagaa ttggccattg actacatgaa
    16021 taaggttggc attccagacg cagatagacg ttttaatgaa tacccattcc aatattctgg
    16081 aggaatgcgt caacgtatcg ttattgcgat tgcccttgcc tgccgacctg atgtcttgat
    16141 ctgtgatgag ccaacaactg ccttggatgt aactattcaa gctcagatta ttgatttgct
    16201 aaaatcttta caaaacgagt atcatttcac aacaatcttt attacccacg accttggtgt
    16261 ggtggcaagt attgcggata aggtagcggt tatgtatgca ggagaaatcg ttgagtatgg
    16321 aacggttgag gaagtcttct atgaccctca ccatccatat acatggagtc tcttgtctag
    16381 cttgcctcag cttgctgatg ataaagggga tctttactca atcccaggaa cacctccgtc
    16441 actttatact gacctgaaag gggatgcttt tgccttgcgt tctgactacg caatgcagat
    16501 tgacttcgaa caaaaagctc ctcaattctc agtatcagag acacattggg ctaaaacttg
    16561 gcttcttcat gaggatgctc caaaagtaga aaaaccagct gtgattgcaa atctccatga
    16621 taagatccgt gaaaaaatgg gatttgccca tctggctgac taggaggaag gaaatgtctg
    16681 aaaaattagt agaaatcaaa gatttagaaa tttccttcgg tgaaggaagt aagaagtttg
    16741 tcgcggttaa aaatgctaac ttctttatca acaagggaga aactttctcg cttgtaggtg
    16801 agtccggtag tgggaaaaca actattggtc gtgctatcat cggtctaaat gatacaagta
    16861 atggagatat catttttgat ggtcaaaaga ttaatggtaa gaaatcgcgt gaacaagctg
    16921 cggaattgat tcgtcgaatc cagatgattt tccaagaccc tgccgcaagt ttgaatgaac
    16981 gtgcgactgt tgattatatt atttctgaag gtctttacaa tcaccgttta tttaaggatg
    17041 aagaagaacg taaagagaaa gttcaaaata ttatccgtga agtaggtctt cttgctgagc
    17101 acttgactcg ttaccctcat gaattctcag gcggtcaacg tcaacgtatc ggtattgccc
    17161 gtgccttggt catgcaacca gactttgtta ttgcagatga gccaatttca gccttggacg
    17221 tttctgtacg tgcccaagtc ttgaacttgc tcaaaaaatt ccaaaaagag ctcggcctga
    17281 cctatctctt catcgcccat gacttgtcgg ttgttcgctt tatttcagat cgtatcgcag
    17341 ttatttacaa gggtgttatt gtagaggttg cagaaacaga agaattgttt aacaatccaa
    17401 ttcacccata tactcaagcc ttgctttcag cggtaccaat cccagatcca atcttggaac
    17461 gtaagaaggt cttgaaggtt tacgacccaa gtcaacacga ctatgagact gataagccgt
    17521 ctatggtaga aatccgtcca ggtcactatg tttgggcgaa ccaaaccgaa ttggcacgtt
    17581 atcaaaaagg actaaactag taatggtttt ataatttcca tgtcaatttt tatggaaatt
    17641 aggctctttg tcaactgtag tgggttgaag tcagctaagc ttgagaaagg acaaatttcg
    17701 tcctttcttt tttgatgttc aaagcgataa aaatccgttt tttgaagttt tcaaagtttc
    17761 gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt attggtcgct tccagtttgg
    17821 cattagaata gtgtagttga agggcgttga taatcttttc tttatctttg aggaaggttt
    17881 taaagacagt ctgaaaaata ggatga
//
LOCUS       DAVKXA010000046        16667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKXA010000046 DAVKXA010000000
VERSION     DAVKXA010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.046"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            608..829
                     /locus_tag="VW883_001646"
     CDS             608..829
                     /locus_tag="VW883_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0274752.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            1346..1585
                     /locus_tag="VW883_001647"
                     /pseudo
     CDS             1346..1585
                     /locus_tag="VW883_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1729..2958
                     /locus_tag="VW883_001648"
     CDS             1729..2958
                     /locus_tag="VW883_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0274753.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2978..5674
                     /gene="ppc"
                     /locus_tag="VW883_001649"
     CDS             2978..5674
                     /gene="ppc"
                     /locus_tag="VW883_001649"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0274754.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5757..5974
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6087..7091
                     /locus_tag="VW883_001650"
     CDS             6087..7091
                     /locus_tag="VW883_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0274755.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7160..8026
                     /locus_tag="VW883_001651"
     CDS             7160..8026
                     /locus_tag="VW883_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274756.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8023..8781
                     /locus_tag="VW883_001652"
     CDS             8023..8781
                     /locus_tag="VW883_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274757.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8871..10631
                     /gene="dnaG"
                     /locus_tag="VW883_001653"
     CDS             8871..10631
                     /gene="dnaG"
                     /locus_tag="VW883_001653"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0274758.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10634..11743
                     /gene="rpoD"
                     /locus_tag="VW883_001654"
     CDS             10634..11743
                     /gene="rpoD"
                     /locus_tag="VW883_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0274759.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11757..12086
                     /locus_tag="VW883_001655"
     CDS             11757..12086
                     /locus_tag="VW883_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0274760.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12201..13244
                     /gene="cpoA"
                     /locus_tag="VW883_001656"
     CDS             12201..13244
                     /gene="cpoA"
                     /locus_tag="VW883_001656"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0274761.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13260..14585
                     /locus_tag="VW883_001657"
     CDS             13260..14585
                     /locus_tag="VW883_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0274762.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14616..14792
                     /locus_tag="VW883_001658"
     CDS             14616..14792
                     /locus_tag="VW883_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0274763.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14851..14985
                     /locus_tag="VW883_001659"
     CDS             14851..14985
                     /locus_tag="VW883_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0274764.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15049..16359
                     /gene="obgE"
                     /locus_tag="VW883_001660"
     CDS             15049..16359
                     /gene="obgE"
                     /locus_tag="VW883_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0274765.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16369..16527
                     /locus_tag="VW883_001661"
     CDS             16369..16527
                     /locus_tag="VW883_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274766.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         5130 a         2903 c         3680 g         4954 t
ORIGIN      
        1 ttatgggatt tgaattttcc cttcttccaa aactaataaa attgaaagaa caaaatctag
       61 tttaaatgtt gctcgaaaat taaataattg aatacgatta acaatgaaac aatacaacgt
      121 gagtcatgac ttcaaagtaa ttgattttat gattctggtt tcttacgctt aattaagcaa
      181 gttgtattca ctttatcaaa ttgttattac tctaaaaagc gtctaacagc tatagagtgt
      241 ctgtttgctt ctctttactt ttattttaaa taattcatta accttccgta agtgcccaat
      301 aataaggtgt gttgaagaag tctgagataa aatagttctc agtcacaaaa aaagctatag
      361 attcccattg gtgaacagct ccctgtcaag tagacagtaa aataatataa aatcttaagc
      421 gacctgattc ctgaattcca gtggagtcag gttgtttttt aaccgtcttt cttaatattg
      481 tctcacctat aatagatatg cttatgagat atgtttaata aattaatttt agttcaaaat
      541 gtccagttag gacactttga atgatttctt agttttatat attatacttt tctcaggaga
      601 aagctagatg tacagacgtt tgagagattt gagggaagat cacgatttga cccaaaaaca
      661 aatagctaaa atactttcgt ttacaaactc agcttatgct aaaattgaac ggggtgagca
      721 tacgttaaca gcagatgtat tggtaactct ctcaaacttt tacgatgtca gtacagacta
      781 cctattggaa ttgacagatt ttcctgataa aattcgcttt agaaaataat ctcctcaatt
      841 tcatagagtg tgaaaatgag gagatttttt atttgttctt tgaaaattaa atagtccaaa
      901 atggtacttt cctcatttgt ggagcaaatt tgaatggctc gccatgataa gagcgatttt
      961 aaaaccatca ataaaataga gcgatacttt atatgccatg atacaaatga tatacaatga
     1021 tacttctgac cgttcaggct gccatcgtaa aagagcagca agtgaaattc ttatgatgac
     1081 ttcatcagtc atgccacgtt gaatgtgtga gtttgttaga gaaacgcaat taatcctcaa
     1141 aaggttcccc gaaccttttg agttccacag acgcatcacg tggagtgtgt aagcttgttg
     1201 ctaaaagcgt aaaaaccttg gaacgaaagg aataatagac ttcctgcgaa acaaaaatac
     1261 aatacaataa aactatggat gatgaagcaa gtaaacaatt aagcgatagc cgtttcaaga
     1321 gccttgtagg tgttcagcgc acgagatgtt agctgtgtta aaaacagctt atcaacgcaa
     1381 cgtaaacgcg caaaaggtgg acgaaaaacc aaattaagcc tagacgatct cctcatggta
     1441 actattcaat acatgcgaga atagcgcact tatgaacaaa ttgcggctga ttttggcatt
     1501 cacgaaagca acataattag tcggaggtca atggattgaa gcaactctta ttcaaaatgg
     1561 ttttacgatt tcaaattctg ccttaattct gtaaaaacag taaaattcga aggattgtaa
     1621 ggtaagagtt tttttctttc tgaaaaaatg gtataatagc aatcaaaact agaaaataaa
     1681 acggaatttg gaacagattt gtctgtatcc tagtagagtg gtgatactat gaagattagt
     1741 aagaggcact tattaaatta ttccatcttg attccctact tgcttttatc tattttgggc
     1801 ttgattgtgg tctattcgac caccagtgct attttaattg aagaaggcaa gagcgccttg
     1861 cagttggttc gaaaccaagg aatcttttgg attgttagtt tgatactgat tgccttaatt
     1921 tataaattga gactagattt tttgagaaat gagcgactaa tcattttagt tatattaata
     1981 gaaatgcttt tattgttctt ggctcgtttt attggtattt cagtaaacgg ggcatacggt
     2041 tggatttcgg ttgcaggagt aactattcag ccagctgagt acttaaaaat cattattatt
     2101 tggtatttag ctcaccgatt ctccaaacag caagaagaaa tagctactta tgattttcaa
     2161 gttttgactc aaaatcaatg gcttccccgt gcttttaatg attggcgatt cgttctccta
     2221 gttctgattg gaagtttggg aattttccct gatttaggaa atgcgactat tttagtcttg
     2281 gtttccttga ttatgtatac agttagtgga atcgcttatc gctggttttc aaccattctg
     2341 gcgctcgtat ctgccgcttc tgtctttgtc ttgaccacta tcagcctaat cggtgttgag
     2401 accttttcaa aaattccagt atttggctat gtagccaaac gctttagtgc cttttttaat
     2461 ccttttgccg atcgtgctga tgcaggtcac cagttagcta attcttattt tgccatggtc
     2521 aatggtggtt ggtttggtct aggtcttgga aactcgattg aaaaacgagg ttatttgcca
     2581 gaagctcata cagactttgt cttttctatc gtgattgaag aatttggctt tgttggtgcc
     2641 agtcttattt tagctctctt gtttttcatg attttgcgga ttatcttggt cggtattcga
     2701 gcggagaatc ctttcaatgc catggttgca ctcggtgtcg gagggatgat gttggttcag
     2761 gtatttgtca atatcggagg gatttcgggc ttgattccat ctacaggagt aaccttcccc
     2821 ttcttatccc agggtggaaa tagtcttcta gtcttatcag tggcagtagc ctttgtctta
     2881 aatattgatg ccagtgaaaa acgcgctaag ttgtaccgag aattggaaaa tcaaccaatg
     2941 aaccttctgt tgaagtagga taaagaaagg atagtttatg tctcttcaaa aattagaaaa
     3001 ttctagtaat aaaagtgttg tgcaagaaga agtcttgatt ctaacagaat tactggaaga
     3061 tattactaaa aatatgcttg ccccagagac ctttgaaaaa ataatacagt tgaaagaatt
     3121 atcaacgcag gaagattatc aaggtctaaa ccgtctagtg actagcttat caaatgatga
     3181 aatggtctat atttcacgct atttctctat cttgcctctt ttgattaata tttcagagga
     3241 tgtggattta gcttatgaaa tcaatcatca aaataatatt gatcaggact atttaggtaa
     3301 attatctaca acgattaaat tggtagcaga aaaggaaaat gccgttgaga tcctagaaca
     3361 cttgaatgtt gttccggttt tgacagccca tccaacacaa gtgcaacgca aaagtatgtt
     3421 ggatttaaca aatcatattc atagtctttt gcgtaaatac cgtgatgtta agttggggtt
     3481 gatcaataaa gataaatggt acaatgattt gcgtcgttac atcgaaatta tcatgcagac
     3541 agacatgatt cgtgagaaaa aattaaaagt gactaacgaa atcacgaatg ctatggaata
     3601 ttataacagc tcctttttga aagctgtacc tcatttgacg acggagtata agcgcttagc
     3661 gcaagcgcat ggtctgaatt taaaacaggc taaaccaatc accatgggta tgtggatagg
     3721 tggtgaccgt gatggaaatc catttgttac agcaaagacc ttgaagcagt ctgcactcac
     3781 tcagtgtgaa gtcatcatga actactatga taaaaagatt taccaacttt atcgtgaatt
     3841 ttctctttca actagcattg tcaacgtcag caaacaagtc agagaaatgg ctcgtcaatc
     3901 caaggataac tcgatttacc gcgaaaaaga gctttaccgt cgtgccttgt ttgatattca
     3961 atcaaaaatt caggcaacta aaacctatct gattgaggat gaagaagttg ggactcgtta
     4021 tgaaaccgcc aatgatttct acaaggattt gattgccatt cgagattctc tactagaaaa
     4081 taagggcgag tccttgattt caggtgattt tgtggaatta ttgcaggcag tagagatatt
     4141 tggtttttac ttagcatcaa ttgatatgcg acaagactct agcgtctatg aagcctgtgt
     4201 ggcagaactc ttgaaatcag caggaattca ttctcgttat agcgagttga gcgaagaaga
     4261 aaagtgtgac cttctcttga aagaattaga agaagatccc cgaattcttt ctgcgactca
     4321 cgcagaaaaa tcagaattat tagcaaaaga actagctatt tttaagacgg ctcgtgtttt
     4381 gaaagataag ttgggagatg atgtcatccg tcagaccatc atttcacatg caaccagcct
     4441 ttctgatatg ctagaattag ctattctgtt aaaagaagta ggactggtgg atacggaaag
     4501 ggcgcgtgtt cagattgttc ccctttttga aacaattgaa gacttggatc attcagagga
     4561 aacaatgaga aaatatcttt ctcttagcct tgccaaaaaa tggattgact cacgaaataa
     4621 ctaccaagaa atcatgcttg gctactctga cagtaataaa gatggcggtt acttgtcatc
     4681 atgttggacc ctctacaagg ctcaacaaca attgactgct attggagatg aatttggcgt
     4741 taaggttacc ttcttccatg gtcgtggtgg tactgtcggt cgtggtggtg ggccaaccta
     4801 tgaagccatt acatctcaac cgctcaagtc tatcaaggat cgtatccgct tgacggagca
     4861 gggtgaagta attgggaata aatacggtaa caaagacgcc gcttactata accttgaaat
     4921 gctagtatcg gcagctatta accgtatgat tactcagaag aagagcgata ccaatacccc
     4981 aaatcgttat gaagccatta tggatcaagt agtggaccgt agttacgata tctaccgtga
     5041 tttggtcttt ggtaatgagc atttctatga ttatttcttc gagtcaagtc caatcaaggc
     5101 tatttcaagt tttaatattg gttctcgtcc agccgctcgt aagactatta ctgaaatcgg
     5161 tggattgcgt gctatccctt gggtattctc atggtcacag agtcgtgtta tgttccctgg
     5221 atggtacggg gttggttcaa gcttcaagga atttatcaat aaaaatccag agaatattgc
     5281 tatcttacga gatatgtacc aaaattggcc tttcttccaa tcgcttcttt caaatgttga
     5341 tatggttttg tcaaaatcaa atatgaatat tgcttttgaa tatgctaaac tttgtgaaga
     5401 cgagcaagtt aaggccatct atgagactat tttaaatgaa tggcaagtta ctaagaacgt
     5461 tatcttggct attgaaggac atgacgaact cttagctgac aatccatatc taaaagctag
     5521 tctggattac cgtatgcctt actttaatat tctcaactat attcagttag agttgattaa
     5581 acgccaacgt cgtggagaat tgtccagtga tcaagaacga ttgattcata tcaccatcaa
     5641 cggaattgcg acaggattgc gtaattcagg ttgataattt tcaagagtga atgctaaaag
     5701 tgaatatcaa aaaaattcta atagactatt gacaagtagt ttaaaaatga tataatttaa
     5761 ccattcagaa aagtaatcat acaaactttt tagagagtct gtggtagctg aaaacagata
     5821 agtggcaatg atgaaaattg ggctgaatgc tatttagaat ttgaaattat aaaaattcgg
     5881 taagcacacc ttacagtgca tctcgttatt gcgagactga gcgataggga aattccctat
     5941 aattgaggtg gtaccgcgca tcgacgtcct cacacaagtt ttttgtgtga ggattttttt
     6001 gatggaggtt agtatggaaa gaaaacgatg gcgtcgcttg tttagataag tgaaatatgt
     6061 taaaggaaat aaaaaggaga aacagaatga aaaataaacg tttaattgga attattgctg
     6121 cattagcagt cttagtagca ggaagcttga tttattcttc aatgaataaa tcagaagctc
     6181 agaataataa ggatgagaag aaaataacca agattggtgt gcttcaattt gtgagccatc
     6241 catcccttga tttgatttat aaagggatcc aagatggact tgcagaagaa ggatataaag
     6301 atgatcaagt taaaattgat tttatgaact cagaaggtga ccaaagtaag gttgcgacaa
     6361 tgagtaaaca attggttgca aatgggaatg accttgtggt tggtatcgca acaccagcag
     6421 cccaagggtt ggctagtgca acaaaagacc taccggttat catggccgct attacagacc
     6481 caattggtgc taacttggtt aaagatttga aaaaaccagg tggcaacatt acaggggtat
     6541 ctgaccacaa tccagctcaa caacaagttg aactcatcaa ggctctgaca ccgaatgtga
     6601 aaacaatcgg agctctttac tcaagtagcg aagacaattc aaaaacacag gtcgaagaat
     6661 ttaaggctta tgctgaaaaa gcaggtctga cagtggaaac atttgcagtt ccttcaacaa
     6721 atgaaattgc ctcaactgtc actgttatga ctagcaaggt agatgctatt tgggttccaa
     6781 ttgataacac cattgcatca ggatttccaa cggttgtctc tagcaatcaa agttctaaga
     6841 aaccaattta tcccagtgcg acagctatgg tagaagtagg tggtttggca tcagttgtaa
     6901 ttgaccaaca tgaccttggt gtggcaacag gtaaaatgat tgtgcaagtc ttgaaaggtg
     6961 caaaaccagc cgatacccca gtcaatgtct tttcaactgg taagtcagtc atcaataaaa
     7021 aaatagcaca agaactaggt attactattc ctgagtctgt tctcaaagaa gcaggacaag
     7081 tcatcgaata aataaggtag ggaggaggag actcttccca ttttttaaaa agatgaatat
     7141 agaaaggatt aaataaaata tgattgtttc cattatttct caaggatttg tctgggctat
     7201 tctaggtctg ggaatcttta tgacatttag gattttaaac tttccagata tgacgacaga
     7261 aggttccttc cctcttgggg gagctgttgc tgtcactttg ataaccaaag gcgtgaaccc
     7321 atttttagcg acacttgttg ctgtaggagc aggttgtttg gctggaatgg cagcaggcct
     7381 tctttataca aaagggaaga tcccaacctt gctctcaggg attttggtga tgacttcttg
     7441 tcactcaatc atgctcttga ttatgggacg tgcgaattta ggcctgcttg gaaccaagca
     7501 aattcaggat gttttgcctt ttgattcgga tttgaatcaa ctcttgacag gtctcatctt
     7561 tgtgagtatt gttattgctc tcatgctctt tttcttggac actaaactcg gacaagccta
     7621 tattgctaca ggggataatc ctgatatggc tagaagtttc gggattcata ctggacgcat
     7681 ggagctcatg ggcttggtct tatcaaatgg tgtgattgcc cttgcaggtg ccctcattgc
     7741 tcagcaagaa ggctatgccg atgtgtctcg agggatcggg gttatcgttg tggggcttgc
     7801 aagtttgatt attggagaag ttattttcaa gagtttgagc ttggcagagc gtttggttac
     7861 tatcgttgta ggttctatcg cttatcaatt tttagtgtgg gcagttatcg cacttggctt
     7921 taatacaagt taccttcgtt tatacagtgc cttgatttta gcagtctgcc tcatgattcc
     7981 aacatttaag caaacaatct tgaaaggagc caagttaagc aaatgacagc aattgtagaa
     8041 ttaaaaaatg caaccaaaat cgttaaaaat ggctttgatg aagaaaagat tattttaaat
     8101 gatgtttcct tagaaatttt tgaacgggac tttatcacga ttttgggcgg aaatggtgct
     8161 ggaaaatcaa ccctctttaa cactatagca gggaccttat cactaactag tggaactatc
     8221 cgtattttag gtgaagaact cactaagttt tcacccgaga agcgtgccaa gtacctgtct
     8281 cgtgtcttcc aagatccaaa gatggggaca gctccccgta tgacggtcgc tgaaaatctt
     8341 ttaatcgcca agtttcgtgg tgaaaagcgt ggattgttac cacgacgctt gactagctat
     8401 aaggatgaat ttcaggcaac cattgaaaaa gtaggaaatg gtcttgagaa acacttgaat
     8461 acaccgattg agttcttatc aggtggacaa agacaggctt tgagtctctt gatggcaacc
     8521 ttgaagcgac ctgaattact cctgttagat gagcatactg ctgccctgga tccaaagact
     8581 agtgttgctt tgatggaatt gacagatgaa tttgttaaga aagatcagct aacagccctt
     8641 atgattactc atcatatgga agatgctctc aaatacggca atcgcttgat tgtcatgaaa
     8701 gaaggacgga ttatccaaga tttaaaccaa gaagaaaaag caaaaatgaa aatctctgat
     8761 tattatcaac tctttgaata aagtagggaa aatgagtgaa atggtttact ttttttctga
     8821 aataaagtat actatataaa gtaaactatg ataacatgga ggtattgtgt atggttgaca
     8881 aacaagtcat tgaagaaatc aaaaacaatg ccaacattgt ggaagtcata ggagatgtga
     8941 tttctttaca aaaggcagga cggaactatc tagggctctg tccttttcat ggtgaaaaaa
     9001 caccttcttt caacgttgta gaggacaagc agttttacca ctgttttggt tgtggtcgct
     9061 caggtgatgt ctttaaattc atcgaggagt accaaggggt tacctttatg gaggctgtcc
     9121 aaatcttagg tcagcgtgtc gggattgagg ttgaaaaacc gctttatagt gaacagaagc
     9181 cagcctcgcc tcaccaagct ctttatgata tgcacgaaga tgcggctaaa ttttaccatg
     9241 ctattctcat gacaacgact atgggcgaag aggccagaaa ttacctttat cagcggggtt
     9301 tgacagatga agtgcttaaa catttttgga ttggtttagc acctccagaa cgaaactatc
     9361 tctatcaacg tttgtctgat cagtatcgtg aagaagattt actggattca ggcctgtttt
     9421 atctctcgga tgccaatcaa tttgtagaca cctttcacaa tcgcattatg tttcccctga
     9481 caaatgacca aggaaaggtc attgccttct caggtcgtat ctggcaaaaa acagattcac
     9541 aaacttctaa gtataaaaac agccgatcga ctgcaatttt taacaaaagt tacgaattat
     9601 atcatatgga tagggcaaaa aaatcttctg gaaaaactag tgagatttac ctgatggaag
     9661 gattcatgga tgttattgca gcctatcggg ctggaatcga aaatgctgtg gcgtcgatgg
     9721 gaacggcctt gagtcgagag catgttgagc atctgaaaag gttaaccaag aaattggttc
     9781 ttgtttacga tggagataag gctgggcaag ccgcgatatt gaaagcattg gatgaaattg
     9841 gtgatatgcc tgtgcaaatc gttagcatgc ctgataactt ggatcctgat gagtatctac
     9901 aaaaaaatgg tccagaagac ttggcctatc tattaacgaa aactcgtatt agtccgattg
     9961 agttctacat tcatcagtac aaacctgaaa acagtgaaaa tctgcaggct cagattgagt
    10021 ttattgaaaa aatagctccc ttgattgttc aagaaaagtc catcgctgct caaaacagct
    10081 atattcatat tttagctgac agtctggcgt cctttgatta tgcccagatt gagcagattg
    10141 ttaatgagag tcgtcaggtg caaaggcaga atcgcatgga aggaatttcc agaccgacgc
    10201 caatcaccat gcctatcacc aagcagttat cggctattat gagggcagaa gcccatctac
    10261 tctatcggat gatggaatcc cctcttgttt tgaacgatta ccgtttgcga gaagactttg
    10321 catttgctac acctgaattt caggtcttat atgacttgct tggccagtat ggaaatcttc
    10381 ctccagaagt tttagcagag cagacagagg aagttgaaag agcttggtac caagttttag
    10441 ctcaggattt gcctgctgag atatcgccgc aggaacttag tgaagtagag atgactcgaa
    10501 acaaggctct cttgaatcag gacaatatga gaatcaaaaa gaaggtgcag gaagctagcc
    10561 atgtaggaga tacagataca gccctagaag aattggaacg tttaatttcc caaaagagaa
    10621 gaatggagta ataatggcaa caaaacaaaa agaagtaaca acatttgacg tacaggtagc
    10681 agaatttatc cgtaatcata agcaaaaagg gacagcaaca gatgatgaaa tcaatgcaag
    10741 tctggttatt ccttttacct tggacgctga tgggattgaa gatctcttgc aacggattca
    10801 ggatgcaggc atttctatca cagataacga aggaaatcca agtgcgcgtg ttcttagcaa
    10861 tgaagaagaa ccagaactca gcgatgagga cttgattggg tcaacttctg ctaaggtcaa
    10921 tgaccctgtc cgtatgtact tgaaagaaat aggggtcgtt cctctcttga ccaatgaaga
    10981 ggagaaagag ttggcactgg ctgttgaagc tggcgatatc gaagccaaac aacgtcttgc
    11041 ggaagccaat cttcgtttgg ttgtttctat tgccaaacgc tatgtcggtc gtggcatgca
    11101 gttccttgac ttgattcaag aaggaaatat gggcttgatg aaggcggttg acaagtttga
    11161 ctattctaaa gggttcaagt tttcaactta tgcaacttgg tggattcgtc aggctatcac
    11221 tcgtgctatt gcggatcaag ctcgtaccat ccgtatccca gttcacatgg ttgaaactat
    11281 caataaattg gttcgtgaac agcggaatct ccttcaagaa ttggggcaag atccgacacc
    11341 agaacagatt gctgaacgaa tggatatgac acctgataag gttcgtgaaa tcttgaagat
    11401 tgcccaagaa ccagtatctc ttgaaactcc tatcggtgaa gaggacgata gccaccttgg
    11461 agactttatc gaagatgaag tgattgaaaa tccagtggat tatacgactc gtatcgtctt
    11521 gcgtgagcaa ttggatgaaa tcttagatac tcttacagac cgtgaagaaa atgttctgcg
    11581 tctacgtttt ggactagatg atggaaaaat gcgcacactt gaagatgtgg ggaaagtctt
    11641 taacgtaact cgtgagcgta tccgtcagat tgaagcaaag gctttgagaa aactacgcca
    11701 accaagccgc agcaaaccgc ttcgtgattt tattgaagac taagagtgag gaaaatatgg
    11761 cttatacaga agagcaaatt gaaaacatca aaacacggat tttaacagcc ttggaagaag
    11821 tcatcgaccc tgagttggga atcgatattg tcaatcttgg tttgatctat gagattcgtt
    11881 ttgacggtga cacagggcaa acagagattg acatgacttt gacaactatg ggttgtccct
    11941 tagcagacct tttgacagac cagatttatg atgctatgat agaggttcca gaagtaacgg
    12001 atactgaggt taaattagtc tggtatccag cctggacagt tgaaaaaatg agtcgctatg
    12061 cccgcattgc tctaggcatt aagtaaacat ataaaagcat gtgagagact gttggaaaag
    12121 cgaggaaatt tcccctcttt tcctctagtc tctcctttct tttgctgatt ttattcaaag
    12181 aaaatgatat aatagtagtt atggagaaaa agaaattacg catcaatatg ttgagttcaa
    12241 gtgagaaagt agcaggacag ggagtttcag gtgcttaccg tgaattagtt cgtcttcttc
    12301 accgtgctgc caaggaccaa ttgattgtta cagaaaatct tccaatcgag gcagatgtga
    12361 ctcactttca tacgattgat tttccctatt atttatcaac cttccaaaag aaacgctcag
    12421 ggagaaagat tggctatgtg catttcttgc cagctacact tgaaggaagt ttgaaaattc
    12481 catttttctt aaagggaatt gtgaaacgct atgtattttc tttttacaac cggatggagc
    12541 acttggttgt ggtcaatcct atgtttattg aggatttggt agcagctggt attccacgtg
    12601 aaaaagtgac ctatattcct aactttgtca acaaggaaaa atggcatcct ctaccacaag
    12661 aagaggtagt cagactgcgc acagatcttg gtcttagtga caatcagttt atcgtagtag
    12721 gtgctgggca agttcagaaa cgtaaaggga ttgatgactt tatccgtctg gctgaggaat
    12781 tgcctcagat tacctttatc tgggctggtg gcttctcttt tggtggtatg acagatggtt
    12841 atgaacacta taagaaaatt atggaaaatc cccctaaaaa tttgattttt ccaggcattg
    12901 tatcgccaga gcggatgcgc gaattgtatg ctctagcgga tcttttcttg ttgcctagtt
    12961 acaatgagct ctttcctatg actattttag aagctgcgag ttgtgaggct cctattatgt
    13021 tgcgtgattt agatctctat aaggtgattt tggagggaaa ttatcgggcg acagcgggta
    13081 gagaagagat gaaagaggct attttggaat atcaagcaaa tcctgctgtc ttaaaagatc
    13141 tcaaagaaaa ggctaagaat atttccagag agtattctga agagcatctg ttacaaatct
    13201 ggttggactt ttatgagaaa caagccgctt tagggagaaa gtaaaaagtg aggtaatcta
    13261 tgcgaattgg tttatttaca gatacctatt ttcctcaggt ttctggtgtt gcgaccagta
    13321 ttcgaacctt gaaaacagaa cttgaaaagc agggacatgc tgtttttatc tttacgacga
    13381 cagataagga tgtcaatcgc tacgaagatt ggcaaattat ccgcattcca agtgttcctt
    13441 tctttgcttt taaggatcgt cgctttgcct accgaggttt tagcaaggca cttgaaattg
    13501 ctaaacagta tcagctagat attatccata ctcagacaga attttctctt ggcctgttgg
    13561 ggatttggat tgcgcgtgaa ttgaaaattc cagtcatcca tacctatcac acccagtatg
    13621 aagactatgt ccattatatt gctaagggga tattgatccg gcctagtatg gtcaagtatc
    13681 tggttagagg tttcctgcat gatgtggatg gggttatttg ccctagtgag attgtccgtg
    13741 acttgctatc tgattataag gtcaaggttg aaaaacgggt cattcctact gggattgaat
    13801 tagccaagtt tgagcgtccg gaaatcaagc aggaaaattt gaaagaactg cgtagtaaac
    13861 tagggattca agatggtgaa aagacgttgc ttagtctttc gagaatctcc tatgaaaaaa
    13921 atattcaagc agttttagca gcctttgctg atgttctgaa agaggaagac aaggttaaac
    13981 tggtagtagc tggggatggc ccttatctga atgacctcaa agagcaagcc cagaacctag
    14041 agattcaaga ctcagtcatc tttacaggga tgattgctcc tagtgagacg gctctttact
    14101 ataaagcggc ggatttcttc atttcggcat cgacaagcga aacgcaaggt ttgacctact
    14161 tggaaagctt agccagtgga acacctgtca ttgctcacgg aaatccttat ttgaacaacc
    14221 tcatcagtga taaaatgttt ggagccttgt actatggaga acatgatttg gctggtgcta
    14281 ttttggaagc cctgattgca acaccagaca tgaacgagca taccttatca gagaaattgt
    14341 atgagatttc agctgagaac tttgggaaac gagtgcatga gttttatctg gatgccatta
    14401 tttcaaataa cttccagaaa gatttggcta aagatgatac ggtcagtcag cgtatcttta
    14461 ggacagtttt gtatcttccg caacaggtgg ttgctgtacc tgtaaaagga tctagacgca
    14521 tgttgaaggc ttcaaaaaca cagttgatca gtatgagaga ctattggaaa gaccatgaag
    14581 aatagaaaga ggaacagcta tgaaaaaaac aattaatgag aagcggtcgt gataaaaaga
    14641 ttgcgggtgt ttgtgctggg gtggcccatt atctggatat ggatccgact atcgttcaag
    14701 tcatttgggg tgttcttact tgctgttacg gagctggaat tgtagcttac attattttat
    14761 ggattatcgc accagtagca actgactatt gaaaactagc tcaattcatg ctaagataat
    14821 agaaaataga atgtaacgaa ggagagaaaa atggcatttg gagataatgg aaatcgtaaa
    14881 aaaactatgt ttgagaaaat aaccttgttt atcgtgatta tcatgctagt agcaagttta
    14941 ttgggaattt ttgcaactgc aattggtgcc ctcagtaatc tataaaatag attcaagaaa
    15001 atttagtgac tgggatttcc cagccctttt ttaaagtgag aagaaataat gagtatgttt
    15061 ttagatacag ctaagattaa ggtcaaggct ggtaatggtg gcgatggtat ggttgccttt
    15121 cgtcgtgaaa aatatgtccc taatggaggc ccttggggtg gtgatggtgg tcgtggaggc
    15181 aatgtggtct tcgttgtaga cgaaggacta cgtaccttga tggatttccg ctacaatcgt
    15241 catttcaagg ctgattctgg tgaaaaaggg atgaccaaag ggatgcatgg tcgtggtgct
    15301 gaggacctta gagttcgagt accacaaggt acgactgttc gtgatgcgga gactggcaag
    15361 gttttaacag atttgattga acatgggcaa gaatttatcg ttgcccacgg tggtcgtggt
    15421 ggacgtggaa atattcgttt cgcgacacca aaaaatcctg caccggaaat ctctgaaaat
    15481 ggagaaccag gtcaggaacg tgagttacaa ttggaactaa aaatcttggc agatgtcggt
    15541 ttagtaggat tcccatctgt agggaagtca acacttttaa gtgttattac ctcagctaag
    15601 cctaaaattg gtgcctacca ctttaccact attgtaccaa atttaggtat ggttcgcacc
    15661 caatcaggtg aatcctttgc agtagccgac ttgccaggtt tgattgaagg ggctagtcaa
    15721 ggtgttggtt tgggaactca gttcctccgt cacatcgagc gtacacgtgt tatccttcac
    15781 atcattgata tgtcagctag cgaaggccgt gatccatatg aggattacct agctatcaat
    15841 aaagagctgg agtcttacaa tcttcgcctc atggagcgtc cacagattat tgtagctaat
    15901 aagatggaca tgcctgagag tcaggaaaat cttgaagaat ttaagaaaaa attggctgaa
    15961 aattatgatg aatttgaaga gttaccagct atcttcccaa tttctggatt gaccaagcaa
    16021 ggtctggcaa cacttttaga tgctacagct gaattgttag acaagacacc agaatttttg
    16081 ctctacgacg agtccgatat ggaagaagaa gcttactatg gatttgacga agaagaaaaa
    16141 gcctttgaaa ttagtcgtga tgacgatgcg acatgggtac tttctggtga aaaactcatg
    16201 aaactcttta atatgaccaa ctttgatcgt gatgaatctg tcatgaaatt tgcccgtcag
    16261 cttcgtggta tgggggttga tgaagccctt cgtgcgcgtg gagctaaaga tggggatttg
    16321 gtccgcattg gtaaatttga gtttgaattt gtagactagg agactggtat gggagataaa
    16381 ccgatatctt tccgagatgc ggatggtaat tttgtttccg ccgcagacgt ttggaatgaa
    16441 aagaaattgg aagaactatt taatcggctc aatccaaatc gtgccttgag attggcacga
    16501 actaaaaagg aaaatccatc tcagtaaaga agctaaaaaa tccggctctt tgtcaactgt
    16561 agtaggttga agaaaagcta agcttgagaa aggacaaatt tcgtcctttc ttttttgatg
    16621 ttcagagcga taaaaatccg ttttttgaag ttttcaaagt ttcgaaa
//
LOCUS       DAVKXA010000047        16415 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKXA010000047 DAVKXA010000000
VERSION     DAVKXA010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.047"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(288..1850)
                     /gene="guaA"
                     /locus_tag="VW883_001662"
     CDS             complement(288..1850)
                     /gene="guaA"
                     /locus_tag="VW883_001662"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0274767.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLIHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1992..2690
                     /locus_tag="VW883_001663"
     CDS             1992..2690
                     /locus_tag="VW883_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0274768.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2733..3629)
                     /locus_tag="VW883_001664"
     CDS             complement(2733..3629)
                     /locus_tag="VW883_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0274769.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3638..4573)
                     /locus_tag="VW883_001665"
     CDS             complement(3638..4573)
                     /locus_tag="VW883_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0274770.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4570..5295)
                     /locus_tag="VW883_001666"
     CDS             complement(4570..5295)
                     /locus_tag="VW883_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0274771.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5379..6014)
                     /locus_tag="VW883_001667"
     CDS             complement(5379..6014)
                     /locus_tag="VW883_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0274772.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVACDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6016..6843)
                     /locus_tag="VW883_001668"
     CDS             complement(6016..6843)
                     /locus_tag="VW883_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0274773.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6865..7200)
                     /locus_tag="VW883_001669"
     CDS             complement(6865..7200)
                     /locus_tag="VW883_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV0274774.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7201..7917)
                     /locus_tag="VW883_001670"
                     /pseudo
     CDS             complement(7201..7917)
                     /locus_tag="VW883_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8430..9041
                     /locus_tag="VW883_001671"
     CDS             8430..9041
                     /locus_tag="VW883_001671"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0274775.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9086..9814
                     /gene="rlmB"
                     /locus_tag="VW883_001672"
     CDS             9086..9814
                     /gene="rlmB"
                     /locus_tag="VW883_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0274776.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9853..10764)
                     /gene="trxB"
                     /locus_tag="VW883_001673"
     CDS             complement(9853..10764)
                     /gene="trxB"
                     /locus_tag="VW883_001673"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0274777.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10830..11054)
                     /locus_tag="VW883_001674"
     CDS             complement(10830..11054)
                     /locus_tag="VW883_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0274778.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKVRQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11132..11875)
                     /locus_tag="VW883_001675"
     CDS             complement(11132..11875)
                     /locus_tag="VW883_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0274779.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11875..12675)
                     /locus_tag="VW883_001676"
     CDS             complement(11875..12675)
                     /locus_tag="VW883_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0274780.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12833..13189)
                     /locus_tag="VW883_001677"
     CDS             complement(12833..13189)
                     /locus_tag="VW883_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0274781.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNREAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13183..13713)
                     /locus_tag="VW883_001678"
     CDS             complement(13183..13713)
                     /locus_tag="VW883_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0274782.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13713..14207)
                     /locus_tag="VW883_001679"
     CDS             complement(13713..14207)
                     /locus_tag="VW883_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274783.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14342..14788
                     /locus_tag="VW883_001680"
     CDS             14342..14788
                     /locus_tag="VW883_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0274784.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14785..15432
                     /locus_tag="VW883_001681"
     CDS             14785..15432
                     /locus_tag="VW883_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0274785.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIIYYM"
     gene            complement(15784..16356)
                     /locus_tag="VW883_001682"
     CDS             complement(15784..16356)
                     /locus_tag="VW883_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274786.1"
                     /translation="MFLIKFLMRIFPTENYVINTGFWNLLSNPSYLKSIQTSMSMGVT
                     LISGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIITSSISLTILSSNKDIED
                     IKQLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILILVSIIGQFLGRSLVDI
                     SGFWQPSLIVISLLVIFYSITKGFYLFQDR"
BASE COUNT         5007 a         3661 c         2880 g         4867 t
ORIGIN      
        1 aaacttatca agcgcaatgc ctttggtttt cgaaactttg aaaacttcaa aaaacggatt
       61 ttcatcgctc tgaatatcaa aaaagaaagg acaaaatttg tcctttctcg agcttagctg
      121 acttcaaccc actacagttg acaaagagcc attttttgtc caaatgtaaa tcacttggaa
      181 ctattattca atttattctt tttagtaaat gttcccgttt taatcccagt tacagttttt
      241 aatcctctgt aaccgttgat tttacaaagc ttttaatttt tttgcgatta ctcccactca
      301 actgttgcag gtggtttact tgtaatatcg tagacgatac ggttaacatg atccacttca
      361 tttacgatac gtactgagat tttttgaagt acttcccatg gaattttggc aaaatcagca
      421 gtcataccat cgatagaagt gatagcacgg attgcaatcg tgtagtcata cgtacgaccg
      481 tcacccataa caccgactga acgaacgcct gtgttaacag tgaagtattg ccaaatatcg
      541 cggtcaagtc cagctttagc gatttcttca cgaagaatag cgtctgattc acgaacggtt
      601 tcaagtttct cttcagtgat ttcacccatg acacggatag caagtcctgg tcctgggaat
      661 ggttggcgcc atacgatatg gtctggcata ccaagctctg taccaagagc acgaacttca
      721 tccttgtaaa gagtattgag tggttcaatc aattcaaact gcatatcttc tggaagacca
      781 cccacgttgt ggtgtgactt gatagtttga gctgtatccg taccagactc gataacatct
      841 gtatataaag taccttgagc aaggaatttc acatctttga gcttgcttgc ttcgtcatcg
      901 aatacataga caaactcgtt accgatgatt ttacgttttt gttcaggatc agaaacgcca
      961 gcaagtttgt caaggaaacg tttagcagcg tctgctttga cgatattcaa accaaactta
     1021 ccaccgagca tgtccataac ttgatcagct tcgcctttac gaagaagacc gtggtctacg
     1081 aagatacaga tcaattgatc gccaatcgct ttttggagaa gaaccccaac gacagatgag
     1141 tcaacaccac ctgatagacc aagaaggaca cgtttatcac cgacggtttc acgaattttt
     1201 ttgatctgca tgtcaatgaa attatccatt gaccagtcac ctttagcctt acaaatgtta
     1261 agggcaaagt tacgaaggat atcatttccg tatacagaat gacgaacttc tgggtggaat
     1321 tggataccgt aaatgtgttt atctgggttt tcgatggctg cgtatgggca gtcagctgat
     1381 gtacctgtac gaacaaagtc agcaggaatc tcagtaaccg catcaccatg gctcatcaaa
     1441 acagtctgtt catcaggtgt tgattcaaaa agcgctgatg gtgtgtgagt tagggttgat
     1501 tgaccgtatt cacgatttcc agcatcacct gcaggaacaa cttttcctcc aagtttatgg
     1561 atcaataact gcataccata acagattccc aaaattggaa ttccgagttc gaagatttct
     1621 gggtcaatat caaatgaacc atcttcatat acagaatttg gaccacctga tagaataatt
     1681 cctacaggat tgacttcacg aacttcagca gctgaaattt tatggctttt tagttctgaa
     1741 aaaacaccaa tctcacggat acggcgtgaa atcagctggt tgtactggct accatagtcc
     1801 aatacgatga ttttttctac atcttgcaaa tcagttgaaa tgttgctcat ctttttcctt
     1861 tctcaaaaga aatatctttt cccaatattc tatcacaaat aagggcgaat taccaactaa
     1921 acaaggcgaa gtttgacttt ttctagttta ttggggtaca atagagaaaa gatagaaatg
     1981 aagtgaaaaa tatgctacct gcttatatga aaatccatga tcagataaaa aaggatattg
     2041 acgagcaccg ttgggctatt ggtgagaggc ttcccagtga aagagattta gctgagcagt
     2101 ttgcggtcag tcgcatgacc ctccgccaag ccgtatctct attagtcgaa gaaggcgtct
     2161 tagagcgccg tgtaggaagc ggcacctttg tttccagtac tcgagtacaa gaaaagatgc
     2221 gagggacaac cagttttact gaaattgtca aatcccaagg taaagttccc tctagccagc
     2281 tcatttccta caaaaaaacc attcccaatg agcaagaagt tgccaagcta ggaatttttc
     2341 caacggacaa tattatccga atggagcggg tccgctatgc cgaccaagtt cccctagttt
     2401 atgaagttgc ttctattcct gaaaaattca ttaaggactt taaaaaagaa gaaatcacca
     2461 gtcatttctt ccaaaccttg caaaaatatg gctatcgtat cggcaaatct caacagacca
     2521 tctatgctcg ccttgctaaa gaaaagattg cccactattt ggaagttgaa aaaggacatg
     2581 ctattcttgg attgacccag gtttcctacc tagaagatgg tactgctttt gaatacgtaa
     2641 aaagtcaata tgtaggcgaa cgctttgaat tttatcttga aaataattag attaccacgc
     2701 aaaaactctc tgtcacggac aaagagtctt ttttattttt ctaagaataa atctttcaaa
     2761 gaaatcaaag ttacagcaaa caatatcatt gccataccaa gaaaatcaat gggataaaat
     2821 tgttcattca ttattaagaa ggcaaagaaa atcgccgata ttggctcaat tgaagccaac
     2881 aagcttgact tgaccggtcc tatcagactg gctcctttaa ggaaagctgt ataggcaaag
     2941 acagtcccga taaggataat gcctgcaaac gcaaggagaa aatcaagact agtcgggata
     3001 tcggcctgta gaacccctgt aaaaggaagg gcgaccaaac ctgctatgac cattcccaca
     3061 ccaatgacca agctgctccc ccacttttta atcaaggcta tgggtaaaat gatatacaga
     3121 gcataagtca aggcagaaaa gagaccccag aacagaccag caggtgtcat ggataactgg
     3181 tccaactgcc catgtgttgc gatcaggaag gttcctccga tggcgaatat gatggaaact
     3241 atctctccca gtgtcggtgc caccctatcc ttgatacagc tataaattaa aattccgaca
     3301 ggacaaacat actgaagcac cgtcgctgtt cccgcattgg tctcctgaat agcagacaga
     3361 taggcgaatt ggttgagaaa aagaccaatc agagcaaaaa taagaagaga cagcaaactc
     3421 tttctatcct ttaaaaagac cagtatttta tcctttgcag tagcataagc caagagcatg
     3481 agaattccac cagcgattaa aagacgcaag ttggtcaaga ccagagccga aattccgtgt
     3541 gccattaggt attggccact cgttcctgac aacccccaag caataccagc cacaactgtt
     3601 agtaaagtcc cttttaaact atttgacatg tctctcctta ctcttctttg cgaatcaagt
     3661 tcatcacttg attgcggtct aatatccatt gagctctctc gtccttttca taggtacgat
     3721 tcgataggaa aatagtggct tcttgcttct gacgattcca catgataaag gtacctgtat
     3781 agcccgtatg gtctagccaa tctccttcca aattccatgc taaagaacgt tccttgtcat
     3841 ccaaaggaga aaaattttga tttaagtctc ttgcaaaatc atctgctaaa tagtgttcta
     3901 aaaagatttg taaatccttt atagtcgaaa ataaaccagc actcccagca tgtctaccca
     3961 ggagacgagc cttgggatca tgcactatgc ctgcctctac acctctaact gttggaacag
     4021 caagctcaac tggcccaaac ttagtttccg tcattcccca aggtttccag acttgatcct
     4081 ttaaaatcac atccaaatct tgattaaaaa ttctttccaa aataaagccc aacagcaaaa
     4141 aatggacatc cgaataaaga aaggctggct gacttcgtct gttgagatga aacatcgctt
     4201 cctttaattc aggggctgtt aaaagatcac gattaggaat aaaaggatca aggtctgttg
     4261 catgagtcaa gagctggcga atagtgatgt ctggataatc actctcaggt aaaaaatcta
     4321 ttaccagtct atcaatatct aattgaccta tttcccacaa gaaggtacaa actgtgccaa
     4381 ccccaacaac cttactgaca ctagctaggt cataaactag tcctgcctca gtctgcaagc
     4441 catgctctgg gtcactctgg cctaaataga actctgtcca ttgattgtcc ttaaaatacg
     4501 caaaagaggc tccgggataa attcctgcct cgatttgttc ttctattttt ttaataatct
     4561 tggtccactt catacttctt caaaccacaa ttcaacatta tttctatctt taccaaggaa
     4621 gaatttttca gacttaggaa taaaatattc agtagactca aacttctggc gaagacttgc
     4681 tatgtctaat tcattgacca agaacttgag catagataag tcccaggtaa ccgtattgtc
     4741 cacagtcaaa tcctgcccct gagctggaat aaaatcaagg gatgccccaa tttcagatga
     4801 ttccaagaaa ctttcgatat cagttgggag atgtaattcc atagaaatct caaatttact
     4861 taaagaaatt gatgccaaat ctgtttgaaa ttcaggcttt tctcctactt ctactagact
     4921 tgctctgtca tcttccgcat gaatcaaaat caaatcatct tctggtgaga aaatttcaaa
     4981 agcgtagcca ttttgacctt tatataatcg atgaatcgaa tctgttttag ataagattcc
     5041 ttcaatttct aagggatttt ccaccttgac aatcaatcta gctagttttt ttcttccctc
     5101 taccttacga gtacgcatac tgggagcttc ttctaaaacc agcttttcaa gacccgtttg
     5161 gtcacctagt gacagaaagg ccgattcttc taacaaggcc ttcattccaa gggtttcaat
     5221 ataaaatgtt tcatttaatt ttctattatt agcttttaaa gtaggaataa tccgtacaat
     5281 ctgatttaca ttcataaatt cctccgtcac tttttatttt aaaggatttt agaatttttt
     5341 acaagatatt atgctcaaat ttaacattat ttagctattt agtaaagata gtctttcaag
     5401 gcttttgaca aagcctgata accagcaata ctgaggtgca gtccatcagt tgtatattct
     5461 tttttgagtt ggcctgcttg gtctgtcaaa caatcaaata ctggcacaaa ttccacctgc
     5521 atataggcag atgcaagctc ttgataggct tgattccagt tctgaatttt ttcattcgag
     5581 cggatataga ctgcctgctg gtactcctct ccctcattga caggcaaaat ggaaagcaat
     5641 ttaatctctg tcaatggata atcgcaagca acggattgaa tgatagcttc gagattattg
     5701 agagcctcat tcacaggaac atcctttccg atatcatttg tcccaatcag aagaaaaatt
     5761 ttatctactg ctccaccata tagatgagca tcaaggttct ctagtaacag tcctgtctga
     5821 tagccacgaa ttcctcgatt gacaatcgtc tttgaagtcc caaatagctc ctgtagagga
     5881 taatactcga caatggaatc cccaataaaa agaatgtttg gttctacaac agaaatgtga
     5941 tttaggtgac gatacttggt ttgaattttt tcttgttcct ttaggagcca attttctaat
     6001 aactgtactg ccacttcatt ctcctttttc taaccagttt tccaagactt gataaactcc
     6061 tccttggctg ttggctggtg ctagagcagt cgccacagct ttggctttct catcagcatt
     6121 ttccatcgca taggcaattc cagccatttc aagcatttca acatcatttt cactatcacc
     6181 aaaagccatg atttcttggg atttcaagtc ccagcgcttg agtaattcct ccaagcccca
     6241 tgctttatga atcccagctt ggaggatatc aatgcaacca tagccactgg atacagctcg
     6301 gacacggcca tcaaagagag cattgatttc ttccaaaacc gaactcaaac gttcctcacc
     6361 aacaaccatg ctcatcttga gcacaccacc aaagaggtca gatgttaatt catccacaaa
     6421 ttgcatccgt tggtagaatt tttcaatcat ttctggagtc ataaaacttt caagatctgt
     6481 aaaaatcgta ccttccttga caaaatcacc cttcatcccc gttacaacaa actggtcctg
     6541 acacgctcga cccttgaaat gagccaaagc cttgttgaca atggcgtcat cccatgtctg
     6601 agcctgaatc aattcattgt tttcaaaaat acgagcgcca ttagcaacaa ccagaaccac
     6661 tcgatccacc aagggactca gtagttgtct catgcggtga atttcattgc ccgtcgcaat
     6721 gacaaaacga atgccccttt gatccaactg atctaaaatc ttttccaatc gtgggagatc
     6781 aagctgacct ctagcatcca gcaaggtccc atccatatct gtcgcaatta ccttaatcat
     6841 catttacttt cctctggatt caagctaata ccacttcaat cccacatgtt cattcatttc
     6901 tttataggct gtatcaattc gttccttagt cgcttcatct aactggtcac gatgactgcc
     6961 accctctata aaatcttcca aaatataagt ttggtaatga tacaagggat atccttctgg
     7021 tgaaaaggtt ccctttggtg ttcgattgac ccaagtagga tgagctttag ctgttccgat
     7081 agttgttttt ccatccttct tcttgatggt gacatccatg agaacaccac gttcagtcca
     7141 cttagcattc tcttcatctc ccatagattc aatccgttga ttggaaatga agttccccat
     7201 ttaatagata atgagtttct tatctccatc tttttcaacc gtttcagatg gttcaacaac
     7261 gtgaggatgc cctccaaaga taatatccgc tccccaatcg atcatcttgt gataaagagc
     7321 tttttgttct tcagttggtt ccaatcgata ctcaacaccc atctgaagca tgataatggt
     7381 gatatctgct tccttctctg cccgttcaat ttcagccttc atcttatctt cgtttaaatc
     7441 tgaaagataa cgattatagt cttcctgaga aatatactgc tcaattccat tgaaaccata
     7501 ggaataggct aacaatgcaa ccttgatagc attcacttcc ttaatgacca gcggagcctg
     7561 aacacgtggt tcgtgcgtat aaactccgat tggagtgatt ccagctttct caataatatc
     7621 ggccgttgaa ataactccct caatttgcga atccaaaata tgattatgag ctaaatccag
     7681 cacatgataa cctgcctcct taatagcatc cataacttca gcaggagcat taaagagaag
     7741 ataacccgct aaataatgat ccttattaat ggttccttca aaatcaccaa tagctaaatc
     7801 tgcttgcttg agccaaggag tcacatacta aaaattttca tgaaagtcat aggtaccgtc
     7861 ttctttttta gctgaaaaga aaagtccatc gtggtagagc aaatccccgt gggccataat
     7921 tctggcagtt ttttcctctt cctactcctg agacctttgc ttagtcccct cttgagaaat
     7981 agtatctcgt ttttgactag tcaagggatt ccttggaagc tttcaaacaa caagaccaag
     8041 cccattgata aaccaactgc tagcaagagt atcgccacaa atcccttatt gctccacttg
     8101 cgataactcc taaaaagttt accaagccct tcataaaacg aaaagctaaa ccaccctgat
     8161 ttcgattttg tcttctttgt atcttcattc tccctacttt cttatgcaag ccttttcttt
     8221 ttattatatc acagataagt atttctttca caattgaatt gaacttccca tctattttct
     8281 ataaatccta aatgccataa tgctttcaat tcttgtcatt ttgtgatatc atgtagagga
     8341 aatgaactaa tccacagtgg cttattccaa gtataccact tgggctttgg cagtagctaa
     8401 ctgcactaaa cataatataa ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg
     8461 ctcacttaat tgatatgaac gatattatcc gtgaagggaa tcctactcta cgcgcgattg
     8521 ctgaggaagt cactttcccc ctatctgacc aggaaatcat cctaggcgaa aagatgatgc
     8581 aattccttaa acattcccaa gatcctgtca tggctgaaaa aatgggactc cgcggtggtg
     8641 ttggactggc tgctccccag ttagatatct caaaacgcat tatcgctgtt ttggtaccta
     8701 atattgttga agaaggcgaa actccacagg aagcctacga tttggaagcc attatgtaca
     8761 atccaaaaat cgtctctcac tctgttcaag atgctgctct tggcgaagga gaaggttgcc
     8821 tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca tgcccgcgtt actgttgact
     8881 actttgacaa agatggagaa aaacaccgta tcaaactcaa aggctacaac tccattgttg
     8941 ttcagcatga aattgaccac attaacggta tcatgtttta cgatcgcatc aatgaaaaag
     9001 acccatttgc agttaaagat ggtttactga ttcttgaata aagaaaatcc cgttgcaaga
     9061 cggggttttg tgttataata gaggcatgaa aacaaatgat attgtctatg gtgtccacgc
     9121 cgttaccgaa gccctccttg caaatacagg aaacaaactc tacctccaag aagatctccg
     9181 aggtaagaat gttgagaaag tcaaggaact agctacagaa aagaaggtgt ccatttcttg
     9241 gacatcaaaa aaaaatctct ctgagatgac tgaaggtgct gttcatcaag gttttgttct
     9301 acgagtgtct gaatttgcct atagcgagct agattacatc cttgcaaaaa cacgccaaga
     9361 agaaaattca cttctattga ttctagatgg tctaaccgat ccccataatc tgggttctat
     9421 cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc attcccaagc accgtgctgt
     9481 cggagtaact cctgtcgttg ccaaaacagc cacaggtgct attgaacacg ttccaattgc
     9541 ccgagtaacc aacctcagtc aaaccttaga taaactcaag gatgaaggtt tctggacctt
     9601 tggaacggat atgaacggta ctccttgcca caagtggaat acaaaaggga aaatcgccct
     9661 catcattgga aatgaaggaa aaggtatctc tagcaacata aaaaaacagg tcgatgaaat
     9721 gattaccatt ccgatgaatg gacatgttca aagccttaat gccagtgttg ctgcggccat
     9781 tctcatgtac gaagttttcc gaaatagact ataaaaaagt ttccagtcat ctgattggaa
     9841 acttttttat gattaactat gttctgtaat gaatttatag gcttcttgac cagcgatagc
     9901 tccatctcca actgctgttg ttacttggcg aaggtctttc aagcgaacat ctccaactgc
     9961 aaagataccg tcgactgcag tcttcatgtg gctatctgtc acaatccagc ctgcctgatc
    10021 ttggatattc aattctttaa caaaatcgct aagagggtcc aaaccaacat agataaagac
    10081 accaccgaag gcttgctctg tcacttgacc tgttttcaca ttttcaaaaa cgacagattc
    10141 tactctgttt tcacccttga ttttccttac tacagaatcc catataaagc tgattttctc
    10201 attggcaaag gcgcgatctt gtaaaacctt ttgggcacga agttggtcac gacggtgaac
    10261 aatggtaaca gtcttagcaa aacgagtcaa gaagagggct tcttcaacag ctgaatctcc
    10321 accaccaact accaataaat cttggtcacg gaagaaagca ccatcacaca cagcacagta
    10381 agaaacacca cgactgttca gttcttcttc tccaggcact cccaaaggac ggtgtttaga
    10441 accagttgct acgataactg tacgtgtttc atatgtttgg tcatcagtca tcactttctt
    10501 aaaatcacca tggtcttcga cattttcaac ataaccataa atgtgctcaa caccaagatt
    10561 ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca ctaatattag cgtatcctgg
    10621 gtaattttcg atatcagatg tattattcat ctgaccacct ggcagaccac cttcaatcaa
    10681 agctactttt agattgcttc gagcagcata caaggccgca gtcatccctg caggtccagc
    10741 accgataata atagtatcgt acatatagat tccttctttc ttgttgtaac tatctttatt
    10801 ctaactcttt cttgtcaatc acgcaaggat tatgccttga aaacaagaat taaactcata
    10861 accgcaaagg ataatactgg gacaaccaag actccaatca taatcatatc atagagatgg
    10921 gcttggcgaa ccttggctgt cttatcaact cccgacatgg ctctcagacc aatccaaatc
    10981 cctaaaaaaa tcagaacaag gatggtggtc aatatcaaac tctcgaaata taaagaaaat
    11041 agttgcagta gcatgatttc tctcatttct atctttttta aagagtaaac tcagctagtc
    11101 caactaactg agttttcctt tatctattat atcaaatata agtccgtttg taactagcga
    11161 agaattcttt tgtccgctct tctttagggg tgtggataat ctcatccggt gttccagact
    11221 cgatgatttt ccccttatct aagaagagaa tcttatcagc cacttgggct acaaaggaca
    11281 tgtcatgact aaccaaaatc atggtttgac ctgacttagc agcatctgca atagactttt
    11341 ctacttcacc aaccaattct gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat
    11401 ctggtttcat agcaagcgca cgcgctaggg caacccgttg cttctgtcca cctgataaat
    11461 ggcgaggata atggttttca cggtccgaaa gcccaacctt agccaactct tccttggcaa
    11521 tcttagtcgc ttcttggtca gataatttct tgacaacaac caagccttct ttcacattat
    11581 caagtgctgt tcggcgttca aacaaattaa actgttggaa aaccatagac aacttacgac
    11641 gtagggcaag gatttcttct tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct
    11701 gaatagagcc actgtcaggt gtttcaagat aattgagact gcgaagaaag gttgattttc
    11761 cagctcctga agaaccaatc aaggctacaa cttccccttt ttgaatatcc aagtccagat
    11821 gatccaagac agtctgtcct gaaaaggatt tgcttaaatt tgaaatctta atcattaacg
    11881 aaggtctcct ttcacatctg tttgcactgt atcaggtgca gaaatagcca tttttctctc
    11941 gatgaaacga ccgaggcttt caattccgat attgaccacc caataaacaa gggcaacgga
    12001 gatgaagcgt tcaaaatagc gataatcagc tccacctaga atctgagctt gggcaaagac
    12061 ttccacaaca cccgcactaa aagctagaga tgttcccttg gtcaaaccga tgagggaatt
    12121 aatcaaggtt ggagtagcta ccaccgctgc attaggaata atcactcgtc gataaacttg
    12181 cgctcgggtc atacccagac tgcgtgccgc ctcaatctca ccaggattaa ctgagagaat
    12241 ggctgcacga atggtttcac tagcataagc tgcctcatta aaggcaaagg cgacaatcgc
    12301 aaaagctgca gctggaatcg cattgatatt gagaccagtt ccccattgct gattgagggc
    12361 tttcaaagcc aaagggattc cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc
    12421 ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa atcttgacac gattgatctt
    12481 cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat
    12541 aattgttgtt ggaagttgtt ggacaattct agggattcca tcaaagaccg aacgtaggct
    12601 aaacagcttg ccatccggaa tcaattgcat caagttttgg taccaatctg atgctaaaat
    12661 cgttgtaaca ttcataaaaa catcctcttc tgataatgat tcattctacc atgcttctgc
    12721 cgtcaatgaa attatttgct acggtcagat acagactttg tctacctact agtttatcat
    12781 actttgaaac agggaagtta tatattttat ctatcaaaga gatagataaa aactatttca
    12841 gtcccagttc ttcataagat tttcgataac cgatttgctt aacagttcca ttttctacta
    12901 aaatgggccg ttttaacaac ataccgtcac ttgctagcaa ctcagccgct tctcggtttg
    12961 acaaacttcc taccttatct tttagcccta attcacggta tttgatccca ctggtgttga
    13021 aaaattgctt caattcaaat cctgaggttt ctagccaatt caaaatgact tcttggctag
    13081 gtgtttcttc cacgatatgg acggctttat agtccacacc taattgattt aattcttgtt
    13141 ttgctttttt acaagttgaa catttggggt attcgataaa ttctaacatg tgcttctcct
    13201 tctattgttt ctatctttaa aatctactcc ttcatgctcc aagagccaag ctttcttttc
    13261 cactcctgca gcatagcctg tcagacgctt gcctgctccc aacacacgat gacaaggtac
    13321 taggatagac caaggattgc gtcccactgc tccaccaatt gcttgagcag aagccacttg
    13381 caggtcttga gcaatttgtc cataggtcac tgtctgacca taaggaattc cctgtaaata
    13441 ggaccaaact ctcttttcaa aattcgttcc aattggcgcc aagagcaagt tggataaatc
    13501 ctgaggctcg cctttaaagt aatcatctaa gcaagcaata actggatcta aaataggatg
    13561 actaacaact tcttctatcg tttcatctcc tagtcccctc tcaaaatgct tctgctcctg
    13621 aacccaaatt ccatacaaat aatggtcatc agctacaagt gatagaatac caattggtga
    13681 ggagtagagt atttttacat acttcttttg cattatttct ttaatttttg ataggccaag
    13741 cgttcgccat ctactggcac cttaccaact tgtttaaaac caagtttttc aaaaatatgt
    13801 tgcataacct tgttttcagc atgcgtatct gagcgaaaat caagataatc aaaaccttca
    13861 atcaagccct ctaagaaggt ttgagcaact ccttttccct gcacatctgc tgccacagca
    13921 atacggtgaa agactagata ctctgactct ccagcttgcc agtttccctc ataaatagct
    13981 tcataggcct cctctggact cttggtcaca gcagcatagg ctagcagttc tccctcttcc
    14041 aaggctacgt aggcttgccc tgagataata tcatcgataa taacatctgc atttggatag
    14101 ccattttgcc actggtcact accagcatct gctaaacatt ttttggcatc ctccatcacc
    14161 tgcatgatgg catctacttc atttggaaaa gctaaacgaa tttccatctt ttttcctcat
    14221 ttctgactag tttctcccat catagcataa tttaagtatt tctacaagca gttaaaactt
    14281 gactttgtgt ttttgttatt ttataatcta gttatcaaaa ctatataaaa aggagttgaa
    14341 aatgaaaact accttttcct acccaaaatg ggcagaaatt ccaaacattg acctctatct
    14401 ggaccaggtt ttgctctatg tcaatcaggt ctgcgcccct atctctccta ataaagacaa
    14461 gggcctaaca gcatctatgg tcaacaatta tgtgaaaaat ggttacctga caaagcctga
    14521 caaaaaaaaa taccaacgcc aacagattgc ccgtttgatt gctatcacaa ccctcaagtc
    14581 tgtattttct attcaagaaa tagcccagac acttaatact ctacaaactc aagcaagttc
    14641 agaccaactc tacgatgctt ttgtggacta catgaaccaa ggaattgacc cagctaaccc
    14701 tattatccaa accagctgcc aaaccgttaa actctatcat caaactctag acttaatcga
    14761 tcatactcaa gaggaggtaa tccaatgaac actagtctta aactcagcaa acaactcagt
    14821 tttggagagg agattgctaa tagcgtgacc catgctgtgg gtgcagtcat catgcttatc
    14881 ttgctgccta tttcatccat ctatagttat gaagcacacg gatttttatc ctctatcggc
    14941 gtttccattt tcgtcatcag tctctttctc atgttcctat catccaccat ttatcactct
    15001 atggcctatg gttcgaccca caaatatgtt ttgcgaatca ttgaccattc tatgatttac
    15061 gttgccattg ccggctcata cacgcccgtt gtcttgacct tgatgaataa ctggtttggc
    15121 tatctgatta ttgtcatcca atggggaacg accatctttg gtattctcta taaaatcttt
    15181 gctaaaaagg tcaatgagaa atttagcctt gctctttacc tgattatggg ctggttggtt
    15241 ctggctatca ttcctgccat tatcaatcaa acgacacccg ttttctggag tctcatggta
    15301 actggcggac tctgttatac agttggagct ggattttatg ccaagaaaaa accttatttc
    15361 cacatgattt ggcatctctt tatcctagct gcgtccgtac tccaatatat tgctattatt
    15421 tattacatgt aaaactctca gtaggcagag cctgcttaga gttttacaaa cgaatttccc
    15481 aaagaggaag caatatgaaa gcagtcattg cttgtgttca taaaattctc agaatcattt
    15541 acaaactact ctccaccaag tagacttatc aaaaagaaaa ggcgctagga ctgaagaaac
    15601 agttctaacg cccaaattaa aaaaatttca actacagtat agcacaggaa atgatttttt
    15661 gcgctttttt actgtttttt caaataaaaa aagacaaagt tttatccttg tcttttagtt
    15721 ttagtattgc tttggtttca atgtcaataa gtgtgttctt tttggttcag taactattcc
    15781 aatttatcta tcttgaaata aataaaatcc ctttgtaata ctataaaaaa taactaacaa
    15841 agaaataact ataagactcg gttgccagaa acctgatata tctactaaac tacgacctaa
    15901 aaattggcca ataatgctaa ctaaaattaa aataattaaa ttgaaaatta ctgacactaa
    15961 taaaattaac accgaatgta ttattgcctc gcctatacgt attttaaaaa gttgtaatct
    16021 tgacactccc agtgtcttta actgtttaat gtcctcaata tctttattag aagataaaat
    16081 tgtaagagaa atagaactag taataatcag aataattggt gcagacatat aagcaataaa
    16141 ggaagctctt gcttcgttta ctccgtttgc tgtattcatg aatgaataca tattttgggt
    16201 gtaaagaata aacccagaaa tgagagttac tcccatgctc attgaagttt gtatactttt
    16261 caaatagcta ggattggata gtagattcca aaagcctgta ttaattacat aattttcagt
    16321 tggaaatatc ctcattaaaa attttattag aaacatttga attgatggag atagtgattg
    16381 aataataagg atgtgaataa ttaataaaaa taata
//
LOCUS       DAVKXA010000048        15243 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKXA010000048 DAVKXA010000000
VERSION     DAVKXA010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.048"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            67..627
                     /locus_tag="VW883_001683"
     CDS             67..627
                     /locus_tag="VW883_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0274787.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     VFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            628..2013
                     /locus_tag="VW883_001684"
     CDS             628..2013
                     /locus_tag="VW883_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274788.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHVQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQRCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVMLLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDSLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            2015..2665
                     /locus_tag="VW883_001685"
     CDS             2015..2665
                     /locus_tag="VW883_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0274789.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLTQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            2676..3368
                     /gene="tenA"
                     /locus_tag="VW883_001686"
     CDS             2676..3368
                     /gene="tenA"
                     /locus_tag="VW883_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0274790.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            3373..3897
                     /gene="thiW"
                     /locus_tag="VW883_001687"
     CDS             3373..3897
                     /gene="thiW"
                     /locus_tag="VW883_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0274791.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            3897..4700
                     /locus_tag="VW883_001688"
     CDS             3897..4700
                     /locus_tag="VW883_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0274792.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGITTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            4693..5325
                     /locus_tag="VW883_001689"
     CDS             4693..5325
                     /locus_tag="VW883_001689"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0274793.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVRLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLIGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(5534..6325)
                     /gene="thiD"
                     /locus_tag="VW883_001690"
     CDS             complement(5534..6325)
                     /gene="thiD"
                     /locus_tag="VW883_001690"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0274794.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVYKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(6409..6507)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6691..7086
                     /locus_tag="VW883_001691"
     CDS             6691..7086
                     /locus_tag="VW883_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0274795.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            7097..7468
                     /locus_tag="VW883_001692"
     CDS             7097..7468
                     /locus_tag="VW883_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0274796.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            7478..9721
                     /locus_tag="VW883_001693"
     CDS             7478..9721
                     /locus_tag="VW883_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0274797.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            9928..11703
                     /gene="spxB"
                     /locus_tag="VW883_001694"
     CDS             9928..11703
                     /gene="spxB"
                     /locus_tag="VW883_001694"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0274798.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            11814..12161
                     /locus_tag="VW883_001695"
     CDS             11814..12161
                     /locus_tag="VW883_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0274799.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(12278..12519)
                     /locus_tag="VW883_001696"
                     /pseudo
     CDS             complement(12278..12519)
                     /locus_tag="VW883_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12690..12971
                     /locus_tag="VW883_001697"
     CDS             12690..12971
                     /locus_tag="VW883_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0274800.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            13103..14047
                     /gene="manA"
                     /locus_tag="VW883_001698"
     CDS             13103..14047
                     /gene="manA"
                     /locus_tag="VW883_001698"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0274801.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDTLLTKVPVKAG
                     DFFYVPSGTMHAIGTGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLFSILAGQGQL
                     TVDGKNYPIQKGSHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(14087..15004)
                     /locus_tag="VW883_001699"
                     /pseudo
     CDS             complement(14087..15004)
                     /locus_tag="VW883_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            15043..15243
                     /locus_tag="VW883_001700"
                     /pseudo
     CDS             15043..15243
                     /locus_tag="VW883_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         4424 a         2895 c         3417 g         4507 t
ORIGIN      
        1 gctatacaaa gtatttaggt cggtcttctt gagtgcccca cttttcttta aaaaaaggag
       61 ttttttatgt tgaaaaaatg gcagttaaaa gatgttatct tgcttgcttt cttgtctatc
      121 ttttttggtg gggttttcgt tggttcagga tatgtgtata atattctcag tctactctta
      181 acacctcttg gtttgcaggt ctttgccaat gaaatcctct tcggtctctg gtgtatggct
      241 gcgcccattg ctgccatctt tgttccgaga gtcggaagtg caacgattgg agaagtgcta
      301 gctgcgcttg ctgaagtcct ttatggtagc caatttggtc taggagctct tttgtctggc
      361 ttggttcaag gtttgggaag tgaatttggt tttatcgtaa ctaagaatcg ctatgaaagt
      421 tggctctctc taactgctaa tagtattggg attacgcttg ttagctttgt ctatgaatac
      481 attaagttag gttactacgc cttttccctt ccgtttgtcc tttccttact tgtggtacgt
      541 tttatttctg tttatttctt ctgtaccatc ttggttcgtg ccattgtcaa actctatcat
      601 cagtttgcaa ctggaggaaa agcatagatg ggtctggaac tacgagcgat tcagtcccca
      661 atcttctctg agccgtttga ttttactttt catgtgcaag cctttacctt gttagttggg
      721 agtagtgggt ctggaaaatc gagcctcttt caaatgattg cccaagttag ttctcttccc
      781 tatagcggtc aagtcctgat agatgggagt gaggtcagtc agctttctat cgtcgaacgt
      841 gtccagaagg ttggcattct ctttcaaaat cccaatcatc aatttaccat ggagaacttg
      901 tttgaggagc tgattttcac cttggagaat atcggctatc accttcagga aattgattct
      961 aaaatagcag aggttgtcca gcgatgtcgt tgcgaggcaa tcttacaccg tcccattcat
     1021 cacctatcag gtggggaaaa gcaaaaagca gcgctggctg tcctctttgc catgaatcct
     1081 agggtatatc tcttggatga gcccttcgct tccattgacc gcaagagcag aatcgagata
     1141 ttggagattc taaaagagtt ggctcttgat gggaagacag ttattttgtg cgaccatgat
     1201 ttatctgact ataaagccta tatcgaccat atggttgagc taagagacgg aaaactaagg
     1261 gaagtgtttc aaatcccttc ctatgagatg acacaggttg cttcaaagga agttgcttct
     1321 agcccggaac tattccatat gaaccgtgtg actggtgagc ttggtaatcg ccccctcttt
     1381 tcaattgctg atttcacatt ctatcaaggg atttcctgta tcctgggtga caatggtgtc
     1441 gggaaatcaa ccctctttcg gtctattctt caatttcaaa agtataaggg gagcattact
     1501 tggaagggtt cggtcctgaa aaagaaaaag agtttgtatc gtgatctgac tggtgttgtt
     1561 caggaagctg agaagcagtt tatccgagtc agtctgcgag aggagcttca attagatgga
     1621 cctgattctg aaagaaatca gcggattttt caagctttac gatattttga tttggagcag
     1681 gcagtcgata agagtcccta tcaattaagt ggtggtcagc aaaaaattct tcagctcttg
     1741 accatcttga ccagtaaggc ttccgtgatg ttgctagatg aaccttttgc aggtttggat
     1801 gatagagcct gccattattt ttgcaagtgg attgtggagg agaggaatca aggaagaagt
     1861 tttctgctca ttagtcatcg tttagactct ttgatttctg tggttgatta ttggattgag
     1921 atgactagtc agggtcttcg gcatgtgaaa gaagtgacca ttaccaaacc acttacatct
     1981 cagagtagca atacccaagg ggaggtgaga tagtatggtc aaagtagcaa cccagacacc
     2041 gattatcagt ctcttcttgc tgattttatc cttggaaaca tctttcattc cttcgattgc
     2101 tctgaatctt tcggtagtcg cattttgtat tctctttatg ctctattacc gtcgatttaa
     2161 aatgttagct tggatgatca tacttgccat tttaccatct tttgccaact actgggcagt
     2221 tcagttacac ggagatgctt cacaggcagt catgcttgga acgagggcct ttgtgacagt
     2281 ttgtatcggc cttgtctttg tttcctctat ttcactaaaa gagcttctct tgtacttgac
     2341 tcaaaagggg ctatcacgct cttggtccta tgccttgatt gtggtattca attcctttcc
     2401 tctcattcag caagaaatca agtccctcaa agaagcttgc ctattacgtg gtcaagaact
     2461 gcatttttgg tcgcccttga tttacagtaa ggttctgatg acagtcttta ggtggcgcca
     2521 tctttacctg agagctctgt ctgctcatgg atatgacgaa catgcacagt tgaagaatag
     2581 ctatcggact ttttatattc ctaaaaaaac aaaattaatc tacctgcttt tctttttatt
     2641 gcttcaaacc agtctatttt tataaaggag ttattatgga atttacagat attgcgatgg
     2701 aattatccaa gaaagcttgg caggcttcct ttcatcatcc ctttatttta caattacaag
     2761 aggggaattt agaacctgcc attttccgct attacctgat tcaggatgcc tactatctga
     2821 aggccttctc agaaatctat catcttttgg ctgataagac ttcaaaccaa gagatgaaaa
     2881 gactcttgaa acaaaatgct cagggtttag tggagggtga gttatttatt cgccaacaat
     2941 ttttcaagga aatggaaatc agcgaccagg aaatggagca acatccaatt gctccaacct
     3001 gttatcatta catttctcat atttataggc aatttgcaga accgaactta gccatcgctt
     3061 ttgcaagctt gcttccttgt ccttggttat accatgatat aggcaaatca cttaatctta
     3121 aaccatcacc aaatcctctc tatcaacaat ggattgaaac ttatattacg gatgagttag
     3181 agcaacagat cagagaggag ggagcactgg tcaatcagct ctatcgagaa agtgatgaga
     3241 cagataagca aaaaatgcta gatgccttcc acatcagtgt tcatatggaa gccaagtttt
     3301 gggagatggc ttaccaacac cagacatgga agagcgattt acagtcttta gaaaaaggag
     3361 aagaatagaa acatgagaaa gcaccaacta caagttcaca aattgaccat tttatctatg
     3421 atgattgccc ttgatgtagt ccttacacct atctttcgga ttgagggaat ggcaccgatg
     3481 tccagtgtag tcaatattct agcgggaatc atgatgggac ctgtttatgc cttggctatg
     3541 gctacagtga cagcctttat ccgtatgacg actcaaggga ttccgccttt agctctcaca
     3601 ggagcgactt ttggagccct tctagcaggt ctcttttata agtacggtcg aaaattttac
     3661 ttttctgcct tgggagaaat tgtgggaaca ggtattattg gttctattgt ttcctatcct
     3721 gttatggtgc tctttacagg atcggctgct aagcttagtt ggtttatcta cacgcctcga
     3781 tttttcggag caaccttgat tggtacagcg atttccttta ttgcatttag atttttaatc
     3841 aagcaggaat tctttaaaaa agtgcaagga tatttctttg ctgaaaggat agaatgatgc
     3901 aggcattgac aaatcctttt cctataggct ctagttccct cattcactgt atgaccaatg
     3961 agatttcttg tgagatgctg gcaaatggga ttttggctct gggatgcaaa cctgtcatgg
     4021 cagatgatcc ccgtgaagtt cttgatttta ctaagcaaag ccaggctctc ttcatcaatt
     4081 tggggcattt gtcagctgag aaggaaaaag caatccgcat ggcagctttg tatgcaaacc
     4141 aatcttctct cccgatggta gtagatgcgg ttggcataac gacttcatcc attcgtaaga
     4201 gcttagttaa agacctttta gactatagac ctacggtcct taaaggaaac atgtcagaaa
     4261 ttcgaagtct tgttggatta aagcatcacg gcgttggggt cgatgcgagt gctaaagatc
     4321 aagaaacgga ggatttgctt caagtcttga aagactggtg tcagacctat cctggtatgt
     4381 cattcttagt cacaggtccc aaggacctta ttgtttcgga gaatcaagtt gctgtacttg
     4441 agaatggctg tactgaatta gactggataa cagggacagg agacttggtt ggagccttaa
     4501 cagctgtttt tctcagccaa ggaaagactg gttttgaagc ttcttgctta gcagtctctt
     4561 atctcaatat cgctgctgag aaaatagttg ttcaaggaat gggattggaa gaatttcgtt
     4621 accaagtact caatcagctt tcgctcctaa gaagagatga aaattggcta gataccatca
     4681 aaggagaggt ttatgaatag agaagcgctt agactatatc tggtaaccaa tcgctatcaa
     4741 gattccgtgg aaagctttct tgcaaaagtt gagacggcct gccgttcagg ggttaccata
     4801 gtccaattgc gagaaaaaaa tctcacaacc aatcaatatt atcaactggc aaaacaagtc
     4861 aaggaaataa cagatgccta tcaggtccgc ttgataatcg atgatcggtt ggatgtttgt
     4921 cttgcggttg atgctgctgg tctgcatatt ggagatgacg aactcccagt ttcggtagct
     4981 cgcaaagtct tgggtcctga aaaaatcctc ggtgtcaccg ctaaaacggt taaaagagct
     5041 ctggaagcgg agaaatcagg tgcagattac ttggggacag gagccatttt tccgacaacc
     5101 accaaggaaa atgcacccat caccctgatt tcaaccttga aaacaatttg tcaaacggtt
     5161 gccattccag tagttgctat tggcggcttg acatcagaga atattgacca acttatcggc
     5221 acgggtatag ctggtgtagc tgttgtacgt gatttgatgc aagcagaaga tattgaggca
     5281 aaaacgcaag cctttttaac aaagttgcat gacattcttt cctaattaat actcaatgaa
     5341 aatcaaagag taaactagaa agctagtcgc aggttgctca aagtactgcc ttgaggtttt
     5401 agataagact gacgaagtca gctcaaaaca gtgttttgag gttgcagatg gaagctgacg
     5461 tagtttgaag agattttcga agggtataaa aactctctaa ttcccttaaa gtgggaacta
     5521 gagagttttt ttcttaatct ttaaaagttg tatggttgac tggaccagaa ccatgaccga
     5581 gttgaggggc atcttgaata gcttttgtga taaaggcctt ggccttataa actgcctggt
     5641 aaagactctt gcccttggct aattcagcag taatcactgc agcaaaggta catccagtac
     5701 catgggtgtg acaggtttga attcgtgggc tttcccagac aaattgttca ttcttggtaa
     5761 agaggaaatc tttagcacca cctttgagat gtccgccttt gataaccaca gactgaggac
     5821 caaattcttt taaaatcagg cgaccagcac gctgcatgtc ttcggggtca tggattgaaa
     5881 aaccaacaat ctcttctgct tcaggaagat ttggcgtaat aatagttgct agaggtagta
     5941 agtttgtttt gagatagtct ctagcacttg agtcaatcaa ggcatctcca cttgtagcaa
     6001 ccataacagg atcaaggaca tagggacaat ccagtttttt aagatagggt tggatgattt
     6061 ccatgatttc agtagtagcc aacattccag tttttacagc ctgaggtgga atatcagaaa
     6121 agacactctc caattgggct ttcaacattt gaggagaaac gtgctcgatt agctgaacac
     6181 ctctggtatt ttgagcgaca agactggtta caacagccat tccatagaca tctctcgctt
     6241 ggaatgactt taaatctgcc ataatgccag caccaccact agggtcagtc cctgcaatgg
     6301 tcaaagcaac gggtaaataa gtcatctaaa acctcccaac caactgaagt ttgtattctt
     6361 aagaacaagc tagtctgttt tagaaaggca atagaagact gctagtcccc attatcattt
     6421 ccacttccat cagctagcat tatctagatt gagtcagagg gatctaacag tcgttaatct
     6481 cagctttacg cacccctagt ggttgttttc ttttttcttt agtatagcat atttttattg
     6541 tttatatagt aatatttgac tgcaaatcgt ttttcaaatg attaaaattc tatttttcga
     6601 agaaaatatt atttctataa ttgacaaatg tagattttaa gagtatactg atgagtgtaa
     6661 ttgacaaatg tagattttgg aggtatggta atgcagattt cagatgcaga atggcaggtc
     6721 atgaagatta tttggatgca gggggagcag accagtacag atttgattag ggttttggca
     6781 gagcggtttg actggtccaa gtccacggtt cagacacttt tggctcgtct ggttgagaaa
     6841 gagtgtttga ctcggaaaaa agaaggcaag tcctttgttt attcagccct tttaactcta
     6901 gaccaaagtc gggatttact tgtccaagat atcaaagaca aggtttgttc ccgtaggatt
     6961 aggaatttgt tggctgactt gattgtagaa tgtgaattta ctcagactga cttggaagac
     7021 ttggaagctg tgatttcaga gaagaaatca agtgctgtaa cagaagtaag atgtaattgt
     7081 atgtaaagga gacgtcatgt taaatagtat tgtaaccatt atttgtattg cccttatcgc
     7141 atttatcttg ttttggtttt tcaaaaagcc tgaaaaatct ggacaaaaag cccagcaaaa
     7201 aaacggatac caagagattc gagtggaagt catgggaggc tatactcctg agttgattgt
     7261 cctaaagaaa tcagtgccag cacgcattgt ctttgaccgc aaggatcctt caccatgtct
     7321 ggatcaaatt gtttttccag attttggtgt acatgcgaac ctgccaatgg gggaagagta
     7381 tgtagtggaa atcacgcctg aacaggctgg agagtttggc tttgcttgtg gtatgaacat
     7441 gatgcacggc aagatgattg tagagtaggt ggagactatg acagaaattg tgaaagcaag
     7501 cttagaaaat ggcattcaaa aaatccgtat ccgagctgaa aaaggctatc atccagccca
     7561 tatccagctt caaaagggaa ttccagctga gattaccttt catcgtgcta ctccttcaaa
     7621 ctgttataag gaaattctgt ttgaagaaga aggtatcttg gaaccaatcg gcgtagatga
     7681 ggagaaagtc attcgtttta cgcctcaaga attagggcga catgaatttt cttgtggcat
     7741 gaagatgcaa aagggaagct atacagtcgt tgagaagact cgaaaatctc tatctctcct
     7801 gcaacgtttt tggattacta gtatctttac tgtgcctctt gtgattctca tgattgggat
     7861 gttggcaggt agcattagtc atcaagtcat gcattgggga acctttttag caacaacgcc
     7921 tattatgtta gttgcaggta agccatatat ccagagtgct tgggccagtt ttaaaaagca
     7981 caatgccaac atggatacct tggttgcgct gggaactcta gtggcttatt tctatagcct
     8041 agttgctctc tttgctggtc tccctgttta cttcgaaagt gctggattta tcctcttttt
     8101 cgttcttttg ggagcagttt ttgaggaaaa aatgagaaaa aatacgtccc aagctgtgga
     8161 gaaattactg gacttgcaag ctaaaaccgc agaagtcttg agtgatgata gttatgtcca
     8221 agttcctttg gaacaagtca aggtaggcga cctgattcga gtgcgtcccg gtgaaaagat
     8281 tgctgttgat ggtgtcgtag tagaaggtgt ctctagtatt gacgaatcca tggtgacagg
     8341 tgagagtctg cctgtggaca agacagttgg agatactgtc attggctcaa ccatcaatca
     8401 tagtggaacg cttgtcttta gagcagaaaa agttggctca gagactgttt tggctcagat
     8461 tgtggatttt gtgaagaaag ctcagacaag tcgtgcgccg attcaggact tgacggataa
     8521 gatttcaggg atttttgtcc cagtagttgt cattttagga atcatgacct tttgggtttg
     8581 gttcgtcttg ctcagggata gtgtggtcgt gcttggagct agctttgtgt cctctcttct
     8641 ctacggagtg gcggttttga ttatcgcctg tccttgtgcc ttgggacttg caacaccgac
     8701 agcccttatg gtggggacag gacgtagtgc caagatgggg gttctcctca aaaatggaac
     8761 tgtcttacag gaaatccaga aagttcaaac tcttgtcttt gataagaccg ggactttgac
     8821 ggaagggaaa cctgtggtaa cagatatcat cggtgacgaa gtagaagtgt ttggattggc
     8881 agcctccttg gaagatgctt ctcaacaccc actggctgag gctatcgtta agcgagcgag
     8941 tgaagctgga cttgagtttc aaactgttga aaattttcag gccttgcacg ggaaaggtgt
     9001 ttcagggcga atcaatggaa aacaagtttt acttggaaat gctaaaatgc tggatggcat
     9061 ggatatttct aatacttatc aagataaact agaagaacta gaaaaagaag ctaagacagt
     9121 tgtgttttta gctgttgaca atgaaatcaa aggcttgctt gctttgcaag atattcctaa
     9181 ggaaaatgct aagctagcca tcagtcagct aaaaaaacgt ggtctccgaa cagtcatgct
     9241 gacaggagac aatgctggtg tggcgcgtgc tattgcagat caaatcggaa ttgaagaggt
     9301 cattgcaggc gtcttgccag aagaaaaagc ccatgaaatc cataaactgc aacagtcagg
     9361 gaaagtagcc tttgttgggg acggtatcaa tgacgctcct gcccttagtg tagcagatgt
     9421 ggggattgct atgggagctg gaacagatat cgccatcgag tcagcagatt tggtgttgac
     9481 aaccaataat cttttaggag tggttcgtgc ctttgatatg agtaagaaaa cctttcatcg
     9541 aattctactc aatcttttct gggcttttat ctacaatgtt gtcggaattc cgattgcagc
     9601 aggagtcttt tcaggtgttg gactggctct caacccagaa ttggcaggtc tagccatggc
     9661 ctttagttct gtatctgttc tgaccagttc ccttctgtta aattttagta aaatagacta
     9721 aaagtaatga ctagatttct ttgttataaa acagaaatga cagaacttta aaaactgtat
     9781 tagaatagag aatagagagt tttgagcaga tttttagaaa agtcagcata aatatgatac
     9841 agtggaatag taaaaatttg gagaacgttt ccaattctat gtaatcgtat tctccaaatc
     9901 taaaaaaatt gaaggagagt tatcattatg actcaaggga aaattactgc atctgcagca
     9961 atgcttaacg tattgaaaac atggggcgta gatacaatct acggtatccc atcaggaaca
    10021 ctcagctcat tgatggacgc tttggctgaa gacaaagata tccgcttctt acaagttcgc
    10081 cacgaagaga caggtgctct tgcagcggtt atgcaagcta aattcggcgg ctcaatcggg
    10141 gttgcagttg gttcaggtgg tccaggtgcg actcacttga ttaacggtgt ttacgatgca
    10201 gctatggata acactccatt cctagcgatc cttggatcac gtccagttaa cgaattgaac
    10261 atggatgctt tccaagagct taaccaaaac ccaatgtaca acggtatcgc tgtttacaac
    10321 aaacgtgtag cttacgctga gcaattgcca aaagtaattg acgaagcctg ccgtgctgca
    10381 atttctaaaa aaggtccagc tgttgttgaa attccagtaa acttcggttt ccaagaaatc
    10441 gacgaaaact catactacgg ttcaggttca tacgaacgct cattcatcgc tcctgctttg
    10501 aacgaagttg aaatcgacaa agctgttgaa atcttgaaca atgctgaacg cccagttatc
    10561 tatgctggat ttggtggtgt taaagctggt gaagtgatta ctgaattgtc acgtaaaatc
    10621 aaagcaccaa tcatcacaac tggtaaaaac tttgaagctt tcgaatggaa ctatgaaggt
    10681 ttgacaggtt ctgcttatcg tgttggttgg aaaccagcca acgaagtggt ctttgaagca
    10741 gacacagttc ttttccttgg ttcaaacttc ccatttgctg aagtttacga agcattcaag
    10801 aacactgaaa aattcatcca agttgatatc gacccttaca aacttggtaa acgtcatgcc
    10861 cttgacgctt caatccttgg tgatgctggt caagcagcta aagctatcct tgacaaagta
    10921 aacccagttg aatcaactcc atggtggcgt gcaaacgtta agaacaacca aaactggcgt
    10981 gattacatga acaaactcga aggtaaaact gagggtgaat tgcaattgta tcaagtttac
    11041 aatgcaatca acaaacatgc tgatcaagac gctatctact caatcgacgt aggtaacact
    11101 actcaaacat ctactcgtca ccttcacatg acacctaaga acatgtggcg tacatctcca
    11161 ctctttgcga caatgggtat tgcccttcct ggtggtatcg ctgctaagaa agacaatcca
    11221 gatcgccaag tatggaacat catgggtgac ggagcattca acatgtgcta cccagacgtt
    11281 atcacaaacg ttcaatacga ccttccagtt atcaaccttg tcttctcaaa tgctgagtac
    11341 ggcttcatca agaacaaata cgaagataca aacaaacact tgtttggtgt agacttcaca
    11401 aacgctgact acgctaaaat tgcggaagct caaggagctg ttggattcac agttgaccgt
    11461 atcgaagaca tcgatgcagt tgttgcagaa gctgttaaat tgaacaaaga aggtaaaact
    11521 gttgtcatcg atgctcgcat cactcaacac cgtccacttc cagtagaagt acttgaattg
    11581 gatccaaaac ttcactcaga agaagctatc aaagccttca aggaaaaata cgaagcagaa
    11641 gaactcgtac cattccgtct cttcttggaa gaagaaggat tgcaatcacg cgcaattaaa
    11701 taattcctct cgccgaaaat caaatatgaa acttgtagac tttattcttt gattttcata
    11761 gagcagaact ttaaaagatc ggagcaatcc ggtcttttta tggaggagag taaatgaatt
    11821 taaatcaatt agatattatc gtttcaaatg ttccccaagt ctgtgctgac ttggagcata
    11881 tcttggataa aaaggcagat tatgctgatg atggttttgc tcagtttacg attggtagtc
    11941 actgccttat gttgtcacaa aatcatttgg ttcctttgga aaactttcag tcaggaatca
    12001 ttattcatat cgaggttgag gatgtagacc agaactacaa acggttgaac gagcttggta
    12061 taaaggtttt acacggacca actgtaaccg attggggaac agagtcctta ttagttcaag
    12121 gacctgctgg tctagtgctt gatttttatc gtatgaaata ggtcgcgtag tcatttgacg
    12181 ttaaccttag ctatttttaa aatagaaatt gagaatatga actattgaaa gatcggagca
    12241 atccggtctt tttatataaa gaaattgcat ataatactca tctgctttca aaaagtattc
    12301 tagtccatct ctgattaacg atggacttta tcacctcctt ctccagtcct tgtatgacat
    12361 cttggagttg attcatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt
    12421 tatgaatctc tttccacact tgttcgatgg gttcatctct ggtgtgtatg gaggaataaa
    12481 tgcaaaacca atattagtcg gagtctttat aagatttgcc catcagacga aatagaatga
    12541 tttgaaggca tttatgatat ttagctgtac gagagtcttt aaaaagtgtt ttgatggttt
    12601 ggatttcttc tttagttgat ttcatatcac tattatataa tgctttttga ttttagtata
    12661 gtattatcgt agaaaatgga ctcggtgcta tggatacacc ggatgagaat ggttatgtag
    12721 cagatgacta ccggattact tacttagagg cccacatcaa ggccatgcga gatgccattt
    12781 acaaagacgg ggttgacttg cttggttata cgacatgggg ctgtatcgat tcggtttcag
    12841 ctggcacagg ggaaatgaat aagcgctatg gctttatcta tgtagatcga gataatgtag
    12901 gaaatgggac tctcaaacgt agcaagaaga agtccttcta ttggtacatg tcatttatag
    12961 caatggtgta agcatcgagt agagcacatt tgtttactat ttttataaaa tcttctccct
    13021 gctttataag atgtaaaaaa gagttcaaat ggaactcttt ttttgctata atgaggggag
    13081 aaaaatcaga caggagatta agatgtcaga accattattt ttacaatcag ttatgcaaga
    13141 aaaaatctgg ggtggtacca agctacgtga tgagtttggc tacgacatcc caagtgaaaa
    13201 agtcggagag tactgggcta tctcagctca tctaaatggt gtttctaaag ttgccaatgg
    13261 tcgttacgag ggaacagatc ttgctacttt gtatgcggaa caccgtgaat tatttggcaa
    13321 tcgtcctgag cctgtatttc cgcttttgac taagattttg gatgctaacg actggctcag
    13381 tgttcaagtt cacccagacg atgcttatgg actagagcat gaaggcgaac ttggaaaaac
    13441 agaatgctgg tacatcatcg ctgcggatga aggttcagag attatctacg gccacaatgc
    13501 caagtcaaaa gaagaactcc gccagcaaat cgaggacaag aactgggata ccttgcttac
    13561 caaagtccct gtcaaggctg gagatttctt ctatgtacca agtggcacca tgcatgctat
    13621 cggtactggc atcttgattc ttgaaaccca acagtctagt gatacaactt accgcgtcta
    13681 tgactttgac cgaaaggacg ataagggcaa cttgcgtgaa cttcaccttg aaaaatccat
    13741 cgatgttttg aacattggcg agccagcaaa tagccgtcct gtaactgtta aagcagataa
    13801 tttgcgttcc actttacttg tttctaatga tttcttcgca gtttacaagt gggaaatcac
    13861 tggaaaagtt gattttgaga agacagctga ttacagtttg tttagtattt tagctggcca
    13921 aggtcaactg actgttgatg gaaaaaacta tccaatccaa aaagggagcc actttatcct
    13981 accaagtgat gttgaatctt ggactttaga agggcaagat ttagaattaa ttgttagtca
    14041 tccataaaaa agaaagggcc tgagttcatt actcaagtcc ttttgattac ataaattggg
    14101 cgatgaagac cacgatgatg attggaatga cgaaacgaag aaggaagagc cagacttgga
    14161 acagtccttg tttccatgct ctttcatcga gatggagttc ctccattgca agagcctttt
    14221 taaagatata gcctgtaaaa agtgaaaggc agagagctcc aaatggcatg agaagattgg
    14281 aaaccaagaa atccatggca tcaaagaaag ttttaccaaa gatgtgaaca tccgccataa
    14341 ctccatagga tagggctgaa ggaatgccaa agacaaaggt caaaattcct aaaataacac
    14401 tccatttggc acgtttgctg ttgtcctgat tggtgatatt gtctacattg atttccagca
    14461 taacgacaga agaagtgaca gtcgcaaaga ggaagaggac atagaaaatg gttccaaaag
    14521 gcatcttgtc aaagagttga ggcaagacga taaagaccaa gctcggtccc ccttcagact
    14581 ggatattgaa gggggaccga gcttggaaaa tggctagacc tgccatgatg gataccgaga
    14641 tattcatggc tacgatggag attcttgact ggaccagatt ggttttcttg tccaagtaag
    14701 aagcataggt caacatggct gtaaccccta gtgagagggc aaagaaagat tgtctcagag
    14761 catagaggag accagcgcta gtcagttttg aaaagtctgg tttgaggaag taaagaaccc
    14821 cttccatggc atttgacaag ctgagagagc gaccgatgat aacaacaaag atgataaaga
    14881 gcaggggcat catgactttc gaagctcttt caatcccttt ttgaacccca cgtgatacaa
    14941 tgaagatatt caataggata aaggccgctt gagctcctag ggcaatggct ggatttgaaa
    15001 tgatcagact tcctgcgaaa caaaatatgg tatagtagtt ctatgaatga tgaagcaagt
    15061 aaacaactaa ctgatgcacg atttaagcgt cttgttggtg ttcagcgtac cacttttgaa
    15121 gagatgttag ctgtattaaa aacagcttat caacttaaac acgcaaaagg tggacgaaaa
    15181 cctaaattaa gcctagaaga ccttcttatg cccactcttc aatagtgcga gaatatcgaa
    15241 cta
//
LOCUS       DAVKXA010000049        15208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKXA010000049 DAVKXA010000000
VERSION     DAVKXA010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.049"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            83..880
                     /locus_tag="VW883_001701"
     CDS             83..880
                     /locus_tag="VW883_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0274802.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VW883_001702"
     CDS             1028..1150
                     /locus_tag="VW883_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV0274803.1"
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1172..2212
                     /locus_tag="VW883_001703"
     CDS             1172..2212
                     /locus_tag="VW883_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0274804.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDHLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2383..3657
                     /locus_tag="VW883_001704"
     CDS             2383..3657
                     /locus_tag="VW883_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0274805.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VW883_001705"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VW883_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0274806.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VW883_001706"
     CDS             4786..5088
                     /locus_tag="VW883_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0274807.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VW883_001707"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VW883_001707"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0274808.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VW883_001708"
     CDS             5962..7302
                     /locus_tag="VW883_001708"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0274809.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLIIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VW883_001709"
     CDS             7280..7492
                     /locus_tag="VW883_001709"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0274810.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VW883_001710"
     CDS             7489..8364
                     /locus_tag="VW883_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0274811.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VW883_001711"
     CDS             8357..9172
                     /locus_tag="VW883_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0274812.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VW883_001712"
     CDS             9165..9596
                     /locus_tag="VW883_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0274813.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRY
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VW883_001713"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VW883_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0274814.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEADIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VW883_001714"
     CDS             11272..12000
                     /locus_tag="VW883_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0274815.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRSEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VW883_001715"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VW883_001715"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0274816.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14061..14141)
                     /locus_tag="VW883_001716"
                     /pseudo
     CDS             complement(14061..14141)
                     /locus_tag="VW883_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14317..14793
                     /locus_tag="VW883_001717"
     CDS             14317..14793
                     /locus_tag="VW883_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0274817.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEAIA"
     gene            14831..15133
                     /locus_tag="VW883_001718"
     CDS             14831..15133
                     /locus_tag="VW883_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0274818.1"
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGSILFRIPAMSAPVFDNIILPAKQNMV"
BASE COUNT         4547 a         2758 c         3567 g         4336 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa acctcttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaagat gtcggttcaa tctttacctt
     2041 ccatgtcaaa ggtggcgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaact aaattcgttt
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg cttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaaa gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataaggattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggccgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagccacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc agttgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagacttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gatcatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttt ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt ggtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acaaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttga tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgatatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgtaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtattg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaca
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattttt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagaag tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttattca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataaaaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aactgtgttt tgaacaacct
    14101 gcggctagct tcctagtttg ctctttgatt ttcattgagt attagaacag aaaaaatgct
    14161 tggagtattt gtttgtgtgt ttacttttat ataacaaact ataaacacaa caaaaatata
    14221 aaaaaagaga caaaaaaaga acagaaagta attaacaacg atttcatata gtgttatact
    14281 tatagcataa agttaatgga aagaagggaa aaccttatgg tattagatta tttctttgac
    14341 aaaaaccttg tgttttgctt agaagcggat aatcaagaac aactctttga tcaggtagca
    14401 agcttgttgg aagaacgaga aattgtcact ccaacttatc gtgaagcctt gatcacgcgt
    14461 gaaaagtcat ttccaactgg tttagatatg gaatttctag gaaaggactt gccaaatgta
    14521 gcgattcctc acacagatat tgttcataat ctagctgaaa aagtggtggt tgttcgatta
    14581 gaaaaaccag taacttttca caatatgata gctcctgata aggaagtaga agtatcccta
    14641 ctcttcttta tcattaacaa ttcaagttca agtcaaacaa atattctggc tcagttgatg
    14701 gactttttca caggaaatgg acatcttgaa gatttatcaa aaatttccga accagaaaaa
    14761 ctttatgctt acattgctga agcaatcgct taatcttgtc tattaaaaaa taaaatcgga
    14821 ggaaatccaa atgattaaaa ttcttgctgc ctgcggtgca ggtgttaact caagttacca
    14881 aattaaaagt gctctagaag aagaactttc aaaccgtggt tatgatgttc actgtgatgc
    14941 agtcatggtg aaagatgtaa acgaagacct tatgaaaggt tacgatatct ttacaccaat
    15001 cgctgcaaca gatcttggtt ttgaaccagg tatcccagtt atcgaagctg ggtcaatctt
    15061 attccgtata ccagcaatga gcgctccagt atttgacaat attatacttc ctgcgaaaca
    15121 aaatatggta tagtagttct atgaatgatg aagcaagtaa acaactaact gatgcacgat
    15181 ttaagcgtct tgttggtgtt cagcgtac
//
LOCUS       DAVKXA010000050        14073 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKXA010000050 DAVKXA010000000
VERSION     DAVKXA010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.050"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(123..1319)
                     /gene="tuf"
                     /locus_tag="VW883_001719"
     CDS             complement(123..1319)
                     /gene="tuf"
                     /locus_tag="VW883_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0274819.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2241..3110)
                     /locus_tag="VW883_001720"
     CDS             complement(2241..3110)
                     /locus_tag="VW883_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0274820.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3333..4010)
                     /locus_tag="VW883_001721"
     CDS             complement(3333..4010)
                     /locus_tag="VW883_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0274821.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGFF
                     KKKEDEK"
     gene            complement(3982..5073)
                     /locus_tag="VW883_001722"
     CDS             complement(3982..5073)
                     /locus_tag="VW883_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0274822.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSKGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTIITVRMLRKSGSQNSNLY"
     gene            complement(5184..5438)
                     /locus_tag="VW883_001723"
     CDS             complement(5184..5438)
                     /locus_tag="VW883_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274823.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5778..6224)
                     /locus_tag="VW883_001724"
     CDS             complement(5778..6224)
                     /locus_tag="VW883_001724"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274824.1"
                     /translation="MDETGIDRYLYRPYARAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNASFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDVLREVSTIFECLECFFKTR"
     gene            complement(6297..6623)
                     /locus_tag="VW883_001725"
     CDS             complement(6297..6623)
                     /locus_tag="VW883_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274825.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            6857..8575
                     /locus_tag="VW883_001726"
     CDS             6857..8575
                     /locus_tag="VW883_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0274826.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8686..9033
                     /locus_tag="VW883_001727"
     CDS             8686..9033
                     /locus_tag="VW883_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0274827.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9312..10148)
                     /locus_tag="VW883_001728"
     CDS             complement(9312..10148)
                     /locus_tag="VW883_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0274828.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10161..10790)
                     /locus_tag="VW883_001729"
     CDS             complement(10161..10790)
                     /locus_tag="VW883_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0274829.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(10800..11441)
                     /locus_tag="VW883_001730"
     CDS             complement(10800..11441)
                     /locus_tag="VW883_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0274830.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11587..12816)
                     /locus_tag="VW883_001731"
     CDS             complement(11587..12816)
                     /locus_tag="VW883_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0274831.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLKQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(12806..13972)
                     /locus_tag="VW883_001732"
     CDS             complement(12806..13972)
                     /locus_tag="VW883_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0274832.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKINRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
BASE COUNT         4206 a         2979 c         2547 g         4341 t
ORIGIN      
        1 tattatagtt tgctctttga ttttcattga gtattagttc aatatctaaa aaaagaacct
       61 tgccaagcaa gattctttta gtgtctgact taaataattg ttcttctggg aactaaatcg
      121 aattaagctt cgatttctgt aaccatacct gaaccaacag tacgtccacc ctcacggata
      181 gagaatgtag taccttgttc tacggcgatt gggtgaatca actcaacgtc gattgtcacg
      241 ttatcaccag gcattaccat ttcagtacct gctggaagtt cgattgaacc tgtaacgtca
      301 gtagtacgga agtagaattg tggacggtag ttgttgaaga atggagtgtg acgtccacct
      361 tcttctttag taaggatgta gacttcacct ttgaatttag tgtgtgggtt gattgaacct
      421 ggtttagcga taacttgtcc acgttcgatt tcatcacgtt gaacaccacg aagaaggaca
      481 cctacgttat ctccagcaag accttcgtca agttgtttac ggaacatttc aacaccagta
      541 acaactgctt tttgagtttc ttctttgata ccaacgattt cgatttcgtc gttgacttta
      601 acgataccac ggtcgatacg tcctgaagca actgtaccac gtccagtgat tgagaatacg
      661 tcctcgactg gaagaagcaa tggtttgtca gtgtcacgtt ctggttctgg gatatactca
      721 tcaactgtgt tcatcaattc cataacgatg tcttcgtatt tagagtcacc ttcaagagct
      781 ttaagtgctg aaccttggat aactggaaga tcgtcacctg ggaagtcgta ttctgacaat
      841 aggtcacgga tttccatttc aaccaattca agcaattctt cgtcgtcaac caagtcaact
      901 ttgttcatga agacgataag gtgtttaaca ccaacctgac gtgaaagaag gatgtgctca
      961 cgagtttgtg gcattggtcc gtcagttgaa gctactacaa ggatagctcc gtccatttga
     1021 gcagcaccag tgatcatgtt tttaacgtag tccgcgtgtc ctggagcgtc gatgtgagcg
     1081 tagtgacgtt tttcagtttc gtactcaacg tgcgcagtgt tgatagtgat accgcgttcg
     1141 cgttcttctg gagcagcatc gatagacgca tagtctttag gttggttaac tgatgaaggc
     1201 aagcgacgtg ccaaaacagt tgtgatagct gcagttaggg tagttttacc gtggtcaacg
     1261 tgtccgatag taccaatgtt aacgtgtggt ttactacgat cgtatttttc ttttgccatt
     1321 tgagtaaaag cctccaataa aatatatttt atagatagac agtaggcaat acagtctaac
     1381 tttccttact attttatcaa atttcagcta aattgcaagt gttttacaat gtttttgtga
     1441 attattcttg gtaaaaattt aactaattaa tagaaagtac taaatagact tatccttcaa
     1501 ggagttttca gcattatcca tccactcact tgctgaaaat gtaaacagtc tctggtttat
     1561 atagtaaaat gaaacaagaa tagagcaaat cgatcaggac agtcaaatcg atttctaaca
     1621 atgttttaga agtagatgtg tactattcta gtttcaatct actatacaac ctcaaaactg
     1681 tgttttgaac aacctgcggc tagcttctta gtttgccctt tgattttcat tgagtataaa
     1741 attgcagata aaacgataac aatcatagga ctcagcagag tcaatgtagg tcgaagaata
     1801 gcccccctaa tcgcttattt tatagcaaaa tgaaatagaa actgaacatt ttgttgagga
     1861 aggtaaatca attcctcaca atgtttgaga aagaaggggg gactattcca acttcaaccc
     1921 actataaagc agacttacaa gatagggaac ccatctccga taatatatag tagaatgaaa
     1981 actgcacaat ttgattggag aattcaaacc aatttctaac aatgttttag aaacaagggt
     2041 ctattatttc aactgcaacc tactatagcc cattgaagct ggaatagccc actgagactt
     2101 ctaaaccact gctggagagg agtttgttta gagtttgttt agagtttctt tcatttccct
     2161 aaaaaatcaa aaagagagaa ccagtctgat cctctcttac ttatagatgg tgctcactca
     2221 aatgttaaag gagctatttc ttagagataa aggaatttga atacagctac tgccgcaatt
     2281 gctgctgcga taggtgctac tactggtacc caagaatacc accattttga atcgccttta
     2341 tgctcaccaa gaactgattt tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg
     2401 gctgggttca aggcaggtcc tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg
     2461 aatccaagtg ccaagtgagc cacagaaagt cctgaagcag tgtgtggagc cacctgtgct
     2521 ttaatagcca agtcagaaaa atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg
     2581 aattgaagca cttcagcacc aaagaagttt ttagtcaaac caagagctgc aaagaacaaa
     2641 acaaatgaac caacaaattc attaatcaaa ccattgacag ttgctgcata gcgactttct
     2701 tttgtaccat ggtcaatact tgaaatagtt gagaaagttc ccaagatgtt atttgggttt
     2761 tcagttttca agtagaatgg acggtatgtt gccacaacta aggcttggcc aaagatagcc
     2821 cccaagactt gcgcgataat gtaaggtacc acttgtgccc aagggaaaag accgctaact
     2881 gcaagcccta gagtgaaagc agggttgatg tgattcccag atacgttacc aaacatcaag
     2941 gcagggatca taacccccat accataacca acagcgatga cgatccagcc actttggtga
     3001 cctttcgtac ctttaagttc aacgttggca actgcaccat tcccaagaat gatcaaaatg
     3061 gcagttccca aaaattcagt ggcatacttc agtgcccatg tgaaatccat ttgctagatt
     3121 ctccttaaaa ttttttagat attccttatt ttatcaattt ttaccctatt tagcaactga
     3181 tttctggaaa tatttttaaa aaaataggat tcatagtttc ccagttcaac gtacttgtaa
     3241 gcgtttttat tcttcacgaa agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg
     3301 atcttttcct tgttcctaga ttctaaaatc tattattttt catcttcttt tttcttgaag
     3361 aatcctaatc ctagaccagc taacaaggtc atgataccag cactagccaa ggtagcatta
     3421 gcttctgtac ctgtgtttgg caattcctct ctcttacctg tctcataagt cggaacttct
     3481 gggtctggat tcactggagt ttcagttttt ggagtacctg gttctggagt tggctctggt
     3541 attggagtct cttgatttgg tagttctggg tttggtgtcg gaacacttgg atgctctgga
     3601 tttggttgtg ggattggttt ttctggagtc ggttcacctg gagtacctgg ttcctgagga
     3661 cttggaattt ctggtttttc tggagttggt ttatctggtg ttgataaacg gtcatacctt
     3721 accgttattt ctttatcact agagtctgac gtaacttctt gtgattcaac tgttggaata
     3781 tctggatctt tgtacttgtc aatcttacca gatacaacct cgtcccagtt tcctgttgtc
     3841 cattcaccgt aggttacaac tcccgtgacc ttgttctcag tttttgtacg gcttaaggtt
     3901 acaggttgaa caacatcttc ttttacattt tggttcgtaa ctttatcaac gtaatgaatg
     3961 atacgcgtta tagtcttcgt ctcagtagag gttgctgttt tgggaaccac ttttcctcaa
     4021 cattctcacg gtaataatag tcaactgttg caccgtcttc tggtacgcat ttgcaggagt
     4081 tgctaccaag gtgtatgttg ttttccttgt gataactcgg tcttctttgt cctcagttgt
     4141 tgttttccct tcaatagttt ttgattctgt ggtatactca gaacctatcg ctaaatcagc
     4201 ttttataaca gactctgcca acttctcttg gctaccttct ttatagtaat tggctgttac
     4261 tgtagcagtg gttggcgctt cgctttctct ataaactaag gtcactgttc tacctttgct
     4321 tacaatattc ccagttaaac ttgcagaatt tgtatctact tctttaaaag tataatattt
     4381 tccgtcagta gtagtcatgc tactgagttt tttatctgtg acattatagc tggtaccaat
     4441 cagttgtttt ttattggtaa tgtaggttcc gtcactttct ttttctccaa ttccagtatc
     4501 atttttcaat gatagcaaac gcccttgttc atcaacatag cgaactttca cattttctga
     4561 gattagttct gccaattctg aggttttttt ctttttcttg atttcttcgg ttattttccc
     4621 tttctcttct tcgggaatat ttagttttgg aatgattttt tcaacaacgg ttcgtgatgg
     4681 ttccacagta tcttggatga ctgaaaagtc agctagaatt gggagattat actgaacacg
     4741 gtgactttga gtgtttactc ctactctttc attattctct gaaaatactt gtacggtata
     4801 agaaacaaca tcttttccta atagaacatc cccagtagag aaatagccgc cttttcctag
     4861 tttgctatct ccagagccca cttctttcct aatcttatca gatagttttt taccagtcag
     4921 tacattcgtt cgcacaatcc ctttgtctac ccctacaaag tgggagaatt ttttgaactc
     4981 ttcagaacca gatctagccc aaccattatt aagggcattt gcttttgtat ttgtattctc
     5041 tctcaaaggt ttggcgatta gaattatatt catcggcgct tagagttgct gctatatctg
     5101 actcttgaat accaacttcc ttactaccat ttctagcggc agtatatgtg tatttatctg
     5161 tttctacttc tagctgatta tccttaacat gataggtaat tttctcctgg tataagagtc
     5221 ttcagtagtt tatatgctct gtcatcatct ttagctttag aagcagctga gtttagccaa
     5281 gttggggtat taggagtatc tttatcagcc tgtttcaaga cattattcaa gtcatttgct
     5341 agcctattgg ttatcctcac tgtgaaagtt ttcttccagt ctgaaccact tttattagac
     5401 ttagatatgc tcatgaaatc ctggtcaaca ttcaacacaa tatcgcctta ttttttagca
     5461 tcttccgttg cttctgcttc aaattgatca tggagttttt gttgctctgg tgtatagttt
     5521 ttttatttac acgatttaat gtactatttt ttattttagt attaagaact ccattaatac
     5581 gatttttaaa ctctgcttca aaaaatccct taatttgttg gtgcgcaagt tcaacattca
     5641 aacctttctt atacaagtct tcattctgaa cgatttcggc tacacggtga atggtttgat
     5701 cgtataccgt cttctcttaa ccagcagtat ccttagtttt aatgactact cgataggttc
     5761 ctttagaacc gttatagtca tctagtttta aaaaagcatt ccaaacattc aaaaatagtt
     5821 gaaacttccc ttaatacatc cgtcactttc tttttcaaga tagcccaagc ttgctcaata
     5881 ggattcaaat ctggtgaata aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag
     5941 agttcatcca aaatgttctt gggatgaaaa ctagcattgc ccatgacaat aacatgaggt
     6001 gtcttcaaag caggtaggag ttgcgttttg aaccactcca caaagaaatc gcttgtcatg
     6061 cttttcttgt aaatcatggg agctataaac tctccgtcta cttgtcctgc aacaattgaa
     6121 gttcgctcaa aacgacgtcc gctaatcttt tcatagactt tctcccctct aggagcccgt
     6181 gcataaggac gatagagata gcggtcgatt cctgtttcat caatataaac aggtgctagg
     6241 tgctttaaac tattaaaatt cttaagaaat aaggctactt ttctgggtct tgttccttaa
     6301 agatcgtcat ctttttttaa agtgacctta atctgcttta aagctgccca tactgaagga
     6361 acagcacaat caaaatgtgc cgcaatttcc cgtaaaaaag catctggatg agcctctaca
     6421 aaggctttca attcttctaa agggatctta cgctttttga cgactcgctt tttccgctct
     6481 aagttccttt gttcacgtct ttcttttccc acgtgaagag agttctgacg ccaacaccaa
     6541 aaaactttgg ccgcctcgac atgtctgtgc cctcctttga tggaatctaa tgctccttgt
     6601 ttaaaatcag tattatatgc catagcttta ttagaccatg cttattttaa actaagcaac
     6661 tatatcaatg ttttgttatg agaagactta ctttttttac tgaaattgaa tttttcctag
     6721 cctcaacatc atataacccc aaaattcaat ctgacctggt ttgaatagat gttcgaagca
     6781 gataaggttt tactaaaact aaaaaaaatg atataatcaa attgattaaa tgttttaaaa
     6841 ataaaggaga atttgaatgt cttaccaaga aaattaccag aaatgggttg attttgtgga
     6901 gcttcctgac taccttcgtc aagatttgga aaatatggac gaaaaaacta aggaagatgc
     6961 cttctataca aatcttgaat ttggtactgc aggtatgcgt ggcttggttg gtgctggtac
     7021 aaaccgtatc aacatctacg ttgttcgcca agctactgaa ggattggctc gtttgattga
     7081 gtcaaaaggt ggaaacgaga aagaacgcgg tgtagcaatt gcctacgata gccgtcactt
     7141 ctcacctgag tttgcctttg aatctgcggc agttcttgct aaacacggca tcaaatctta
     7201 cgtatttgaa agccttcgtc cgactccaga actatcattt gcagttcgtc atctcaactg
     7261 tttcgcaggt atcatggtca cagccagcca caaccctgct ccatttaacg gttacaaggt
     7321 ttacggtgaa gacggtggac aaatgcctcc acacgatgcg gacgctttga ctacttatat
     7381 ccgtgcaatc gaaaacccat ttgcagttga agttgctgat gtggaaactg aaaaagcttc
     7441 tggcttgatt gaagttatcg gcgaagctgt tgacgtagaa taccttaaag aggttaagga
     7501 cgtaaacatc aacccagcct tgattgaaga atttggtaaa gacatgaaga ttgtctacac
     7561 accacttcat ggtactggtg aaatgttggc tcgtcgtgct cttgcccaag caggatttga
     7621 ctctgttcaa gttgttgaag cgcaagcaac tgctgaccca gacttctcaa ctgtaacatc
     7681 tccaaaccca gaaagccaag cagcctttgc ccttgctgaa gaacttggtc gtcaagttgg
     7741 tgcagatgtt cttgtcgcaa ctgacccaga cgctgaccgt gttggtgttg aagttcttca
     7801 aaaagatggt agctacctca acctttcagg taaccaaatc ggtgctatca tggctaaata
     7861 catcttggaa gctcacaaaa acgctggaac tcttcctgaa aatgccgctc tctgcaaatc
     7921 tatcgtttca actgacttgg taacgaagat tgctgaaagc tacggcgcaa ctatgttcaa
     7981 cgtcttgaca ggtttcaaat ttatcgctga aaaaatccaa gaattcgaag aaaaacacaa
     8041 ccacacttac atgatgggat ttgaagaaag cttcggttac ttgattaaac catttgtacg
     8101 tgataaagat gccatccaag ccgttcttgt cgttgctgaa cttgctgcct actaccgttc
     8161 tcgtggtttg acacttgctg acggtatcga agaaatctat aaagaatatg gctactacgc
     8221 agaaaaaaca atctctgtta ctctttcagg tgtcgatggt gctgaacaaa tcaaagcgat
     8281 tatggctaaa ttccgcaaca atgctccaaa agaatggaac gcaacagcta tcactgtcgt
     8341 agaagacttc aaggcacaaa ctgctactgt tgctgacggt actgttacaa acttgacaac
     8401 tcctccaagt gatgtgttga aatacacact tgctgacggt tcatggattg ccgttcgccc
     8461 ttcaggtaca gaaccaaaaa tcaagttcta cattgcagtt gtaggggaaa ccaacgaaga
     8521 atcgcaagct aagattgcta acatcgaagc agaaatcaat gcatttgtaa aataaagacc
     8581 tataaaagat gagaccaacc aacctcatct tttttcgtat caaatctaag caattttaga
     8641 aactttatgg catactagac ttatcaatga aagcgaggta atctcatgga acaattttta
     8701 gataacatca aagaccttga agtcactaca gttgtgcgtg cacaagaagc tcttgataaa
     8761 aaagaaactg caaccttctt tatcggtcgc aaaacttgcc cttactgccg taaatttgca
     8821 ggtacattgt caggtgtcgt agctgaaacc aaagctcaca tttacttcat caatagtgaa
     8881 gaaccaagcc aactcaatga tttgcaagca ttccgctcac gctatggaat cccaactgta
     8941 ccaggttttg ttcatattac agatggacaa atcaacgtcc gttgcgactc ttcaatgtca
     9001 gcacaagaaa tcaaagattt cgcaggattg taaaaaatca gctaacaagt cttaaaatca
     9061 caaaaacgca taatgtaagg tgcaaaaacc ttgatattat gcgttttatt gttcctaaaa
     9121 cagttacatc agcatttcat tacagaacat tttaattttg gaagtcaaat caatttttaa
     9181 caatgtttta gaaatcacag tgggctattc catattcaat tatccagatt caatcgctat
     9241 tatcgttttc ctagattaca aaaaaaactg cgttttgcta atcaaaacgc agtttcagcc
     9301 actattttat cttactgtcc ttcttttact tctttggttg ctacatcttc tccaaaccat
     9361 ttttggctga tttcttggaa cttgccgtcc ttgtaaagac tagaaaaagc ttcatttatc
     9421 ttcttaacca aggttgtatc ttccttacgg gctccaaccg caaaagcttc tgtttctagt
     9481 ccaactgtaa agacattata atcgtttaaa acaccttctg cttctaaata atagtttgca
     9541 tagacacggt caatcaatag accatcaatt cgatcgtttt tcaaatcaat caaggcttca
     9601 ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa tattcttcaa aatttctgga
     9661 tttgcttcaa agtccgcata accagatgaa ccagcttgag ctcctaatgt ctttccagtc
     9721 atatcctttg cagtcgtgat accagatgat ttcttcgtaa ccaatacctg ctcattcttc
     9781 atatatgagt tactgaaagc caccttttca cggcgttcgt ctgtagcgga atagccattc
     9841 caaatcagat caatcgttcc ttttgtcaat tcagcttctt tcaaatccca atcaatcggt
     9901 tgccaattta ccgtgattcc gtatttttca aaaacagctg tagctaaatc aatatcaaat
     9961 cctgcataag aaccatcttt ctgagcaaat cccattggaa caaaagtact atcaaatcca
    10021 atagtaatag acttgttaga ctggtacttt gaccaattat ctccactagt ttcgctagaa
    10081 tttttcccac aagctactaa gaacaaagca gtcatcagac tgactaatac aagcatccat
    10141 tttttcatcc atttttcctc ctatttaggt tctactttca ataatacatc tgcgatattt
    10201 tcagcaaact gcaaatcatg ggtaaccaca atctgggtca tcccaagttc cctattttgc
    10261 aagattagct tctccacttc caaacgcaat tctggatcca gggcagaagt tggttcatcg
    10321 tagccaatga tttctgggtc aatcatcata gcacgcgcca aagccacccg ctgcttttgc
    10381 ccaccagata gtgagaaagg ataggcctct gcgtgtcctc ctagtcctaa ctgttccaag
    10441 agtccactcg ccttcttctc agcctcttcc tgcttcattc ccatggtctt cacaggcgat
    10501 aaagtcaaat tttccagaac tgatagatga ggaaatagtt gaaaatcttg gaagacaaat
    10561 cccagtaggt tgcgcttctg caattcatcc agctctaaag gttgtccatt ataaaagatt
    10621 tgccctgaat caatggtttc aagacccgca agcatacgta aaagagtcgt cttacctcca
    10681 ccagaaggtc caacgatagc caggatttgc ttttcaggaa tacttagact gaaattagac
    10741 aggatttgtt tgtctccaaa gactttattg atatttcgta attctaacat ggcagcctcc
    10801 tatctataat aactatactt cttctcaact tttttggaaa taattgtcac aatcccaatc
    10861 aaaatcaaat aaatggctcc tgccaagaac ataggaacta gactagcatc gcggttagca
    10921 gctgttcgac tagccaagat aaggtctgaa attccgagag catagaccaa agaagtatcc
    10981 ttgaccaaac tcataacttc attaaagaca ctaggaagaa cgatcttggt cacttggggc
    11041 aagataatat agcgcactct gtcaaaaggg ctaaacttca agaccttggc agcctcatac
    11101 tgtcctcttg gaatagtgtc aattccccca cggaaaattt ctgcaaagta agctgcatag
    11161 ttgagaacaa aggcaataat agctgcagga aggcggtcta aacgaatccc aatacttggg
    11221 agcacataat agataaaaat cagttgcaag agtaaggggg ttcctcgcat aacccagatg
    11281 taaatgttaa tcagataatg gaggggcttc caatggactt gcaaggcaaa ggcaatcaaa
    11341 acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga cctgtacagt cgtgctcgca
    11401 ccattcagta aactcggtaa tatctcaaat aaataagaca tactgcacct cctaaaagta
    11461 attgttccta ttatagcatg aataaacaag attaccaagt atttttgtaa aaagattcta
    11521 ccatatacaa ataaaaaccg tagctatcaa aagagataaa ctacagttct atatgtttaa
    11581 acattcttac aatctctcaa acagttcttg catttgcaca tcatctggaa ccagttttaa
    11641 gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc aattcacgca agagatagat
    11701 atagtgttcc agaaattctg gattgtcctt caaatctcct gtcaactctt gataatgctc
    11761 ataagcagta tccaaatcgt ccatttcttg ataagaacga gcaatcatcc acttggtcaa
    11821 aagattttct ggctcctcac tctgcaagtc tagaatatcc tcataacgct cctgcttcag
    11881 ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc tcagcgtctt cttttgcagc
    11941 aagaagataa ttttctgcac cactagcatc atgcaattca taagaaaatt gtgaagcagc
    12001 tagcaagagg cgagtttcaa agggattttt ctctaatcct tgcttagcga tacgcagggc
    12061 ttcttgaact tgatgttcct tatgtaaagc ctgactgtac ccatactcat agccttcaaa
    12121 gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg gctttttgat attcttcttg
    12181 atcaaaataa agactggcca actcaaaagc tgttaagtca tcgtattcta actccagggc
    12241 tttttctaaa aactcagtag ccgtttcaaa tttccctaac tgagcatagg caaagccaat
    12301 tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag cgattatcta actgggcata
    12361 agcttgaata gccgcttggt aattttccaa ctcactatcc aactctgcca aacccaacat
    12421 caagagagaa tcctctgagt aggtcaaggc ctccaataat ttctcacgtg ccacatctgt
    12481 caaaccttcc agctggtaaa ggtctgcctt cagagccaaa gacgagacat accagtcact
    12541 atcagcttgg atttcctcaa gataggtaaa ggcttcttct atttgaccat cctcgctagc
    12601 aattgcagct agattaagat gaacctctgg aaaatcctct acaattttca ggtaaatttc
    12661 cttggcctga ggatagaaac caatcccttc aagataagtt gccaactcat acagaagatc
    12721 acttgaatca ttttctaaag ctttggcgaa ataatgctca gccttagtta aatcttgctc
    12781 ctccaaagcc tgtaacatct gttgactatt gttcactctt gacttcctca ccctctaatt
    12841 catatagacc actgactacc ttataccatt cgaaaatggc tgaaatgaca accttagcag
    12901 aggcataaac cggaatacca agtaaaactc cccagatacc aaacatagat cctgaagtta
    12961 acaaaacaaa gagaacatta atagggtgga tgtttaattg acttcccaaa atcaatggag
    13021 agacaaaacg gccttcaata gtttgttcta caataaagac aatcactact ttcaaaagca
    13081 tgactggacc agcaatcaaa cccaatacta gggcaggaag catggctaga aagctaccaa
    13141 gataagggac cagatttaaa ataccagcag taacccccag cgtaaccgca tagcgtagac
    13201 caataatctt gaagaagatg ataaacatta ctgctacaat aatagccact gtcacttgcc
    13261 ctcgaacata gttggacaac tgttgattca catctgatag aacttgtcca acaggttcct
    13321 tcaattttct tggaatgaat tgggtcaaat agttacgcaa gcctttccca tcacgcaaga
    13381 gataaaagag catgaaagga acgataatca aggcaacaat cacttgagaa gctccgctaa
    13441 taaaggcact cacccagttg actgcctgag atgaaacctt acttgccaaa actgtagcct
    13501 ggctagaaaa attggtcaaa acttgctcta attgaggtct gaaatcatct ggcaggtgct
    13561 gggctaccaa tccattaaca atcctatcta tatcttctaa gtaaacagga acgtttcttg
    13621 caaaggtcaa aacctgacgt tgcagatttg gaatggcgac tgccaagccc caaatgataa
    13681 agagagcgat gataacaaag acaatagtga tagctataac acgattaatc ttatgcttct
    13741 ccatccaatc aacaatagga ttcaacaaat aatataacaa accagacaaa atgactggca
    13801 acatcacaac tgctaaaaag tctaaaacag gtgaaaatag aaaactaatc ttacttaaaa
    13861 taaaaagatt cagtcccaat aataaggtta ctaaaaatac cgtaattgcc ttgttatcta
    13921 aaaaccactt gaaaaaccaa gataggctaa aatgtttctc tttttgctcc ataaatactt
    13981 cctttctatt gttctctcat tataccattt ttaaaacaaa ataactcttt tttaaagtgc
    14041 ttacatctaa ttggatatct ttaatttact tgt
//
LOCUS       DAVKXA010000051        13819 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKXA010000051 DAVKXA010000000
VERSION     DAVKXA010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13819
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.051"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(20..2179)
                     /locus_tag="VW883_001733"
     CDS             complement(20..2179)
                     /locus_tag="VW883_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEV0274833.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(2176..2772)
                     /gene="recU"
                     /locus_tag="VW883_001734"
     CDS             complement(2176..2772)
                     /gene="recU"
                     /locus_tag="VW883_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0274834.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            2838..3365
                     /locus_tag="VW883_001735"
     CDS             2838..3365
                     /locus_tag="VW883_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0274835.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            3435..3764
                     /gene="gpsB"
                     /locus_tag="VW883_001736"
     CDS             3435..3764
                     /gene="gpsB"
                     /locus_tag="VW883_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0274836.1"
                     /translation="MASIIFSAKDIFDQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            3785..4165
                     /gene="rnpB"
                     /locus_tag="VW883_001737"
     ncRNA           3785..4165
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VW883_001737"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4250..5407
                     /locus_tag="VW883_001738"
     CDS             4250..5407
                     /locus_tag="VW883_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0274837.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            5420..6814
                     /gene="mapZ"
                     /locus_tag="VW883_001739"
     CDS             5420..6814
                     /gene="mapZ"
                     /locus_tag="VW883_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0274838.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVEIQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDANAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            6890..8314
                     /gene="gndA"
                     /locus_tag="VW883_001740"
     CDS             6890..8314
                     /gene="gndA"
                     /locus_tag="VW883_001740"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0274839.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPATFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            8326..9015
                     /locus_tag="VW883_001741"
     CDS             8326..9015
                     /locus_tag="VW883_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274840.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            9113..10135
                     /gene="cbpC"
                     /locus_tag="VW883_001742"
     CDS             9113..10135
                     /gene="cbpC"
                     /locus_tag="VW883_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0274841.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQNLGNNWYYLRSSG
                     AMVTGWYQDGSTWYYLDAENGDMKIGWTKVNGKWYYLNSSGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            10154..11152
                     /gene="cbpJ"
                     /locus_tag="VW883_001743"
     CDS             10154..11152
                     /gene="cbpJ"
                     /locus_tag="VW883_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0274842.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKDSTIGPYPNGMRLEGFPNS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNRWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMVTGW
                     VKDDSTWYYLNAGNGDMKTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(11270..12502)
                     /locus_tag="VW883_001744"
     CDS             complement(11270..12502)
                     /locus_tag="VW883_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0274843.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEISHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(12545..13507)
                     /locus_tag="VW883_001745"
     CDS             complement(12545..13507)
                     /locus_tag="VW883_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0274844.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
BASE COUNT         4204 a         2368 c         3145 g         4102 t
ORIGIN      
        1 aaaatctggg tgataaatgt tatggttgtg ctggttgagg attctgattt tgttgatcag
       61 gggttgtatt tgattgttgc gtattattgt taggattggt agtcgtacta ttatttgtgc
      121 ttggagtggt tgagctagac tgtgaagttg aactatctga tgatgagctt gaactttcag
      181 ttgatggggg ttgttgtgga gcaggtgagt tccacgtaga acgagcacca tttttaaata
      241 cgaattctcc atttctgtag agcccctctg gtatattcca atcttctgga ttgcttcctt
      301 cagacaggta ggtcatcata gagcggtaaa ctttggcagc gaccgtaagg ccattgccta
      361 caagtggtgt cagacggtta gaatagcctg tccatacagc cattgaatat ttacgcgtat
      421 agccagcaaa tagttcatca ggtgctacaa attgagaggt cttgatgtgg ttttcaattt
      481 cctcgtctgt atagttagag gttcctgttt taccagcctg aggaagccaa gcaagatagg
      541 catttcgtcc agttccataa gtcaagactg ttttcatcat gtcggtcatc atataggctg
      601 tcgtttcttt catggcacga gttccgacat tagagaactc tttttcactc ccatcactaa
      661 agacgacttt atggatatac attggtttat agtaagttcc accatttgca aaggcagcgt
      721 aagcagcagc catcttttca ctacttgctc catatttttt gtctgattcg gttgtgttac
      781 ttgaaatggc atttgagtag tgaatacttg ggtagtcgat tccgagacca tttaggaaag
      841 tcttggcgcg gttgagtccg accttgttta gagtttccac ggctgggacg tttcgcgatt
      901 gttgcagggc gtattgcaag gtgatgttgc caaagtagcc cctatcccag ttataaacag
      961 gagtatttgt cccagggtaa ttatagggct catcgtgaac gatagtagca gttgaatcgt
     1021 agacaccgta ctccaaggca ggagcatagt ctgtgatcgg tttcatagtt gatccccagt
     1081 cgcggtttgt ttctactgct tggttaattc cgaaggaaac attacttgac tgatggcgtg
     1141 ctcctagctg ggcaatgact ttaccgttag aaacatcaac aatggtagaa gcgacttgca
     1201 attcatcgtc tggataggca acgtattcgt ctgtattgta aatatcccac agatgttttt
     1261 gagcttcttg gtctacattt gtgtagacat ccatcccagt tgtgagcagg ttatagcctg
     1321 tttcttcttc aacttgattg atgacttcct tgaggtaatt atccatgtaa gcagggtaat
     1381 tacttgctga tttgagactt tgtagtccat cagtaattgg tgtattgact gctttctcat
     1441 actgttcagc agagatgtag ccttgatttt tcatttcaga taagaccaag tttcggcggt
     1501 cttgggctgc ttctggatgt gaataggggt catattggtt tggtgcctga ggcattccag
     1561 ccagcaaggc taactgaggt aaacttaaat tattgaggtc tttaccatag tagttttgag
     1621 ctgctgtctg cattccatag ttcccattag acatgtagac cttatttata tagtaggtca
     1681 agatttcttg cttggttgct ttttgttcta actgaatcgc taaccaagct tcctgagcct
     1741 tacgagaaat agtctggtcg gaagtcgaag ttgaaaagta agtcaactta atcaactgtt
     1801 gggtgagagt tgatccacct tggagggaat tgctttgcag attgcgcaag aaagctccca
     1861 ggatacggat ggtatcaatc cccctgtggt cgaagaagcg atggtcttcg atagaaacga
     1921 ttgccttaac caaatctgtg ggaatatcat tagcttgggc attgacgcgg cgttcagaac
     1981 ccaagtcagc aatgagttga tttttattgt cgtagatttt actagaagtt gttgcaacta
     2041 gtttactctc ggataggcta ggagccttgc taacgtagta gaaaaaaact cctccgccta
     2101 agacaatggc tgcgataacc aagcttaaga agctaatgct cagatacttg attaggcgca
     2161 gaatcgttgg tttgttcatc ttgttttacc acctaataaa tgttctttga taacattgag
     2221 ataaggaatt tgagggaagg caccagcctt gatttcatat ccatattctc gaatatattc
     2281 aagtggcatt gatttttgtc ccttatcttg atgatagaag cgaatcaaat cgaatgccgg
     2341 caataagtag gtttcttgct gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg
     2401 ggcaaggact tgttccatat gctgaatctg atgtggatga aaatttttca tcggaatcgc
     2461 acgtttttgt tttgtttcct tgacttcaaa gtcgatgtaa tatccattat aaacgccaga
     2521 atagtccgtc gttgaagctt gtcgaaaata ggcttcaaca atcttggcac gacttcgttg
     2581 tggatagtcc acttgtacga tttgaatagg agttggtttc ttatgtataa cagccaagcc
     2641 ctgagacaaa tagtagtcgt tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt
     2701 tgcgaaattt ttgggttgag aaagagatgt ttgtcttttt tgtgatgaaa ctttatgtgg
     2761 atagttgacc ataattctcc ttattggtac aataacatca ctttattata ccataatttg
     2821 cacagaaagg gttaaaaatg gctacagctt tggttttagg ctattctgct tttgatttgg
     2881 gtttattttc tgataaggat cctcgtctta aattgattaa aaaagcgata cgtaaagatt
     2941 tagaggctat ggcagcagat ggggtgtctt ggcttgtgtt tacaggaagt ttgggttttg
     3001 aatattgggt tttagaggtt gctcaggaga tgaaaaccga atacggtttc cagttggcca
     3061 ccatttttgc ttttgaaacc catggggaaa attggaatga aggcaatcag atgaaactga
     3121 gtcgctttaa gcaggtagac tttgtcaaat atgcttatcc tcgctatgaa cacaaggggc
     3181 agttaagaga ttaccagcag tttttgctgg aaaacacgac tagttcctat cttttttatg
     3241 atgaagaaaa tgaaacaaaa ctagcttatt tttaccaaaa gatgaaaaat caagaggact
     3301 attttataaa gagattaaca tttgatcaat taaatgaact tgctgaaaat ttttccgaaa
     3361 attgaagctt tgaccttgat ttttgtttgc ctttttttat ataataatac tagcaagcga
     3421 gaatggagag agacatggca agtattattt tttcagcgaa agatattttt gatcaagagt
     3481 ttggacgtga agtccgtggc tataataaag tagaagttga cgagttttta gacgatgtca
     3541 tcaaggacta tgaaacctat gctgccttgg tcaagtcact tcgtcaggaa attgcggatt
     3601 tgaaggaaga attaactcgt aaaccgaaac cttcaccagt tcaagcagaa ccccttgaag
     3661 cggcaattac aagttctatg acgaattttg atattttgaa acgcctgaat agattggaaa
     3721 aagaagtttt tggtaaacaa attttagata actcagattt ttaagtagtt atttgagatg
     3781 tgcaattttt ggataatcgc gtgaggagaa ttgcttctca tgaggaaagt ccatgctagc
     3841 acaggctgtg atgcctgtag tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa
     3901 tcgttacggc agttgaaatg gctaagtcct tggataagcc agagtaggct tgaaagtgcc
     3961 acagtgacgg agtctttctg gaaacagaga gagtggaacg cggtaaaccc ctcaagctag
     4021 caacccaaat tttggtcggg gcatggagta cgcggaaacg aacgtagtat tctgactgct
     4081 atcagttaga gctgttagtg gtagacagat gattatcgaa ggaagtggtc ctagtcactt
     4141 ctggaacaaa acatggctta tagaaaattg catataggtt ggggctgaga aattttctca
     4201 acctcatttt ttaaagtgga catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga
     4261 atttaattta attgcaactg tggcagcagg gcttgaggct gtcgttggtc gtgaagtgcg
     4321 agagttgggc tacgattgtc agattgaaaa tggacgtgtt cgttttcaag gagacgtgag
     4381 agctattatc gaaaccaacc tttggcttcg ggcagcagat cgtatcaaaa ttatcgtagg
     4441 aacgttccct gctaagactt ttgaagagct atttcaggga gttttcgctt tagattggga
     4501 aaattattta ccacttggag ctcggttccc gatttcaaaa gctaaatgtg ttaagtccaa
     4561 acttcacaat gagcccagtg ttcaggctat ttctaagaaa gctgttgtca agaaattgca
     4621 gaaacactat gctcgcccag aaggggttcc tctgatggag aatggcccag agtttaagat
     4681 tgaggtctct attctcaaag atgtggcaac tgtcatgatt gatacgaccg ggtctagcct
     4741 ctttaaacgt ggttatcgta ccgaaaaagg tggcgctcct atcaaggaaa atatggcagc
     4801 agccatttta caactttcta actggtatcc agacaagcct ttgattgatc cgacctgtgg
     4861 ttcggggact ttctgtattg aggcagttat gattgctaga aagatggcgc caggtcttcg
     4921 tcgctctttt gcatttgagg aatggaactg gatcagcgat cgcttgattc aagaagtgcg
     4981 cacagaagcg gctaaaaaag tagaacgtga gcttgagctg gatatcatgg gctgtgatat
     5041 tgatgctcgc atggtggaaa ttgctaaggc caatgctcag gtggctggtg ttgcaggaga
     5101 cattactttt aagcagatgc gcgtgcagga tttacgttcc gataaaatca atggagtaat
     5161 catttccaat ccgccttatg gtgaacgttt gtcagatgat gcaggggtga ccaagctcta
     5221 tgctgagatg gggcaagtat ttgcaccgct gaaaacttgg agcaaattta tcctgactag
     5281 tgatgaagct tttgaaagca agtatggtag ccaagcagat aagaagcgta agttatacaa
     5341 cggaaccttg aaagtggatc tgtatcaata ttttggtcag cgtgtcaaac ggcaagaggt
     5401 aaaatagaaa gggatactca tgagtaaaaa aagacgaaat cgtcaaaaaa aagaaggtca
     5461 agaaccgcaa tttgattttg atgaagcaaa agagctaaca gttggtcaag ctattcgtaa
     5521 aaatgaagaa gtggaagcag gagtcttgcc tgaggattcc attttggaca agtatgttaa
     5581 gcaacacaga gatgaaattg aggcggataa gtttgcgact cgtcaataca aaaaagagga
     5641 gttcgttgaa attcagagtc tggatgattt aattcaagag atgcgtgagg ctgtagagaa
     5701 gtcagaagct tcttcggagg aagttccatc ttctgaagac atcttactac ccttgcctct
     5761 ggacgatgag gagcaaggct tggatcctct attgctagat gatgaaaatc caacagaaat
     5821 gactgaagaa gtggaagagg agcaaaacct ttctcgtctg gatcaagagg actcagaaaa
     5881 gaaaagtaaa aaaggcttta ttttgaccgt tttggcgctt gtatcagtaa ttatttgtgt
     5941 cagtgcttat tatgtctacc gtcaagtggc tcgttcgacc aaggaaattg aaacttctca
     6001 atcaactaca gccaatcaat cggatgtgga tgattttaat acactttatg acgcctttta
     6061 cacagatagc aataaaacgg ctttgaaaaa tagccagttt gataaactga atcaactcaa
     6121 gactttactt gataagctgg aaggtagtcg tgaacatacg cttgccaaat ctaaatatga
     6181 tagtctagca acgcaaatca aggctattca agatgtcaat gctcaatttg agaaaccagc
     6241 tattgtggat ggtgtgttgg atgccaatgc caaagccaaa tcggatgcta aatttacgga
     6301 tattaaaact ggaaatacgg agcttgataa agtgctagat aaggctatca gtcttggtaa
     6361 gagccagcaa acaagtactt ctagctcaag ttcaagtcaa actagcagct caagttcaag
     6421 tcaagcaagc tcaaatacga caagtgagcc aaaaccaagt agttcaaatg agactagaag
     6481 tagtcgcagt gaagtcaata tgggtctctc gagtgcaggg gttgctgttc aaagaagtgc
     6541 cagtcgtgtt gcctataatc agtctgctat tgatgatagt aataactctg cctgggattt
     6601 tgcggatggt gtcttagaac aaattctagc gacttcacgt tcacgtggct atatcactgg
     6661 agaccaatat atccttgaac gtgtcaatat cgttaacggc aatggttatt acaacctcta
     6721 caagccagat ggaacctatc tctttaccct taactgtaag acaggctact ttgtcggaaa
     6781 tggcgctggt catgcggatg acttggacta ctaagcagtc gttacaaaat tctttctttt
     6841 caaaagtaaa aatgataaaa taaaacaaat gaaacaagag gagtgtcaaa tgacaaaagc
     6901 taactttggt gtcgtaggta tggccgtaat gggtcgtaac cttgccctta atattgaatc
     6961 tcgtggttac acagttgcta tctacaaccg tagtaaagaa aaaacggaag atgtgattgc
     7021 ttgccatcct gaaaagaact ttgtaccaag ctatgacgtt gaaagttttg taaactcaat
     7081 cgaaaaacct cgtcgtatca tgctgatggt tcaagctgga cctggtacag atgctactat
     7141 ccaagccctt cttccacacc ttgacaaggg tgatatcttg attgacggag gaaatacttt
     7201 ctacaaagat accatccgtc gtaatgaaga attggcaaac tctggtatca actttatcgg
     7261 tactggggtt tctggtggtg aaaaaggtgc ccttgaaggt ccttctatca tgcctggtgg
     7321 acaaaaagaa gcctacgaat tggttgcgga tgttcttgaa gaaatctcag ctaaagcacc
     7381 agaagatggc aaaccatgtg tgacttacat cggtcctgat ggagctggtc actatgtgaa
     7441 aatggttcac aatggtattg agtacggtga tatgcaattg atcgcagaaa gctatgactt
     7501 gatgcaacac ttgctaggcc tttctgcaga agatatggct gaaatcttta ctgagtggaa
     7561 caagggtgaa ttagacagct acttgattga aatcacagct gatatcttga gccgtaaaga
     7621 cgatgaaggc caagatggac caatcgtaga ctacatcctt gatgctgcag gtaacaaggg
     7681 aactggtaaa tggacgagcc aatcatctct tgaccttggt gtaccattgt cactgattac
     7741 tgagtcagtg tttgcacgct acatttcaac ttacaaagaa gaacgtgtac atgctagcaa
     7801 ggtgcttcca aaaccagcta ccttcaactt tgaaggagac aaggctgaat tgattgaaaa
     7861 aatccgtcaa gccctttact tctcaaaaat catttcatac gcacaaggat ttgctcaatt
     7921 gcgtgtagcc tctaaagaaa acaactggaa cttgccattt gcagatatcg catctatctg
     7981 gcgtgatggc tgtatcatcc gttctcgttt cttgcaaaag attacagatg cttacaaccg
     8041 cgatgcagat cttgccaacc ttcttttgga cgagtacttc ttggatgtta ctgctaagta
     8101 tcaacaagca gtgcgtgata tcgtagctct tgcggttcaa gctggtgtgc cagtgccaac
     8161 tttctcagca gctattactt actttgatag ctaccgttca gctgaccttc cagctaactt
     8221 gatccaagca caacgtgact actttggtgc tcacacttac caacgtaaag acaaagaagg
     8281 aaccttccac tactcttggt atgacgaaaa ataagtaggt cagccatggg gaaacggatt
     8341 ttattacttg agaaagaacg aaatctagct cattttttaa gtttggaact ccagaaagag
     8401 cagtatcggg ttgatctggt agaggagggg caaaaagccc tctccatggc tcttcagaca
     8461 gactatgatt tgatgttatt gaacgttaat ctgggagata tgatggctca ggattttgca
     8521 gaaaaattga gtcgaactaa acctgcctca gtcatcatga ttttagatca ttgggaagac
     8581 ttgcaagaag agctggaagt tgttcagcgt tttgcagttt catacattta taagccagtc
     8641 cttatcgaaa atctggtagc gcgtatttcg gcgatcttcc gaggtcggga cttcattgat
     8701 caacactgca gtctgatgaa agttccaagg acctaccgca atcttaggat agatgttgaa
     8761 catcacacgg tttatcgtgg tgaagagatg attgctctga cccgccgtga gtatgacctt
     8821 ttggcgacac ttatgggaag caagaaagta ttgactcgtg agcaattgtt ggaaagtgtt
     8881 tggaagtatg aaagtgcgac cgagacaaat atcgtagatg tctatatccg ctatctacgg
     8941 agcaagcttg atgttaaagg ccaaaaaagc tacattaaaa ccgtgcgtgg tgttggatat
     9001 accatgcaag aatagataag cagttgcagt tgtgtaactg cttttttgag gagtttttat
     9061 atattgacat gcagtcgggt ctttgctaca atcgttttag gaggatatat agatgaaact
     9121 tttgaaaaaa atgatgcaag ttctactagc agtctttttc tttggtttgc tagctacaaa
     9181 tacggtattt gcgaatacca caggtggccg atttgttgat aaggataata gaaaatatta
     9241 tgtaaaagat gatcataaag caatctattg gcataaaata gacggtaaaa cttactattt
     9301 tggtgatatt ggagagatgg ttgtcggttg gcaatactta gaaattcctg gaacaggtta
     9361 tcgtgataat ttattcgata accaaccagt taatgaaatt ggccttcagg agaagtggta
     9421 ctattttgga caagatggtg ctttgctaga acaaacagat aaacaagtac tagaggcaaa
     9481 aacgtctgaa aatacaggaa aagtatacgg tgaacaatat cctctatctg ctgaaaagag
     9541 aacttattat tttgataata attatgctgt aaagacaggc tggatttatg aagagggtca
     9601 ttggtattat ttaaataagc taggaaattt tggcgatgat tcttacaatc cactaccaat
     9661 tggtgaagtt gctaagggtt ggactcaaga ttttcatgtt actattgaca ttgatagaag
     9721 caaacctgct ccatggtact acctagatgc ttcaggtaag atgcttacag attggcaaaa
     9781 agtaaacgga aaatggtatt attttggctc ctctggttct atggcaacag gttggaaata
     9841 tgtacgaggc aaatggtatt acttagataa taaaaatggc gatatgaaaa caggttggca
     9901 aaaccttggg aacaactggt actacctccg ttcatcagga gctatggtaa ctggctggta
     9961 tcaagatggt tcaacttggt actatttaga tgctgaaaat ggtgatatga aaataggttg
    10021 gacaaaagta aatggaaaat ggtattatct caattcctct ggagcaatgg ttacaggtag
    10081 tcaaactatc gatggtaaag tttataactt cgcttcatct ggtgagtgga tttaatgtta
    10141 gaggatatat aaaatgaagc ttttgaaaaa aactatgcaa gctggactaa cagtaatttt
    10201 ctttggtttg ctagctacga atacagtatt tgcagataac tctgaaggat ggcagtttgt
    10261 ccaagaaaac ggtagaacct attacaaaaa gggggacctc aaagaaacct actggcgagt
    10321 gattgatggt aagtactatt attttgattc tctatctgga gagatggttg tcggctggca
    10381 atatatcccg tttccatcta aagatagtac aattggtcct tacccaaatg gtatgagatt
    10441 agaaggtttt ccaaattcag agtggtacta cttcgataaa aatggagtgc tacaagagtt
    10501 tgttggttgg aaaacattag agattaaaac taaagacagt gttggaagaa agtacgggga
    10561 aaaacgtgaa gattcagaag ataaagaaga gaaacgttat tatacgaact attactttaa
    10621 tcaaaatcat tctttagaga caggttggct ttatgatcag tctaactggt attatctagc
    10681 taagacggaa attaatggag aaaactacct tggtggtgaa agacgtgcgg ggtggataaa
    10741 cgatgattca acttggtact atttagatcc aacaactggt attatgcaaa caggttggca
    10801 atatctaggt aatagatggt actacctccg ttcctcagga gcaatggcca ctggctggta
    10861 tcaggaaggt accacttggt attatttaga ccagccaaat ggcgatatga aaacaggttg
    10921 gcaaaacctt gggaacaaat ggtactatct ccgttcgtca ggcgccatgg tgactggctg
    10981 ggtgaaagat gactcaactt ggtattacct aaatgcaggt aatggagaca tgaagacagg
    11041 ttggttccag gtcaatggca gatggtacta cgcttatagc tcaggtgctt tggcagtgaa
    11101 tacgaccgta gatggctatt ctgtcaacta taatggcgaa tgggttcggt aatgacaggg
    11161 cgcttataat tatattagaa cactcgctta atcaaagaag tgactttgtt gtacttgacc
    11221 tgacgattgg ggagattaaa agcatgtgaa atctacacat gctttttcgt tagttatgag
    11281 tgttgaactt gactaaccat tgacaaaaga taagagcaat taaaataaga tacaaaaata
    11341 tcaatgctaa ctgcaccgaa acgcccgatg ctatggatag ggctaatagg gagagcaggg
    11401 acggggcgag aatgtccact gtgctcagag cagagcccac cgtccccatc ttgtcactgg
    11461 ggatatgggc aaagacagct gcttgtaggc gagggctgag aatgccgata atcgtagaac
    11521 tgatgaaact ggtcatgaaa attacgatat aggcttgaca aaggatacta gttattagag
    11581 tcaataggga aatctcacag aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat
    11641 tactgctggt catattgcca aggatagctc cacaagacat gatgatggag agcagggcga
    11701 ggagttgccc aatgctcagt tgtgctagtg tctgttggat gaagcggagg gcaatcagcc
    11761 gaggggacac atccaagatg gcaatcatac tggtcgtcag aaacagtagt atgacggtat
    11821 cttttaacct caggagcaca gccagcgact gtttaagatg ttgaaaatat ttcttaaaac
    11881 tcagtgctgt atgtgatatt tcaattcttt tttcaacctc atacaaggta tgtcgaataa
    11941 catacaggcc caaaaaggca atgacaaaag tcagagtgtt gataagggaa atagtttgaa
    12001 tacttataac attgataagg aatgcgccag ccagattggc gacaatacgg acaaccctca
    12061 tcagagactg cctgaacccc atggcatcat gcaggtcgtc cttaattaca ctgatgtaga
    12121 gggcgttcat catgtaggca gacaggtagc tcaaggtgtc agagatgagg ttgatgatga
    12181 caatcataat gactgaaact aatgaaaagg gcgacaagac gagaaatact gtcaaaatag
    12241 cgtagagcag gattttgatt ttggcaatcc agagtgcgtg tttgactcta ttttcttgaa
    12301 aatctcctag aatcccgaga aagagttgcg atagtagggg aaccatctct gaaatggaaa
    12361 tcagtaaaat cgctagcgga gcgaaattgt actgagccac ataattgata atggcgaggt
    12421 agaaaatact gtcgccgaat gatgaaaaac agctgtttag cagcaactgt ctatatatgt
    12481 tgtttgtcca aaataatttc atacttttct ccttatgtct gcacatcgaa tgggaattta
    12541 ttatttaata gacaccaata taccccatgc ttcctattcc gaagtcaaac aaatctgctt
    12601 taccactatc tccttgaaac atcagtaaac cgtgatcatc tcgttcagaa catgctaaaa
    12661 ttacctgttg gatttttttc atcagtaatt tgttttgatt gtagacagtg gtttgtagta
    12721 agctagttat tccgtggcaa tatcctgtca tcatttttag atgatggtta aaaacaaatt
    12781 cttgatattt actaataata tctttgtttc cgtcacaatc gtacatacaa agatataaga
    12841 ttattccgga aattcctttg caccaagaaa gttgtaaatt tcctaaattt tcagtattag
    12901 aagtaacttt ttctaataat ttttttaatt cagtatggaa tgtatggaga tcattataga
    12961 acatagaagg ttctaagact ttagaatagg caaataaagc atatgcaatt ccacaatatc
    13021 catgagcaaa gctatagtct aaaatgcttt ctttggctgt atctctttgt aggaaataat
    13081 gataaatttc ccctatacta ttgtggatga aaattttaag agtattgtca ttggtaaatt
    13141 gatagtattt tattaatgat aataggacac cagattttcc caatgcaaag tctatttcct
    13201 ctaaagtatc ataattctct attaattttt tagcggtgac gtttgctaat tgtagatagt
    13261 attgattttt actgatagaa aataaatgta ggagtaacca tagatagcct gcatcaccaa
    13321 atagcagtga gtattgatat tcatatgtat gtgtcgttct aattgtcact gccttcttga
    13381 tgatagagag tattttagaa tccagttctg gggggtacaa tttatttaga ggaaacagta
    13441 gtccagctat tccgtgttgg aatgataaat tacttacgaa atttccaaat tctgttgaag
    13501 aagtgatcct tccttcagaa tttacagttt tatctagtaa aaattgtaga acactattac
    13561 attctgtttt gtaatcatat ttatgttcct ctattttttt aattttgact aaattatttg
    13621 tttgacttaa atttagtaga cattgtaacc aaaatagttg ctcatctgtg agctgacctt
    13681 gagtatgtga tagttctagt aattgaatag gatcctttag ttagattcaa tcaatctata
    13741 acacaacaac ataataatac ttttaggata gcttgtcaaa tattatagta aaatgagata
    13801 ataacaggat aaatcgatc
//
LOCUS       DAVKXA010000052        12507 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKXA010000052 DAVKXA010000000
VERSION     DAVKXA010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.052"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(187..624)
                     /locus_tag="VW883_001746"
     CDS             complement(187..624)
                     /locus_tag="VW883_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0274845.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(709..3342)
                     /gene="polA"
                     /locus_tag="VW883_001747"
     CDS             complement(709..3342)
                     /gene="polA"
                     /locus_tag="VW883_001747"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0274846.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELMDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3593..3943
                     /locus_tag="VW883_001748"
     CDS             3593..3943
                     /locus_tag="VW883_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0274847.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4158..4274
                     /locus_tag="VW883_001749"
                     /pseudo
     CDS             4158..4274
                     /locus_tag="VW883_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            4267..4500
                     /locus_tag="VW883_001750"
     CDS             4267..4500
                     /locus_tag="VW883_001750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274848.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            4627..4905
                     /locus_tag="VW883_001751"
                     /pseudo
     CDS             4627..4905
                     /locus_tag="VW883_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5042..6010)
                     /locus_tag="VW883_001752"
     CDS             complement(5042..6010)
                     /locus_tag="VW883_001752"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0274849.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(6155..6778)
                     /locus_tag="VW883_001753"
     CDS             complement(6155..6778)
                     /locus_tag="VW883_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV0274850.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIKDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIAFYGFYHAYCFVEKHNELMT"
     gene            complement(6760..6969)
                     /locus_tag="VW883_001754"
     CDS             complement(6760..6969)
                     /locus_tag="VW883_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274851.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            complement(6994..7491)
                     /locus_tag="VW883_001755"
     CDS             complement(6994..7491)
                     /locus_tag="VW883_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0274852.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7564..8925)
                     /gene="radA"
                     /locus_tag="VW883_001756"
     CDS             complement(7564..8925)
                     /gene="radA"
                     /locus_tag="VW883_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0274853.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8939..9454)
                     /locus_tag="VW883_001757"
     CDS             complement(8939..9454)
                     /locus_tag="VW883_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0274854.1"
                     /translation="MKIIFVRHGEPDYSELEERSYIGFGINLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9456..9899)
                     /locus_tag="VW883_001758"
     CDS             complement(9456..9899)
                     /locus_tag="VW883_001758"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0274855.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(9956..10053)
                     /gene="ffs"
                     /locus_tag="VW883_001759"
     ncRNA           complement(9956..10053)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VW883_001759"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(10086..10553)
                     /locus_tag="VW883_001760"
     CDS             complement(10086..10553)
                     /locus_tag="VW883_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0274856.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(10754..12040)
                     /locus_tag="VW883_001761"
     CDS             complement(10754..12040)
                     /locus_tag="VW883_001761"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0274857.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(12271..12507)
                     /locus_tag="VW883_001762"
     CDS             complement(12271..12507)
                     /locus_tag="VW883_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0274858.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         3910 a         3038 c         2132 g         3427 t
ORIGIN      
        1 caacctcaaa acggtgtttt gagctgactt cgtcagttct atctacaacc tcaaaacggt
       61 gttttgagct gacttcgtca gttctatcta caacctcaaa acggtgtttt gagcagcccg
      121 cggctagttt gctctttgat tttcattgag tataacacaa aaggtagccc atcagctacc
      181 tttttcttat gcttcctcaa tcaagcgagt atgttctctc ttgatacagc gattcatcac
      241 gatatcatca catccaccat cacgcaaaat ctctttcgct tctaaacttt caagtcctag
      301 ctgtgcccaa aaaatcttgg catcagcttt gagaaaatca cgcgccacat cgggcagaaa
      361 ttcactgcga cgataaacat tgacaatatc tacaggaaaa ggaatttcag cgaggctagc
      421 ataagccttt tcacccaaga tttcgccacc tgccgccttg ggattgactg ggatgatttt
      481 atagccccga gcctgcattt cctttgttac tcgattgctg gttgtttctt cacggtcaga
      541 caaacccacc acagcaaggg ttttactcgt tgcgagatac tgacgaatca cgccatcact
      601 tggattgata aattcttgac tcatagaaat cctccttttt catcagtata gcacattttg
      661 aaaaggtttg cagaattcta ctacaaaaaa ggaggactag cccccttttt atttagcctc
      721 gtaccaggtt gccccttcat tctcatctgc gataagagga acactgagtt gaatggcttc
      781 ttccatggtt tgtttcacca atttttttat ctctaccaat tcagatttag gcacttcaag
      841 gacgatttca tcgtgcactt gtaacagcat cttagtctga taaccacctg caaccaaggc
      901 tttatccagc tgaatcatgg caatcttgag aatatctgct gccgaaccct ggataggtga
      961 gttgatagca gttcgctccg caaaaccacg aatattgaag ttgcgcgaat tgatatctgg
     1021 caactcacgg cgacgcttaa agagggtctc tacatagccc ttatcacgcg cctcccgcac
     1081 cacttcatcc atgtagtttt taatacctgg aaaacgttca aagtaggtat caatgtaggc
     1141 tttggcttcc ttacgactaa ttcccaaatt attagacaag ccaaagtctg aaatcccata
     1201 aaccactcca aagttaactg ccttggcatt gcgacggtca tttgcagtca cattatcagg
     1261 acgctcaatg ccaaagaccc gcatggctgt cgaagtatgg atatctgccc cctcttggaa
     1321 ggccttaatc aagtgctcat ccttagaaat atgcgccaaa acgcgcaatt caatctgtga
     1381 ataatcagag ctgagtagca cactatcctc ccactctggc acaaaagcct tccgaatcaa
     1441 gcgcccttgt tccaatcggg caggaatatt ttgcaagttt ggatccacac tagacaaacg
     1501 cccggtctgg gtcaaatcct gcacatagcg agtatgaatc tttccatcag ccaaaatcca
     1561 gtcctgcaag ccaattacat aagtagattg aatcttagca atttgacggt aatccaggat
     1621 tttcttaaca atcggagcaa taggagcgag acgctccaaa acatccactg ctgtcgaata
     1681 acctgtcttg gttttcttag tgtattctag aggaagtccc aatttctcaa agagaagcac
     1741 gcccaactgc ttaggcgagt tgacattaaa ctcctcaccg gccagctcgt aaatctcttg
     1801 agtcagtttt tcaatgacaa gctcattttc agcctgcatc tcaagcaagg tctctttctt
     1861 gaccataatc ccagcaattt ccatcttggc aaggacaaaa gccagaggtt gctccatatc
     1921 ataaagaagc tctaattgcc cattttcgct gagtttttca agtaaaatag gctctgtttc
     1981 taccaaaaca gcaagtttac aagctaagtg ttccaagaat ttctcacgtt caggaatggc
     2041 ctttttaaca cccttaccgt agaaagtttc atcatcaacc aagtaagtct gaccataaag
     2101 actagcgatg gtcgcaattt cattgtcctc cacagtcgaa aggaggtatt tagccaaacg
     2161 gatgtcaaaa gcaggcgcct gcaaatccac accaaaacgt tgcaaaagaa ctttaacctt
     2221 cttaaagtca taaactctca gagatgtttt ttctaagaaa tccttgaaaa tcgggtcttg
     2281 caacagttca agcttgtctg tggcatagag cttatcccca caagaccagg caaatccaac
     2341 caaattatcc gtatggtaat tctcaccaaa aagctcaaag tggaagatag actcttcact
     2401 cagcatatct tgactgattt ggtcaacaat agtaaaatcc aaactctcag acacatcagc
     2461 tgacgacaca tttaaagcct gcttgagctg tttgaagccc atctcatcgt agaatttccc
     2521 aagattttca acatctggac cactatagac caagtcctct aaaccaatcg caatcggtgc
     2581 cttggtatca atggtcgcta gtgttttaga caaaaaggcc tgttccttgt cattgatgag
     2641 attttccttc atcttagaag tcttcattcc atcaatattt tcataaatcc cctcaagcga
     2701 accatgctcc agcaagagct taatacccgt cttttcaccg actttggtca ccccagggat
     2761 attatccgac ttatcaccca tgagcgcctt gagatcgata aactgagctg gtgtgaggcc
     2821 catttcttcc atgaggtaat ctggcgtaaa ggcctcaaac tcagccacac ctttcttgga
     2881 aatttcaacc accgtatgct catccgtcag ctgaatcaaa tccttgtccc cactgacaat
     2941 ggtaatatca aaaccatcct gctctgctag cttatccagc gtcccaatga tgtcatccgc
     3001 ctcatactga gccagctcat agtgacgaat ccccatatga tccatcaact cacgaatgaa
     3061 aggaaattgc tcacgaaact catcaggagt cttggcccga ccacccttat agtccgcata
     3121 catctctgtc cggaaggtcg tctttcccgc atcaaaagcc accaaaatat gactcggctc
     3181 aacccgctcc aacaaatgac tcaacatcaa ctgaaaacca taaatcgcat tggtatgcaa
     3241 accagccgca ttcttaaaac ggtccaactg ctgatacagc gcaaaaaacg cccgaaaagc
     3301 tacagaagac ccatcaatca ataataattt tttcttatcc atacacccat tataaaggaa
     3361 agaatcaaaa aataccattg ggaagagcta gagcaagtat ttttcaaact ttttccgaat
     3421 aaatagatag agccagagaa tttagtaaac ctagatttaa aaatgtgcta taatatattg
     3481 aatctataat agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg
     3541 atagagttat tcacatctta tttcaactca ctatagaagg aggaatagga ggattctcag
     3601 acatccgggc atcagcccaa ctaatgattt gattgctaag aaaatattca gcaatccaga
     3661 aatcacttgt caatttattc gcgatatgct ggacttgcca gcaaaaaatg tgaccatttt
     3721 ggagggaagc gatattcacg tattactctc catgccttac tcagcgcagg atttttatac
     3781 cagtatagac gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt
     3841 ccatcatcag aattttttca tcaatcactt gtggacttac ctgtgcagtc aggttaatca
     3901 aaatcttgaa aaaattcgtc agcgagaagg tgatactcac tagagctaca aacacatcgc
     3961 tcctgtttac gccattgcta tcgtggatag taattatttc tcagatgacc tggcttttca
     4021 tagctttagt atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca
     4081 ggaaaaccat ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaag
     4141 gacgaggttc gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg
     4201 caacgagcca ttagccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac
     4261 aggaaaatgt ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat
     4321 gccttggaaa ctgctagggc tgaaggtctt gaacaaggac tagagcgtgg gaaagttgaa
     4381 ggaagggcag aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact
     4441 tctgaggttg ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa
     4501 aatggctcca taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttg
     4561 tgtagaaaaa aagtcccata tgacctataa tgaaaagcga caaaacaact cattagaaag
     4621 aatcatatgg aacaattaca ttttatcaca aaattactag acattaaaga ccctaatgtc
     4681 cagattttaa acatcatcaa taaggataca cacaaggaaa tcatcgccaa actggactac
     4741 gacgccccat cttgccctga gtgcggaaac caattgaaga aatatgactt tcaaaaacct
     4801 tctaaaattc cttatcttga aacgactggt atgcctacta gaattctcct tagaaagcgt
     4861 cgattcaagt gctatcactg ttcaaaaatg atggtcgctg aaacttatga tgacgtacag
     4921 tcatatttct tctcttttta ttatatcaca gttttaaatc tagctttact agattcaccg
     4981 ctactatcta tttattcgga aaaaagacga aaaaacctga gaatcatctc aggcttggtc
     5041 attaaatttt tttctcaata tcgaaaagtg gagaaagtgg tcgtttttca tgaatacgta
     5101 cgatagcatc ccctaggaga tgagcgattg aaatctgctc aatcttatca atcaaacgct
     5161 cttctggcag atagatggta tccaaaacaa ccaatttctt aatagctgat ttttggatat
     5221 tgtccgtagc aggaccagaa agaactgggt gcgtacagct tgcatagact tcaacagcac
     5281 cagcttccgc aagagcatct gccgcatgac aaatcgttcc agcggtatca atcatatcat
     5341 caatcaagat acaagtcttg ccttcaacct taccgatgat gttcataact tcactagtat
     5401 tcatcttatc aacgctacga cgtttatcaa taatagcgat agatgttttc aaaaattctg
     5461 ccaacttacg agcacgagtc acccctccat ggtccgggct gacaaccaca tagtcagaac
     5521 caaccatacc acgacgctca aaataatctg caatcagagg agcacccatc aaatgatcca
     5581 caggaatatc aaagaatcct tgaatttgcg cagcatgcaa gtcgatggtc aataaacgat
     5641 ccactccagc tacttcaagc atatttgcga caagttttga agtgattggc tcacgcgctc
     5701 tcgcctttct atcctgacgt gcatacccat agtaaggcat gacaacattg acagattctg
     5761 cactcgcacg cttcaaagca tctaccataa tcaaaatttc aagcagattg tcatttacag
     5821 gcgaactagt tgattgtagg ataaagacgt gtttcccacg gattgattct tcaatgttga
     5881 cctgaatctc tccatctgaa aattggcgaa cacttgattt ccccaactct atcccaatct
     5941 cctgcgccac acgttctgcc aattctttat tagaagaaag ggcaaacagc tttaaatcag
     6001 aaaaagacat gatttcctcc ggtatatatg tataacttgt gcttttcaca agattttcca
     6061 tctaccattg tagcgctttt tgcactattt ttcaatcaaa aataaaagaa ggacaccata
     6121 tttgtaccct tgcatcattc ttttgaaaaa tattctaggt catcaactca ttgtgtttct
     6181 caacaaagca ataagcatga taaaaaccat agaaagcaat agccgtaacc actggaatcg
     6241 ctaaaggcaa ctctgtttcc aactccacaa aaggagagtt aaacaagaag tgagttccca
     6301 aggctaaacc tagaaaaata aggccctgtt tcttgccaac cttctgtcct ttataggctc
     6361 tgtaaagcaa gtaaacacct actacagcta gacctgaaaa agtccagtga gaggcaattc
     6421 ctgagatgat acgctctaaa attcgcgaaa tagtaaaatc aaagccctct ggcaaatccg
     6481 tacgaatata accaatatcc ttaatcattt ggaatcccaa accggaagca attccaagta
     6541 aaaacaaaga ttttaatttt cgcacaggaa tcaaagccaa aacaaaaaca agtggcaata
     6601 atttcaaggg ttcttctacc aaaggagcca caatagcact ttcaaaggca tttaaaaatg
     6661 tactatctgg gaaaagaacc cccagtaaat catggatata agtattagca aaactagaca
     6721 accagcctga aaggaacatc cctcccaata aagacagaat caaaaccttc tttggcaatt
     6781 cccatttttc ccaatacgga agagaaaata aagagccgga atcatgtaaa agagagctag
     6841 aaagatagaa actcccatta gtccatattc cgcacctgac ctcgaaccgt ccgtatagta
     6901 gatggtttca tactgtaaac caatacatag caataaaata aaaataaata aaatactgct
     6961 tttcttcata cactttcttt ctaaatgaag tatttataat tctacgactg tcatacttcc
     7021 tgtatcaaca ttgtaaatgg caccagagat aatgacatcg tctggtatta ggggagactc
     7081 gataagcagt tgcatatcct cgcgtacact ctcttctata tcttggaagg gcaagaagtc
     7141 ctggtctgac acatctacac ctaattcctc ttttaaatac tcctgaaaag gttcattttc
     7201 aaaggtctga gcaccacagt ctgtatggtg caataccaca atctctcttg tccccatttg
     7261 ttgctgggaa ataactagcg aacgaatcat gtcttcagtc actcgaccac ctgcattccg
     7321 caagatatga gcatccccaa gtgccaaacc tagagcttgc gcaacgtgca aacgtgagtc
     7381 catacaggtc acaatggcta ctctggtttt aggtttaagt ggcagattta actgcccatg
     7441 tagggcaaca taagcctgat tggcttgcat aaactgttca aaatacgaca cgattccctc
     7501 cttgaaaatt tgatagtcaa atatttctcc tatcttatca tttttaagag aatttgtcac
     7561 ggattatgca aagacctttt tcaagacttc ctgaatcgtt gtcacgccaa tgacctgaat
     7621 ttccttaggc agagtgattc ctgtcaagga attcttaggt acataaatct tagtaaagcc
     7681 cagtttagca gcttcgttga tgcgttgctc aatacgattc acgcgccgaa tctctcctgt
     7741 caagcccagt tctccgacaa aacattcctg aggattagtt ggcttgtctt tgtagctcga
     7801 agcaatagca actgcaacag ccaagtcaat ggcaggttca tccaatttaa caccaccagc
     7861 agatttgaga taggcatcct gattttgcaa gagaagccct gcccgttttt ccaaaacagc
     7921 cataatcaag ctagcacggt taaaatcaag tcctgtcgta gtacgcttgg catttccaaa
     7981 catggtcggt gttaccaaag cctgaacctc cgccaaaatc ggacgcgtcc cttccatggt
     8041 tacaacgatg gaggaaccag tcgccccatc caaacgctct tctaggaaaa cttgactcgg
     8101 attgagtacc tcaaccaagc cgcccgactg catctcaaaa atcccaatct cattagtgga
     8161 accaaaacga tttttgaccg ctctcaaaat acgaaaggtg tggtgacgct ccccttcaaa
     8221 gtaaagcacc gtatccacca tatgctccaa catacgaggc ccagccaagg ttccttcttt
     8281 ggtcacatga cctacgataa agatggcaat gttattggtc ttggccaact gcatgagttc
     8341 agcggtcact tcacgtacct gagaaacaga cccctgcacc cctgaaatct caggagacat
     8401 gatggtctgg atggaatcaa taatgagaaa gtctggctgg atacgctcca cttctgcacg
     8461 aacactctgc atattggtct ctgcatagag ataaaactca ctatcaatat cacctaagcg
     8521 ctctgcacgt agtttaatct gctgggcaga ctcctcccca ctgacataga gaactgtccc
     8581 cacttgggac aactgggttg agacttgtag gagaagagtt gatttcccaa tcccaggatc
     8641 cccaccgatg aggacgagac ttcctggtac cactccgcct ccaagcacac ggttgaattc
     8701 ctccatctcc gtcttggttc gattgacatt gatggaagtc acctcagcta gtttcatggg
     8761 cttggttttc tcacctgtca aggacacacg cgcattcttg acctcggcaa cctcaacctc
     8821 ttccacaaaa gaagaccaag acccacagtt ggggcaacgt cccagatatt taggggaatt
     8881 atacccacaa ttttgacata caaatgtcgc ttttttcttt gcgatgacaa acctctttct
     8941 atatctctaa ctcacactca atcacttggc aaaaatcaat cttctcattt ggcacaaact
     9001 ggcgcatgag cattcgatga gcaacaacta ccacagtctg atgttctcga tacttagaca
     9061 tacattctag aaaccgagac ttcatttccg tagctgtctc atattgaata ggactattag
     9121 gaagcaactc ccccttgttt tctaaaaaca gtcttctagc tgtttcaaag ttttctattc
     9181 ctgttttata gacctgccat tcatgtaata aaggctctac tcttaaagga agacccgtag
     9241 cacagaccac atacgaagcc gtttctaaag ctcttgtgac tgcagaagat acgattattt
     9301 cagctgacga gagtaaagga tttttgctca atttctggac ttgctgccgt cccatctcag
     9361 acaagggtgc caaatttatc ccaaatccta tataagaacg ctcctctaac tcactgtaat
     9421 ccggctcccc atgacgtaca aagataatct tcattctagt gccctgtcga tccaaatcca
     9481 ccagttcgaa cgccatcagc tgcatctcca tctgcaatta agaaagtagc aaaaacagcc
     9541 tggacaatac gctccccaac ttcaagaaca acctcttggt ctgtgatatt cttcatctgc
     9601 gcaaaaatat gcccttcatt tccaggattt ccataataat ccccatcaat gaccccaact
     9661 gagttaatta aaaccaagcc cttcttacga ggatttgaag aacgatcata gaggtagaga
     9721 acctcagtcg gctgcatata agccttaacc cctgtcggaa ccaagacaat ctctcctggc
     9781 gcaacaactg tacgcacagc aacctttaag tcgtaaccag ccgcatgcgc tgtctcacgc
     9841 ttgggcaata aattttcatc tgtaaaactc gaaaccaatt caaaaccacg aattttcata
     9901 attttctctt ttctattatc atttattcta gattattcta tcttatttat tcggaaaaag
     9961 cacgaaaaaa agagcacaca attcaaatcg cttagggctg ctggattcct cccctgaccc
    10021 gcttcacgca gaactgttgc tccactattt attatatcac attcctattc attttaaaag
    10081 caaaattatt ttttccgtct atttctaaaa aaatcctgca tgatagctgc gcattcatct
    10141 tccaaaattc ctatttcaac ctccacacga tgattgagac gctcatctgt caagatatcg
    10201 tacaaactcc cagcagcgcc aaatttctgg tttttagccc catagaccac atttggaatg
    10261 cgggcaagcc caatcgcccc actacacatg acacaaggtt caatggtcac aaaaagtgtg
    10321 caatccagca agcgccagct ctcctcactc aagttcgcat cctctatagc cataatttcc
    10381 gcatgcataa ccgctcgctg taattcctca cgcgcattat gcccacgacc aatgatttcc
    10441 ccatctttga caatcacaca accaattgga atttcatcgt gttcaagagc aatctcagcc
    10501 tctctcaaag cctccctcat aaagacttct ttttcttcaa gcgtataata catctctttt
    10561 ctcttttcct acttatcgat tttattatta tatcatgaat cccaacacaa aaaaagccac
    10621 cgaatgcggt gactctatag ggagattatt atgaaaaaga aaagtttagg atatttgtta
    10681 caacaagtta ggaggtcttc ttgtaactgt ctatagtata cccgacctat cttaaacaaa
    10741 tcttaaaaat ctcttaggac caaacacttt ctaaaatatt tgtttgttca cgaccaggac
    10801 ctactgagaa agtagaaata cgaacgccaa ccaattcact cacacgacga acatagttac
    10861 gcgcattctc aggaagatct tccaaattgc gaactccggt aatatcttct gaccaacctg
    10921 gcaactcttc atagataggc ttgcaacgtt tcaattgctc aagactagct ggatagtagt
    10981 caatacgttg accgtcaaga tcataggcca cacagatttt cacagtatcc aaaccgctca
    11041 aaacatcaat agagttcaaa gaaaggttag taataccaga aacacgacgg ctatgacgca
    11101 tcacaactga gtcaaaccaa cctacacgac gtggacgacc agttgttgta ccatactcat
    11161 gacccacttc acggatacgt tctcccactt catcaaacaa ctcagttggg aaaggaccat
    11221 ctcctacacg actcgtataa gctttacata cacctacaac cttgtcaatc ttgcttggac
    11281 cgacaccaga accaattgtc acaccaccag ctacagggtt tgatgacgta acaaatggat
    11341 aagtaccttg gtcgatatct agcataacac cttgtgcacc ttcaaaaagc acacgtttgc
    11401 cattatcaag cgcatcattc aagataacag atgtatctat cacgtatttc ttgatttgtt
    11461 gaccatattc gtaatattct tcaaaaatat catcgaaaac aatcgcttta ctgtcataca
    11521 atttttcaaa aagacgattc ttttcagcaa ggttacgttc taaacgctca cggaaaatat
    11581 ctttatctaa aagatctgca atacgaattc caacacgagc agccttgtcc atataagctg
    11641 gaccaattcc cttaattgtc gtaccaatct tattgtcgcc cttagcttct tcttgcaagc
    11701 gatccaactc gatatgataa ggcaaaataa catgcgcacg atcagaaata cgcaagttat
    11761 cagttgttac accttcctca tgaagatagc tcaactcttt tacaagagat ttaggattta
    11821 caaccatacc attcccaatg acagatattt tttcagggaa gaaaatccca gatggaatca
    11881 agtgcaactt aaatttctta ccgtcaatca caatcgtgtg accagcatta tcaccacctt
    11941 ggtaacgtgc aatcacttct gcattcgctg aaaggaagtc tgtaatcttc cctttacctt
    12001 catcacccca ttgggtacct acaacaacaa ctgaagtcat aattttgtct gagccctcag
    12061 gctcttcctt tctcacatac atggcaggac tctcacctgc aattatatct tacaatttat
    12121 tataataaaa aatcgccttt ttatcaagaa gaaacaatag aaagatttgc tatttccaac
    12181 tattaaaaaa tgatttagaa aaattactag ctatttacta ttatctttac ataaaagagt
    12241 aaattagttc ggaaatttac taaaattacc tcaacaagaa ataaaacccc gattcattac
    12301 caatttttca agatacaaac gataagcaac acgataatgg taaacgataa aatccctatg
    12361 acaaccaatg ccatatctca ctaaataata aattaaaaat ttaaaatgaa catgttccca
    12421 gtcaaaatta tcaccaaatg taggaccata ctcttcttca atactatcat agaaattagc
    12481 catctgctca taaatttttt gtaacat
//
LOCUS       DAVKXA010000053        12272 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKXA010000053 DAVKXA010000000
VERSION     DAVKXA010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.053"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            111..3212
                     /locus_tag="VW883_001763"
     CDS             111..3212
                     /locus_tag="VW883_001763"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0274859.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGVK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSLHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3295..4302
                     /gene="pfkA"
                     /locus_tag="VW883_001764"
     CDS             3295..4302
                     /gene="pfkA"
                     /locus_tag="VW883_001764"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0274860.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4361..5866
                     /gene="pyk"
                     /locus_tag="VW883_001765"
     CDS             4361..5866
                     /gene="pyk"
                     /locus_tag="VW883_001765"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0274861.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6130..6378)
                     /locus_tag="VW883_001766"
     CDS             complement(6130..6378)
                     /locus_tag="VW883_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0274862.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(6545..6770)
                     /locus_tag="VW883_001767"
                     /pseudo
     CDS             complement(6545..6770)
                     /locus_tag="VW883_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7618..8490
                     /locus_tag="VW883_001768"
     CDS             7618..8490
                     /locus_tag="VW883_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0274863.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8636..8980)
                     /locus_tag="VW883_001769"
                     /pseudo
     CDS             complement(8636..8980)
                     /locus_tag="VW883_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9123..9413
                     /locus_tag="VW883_001770"
     CDS             9123..9413
                     /locus_tag="VW883_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274864.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            9437..10153
                     /locus_tag="VW883_001771"
     CDS             9437..10153
                     /locus_tag="VW883_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0274865.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10283..11098)
                     /locus_tag="VW883_001772"
     CDS             complement(10283..11098)
                     /locus_tag="VW883_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0274866.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11095..12000)
                     /locus_tag="VW883_001773"
     CDS             complement(11095..12000)
                     /locus_tag="VW883_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0274867.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         3833 a         2133 c         2615 g         3691 t
ORIGIN      
        1 tacaaatgaa tagaaaataa attagtaagc tgatgaaatt tttctcaaga gaagctattt
       61 ataggtgaaa atggtataat atagtgagaa ggatagagga gaagtgtaaa ttgatcgcac
      121 aactagatac aaaaacagtc tatagtttta tggaaagcgt catttcgatc gaaaagtatg
      181 tgagagcagc taaagaatac ggctacactc atttggctat gatggatatt gacaatcttt
      241 atggcgcttt cgactttcta gagattacaa aaaaatacgg cattcatcct ttgctagggc
      301 ttgaaatgac agtgtttgta gatgatcagg aagtgaattt gcgcttttta gctctatcta
      361 gtgtgggcta tcagcagttg atgaagcttt cgacagccaa gatgcagggg gtgaaaactt
      421 ggtcagtcct gtcccagtac ctggaggata tcgcggtcat tgtgccttat tttgatagag
      481 ttgagtcgtt agaactaggc tgtgattact atataggggt ttatccagaa acactagcaa
      541 gcgaatttca tcatcctatc ttacctcttt atcgggtcaa cgcttttgaa agcagggata
      601 gagaagttct tcaagtttta acagcgatta aagaaaatct accgctcaga gaagttccct
      661 tgcgttcgag acaagatgtc tttatatcag caagttcttt agagaaacta ttccaagagt
      721 gttttccgca agctttggac aatttagaaa agcttatttc aggcatttct tacgacttgg
      781 atactagtct gaaactgcct cgttttaatc cagctagacc agcagtagag gagttgagag
      841 agcgtgctga actggggctt gttcagaagg ggttgactag taaagaatat caagatagac
      901 tagaccaaga attgtctgtt attcatgata tgggctttga tgattatttc ttggttgttt
      961 gggatttgtt gcgttttgga cgatcgaatg gctattatat gggaatggga aggggttctg
     1021 cagtaggcag tttggtttct tatgccttag acatcacggg gattgaccca gtagagaaaa
     1081 atctgatttt tgaacgcttt cttaatcgtg aacgctatac catgcctgat attgatattg
     1141 atatcccaga tatttatcgt ccagatttta tcagatatgt tggtaataaa tatggtagta
     1201 aacatgcggc acaaatcgtt actttttcaa cctttggagc caagcaagct cttcgagatg
     1261 ttttgaaacg ctttggtgtg ccagagtatg aattatctgc aattactaag aaaatcagtt
     1321 ttcgtgacaa tcttaagtcg gcctatgagg gcaatctcca gtttcgtcag caaatcaata
     1381 gtaagttaga ataccaaaaa gcttttgaga ttgcttgcaa gatagagggc tatccaaggc
     1441 aaacctctgt ccatgcggct ggtgttgtaa ttagtgacca agatttaacc aactacattc
     1501 ctctaaagta tggtgatgaa attccactga ctcagtatga tgctcatgga gttgaggcta
     1561 gcggactttt gaagatggac tttctgggac tacgaaattt gacctttgtc cagaagatgc
     1621 aagagttgct tgctgaaaca gaaggtattc atctgaaaat tgaagaaatc gatttagaag
     1681 acaaagaaac gttagcttta tttgcctctg gtaatacaaa aggtatcttt caatttgagc
     1741 aaccaggtgc cattcgtctg cttaagcgtg tgcaaccagt ctgttttgaa gatgtcgtcg
     1801 cgactacttc tctaaatcga ccgggtgcta gtgactatat caataatttt gtggcaagaa
     1861 agcatgggca ggaagaagtg actgttctgg atccagtact ggaggatatt ttggctccaa
     1921 cctacggcat aatgctctat caggagcagg ttatgcaggt tgcccagcga tttgccggat
     1981 ttagtcttgg gaaagccgat attttgcgtc gggctatggg gaaaaaggat gcctctgcca
     2041 tgcatgagat gagggcttcc tttattcaag gttcattaga agctggtcat actgtggaaa
     2101 aagcagagca ggtctttgat gttatggaga agtttgcagg ctatggtttt aacaggtcac
     2161 acgcctatgc ctactcagca ttggccttcc agttggctta ttttaaaaca cattatccag
     2221 ccatatttta tcagattatg ttgaattctg ccaacagtga ttacttaata gatgcacttg
     2281 aagcaggttt tgaagtggcg cctctgtcca tcaacacgat tccctatcac gataaaattg
     2341 ccaacaaggc catctatcta ggtttgaaat ccattaaagg agtcagtaat gatttagctc
     2401 tctggattat tgaaaataga ccttattcta acattgaaga ttttatagct aaattacctg
     2461 agaattatct gaaacttcct ctgctagaac ctttggtaaa agttggtctt ttcgattcat
     2521 ttgaaaaaaa tcgtcaaaaa gtatttaata acttagctaa tctatttgaa tttgtgaaag
     2581 agttgggaag tttgtttgga gatgctattt atagttggca ggaatcggaa gattggacgg
     2641 aacaagaaaa attttatatg gaacaagagc ttttagggat aggtgtcagc aaacatccac
     2701 tacaagctat tgcaagtaag gctatttacc cgattacccc aatcggaaat ttgtcagaaa
     2761 atagctatgc tattattttg gttgaagttc agaaaataaa agtgattcgt accaaaaagg
     2821 gtgaaaatat ggccttctta caggcagatg atagtaagaa aaaattggat gtcactctct
     2881 tttcagactt atatcgtcag gttggacagg aaataaaaga gggagccttc tactatgtaa
     2941 aaggaaaaat acaatcacgt gatggccgtc tgcaaatgat tgcacaagaa ataagagaag
     3001 cagttgctga acgcttttgg atacaggtga aaaatcatga atcggatcaa gaaatttcac
     3061 gtattttaga acaatttaaa ggcccaatcc cagtcatcat ccggtatgaa gaggaacaga
     3121 aaaccatcgt ttctctccat cattttgtag ctaaatccaa tgaattagag gagaaattga
     3181 atgaaatcgt tatgaaaacg atttatcgct aaaaatacgg aaaatagaag aattttaaaa
     3241 tcaaatgtga tataatcaag aagaatgtta aaagaaaaag gagcataaac caatatgaaa
     3301 cgtattgctg ttttgactag tggcggagac gcacctggta tgaacgctgc tatccgtgca
     3361 gttgttcgtc aagcaatttc agaaggaatg gaagtgtttg gtatctatga cggatatgct
     3421 ggtatggttg ccggtgaaat tcatccccta gatgcagctt cagtaggaga catcatttct
     3481 cgtggtggta cttttcttca ctcagctcgt tatccagagt tcgctcaact tgaagggcaa
     3541 cttaaaggga ttgagcaatt gaaaaaacac ggaattgaag gtgtagttgt tatcggtggt
     3601 gacggatctt accacggcgc tatgcgtttg actgaacatg gcttcccagc tattggtctt
     3661 ccaggtacaa tcgataacga tatcgttggt actgacttta caatcggttt tgacacagcg
     3721 gttactactg ccatggacgc tattgataag attcgtgata catcatcaag tcaccgtcgt
     3781 acttttgtaa tcgaagttat gggacgtaac gctggtgata tcgctctttg ggctggtatt
     3841 gcaactggtg ctgatgaaat catcatccct gaagcaggct tcaagatgga agatattgta
     3901 gcaagcatca aagctggtta tgaatgtggt aaaaaacaca atatcatcgt cttagctgaa
     3961 ggtgtgatgt cagcggctga atttggtcaa aaacttaaag aagctggaga tacaagcgac
     4021 cttcgtgtaa cagaacttgg acatattcaa cgtggtggtt ctccaactgc gcgtgaccgt
     4081 gttttggcgt cacgtatggg tgcacatgct gttaaacttc ttaaagaagg tatcggtggt
     4141 gttgcggttg gtattcgtaa cgaaaaaatg gttgaaaatc caattcttgg tactgcagaa
     4201 gaaggggcat tgtttagcct tactgcagaa ggtaagattg tggttaacaa cccacacaaa
     4261 gccgatattg agctatctag cttgaataag agcttgtcat aatttacaat ttagttaata
     4321 agaccaaaaa ggtcatatat ataaaggagt cacaaaaatc atgaacaaac gtgtaaaaat
     4381 cgttgcaact ttgggtcctg cggtagaaat ccgtggtggt aaaaaattcg gtgaggacgg
     4441 atactggggt gaaaaacttg atgttgaagc ttcagctaaa aacattgcta aattgattga
     4501 agctggtgct aacacattcc gattcaactt ctcacacggc gaccaccaag aacaaggtga
     4561 gcgtatggca actgttaaac ttgcggaaaa aattgcaggt aaaaaagttg gtttccttct
     4621 tgatacaaaa ggacctgaaa tccgtacaga attgttcgaa ggtgaagcta aagaatattc
     4681 atacaaaact ggtgaaaaaa ttcgtgttgc aactaaacaa ggaatcaaat caactcgtga
     4741 agtgattgcg ttgaacgttg ctggtgctct tgatatctat gatgatgttg aagttggtcg
     4801 tcaagttttg gttgacgatg gtaaacttgg tcttcgtgtg gttgctaaag atgatgcaac
     4861 tcgtgaattt gaagttgaag ttgaaaacga tggtatcatc gctaaacaaa aaggtgtgaa
     4921 catccctaac actaaaattc ctttcccagc tcttgctgaa cgcgataacg acgatatccg
     4981 tttcggtctt gaacaaggta tcaacttcat cgcaatttca ttcgtacgta ctgcaaaaga
     5041 tgtgaacgaa gttcgtgcaa tctgtgaaga aactggaaac ggacatgttc aattgttcgc
     5101 taaaatcgaa aaccaacaag gtatcgataa cttagacgaa atcatcgaag cagctgatgg
     5161 tattatgatt gctcgtggtg atatgggtat cgaagtaccg ttcgaaatgg ttccagttta
     5221 tcaaaaaatg attatcaaga aagtcaatgc tgcaggtaaa gttgttatca ctgcaacaaa
     5281 catgcttgaa acaatgactg aaaaaccacg tgcaactcgt tcagaagtat cagacgtatt
     5341 caacgctgtt atcgacggaa ctgacgctac aatgctgtca ggcgagtctg caaacggtaa
     5401 atacccactc gagtcagtaa ctacaatggc tacaatcgac aagaacgctc aagctcttct
     5461 taatgaatac ggacgtcttg attcagattc atttgagcgt aactctaaga cagaagtaat
     5521 ggcttctgct gttaaagatg ctactagctc aatggatatc aaattggttg taactcttac
     5581 taagacaggt catactgcac gtttgatttc taaataccgt ccaaatgctg acatcttagc
     5641 attgacattt gatgaattga cagaacgtgg cttgatgttg aactggggtg ttatcccaat
     5701 gttgacagat gctccatctt caactgacga tatgttcgaa atcgctgaac gtaaagcggt
     5761 agaagcaggt ctcgttgagt caggcgatga tatcgttatc gttgctggtg tgccagtagg
     5821 agaagctgtt cgcacaaaca caatgcgtat ccgcacagta cgttaagaaa aatataaaaa
     5881 cctatcatat ccagctttct agcctgtatg atgggctctt tttttgtcca gggggcaaaa
     5941 ctttcataat ggattgatac tcttcgaaaa tcaaattcaa accacgtcag cgtcgcctta
     6001 ccgtactcaa gtacagcttg cggctagctt cctagtttgc tctttgattt tcattgagta
     6061 tgaaataaga tatgtacaaa ttgattagaa agtcaaatga atttctacaa atgttttagc
     6121 aatcgcaatc tacttgtcta gattcgatct gatatatttt cgatttaatg atatggtatt
     6181 taaaacctcc aaagtagctt gctccattct tttacttacg tgagtgtaga tgttatttac
     6241 tgttttagcg tttttgtgtt ccactctaac cattatagca ttcttctcag ctagtgtact
     6301 aaggagtgtg tgcctgaaaa tatgggaact aaggggctgg tttatcggtt tctctagttt
     6361 agtatttgcc ttttgcaaag tgatcttaaa agcctttctc taaatttaca tatcactatt
     6421 gtttaacaaa atctaatcta ttttaggtca cttattcttt ttttgaaatg tagaatgaac
     6481 tttttcaaag tttttcgaat cttttaaaat ctgtttgttt tatatcgcca ttctcccccc
     6541 ttttttaatt ctccctatat agcctgacaa ctttcccgat ggtacgaata tggttgcttt
     6601 cgtctaggtg gatgtcgggg tattcgggat tgagtttttt tgaggtagcc ttggcggagt
     6661 ttcttgacat agttagcgcc gtctacttgg aagatgccga tggtattata gtcaatctgt
     6721 ggggtattct tgataaatag gtagtcgctg tttcttatct ttgcctccat ggacttgctg
     6781 acgacataag cgattgggtc gtagtcgtct gggataatgg aaactccata actaaatcgt
     6841 cgtcctgcat cgagcggcta cctgcagaga taaactacct aacacgagag taagtagtct
     6901 gtctgtagtc gtccagtctg atgattttta cgatacttcg tttttctgct tatacagttg
     6961 cctctaggca taggttagga ctttaccttg tctgggtggt gcccgttggt cgtagataga
     7021 ttggatatcg ctaggagaat ccttttgaac tggaggaaag agggcatcaa tcaagctact
     7081 gaatacttta actaagtcaa atatagtatt tttcttagta gacctaaccc ttttttcata
     7141 atttctaatg gtgtttttac ttatacctat cttagtaccc aattcttatt gagtccaacc
     7201 attactagtc tatattgttt tatagttgat tgagtttgga atagtacgct gtagctgcta
     7261 aaacatttct aggaattaat ttgcctttcc taatagagtt gttcatatct tatttcaatc
     7321 tattatattt ttcgcctcta acaatcgcaa tctcttcttt atctacgaac gaaatcgctt
     7381 tctatttttg taagtaaagc atcacacgaa atccacgaaa atgaaaacct ttgttgtgtt
     7441 ttcgtaaaaa atttgttgac agagcacgaa acgcctacta taattaaatc aagtttaagg
     7501 aaataacaaa aaaacaaatc ggagggaaag acgatgaaca cattaaatga gaaagtaatc
     7561 aatatctgta aagcagtagt taaagaaact ttaatccaag acatttagga gaaagaaatg
     7621 aagaaatcaa gaaaattagc cacattagga atctgttcag ccttgttttt aggcttggct
     7681 gcttgtcaac aacaacatgc tacttctgag ggtacgaatc aaaggcaaag cagttcagcg
     7741 aaagttccat ggaaagcttc atacaccaac ctaaacaacc aggtaagtac agaagaggtc
     7801 aaatctctct tatcagctca cttggatcca aatagtgttg atgcattttt taatctcgtt
     7861 aatgactata ataccattgt cggctcaact ggcttatcag gagatttcac ttcctttact
     7921 cacaccgaat acgatgttga gaaaatcagt catctctgga atcaaaagaa gggcgatttc
     7981 gttgggacca actgccgtat caatagttat tgtcttttga aaaattcagt caccattcca
     8041 aagcttgaaa agaatgacca gttgcttttc ctagataatg atgcgattga taaaggaaag
     8101 gtctttgatt cacaagataa ggaagagttt gatattctat tttcgagagt tccaactgag
     8161 gcaactacag atgtcaaggt tcacgctgaa aagatggaaa cattcttctc acaatttcaa
     8221 ttcaatgaaa aagctcgaat gctgtctgta gtcttgcacg acaatctgga tggcgagtat
     8281 ctgtttgtag gccacgttgg ggtcttagta cctgctgatg acggtttctt atttgtagag
     8341 aaattgactt tcgaagagcc ctaccaagcg attaaatttg ctagtaagga agattgctac
     8401 aagtatttgg gcaccaagta tgcggattat acaggcgagg gactggctaa gccttttatc
     8461 atggataatg ataagtgggt taaactttaa tagtgttatg atatgacagt aatcttagga
     8521 tttttatttc tatttttgat aagttggtgg gttatttcaa tcgttaatag ccagaaacca
     8581 cgcaaaaatg aaacatttat tggctatgtc caaagatacg atattgatgg gaatggctat
     8641 caatcattac cgtgtcctca gaactgagag gagttcttga aatcgtaaaa ccactttgaa
     8701 caagagttac ttcaacccat tggctccgac ggattaagtt gctttcgtga ataccaaaat
     8761 cagccgcaat ttgttcataa gtgcgctatt ctcgcacata ttgaagagtg gccataagaa
     8821 ggtcttctag gcttaattta ggttttcgtc caccttttgc gtgtttaagt tgataagctg
     8881 tttttaatac agctaatatc tcttcaaaag tcgtgcgctg aacaccaaca agacgtttaa
     8941 atcgtgcatc agttagttgt ttacttgctt cataattcat agaactacta taccatattt
     9001 tgtttcgcag gaagtctaat gctaaaatct tatcagtgag aagatttctt aaagtttatt
     9061 ctttgtagtt tcatctgtat tagtacataa tttaacttag agaaaatagg aggactaatc
     9121 gaatggaatt aaaagatttt acagaaaaag aacaggaaat gattaagaaa aggcttacaa
     9181 tgtctaatat tagtgacaaa gaaactactg agaagattct ggcgctagtc ccacaagact
     9241 tgattaagcg aatcccgttt tttgtcagaa aacatgctac aacacgtacg attaaacgca
     9301 tttcaattga ataccctgaa ctctacgctg tagctcaaac aagtggtgag attccagaaa
     9361 aaaacgcgaa gaattgcgtc agattatcac aactatcttt gaacaaaaga tgaataagca
     9421 tagtattaag tagagaatga aaaaatattt tattggcggt ttgggaagca atgcctatca
     9481 tagcaaggat tttcttcaag aactagattc gcaggtctat tttctaaatc catatgaaaa
     9541 gcatcttcga gatgaaacag aattgaaatc atggtttaaa aatgagattg tagaggaaga
     9601 atctatctgt ctgataggtc attctattgg aggcgattta gctcgttatt tcgcatcgga
     9661 atttgaagaa gtaaagaaac tgattctttt ggatggtggc tatctagatt tagataagat
     9721 tttacctttg gatacagagt tagaggaaac taaaaattat atcaaatctc aaattatttc
     9781 ggacttagat gttcttactt ctaaagaaaa atctgaagca aagcattggt cagaaaatat
     9841 ggagaaagct gtaagacagt cctatcactg gaatgttgag tataatagat atgagttggc
     9901 tataaattat gaaaatatag aagcgatact ccgcctacgg agaaaaatac aagcttttaa
     9961 gagagaagtg ggagatacct tgtttattag tcctcgctat cctaatgaag ctacatggag
    10021 agaggaagcc ctaaaagaat tgccagacta ttttgatact atttttttag aaaactttgg
    10081 ccatgagctt tatactcaag cacctaaaga aatcgctagt ctaatgaatg agtggctcgc
    10141 ttattttcta tgagctactt gtattgctgg aaatggtata agatgaaaat ctacaagtca
    10201 ctaattttca tataaccaaa aaacgaacag gctctttttc tgttattcag aagagaactt
    10261 gttcgttttt atcttgattt tcttaaaaag ctctatatac atagggattt tctggtttat
    10321 cgactttggt aaagctgtcg atttccaagg ttggaaggtt ttgtttgagt tctttatggt
    10381 agtgattgac cagttttcct ttggctgaaa tccaagtgtt gttttcatac tgccgggtat
    10441 tgcccttggt cagcaatcca tagacaccag aatctgcgat gcagtgaata atgccgaagc
    10501 ggaacagaaa ttggctattg gcatgactgg ggtcattata gacaaagcct gtgaactgga
    10561 ttgtcttacc ctcaaattca tctggatagt cgtagatagc ctccatgacc tccatatagt
    10621 tttcattagt gatctgaata ctatcttggg ataagtattt atccgccgcc gttcgcattt
    10681 ccttttcata ggctgatttt gaaaaataag aactggtatc tggtttcaaa tattggcttg
    10741 tcgtcccttc gcttgtctga atggctagat ccgttccttc cgataggggg aaatgataac
    10801 ctttagcaga aacggtctga gaatccaagc taacagttgg gaaagttaag ccgatgacaa
    10861 gtggaatagc cagaagagaa atactcgtca tcttggctaa tcggctgttc agatgactgt
    10921 gggttttgac ttgcttcatc cagatataca attgaacgat agccaagata aaagaaagca
    10981 ccatggagat ataggccaga taggaatagt gcatgttgat gtactggttt agtttgcccg
    11041 acagatggag gtaaatagtc agttcaaaat agccagctaa aactaaaaat cgaatcatag
    11101 gatgactcca atcaagagag aatagactaa gacgacaaga gttacaattg ttatgaagtg
    11161 actgataaat cgtgctttca agtaattttt catcatgaga atatttttga tatccagcat
    11221 tggaccaatg acgagaaagg ccagaactgg tgccaaaccg aaactcgaga gaagagaagc
    11281 acctataaag gcatccgcct cactacagag cgaaagaaga aaggctaaaa tcatcaagag
    11341 caggatggca aaaagagggg tcgcactgat agaggtcaga atccgagtcg gaacgtagac
    11401 ctgtattata gaagcaaaga ggcagccaaa taccaaataa cgccccgtat caaaaaattc
    11461 atcaatggcc tgcacaaaga cttgaaaaac tttttttgca gaactcaagt aagaaaaatc
    11521 atgctcatga caagccagac gattttcttt ctgaatcggt tcttgccaga aaaatcctag
    11581 aaaaattcct agtattacag ccacaagaat ggaacccaga gctcgtaata gggcgacatg
    11641 gaaggagttg ccaaaggcag aataggtcgc aaaaagaaca atgggattga taacaggtgc
    11701 tgtcacaaga aaaggaacgg ccgtgtaact tggaaccttt ttttccagaa aacgattgat
    11761 gatggggacg attccacatt cacaagaagg gaaaaacata ccgacgaagg tcccaaaaaa
    11821 gattctcccc caacgatttc gagggagaaa atgataaacc ttgtcaggtg tgatataaac
    11881 ttcaatcagc cctgagacaa tgcttcctat cagaacgaag ggaagggctt caatgataat
    11941 ggagagaaaa atggctccag tttgaagtac actagatggg agttgttgaa aagcagtcat
    12001 ctagtttttc ttttctgctt tggctttttt ctctttgtca tcagggaaag taacttgttt
    12061 caaatcaggg agtttagcaa actcttcaaa catcttgtcc aagtcgtctc gttttgtaaa
    12121 tttgacagcc ataggtgtac ctcgattcta aattctacct ctattatact attattttgc
    12181 ggaaaaggga gttttttaat ttgttttcga tagttgatac acttcgaaaa tctcttcaaa
    12241 ccacgtcagc ttcgccttac cgtagtacgg tt
//
LOCUS       DAVKXA010000054        12098 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKXA010000054 DAVKXA010000000
VERSION     DAVKXA010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12098
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.054"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(134..1336)
                     /gene="rpsA"
                     /locus_tag="VW883_001774"
     CDS             complement(134..1336)
                     /gene="rpsA"
                     /locus_tag="VW883_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0274868.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1498..1569)
                     /locus_tag="VW883_001775"
     tRNA            complement(1498..1569)
                     /locus_tag="VW883_001775"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1535..1537),aa:Gln,seq:ttg)
     gene            complement(1579..1659)
                     /locus_tag="VW883_001776"
     tRNA            complement(1579..1659)
                     /locus_tag="VW883_001776"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1623..1625),aa:Tyr,seq:gta)
     gene            complement(1709..1939)
                     /locus_tag="VW883_001777"
     CDS             complement(1709..1939)
                     /locus_tag="VW883_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0274869.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2107..2751)
                     /gene="pcp"
                     /locus_tag="VW883_001778"
     CDS             complement(2107..2751)
                     /gene="pcp"
                     /locus_tag="VW883_001778"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0274870.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2766..3689)
                     /locus_tag="VW883_001779"
     CDS             complement(2766..3689)
                     /locus_tag="VW883_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0274871.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3686..4375)
                     /locus_tag="VW883_001780"
     CDS             complement(3686..4375)
                     /locus_tag="VW883_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0274872.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4440..5144)
                     /locus_tag="VW883_001781"
     CDS             complement(4440..5144)
                     /locus_tag="VW883_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0274873.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIIDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDILTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5200..6222)
                     /locus_tag="VW883_001782"
     CDS             complement(5200..6222)
                     /locus_tag="VW883_001782"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0274874.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6354..8825)
                     /gene="parC"
                     /locus_tag="VW883_001783"
     CDS             complement(6354..8825)
                     /gene="parC"
                     /locus_tag="VW883_001783"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0274875.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9245..11188)
                     /gene="parE"
                     /locus_tag="VW883_001784"
     CDS             complement(9245..11188)
                     /gene="parE"
                     /locus_tag="VW883_001784"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0274876.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11324..11965
                     /gene="plsY"
                     /locus_tag="VW883_001785"
     CDS             11324..11965
                     /gene="plsY"
                     /locus_tag="VW883_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0274877.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3481 a         2741 c         2132 g         3744 t
ORIGIN      
        1 ctgaatatca aaaaagaaag gacaaaattt gtcctttctc aagcttagct tttcttcaac
       61 ccactacagt tgacaaagag ccaataaaat tccttgttta gtaaacaaag gattttgtga
      121 attttcaatt tgattaaagt tcgatatcac caaacaaatc agccattgaa aatcctgttt
      181 gtgtttctgg aagttcgaaa tcacgctttt cttgacgtct tggacgacgt ggacgagcag
      241 cacgtttttc ttctttttgt ccttcttctt gggctggacg ttcttcaaga gctttaatag
      301 aaagtgacac gcgttctgca tctgcgttaa cttcaagaac tttaacttga acttcttgac
      361 caactttaag agcttctttt ggattttcaa tccgtttgtg tgaaatttgt gatacgtgaa
      421 caagtccatc gatacctggc aatacttcaa caaatgcacc gaagtcagtc aaacgtttaa
      481 ctgttccttc tactacatca cctttagcca atttttgctc aacgccatcc catggtcctg
      541 gtactgttgc tttaagtgaa agtgatacac gtccttcttc ttcgttaaga tcaaggattt
      601 tcacttcaat ttcttcacca acagttacaa ctgattttgg tgatacgtta cgttcatgtg
      661 acaattcagt caagtgaacc aatccgtcaa caccaccaag gtcgatgaaa gcgccgaagc
      721 ttgtgatacg agcaacttta ccagttacaa catcaccaac agccaattta ccgaatactt
      781 cagcgcgagc tgctgcagta gctgcttcaa caacttcacg acgtgaaagg atgaagcggt
      841 tttctttagc gttaacttct ttgattttag tatcaaattc ttgacctaca aaacgctcag
      901 cgttacgtac gaaacgagta tccaacattg aagctgggat aaatccacga acaccttcaa
      961 attctactga aagtccacct ttaacggcac gcgttccttt aacagtaaca acttcttctt
     1021 cgcgaccaac aagtttgtcc catgctttgc gagcttcaag gcgtttttta gatacaaggt
     1081 atgtaactgt atcagtatct ttaccaacta cttgacgaag tacaagaaca tccaatactt
     1141 ctcctacttt aacaaagtca ttgatatctg catcacgatc gtttgtcaat tcgcgaagag
     1201 tcaagacacc ttcaacacca gttccagaga ttgcaacgtt agcttgagtc gcatcaactg
     1261 tcaatacttc agcactaaca acatcaccag tctcaacttg actaacgcta tttagcaaat
     1321 cttcaaattc gttcatctaa aaaatcctcc aacaatcaag tttttcttaa acttgacata
     1381 cttataattt ttttcctaag cacccgcaag gacatgttca tatcattcac gtctttcaat
     1441 tataaaaata aaatacccta agatattttg ctttttatct tgattattac ctaagaactg
     1501 gggtagctgg attcgaacca acgcatgagg gagtcaaagt cccttgcctt accgcttggc
     1561 tataccccat taatgaaatg gagagagagg gattcgaacc cccgaacccg aaggagcgga
     1621 tttacagtcc gccgcgttta gcctcttcgc tatctctcct acaatcaata tggactatta
     1681 tatcatgaaa atttcaaaaa aacaagactt attttgctaa attataattt tcaatcaaaa
     1741 tttccacagc tttttccaat tttttataaa aactatcgac attcccattc tttataatgg
     1801 caaattgtcc gtctaattcg gcaatttctc cgataacttt tttaccgata gtcaatgtat
     1861 aaccttcaaa actgtcttta ccaacattaa ctttggcatc cgctacttga atttcgattt
     1921 ttttatcttt cttgctcatt tcatacctct cttcactttt tctattttac aagaaaatcc
     1981 taaaactagc aagaaaaaac tctatatcag gcttctctga tatagagttt tatgtaaaca
     2041 acctcaatcg atttagcata gctaatagtt agtaaacaag cataattgac tatccttttt
     2101 aggttatcag tgagtctcac cgcctactaa ctgcaaatcc ttatctttgt agtctacaat
     2161 agcttcaata gctacctcta tgcctcttac aatatcacat agactcattc ctgcagtatt
     2221 cggcttattt actacttgtt ccatcatata tggaatatgc atgaaacctg ctctcatatt
     2281 agggaatttt ttatccacta aataaagagc ttggtacatc aaatgattgc aaacaaaggt
     2341 tcctgcacta ttggatacaa ctgccggaag tccctgtttt ttgatagctt gtaccatcgc
     2401 tttgataggt aaactactaa aataggccga tgctccatca atacgaatcg gtgtatcaat
     2461 tggttgattg ccttcgttat caggtatgcg agcatcatct tgattaatag ccactcgttc
     2521 aggtgttaag ccggtcctgc cgcctgcttg tccaatacaa agtacagcat ctggttgata
     2581 tcgtaatatt tctgcctcta aaacttctga cgacttataa aaaaccgttg gaatttctac
     2641 ccagcgaact tcagccccat taatctcaga tggtaataat tttacagcct ccaaagctgg
     2701 attaatcttt tcacctccaa aaggattaaa acctgtaacc aatattttca ttttattttc
     2761 ctttactaaa atgcgagaaa gtacattaag aatatgtgaa taacaatcat tactagagca
     2821 acacctgctt gagcctttat aacgccattc tgatctttca tatccatcaa tgctgctggt
     2881 agagcgttaa aattagcagc cattggggtc aataaggtcc cacaataacc tgctgtcatg
     2941 gcaagagcac cagccacaat tggattagct cccagagcaa atacaaaggg aactccaaca
     3001 cctgctgtaa taacggtgaa tgctgcaaaa gcatttccca taatcattgt gaatagaacc
     3061 attccaagaa cataggccaa aactcctata aagcgactat ctgaaggaac aataccgcta
     3121 atcagatgag agataacatc accaacacct gctacagtaa aaatagcccc caaagcccct
     3181 aataattgag gaacaatccc acttgttgaa acttgctgag tcattcgatt attttctgat
     3241 aacagactct tagggtgact attggtaatc acaagaacag aaattgtagc aaacaaggcg
     3301 gcaaggctaa tcgaaatctt gctaaattct ggaatcattt gcgctaagac caacgcaagt
     3361 attgccatca gcataactgg aataaaaatt ttatttttca acctgttaga ttcaatattg
     3421 gctttcattt catctaagga tggcaaggtt ccgatacgga cttgcttaaa caatgttaac
     3481 agcgataata ggattacaat aataccaata ctcatatttg gcatatagga accacctata
     3541 aacgtaatag acaatagagt ccaaaatgca gatgtcccaa gtcgaactgg gtttgtttta
     3601 tctttataac tacaataggc tgtatggaga aattgacaac caatcacaat ataggtcaac
     3661 tctaatagtt gctttgccaa ctctgtcatt tttgttctcc tcccctagtc ttttttgata
     3721 tcaatttttt atcaaataaa taattgtaaa tccccactac aataagtgtt ataacagcaa
     3781 caataataga tgtagaagca atccctgcat aattgctttc atagcctaac tgatctaatg
     3841 ttccccctat caagaggact cccccagcac ctacaaacgt attttgagca aagaaatttc
     3901 caaaattttc attcgcagcc gcacgcgctt ttattgtctc atcttcaacc tctgttaact
     3961 ttctacctaa ttgagactct gcagctgctt ctcccatagg ttgaaccaaa ggtctgacaa
     4021 actgagggtg tcctcctaga cgaattgaaa agaaaccagc taactctcga ataaagaaat
     4081 aaactgtata gaagtttcca actgtcagac ctttaatctt tcgaatcaaa tcgattgatc
     4141 gttgcttgag tccaaaggtt tctgacagcc ccacaagagg caaggtaacc ataaaaatcg
     4201 tgagcactcg ctgattgcta aattcttttc ccaaaatctc caaaaattca acgagagaaa
     4261 cacctgaaac taaagctgta accaaaccag ctaagactac tgttgcaatt gtatcaaatt
     4321 ttaaaataaa acccacaaca atgattgcta ttcctattaa tctaatccac tccatatcaa
     4381 actcctttat attcaaaatg acagtatttt taaaatttta tcaagatcaa taccatttct
     4441 tatttaatgt gtttttctag ttctttttgg tatttgctat tggattccaa tttttctttt
     4501 tgccattttt taaaaacctc gttatattct tttgttgtaa gaatatcttt ttgcaatttc
     4561 attcctttaa agatatatgg atccccctta ataccaactt gtgagtatgg ttttgagaat
     4621 ggtactacgt tacttacaac tggagaacca ccagatgaag ctgttggcat caataatgaa
     4681 ctatctgtcg accaagcttg agctttggca tatttttcat atcttttctc taggtcagtg
     4741 gtctcagaaa cagcatcttc taacaatttc ttatatttat ccaaaccagg tttagctaca
     4801 acatccttat cttttccttt cgtaatacca aggtgtttca tggcagaacc agattttgga
     4861 tctataatat tcaagtaaga cgctggatct tgatagcttg gagcccatcc tgtactattc
     4921 aaatcatagt ctttttgaga aggagcaaca ttgccgtatt tatcattttc catcaaacca
     4981 tcaataacat ttccaataac gtctgtcgtc gatgttcgag tcgctatact gtagcccaat
     5041 gatgctggat ctactgcata gacataagaa aatgttgtcg gtgcatctgc ttctttatca
     5101 gtttttccac aagccactaa aatagctgac gtgctcagga ccactcctgc tgttaagagc
     5161 cactttttct atttcataaa aaatctcctt tggtttattt taatctactt ttacaatcca
     5221 accttctggc gcttcaatat cgccaaactg aatacccgtc aattcattat ataatttacg
     5281 cgtcacagga cctacttctg tttcactata gaatacatgg aaatcatcac catgttgaat
     5341 acctccaatt ggagaaataa ccgctgctgt accacaggca cctgcctcta caaaacggtc
     5401 aagattatca attggaacat caccctcaat aggagttaat cccaagcgat gttctgccaa
     5461 ataaagcaag gaatacttgg taatagatgg caagatagat ggactcaatg gtgttacaaa
     5521 ttcattatca gctgtaattc caaagaagtt agctgatccg acttcttcaa tctttgtatg
     5581 agttgatggg tccagataga taacatctga gaaatgacgt gacttggcca tttttcctgg
     5641 taagagactt gcagcatagt ttccaccaac cttagccgca cctgtaccat ttggtgctgc
     5701 acggtcgtac tcatcctgaa tcaagaagtt ggttgggacc aaaccacctt taaagtaatt
     5761 tccaactggc atagcaaaga tggtgaaaat gtattcttct gccggtttta ccccgataat
     5821 atctccgaca ccaatcaaaa gagggcgaag atataaggtt ccacctattc cgtatggtgg
     5881 tacgtattct tcattcgcac ggacaactgc tttacaagct tctacaaaca tgtctgtcgg
     5941 aacttgtggc atcaagagac ggtcacatgt acgttgcagg cgtttagcat tttcatcagg
     6001 acggaacagt tgaacactgc catccttagt acgataagct ttcaaacctt caaatgcttg
     6061 ttgtccatag tgaagacttg gagaagactc tgaaatatgc aaagttgcat cctctgtaag
     6121 ctctccttga tcccattgtc catttttgaa atgagcaaga tagcgataag gtaatttcat
     6181 ataggaaaaa ccgaggtttt cccaatcaat cgttactgtc atattccact ccttattcta
     6241 aaaacctatt tcttatattc tacactattt ttctaaaata gcaagtatat tttgtaattt
     6301 tcagaaaatt tctccaataa aaaccagctc ttagaactga ttcttcattt cacttattta
     6361 tcttcagtaa ctacttcctg aagataagcg tcaaaaactt cttcatctga aatcgtgtca
     6421 gaaatgaagc ttccattgct agtgcgttct gacaagttca agtcttgcaa tcggctttca
     6481 tagattgttc ctttattgga ttggacaagc agagtttggt cgttcacatc cacttccgta
     6541 ctgaagaaat cgccaacaaa tccttgctct gcaactgctc ctgccaagaa gacacgatgc
     6601 ggtttgtttt tcaactcacg caagacttgt aatcctcgtt tggcacggct ggttgctaga
     6661 atttcctcaa tggaaacacg tttcaagctt ccacgctggg tcaagaggta gaaggacgaa
     6721 gtattacaga taaagccaga ttggaggaca tcatcttctt tcaaattcat agccttgaca
     6781 cctgctgcct tagcaccgac aaccggaacc tcttcgatat tgaaacgcag ggcataacca
     6841 ttttgactaa ccaagacaac atcatctagt ttaatcggag ccactgctac aatctgatct
     6901 gtatcgtctt tgagcttagc atacttgaca gacttagatc tataggtccg ccatggagtg
     6961 aattcttttc gctctacccg tttgatttga ccaaggcgag tcactgcaaa gtaggttgtc
     7021 gcatcgtcaa actgatccag tacttccaca taaaggattt cttcattcgt ttcaaagttt
     7081 gtgatggttt ggctcagatg ctctccgatg tccttccaac gaatatctgc caactcatgg
     7141 attggtctgt agatgacatt tccaagactt gtgaacatca agaggtgctg ggttgtcttg
     7201 gcagattgaa caaaaatcaa acggtcatca tcacgcttgc caatttcttc caaggtggaa
     7261 gccgcaaagg aacgtggact ggtacgcttg atgtaacctg ccttggtcac gctgacgtag
     7321 gtatcttcct cagcgataag actagctgta tcaatctcaa ttgctttcgc agtgtcttct
     7381 aaagaactca aacgaggagt tgcaaatttc ttcttgacct cacgaagttc tttcttcatg
     7441 agattgtaca tagtcctttc atcaccgata atagccgcca gcatagcaat cttctcacga
     7501 agctctgctt cttcttcctg caagacaacc acatcggtat tggtcaaacg gtacagttgc
     7561 aaagttacga tagcctcagc ctgttcttcc gtaaaatcat agctaacttt gaggttttcc
     7621 ttggcgtccg ccttattctc agaagcacgg ataagagcaa tgacttcatc caaaatcgaa
     7681 atcacacgaa tcaaaccttc gacgatatgg agacgtttct cagccttttc tttgtcaaag
     7741 cgtgaacgcg ccaaaatcac ttctcgacgg tgagcgatgt agctagacag gattggaaca
     7801 atcccaacct gacgaggtgt gaaattgtca atcgccacca tattaaagtt gtagttgatt
     7861 tgtaggtcgg tgtacttaaa taagtagttg agaacaagct cagtattagc gtctttctta
     7921 agttcgatag cgatacgaag accatcacgg tcagactcat cacgaacctc agcaatccca
     7981 gctaccttgt tattaacacg aacatcatcg attttcttga ctagattggc cttattgatt
     8041 tcataaggaa tctcagtaat aacgatttgt tccttaccac cttttagctt ttcaatttca
     8101 gtcttggaac gaacaaccac gcgccctttc ccagtctcat aagctttctt gatttcatca
     8161 cgaccctgaa taatagcccc tgtagggaag tctggtccag gcaagaattc catgagttta
     8221 tcaatctttg cagttgggtg gtcaatcatg taaactgcag catctatgac ctcagctaaa
     8281 ttatggggag gaatgtctgt ggcataacca gccgaaatcc cagtcgaacc attgaccaag
     8341 aggtttggaa aggctgctgg caagaccgtt ggttctttct ccgtatcgtc aaagttccat
     8401 gcaaaaggaa ctgtcttttt ctcgatatcc tgaagaaggt agcctgcaat ttcagacaaa
     8461 cgtgcctcag tataacgcat agccgcagga ggatctccgt ccatagaacc gttattaccg
     8521 tgcatttcaa ctagaatctc acgatttttc cagttctgtg acatacgaac catggcatca
     8581 tagatagaag aatccccgtg tgggtggaaa ttccccatga tgttcccgac tgacttggcc
     8641 gacttacggt agctcttgtc aaaagtattg ctatccttat tcatagaata aagaatacgg
     8701 cgctgaaccg gcttcaaccc atcacgaata tctggcaaag cccggtcttg aataatgtac
     8761 ttggagtagc gaccaaagcg ctctcccatg atgtcctcca gggacatgtt ttgaatgtta
     8821 gacataagat acaaagccca taaaatacca agtgaaaata gaaaattctt gaagtaagca
     8881 aactcacaag agaatttatc tttttcacac agtatctagg gcgtgttcaa ctcctttcaa
     8941 agaatgtaga gtaggttttt atgcagtaaa agatatttta cgggaattcc tcccgtgttc
     9001 agttacgata agtaaccaaa ctatcctgtt tgtatttttc aatatgaaaa tctggttttc
     9061 caaaattagt cttagtttgt gtcttagccg ctcccttaag cgcctctttg agataagcac
     9121 tcatagcaga ttcttcatta ataatcctgc aattttttca aaccaagatt ttcaaactgc
     9181 tttttcacat agtcattcac atccgactct aatttccagt ttactaacat attattttct
     9241 ttcattaaaa cactgtcgct tcttctagcg taaacttgac attatcttca atccatttac
     9301 ggcgtggttc taccttatct cccatgagaa cattgacgcg gcgttcggcg cgcgctaaat
     9361 cttcaattgt gacacggatg agggtacgtg tttctgggtt catggttgtt tcccagagct
     9421 ggtccgcatt catctcacca agtcctttgt atcgttggag ggtagcgcct ttaccgaact
     9481 gtttacggag ttcttctagt tctccgtccg tccaagcgta ggccacttct tctttcttgc
     9541 ctttaccttt ggacatctta taaagaggtg ggagggcaat atagacatga cctgcctcga
     9601 ctagcggacg catgtaacgg tagaaaaatg tcaagagcaa ggtctggata tgggcaccgt
     9661 cggtatccgc atcggtcatg ataatgatct tatcatagtt ggcatcttca atagagaagt
     9721 ctgctccaac acccgcacca atggtataaa tcatggtatt gatctcttca tttttgagga
     9781 tatccgccat cttggccttg gctgtattga caaccttacc acgaagaggt agaatagcct
     9841 ggaacttgcg gtcacgacct tgtttggcag aaccaccggc agagtccccc tcaactagat
     9901 agagttcatt cttagcagga ttcttagatt gggctggggt caatttccca gacaacaagc
     9961 ccttatcttt cttgtttttc ttcccatttc ggctctcatc acgcgcctta cgtgctgctt
    10021 cacgagcatc acgggccttg atagccttgc ggatgaggtt agaagctaat tccccatttt
    10081 ccataaggaa aaaggtcaac ttatcagcca ctattccatc cacaactggg cgagctaggg
    10141 ggcttcctag tttatccttg gtctgtcctt caaactgcaa gtgttcttca ggaactaaga
    10201 tagaaagaac ggccgctagt ccctcacgat agtctgaacc ttcaaggttt ttatcttttt
    10261 ccttgagaag acctgtttta cgtgcatagt cattcatgac cttggtaatg gcagacttga
    10321 gtcctgtctc gtgcgttcca ccgtccttgg tgcgaacgtt attgacaaag gatagaatgt
    10381 tatctgagaa tccgtcattg tactggaggg ctacttccac ttgaaaacca ttgtcttccc
    10441 cttcaaagta aagaactggc gtcaagattt ccttatcttc gttgagataa gaaacaaaat
    10501 cttgtactcc attctcatag tggaactcaa tcgcttcatc tgttcgcttg tccgttaaag
    10561 acaaggtcac atttttcaag agaaaggctg attcattaag gcgctctgaa atggtattgt
    10621 acttgaaatc tgtcgtagaa aagatagtcg cgtcaggcat aaaagtaact ttggtgcctg
    10681 ttttagactt gggtgctgta ccgattttct tcaaagtcgt gacaggtttt ccaccatttt
    10741 caaaacgttg cttgtaaact gcgccatcac gggtaatttc aacttctaac cagctagaaa
    10801 gggcgttaac aacggaagaa cccactccgt gaagtccacc tgatgtctta tagccacctt
    10861 gaccgaattt ccctccggca tgaagaatgg taaagataac ctcaacagtt ggaattccca
    10921 tagcgtgcat acctgtcggc atcccacgtc catggtcttg aaccgttaga ctaccgtctt
    10981 tattgatagt tacatcaata cgatcaccaa acccagacaa ggcttcatcg actgcattat
    11041 caacgatttc ccaaactagg tgatgaagac cagcgccatc ggtcgatcca atatacatcc
    11101 ctggacgttt tcggaccgca tccaaccctt ctagcacctg aatagcatca tcattataat
    11161 tgttaatatt gatttccttt tttgacacaa ggaacctcct attcgttcat ctttactatt
    11221 ctacaggttt tccaaggatt ttgcaaaatt tttctttctc cgatgtgaca atttcagcag
    11281 agattctctg cttttctttc ccaattcatg atataatagg agtatgatta caatagtttt
    11341 attaatccta gcctatctgc tgggttcgat tccatctggt ctctggattg gacaagtatt
    11401 ctttcaaatc aatctacgcg agcatggttc tggtaacact ggaacgacca acaccttccg
    11461 cattttaggt aagaaagctg gtatggcaac ctttgtgatt gactttttca aaggaaccct
    11521 agcaacgctg cttccgatta tttttcatct acaaggcgtt tctcctctca tctttggact
    11581 tttggctgtt atcggccata ccttccctat ctttgcagga tttaaaggtg gtaaggctgt
    11641 cgcaaccagt gctggagtga ttttcggatt tgcgcctatc ttctgtctct accttgcgat
    11701 tatcttcttt ggagctctct atcttggcag tatgatttca ctgtctagtg tcacagcatc
    11761 gatcgcggct gttatcgggg ttctgctctt tccacttttt ggttttatcc tgagtaacta
    11821 tgactctctc ttcatcgcta ttatcttagc acttgctagt ttgattatca ttcgtcataa
    11881 ggacaatata gctcgtatca aaaataaaac tgaaaatttg gtcccttggg gattgaacct
    11941 aacccatcaa gatcctaaaa aataaaacgc cagttctgta ctgcccccaa acagttagac
    12001 aaataattta tggctctttg tcaactgtag tgggttgaag tcagctaagc tcgagaaagg
    12061 acaaattttg tcctttcttt tttgatattc agagcgat
//
LOCUS       DAVKXA010000055        11804 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKXA010000055 DAVKXA010000000
VERSION     DAVKXA010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.055"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            180..833
                     /locus_tag="VW883_001786"
     CDS             180..833
                     /locus_tag="VW883_001786"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0274878.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            843..1307
                     /locus_tag="VW883_001787"
     CDS             843..1307
                     /locus_tag="VW883_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0274879.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1320..2588
                     /locus_tag="VW883_001788"
     CDS             1320..2588
                     /locus_tag="VW883_001788"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0274880.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKFNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2602..2862
                     /locus_tag="VW883_001789"
     CDS             2602..2862
                     /locus_tag="VW883_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274881.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2873..4234
                     /gene="pdrM"
                     /locus_tag="VW883_001790"
     CDS             2873..4234
                     /gene="pdrM"
                     /locus_tag="VW883_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0274882.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4388..5356
                     /locus_tag="VW883_001791"
     CDS             4388..5356
                     /locus_tag="VW883_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0274883.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNVEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5372..6364
                     /locus_tag="VW883_001792"
     CDS             5372..6364
                     /locus_tag="VW883_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0274884.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6582..7625
                     /locus_tag="VW883_001793"
     CDS             6582..7625
                     /locus_tag="VW883_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0274885.1"
                     /translation="MVDDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7689..9374
                     /gene="lpdA"
                     /locus_tag="VW883_001794"
     CDS             7689..9374
                     /gene="lpdA"
                     /locus_tag="VW883_001794"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0274886.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9438..10427
                     /locus_tag="VW883_001795"
     CDS             9438..10427
                     /locus_tag="VW883_001795"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0274887.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEITEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10500..11570)
                     /gene="xerS"
                     /locus_tag="VW883_001796"
     CDS             complement(10500..11570)
                     /gene="xerS"
                     /locus_tag="VW883_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0274888.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGIS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAKNIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
BASE COUNT         3501 a         2211 c         2647 g         3445 t
ORIGIN      
        1 agtaaaatgc ttaatgattt aaaaagtaat tataaaaaat agccagtctt tataaactgt
       61 attcacgtat tcaaatcgta tatatagtcg atttattaaa tctttagata aactgtaaaa
      121 agtggtttcc atagccactt tttgctataa tagaggcagt aaaaatgaag gagtcggcta
      181 tggaacactc gtcttggcat gctttgatta aggcgcaatt acctgagggt tatttcggga
      241 aaatcaatca gtttatggag caggtctatt ctcaggggat tatttatcca cccaaggaaa
      301 aggtttttca ggctctcttg acaacactgc ttgaagaagt taaggtggta attctagggc
      361 aagaccccta tcacggacca ggtcaagcgc agggcttgag tttttctgta cctgactcta
      421 tcccagctcc accatccttg caaaatatct tgaaagaatt gtcagatgat atcggagtta
      481 agaaatctca tgatttgaca gcttgggctg agcaaggagt cttgcttctt aatgcttgtt
      541 tgactgttcc tgctggacag gccaatggtc atgctggtca aatctgggag ccttttactg
      601 atgctgtgat tcaggtggtc aatcatctag atagaccagt cgtttttgta ctctggggag
      661 cttatgcacg taagaagaag gcattagtta ccaatcctca tcacttgatt atcgaatcag
      721 cccatccaag tcctttgtcg gtttatagag gattttgggg ttccaagccc ttttccaagg
      781 ccaatgcatt cttaaaagag acaggacaag agccaatcga ttggcttaga taaggagaaa
      841 atatgcctca gttagcgacg atttgctaca ttgataatgg gaaagaactg ctcatgctcc
      901 atcgtaataa gaaacccaat gatgtccatg aagggaaatg gattggtgtg ggtggtaagc
      961 tagagagagg agagacgccc caggaatgcg cggcgcgtga aatccttgaa gaaacagggc
     1021 tcaaagccaa gccagttcta aaaggtgtca tcacttttcc tgaatttaca ccagatttag
     1081 actggtacac ctatgttttt aaggtgacgg agtttgaggg cgacttgatt gactgcaatg
     1141 aggggacgct agaatgggtt ccctatgatg aggttttgag caagccgact tgggaaggtg
     1201 accacacctt tgttgagtgg cttttagagg ataaaccctt cttttcagcc aagtttgttt
     1261 atgatgggga taaattgttg gatacccaag ttgatttcta tgaataaagg agaaagcaga
     1321 tgctactaat caaaaatggt cgtgtaatgg atcccaagtc tggtttggat caagtttgtg
     1381 atgtcttagt tcaagatggg aaaattatca aaattgcgcc tgagatcacg gaagaaggag
     1441 cagaaacgat tgatgctact ggtcttgtgg ttgctcctgg tttggtcgat attcatgtgc
     1501 atttccgtga acctggtcaa acacataaag aagacattca tactggtgcc ctggcagccg
     1561 ctgcaggtgg ttttactact gtcgtcatga tggctaatac cagtccaacc atttcagacg
     1621 tggagacttt gcaagcagtt ctccagtcag ctgccaaaga gaagattaat gtcaagacag
     1681 ttgcgaccat tactaaaaac tttaatggta aaaacttgac tgactttaag gcgctcttag
     1741 aagctggtgc ggctggtttc tctgatgacg gtattccgct tgagagcagt aagattgtca
     1801 aggaagccat ggaggaagcc aaaaaattca atacctttat cagccttcat gaggaagatc
     1861 caggtttgaa cggtgttctt ggctttaatg aaaatattgc tagagaacat ttccatatct
     1921 gcggtgctac tggagtggct gagtacgcta tgatggcgcg tgatgtcatg attgcctatg
     1981 caactaaagc ccatgttcac atccagcatt tgtctaagga agaaagtgtt aaagtagtgg
     2041 agtttgctca ggggttaggt gcagaagtca cagcagaagt agcaccacag catttctcta
     2101 agacagaagc acttctttta acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt
     2161 tggaatcaga ccgtcgtgcc gttatcgaag gtctcaaatc aggtgtcatc acagttattg
     2221 cgactgacca cgcgcctcat catgtagatg aaaaaaatgt tgaagatatt accaaagcgc
     2281 catctggtat gactggctta gaaacatccc tgtctctcgg cttgacctat ttggtagaag
     2341 ctggtgagtt gagcttgatg gaattacttg aaaaaatgac atacaaccca gccaagcttt
     2401 acaactttaa agcaggttac ttggctgaga atggtccagc agatatcact atttttgatg
     2461 ccaaggctga ccgccttgtg gactcccatt ttgcttccaa agcagctaat tcaccattca
     2521 tcggtgaaac cttaaaaggg caggttaaat ataccatctg taagggacaa atcgtctatc
     2581 aagcttgata ggagttagaa tatgaattat tttcgaaaac gtagggagag acaagcgaaa
     2641 tctaatagtg gaatttactg tcccgcagct aatcgttcca aaattcaata tgaaactaaa
     2701 gaaaaagctg accatgcggt tcaatatgat aacggaggtt tagttagaag ctattattgt
     2761 cgtacatgtg cgtgttggca tactacttca aaatctaata aacctccgct aagtttgaaa
     2821 aactatggtc tgaaactctt tggtttagat aaatcagaat agaaagagaa gtatgtataa
     2881 gacaaagtgt ttacgagaga agttagtatt atttttaaaa attttcttcc caatcctgat
     2941 ctaccaattt gccaattatt ctgcctcttt tgttgatact gcaatgacag gtcaatacaa
     3001 cactatggac ttggctggtg tatctatggc aaccagtatc tggaatcctt tctttacatt
     3061 tctaacaggg attgtgtcag ccttggtgcc tatcattggt caccatcttg gtcgaggcaa
     3121 aaaggaagaa gttgcgtctg atttttacca atttatttat ttggccttgg gcctatctgt
     3181 ggtcttgctg gggatggtac ttttcttggc accaacaatc ttgaatcata ttgggttaga
     3241 agcagcagta gcggcagtag cggttcgcta tctttggttt ttatctatcg ggattatccc
     3301 cttgttgctc tttagcgtca ttcgttcctt actggattcg ctgggcttga ccaaactgtc
     3361 catgtacctc atgcttttgt tactccctct caatagcgga tttaactatc tcttgattta
     3421 cggtgccttt ggtgttccag aactgggagg ggctggtgct ggtttaggaa catccttggc
     3481 ctactgggtc ttgcttggga tttctgttct ggttttattt aaacaggaga agctcaaagc
     3541 cttacacctt gagaaacgaa ttccacttaa tatggataaa attaaggaag gagttcgttt
     3601 aggtctgcct attgggggaa ctgtcttcgc ggaagtggct atcttttcag tggttggctt
     3661 gattatggct aagttttcgt ccttgattat agctagtcac cagtcagcta tgaacttttc
     3721 aagtcttatg tacgcctttc ctatgagtat ctcatcggct atggctattg tcgtttccta
     3781 tgaagtggga gccaagcgat ttgatgatgc gaaaacctat attggtctag gaagatggac
     3841 tgccctcatt tttgcggcct tcaccttaac cttcctttac atttttaggg ggaatgtggc
     3901 cagtctttat ggtaacgacc caaaatttat tgatttgaca gcgcgttttt taacttatag
     3961 tcttttcttc cagttagcag atacctttgc ggcaccgctt cagggaattt tgcgggggta
     4021 taaggataca gttattcctt tttaccttgg tttgcttggt tattggggcg tagcaatccc
     4081 tgtggctacg ctatttgatt ccctaacaga ttttggagct tattcttact ggatcggctt
     4141 gattattagt ttgattgtga gtggggcgct ctaccgttgg cgtttaactg tgattatgaa
     4201 gagatttgaa tctttagcaa aatccaaacg ctaaaaagtt tgtgaaaaaa tattcttgat
     4261 aagaaaatcc cttgttttca cggggttttc ttttttattt tgtgaaattt cttttagaaa
     4321 aactttgaca gtatttgcca aaaacggtaa aatagtaagg taagaagaaa gttagaaagg
     4381 caagaagatg tcaactttag ataaaaatct tttgctagaa atgttccgta agatggaaga
     4441 aatccgtcgc atggacttaa aaattgcaca attagtaaag aaagggaaag tgccaggaat
     4501 gacgcacttt tctgttggtg aagaggcagc taacgtgggg gctatgttag ctctcaatcc
     4561 agatgatctg attacctcaa accaccgtgg acacgggcaa gctattgcta aagggattga
     4621 cctcaacgga atgatggctg aaatccttgg taaatacact ggaacctgta aagggaaagg
     4681 tggatctatg catatcgccg accttgatgc tgggaacctt ggtgccaatg gtatcgtagg
     4741 tggtggtatg gggatcgctg tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa
     4801 aatcgttgtc tgcttctttg gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt
     4861 gaacatggct tctatctgga acctgccagt cattttctat tgcattaaca acggttacgg
     4921 tatctctgcg gatatcaaga aaatgaccaa tgtagaacat atccatcaac gtagcgccgc
     4981 ttatggaatt cctggaatgt tcatcgaaga cggtaacaat gtcatcgatg tctatgaagg
     5041 atttcagaaa gctgtagacc atgttcgcag tggcaatggt ccagtcttga ttgaaagtgt
     5101 aacttatcgc tggcttggtc actcatcatc tgaccctggt aaatatcgta cgcgtgaaga
     5161 agtggaattg tggaaacaaa aagatccaat cgaaaacctc cgcaattacc ttattgaaaa
     5221 taacattgca agtgccgaag aattggaaga aatccaagcg caagtaaagg aagcagtaga
     5281 agcttctgtt aaatttgcag aggaaagccc attcccaccg cttgaatcag cctttgaaga
     5341 tatttacgca gactaaggag aaagagataa aatggaaaca aaaacaatgt ccttccgtga
     5401 caccattatc cttgctatgt ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg
     5461 agaagacgtc ggtgtcttcg gaggagactt cggtacttct gttggaatgc ttgaagaatt
     5521 tggtccagaa cgtgtccgtg actgtccgat ttctgaagct gccatctctg gagctgcagc
     5581 aggagcagcc atgacaggac ttcgtccaat cgtcgatatg accttcatgg acttctctgt
     5641 tattgccatg gacaatatcg tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa
     5701 aggtcaggtt ccaatgactg ttcgttgtgc agctggtaac ggagttggct ctgccgccca
     5761 gcactcacaa tctctagagt cttggtttac tcacattcca ggacttaagg ttgtggcacc
     5821 tggaacacct gcggacatga aaggcctgct taagtcttct atccgtgata acaacccagt
     5881 tattatactt gagtacaagt cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga
     5941 ctacacaatt ccacttgggg ttggtgaaat caaacgccaa ggaacggatg taacagttgt
     6001 tacttatgga aaaatgcttc gccgtgtggt tcaagctgct gaagaattag cagaagaagg
     6061 aatttcagtt gaaattgttg acccacgtac ccttgttccg cttgataagg atatcatcat
     6121 aaactcagtg aagaagactg gtaaggttat tctggtcaac gatgcccaca aaacaagtgg
     6181 ctatatcggt gaaatttcag ctattatttc agaatcagaa gcatttgact atctagatgc
     6241 accaatacgc cgttgtgcag gagaagatgt gccgatgcct tatgcacaaa acctagaaaa
     6301 tgcaatgatt ccaacagttg aaagtatcaa agatgcaatc cgaaaaactt ataacaaaga
     6361 ctagagttac ataatataag ttatgtaaat aaaataaagc tgacgagaaa ctttgtatct
     6421 tttaggtgca gagctcttcg tcattaatat cttagattag agcacgggct aaaagctcgg
     6481 aaaaaagata aatctccttg gcttcatcga agccatcgtc gatttcctat ttttcagtcg
     6541 cttttgacgc cctttgtatc ataaatagaa ttggagaggt catggttgat gacaagctaa
     6601 gagcgactcc tgcagctaga aagttagcgg atgatttagg gataaacctc tacgacgttt
     6661 ctggctcagg tgcaaacggt cgtgtccaca aagaagacgt ggaaacttat aaagacacaa
     6721 acgtggttcg catttcgcca cttgcaaaac gaattgccct cgaacataac attgcttggc
     6781 aggaaatcca aggaaccggt catcgtggta aaatcatgaa gaaggatgtt ttggccctgc
     6841 ttcctgaaaa tatcgaaaac gatagcatca aatctcctgc tcagattgaa aaagtggaag
     6901 aagtccctga taacgtaaca ccatatggtg aaatcgagcg tattccaatg acaccaatgc
     6961 gtaaggttat tgcccaacgc atggttgaat cttacttgac tgcgccaacc ttcaccctca
     7021 actatgaagt tgatatgact gaaatgttgg ctcttcgtaa gaaggttctt gagccaatca
     7081 tggaagcaac tgggaagaag actactgtaa cagaccttct ttcgcttgca gttgttaaga
     7141 ctcttatgaa acacccatac atcaatgctt cattgacaga agatggcaag actattatca
     7201 ctcacaacta tgtcaatctt gccatggcag ttgggatgga taatggattg atgacacctg
     7261 ttgtttacaa tgctgagaag atgagtcttt cagaactggt tgtagccttt aaggatgtta
     7321 ttggtcgtac cttggatggt aaattggctc caagtgagtt acaaaattca acattcacaa
     7381 tcagtaattt gggaatgttt ggtgttcagt cctttggccc gattattaac caacccaact
     7441 cagctatcct tggtgtcagt tcgacaatcg agaagccagt tgtcgtcaat ggtgaaattg
     7501 tgattcgccc aatcatgagt ttaggattaa ccattgacca ccgtgtcgta gatggtatgg
     7561 ctggtgctaa gtttatgaag gacttgaaag agttgattga aaccccaatc tcaatgttga
     7621 tttaagagca agagtattca tttttaagat atagataaag gaaggaagac atggccttag
     7681 aagtaattat gccaaaagcc ggcgtggata tgacagaagg acaaatcgtc caatggaata
     7741 aaaaagtcgg agaatttgta aaagaaggag aaatcctttt ggaaatcatg actgataaag
     7801 tcagcatgga attggaagcc gaagaagatg ggtacttgat tgccattctc aaaggagatg
     7861 gtgaaactgt ccctgtaacg gaagttatcg gttaccttgg tgaagaaagg gaaaacatcc
     7921 caacagctgg agcagcatcg ccagaagcta gccctgtacc tgtagcaagt acctcaaacg
     7981 atgatggtaa gagcgatgat gcttttgaca tcgttgtgat tggtggaggt cctgctggtt
     8041 atgttgcagc cattaaagct gcccaactcg gcggtaaggt tgcccttgtt gagaaatctg
     8101 aacttggtgg aacctgctta aaccgtggat gtattccaac caagacctac cttcatagcg
     8161 ctgaaattat tgaaaatatc ggtcatgctg caaatcgtgg tatcgtgatt gaaaatccta
     8221 acttcactgt tgatatggaa aaacttttag aaactaaatc taaagttgtt aatactcttg
     8281 ttggtggtgt tgcaggactt cttcgtagct acggagttgc tgttcataaa ggaattggta
     8341 caatcactaa agacaagaac gtcttggtaa atggttctga attgcttgaa accaagaaaa
     8401 tcattcttgc tggtggttca aaagtcagca agatcaacgt ccctggtatg gaatctccac
     8461 ttgtcatgac tagtgatgac attcttgaaa tgaacgaagt gccagaaagc cttgttatca
     8521 tcggtggtgg agttgtcggt atcgaactcg gtcaggcctt catgacattt ggttcaaaag
     8581 tgactgttat cgaaatgatg gaccgtatag ttccagctat ggatgtggaa gtttctaaga
     8641 accttcgctt gatccttgag cgtaaaggaa tgaccatctt gactggtact aaactgcaag
     8701 aaatcattga ggaaaatggt caacttcgta tcaaggttga aggaaaagac gatatcatcg
     8761 caagcaaagc tcttctttca attggtcgta tgccagacct tgaaggtatt ggagaggttg
     8821 agtttgaatt ggatcgtggt tgtatcaagg tcaacgaata catggaaact tcagttccag
     8881 gcatttatgc accaggtgac atcaacggta ctaagatgtt ggctcacgca gctttccgca
     8941 tgggtgaagt ttccgctgaa aatgccctta aaggaaatca tgcagttgcc aaattgaatt
     9001 tgactcctgc agccatctac actcttcctg aagtagcagc agtaggtttg acagaagaac
     9061 aagcccgtga gaaatacgat gttgccatcg gtaagtttaa ctttgctgct aacggtcgtg
     9121 ctattgcatc tgacgcagct caaggtttcg taaaagttat cgctgataag aaatacggag
     9181 aaatccttgg tgtacacatt attggtcctg cagccgcaga attaataaac gaagcatcaa
     9241 gcatcatcga aatggaaatc actgttgagg aaatgctgaa gaccatccac gggcacccaa
     9301 cttactctga agtgatgtac gaagcgtttg cagatgttct aggaatggcc atccattcac
     9361 ctaagaaaaa ataaaacgaa gatagattag actggaaggt tatttccagt ttctatcata
     9421 taaagtaaag ggatatcatg aaatacatta tcaatcattc aaatgacact gcttttaata
     9481 ttgccttgga agaatacgcc tttaaacacc ttttggatga ggatcaaatc ttcctacttt
     9541 ggattaacaa gccatctatc attgttggtc gtcaccagaa cactatcgaa gaaatcaacc
     9601 gtgattatgt tcgcgaaaat ggtattgagg tagttcgccg tattagtggt ggtggagctg
     9661 tttaccacga tttaaataac ctcaactaca cgatcatctc caaagaagat gaaaataagg
     9721 catttgactt caagagcttc tcaactccgg ttatcaatac cctggctcaa cttggggtta
     9781 aagctgagtt cacaggtcgt aatgaccttg agattgatgg taagaagttc tgtggcaatg
     9841 cccaagccta tatcaacggc cgtatcatgc accacggttg cttgctcttt gacgttgatt
     9901 tgtcagtcct cgcaaatgcc cttaaggttt caaaagataa atttgaatca aaaggtgtga
     9961 aatccgtccg tgcccgtgta accaatatta tcaatgaatt accaaaaaaa atcacagtcg
    10021 aaaaattccg tgatttactc ctggaataca tgaaaaaaga gtacccagag attactgaat
    10081 acgtcttttc agaagaagaa ttggccgaaa tcaatcacat caaggatact aagtttggaa
    10141 cttgggactg gaactatggt aaatcacctg aatttaacgt ccgtcgtgga accaaattca
    10201 ctagtggtaa ggttgaagtc tttgctaacg ttactgaatc aaaaatccaa gacatcaaga
    10261 tttatggtga cttctttggt attgaagacg ttgctgcagt agaagatgtc cttcgtgggg
    10321 tgaaatacga acgcgaagat gttcttaagg cgctaaaaac cattgatatc acacgctact
    10381 tcgctggtat tagccgtgaa gaaatcgctg aagcggtagt tggataaatc aaaaagaagt
    10441 tggccaacta accaacttct ttttttgata tttatttaca taatttaaaa tacgtaaaat
    10501 cataaactat ccagagcatt cttttgttca tcactaacaa tatgggtata gaggtcagtg
    10561 acttgtgtgc tagcatgtcc tagttggtga ctgactaaaa cttgtgattt agtcgcatca
    10621 tagagcctag ttgctagtgt atggcgcagt ttatggggtg ttacacgcac tttaaaatcc
    10681 tctgagtatt tagcaaccat tttctcaacg ctagaagcat cgatacgatt aggaacacct
    10741 ctgtagagag ttaaaaaaag ggctgtatct gttttttccg ttttatagcg ttgattccga
    10801 atggccagat aattctctaa ataaggttta gcaaaagcag cgacattgac tgagtcacgt
    10861 ttgccacctt ttcgagtaac atcaataacc atcattttta gattgagatc tcttagatct
    10921 agattaacag cttcagataa gcgaacacca gatgccaaga gaagggcaat aatggctaaa
    10981 tctcgttctt tatttttgtt gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc
    11041 tcttgatcga tataagttag aaaaccttct gtttcatcac ctagaaagag tttttgcttg
    11101 atatttttag ctctggcagc aagggtttct ttctttttct tggttgaaac ttttttcatt
    11161 acattacgat agaaataagg ttccccctga tcgttttcaa cctcctcggt tagatacttg
    11221 taaagactag aaagtgctga taaggttcga ttgatagttg tctgtgaaat accttgtttt
    11281 gttgtattag cattcagcaa gggacgttca cgtagataaa ggataaagga ttccatgtct
    11341 ttcttagaca tattttccaa aactgataaa ggaatatcgg atattttatc agcgtttgaa
    11401 ataccagact ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg
    11461 gttgtaaaac tgtagggcac agccagctta gattggtagt attccagaac ataccagggc
    11521 atgagttgtt ttagtttgtc gattcgttcc agtaaaatct cacgtttcat gtattttctc
    11581 cataagtaag tatactagta gtatagcata gacttgtata tttttcaaga aaattatagt
    11641 ttttcagaaa gatgttatag gagtttttca aagtgataaa aagacttaga cctacaaaca
    11701 aaacagaata aggaaaataa taaaaatctc acccactaaa cttctgttaa tactacatag
    11761 ctagaaattg atttgattgt cctgattgtt ttatcctatt tcta
//
LOCUS       DAVKXA010000056        11026 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKXA010000056 DAVKXA010000000
VERSION     DAVKXA010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.056"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1..982
                     /locus_tag="VW883_001797"
                     /pseudo
     CDS             1..982
                     /locus_tag="VW883_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1110..2132)
                     /gene="cbpF"
                     /locus_tag="VW883_001798"
     CDS             complement(1110..2132)
                     /gene="cbpF"
                     /locus_tag="VW883_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV0274889.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDSPLTYDEEKLKAAPWYYLDPTTGI
                     MQTGWQFLGNRWYYLHSSGAMATGWYQDGSTWYYLDAETGDMRTGWQYLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYTYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2151..2972)
                     /gene="cbpG"
                     /locus_tag="VW883_001799"
     CDS             complement(2151..2972)
                     /gene="cbpG"
                     /locus_tag="VW883_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0274890.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVCYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGYSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3053..3292)
                     /locus_tag="VW883_001800"
     CDS             complement(3053..3292)
                     /locus_tag="VW883_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274891.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3442..3708)
                     /locus_tag="VW883_001801"
                     /pseudo
     CDS             complement(3442..3708)
                     /locus_tag="VW883_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3733..4044)
                     /locus_tag="VW883_001802"
     CDS             complement(3733..4044)
                     /locus_tag="VW883_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0274892.1"
                     /translation="MDWDFADTCWEKDPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSLWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3969..4211)
                     /locus_tag="VW883_001803"
     CDS             complement(3969..4211)
                     /locus_tag="VW883_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0274893.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(4212..4844)
                     /locus_tag="VW883_001804"
     CDS             complement(4212..4844)
                     /locus_tag="VW883_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0274894.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(4858..5853)
                     /locus_tag="VW883_001805"
     CDS             complement(4858..5853)
                     /locus_tag="VW883_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0274895.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5850..6548)
                     /locus_tag="VW883_001806"
     CDS             complement(5850..6548)
                     /locus_tag="VW883_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0274896.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6626..7636)
                     /locus_tag="VW883_001807"
     CDS             complement(6626..7636)
                     /locus_tag="VW883_001807"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0274897.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SSQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7620..8627)
                     /locus_tag="VW883_001808"
     CDS             complement(7620..8627)
                     /locus_tag="VW883_001808"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0274898.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8614..9567)
                     /gene="mvaD"
                     /locus_tag="VW883_001809"
     CDS             complement(8614..9567)
                     /gene="mvaD"
                     /locus_tag="VW883_001809"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0274899.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(9549..10427)
                     /gene="mvk"
                     /locus_tag="VW883_001810"
     CDS             complement(9549..10427)
                     /gene="mvk"
                     /locus_tag="VW883_001810"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0274900.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10549..10728)
                     /locus_tag="VW883_001811"
     CDS             complement(10549..10728)
                     /locus_tag="VW883_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0274901.1"
                     /translation="MLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNT
                     TVDGYFVNYNGEWVQ"
BASE COUNT         3287 a         2531 c         1960 g         3248 t
ORIGIN      
        1 cgagacctga agagaggaca gaattagaac gtcttcaagc agaaaatgag tacctgagag
       61 cggagaatgc catcctaaaa aagttaagag aactccgatt gaaggaggaa aaagagaaag
      121 aagaaagaca gaaattgttc aagaattaat gactgagttt tcgttagatc ttcttctaaa
      181 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctag ataaaccaga
      241 taaggaccaa gagcttaaag ctgaaattca atccattttt atcgaacaca agggaaatta
      301 tgcttatcgt cgaattcatt tagaactaag aaatcgtggt tatctggtaa atcataaaag
      361 agttcaaggc ttgatgaaag tactcaattt acaagctaaa acgcgacaga aacgaaaata
      421 ttcttctcat aaaggagacg ttggcaagaa ggcagagaat ctcattcaag gccaatttga
      481 aggctctaaa acaatggaac agtgctacac agatgtgact gaatttgcca ttccagtaag
      541 tactcaaaag ctttacttat caccagtttt agatggcttt aatagcgaaa ttatcgccta
      601 taatctttca acttcaccca acttagaaca agtacaaaca atgttggaac aggcattcac
      661 agagaagcac tacgagaata cgattctcca tagtgaccaa ggctggcaat atcaacacga
      721 ttcttatcat cgattcctag agagtaaggg aattcaagca tctatgtcac gcaagggaaa
      781 cagccaagac aacggtatga tggaatcctt ctttgggatt ctgaaatcgg aaatgtttta
      841 cggttatgag aagtcgtttc agtcgtttaa gcaattggaa caagctatta tagactatat
      901 tgattactac aacaataaac gaattaaggt aaaactaaaa ggacttagtc ctgtgcagta
      961 cagaactaaa tcctttgaat aaattatttg tctaactttt tgggatcagt acattgttaa
     1021 cttgatacta tgcgtttttt gattgtgaag acttttatcc acctattata caaagtcaag
     1081 tatccatcac agtttacaat tagtcttcat tacttaaccc attcaccatt atagtttaaa
     1141 tagtaaccac ctactgtggt attaacagct aaagcacctg aatcataggt atagtaccag
     1201 ttaccattga cttggaacca gcctgttttc atatctccat tacttgcatt tagatagtac
     1261 caagtcgaac cttcctgata ccaaccagtt gccatagctc ctgatgaacg gagatagtac
     1321 cacttgttac caaggtattg ccagccagtt ctcatatcac cagtttcagc atctaaatag
     1381 taccaagttg aaccatcttg ataccagcca gttgccatag ctcctgacga atggaggtag
     1441 taccatctat tacctagaaa ttgccaacca gtttgcataa tgccagttgt tggatctaga
     1501 tagtaccatg gagctgcttt tagcttctct tcatcatacg taagagggga atccttaacc
     1561 caaccacgtg ctagctctcc aaccgtcaat ctgttgatgc gcgaatcaaa gccaccatcc
     1621 ttctgtaaat aataccaatg accctcttcg taaatccaac cagtttttaa agtatgataa
     1681 ctacgctgat cttcaaaata atagactcgt ttctctgctg ggctatcata ttcttcccca
     1741 tgatgtttgt tggtattcgt agcagttttt gcttctaaaa cttgcttgcc aacaaattct
     1801 tgtaagacac catcttgacc aaaataaaac caatctggtc taagagcaat ctctattctt
     1861 ggagaaggac caatcgtaac ccccttgtgt ggagcaggta tatattgcca gccgacaacc
     1921 atctctccgg ataaaggatc aaaataatag tacttcccat ctatcactct ccagtaggtt
     1981 tcttttagat cccccttttt gtagtaggtt ctaccatttt cttggacaaa ctgccatcct
     2041 tcagaatcat ctgcaaatac tgtactggtc cctagcaaac cgaagaaaaa tgtggctagt
     2101 gcgacttgca tcattttttt caaaagcttc attttatata tcctccaaca ttaaatccac
     2161 tcaccagatg aagcgaagtt ataaacttta ccatcgatag tttggctacc tgtaaccatt
     2221 gctccatttg aattgagata ataccatttt ccatttactt tttgccaatc tgtaagcatc
     2281 ttaccggaac tgtctaaata ataccaagta tcatttatct cctgccaacc cgtttgttta
     2341 tcatgttgtc tataatggta ccaactacca tttattttct tccatccttc aagagagtaa
     2401 cctttaagaa ccgaataaat aaatggcaaa tttcgttcat ttaatttaac tgcactgtta
     2461 atttgattag ctccatctcc taaagtatgc actcctacta cacggtgact agcatcataa
     2521 actgtagatc cactataccc ctctaaagta tcaacttggt aatccaagaa catgccatca
     2581 tcacttaaaa cttgtttttt atctgtatac atttgatgaa ttttaaaatt atatgatgga
     2641 tagcctgtga tagtcacagt tattcctgtc aaattttttt gactagtagg aagacccaaa
     2701 gtccctaatt ttgcaccaat gggctcttct agaattaata aagccaagtc atattccctt
     2761 gcatccttag aatttaaatt tctaaattcc ttcaaataac aaacttcctt tactttgatc
     2821 tttccaaata gttcttgact tggactaaca gccggaagaa cataaatatc atccgcttct
     2881 ttcccatagt catgtctgta gtagttgtga gccgctgtaa ttaacacatt atctttaata
     2941 aaattcgcac ttcccctccc ttctacattc attccatcgg ctactccata atacttagat
     3001 aaaaccatag ctgaagtcga atacggatac tgtaaagtat tatcaatttt aatcaaatca
     3061 tcattaccga taatacttct gattgctttt ggtagtatga accatacgtt ggtgaaatct
     3121 cagataatga agaatcatta gactctggac ctttttctag tgtctcactt acctcatatt
     3181 cttcacctgt actagaaata acactcaaag cagatactgt cgataactgg ctagccaata
     3241 aagtactcgc aataattgaa atacccaatt ttttataaac agttttcttc attatcgtat
     3301 cctcctaatg taattatagc gtactattct aaatttctca atctactata gaatcaagaa
     3361 atctaccacc ttctttaaat accctccatt atcacataaa caggtaaact tttcaattaa
     3421 tgactgcgct tttcaatcac gctagaggta cttgcttgct tctttgatac taagttcagc
     3481 cattctttcc ttgtttttct caataaagca tgttacccaa gtgggattcg ttttggagta
     3541 gtctcgcaga gtccagccaa tggctttatt gataaaaaat tctgtttggt tcaagttatg
     3601 aaggagaatc ttttccatta attgagtatt ggtcttctct tttcttaaca actggtggtc
     3661 aatagcgaca cgtctcagcc agatattatc tgataggctc cattttatac tcaatgaaaa
     3721 tcaaagagca aactaggaag ctagccgcag attgctcaaa acactgtttt gaggttgcag
     3781 atagagctga cgtggtttga agagattttc gaagagtatt aagattattt cttctagttc
     3841 agggtgttca tacaccaaac tccctactac tcgatctagg atatctaccg tgtcccacaa
     3901 ggattttgtc acgactaact gctctagctt aggcaaatcg gtttccttta gataagactg
     3961 cattgctttc aaatagttag cagccacata ttggtatttt ctaggatcct tttcccagca
     4021 agtgtctgca aaatcccaat cgataatctt tgtttttttc gcttctggaa aatattttta
     4081 tagagtttat ttctttcagg caccgcaata cctagaaaag aaaattgatg gcgcatatag
     4141 gcttccatgg accttgcttt tttagagtct tttgctgctt ctagctcctc aagtaaatct
     4201 gctaaactca tctaaaactc ctcttgcccc accaaatggt gctgaaaggc atagacagcc
     4261 gcctgggtac gatcgctgac ttcaagtttg gcaagaatat tggacacgtg ggtcttgacc
     4321 gtcttgagag agataaagag gtcatctgcg atgcgctgat tttcgtagcc cttggcgatg
     4381 agttggagaa catctcgctc acgcgcagtc aattcttcat gaagttccat atgattgcgg
     4441 tggtattcaa ccttcttgct aacctcttgc tcaatggcca gctcgccagc agctacctta
     4501 ctgacggcat gaagcaattc atctgcacta gaagtcttga gcatatagcc tttggcacca
     4561 gcatctaaga ctggcatgat tttttcattg tccaaataag aggtcacaat caaaatcttg
     4621 gcttcaggcc attctttaag gattgctaag gtcgcgtcaa ttccattcat ctcaggcatg
     4681 acaatatcca tgacaatgac atctggacgc agttccaagg ccaagtcaat cccttgagac
     4741 ccgttggacg cctcacccac aacttctaca tcgtcttgga ggtcaaagta gcttttcaaa
     4801 cccaaacgga ccatttcatg gtcatctact agtaaaattt tcatctttac tcctttatca
     4861 ttccttatct aacaggggaa tacggatatc aactgccagc ccttgcttgg gagctgttaa
     4921 taactgaacc gtccctgcca tatcttcaac ccgctccttg atatttcgca gtccataact
     4981 caagtcgtct aagctcccta actggaaacc aatcccattg tccaccacct tcagttgcaa
     5041 ttcaacatct gtctgataga ggtagacatc taggcaagat gcctgggcat ggcggagggt
     5101 attgctaatc aactcttgca ggatacggaa gatatgctcc tcgattttct taggcaattt
     5161 cgtcatattc tgcttgagac taaccctaag atcactcttg tcctcaagct cttttaagag
     5221 aatctgaatc ccttctatca agctcttctg ctccagttca actggtcgca aatgcaagag
     5281 caaaacccgc aaatccttct gggcagtttc taaaatagct gtgacactct gcaactggat
     5341 ctgcatcttt tctctatcca atttcaaagc ctgctgactg atacccgata aaatcatgtg
     5401 ggccgcaaac aactcctgac tgactgtatc gtgcaaatcc cgagcaattc gcttccgttc
     5461 cttctcgatg atttcctctt cctgagcaag gctctgattt tcagcttttt gaagagcctc
     5521 tgtcaaaagg ttaagtttac ctgataagga cttgaaactg gcatccaaat ctggatctgc
     5581 aacctgaacc acttcttgcc ctgctaataa acgcttgaga ttagcctgca tttttcttag
     5641 agaaagctct tcgatccctc gccaaaacag ggctaagaga caggtcatgg acatgctgaa
     5701 aaccaacaat aaaaagacaa atttttctgt tttttcgaca tcgtacaaaa agatagacca
     5761 gtcaaaatca agtatttcca gcaagctgtg ggagaaaaaa aagacaaata ggaaggaggt
     5821 gagagcaata atgacatagg cttgtttttt catcctctaa ccacctccac atcaccaatc
     5881 atagtggtca agaaaatctt gacactcttg ttactcttga gatagtcttt tgtttcttga
     5941 tgatagtgtt cattgcggag ggctcgcttg ggctggttga aaaaagtcaa atccccatag
     6001 agacagttaa cgctgagact gacttccaca tctacaggta cgatgatttt ggtcgttcct
     6061 accatctttc tgaggataat gacattgtca tgattggtta agatgaccct ctccagatga
     6121 atagtgtcct tgcccatgaa gcgaaagaga ttgatatcat cgaattggca agtctggtag
     6181 cttgaaaaat gatgaagatt tccaaaccaa cgatttttct ccttcttaac cgtcacgacc
     6241 tcttcaaaaa ccaaattggt ctgctctttt tcctggttca tcatcgggta aagaagaaag
     6301 aggctataga taaccgcaac aaaaatagct agaatcacaa aaggattgag cataacgatg
     6361 aaaaagaaga gaatggttac cgctactaaa agaagattat ttccctcttt accagtgtag
     6421 tagcgaatca aaagcaaaaa gaggaatagt atcagcagaa aacgcgaaaa atgctctgat
     6481 accatcaaaa tcagagctcc tgtcagaaga caggcttcga taaataaaaa gattttaaat
     6541 tttctcatag gttcatcctc tcccttctat tttatcacaa ttcaaaaaag tcacctcagt
     6601 ctgaggatgg aaaaaaaggc gctggttacg cctttttcat ctgatcattt gcttctttta
     6661 attttccata aagaagatag tctacttttt gtagatctgc tatggtggca cagttaaggg
     6721 aacacataat caagcgtaga tctgctttcc agccttggac aatgccaatc acttcttcaa
     6781 ctgtgtaggt ttcaaccaat tccagaacgg ttcgtgacaa tcccacagcc ttagcaccaa
     6841 aaaccaagca cttaatcata tccagcggat tccgaacccc tccactaacc aagagttcga
     6901 ccttatcttt ccattcttgg gcattgagaa gggcctgcat ggtagactga ccccattgat
     6961 tgaggtaatc acgctggcta ctacgacggt tttcgatata ggcaaagctg gtgccaccac
     7021 gacccgatag gtccactgta cgaacaccga attcataggc tctttcgatt gtcttggcat
     7081 ccattccaaa gcccacttcc ttgaggacaa taggaacggg aatttgcttg ctataatctg
     7141 ctagatgcga ttgccagctt ctaaacttcc tttctccctc gggcatgagt aattcctgca
     7201 tgacattgac atgcacttgc aatagcacag gattcatctc ttctacagtc tgaagtccta
     7261 actcgacagg cttgtccaat ccaatattgg ttccaaggag gagattggga tgactagact
     7321 tgacagaaaa agaatcatcc gttggatttt tgagggctgc gctataagaa cccgttacaa
     7381 ataaaatacc acaggattcc gccacctgag ccagcttttg attgatttct cttcccttat
     7441 tacttccacc agtcatggca ttgatataaa aaggaaagtc ccactttcga ccagcaaact
     7501 ctgtcgaaag atcgatttca tccagattgt aaagaggcaa ggaagaatga atcagctcca
     7561 cctcatcaaa gctattatag gaacttttct gctcaagggc atagaggata tgctcgtcct
     7621 tacgatttgt cgtcatgtcc tatcctttct tgatataaga gctcaatccc cagatcggcc
     7681 caacgatttt ttaaggtttt ggttgattgc gcatcaaaac tcagggcgat gccacagtca
     7741 ccaccaccag caccactact cttggcaacg gcctgcaaat cttgactggc ttctttcaac
     7801 tgtctaagca aaggcgtgta aatatctgta ctcaagcctt ctaaaagctt gctggctact
     7861 tctacttgct cgataacttt ttcggctttc ccctgctcca aggcttcgac caaagaaacc
     7921 accgtttctt ttgaggaact taaaaaattt tgattgatat tttgcttgat ttgctggacc
     7981 atgtgactcg atacagccac ttccttggtc catcccacta agaaatcaca ttctaaagtt
     8041 ggtttcactt gtgagataaa aaatccccaa tcacgctcca gaactgtcgc caagttttct
     8101 tcttctaacc aagcagccgc cttctggcga tcaaatgact ggtagagaac caaatcctct
     8161 gccacaatac aggcaaggtc gcccatggaa ccattgtctc ctcgcttgag caagacagcg
     8221 ctagtcagct tgaacaagag attctgatca accgaaagat tatagagagc caataaagcc
     8281 ttgacaacca agacaacgac gctgccacta gaacctagac caaacttttt cccttctcgt
     8341 tccattttgc cacagatttt tagggaaaaa ggtcttaaat tctgaccgcg aacagcgagg
     8401 aagtctccca tcaaagcaat cgtttcttga atcaagctgt agtcaggatt aggccttaag
     8461 tccactgcga aatcaaacat atctgaatag atacggtagc tgtcagaaaa agcaatctca
     8521 gccctcatat agatgggaat atcctttatc aaagctaact gccctggctc taaaatagca
     8581 tattcacctg cccaatagag ttttccgcaa gttttaacag caatcatctt gactcaaatc
     8641 ctttgttttt gacacaatca agcgataacg atgaccgaaa atttctgata aatgctccaa
     8701 gtctttctcc tgacagaaga ccttaacatt gggaccagca tccatggtaa agtagcaggc
     8761 ctctcctttc tcacgaagct ggcgaacaaa gtccatagcc tcataagagg catccgtcag
     8821 ataagaaaag gctggactag cagtctttgt cgtagcatgc atagccaggg catttttctc
     8881 cgttaattct ccaatcttgg caaaatcatt ttccttgaga taaatcagca tatcctgata
     8941 gtccttctca gactgacgaa cccagtcgtc aaaagtcgtc gaggtttcca cacaaagttt
     9001 catcccgtca cggctagaga ttggtttttt cttgtcctct agcaccaaca taatcatagc
     9061 tagtttcaag tctgtctcta cagggtaaat ttctccacta tccttatccc aggctcctag
     9121 tggtccataa aaactccgag aagaagaacc tgaggcaaat ttggcttcct gtgccaactg
     9181 acttctatcc aatccaagct tgaaataagc attacaagcc ttgaccaggg cggacaaacc
     9241 actagaactt gaggacaggc ccgctgccgt aggcatattg ttttgagtat cgatacggac
     9301 aaagccctca ccagctggac gataacggtc aataatctta ctcatcttgg catgctcgac
     9361 ctcattttgt agctgaccat tgatgtaaaa ttcgtcagct gttacattgg ctggtaaagg
     9421 cgacaaggtc gtctctgtat acatattttc caaagttaga gaaatactgc tagtagcagg
     9481 caccatctct ttttcttttt tctttcccca atatttgata atagcaatat ttgcgtagga
     9541 acgtactgtt acaggctctc tatccatgtc tgaacagctc ctttctcttc taatctttct
     9601 gctagttctt gtgcgtgtgt caaattggtt accaaggcta tgatacaacc tcctagccca
     9661 ccaccgctca tcttggcacc cagagcacca tggctaagag tcgtttcaac caaaaagtct
     9721 gcctcagggc tactgactcc aatttctttt aaatgtaaat gcgcttgact gaggatttgt
     9781 cccagtcctt cagcatcttt ttgtgaaatc gcaacttctg cttgctgggt taattctccc
     9841 aaggcatgca aaaacggtag ggcatccttg cccttatttt gaaccacttg gatggcttca
     9901 cgagtatgac cataaacacc cgtatcggca atcaccaaat aggcggataa atccatctca
     9961 agttctgtaa atcctacgtt cttgataaag cgaataggtt ggtcactaag acaggtctta
    10021 gcatccaaac cactaggatt catatgggca atcatttcag ctcgattgac caagatttct
    10081 agtacatcat gaggcagatc agcctgatag tagtcaaata ctgcacgaat ggccgctatg
    10141 ctgatagccg ctgacgaacc catcccccgt ttctcaggga tagccgagtc aatctcacaa
    10201 cgaatgcagg cttctgtgat attcaaatac tccagtgagg cataaaccgc catggacaag
    10261 gtatcctcct cataaaggcg ccaaggactc tctgcaggaa ctaccttaca ggtcacctcc
    10321 acctccaaaa gaggcaggga aatggcagga taaccgtaaa cgaccgcatg ttcccctatt
    10381 aaaattatct tactatgtgc ctgaccgaca ccaacttttt ttgtcatttt ttccttttac
    10441 tagacgaaaa aacgtcttat ttttcataca agtattaatt ctttcctatc tattttatta
    10501 tattttcaca aaaaaagcga ttgtttccat tcacaatcgc ttctttcatt attgaaccca
    10561 ttcgccatta taattgacaa aatagccatc tacggtcgta ttcactgcca aggcacctga
    10621 gctataagcg tagtaccatc tgccattgac ctggaaccaa cctgtcgtca tagaacgacg
    10681 aaagaaactc cataccatta agtaaagagg aaagtcgtga gggagcatgc gccattgaca
    10741 acctgtttta gtgacgtaca aagtctcatt aacaagtact cgtttcggtc atttataggt
    10801 gcggtgtttg gagaaatagg gttcaatctt agcccattct tgatcgttta aatcagtatc
    10861 atatactttg cgtgtcataa ctctagttta acattttttg tgaatacagg ttctaaataa
    10921 tcgaccacga aaatttctta agtggaaaac gccttatgaa gtatgctacg ggaaagttat
    10981 gcacttaatt tgacaattca agatgtaaaa atatatacta tagtag
//
LOCUS       DAVKXA010000057        10652 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKXA010000057 DAVKXA010000000
VERSION     DAVKXA010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.057"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(763..1962)
                     /gene="divIB"
                     /locus_tag="VW883_001812"
     CDS             complement(763..1962)
                     /gene="divIB"
                     /locus_tag="VW883_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0274902.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(1972..3030)
                     /locus_tag="VW883_001813"
     CDS             complement(1972..3030)
                     /locus_tag="VW883_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0274903.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(3034..4386)
                     /locus_tag="VW883_001814"
     CDS             complement(3034..4386)
                     /locus_tag="VW883_001814"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0274904.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(4490..5131)
                     /locus_tag="VW883_001815"
     CDS             complement(4490..5131)
                     /locus_tag="VW883_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274905.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(5133..7154)
                     /locus_tag="VW883_001816"
     CDS             complement(5133..7154)
                     /locus_tag="VW883_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0274906.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(7225..7524)
                     /locus_tag="VW883_001817"
                     /pseudo
     CDS             complement(7225..7524)
                     /locus_tag="VW883_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(8088..8480)
                     /locus_tag="VW883_001818"
     CDS             complement(8088..8480)
                     /locus_tag="VW883_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0274907.1"
                     /translation="MELDKFKTMMNVRKRMTYFLRFQRMAGSENQVRIDEEAWKLVLP
                     DQWHLSGEHEKAIREGLEIFAHDINSIENERARKYFIIHYCYMRKKTMSECVEMAGTS
                     STSYHRYKQISVLNFARIHQNGELEAYK"
     gene            complement(8517..8774)
                     /locus_tag="VW883_001819"
     CDS             complement(8517..8774)
                     /locus_tag="VW883_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274908.1"
                     /translation="MKKARLDSEILEELLEKNKVNYLDANQYAIEIGEILAKVLGAYL
                     SNINQEDVERRKQIGIESAEERKRKRDERIAKFGNPRRRLS"
     gene            complement(8783..10081)
                     /locus_tag="VW883_001820"
     CDS             complement(8783..10081)
                     /locus_tag="VW883_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000172765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274909.1"
                     /translation="MTLKGMGYLRKKLANYKMGVDTRYNQYAMQHNDIDVGITIPPQI
                     RQQYRAVLGWTAKGVDSLADRLVFREFANDEFGANEIFAQNNPDVFFDSAILSALIGS
                     CCFVYISQGDDDDAPRLQVIEASNATGVLDPITGLLIEGYAVLKRDDNGYAVLEAYFT
                     SDVTWFYPKDGKPFAIENPTGVPLLVPVIHRPDTVRPFGRSRITKAGMYYQRYAKRTL
                     MRSDVTAEFYSFPQKYVLGLSQDAEAIDTWKATVSSLLTFTKDDEGEKPNVGQFTTSS
                     MSPFTEQLRTAAAGFSGEMGLTLDDLGFVSDNPSSVEAIKASHENLRLAGRKAQRSLG
                     SGLLNVAYVATCLRDEFPYLRKQFNKTVVKWEPLFEADANMLTLIGDGVIKLNQAVPG
                     YMDAETIRDLTGIKGSDKPAPVVKEGADGGRYVSESTPEN"
     gene            complement(10279..10623)
                     /locus_tag="VW883_001821"
     CDS             complement(10279..10623)
                     /locus_tag="VW883_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274910.1"
                     /translation="MPLPTGKIDLNEYGKHLAEKSAEIYKEKTKQAVDAMERHRQECL
                     ARDAKWQAVIDRSDELLKEKKEREHQQEIERLMEEKRKEVDREVSQRLSMPNEHQKKL
                     NKAMSEMLKDLF"
BASE COUNT         3111 a         2414 c         1820 g         3307 t
ORIGIN      
        1 atattttaaa aatatttctt ccctactaac actaataagt ccgatatggt aaattcttga
       61 cctattagtt gctctaacca tttttttcct gtttcccaac taatacatgt ttcttactgg
      121 atggtatata taaatgatag tgtccctcat aaggagtagg taatatctta atcttatcaa
      181 caattctcat aacaaaccta acctttaata aataaaagag gggttaagta aaacatactc
      241 tagtccctca gtccgcaatc aataaaataa tgactaattc tattaatctc ttgctgcaag
      301 actaatacgg aaaatttaaa tgactgtcta aaatgaaatt gaaaaagctt gatgttagta
      361 aatgaacaaa cttcaacaac cagcaagagc aaggattgct aaaccaaatc cgatacctgt
      421 tgcaagtcca gctgaaaaat cactaactgg tactgaaatt tcctcaaata aaaagttatc
      481 ttgcatgatt atcactccct atctttttaa caacaggcta ctccaattaa gagaactacc
      541 ccagttccaa gtaaaacttc ccccaaaaat tcaccatctg taggggctac gatttcttca
      601 atttcttcaa ataagaatac ttcatctgac atatgtgtta ccttcttcat caaaaattat
      661 tttgtaatcg attacattgc agatgtaaca taaagaaaaa cagatgtcaa atattaaacg
      721 taaaaacatg gtcactaaag aactataaga gaaaaggtaa acctagcgac gcgatgaacg
      781 ctgggtcgtt tggtttcgat tgctctcttc ctcttgtttt ttctgttctt cttcttgttt
      841 tttctcagct tccttggcct cttgtttggc tttttcctca gcttccataa ttaatttatc
      901 cgccacagtg tagctgtaga ttccagcttc catgtcgacc acactcggtt ctgacaattg
      961 aggcttaatc ttactgtaat atggcagttt cttactcatt tcagatagag gaaccaagac
     1021 ttcgtccgaa tcattcatgg tcaatcgaat taaatcggat gtcaccttgc ttggggctaa
     1081 ttccaccttt tggatagccg ccttgagttc tgggctaatt tgagcaagtt ctgagacaaa
     1141 aaccttgatt tgttcactat cattaaagag aactgataaa taagtttctg gtaaactgtt
     1201 cagactcaca gaactagtct caagctgacc actggaaaga ataggataat gattttcacc
     1261 agaaatatag taggccacaa tatcatattc cttgacctta atagtgaact tagttggaaa
     1321 ttgatagaca agttgagctg attcaaccca atagttagac ttaatctgct tttcatattt
     1381 tgccttgtct agcagaaggt taatcgtata atccgaatcc tgaatgcctg aagcctgtcg
     1441 aatatcatca gctgtagttt gcaccgttcc ctcaacacga atatctttca tggtcgcata
     1501 aggactgagc aagtaggcag agacaatcaa taaaagcaga cttggaaata aaatcgtgaa
     1561 ggctcgcaag atatggatac caggaatctt tgctttggct ggtttttcct ttgtagcctt
     1621 tttagcaagc tttttatcct gttcctcctt ctctttagac tctggttctt ctttctcttc
     1681 tttctctttg tcagcctctg aggatgctac tttttcttca gactcttcct tagctgattc
     1741 tgaatcttcc tggtctgttt cactctcctg gtcctgtttg tcctctgact tctcagattc
     1801 ttctcccatc cgagcttgtc tttccttttc cttctcctca gctagagccg cttcttcttc
     1861 agccttcttt tttagatatt cttggtttcg tttctgccat tctgataact ctttcaattc
     1921 ttcgaggatt tctttgtcct catttttctt atcttttgac atttactttc cttatgataa
     1981 atcttttttc aacaattgat aaaaatctgc tagagatttc aattccttag aagctttcat
     2041 cttagcttgg taatcttcct tgtgacttag taagtgagaa agcttctctt ccaaactatc
     2101 caaggtcaaa tcgctttctt gaaggtcttc tgcatagcct ttttttacaa agtaagctgc
     2161 attttcaatc tggtcaccac gactagcttc acgaccaagc ggcacaatga catgcaattt
     2221 tgctatcgcc aagagctcaa aaatcgtatt ggcaccacct cgtgtcacaa caatatcagc
     2281 caattccaac aagggttgat agagatcggt cacatagtca acacgaaaaa gattttggct
     2341 caactcattc aggctagaat ctccagttag attgataata ttgtagcgct ctgttagttc
     2401 tttcttatgg tctgtcacca attggttaaa gacacgagca cctgcagaac cgccaacaaa
     2461 caatacagtc ggcaatttat gattaaagtg ggtttgaata tccaccaatt catctggttc
     2521 tggatttttt tgatctgaaa ccttggtcac tgctcccaca tgctcaacct tagacaaact
     2581 cgaagcttgc tcaaaggttg aatacatctt agtcgcaaat ttataggcga ttttattggc
     2641 caagcccata gacaggtcag attcgtgaat aaagacaggc actcctgaca cacgcgctgc
     2701 gataacaggc ggtactgaga caaagccccc ctttgaaaaa agggtctgtg gacgaagtcg
     2761 caacatgata aagagcgatt ggacgattcc ccagccaact ttgaagacgt ccagcatatt
     2821 ttgccaagag aaatagcgac gcaatttccc agtcgcaatg gagtggaaag tgacatccaa
     2881 acctgactta aggatttctt ggtgttcgat accacgcttg tccccgatat agtggacttc
     2941 ccaaccatct tcgatgaact tgggcattaa caaaagattg agggtaacgt gtccaaccgt
     3001 ccccccacct gtaaagacaa tttttttcat attttattct tttaactccg ctactgtgtc
     3061 gataaagagg tcgccacgta cttcaaagtt agcatacata tcccagctgg cattggcagg
     3121 actaagaaga accacatctc cttgagtcgc aagctcatag gccttgcggg tcgcatctgc
     3181 aatatctgtc gcctccacat aagcgacacc agccttgtct gctgcccgtt tgacacgttc
     3241 tgcagattga cccaggatga ccatcttctt gagtccagta atatctggca ccaattcgtc
     3301 aaactcattg ccacggtcca aaccacctgc aatcaagacg accttgctgt tgtcaaatcc
     3361 tgacaaggct ttttgagtag ccaagatatt agttgattta ctgtcgttat agaatttaac
     3421 acccttgatg tcatccacaa actggagacg gtgtttgaca ccaccgaagg ctgaaagagt
     3481 ttccttgatg gtttgattgt ccacaccacg aagcttggct acagcaatag tcgcaagggc
     3541 attttccaca ttgtggctac ctggaacacc gatttcattc gctgccatga ctacttcacc
     3601 acggaagtag agttgaccat cttccagata agctccatca accttttcaa gtgttgaaaa
     3661 tggtacaaca gtggcttctg tcttggaagc caagtctttt accaagtctt gattaaagtt
     3721 caagacaagg aaatcagctg ctgtcatctt gttctggata ttccacttgg ctgctacata
     3781 ttcctcaaat aatccatgat aatcgatatg agttggcatg aggttggtaa taaccgcaat
     3841 ctctggatgg aattcttgaa cacccatgag ttggaaagaa gaaagttcca taacaagcgt
     3901 gtccttatct gatgctattt gagcaacctg actggcagga tagccgatat tccctgataa
     3961 aagaccatgt tgcccagcag cagtcaaaac ttccccaatc atagtcgttg tggttgtctt
     4021 accgttcgat cctgtgatac caataatcgg tgcttctgaa atcaaataag ccaattccac
     4081 ctcagtcaag actggaattc ccttggccaa agccttttca atcatgggat tgctgtaggg
     4141 gatacctgga ttttttacca tgagggcaaa ctcttcatcc aagagttcca aaggatggcc
     4201 acctgtaatg accttgatcc cttcttccag caaacattgg gcagctggat tgtcctcgaa
     4261 tggtttccca tcatttactg tcacaatggc acctaacttg tccaacaaac gagccgcaga
     4321 ttcaccagac ttggccaaac ctaaaacaag aactttctta tttttaaatt gatctattac
     4381 tttcatgtct cgaactccat ttctactcct actattttac catttttatg gaaataaaaa
     4441 agccacaaag tgtgtttgtg actctttctt ctaactgaat cttaccatat catctatgtg
     4501 ataaatcggt aactcgaatg acctgatcca cttgctccca aatcagagga ttgtgggtcg
     4561 caataataat ggtccgattc ggatttttta aagattctag gatggaaagt aattcctcag
     4621 aatttttggg gtctaaggaa gcggttggtt catctgcaag aatcaaaggc ggatccttta
     4681 aaattatctt cgctagtgca acacgttgtg cttctcctcc tgataactca aatataggtt
     4741 gcttcaaatc caaataagag aggtttacac agtttagagc ttgtttcatc aaagagattt
     4801 tctctttttc cttcaacttt ttaccaacta aacccagatt gagattctct ttgacggttt
     4861 ggctttcaat taagccaaaa tcttgaaata agtatcccaa gtaatctcta aagaaaacag
     4921 aaggcttgat gtccttaaga gaagtgccat catagatgat ttgccctttg tcatatggct
     4981 ccaatcgtcc aatcatattc aagagtgttg tcttaccaca gccacttgta ccgattaagg
     5041 cataaatttt cccaccttca aaatgaagat tcgtatctga aaatagctga cggcttccaa
     5101 attttttaga tatattcttt agttcaatca tcctattttc ctttcataat tgtcatagaa
     5161 acacgagatt ctttctgcgc ttgacggtaa agcgtcaaaa ctgcactagc tagaaagacc
     5221 aataaagtga gcaagccaat caccaagtct cgactgctta aaataaagag actagcacca
     5281 aatacaaaac tggcaaattg gctaaccata tactgagcat gtgtttcaaa aaatcgtaaa
     5341 cctgaaattc gtttaatcaa gatatctcgg cggaattgct cgaaatatag aagattgaca
     5401 gaataaaata gtaacaagga actagctatc cccacaatag ctcctaagat taaagttgct
     5461 gtttcagttt gaacttcatt ataacgagtt agataaacac ttcttccttc tttaagatag
     5521 gatacttgct cataaattcc agctttcttc aagagttcta gcccactctc atatcctttg
     5581 ataaagagtt gttttccagc attgatagac caactagata aggatataaa actatcacct
     5641 gtagaagtcg gcgtgaatac cactaaaatc ggatcagtca aatactgagt agatacggga
     5701 ttctcaccgt tattataaac aaaccgcttt tctcccattg aaagataact aacgtgcgct
     5761 ttcatctcat aatccaaagg agcacttgcc tcctcaccag attttccata ataactcaat
     5821 ctttcttcaa aaactttctt aagttctgct tctcgagagc gcaaatgttc tgggagcaag
     5881 aggataaact cacctttttg gagatgggct aacttctgtt tggtctcagc atctaccacg
     5941 accttttcct tgtccaaata actgggacta acatagagcg tattagcatc tggactatag
     6001 gtatccagtg tctctccctg ttcatttttt ccttgtggat tggcaaaatg gagcagatta
     6061 tcctttacat aaagagcttg ttcttcttcg attgcttcct tggcaaaggc ataccacttg
     6121 ctctgatttt ctgtatcttt tcctctatca cctaagccaa aggaaatctg gtaatagtct
     6181 gctctgtcct gccatgcttg ttttgaaatt tcaagttctt tcaatcgttg gtaagacgtc
     6241 aaacctgtct taacagcgta gcctactgta aaaacagcta ctaactgaca caatagggtt
     6301 aaagccatca agcgtttaag gggtaatctt cccttaataa cgggaactaa tgctttgtaa
     6361 ctcaaactca ttagataaag aagcattagt aaaattgaaa tcgccaataa aaacaacaga
     6421 tagaaactaa tcccaaaacc ataggtggct aacaagatag gataaaacaa accttgacta
     6481 aaaagaacga ctcccccacc taggaaggaa aggagggctg atagaaggag ccacttgata
     6541 tcagtcgata aagaatgccc catgatggat aagagagtct gaccagaaaa gagttttata
     6601 cctgcagctc tcatttcctt aatccgagtg ataatcacta aagcaaagaa agataagcca
     6661 aatattgcta aactaattaa aataagggga tttagtaata ttcgaaaagc aagaaaatag
     6721 ggcggtatct ttcggtcagc acttgcttta taacccaaat ctcctaattt atcggcaagc
     6781 ttttctttcg tcaaggagcc tgacaaaagg agataactat ttagcggatc actacgttca
     6841 cgactttctt ggctagcttc ttggaattct tttggtaaag ttccctgacc ataagttgca
     6901 taagtaaagt gagtcgtccc atccttactc ggctctacaa ttcttctagc tattaaactc
     6961 tgttctgagt ttgcaaaatt ctccaattcc tgttcaaata cctcacgcgt cggttcctga
     7021 gtatcttttt tgacacgaag taaagaaacg gaatcatagc ttgcatataa atattgtggc
     7081 gcacgtaaga caataatcca agcaaggaag aagctgagaa aaaaagttga taataatatg
     7141 aatagtttct tcatagtaga ctccttgtaa acaaaattcc ccctgtaatt tcttacaagg
     7201 ggaacgattt aaatcaatga acgattagtc ataatcacag taaaatgcta cttgttctcc
     7261 ccatttagtc caaatccatg cataggaggt ttttccagca ggagcttctc ctttatcaga
     7321 atgaccatcc catctgctca cgatggatga ataatgatat tttttaccat gatagtaatt
     7381 tgaaaaagcc taaccacctc ctgaaccttc tccatatgtc catactcctc catctggata
     7441 ttgtacagca gctgatgcag ctcccaataa tgtaaaattt gaaataagag ctagagcaag
     7501 taatctatgt tttttcgttt tcattttatt ttttctttca aaaaaagcac accttgagca
     7561 acaatgcaac aaaataaatc ctcctctctc ttttattaaa agcgctttct tatgtgataa
     7621 gaataacttt tttattattt gttgtcaagg aaaaaatcga attttttaga tgttttacta
     7681 tattatctct atgaataata ttatatagta gttttatttc aaaataattt gacttaggca
     7741 tcatttcaca cctcaatata gcgcctaaac ccttgatatt actgactttt tgaaaaatat
     7801 catttgatta gaaatcatta aaaattctca aaaagtccac aaaaaaaaag ccccacaaaa
     7861 gggcaataaa tgacgagttc agcaggcaag aaactagcac ggtcaaacgt gcttttttat
     7921 tgctgattgc tgataggtat attataccat gaagcgcgta gtttataaga ttatgacctc
     7981 acaaaagccc cccagattcg tttctaaggg cttctagttt atctatggtg ttttagttgt
     8041 ccagtacgaa acaaagcgaa ataagggggc gaatatgcag cctcagccta cttatatgct
     8101 tctagctctc cgttctggtg gattcttgca aagtttaaga cggatatctg tttgtatcgg
     8161 tggtagctag tggagctagt acctgccatt tctacgcatt cgctcatagt tttctttctc
     8221 atatagcaat aatggataat gaagtatttt ctggctctct cgttctctat gctgttgatg
     8281 tcgtgggcga atatctccaa cccctcacgg attgcttttt catgctcacc gctcaaatgc
     8341 cactgatcag gtaagacaag tttccaagcc tcttcatcta tcctaacttg gttttcacta
     8401 cctgccatcc tctgaaatct cagaaagtaa gtcatccgct ttctgacgtt catcatcgtt
     8461 ttaaacttat ccagctccat ttttaacgac aacctttcta ctcctgtaac ttatgcctag
     8521 cttaatcttc ttctaggatt tccaaacttg gcaatccttt catctcgttt tcttttacgt
     8581 tcttcagcag actctatacc tatctgtttt cgacgctcca catcttcttg attgatatta
     8641 ctcaagtaag ctcctaagac ctttgcgagt atttcaccaa tttctatagc atattgattg
     8701 gcgtccagat aattaacttt attcttttct agtaactctt ccagaatctc actatcaagc
     8761 ctagcttttt tcaaattcgt ccttaatttt ctggagtaga ctcggaaaca tatcttccac
     8821 catctgcacc ctccttcact actggagcag gcttgtctga ccccttaatt ccagtcaagt
     8881 cacggatggt ttcagcatcc atatagccag gcaccgcttg attcagtttg ataacaccat
     8941 caccaatcaa ggtcagcatg ttagcgtccg cctcaaataa aggctcccac ttcacgaccg
     9001 ttttattgaa ctgtttcctc aaataaggaa actcatcacg taaacaagta gcgacataag
     9061 ccacattcag cagaccagaa cccagagagc gctgagcctt ccgaccagct aaacgcaagt
     9121 tctcatgact agccttgatg gcttcaacgg atgacggatt gtcagaaaca aaaccaagat
     9181 catccaaggt caatcccatt tccccagaaa atccagctgc tgcagtccgt aactgctcag
     9241 taaaaggaga catgctggac gtggtgaatt gtcccacatt cggcttttcc ccctcatcat
     9301 ctttcgtaaa cgtcagcaag ctagatacag ttgctttcca agtatcaatc gcctcagcat
     9361 cttgactcaa tcccaacaca tacttctgag ggaatgaata gaactcagca gtaacatctg
     9421 accgcataag cgttcgttta gcatatctct gatagtacat cccagcctta gtaattcgtg
     9481 accgaccaaa cggccgaaca gtatcaggcc tatgaatgac tggcaccagc aaaggaacac
     9541 ccgtcggatt ttcgattgca aacggcttac catctttcgg atagaaccaa gtcacatcac
     9601 tagtaaaata agcctcaagc acggcataac cattgtcatc ccttttcaaa acggcatagc
     9661 cctctatcaa caagccagtg ataggatcca gaacaccagt tgcattactc gcctcgataa
     9721 cctgcaaccg aggagcgtca tcatcgtccc cttgcgagat gtaaacaaaa caacacgacc
     9781 caatcagagc cgaaagaatc gcgctatcaa agaatacatc tggattgttc tgagcaaaga
     9841 tttcattcgc tccaaactca tcattggcaa actcacgaaa gaccaaacga tctgcaagac
     9901 tgtcaacacc cttagcagtc caacctaaga ccgctcgata ttgttgcctg atttgaggtg
     9961 gtatcgtaat accaacatct atgtcattgt gttgcatagc atactgattg tatctagtat
    10021 ctacacccat tttataattg gctagcttct tcctgagata gcccatacct ttcaatgtca
    10081 ttttatacaa ctacctttca tttcccgcga gaaaaaatgt acagtgatgg tgggaagttc
    10141 gggagctccg agggggaggg gggtatcccc cctccttctc ccttgcttct ccaatctctt
    10201 tcacaaaaaa tatttttccg attcacttta ttaaaaaact ttttaattat ttttttatgg
    10261 agtcttttta tgttctcttt aaaataaatc tttcaacatt tcactcatcg ctttgttcag
    10321 ttttttctgg tgttcatttg gcattgatag gcgctgacta acttctctat caacctcttt
    10381 gcgcttctct tccatcaagc gttcaatctc ttgctggtgc tctctttcct tcttttcttt
    10441 taatagttca tcggaacgat ctatgacagc ttgccacttg gcgtctcttg ctaaacattc
    10501 ttgtctatgt cgctccatcg cgtcaactgc ttgtttagtt ttctctttgt aaatctcagc
    10561 tgacttttct gctaaatgct tcccgtattc gtttaaatca atcttaccag taggtagggg
    10621 cattctatat acctcatctt tctatttgtt ag
//
LOCUS       DAVKXA010000058        10583 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKXA010000058 DAVKXA010000000
VERSION     DAVKXA010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.058"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(73..1497)
                     /locus_tag="VW883_001822"
     CDS             complement(73..1497)
                     /locus_tag="VW883_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0274911.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFAIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2040..4319)
                     /gene="pulA"
                     /locus_tag="VW883_001823"
     CDS             complement(2040..4319)
                     /gene="pulA"
                     /locus_tag="VW883_001823"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0274912.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4431..6389)
                     /gene="ligA"
                     /locus_tag="VW883_001824"
     CDS             complement(4431..6389)
                     /gene="ligA"
                     /locus_tag="VW883_001824"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0274913.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6482..7660)
                     /locus_tag="VW883_001825"
     CDS             complement(6482..7660)
                     /locus_tag="VW883_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0274914.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7740..8603)
                     /locus_tag="VW883_001826"
     CDS             complement(7740..8603)
                     /locus_tag="VW883_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0274915.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8606..10507)
                     /locus_tag="VW883_001827"
     CDS             complement(8606..10507)
                     /locus_tag="VW883_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0274916.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKSANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3173 a         2352 c         1894 g         3164 t
ORIGIN      
        1 cgtatttttt ctataattat tattttatag caaaaaaata aaaccaggaa aacaatttcc
       61 tgattttaca cgttatttca catcaaaaac aatggatttg acatttgtca tcgcttcaat
      121 gctatattta attccttgca ctccagctcc agaacctttg acaccaagga atgggaaatt
      181 atctggacca cgctgggttt tattattaat gtggactgta cctacttcaa gtttttcagc
      241 aattgcaaag gcttttttga aatcatttgt aaaaactgat gattgaaggc cgaattcaga
      301 ttcgttggca aaagcaatag cctcctctac actagccaca cgaatgattg gtaaaacagg
      361 accaaatggc tcttcccatg ccactttcat atcttttgta acttggtcaa aaagcactgg
      421 ccagaggaga ttgccctcac gtttgattgg tgtaagagcc tgagcctctt tttcttgtgc
      481 atcctcaatc aagccccaaa tgaagtcggc tgaagcattg tcaataacag gtgtaatatc
      541 agcattgtca aatggatcac caactgttaa tttagaaact tcttcctgaa gcaaagtagc
      601 taatttatct gctacacttt cgagaacaat gacacgttta atagccgtgc aacgttgtcc
      661 tgagtagcta aaggctcccg caacaatttg cttggcagca tgttccaaat ctgcatcttc
      721 tagtacaaga gctgcatctt tcccaccaag ttccaacatg ataggacgca taccagctaa
      781 acgaccaata cgttctccaa taggagttga acctgtaaag ttgatgaagt tgacttcttt
      841 gtgctcaatg atataatccc caatttctga accacgacct gtaatggtgt tgaaaacacc
      901 tgccggaatc cctgcttctt caaatgcttt agccaacaag agtccagaaa tggaaccttg
      961 tgttggtggc ttaaacatga ccacattccc tgcaatcaag gcaggtgcaa ttttagaagc
     1021 agataaatta actggataat taaagggagc aatcgctagc acgataccaa ctggttcacg
     1081 acggacaaca gccagtttgt ttttacttgc tgcctcaaaa ccaccacctt ccattgcttg
     1141 tccagtgata cggagacctt cctcagcagc ataacgaatc aagtctgctg tacgcactac
     1201 ttctccaatt gctgctttaa tcccttttgc tacttctttg gcaaggatag taccaatttc
     1261 ttccttatcg cgttctaaaa tagctgctgt tttatgcaaa taagccgcac gttcaattgc
     1321 tgataaagct cgccatgctg gcagggctgc acgcgcagct tgcatagcct catcagcttc
     1381 agtctgagtc atggctggaa ctgtacccaa ttcttcttga ttgattggtg aataaatcgt
     1441 aatttcttgt tcagatgatt tccattttcc atttactaaa ttctgatatc ttgtcaaatt
     1501 cttgtcctcc tgaaaatgat taagatatat tttaccaaat tttcagaaaa ccacaaccct
     1561 ttttgcgaaa tttttgagat tattttcaca agcttgattt ttcaaagtat actcaataaa
     1621 aataaaaaaa tccactacgt caaggcgagg ctaatgtggt ttgaagaaat tttcgaagag
     1681 cgtgaatgag tatcatctat agtaaaataa aaaactgaac aatttggttt gggacagtca
     1741 aaccaatttc tcacaatgtt ttagaaacaa gggtgtgcta ttccaatttc aggctactat
     1801 aactgtcata gattgctgaa acaaagtcta ggtaaaagtc ttcataataa aaagacctcc
     1861 tatcaaatgt tcaaaaactt tgataggagg tcttttttcg tgaaaatatt tatcaaattt
     1921 tctatacaag tgagctgtta gccaggttct ttctattctt tcaatttcaa tgaatggatt
     1981 ttttaccaat actcataact gggaattttt ctgtctaaaa atagcgagat agatggtatt
     2041 tataaaacac tcaagacagc tagactaata tcatttaaaa cattatcttc ttttgagcga
     2101 ctgttggtta ccaacatagc taaatttcct gcattttcaa attgataggg ttctgattta
     2161 gcattcacaa ctaccaagag gtgttctttg ccgtgaactt catagataag gcagccgcta
     2221 tgttcaatcg cagaatgcac aaagacatga tggtaaattt catcatagct agagtaagaa
     2281 aaggcaccag tttttgtctt caatcggatg acttgacgga taaactcaat actgtcttga
     2341 cgctcattaa tcaagttcca gttcacttgg ttcacactgt caggagcatt atagctattc
     2401 atcgcacgct ctctatcatc atgggtcaac tcaccatttt caccagtcgc aaccagtttg
     2461 gtacgaccaa attcttgacc gatttccata aaggccatcc cctgcatgag cagattcatg
     2521 gctgtggcag tttcgacctt gcgcatgatt tgctctgaac tttggtctgg atgaagggtt
     2581 gccaataaat cgtgaagatt gtaattgtca tgggcttcta catagttaag cacctgattt
     2641 ggatgtgtat agcttcctaa ttcacgactc cctaggattg ctttagctag aattggctct
     2701 gtcgcagcac cactgacaaa acctgacttg atagcaccat aaacttctcc ccctttgaca
     2761 gcatcgcgct gattgtcatt aaagaaacca atatttggca tctggtaggc attgtccttc
     2821 ttggccttat cataaggggc aagacctgtt cccatatccc atccttctcc atagaggata
     2881 atgttggagt cgatttcatc caagctttga cgaatcatct gcatggtctt gacatcatga
     2941 atccccatca agtcaaaacg gaagccgtca atattatatt cctgcaccca gtatagaaga
     3001 gaatcaatca tatacttgcg aaacatttcg tgttcactgg ctgtttcatt tccaacaccc
     3061 gttccattct ggaaggtacc atctggattc atacgataat agtaatcagg gactgttgtt
     3121 tggaatggtg catcaacaac tgagaaggta tggttataga ctacatccat aatgactcca
     3181 atacccgcat cgtgataagc ttgaaccatc accttcaaat cacgaatgac ctgagctgga
     3241 tcatctggat tagttgaaaa actagtttct ggcgcgttat agttttgtgg atcataaccc
     3301 cagttgtagg ttacatttcc atcctcatcg tattctttat gacggtctgc aattggttgc
     3361 aattgaacat aattgtagcc cagcttcttg atgtaatcaa aagcagttga ctggccgtat
     3421 tggttaactg ttccagcctg agcagcaccc aagaaagttc ctcgaagatg ttcatctaca
     3481 cccgatgtag gtgatttagt caaatcacga atatgcattt cacagataac tgccttacat
     3541 ggattttcca agcgccaagt agcctccgaa ccgtgcttaa cctcgaagtt ttcaacttgc
     3601 ttttctacat ggctcagaat agctgaacgt ttgccatcag ggctggtcgc gattgtataa
     3661 ggatcacgtg tcagtgtttg gtgatgaggg aattggactt gatactgata agccttacct
     3721 accaaatctt cctcaacatc caaactccag acaccgattg tattgtcctt atgattataa
     3781 gagtagctat tgcctctttt catctcaaaa gtcttccaaa cgggtgcatc attagcagct
     3841 gattcataaa cgacaacttg cacttctgtc gctgtaggtg accagaggga aaaatgagcc
     3901 tgattgtcct ctacacggca acccaattct ccttggtaac cccaatgatg atcaaaacta
     3961 gcactgttaa tggccttatc aaaggcaaaa ggattttgat ttttatagaa aggactggca
     4021 atagcaggat tttcagagta ataaatccta tcatcgcctt ccaaaatcca gacctctgtt
     4081 aataggggat agtgattaaa acggatagaa tattctttac tagtttgacc tgtatgaacc
     4141 acaaaattca agctttctat aacatgtgaa cttgggtgtt caaagctaaa taaagctcca
     4201 aaataatctt ctttgtaggt tagcaaatca attcgttgat cctgactttt tacaaaggag
     4261 caagtgtcat attctccatt cttacgatgg taatgaatgc gcatagggta gttatacatt
     4321 ttttattttt cctttttact ttgtttctat ttcactaata aatttttgtc aatctcgtct
     4381 caattaacag acatagtcat attctctaaa ctctgttttt aaacgatcca ttacaaactt
     4441 tctagccatg cctcatctct gacctggata ccaagttctt gtgctttttg cagtttactt
     4501 ccagcgtctg cacctaccac gacgaggtcg gtctttttag aaacactacc tgtcactttg
     4561 gcacccagac tttcgagttt acttttagct tctgagcgct tgagtcgttc caattttcct
     4621 gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta ctaccgtctg tcctttatag
     4681 tccagattga ccccagtttc tttcaattct ctgagcagaa tttcagagcc ttctgtcgca
     4741 aaataagtct gaagactttt ggcaatcacg ccacctagac tttcaatact agccacttcc
     4801 tctgaatctg cctgagacag attttcaatt gaatggaaat attgaagtaa aagctgacta
     4861 gccttgcttc cgacatgacg aattcccaaa ccaaataaga gcttctcggc agaattttcc
     4921 tttgatgctt ggatagcctg atacagttta gcagcggact tttccttaac cccctctaaa
     4981 aggaggaaat cctcttcttg caaacgataa atatccgcca catccttgac taaattagca
     5041 gcaaaaagct tctcaacaat agatggacca aggcctgtaa tattcatagc atcacgagaa
     5101 gcaaagtgaa tcaagccttc catgatttga gcagggcaac gcggattgat acaacgtagg
     5161 gccacttcat cttcaaagtg caacaagtca gagttacaac ttggacagtt tgtagggata
     5221 tctagttttt cttcagaaac ccgtttggac tctaccacac gtaaaacggc agggatgatg
     5281 tcaccagcct tatatacaat gaccgtatcg tcttttcgga tatctttttc agcaatataa
     5341 tctacattgt gcagggtcgc acggctaaca gtcgtaccgg caagttgtac tggtgttaga
     5401 ttagcagttg gagttacaac accggtacgg ccaactgtcc agtcaactga taagagttga
     5461 gcttcttttt cttcagcagg gaacttgtag gctactgccc actttggagc cttaacggta
     5521 aaaccaagtt cttcttgact tgctaggtcg ttgaccttga ttaccactcc atcaatatcg
     5581 taaggtagat tttcccgttc ctgtcctact tcttggataa aattccagat ttcatctatg
     5641 ttttcagcca agattcgctt aggattgacc acaaaaccta gttgttctag gtacttcaaa
     5701 cccttttctt ggctatcacg agttgaaggg ctggcttctt gatagagaaa cgttgcaaga
     5761 ttacgcttgg caactactgc tgtatccaac tgacgcagag ttcctgctgc cgcattacga
     5821 ggattagcaa attcaggctc tccattttct tggcgcactt ggttaacttg gtcaaaggaa
     5881 gcgcgtggca tgtaacattc cccacgaact gtgatatcta gttcttctgg caaagtcaaa
     5941 gggatgtcct taacacgctt gaggttttct gtgatatttt caccaattga accatctcca
     6001 cgtgttaccc cagcaaccaa aatccccttt tcataagtca gcgagataga taagccatcg
     6061 attttcagct cacaaatata ggtcggatga gccacttcct tacgaacacg cgcatcaaaa
     6121 gcatctagct cctcacgtga aaaagcatcc tgcaaactat aaagaggata ctgatgactg
     6181 tatttttcaa aaccatctaa aaccttgcca ccaacacgat gagtcggact gtctgctagc
     6241 acttgctctg gataagcagt ttctaactcg accaactcac ggtaaaggcg gtcatactca
     6301 ctgtctgaaa ccgagggatt atcgctggta tagtactcag tcgcatagcg attgagcaaa
     6361 gcgactaact cattcattct tttattcata agaccatttt accataaaac aagccctcct
     6421 cacaaacgag aagggcggaa aaaacactta gtttgaaatt atttttgaaa ctcaagcaac
     6481 cttatatcaa tttttcaaaa tgagttcgaa cataaataaa cgatatacaa gacaagatga
     6541 taacaccact tccaattatc aggaaagaag agagatgtac acttggcaag actgtcataa
     6601 atccttttgc aataggcata aatagaatag ctaaggtaaa aattgtactc agtactcttc
     6661 caagaaattc gctctcaacc ttggtttgta cttgagtaaa aaagtgaata ttaaaaatcg
     6721 tcataaacaa ttcacaaact aaatttccag aaaaggaaag aaaagttgga agtggtaatc
     6781 ccatcataaa aactccgaca cctgtcaaag ccagtaaaat caaaagatta taaatattag
     6841 ctttaatttt actagctaga agagccccaa tgatggaacc aatagccccc atagttaaaa
     6901 tacttgcata ggctccttct gacccgtaaa gctgattcga aaagggaagt agaaattcaa
     6961 aagctgcaaa aaagaaatta acgctggaag ctaccagcaa aaggaagaaa atttcttgct
     7021 gatgccagat atagtgtaac ccatccttga tatctacaaa aatatctctc ccagtaaaag
     7081 cctttttctc ttgaactttt gcttcctctt ttggaaggaa agccactaga acaaaagcaa
     7141 tgaaaaaagt cagcgagtct agcagtagcg tcatatggag acttgcaaac tgtaaaacaa
     7201 ggaaggaaag aacaggagag ctaacaccta caacctgcaa aaccagctct aagcgagaat
     7261 tatagatcac aatctcatct ttctccacca cttcagttat gatagcttta ttggctgtgc
     7321 gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac aatcaaagcg ccaatcatcc
     7381 agctatcatt ccttatgaaa gaaatagcca gacaaagaat cccacaaaca agatctgccg
     7441 tcattaaaat cttacgacga gaaaaacggt ctgaaataac tccgccaaag ggattgacga
     7501 gaatagatgt gacgagctca gaaatctgat acattcctaa aactgtctgt cctatagtcc
     7561 ccatagaagc caaccagaca ctatttccat aatcatagag catatttccc attttattga
     7621 tagccccacg gctaatcaac tgcactgcat agcgattcat attaaagctc ctctcaaatt
     7681 ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt tttcccttat ttgggaaaat
     7741 taacttttga caaatttttc gtagtgttcc tgataatagg ctacttgctc tggaagacct
     7801 aacacatcaa aaatatgcat ggcctcttgc atctgcttac agccttcttt acactgtcct
     7861 ttttgatata aggcaaaacc ttttaaataa tggaaaacat tacgctcata aagcttaata
     7921 cctttgtcaa taatcttctc tgtataagcc tcaaaatagt tggcattata aaaagaagaa
     7981 tgctctaaac aatgctggta acaattgagg gccaaaatca acactaatct cttatggcga
     8041 ctaatctctt ggtaaaattc ctccctctcc ataacttctc taccaatccg agtgacatag
     8101 tctacatcgt agaaactata gaggttaccg aaaagaatca actcatacat ggtccattct
     8161 tctgttttga agagataatc tgctacctta tccaaatcat cctgcttcat atcataactc
     8221 gcatctcttt gacaaatcag accttgtagc aaaatccagt tcagctcaaa ataaagggga
     8281 gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa gcttttgaaa acctgcaata
     8341 tcgtttgaat agtaaagtgg gataatctgt gccatcatag acacatgttc atgattatga
     8401 aaattccttg ccttatccat gaaattttcg attgttacat gaatgttatc caaaatctca
     8461 aagaaacggg agactgccag gtcagactcc ccaagctcaa agcgagataa ctgagaggta
     8521 gagcaggatt cgcctgctgc ttcctttaaa gaataatttc cacttgttcg aaattcacga
     8581 aatacttttc caagatgttc catctttaca cctgctctga taattcttcc cactcaagca
     8641 tagcttcttc ctgacgatgg ctgattttgt ccagctcagc ctgtaattcc atgagtttgt
     8701 cggcatcgtt tgtttccaac atttgttcag aaatggcttg gctttgactt tctagctctt
     8761 caatttcagc ttctagactt tcgatttgtc gcatgagttt gcgaacttct ttttgacttt
     8821 ctttctgggc ctgatagtca ttgactggac ttgcttcctt tgcttgattg ctagttgaag
     8881 cttcctcagt ctgactcatt tctgctgttg ctttcttctc aacatagtag tcgtaatctc
     8941 caaggtagag agttgaacca ttctcagaca attccaaaac atgagttgcc acacgattga
     9001 taaagtaacg atcatgactg acaaacagca aggttccatc aaagtcaatc aaggcatttt
     9061 ctagcacttc cttactatca atatccaagt ggttggtcgg ctcatccaga atcaaaaagt
     9121 tattgttttc catagacaat ttagctaaaa gcaaacgagc tttttcgcca ccagatagca
     9181 tgccgactga ttttttaaca tcatctcctg agaaaaggaa ggctccaaga cggttgcgga
     9241 tttcaacttc tggtgtcagt ttgaaatcat tccagagttc atccagcacc gtattacttg
     9301 gtgtcagctt gctttgggtt tggtcatagt aaccaacctc aacattagcg ccaaagcgct
     9361 tttctccctt gataaaagga atctggtcca caatagactt gataaaggtt gacttgccga
     9421 taccatttgg accaacgata gcgacagcat tcatcttacg aagatctagg ttaatcggtt
     9481 gtgacaagac ttccccgtca tagccaacag ctgcattttc aacagtcaaa acaacattgc
     9541 ccgacgtttt ttcagactgg aaggtcatgt tggctgattt cttgccagct tcaggcttgt
     9601 ccaaacgttc cattttttcc agttgtttac ggcgagattg agcacgttta gtcgttgaag
     9661 cacgaactag attgcgattg acaaagtctt ccagagcagc gatttccttc tgttgctttt
     9721 catagttttt tgcctcagta actagctttt gctccttcaa ttcgacaaaa cgagagtaat
     9781 tccccacata gcgatccaag gaatgcttgg tcaaatctag cgtaattgtc gcaaccttgt
     9841 ccaagaaata acggtcgtgg ctgacgataa tgagggcacc gctatagttt accaagtaat
     9901 tctctagcca ggcgatggtt tcaatatcca agtggttagt tggctcgtcc aagaccaaga
     9961 gattgggctt ttcaaggagc attttggcaa gtgccaaacg agtattttga ccaccagaaa
    10021 gctcagcaat tttcatctgc cacatagact cgtcaaactt gaatccattc aaaatcgctc
    10081 gaatatcagc ttcataggta aagccacctg cttggcgaaa attctcagat aagcggtcat
    10141 aatctgacat cagtttatcc aaatcctcac cagacttttc acccatctcc agctccatct
    10201 gacgcagttg tctctccgtc cgacgcaaat cattaaagac atgaagcatt tcatcgtaga
    10261 tggtattttc agactcaaaa cggctatctt gggctaggta agacagagaa atatcttttt
    10321 tcttattgat ttctccgcta gttggctcct cttctccaac taaaatcttc aaaagagtag
    10381 acttacctgc accatttttc ccaacaagag caatccgatc tcgttcatca acctgcaggt
    10441 tgatattatc gaaaagaacc tctcctgcaa aagaacgttc aattttatta gcttgtaaaa
    10501 taatcataca agtagtatag catgtttccc taaggcattc aagataatcg taagtctttt
    10561 agtacaactt ttataacata aaa
//
LOCUS       DAVKXA010000059        10455 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKXA010000059 DAVKXA010000000
VERSION     DAVKXA010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.059"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            80..760
                     /locus_tag="VW883_001828"
     CDS             80..760
                     /locus_tag="VW883_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0274917.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLETISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            720..1100
                     /locus_tag="VW883_001829"
     CDS             720..1100
                     /locus_tag="VW883_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0274918.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            1110..1397
                     /locus_tag="VW883_001830"
     CDS             1110..1397
                     /locus_tag="VW883_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0274919.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            1398..2156
                     /locus_tag="VW883_001831"
     CDS             1398..2156
                     /locus_tag="VW883_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0274920.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLIHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAITDRIIFLDQGKI
                     AEEGTAQAFFTNLQTKRAQEFLNVFDFSQFGSYL"
     gene            2168..3039
                     /locus_tag="VW883_001832"
                     /pseudo
     CDS             2168..3039
                     /locus_tag="VW883_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(3126..3773)
                     /locus_tag="VW883_001833"
     CDS             complement(3126..3773)
                     /locus_tag="VW883_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0274921.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(3770..4468)
                     /locus_tag="VW883_001834"
     CDS             complement(3770..4468)
                     /locus_tag="VW883_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274922.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAIVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(4478..5229)
                     /locus_tag="VW883_001835"
                     /pseudo
     CDS             complement(4478..5229)
                     /locus_tag="VW883_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5229..5993)
                     /locus_tag="VW883_001836"
     CDS             complement(5229..5993)
                     /locus_tag="VW883_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274923.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(6089..6492)
                     /locus_tag="VW883_001837"
                     /pseudo
     CDS             complement(6089..6492)
                     /locus_tag="VW883_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6672..7304)
                     /locus_tag="VW883_001838"
     CDS             complement(6672..7304)
                     /locus_tag="VW883_001838"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0274924.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(7338..8039)
                     /gene="pyrF"
                     /locus_tag="VW883_001839"
     CDS             complement(7338..8039)
                     /gene="pyrF"
                     /locus_tag="VW883_001839"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0274925.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNIHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            8360..8452
                     /locus_tag="VW883_001840"
                     /pseudo
     CDS             8360..8452
                     /locus_tag="VW883_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(8774..9487)
                     /locus_tag="VW883_001841"
     CDS             complement(8774..9487)
                     /locus_tag="VW883_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0274926.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(9480..10319)
                     /locus_tag="VW883_001842"
                     /pseudo
     CDS             complement(9480..10319)
                     /locus_tag="VW883_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT         3451 a         2154 c         1718 g         3132 t
ORIGIN      
        1 gcaataaaaa tagatattat ccaaagaaga ttttaagtgc tacaataact gtattatttc
       61 tagatgggag gttctatttt tggattggtc cattgttgaa caatatctac cactatatca
      121 aaaggcattc tttctgacct tgcatattgc agtttgggga attttgggat cctttctgct
      181 cggtttaatc gttagtatca tccgacatta tcgaatccct gttttggcgc aagtagcgac
      241 agcctacatt gaattgtcac gtaatacgcc ccttttgatt caactcttct ttctctactt
      301 cggtcttccc cgaatcggca ttgtcctatc ttcagaagtc tgtgcaacgc ttgggcttgt
      361 ctttttagga ggctcctata tggcagaatc tttccgaagt gggctggaaa ccatcagtca
      421 aacccagcag gagattggcc tcgctattgg tctgacacct ctacaggtct ttcgctatgt
      481 ggttcttccg caagcaacag cggtggcact cccctccttt agtgccaatg tcattttcct
      541 tatcaaggaa acctctgttt tctcagcagt ggctttggcc gacctcatgt acgtcgccaa
      601 ggatttgatt ggtctctact atgagacaga cattgcgcta gctatgttgg tagttgctta
      661 tctgatcatg ctgctaccca tctcactggt ctttagctgg atagaaagaa ggacccgcca
      721 tgcaggattc gggaatccaa gtactctttc aaggaaataa tctcctgaga atcttacagg
      781 ggttgggcgt tacgattggg atatccatcc tgtctgtcct cttatccatg atgttcggaa
      841 cagtcatggg aatcatcatg acctcccatt ctagaatcat acgattttta acacgattgt
      901 atctggactt tatccgtatc atgccccagc tggtgctact cttcatcgtt tactttggct
      961 tggctcgaaa ctttaatatc aatatctcag gtgagacttc agctattatc atttttaccc
     1021 tctggggaac agctgaaatg ggagacttgg tacgtggagc tatcacttct ctccctaaac
     1081 atcagtttga aagtggatag gcactcggct tgactaatgt tcaactttac taccacatca
     1141 tcatcccaca agtcttaaga agactgctac cgcaggctat caatcttgtc actcggatga
     1201 ttaaaaccac ttcattagtt gttttgattg gggttgtgga agtgaccaaa gttggacaac
     1261 aaatcatcga tagcaatcgc ctgaccatcc caactgcttc attttggatt tatggaacca
     1321 ttctagtctt atatttcgca gtttgctacc ctatttccaa actatccact cacttagaaa
     1381 aacattggag aaactaaatg tctgaaacta tcttagaaat caaggaacta aaaaaatcct
     1441 tcggagacaa tcccatcctc caaggacttt ctctagaaat caaaaaaggg gaagttgttg
     1501 tcatcctggg gccatctggt tgtgggaaaa gtaccctcct tcgttgcctc aacggcttag
     1561 aaagtattca aggtggagat attcttctgg atggtcagtc tatcgttgaa aataaaaaag
     1621 attttcacct agttcgccaa aagattggca tggtctttca aagttatgaa ctctttcccc
     1681 atctggatgt cttacaaaac ctcatcctag gccctatcaa agctcaagga agggacaaga
     1741 aagaagtaac ggaagaagct ttgcaattac tagagcgtgt cggtttgctg gataaacaac
     1801 atagctttgc ccgtcaatta tctggtggac agaagcaacg tgttgcaatt gtccgtgccc
     1861 tcctaataca tccagaaatc atcctttttg acgaggtgac tgcttcgctg gatccagaaa
     1921 tggtgcgtga ggtgctggaa cttatcaatg atttggccca agaaggccgt accatgattt
     1981 tagtaaccca cgaaatgcag tttgcccaag ccattactga ccggattatc ttcctcgacc
     2041 aagggaaaat cgctgaagaa ggaacagctc aagccttctt taccaatctg caaaccaaac
     2101 gagcccagga atttttaaac gtctttgact ttagccaatt cggctcatat ctatagagga
     2161 gattcttatg aaactattca aaccactctt aactgtttta gcacttgcct ttgcccttat
     2221 ctttatcact gcttgtagct caggtggaaa cgctggttca tcctctggaa aaacaactgc
     2281 caaagctcgc actatcgatg aaatcaaaaa aagcggtgaa ctgcgaatcg ccgtgtttgg
     2341 agataaaaaa ccgtttggct acgttgacaa tgatggttct taccaaggct acgctacgat
     2401 attgaactag ggaaccaact agctcaagac cttggtgtca aggttaaata catttcagtc
     2461 gatgccgcca accgtgcgga atacttgatt tcaaacaagg tagatattac tcttgctaac
     2521 tttacagtaa ctgacgaacg taagaaacaa gttgattttg cccttccata tatgaaagtt
     2581 tctctgggtg tcgtatcacc taagactggt ctcattacag acgtcaaaca acttgaaggt
     2641 aaaaccttaa ttgtcacaaa aggaacgact gctgagactt attttgaaaa gaatcatcca
     2701 gaaatcaaac tccaaaaata cgaccaatac agtgactctt accaagctct tcttgacgga
     2761 cgtggagatg ccttttcaac tgacaatacg gaagttctag cttgggcgct tgaaaataaa
     2821 ggatttgaag taggaattac ttccctcggt gatcccgata ccattgcggc agcagttcaa
     2881 aaagacaacc aagaattgct agacttcatc aataaagata ttgaaaaatt aggcaaggaa
     2941 aacttcttcc acaaggccta tgaaaaaaca cttcacccaa cctacggtga cgctgctaaa
     3001 gcagatgacc tggttgttga aggtggaaaa gttgattagt cattaactct taaaaggaac
     3061 tggattttaa gctccaatcc ctttttaaga ttttacctat aacatcctga gtctatctaa
     3121 gatgttcaat ctgaacacag tgtacatact ttatcttcta ttgcatatac tttatcacat
     3181 aagatacgaa tatcctcttc actatgacta gcaatcaaaa ttgttgtccc tttttcacta
     3241 gagagctttc taaacaatgt tctcatattt tctacacttg atttatccaa ggcattcata
     3301 ggttcatcta gtaaaagaat agagggattc tccataattg cttgagcaat ccctagcttt
     3361 ttcctcatac ctagcgaata agttttaact ttctggtctt tttgctcata tagaccaact
     3421 attttcagtg tatcattgat ttcctgatta ccaactactc ctcgtatgct tgccaaatat
     3481 tgtaaattct taaagccact ataataattt ataaaaccag gttcttcaat caaagctccc
     3541 aaattagctg gaatttttct ctcaggaaca atattttccc cattgattaa cacttctcca
     3601 taagacggac tatataaacc agctattaat ttaaacaata cacttttccc tgagccattc
     3661 gcaccagtaa ttcctataat ttccccctgt ttacaactaa agttaaggtt ttgaaaaaca
     3721 catgtttttt ttaatttcaa ctcaatattt tttaatataa ttatttcatt cattctataa
     3781 acctcctctt ttgacgagtg aaatagaaaa tgctttgaaa aagaaagact aaaaatagca
     3841 actgaagaaa taaatctcgt cctatatctc cattccctcg attcaaaata taaaatagat
     3901 aattagttcg atttcctaca aatagaccac caaacacaat catgagtaaa aagaaactaa
     3961 cgcaagcaaa gttcatttgt acattcgctc ctagtgcgta taacataaag caaaacaaga
     4021 ctaacacaca agcattcaaa gaatcaacta taaacaaaac tcctatatcc cagtttggta
     4081 actgtaacat aaattgaatc actagaactt ttaccatgat taaaatgagt ccataaagaa
     4141 aacaggtcca aatctgatac ctaatccaga gcttaataga agaaaatcga atcacttcca
     4201 taaagaaatc ggatgctctt ctacgatata caattgctag aaaaaatgta tgaataataa
     4261 accaatgaag caaccatata gataagacta aaaaagagtt ttgactcaga ttaggccctt
     4321 ttaaaatttc tataacaagt ctatcatttc cttctaacca ataccataat cctaaacaaa
     4381 tcaatatcca aaaaagaaca taaccccaaa agtacttggt atagattatc tgattcaacc
     4441 tccacatgtg actacttaac tttcccattt ccaactttta cactctcctc cagtttctat
     4501 gaacagaaaa tacagtcaat ggaattatga tagatagtaa tgtaagccaa taaatcaatg
     4561 catacggatt ggaatttacc atatactgaa aaattggcaa taatccaatt atcccattgt
     4621 ccaactgata aatccagaat aaggattcta caaataaaaa agtaaacaga aatactaagc
     4681 tcatgtttga ttttttaaac caagaaaaac tgctaatagt aagtaaggat aaaaagaaat
     4741 agtatgctat ataagagaaa aaaatcctat aaagaaacta gcattgtttg caatacttat
     4801 accataaaat tctcttaaaa aatcaacctc ctttatctcc aaagagaagc taaaaccatt
     4861 actaaatgca attagaaaaa tcaataaaaa taaagtcgcc gtccaaatcc ccgtactaag
     4921 agctgctaat ttgaaactaa aactggtaaa gtgcttaatt gatttcagac gaatgcgaca
     4981 ctccaaccta ttaaaatagt tattcatcaa ataaaaaaag aacaatatat atgtgaacgg
     5041 aaagcaatat actccagtcg tcatatcttg aagtaaaact aagatccatt ctaatacatt
     5101 tggatggatt gaatattggt gacagcgcaa taaatatact gtactagata aaacacagga
     5161 tagcagtaat ataaaataaa ccaatactgc taagaaatct tttttataaa attgaacaaa
     5221 ttgtttcatt atacatagtc ctctgaatgt agaaaaaatg taccataaac aaccaaacaa
     5281 ctaacaaata aaataaaagc aagatgccca ctaactaagg aaagactgat atctttctga
     5341 tatcccaaag ctagcgttgt cacaggttct aagtaagata gccctaaaat agcccataaa
     5401 ataccaccaa ccatcatata ggcaactggg atgaaaatag ctcctaattt tttcttcact
     5461 agcaaagcac tagctagtcc aaaaatagag aacacagcgc cccaaactcc ataccagaga
     5521 gtcgtcacaa gactatagag caactgatta gaatcaaata attcttttaa ggcaccacta
     5581 taatctccaa tataaatttc ctgataagga gtcactaaaa gattaattcc taataataat
     5641 aaatagggga gaaaaaagac tagaaaagaa gaaataatta cagtactacc cacaatagcc
     5701 agatacttct ttttagaaat tcgacacaat tgtgctgtta gaaaatgact ctcagcatcc
     5761 tctattatct gactagaata gggcagtgta cagataagtg cagctactag gctaatcggt
     5821 gaaaatcctc gaatagaaga agcggcaaaa aaaatcgata aaccttcaat tttataaata
     5881 ccattgaaag caaggaaatt tcctaaactc atgcaaagaa gggtcaaaaa taaagacata
     5941 taaaaccgag gtgattgaac gactcgtaca agattacaaa tgaaaaattc catcccaact
     6001 cctccttata ataaaaatag ggtgtagcat tcttttttca tgctacaccc acaatcaacc
     6061 atctttaagg cttactctga caagtaagtt aataagaatc tgaactccaa gaacctgaag
     6121 tatgaattct tacatgattt ccaaattgtg gcgccatagc taatctagta ccagaaccaa
     6181 tataattgtc accacctcca ttatagtaca tgacaatcct agagccagac cccaatgaat
     6241 ataccggggt aatatctgac ccactatagg cgctacgaat agaggtattt aaccttttac
     6301 cgccaccagt gctgtcacta ttattaattc cagcagaggc gttttctttc tcaagctcac
     6361 tagttgtatc cgaaccccaa cgcggcaacg ttaaatcata atttccaatc tgtctagcta
     6421 aaactgtagg gagaaacaaa ctagatgcaa ttgtaactac gcaaaaaagg aatatatttt
     6481 tcttcttttc atgacatcgt cctcttaaga agtgataaac aagatagttg attgatcaat
     6541 ttgatacata ttacattttc attatatcaa taaaagaaag cgttgtcaat tattttattt
     6601 aaaatattgt catattttaa ataaaatggt aaaagagact cggtagcctc gtctctcttt
     6661 atcttactga cctaaccttc ttgccaattt tcttggtctt ctttaaagcg ttttagaaga
     6721 tcaaggccct ctggcgtgat gtaaccttct tcttgggcta gatggataag ctcgctatag
     6781 tttgaaagcg tcacaagttt aacaccagca tctgcaaagt tcttatctgc ttttggcaat
     6841 tggtagctga aaatcgctac aactccaagc acatctgctc cttctcgctt ggctgctgct
     6901 acagcttcaa gaactgaacc acccgttgaa ataaggtctt caaccactac cattttttga
     6961 ccttgagcta cgcgaccttc gatttgatta ccagctccat ggtcttttgg tttgctacgg
     7021 atgtaggcaa aaggcaagtc catcttatca gcaataatgg ctccgtgtgg aatccctgct
     7081 gttgcagttc ctgcaatcac ttctacttca ggaaaggctt ctttgatagc ttccacaaaa
     7141 ccattttcaa ttagggtacg agtttctgga taggctagtg tcacacgatt atcagtgtaa
     7201 atcggtgact tgataccaga tgcccaagtg aagggttcct ctggtttgag gtaaacggct
     7261 tggattttca agaggtggct agcgatatct ttagcaagtg tcatggtatt ctccttttat
     7321 ttttctaatc tagttcttta attccagtcc tgtgtccatt catccttgat ggcatgataa
     7381 gctgcaacag gatcctcagc ttgggtaatg ggacgtccca ctacgatata gtcactgccg
     7441 atttgatagg catcagcagg tgtcatgact cgtttttgat ctccaactgc aacaccagct
     7501 ggacgaatcc ctggtgtcag acagataaaa tctggattgg tagcctgctt gatgacttgt
     7561 acttcctgag ccgagcaaac aacaccatcc aagccagctt cagctgtctt cttggcatag
     7621 tgaatcacag actcttgcag actggtttgg atattttgaa actcctgcat ctgagcttct
     7681 gacgttgatg tgagctgcgt tacagcgatc aatttggctt gacttccaag accttcacgc
     7741 gcagccttca tcatctctac accaccagcc gcatgaatat tggtcatatc cacaccaagc
     7801 tgagatagga tcttcattgc tgacttgact gtattaggaa tgtcatgaag tttgagatcc
     7861 aaaaagacac tatgacccaa accttttaag taggacacaa tctcaggccc cgctgcgtaa
     7921 taaagctcca tccctacctt gagataaagg ctttcttctg ctgggaaaag agctaaaaat
     7981 tccttgaccg cctcaaaact aggaaaatca agagcaatga ctggacgatg ttctcgcata
     8041 ggtttctcct tttaccttta ctagtgagag agtctggcca acagaagcca cgaaaaaagg
     8101 aacctgccaa cagcaaggtt ccacgaaaaa tgggtagtct ccaccctttc accgtctaac
     8161 cttagctgcc tctctggact gctttaaagg ttttctatta ttctattatt tctactagca
     8221 cttgtcaagt aaaaacttag tcacgtatgt gttgactgct attgaacacc tcacaagact
     8281 ctttccaaaa gaatagttaa agactttcac ttaggacaga gaaaaagagt ttgcttgtta
     8341 ccctttaatt gaacaaatgg gaattctgtt ttattttgcg gatacctatt catcttggca
     8401 aaggggaagt aatgagaatg cgaatggact tcttcgtgag tattttctta aaccgatttg
     8461 gcaacaatta ccgaaaaaat ccttaatggt gctttgctag cttattaatc accgtcccca
     8521 aaaatacttg gattacaaga caggttttga agcacttata gaggagattt aaaaatgttg
     8581 cattttttat tgcaatttat cagttatctt atcacccaaa acttctgcaa ttagtatgag
     8641 cactattgtt atttttcttt tttcgtacac tcaaatcaaa atatagcaat aagactattc
     8701 tgtagaattg ctgtcaaaaa gatcagttca tttttccttc ccacttgtgt ttataatcat
     8761 taaaataact caattaagaa attttctttt tcctaatagt tatcgtaatt aaagttaata
     8821 gaagaacaat ccaaataagt agtgttagat taggaattag agttttattc catgaaaatc
     8881 cctcccattt tgtgaaaaac ttagtaaaca gtcccataaa actataatct gttatcttcg
     8941 caactgtctt atccaaacca gatagcatcg gtaagaaagc aactaaaatc atagcaggaa
     9001 gactgataac ctgagctact acttggctct tcgcggttaa acctatcaat aaatagaata
     9061 aaatgatgga taaagaggtt agaagaacga ttgtaatata attaaaagta tgtacaattg
     9121 taactcctaa aataagagga gtagttccca taatcacaaa agttagcaaa aaaggaagaa
     9181 acatcgttga taaaatgtat tcggatcctt taacaccact caacagaaga gtttgtaaat
     9241 tgtacttttc tttttcttca gacaagataa tagttatagg acttccaaca gccaaagcca
     9301 aagaaaaagg taaacacatc atcaaaagaa ctaatgcctg ttgatcgttg accttcccct
     9361 gtgtttccat aagatattta taaaaatatg tgaaagcaaa aggcactaaa acttgcaata
     9421 aaatactctt attggaaagg atgatttgac aacgcaacca taccaaagcc agaaaccgtt
     9481 taagcattta gctttcctcc tgttaatgtg ataaaaatat cttctaaagt aggctcacat
     9541 gaatgaattg aaaaaatatt ttccagatca gcctgagata cctgttctag tgatgtaaaa
     9601 tcaaaagtta tctgattccc attataatct gtaaccttaa tctttttatc tttattatat
     9661 ctttgaatga gttcagaagg agctccttgc tcaactaatt tccctttatt taataaggca
     9721 acataatcac ataaaagact tgcttcattc atatcatgag tcgttagaaa aatcgttgtc
     9781 cctgctgttt tcaattctaa aattaactca tgaattgttc gagaagttgt gggatctaga
     9841 cctgaggtcg gttcatccag aaagagtaca gcgggtttgt tgataagagc tcgtgctaaa
     9901 agcattcgtt gcctcattcc agtggataat tttcctgcta ccatcttgcg actatcatat
     9961 aatcctactc gctttaacaa attatcaaca cgtaatttac taatattata aaatttacta
    10021 taaaaaagaa gattgttata cagagacatt ttctcataaa atccacttgt atcgctaacc
    10081 aatccaattc tctttaattc accgcttgtt aaattttgag atttttgtcc caaaataata
    10141 gattgtcctt tatcggcaag gaactgccca gtcagaatat taatcgttgt ggtctttcca
    10201 gaaccagatg gtcctaaaaa tccaaaaatc taaccttctt taacagtgaa gcttatatta
    10261 tttaaagcta ttttatcacc aaaacttttt gataaatggc taacttcaat catactcatt
    10321 gcacctcctt tatattctac atttttactt aacatctatt tacttatctt tatcaaataa
    10381 acgtcttaaa aaaaacaata acattaagca tataaccgtt agcaagattg tttcaatatt
    10441 attgataata cgata
//
LOCUS       DAVKXA010000060        10359 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKXA010000060 DAVKXA010000000
VERSION     DAVKXA010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10359
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.060"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..175
                     /locus_tag="VW883_001843"
     CDS             <1..175
                     /locus_tag="VW883_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0274927.1"
                     /translation="NRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTL
                     ITGKNGTGKSTLL"
     gene            complement(541..1851)
                     /locus_tag="VW883_001844"
     CDS             complement(541..1851)
                     /locus_tag="VW883_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0274928.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2088..2960
                     /locus_tag="VW883_001845"
     CDS             2088..2960
                     /locus_tag="VW883_001845"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0274929.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3091..3937
                     /locus_tag="VW883_001846"
                     /pseudo
     CDS             3091..3937
                     /locus_tag="VW883_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            4023..4973
                     /locus_tag="VW883_001847"
     CDS             4023..4973
                     /locus_tag="VW883_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0274930.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYNDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            5150..6157
                     /gene="gap"
                     /locus_tag="VW883_001848"
     CDS             5150..6157
                     /gene="gap"
                     /locus_tag="VW883_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0274931.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6225..7061)
                     /locus_tag="VW883_001849"
     CDS             complement(6225..7061)
                     /locus_tag="VW883_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0274932.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTFSNTFEKELKK
                     NG"
     gene            7187..9382
                     /locus_tag="VW883_001850"
     CDS             7187..9382
                     /locus_tag="VW883_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0274933.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGVYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKSQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            9435..9587
                     /gene="rpmG"
                     /locus_tag="VW883_001851"
     CDS             9435..9587
                     /gene="rpmG"
                     /locus_tag="VW883_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0274934.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            9597..9773
                     /gene="secE"
                     /locus_tag="VW883_001852"
     CDS             9597..9773
                     /gene="secE"
                     /locus_tag="VW883_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0274935.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            9828..>10359
                     /gene="nusG"
                     /locus_tag="VW883_001853"
     CDS             9828..>10359
                     /gene="nusG"
                     /locus_tag="VW883_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0274936.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         3244 a         1790 c         2250 g         3075 t
ORIGIN      
        1 aaacagaact gtttcttttg ctattagttc aaaaggagaa aaaatgaaag tagaaaatat
       61 ttcgtatagg gtggatcatc gtatattgtt tgataatatt tcttttgata cttcgagttc
      121 aggcgtgaca ttaattactg gtaaaaatgg tacaggaaag tcaactttac tatagtagat
      181 tgaaactaga atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactatcc
      241 tgatctattt gtcctgttct tatttcattt cactatatct caaattgagt atgacgaagt
      301 gcgctcccat gtcctgggaa cgcactttct tcatattttt catattcttg aatccatcga
      361 taaagactat tgggatgaat ttttaaagtt gaactaatca tttttacagg atgagattta
      421 cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact tttcctcgtt
      481 tccacttaat tttgtgtcta ctttattata ccaagtccac ccttaagtta gataataaat
      541 ctaacttaag gaagctagaa ggatgagaat ccaggtggtc aagagtccca aacttaagct
      601 gatggggaca cccagaataa tttgcttttt gaaggcaagg ccacgttcct ctatattggg
      661 aagtgagagt tgaatgagag aaccagctga tgaaaagggt gagatattag tagatagagc
      721 gccaataacg gtggctgttg tgagtaagtg aatatcaatc tgaggatttt gagcactgat
      781 gatagcaatg atgggaaaga gggctggagc tacaacggat agggtggaac taaagagtga
      841 catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa tggttgttgt
      901 catgaggtgc cctatcagtg tgactaaacc tgacttgacc gctagagaca ttagtaagct
      961 catgccgcag agcatgataa ttgtagccca gggaacctta gctaaaatgg cttcttgctt
     1021 ccctaatttg agccttaagg cgaggcagac catgagtatt gagacaaagc caatatcaaa
     1081 tgttttttga taagtagcta tccaggcgat gtttgggaaa atgagatgca acaagggaaa
     1141 aagccaaacc aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct
     1201 gaggagtggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac tatagtgact
     1261 gtaacaggat aataaaagca agacgatgag tgggtagata atgctgacga taaagatatg
     1321 attgccaagt gaaaaagctt gctcttccca tcccatttgc ttaaacaggc cttgaaagac
     1381 aatgcctgag ctactggtta tcaaattagc ccctcctgaa gctccccaat tgacggcttg
     1441 agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta gaggacagca
     1501 aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg ccatcaggta
     1561 taaaatcatg tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt gttgagccaa
     1621 aacatcaaga gtaccgttag ttgttgcaac gttataaaag agagagacgc taaaaatggt
     1681 aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc ccatgagagt
     1741 ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt tggtgcggta
     1801 accaattcca atggctagag caatggcgct aatcattatt aaatgaatca ttgaattgtc
     1861 ctttcagtta gaatatggaa ataggttggc aattttggcg ctcaaaagac cacctgtttc
     1921 ctattggtac ttgactatta tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac
     1981 acttgttaga attaaaaatg aggtattcag gcttgtgatt tcctatggaa gttaatagta
     2041 attgcctcta gtgcttacaa gtgatattaa aaatagagga cttagtgatg tcaatcattt
     2101 caactgattt aacccctttt caaatagatg atacattgaa agcagccttg cgagaagatg
     2161 ttcattccga agattacagt accaatgcca tttttgatca tcatggccaa gccaaggtgt
     2221 cgctttttgc caaggaagct ggtgttttag cgggactaac cgtttttcaa agggttttta
     2281 ccctatttga tgccgaggtg accttccaga atcctcatca atttaaggat ggggatcgtt
     2341 tgactagtgg cgatttggtt ttagaaatca taggctcggt gagaagtctc ttaacatgtg
     2401 aacgcgttgc cttgaatttt ttacaacatt tatcagggat tgcttcgatg acagctgctt
     2461 atgtagaagc cttaggcgat gattgcatta aggtatttga tactcgaaaa actactccta
     2521 atttacgtct ttttgagaaa tatgccgtga gagttggcgg tggctataat catcgcttta
     2581 atttatcaga tgctatcatg ctaaaagaca atcacattgc ggcagtaggt agtgttcaaa
     2641 aggcaattgc tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg
     2701 aaagccttgc tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc atgttggata
     2761 atatgtcatt ggaacagatt gaacaggcca ttaccctaat tgcaggacgt tctcggattg
     2821 aatgttctgg aaatattgat atgaccacta ttagccgttt tcgtggttta gcgattgatt
     2881 acgtctccag tggtagttta acccatagtg ctaagagtct tgatttttcc atgaagggtt
     2941 taacctacct tgatgtctaa gttgtaaaat aaactaactt tttaaaggat gtctttcctc
     3001 tagaacgagt tttatgtcag atagtttaaa cgcctcttca aatatagtaa aatgaaccaa
     3061 aaatagtaca caatgtggta taatcttctt atggcatatt caatagattt tcgtaaaaaa
     3121 gttctctctt attgtgagcg aacaggtagt ataacagaag catcacacgt tttccaaatc
     3181 tcacgtaata ccatttatgg ctggttaaag ctaaaagaga aaacaggaga gctaaaccac
     3241 caagtaaaag gaacaaaacc aagaaaggtt gatagagata gacttaaaaa ctatcttact
     3301 gacaatccag acgcttattt gactgaaata gcttctgaat ttggctgtca tccaactacc
     3361 atccactatg cgctcaaagc tatgggctac actcgaaaaa aagaaccaca cctactatga
     3421 acaagaccca gaaaaagtag ccttatttct taaaaatttt aatagtttaa agcacctagc
     3481 acctgtttag attgatgaaa caggattcga tacttatttt tatcgagaat atggtcgctc
     3541 attaaaaggt cagttaagaa gaggtaaagt atctggaaga agatatcaga ggatttcttt
     3601 ggttgcaggt ctaacaaatg gtgagttaat cgctccaatg acttacgaag agatgatgac
     3661 gagcgacttt tttgaagctt ggtttcagaa gtttctctta ccaacattaa ccacaccatc
     3721 ggttattatt atggataatg caagattcca tagaatgggt aagttagaac ttttatgcga
     3781 ggagtttggg cataaacttt tacctcttcc tccctactca cctgagtaca atcctattga
     3841 gaaaacatgg gctcatatca aaaagcacct caaaaaggta ttaccaagtt gcaatacctt
     3901 ttatgaggct cttttgtcct gctcttgttt caattgacta tagttcacgg atacagttgg
     3961 gaaagaagct attaaatatt tggagagtcc ttttgggatg aacatgtcaa atattactat
     4021 agatgggcaa gaaaagatgg gcaagaaatg gatctgagtc aaacgatgct tcttatgctc
     4081 aagtagtgag tctttataat gatacaagta tctctgttag taataatgag acggacaaag
     4141 tgttgactgg atccctctat actgaaacaa atgaacaggg attaacgatt ccaagcagtt
     4201 tactaaaaaa ttggaatgaa cagacaggaa aaaatttgac aactaatgat cttattggca
     4261 aatcagtctc agccagcatt gtagaaagtg ctgccgaaac tagtaagatt gctcaatttc
     4321 aaacgaagat tgtacgtgta atcaatgatg aagatgacat ggaggacagc aacagtttca
     4381 tgctgtctca tcaaatggaa acgattttga aagaggctgg atttacgaaa gctgtatctt
     4441 attttatctt ggaactcaaa gatccatcac agacaaaagt agtaacagaa gaattacaga
     4501 aaaataagaa gtatactgtg ctttctcaac agagagttct tgatattgtg attaccttta
     4561 ttcgtgttat tcagggatta ttgattgtgc tttcatcaca agctattgtg gtagcagcgg
     4621 ttatgattgg tatcattatt tacatcaata tcatgcaacg ttccaaggaa ataggtgtca
     4681 tgaaagcagt tggttatcag aatcgtggtg tcaaaggaat ttttatttac gaggctatct
     4741 ggattgtagg catcgccttg ctgctggcat ttttggttgc acaaggggtg ggaagtttgg
     4801 cgaatgcgat tgtaagtcac ttttacccat ccatcactaa ggtttttgaa ttaaatcttt
     4861 tatctgtttt aggaactcta gttttcgctc tattacttgg ttatgtctca gcctacttcc
     4921 cggcgcgtaa gattagtaaa atggatcctg tagaatcgtt acgctatgaa taataaggga
     4981 ttccttgatt tacagtctta aaaagaaact cacatagaaa aacaatggcc atacttgcaa
     5041 ttcaactcaa atagttgtat aataggtttg ttgaaaggtg atttgtagtg attcaagtta
     5101 ctcttttcac aataaaaatt tcatgatttt cataaggagg aaatcactaa tggtagttaa
     5161 agttggtatt aacggtttcg gacgtatcgg tcgtcttgct ttccgtcgta tccaaaacgt
     5221 agaaggtgtt gaagttacac gcatcaacga ccttacagat ccagttatgc ttgcacactt
     5281 gttgaaatac gacacaactc aaggtcgttt cgacggtact gttgaagtta aagaaggtgg
     5341 atttgaagtt aacggtaaat tcatcaaagt ttctgctgaa cgtgatccag aacaaatcga
     5401 ctgggctact gacggtgtag aaatcgttct tgaagctact ggtttctttg ctaagaaaga
     5461 agcagctgaa aaacacctta aaggtggagc taaaaaagtt gttatcactg ctcctggtgg
     5521 aaacgacgtt aaaacagttg tattcaacac taaccacgac gttcttgacg gtactgaaac
     5581 agttatctca ggtgcttcat gtactacaaa ctgcttggct ccaatggcta aagctcttca
     5641 agacaacttt ggtgttgttg aaggattgat gactactatc cacgcttaca ctggtgacca
     5701 aatgatcctt gacggaccac accgtggtgg tgaccttcgc cgtgctcgcg ctggtgctgc
     5761 aaacatcgtt cctaactcaa ctggtgctgc aaaagctatc ggtcttgtaa tcccagaatt
     5821 gaatggtaaa cttgatggat ctgcacaacg cgttccaact ccaactggat cagttactga
     5881 attggtagca gttcttgaaa agaacgttac tgttgatgaa gtgaacgcag ctatgaaagc
     5941 agcttcaaac gaatcatacg gttacacaga agatccaatc gtatcttcag atatcgtagg
     6001 tatgtcttac ggttcattgt ttgacgcaac tcaaactaaa gttcttgacg ttgacggtaa
     6061 acaattggtt aaagttgtat catggtacga caacgaaatg tcatacactg cacaacttgt
     6121 tcgtactctt gaatactttg caaagattgc taaataattc ttgagttgat agaaagcaag
     6181 gctttgtggt cttgcttttt tatatggaaa aatggatgac acgatcatcc attctttttt
     6241 aattcttttt caaatgtatt tgaaaaggta gtgaaagtta gcctctctaa agtaagtggg
     6301 tgggtaaagg aaagtcggaa ggcatgaagc ataagccggc ttgtctttga tttactatta
     6361 tagagagggt ctcccaggat aggaagatta tgatgcaaaa ggtgcacacg aatctgatgg
     6421 gttcgccctg tctttagctt gcaatgagcc aaggaagtct tgtttgagaa ttgctttaat
     6481 ctgcttacat gcgtttcagc atattgccca ttttttgcat caactattct ttttctacga
     6541 tcatggcgat cacgtccaat tttgtctctg aaaacaagtt cttttctgtt gatatttcca
     6601 tcaactagag cccaatattc tctagaaatc tcttttttct ccaataagcg attgagaatg
     6661 ggcaggataa aaggattttt ggcaaagaga actaagccac tggtttccat gtccagacga
     6721 tgaacgacat agcaggtttg gccaacataa gtactgacat ggttaagaag ggcaatttcg
     6781 tttggttgat taccatgtgt tttcatcccc tctggtttgt ttacaataat caagtgttga
     6841 tcttgataaa cttcctgcac taagtctggg ttgccccaag ggatcgtttt ttgggaataa
     6901 tcttcctcgt caaaagtcaa ctggcaaaca tctccaggat ttacgatttc gttccagtgg
     6961 acttcttctt gatttatcaa aatatgtttt ttgattctca aaaaatgacg gatttttcta
     7021 gggatgagga gttgttcctc aagtaattgc tttaccgtca tttgaggtag agaggcgggt
     7081 aatgtaaatg tgaattgcat acagatattg taacaaaaaa agccctattt ggataggaaa
     7141 tagctaaatt cttgtcttcc tatgatgaag atgataaaat aaacgcatga aattagataa
     7201 attatttgag aaatttcttt ctctttttaa aaaagaaaca agtgaactag aggactctga
     7261 ttctactatc ttacgtcgct ctcgtagtga tcgaaaaaaa ttagcccaag taggtccgat
     7321 tcgaaaattc tggcgtcgtt atcatctaac aaagattatc cttatactag gtttgagtgc
     7381 aggcttgcta gttggagtct atttgtttgc tgtagccaag tcgaccaatg tcaatgattt
     7441 gcaaaatgcc ttgaaaactc ggactcttat ttttgaccgt gaagaaaaag aggctggtgc
     7501 cttgtctggt caaaagggaa cctatgttga gctgactgac atcagtaaaa acttgcagaa
     7561 tgctgttatt gcgacagaag accgttcttt ctataaaaat gacgggatta actatggccg
     7621 tttcttcttg gctattgtca ctgctggacg ttcaggtggt ggctctacca ttacccaaca
     7681 gctggctaaa aacgcctatt tatcgcagga tcaaactgtt gagagaaaag cgaaagaatt
     7741 tttccttgcc ttagaattaa gcaaaaaata tagtaaggag caaattctaa ccatgtacct
     7801 taacaacgct tattttggaa atggtgtgtg gggtgtagaa gatgcgagta agaaatactt
     7861 tggagtttct gcatcagaag tgagtctgga tcaagctgcg actctggcag ggatgctcaa
     7921 ggggccggaa ctgtataatc ccttgaattc tgtagaagat tctactaatc ggcgcgatac
     7981 tgtcttgcag aatatggttg cagcaggata tattgataaa agccaagaaa ccgaagctgc
     8041 tgaagttgat atgacttcgc aattgcacga taagtatgaa ggaaaaatct cagattaccg
     8101 ttacccctct tattttgatg cggtggttaa tgaagctgtt tccaagtata atctaacaga
     8161 ggaagagatt gtcaataatg gctaccgcat ttacacagag ctggaccaaa actaccaagc
     8221 aaatatgcag attgtttatg aaaacacatc gctatttccg agggcagagg atggaacgtt
     8281 tgctcaatca ggaagtgtag ctctcgaacc gaaaacaggg ggagttcgtg gagttgtcgg
     8341 tcaagttgct gacaatgata aaactggatt ccggaatttc aactatgcaa cccaatcaaa
     8401 gcgtagtcct ggttctacaa ttaagccttt agttgtttat acgccagcag ttgaagcagg
     8461 ctgggctttg aataagcagt tggataacca taccatgcag tatgacagct ataaggttga
     8521 taactatgca gggatcaaaa cgagtcgaga agttcctatg tatcaagcct tggcagaatc
     8581 gcttaatcta cctgctgttg ccactgttaa tgatttgggt gtcgacaagg cttttgaggc
     8641 aggcgaaaaa ttcggactca acatggaaaa ggtcgaccgt gttcttggtg tcgccttggg
     8701 aagcggtgtt gaaaccaacc ctcttcaaat ggctcaagca tacgctgcct ttgcaaatga
     8761 aggtttaatg cctgaagctc attttattag tagaattgaa aatgctagtg gacaagttat
     8821 tgcgagtcat aaaaattcac aaaaacgggt gattgataag tctgtagctg acaagatgac
     8881 cagtatgatg ttggggactt tcaccaacgg taccggtatt agttcatcgc ctgcagacta
     8941 tattatggca gggaaaactg gaacaactga agcagttttc aatccggagt acacaagtga
     9001 ccagtgggta attggttata ctccggatgt agtgattagc cactggcttg gctttcctac
     9061 cactgatgaa aatcactatc tagctggctc tacttcaaac ggtgcagctc atgtctttag
     9121 aaacattgcc aataccattt taccttatac gccaggaagt acctttacgg ttgaaaatgc
     9181 ttataagcaa aatggaattg caccagccaa tacaaaaaga caagtacaaa ccaatgataa
     9241 tagccagaca gatgataatt tgtctgatat tcgagggcgt gcgcaaagtc tagtagatga
     9301 ggctagccgg gctatctcag atgcgaagat taaggaaaag gctcaaacaa tatgggattc
     9361 gatagtcaat ctatttcgtt aagatgcttg tcaaagccta gctttcttgt tataatggat
     9421 aagatggagg cgttatggca ctaaaaaaag caagcctagc ttgtgcggtt tgtggttcga
     9481 gaaactattc aatcaagatc agcggaaacc ccaagcctac acgactagaa gtaaataaat
     9541 tttgtaagca ttgtggcaag tacactacac acagagaaac gagataggag agagcgatgc
     9601 gttttattgg agatattttt agacttctta aagacacaac atggccaact cgcaaggaaa
     9661 gctggagaga ttttcgttct atcatggaat acacagcttt ctttgtagta attatttaca
     9721 tttttgacca gttgattgtt tcaggtttga ttcgatttat taacattttt tagaagatta
     9781 gtggagttaa ttacactaga aatcttctat ttatgaaagg aaatatcatg gatagttttg
     9841 ataaaggatg gtttgtttta caaacttatt ctggttatga aaataaggtg aaagaaaatc
     9901 tattacaacg tgcacaaacc tacaatatgt tggataatat tctacgcgtt gaaattccaa
     9961 cacaaacagt gcaagttgaa aaaaatggaa agagaaaaga agtagaagaa aatcgctttc
    10021 caggttatgt tcttgtagaa atggtcatga cagatgaagc ttggtttgtt gttcgaaaca
    10081 caccaaatgt tacaggattt gtcggatcac acgggaacag atcaaaacca actccattat
    10141 tggaacaaga aattcgtgac attttggtat ctatgggaca aactgttcaa gaatttgatt
    10201 tcgatgttga gattggtcaa actgtacgta ttattgatgg tgcttttgca gactacactg
    10261 gtaagattac agaaattgat aataacaaag tgaaaatgat tatctctatg tttggtaatg
    10321 acacagttgc agaagtaaac ctaaaccaaa tcgcagaat
//
LOCUS       DAVKXA010000061        10119 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKXA010000061 DAVKXA010000000
VERSION     DAVKXA010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.061"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            402..785
                     /locus_tag="VW883_001854"
     CDS             402..785
                     /locus_tag="VW883_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0274937.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            837..1526
                     /locus_tag="VW883_001855"
     CDS             837..1526
                     /locus_tag="VW883_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0274938.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1568..1801
                     /locus_tag="VW883_001856"
     CDS             1568..1801
                     /locus_tag="VW883_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274939.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            1952..2563
                     /locus_tag="VW883_001857"
     CDS             1952..2563
                     /locus_tag="VW883_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0274940.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMYGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2724..3518
                     /locus_tag="VW883_001858"
     CDS             2724..3518
                     /locus_tag="VW883_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0274941.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3515..4150
                     /gene="trmB"
                     /locus_tag="VW883_001859"
     CDS             3515..4150
                     /gene="trmB"
                     /locus_tag="VW883_001859"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0274942.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4276..4755
                     /gene="rimP"
                     /locus_tag="VW883_001860"
     CDS             4276..4755
                     /gene="rimP"
                     /locus_tag="VW883_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0274943.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLTFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            4799..5935
                     /gene="nusA"
                     /locus_tag="VW883_001861"
     CDS             4799..5935
                     /gene="nusA"
                     /locus_tag="VW883_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0274944.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            5957..6250
                     /locus_tag="VW883_001862"
     CDS             5957..6250
                     /locus_tag="VW883_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0274945.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6243..6542
                     /locus_tag="VW883_001863"
     CDS             6243..6542
                     /locus_tag="VW883_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0274946.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6559..9351
                     /gene="infB"
                     /locus_tag="VW883_001864"
     CDS             6559..9351
                     /gene="infB"
                     /locus_tag="VW883_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0274947.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9602..9952
                     /gene="rbfA"
                     /locus_tag="VW883_001865"
     CDS             9602..9952
                     /gene="rbfA"
                     /locus_tag="VW883_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0274948.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3072 a         1862 c         2303 g         2882 t
ORIGIN      
        1 agtgtcagta gataattttt ttagagactt aaccccgtta ctgttcattt taaatattat
       61 tggcctgtct tgcttttcag tgctaacata cattaacata aaagagatac tcttaaatat
      121 aagtaaatga tgatttggtt agtcctagaa ccaatcaatt tatgtttatc ggcttggcag
      181 attttatgtt tgtcatttgt ttgtatagag gtatttcaga aacagaattc tatcaacaac
      241 taatcgctta tataggtgta ttctctgctt gtttatcacg cttctgctca tgtggggctt
      301 gaagtattat aaaaagtagc tttctatcct tttctgacag gatatttgag tagaaggctc
      361 tattaaattg ttagtgaaat aaatgaatgg aggtatttaa tatgaaatac agattatttt
      421 ttgttatttt cttgagtagt gtgttggata ttcttttagg gacattttta caaatctcta
      481 tcgtatctat tgggtggctt gttctttaca gtggtttgtt tgaagcagga gttttccttc
      541 ttgctaataa aggggtggcg gtaaaaatca aggaagtaga tattcgaaat cgctttaaat
      601 ttatttttgg aaaaacctta tggtttcaaa ttcttttgct catctttttg ataatcaaac
      661 tttatcttgg tttggatgcg aggttgattt tattctatgg acatattttc attgtcttta
      721 atgccttaat gtatctatta tctagtagtc aggttagcct taaaaaaaac aaactgtctt
      781 cttaatctta cagcagtaga gcctgacaag gtgaggtcat agtagggagg atttctatga
      841 aaaagtatca acttctattc aaaataagtg cagtcttctc ttacttattt ttcgtatttg
      901 gtctttctca gctgacgctt atcgtccaaa actattggca attttcttct cagataggca
      961 atttattctg gattcaaaat atcttgagtt tactttttat tggagtcatg attgtggttc
     1021 ttgttaagac aggccatggt tatctcttcc gcattccaag aaaaaaatgg ctttggtatt
     1081 cgattttgac agtattagtg gtagtgttcc agatctcttt taacgttcag acagctaaac
     1141 atgttcagtc aactgcggaa ggttgggctg tattgattgg ttatagtggg actaactttg
     1201 cagagctagg tatttatata gccctgttct ttctggttcc actgatggaa gaattgattt
     1261 atagaggatt actgcaacat gctttcttta agcattcgcg atttggcctt gatttgcttc
     1321 ttccttccat tttgtttgct cttcctcatt ttttgagtct gcctagtctg ttagatatct
     1381 tcgtctttgc aacatttgga atcatctttg ccggtttgac ccgctatacc aagagtattt
     1441 atccatccta tgcggtgcat gtgatcaata atattgtagc gaccttcccg tttttgctca
     1501 cttttctaca tagggtcttg gggtaaaaaa acaaaaggct tgcttttcag ccatagagga
     1561 ggtcatcatg tataaacact tatttttcct agattccaaa actttagatc ggttgacacc
     1621 ctatattcta gtcttggctt ctgacaccat tgcttttaat gtttttgtgc taacctttgt
     1681 atctgcggtg gtttttaatt tcctaaattc catgctagct ttaatggcta tattcatagg
     1741 ggctggctat gtggtcggat tttggttact aatactcaat gaaaatcaaa gagcaaacta
     1801 ggaaactagc cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg gtttgaattt
     1861 gattttcgaa gagtataaaa tggtttgttt tggaaaggct agaactaaag aatgacgtgt
     1921 aggaagtctg tttgttgagg aggataattt tatggagttt tttgataaat ttcatgcctt
     1981 gtgttttgga tttttagtac taataattgt cattacagtt ccttatacga ttaaccatgg
     2041 ggattttttt caaaatgaat ctgcattgat tattgtaagt cttcttgtaa cctcgctgag
     2101 tgttgcttat gctagaaagt ttgaaatgat ttcttttggg atgttaagca agaaacaact
     2161 tttgcttttc attgcaatct ttcttctaag tgtacttgag acgctggttt atattcattt
     2221 cttcgctgtt tcttctggct caggggtcca acacttggcg gaagtcagca gaggaatttc
     2281 cctgtctttg attttgacta cctcagtttt tggccccatc caggaggaac tcattttcag
     2341 aggacttctt caaggtgcgg tttttgacaa ttcttggtta gggcttgtgc taacttcctc
     2401 tctcttttct ttcatgtatg gaccttctaa tgtcccttcg tttatttttt atctacttgg
     2461 gggcttgttg ctgggccttg cttataaaaa gagccaaaac ctatgggttt ctactctagt
     2521 ccacatgttt tacaacagtt ggccactcct atattattta taaaaattat gaaaaggtaa
     2581 gcagaagacg gtgcttacct ttttcaagct ataatgatac ccaagccaat ccagaggctt
     2641 ttctttgaga atcgggttag agtggttgac gaataggcca aaaactagta gaatagtaag
     2701 gaaactttat acggaggaaa gaaatggatt tgggtgataa tgagctaaca ctgactccca
     2761 tacctgggaa aagtggcaag gcttatatgg gtagctatcc tgatgggaag cgcatctttg
     2821 taaaaatgaa cacctctcca atcctacctg gtctagctag agaacaaatt gctccacaat
     2881 tattatggag tcgtcgtttg gcagatgggc gtgatatgtg tgctcaagaa tggttgacag
     2941 gcaagatatt gaccccctat gatatgaatc gtaagcaaat cgtcaatatt ttaacccgtc
     3001 ttcatcgctc acgtccgttg atgacacaat tgagtcgttt gggctatgcc atggaaacac
     3061 ctgtagattt actacagtct tggcaagaaa cggctccaga tgctttgcgt aaaaatcatt
     3121 ttatcagtga agtgatggct gatttgcgtc agactattcc aggatttaga gaggaccatg
     3181 cgaccattgt ccatggagat gtacgacata gtaattggat tgagacagat agtggcttga
     3241 tttatttagt agattgggat tcggttcgct tgaccgatcg catgtttgat gtggcccata
     3301 tgctctgcca ttatatttca gaacatcagt ggaaggaatg gttgacctac tacggttaca
     3361 agtacaatca aacggtatta agtaaattgt attggtatgg tcaattgtct tatttgagtc
     3421 agatttccaa gtattatatg aaccaagatt tagaaaatgt caatcgggag attcatggtt
     3481 tgcgtcattt ccgagacaag tatggaaaga gaagatgaga gttagaaatc gtaaaggggc
     3541 aacagaatta ctagaggcaa atccccagta tgtggtcctc aatcccttgg aagccaaggc
     3601 aaaatggcgg gacttgtttg gcaatgataa tcccattcat gtggaagttg gaagtggaaa
     3661 gggtgccttt gtttcaggta tggccaagca aaaccctgac atcaactata tcgggattga
     3721 tattcaaaaa tctgttttga gctacgcttt ggacaaggtg cttgaagttg gagtgcctaa
     3781 catcaagctc ttgtgggtag atggttctga cttgactgac tactttgaag acggtgagat
     3841 tgatcgcttg tatctgaact tttcagatcc atggccgaaa aaacgccatg aaaagcgtcg
     3901 tttgacctac aagacctttt tggacacctt caaacgtatc ttgcctgaaa atggagaaat
     3961 tcatttcaag acggataacc gtggcttgtt tgagtacagt ttagtgagct tttctcaata
     4021 tggcatgaaa ctcaatggtg tctggctaga tttgcatgcc agtgattttg aaggcaatgt
     4081 catgacagaa tacgagcaaa aattctcaaa caaggggcaa gttatctacc gagttgaggc
     4141 agaattttaa gagatagcct aaaattaggc tgtacaagtg cttttgcttt acataagttg
     4201 gcaaacgtgc tatactgata gtaagaatat gaaaagtgag gcggggaaat atcttcgcct
     4261 cttgcttatg aggaggtgga cgcaatcgca acaatcgtag aattagtcag agaagttgta
     4321 gaacctgtca tagaagctcc ttttgaactc gtggatatcg agtatggaaa gattggcagt
     4381 gacatgattc tcagtatttt tgtagataaa cccgaaggaa ttaccttgaa cgacacggca
     4441 gacttgacag aaattatcag tcctgtccta gacaccatca agccagatcc cttcccagaa
     4501 caatatttcc tagaaattac cagtccaggc ttggaacgtc ctttgaaaac caaggatgcc
     4561 gtcgctggag cggttggaaa atacatccat gtcggactct accaagccat cgataagcaa
     4621 aaggtctttg aaggaacttt gttgaccttc gaagaggacg agttgactat ggaatatatg
     4681 gacaagacgc gtaagaaaac cgtccgaatt ccatacagtt tagtatcaaa agcacgttta
     4741 gcagttaaat tatagaaaaa gaaaggatag cttttgagga ttcaaaagtg aagaaaacat
     4801 gagtaaagaa atgctagagg ccttccgcat tttggaagaa gacaagggaa tcaaaaaaga
     4861 agatatcatc gacgcagtag tagagtcgct tcgttccgct tatcgcagac gctatggtca
     4921 gtcagacagc gtagctattg acttcaacga aaaaacaggt gactttacag tttatactgt
     4981 ccgtgaagtt gttgatgaag tatttgatag ccgtttggaa atcagcttga aagatgctct
     5041 tgccattaat tcagcttatg aacttggaga caaaatcaag tttgaagaag caccagctga
     5101 gtttggtcgt gtagcagccc aatctgccaa acaaaccatc atggaaaaaa tgcgcaagca
     5161 aacacgtgcc atcacttaca atacttacaa agaacatgag caagaaatca tgtctggtac
     5221 agtagaacgc tttgacaacc gctttatcta tgtcaacctt ggtagcatcg aagcccaatt
     5281 gtcaaaacaa gaccaaattc ctggagaagt ttttgcttct catgatcgta tcgaagttta
     5341 tgtttacaag gttgaagaca accctcgtgg tgtgaacgtc tttgttagcc gtagccatcc
     5401 agaaatgatc aaacgtttga tggagcaaga aattccagaa gtttatgatg gaactgttga
     5461 aatcatgagc gtggctcgtg aagcaggtga ccgtacgaag gttgctgttc gtagccacaa
     5521 tccaaacgtg gatgctatcg gtacaatcgt tggacgtggt ggtgctaata tcaagaagat
     5581 tactagcaaa ttccacccag ctcgttacga tgctaaaaat gaccgcatgg taccaatcga
     5641 agaaaatatc gatgttatcg agtgggtagc agatccagct gaatttatct acaatgccat
     5701 cgctcctgct gaggttgacc aagttatctt tgatgaaaac gacagcaaac gtgccttggt
     5761 ggttgttcca gataacaagc tttctcttgc cattggtcgt cgtggacaaa acgtgcgctt
     5821 ggcggctcac ttgactggtt accgtatcga tatcaagtct gctagcgaat ttgaagccat
     5881 ggaagacgct gcttcagtag agttggaagt agaaaacgat actgtagaag aataaaagct
     5941 gctagaggag ggaaagatga aaacaagaaa aatccctttg cgcaagtctg ttgtgtctaa
     6001 cgaagtgatt gataagcgtg atttgctccg cattgtcaag aacaaggaag gacaagtctt
     6061 tattgatcct acgggcaagg ccaatggccg cggcgcttat atcaaactag acaatgcaga
     6121 agccctagag gcgaaaaaga agaaggtctt taaccgcagc tttagcatgg aagtggaaga
     6181 aagcttttat gacgagttga tcgcttatgt ggatcacaaa gtgaaaagaa gagagttggg
     6241 acttgaataa gcaaaagata agtaatctct tggggcttgc tcagcgagca gggcgcatca
     6301 tatcgggtga agaattggtg gtcaaggcca ttcaagacgg caaggccaag ttggtctttc
     6361 tagctcatga tgctggaccc aatctggcca agaagattca agataaaagt cattattatc
     6421 aagtagaaat tgtaaccgtg ttttcaacac tggaattaag catagcagtc gggaaatcga
     6481 gaaaggtttt ggctgtaaca gatgctggat ttacaaagaa aatgaggtct cttatggaat
     6541 agaagaggag gacatgattt gtctaagaaa agattgtacg aaatcgcaaa agaacttgga
     6601 aaagaaagta aagaagttgt agcgcgtgca aaagagttgg gcttggatgt gaaaagccac
     6661 tcatcaagtg tggaagaagc tgtcgctgca aaaattgctg ccagctttaa gcctgcagct
     6721 gctccgaaag tagaagcaaa acctgcagca ccaaaagtaa gtgcagaaaa gaaaaccgaa
     6781 aaatctgagc cagctaaacc agctgtagct aaggaagagg caaaaccggc tgagccagtt
     6841 gctccgaaaa cagaaaaagt agcagcgaaa ccgcaaagcc gtaatttcaa ggctgagcgt
     6901 gaagcccgtg ctaaagagca ggcagaacga cgcaagcaaa ataagggcaa taaccgtgac
     6961 caacaacaaa acggaaaccg tcagaaaaac gatggccgta atggtggaaa acaaggtcaa
     7021 agcaaccgcg acaatcgtcg ctttaatgac caagctaaga agcagcaagg tcagcaaaaa
     7081 cgtagaaatg agcgccgtca gcaagaggac aaacgttcaa atcaagcggc tccacgtatt
     7141 gactttaaag cccgtgcagc agccctaaaa gcagagcaaa atgcagagta cgctcgttca
     7201 agtgaggaac gcttcaagca gtatcaggct gctaaagaag ccttggctca agctaacaaa
     7261 cgcaaggaac cagaggaaat ctttgaagaa gcggctaagt tagctgaaca agcacagcaa
     7321 gttcaagcag tggttgaagt cgtccctgag aaaaaagaac ctgcagtgga tacacgtcgt
     7381 aaaaaacaag ctcgaccaga caaaaatcgt gacgattatg atcatgaaga agatggtcct
     7441 agaaaacaac aaaagaatcg aagtagtcaa aatcaagtga gaaatcaaaa gaatagtaac
     7501 tggaataaca acaaaaagaa caaaaaaggc aataacaaga acaaccgtaa tcagactcca
     7561 aaacctgtta cggagcgtaa attccatgaa ttgccaacag aatttgaata tacagatggt
     7621 atgaccgttg cggaaatcgc aaaacgtatc aaacgtgaac cagctgaaat cgttaagaaa
     7681 cttttcatga tgggtgtcat ggccacacaa aaccaatcct tagatgggga aacaattgaa
     7741 ctcctcatgg tggattacgg tatcgaagcc aaacaaaagg ttgaagtgga taatgctgac
     7801 atcgaacgtt tctttgtcga agatggttat ctcaatgaag atgaattggt tgagcgtcca
     7861 ccagttgtta ctatcatggg acatgttgac cacggtaaaa caaccctttt ggatactctt
     7921 cgtaactcac gtgttgcgac aggtgaagca ggtggtatta ctcagcatat cggtgcctac
     7981 caaatcgtgg aaaatggtaa gaagattacc ttccttgata caccaggaca cgcggccttt
     8041 acatcaatgc gtgcgcgtgg tgcttctgtt accgatatta cgatcttggt cgtagcggca
     8101 gatgacgggg ttatgcctca gactattgaa gccatcaacc actcaaaagc agctaacgtt
     8161 ccaatcatcg tagccattaa caagattgat aaaccaggtg ctaacccaga acgcgttatc
     8221 ggtgaattgg cagagcatgg tgtgatgtca accgcttggg gtggagattc tgaatttgtt
     8281 gaaatctcag ctaaattcaa ccaaaatatc gaagaattgt tggaaacagt ccttcttgta
     8341 gctgaaatcc aagaactcaa ggcagaccca acagtgcgtg caatcggtac ggttatcgaa
     8401 gcgcgcttgg ataaaggaaa aggtgcggtc gcaacccttc ttgtacaaca aggtaccttg
     8461 aatgttcaag acccaatcgt tgtcggaaat accttcggtc gtgtccgtgc tatgaccaac
     8521 gaccttggtc gtcgtgttaa agttgctgga ccatcaacac cagtctctat cacaggtttg
     8581 aacgaagcac cgatggcggg tgaccacttt gccgtttacg aggatgaaaa atctgcgcgt
     8641 gcagcaggtg aagagcgtgc caaacgtgcc ctcatgaaac aacgtcaagc tacccaacgt
     8701 gttagccttg aaaacctctt tgataccctt aaagctgggg aactcaaatc tgttaatgtt
     8761 atcatcaagg ctgatgtaca aggttctgtt gaagcccttt ctgcctcact tcaaaagatt
     8821 gacgtggaag gtgtcaaagt gactatcgtc cactcagcgg tcggtgctat caacgaatca
     8881 gacgtgaccc ttgccgaagc ttcaaatgcc tttatcgttg gtttcaacgt acgccctaca
     8941 ccacaagctc gtcaacaagc agaagctgac gatgtggaaa tccgtcttca cagcattatc
     9001 tacaaggtta tcgaagagat ggaagaagct atgaaaggga tgcttgatcc agaatttgaa
     9061 gaaaaagtta ttggtgaagc ggttatccgt gaaaccttca aggtgtctaa agtgggaact
     9121 atcggtggat ttatggttat caacggtaag gttgcccgtg actctaaagt ccgtgttatc
     9181 cgtgatggtg tcgttatcta tgatggtgaa ctcgcaagct tgaaacacta taaagacgac
     9241 gttaaggaag ttacaaacgg ccgtgaaggt ggattgatga tcgacggcta caatgatatt
     9301 aagatggatg atgtgattga ggcgtatgtc atggaagaaa tcaagagata agattttttg
     9361 ctcctttctt aggtggtgag ggacgcaagc aaaccgatgg tttcattgct tatttttgag
     9421 cctagggtct caaaaatccc ctgtgatggg actgataaat cagttccatc actttcacca
     9481 cggcgaaaga agcagatgac ttcaaattga acttcgtttc aatttaaact gaaaatcaag
     9541 aagtttaaaa tagctaggtc tgctggccta gcttttggtt caaagtagag aaaggaatat
     9601 catggcaaat catttccgta cagatcgtgt gggcatggaa atcaagcgtg aagtcaatga
     9661 gattttgcaa aagaaagtcc gtgatccacg tgtccaaggt gtgaccatca cagatgttca
     9721 gatgttgggt gacttgtctg ttgccaaggt ttattacacc attttgagta accttgcttc
     9781 ggataaccaa aaagcccaaa tcgggcttga aaaagcaact ggtaccatca aacgtgaact
     9841 tggtcgcaat ttgaaattgt acaaaatccc agatttgacc ttcgtcaaag acgagtccat
     9901 cgagtatgga aacaagattg acgagatgct acgcaatctg gataagaact aaagaagagg
     9961 ggttgcccct cttttttggt ggaggaaaat aggttgaatt tgaaatggaa aaatattctt
    10021 ttaaaatata ttgaaactag aatagtacgc ctctacttct aaaacattgt tagaaatcga
    10081 tttgactgtc ctgatcgatt tgtcctgttc ttgtttcat
//
LOCUS       DAVKXA010000062         9883 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKXA010000062 DAVKXA010000000
VERSION     DAVKXA010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9883
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.062"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(8..166)
                     /locus_tag="VW883_001866"
     CDS             complement(8..166)
                     /locus_tag="VW883_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0274949.1"
                     /translation="MSLLETAKRHQLNSEKYLFYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(237..683)
                     /locus_tag="VW883_001867"
                     /pseudo
     CDS             complement(237..683)
                     /locus_tag="VW883_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(759..1193)
                     /locus_tag="VW883_001868"
     CDS             complement(759..1193)
                     /locus_tag="VW883_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0274950.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHIIHQKINLKVPNYRQEEDWARMDL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(1269..2120)
                     /gene="rfbD"
                     /locus_tag="VW883_001869"
     CDS             complement(1269..2120)
                     /gene="rfbD"
                     /locus_tag="VW883_001869"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0274951.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            complement(2186..3235)
                     /gene="rfbB"
                     /locus_tag="VW883_001870"
     CDS             complement(2186..3235)
                     /gene="rfbB"
                     /locus_tag="VW883_001870"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0274952.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(3232..3840)
                     /locus_tag="VW883_001871"
     CDS             complement(3232..3840)
                     /locus_tag="VW883_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0274953.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKNHPLLKDVKPLKKKICKKERI"
     gene            complement(3841..4710)
                     /gene="rfbA"
                     /locus_tag="VW883_001872"
     CDS             complement(3841..4710)
                     /gene="rfbA"
                     /locus_tag="VW883_001872"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0274954.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            complement(4870..5703)
                     /locus_tag="VW883_001873"
     CDS             complement(4870..5703)
                     /locus_tag="VW883_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEV0274955.1"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQDSIKPTYTFKNVKEMWKGI
                     V"
     gene            complement(5718..6422)
                     /locus_tag="VW883_001874"
     CDS             complement(5718..6422)
                     /locus_tag="VW883_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEV0274956.1"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     gene            complement(6438..7466)
                     /locus_tag="VW883_001875"
     CDS             complement(6438..7466)
                     /locus_tag="VW883_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0274957.1"
                     /translation="MKNNDLKIGSGAIHQISATLSQNSISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     gene            complement(7502..8650)
                     /locus_tag="VW883_001876"
     CDS             complement(7502..8650)
                     /locus_tag="VW883_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HEV0274958.1"
                     /translation="MNILQYIKILARTIFMLLISTVLLPVRLKNNKILFINFNGKGYG
                     DNPKSICEYLRTTYPDLDLVWLARDNEGFPDGVRVVKYGTFQAFYEQASSKVWVYNVR
                     AFARILKKRGQIYIQTWHGASSFKLIEKQADLPINYVLEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKELSIHSDDYVILYAPTFRD
                     DGDASYLDINFERLLQCVEHGIKKKCKFLIRLHPNHSHLCNNISFNKNIINATFYSDM
                     QELTLLADVLVTDYSSSIFDFMLLNKPYVRYVNDLEKYAELRGVSDTYYELPDSIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     gene            complement(8653..9843)
                     /locus_tag="VW883_001877"
     CDS             complement(8653..9843)
                     /locus_tag="VW883_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEV0274959.1"
                     /translation="MRFLMKEDVSKKSVFSIAILDIFLGSIIFCLLLLVNQIFSLSEL
                     ISQYSIYIMAIFAFYTLNNFLIQYSKGIDKIGVTAISGVISAAVMLSMNILLLVVLNW
                     GLLGFFIANICGYVIPCVYIIVKLKLWDLFELKIDRSLQWEMIYYTLPLILNTLSWWV
                     NNTSDRYIITVIIGIQASAIISVAYKIPQIFSTISAIFIQSWQISAIKIQEEKEGNTF
                     ISKMLLYYNALLLIIASGIILFVKPISNILFGASFYSAWTLVPFLIISSLFNAISGYI
                     GAIMGAKMDTKNIAKSALVGMIANVFLNIVLTFLMGLQGITISTMIASFLIFYMRKDS
                     VEEIAPETYRAIYLSWFLLVVEASLLVYIDFIIGATLVTLINLFLLKDTLKPLCLKLL
                     KGFK"
BASE COUNT         3118 a         2078 c         1507 g         3180 t
ORIGIN      
        1 agatttctta tttgcacttt tcttgtacaa ctttagtcca tggtaaataa gcctctaaaa
       61 cctctttgtt tacgagagtt tcctcgtttg gaagacattc tagaagatag aatagatatt
      121 tctcgctatt taattgatga cgtttagctg tttccaacaa actcataata atagctgttg
      181 ctttagctcc ttcaaaactt tgagaaaata accaccctcg ctttttaaaa tttagcttag
      241 gctaaaagag tccactgaac tcttttactc cgtcccataa ccaatgattt aatggcgcgt
      301 tcagctagat tattggaaag gaccagatgt ccgtctttca aaatagtctt aaaggtttct
      361 tcatacttga ggctgtattc aattgccctt cctagttttg aacctgctaa aactgactga
      421 cgccggcact aagcaaagaa gtcttccatt aggggttgga gctcttcttg acgtttctgt
      481 agtcgttcat cagctggcaa agcctcccag tctctttcca gggaaaataa ctgatcacaa
      541 taagctaaac ctttagcttc taaggatgat ttatctgctt gcttgggggt cgcttcaaaa
      601 aacttccttc tcacatgtgc ccaacatcca acaagttcag cttcttccag ttgacgataa
      661 gcttctagcg gttcgcagtt taccaagctt agcgtcgcct tgctcctaaa ccttggactg
      721 ctatcgcata ggcagaacta gaggactaaa gtcctaagtt actgccgcaa catatcacaa
      781 tgcacatagc cagaataatc tcctaggaat tcttgtacta ctaaaccact ccgacgctga
      841 tcatgatggt acagcgtgat tgcttgattc tcagctttcc cagacaaaaa ggtccaatag
      901 taggtcagat ggctatcact ctctagaacc cgataagagg tttcatccgc atgaagaaga
      961 ggttgttcta acaacttttc tcgtaaaagg ttataaaggg actctaaata gtattgactt
     1021 gccttgatat gccaattaga gatttcctta cgtgtgattg gtaaatccat cctagcccaa
     1081 tcttcttctt ggcgataatt gggtaccttc agattaatct tctgatggat gatgtgagcg
     1141 ataatagaaa ctgagccaaa gctatgcgcc aaagagacca gcaccaacaa caagataatc
     1201 gtacatctta agctcctttg gagttcatta tctgcctctt ttattagact agaaaatcat
     1261 tctactactt atctcacttc ttgtttgtaa aattcttgca atgcatcttg ccaagttgga
     1321 ataacaaatc cagtagcttt ggctttggcc aggctcatcg ttgagtttag cggacgttta
     1381 gctttggctg gaaattgact ggaatctact ggcttgactt cgacatctgt atctttcaaa
     1441 atttcaactg caaaatcata ccatgttgtg tcttctgtcg catcatttga caaatgataa
     1501 taaccaaatt ccttacgatt ttcagctagg taggtcatga actcagccaa ggtacgagtc
     1561 caagtcggac gaccgtactg gtcatttaca actgttaaag tcttatgagt tttcgcaaga
     1621 ttttgcatgg taaaaacgaa gtttttgcca taatttccaa atacccaggc agtacggata
     1681 atatagaaat tagacacatg cttctcaact aactcttccc ccatacgctt agtgcgtcca
     1741 tattctgtct gtggatctgg tcggtcatca acttcccact cttgtccaac tggtttctta
     1801 ccgtcaaaga catagtccgt agaaatataa actagagttg caccatgctt ttcagatgct
     1861 tttgcgacat tttttgtccc cgtcacattg atggcgaagt ccaactcttt tccttcatcc
     1921 tctgctgcat caacagcggt gtaggctgca cagtggtaga ctaaagtcgg tttcacctct
     1981 tcaaaaactt tttcaaccat ttcttcattg gtaatgtcca tctcagccac atctactgcc
     2041 acgtattctt cattacgttc atccaataaa tagcgaagtt ccgttcctaa ttggccattt
     2101 gcccctgtaa ttaaaatcat ctctagacct ttctaatatg taactcttcc caatatagca
     2161 ataaaaagca gctatttcct gctttttata ctgtaataat ctcctgagtc ttagcataat
     2221 tggcttcaac agcttctttt tctgctttcc accattcttg gttatctgta taccacttga
     2281 ttgttgcctt gagcccagct tcaaagttgg taaattcagg tttccacccc aactcatcac
     2341 ggagcttgct ggcatcaatc gcatagcgaa ggtcatgtcc tgcacggtca gtcacatgat
     2401 cataggcatc cgtagcttgt cccatttcct taaggataag ttccaaaact tccttattgt
     2461 tcttctcacc atcagcccca atcaagtagg tttcaccgat ttgccctttt gtcaagattg
     2521 tccaaactcc tgaagaatgg tcattggtat gaatccagtc acgaacattc ttaccttcac
     2581 cgtaaagttt tggcttaatt ccacttagga tgttagtaat ctgacgtggg atgaattttt
     2641 cgatatgttg ataaggaccg tagttatttg aacagttgga aatcgttgcc ttgactccaa
     2701 aagaacgcac ccaggctttg acaatcaaat ctgaggctgc cttggttgat gagtacggag
     2761 agcttgggtt gtattttgtt tcagcagtaa atttctcacc tggtccttca ccatgacctg
     2821 gcaaatcttc gcgtaaaggg agatccccat aaacttcatc tgtcgataca tggtggaagc
     2881 gaatatcata cttacgagca gcttctaaaa gagtataggt tccgatgaag ttagtatgaa
     2941 taaatggcga tggatcattg agcgaattat cattgtggct ttccgctgca taatgaacga
     3001 tagcatctgc ttgagcagcc aacttgtcta ccaactccgc atcagcaatg tcaccaacaa
     3061 ctaactcaac acgattacct aaaatttcct caatattcgc gcgatttcca gcataagtca
     3121 acttatctag gactgtcacg tgaacacctg gaaagttctc gtaaacataa tggacaaagt
     3181 tagaaccgat aaagccagct ccacctgtca cgataatatt tttgtattca gtcatattct
     3241 ttccttttta caaatcttct ttttcaaagg ttttacatcc ttaagtagtg gatgattttt
     3301 atctgcttct gaaacttctg cttctgcaat attttcccat tcaataccaa ggcttggatc
     3361 agcgtagttc acaaaggcat acttgggttt gagttcaaga gcccagtaat cattgaccag
     3421 atagctatat gacactgtat ctgataaaac ttggaagcca ttagctacgc ctcgaggaac
     3481 aaagattccc ttactcgcat caatcactgt ctgataggta ttcccaaagg tttcaccctc
     3541 gcgtagatca acccaagaac ccagaacttt ccctccatct gctacagaga tgtacttatc
     3601 ccaaggctct gcgtggaggc ctcgaaggac atttttacgt gagaaggata cattgttttg
     3661 caattttcct tctgcaaaga aagactctgg aaatccaagt ggaagcattt tttccttttg
     3721 gaaattttct ttaaaccagc cacgattatc tccatgaacg gggatatcaa actccaacat
     3781 gcctggaata gcttcaacct tgcgtgccgc aagcgtctta ccgaaaaaat tatctgtcat
     3841 ctatgcttct ccaatcaaac ggagtagata ctgtccgtat tcatttttct taagtggttg
     3901 ggctaaggcc aacacatctt cgcgactgat atagcccata cggtaagcaa tttcttccaa
     3961 gtttgctacc tgaacatttt gcatccgttg gactgtttcg atgtactgcg aagcctctag
     4021 taaactttca tgagtgccag tatccaacca agcaaaacca cgtcccatga gctcaacaga
     4081 caaatcacca cgatccaagt aagccttgtt gacatctgta atttccaatt caccacgagg
     4141 acttggttta atacttttgg caatctctac tacatcatta tcatagaaat agagtcctgt
     4201 cactgcatag tttgaacgag ggtattctgg cttttcttcg atggagatag cattcatatt
     4261 ttcatcaaat tctacaacac caaagcgttc tggatccttg acatggtagc caaaaacagt
     4321 cgcacctttc tctttcttgg ctgctttttg aagcattgtg ctcagaccag gaccatggta
     4381 gatattgtca cctaaaatca aggcaacgct atcgtcaccg ataaactctt ccccaatgat
     4441 aaaggcttgt gccaaaccat ctggacttgg ttgctcagca taagaaagtt taataccaaa
     4501 ctcagaacca tcttgaagaa gctctttaaa acgaggcaaa tcttgaggag ttgagataat
     4561 caaaatatcc ctaatcccag ccaacattaa tgttgaaagt gggtagtaaa tcatcggttt
     4621 atcataaacc ggcataagtt gttttgatgc agcgcgagtc aaaggataca agcgagttcc
     4681 cgaaccacct gctagaataa tacctttcat aaaaggggta cctttctttg ttgatgagta
     4741 ctttacgttc acgaacgatt tggggagaaa aataatttta atttgtccat tattaaaata
     4801 ataaaatcaa tttaaataca tacgagtatt ttgacagtat tcatgaattc actattcaga
     4861 atgaaaaaat cagacaattc ctttccacat ttctttcacg tttttaaatg tataagtcgg
     4921 ttttatacta tcttgttgaa tatcattcac cgttgcttct cctgtcagca cacaaactga
     4981 agttactcct gcatttatac cagtcatgat atccgtatac aagcgatctc caatcacaac
     5041 tgtttcaaat agagaataat ttaatttttt tcgaacaata tcaaccatcg taggttcagg
     5101 tttacctatg taaacaggtt tcctatcgac tgatttacta atcatatcac aaatagaacc
     5161 acaatccggg atgaatccaa acgatactgg gcagcgaata tcagggttag tagctatgaa
     5221 aggtacgtcc tttgttgata gaatctcgca ggtattgcga attttatcac tggttaattc
     5281 tgtatcaaaa ccaacaagaa caacatctat atcagcacta acttgctcag ttacatcaat
     5341 tcctgcgtca gatagttctt ttatcaaaga ttttgttcct tggcaataaa ctttagattt
     5401 aggataattt tctttaatat aaacaattgt ggcttgagca gaggtaaaaa aattatctcg
     5461 ttcagcttta atacctaatc tgttaacttt ttcaacatag tcaacaacag acttagatga
     5521 attgtttgta ataaaaatat actcaccgcc aatattatga atatagtcta ataattcgag
     5581 agtaccctca aacaacctat cttcttcata aatggtacca tccatatcaa ataagaataa
     5641 ttttttattc tgaagttcac taatatcagc accaaaataa tcaactctat ttgtcaattt
     5701 cattctccgt attcggttca agcaaatagt ttttctgcag caactaagtc ttcatgatta
     5761 tcaatttcta accaacgacc ctctaatgga catgctacaa attcaacttc agaaagaatt
     5821 gcattaagag caacctcact ccacatttga agttctcgtt tatcttcaat aaattcctta
     5881 cacttttcaa agaatcgagc acctgcttca taagagaatt tataaacatc aatagaagct
     5941 cctaaagttt cctcaggtga aatctgttta gaaatttcta ctaaacgacc atttttttct
     6001 acgactttca tagactcttc aatataaata cctaaatcag ttacaattgc atttggagct
     6061 ttatgaagca acagactttt aataacagaa gcatcataaa atacatctgc attcatcatt
     6121 aagaagtcac tatcacccat tgcagctttt cctagatagg ctgaatacat attattagtc
     6181 gttttaaaat caacattatc aataatatta atttctggat acttttcagt aactgcatct
     6241 gttaatacag atgacttata tccagcaata atcgtaatat ctgtaatatt attttgatat
     6301 aaattttcaa tttgtttcat caaaattggc ttaccattga ctggtaccaa agattttggt
     6361 acctcattgg taattggagc tagacgtgtt cctaaccctg ctgctaaaat aagtgctttc
     6421 attttttcct ctcttctcta caactcgctt atgagttcct tatatatttg tttcaatcta
     6481 tctgtgctaa gatcaacttc atgcagatag gtatagcgat tacttctcat ttttgtagca
     6541 tgttgcatac aataaataaa caactcttca tctatcccca aaagtttcgg gttaatatga
     6601 acctcaaatc tttgcaagta atccactaca gtatcaacag aattttcaat taatttcaaa
     6661 actgcgactg tacctaatgc aacctgaatt ccatgaagat tccttgtaga accatagtaa
     6721 tctaatgcat gactaaataa gtgctctgac ccactgacag gtctactact tcccgcaaaa
     6781 tccattgcaa tgcctgataa aactaaagag tttaccaaaa cttcaataaa atcaggggta
     6841 atagaattat acttcgtttt cattaaagca tctaaagaat tttgcgacat tagatatgca
     6901 aaaccatgca tctcatcttt ccctcgctca actgccaact cccaatcttt caatgcagtg
     6961 taattggata ttgtatcacc gataccagct tttatatttt gtataggtcc tgatgcaata
     7021 acatcaatat caattagtgt cattgagggg atagccgccc ctaagctttt tggtctatca
     7081 tcctgccttt tcaaaacagc aactggggaa gcaatgccat catttgctgc tgttgtcgga
     7141 atcgataggt aaggacgttt cgaaataaaa gatgcatact tgcagacatc taaaacacga
     7201 cctcctccca ttcccacaat acagtcaata tctgtggcaa tagcccgttc tgctatattc
     7261 atcgcataag caatagtatt ataattgcaa ctttcttcct ttacccgacc aatttcctct
     7321 atttgtgaac gtactatcga accgtacaag tcatcgacaa ctggatcagc acaatataaa
     7381 atctttcccg aaatactatt ttgagaaagt gtagcggaaa tttgatgaat agctccactt
     7441 cctatcttta aatcattatt tttcaaatct cgttacctta aaaataaccc aatgttttac
     7501 ttcacaactc ttgaattatt ctccttccta cattttcact agcggttcca ttaaagattg
     7561 gacacagtat ttcatttcta tattttttta tagaatcata atcaaaattt tctatttttt
     7621 taggcagtaa gtcatacaat tcttcagcag ttttaataat cgaatccggc aattcgtaat
     7681 atgtatctga taccccccta agctcagcat atttttctaa atcattcaca tatctgacat
     7741 aaggcttgtt taaaagcata aaatcaaata tcgaggaaga ataatctgtg actaaaacat
     7801 ctgccaacaa agtaagctct tgcatatctg aataaaacgt agcattgatt atattcttat
     7861 taaatgaaat attattacac aaatgggagt gattagggtg taacctaatt aagaatttac
     7921 atttcttttt aattccgtgt tcaacacatt gcaaaagccg ttcaaaattt atatctaaat
     7981 aagatgcatc cccatcatct ctgaaagtag gggcatataa aataacataa tcatctgaat
     8041 gaatgcttag ttcttttctg atattattta acttgtcgta gtcttcctta tagtgaaaca
     8101 aggcatcatt tctcggcatc cccacctcaa aaatttctcc tgaataccaa aaatactttt
     8161 gaaattcttc agtttgtttt ctgctatctg aaatcattat atctgtgact cttgcatcat
     8221 acttagcttc taaaacataa tttattggta aatcagcttg tttttctatc aacttaaaac
     8281 tagaagcacc atgccaagtt tgaatataaa tctgtcctcg tttttttagt attcttgcaa
     8341 aagctcttac attatatacc caaaccttcg aactcgcttg ctcataaaaa gcttggaaag
     8401 tcccatattt aacaacccta accccatctg gaaaaccttc gttatctctt gcaagccaaa
     8461 ccaaatctaa atctgggtaa gtagttctaa gatactcaca aatactttta ggattatcac
     8521 cataaccctt cccattgaaa ttaataaata gaatcttatt attttttaac ctgacaggta
     8581 ataacactgt acttatcaat agcataaaaa tagttctagc caaaatttta atgtattgta
     8641 gaatattcat tttcatttaa atccttttaa taattttaaa cataatggtt taagagtatc
     8701 ctttaataaa aataaattga ttaatgtaac taatgtagcc ccaataataa aatctatata
     8761 aaccaaaaga ctagcctcaa ccactaacaa aaaccacgaa agataaatag ctctatatgt
     8821 ttctggagca atttcttcaa cactatcttt tctcatataa aaaataagaa aactagctat
     8881 catagttgag attgtaatcc cctgtagtcc cattaaaaat gttaatacaa tatttaaaaa
     8941 aacattagct atcattccaa ccaaagcaga tttagcaata tttttagtat ccattttagc
     9001 gcccattatc gctcctatat aacccgaaat cgcattaaac aaactgctaa taattaaaaa
     9061 cggtacaagc gtccacgctg aataaaatga agctccgaag agtatattag agattggttt
     9121 tacaaataga atgataccgc tcgctataat cagcaagagt gcattataat ataaaagcat
     9181 ttttgatata aaggtgttac cttctttttc ttcctgaatt tttattgcag atatttgcca
     9241 cgattgaatg aatatagcgc taattgtgga aaaaatttgt ggaatcttat aagcaactga
     9301 aataatcgca ctagcttgta tacctataat tactgttata atatacctat ctgaagtgtt
     9361 attaacccac caacttaaag tatttaaaat caaaggtaaa gtataatata tcatttccca
     9421 ctgtaacgat ctatcaattt taagttcaaa taaatcccat aattttagtt ttactattat
     9481 atatacacaa ggaatgacat acccacaaat atttgcgata aaaaaaccta gtagtcccca
     9541 atttaatacc actaacaata aaatattcat cgaaagcata actgctgcac ttatgactcc
     9601 agagatagcc gttacaccta ttttatcaat ccctttagag tattgtatca aaaaattatt
     9661 aagtgtataa aaagcaaaaa tcgccatgat atatatgcta tattgagaaa ttaactccga
     9721 taaagaaaat atttgattga ccagtagtaa caaacaaaaa ataatagacc ctaaaaatat
     9781 atcaagtatt gcaatcgaaa aaactgattt ttttgaaaca tcttctttca ttaaaaatct
     9841 cataactgct tcagatatat tcaatgtcag gattggtaca agg
//
LOCUS       DAVKXA010000063         9854 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKXA010000063 DAVKXA010000000
VERSION     DAVKXA010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.063"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(161..916)
                     /locus_tag="VW883_001878"
     CDS             complement(161..916)
                     /locus_tag="VW883_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0274960.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(986..3637)
                     /locus_tag="VW883_001879"
     CDS             complement(986..3637)
                     /locus_tag="VW883_001879"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0274961.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAIAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNIMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(3649..4611)
                     /locus_tag="VW883_001880"
     CDS             complement(3649..4611)
                     /locus_tag="VW883_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0274962.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDINFTYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(4613..5170)
                     /locus_tag="VW883_001881"
     CDS             complement(4613..5170)
                     /locus_tag="VW883_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0274963.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKVTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(5157..5606)
                     /locus_tag="VW883_001882"
     CDS             complement(5157..5606)
                     /locus_tag="VW883_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV0274964.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGGFIKKARKKDGKN"
     gene            complement(6018..6413)
                     /locus_tag="VW883_001883"
     CDS             complement(6018..6413)
                     /locus_tag="VW883_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0274965.1"
                     /translation="MSKKLNRKKQLRNGLRRSGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIDPATIKKLKENGIKFK"
     gene            complement(6509..6763)
                     /locus_tag="VW883_001884"
     CDS             complement(6509..6763)
                     /locus_tag="VW883_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0274966.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(6773..8107)
                     /locus_tag="VW883_001885"
     CDS             complement(6773..8107)
                     /locus_tag="VW883_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0274967.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWIQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8107..8340)
                     /locus_tag="VW883_001886"
     CDS             complement(8107..8340)
                     /locus_tag="VW883_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0274968.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            8371..8445
                     /locus_tag="VW883_001887"
                     /pseudo
     CDS             8371..8445
                     /locus_tag="VW883_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(8653..8793)
                     /locus_tag="VW883_001888"
     CDS             complement(8653..8793)
                     /locus_tag="VW883_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274969.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(8790..8972)
                     /locus_tag="VW883_001889"
     CDS             complement(8790..8972)
                     /locus_tag="VW883_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274970.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(8974..9753)
                     /locus_tag="VW883_001890"
     CDS             complement(8974..9753)
                     /locus_tag="VW883_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274971.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
BASE COUNT         2837 a         2210 c         1803 g         3004 t
ORIGIN      
        1 atgtaaataa taaaagagtt ataatcagca ctactgataa attcaatacc gatttcgcca
       61 tcttaaaact tagtcaaacg aataccgttg atttccagtt cattaagtcg ttgacctgtc
      121 aagacttctc gttccttcaa ctggaaaagt taagggggaa ctaatacaaa tcctctacgc
      181 ttctatattc aatgatttca tttttgataa tattcttttt aaactcaaaa tgttttaaag
      241 gattatcgat taacactaac tttggaatat catctagatt tgtgaccaag gataaaataa
      301 aatccgattg aaactccttg actttttcaa attcttttgc agttaaacgc acacgcccct
      361 tagattttcg gatacctttt acttcggcaa ggtaagaata ctcttggaca tctacctgaa
      421 agtcatatcc atcaccataa agacgggcat cggttaactg tccaccttgg aatttttctt
      481 ctttatcaaa atgaaggata aaataattct cagcctccat tcccgtttcc tgtagacgtt
      541 tgaatttagt tcgaactatt ggtttttcaa cgatggttat gcctgttttc ttcccttcac
      601 tggcaagtaa cattttaact atttcagcat aactatgaac atcttcattt ccaaacatca
      661 tatcaattaa atctttacga aaacgataaa cttcagcttt ctgccaccaa ccttttcgat
      721 tattgtcaaa ataaggatca aataaatcca ttctattttt tacaactcca gttgtttcag
      781 caattcccag agaaaccaca tagcgataaa actccgactt gctagagcat tgaaattctt
      841 ttataaaaag cttgtcaaac ttggcaagac cgtagccaat taaatttaac aattcataat
      901 gagggtgttt ggacatcact ttctccatca atagatattg atttcattat accaaaaaac
      961 acggctcatc accgtgtttc tgtgtttatt tcaccaactt cttcatctca tcaatacgtg
     1021 ctacggtcac atcatacttg gcttggtagt cggcttgttt gtctttttct ttttggacaa
     1081 cttctggttt agcgttggcg acgaagcgtt cgttgctgag ttttttgcca accatgtcga
     1141 gttctttctg ccatttggca agttcttttt ccagacgtgc caattcttct tcgacattca
     1201 agaggtctac cagtggcaag aagatttcgg ctcctgtaat aacgcttgac atagccagtt
     1261 caggtgcagg gatggttgat gcgatttcca agtgttctgg atttgtaaag cgtttgatgt
     1321 agttgacatt gctgttaaag aaggcttcca agtcactatc gctagtctta acaaggatgg
     1381 tgataggttt gcttggtgct acatttactt ccgcacgcgc attacgaacg gcacggatca
     1441 agtctttgag actttccaca ccagtgtggg cagcaaggtc ctcaaaggct gggttgacag
     1501 ttgggtatgc tgctgtcacg atagagcctt cagcgtactg accaaagatt tcttctgtca
     1561 cgaacggcat tattgagtga aggagacgaa ggattttatc cagcgtatag aggagaacag
     1621 atcgagtaat taccttatcg tcttcattgt cgctgtaaag aacttccttg gtcaactcaa
     1681 cataccagtt ggcaaattct tcccaaatga agttgtaaag gatatgacca gccacaccaa
     1741 actcgaactt atcaaagttt tcagtaactt ttgcaatggt ttcgttgaga ttgtggagaa
     1801 tccagcggtc cgtcacatta ccagcctcac ctgttgcaac ttttgtgaca ttgtcatgcg
     1861 ccacatccag cgtcaaacct ccattgttca tgaggatata gcgagaaatg ttccaaatct
     1921 tgttaataaa gttccatgaa gcatccattt tctcataaga gaaacgcacg tcttgtcctg
     1981 gcgcagaacc gtttgaaagg aaccatcgaa gggcatcggc accgtatttc tcgataacat
     2041 ccattgggtc aatcccgtta ccgagagact tagacatctt gcgtccttgc tcgtcacgaa
     2101 tgagaccgtg gataaggacg ttttggaatg gttgacggcc tgtgaattcc aatgactgga
     2161 agatcatacg agacacccag aagaagatga tgtcgtaacc tgttaccaag gttgaagttg
     2221 ggaaataacg tttaaagtct tctgagtcga cttcaggcca gcccatggtt gaaaatggcc
     2281 agagggcaga actgaaccaa gtatccaaga cgtcttcgtc ctgagtccat ccgtcacctt
     2341 ctggagcttc ttcgccgaca tacatttcac catcagcatt gtaccaagca gggatttggt
     2401 gaccccacca gagctgacga gagataaccc agtcgtggac attttccatc cattgaagga
     2461 aggtatcgtt gaaacgaggt gggtagaatt cgaccttgtc ctctgtgtct tggttggcaa
     2521 tggcgttctt agccaattgg tccatcttga cgaaccattg agtagacaag cgtggctcaa
     2581 ctacgacacc tgtacgttct gagtgaccaa cactgtggac acgtttttcg attttgacaa
     2641 gggcaccgat ttcttccaac ttagcaacga ctgccttacg agcttcaaaa cgatccatgc
     2701 ctgaaaattc aaaggcaagc tcgttcatag ttccgtcgtc gttcatgatg ttgacttgtg
     2761 gcaagttatg acgttggcca accaagaagt catttggatc gtgggcaggt gtgattttca
     2821 cgacaccagt accaaactca ggatctgcgt gctcatctcc aactattggg atgagtttat
     2881 tagcgattgg aaggatgacg tttttaccaa tcaagtcctt gtagcgcggg tcttctggat
     2941 taaccgcaat cgcaacgtcc ccaaacatag tctcaggacg agttgtagca acttcaaggg
     3001 cgcgtgaacc atcttccagc atgtaattca tgtggtagaa ggcaccttcc acatccttgt
     3061 gaatcacctc aatatcagaa agggctgtgc gagctgctgg gtcccagttg atgataaact
     3121 caccacggta gatccagcct ttcttgtaaa ggtccacaaa gaccttacga acagcttttg
     3181 acaaaccttc gtcaagagtg aaacgctcac gagaatagtc tacagagagc cccatcttgc
     3241 cccattgttc cttgatggta gtggcatatt cgtctttcca ttcccagact ttcgtcaaga
     3301 aagactcacg accaaggtca tagcgggaaa tgccctcacc acgcaagcgc tcctcaacct
     3361 tagcctgagt ggcaatccct gcgtggtcca tcccaggaag ccaaagggta tcaaaacctt
     3421 gcatgcgttt ttgacggatg ataatatctt gcaaagttgt atcccaagcg tgaccaaggt
     3481 gaagtttacc tgtaacgttt ggtggtggaa taacgattga ataaggctta gccttttgat
     3541 cgcctgaagg cttgaaaaca tcagcatcaa gccatttttg gtaacgacca gcctcaacct
     3601 cggctggatt gtatttagat gaaagttctt tagacatgtg tgttctcctt aattactttt
     3661 attgacaatt ttaaccaaac caatttttga aagttcaata taaatctctt caatttcagc
     3721 aaatgctgca agtggtgaca tagtataatt tccaggatta tatttaagat catacttgct
     3781 tatctttgaa atataatacc tagagtgttt caattttaat gattccaact ttgatttaat
     3841 atctactaat gtattatggt ttaactttaa aaacaactta ttataattac catagagctc
     3901 tgtaagagca ttaaagtatt ctttcactag agctatagcg tcaatcttag atgtttcttg
     3961 gtttagtttt atcaactccc ctttcaattt tttccattta aagttggaat ttaaaagata
     4021 atctaaatca atatagaaat ctattataac agtctcatca tctgggctaa cagcttttac
     4081 ctcatttatt ggtaagtcag tatgttgcga ataatttctc aaagaatggc aaaatcgata
     4141 agtaaaattg atatcatact gatagcttgc aaaaccatgt atacaatcaa actcctcact
     4201 atctttggaa tatttttgtt taatttggtt ttcgttaaaa tcgacaaaca attttccact
     4261 ggataataaa tgaatcatga aacgatttac atctgcctct tcaatttcta attcctttga
     4321 ctcaagttta tttttaatac ttaaaaaatc cgagacatct gaaataaaca attcgaacat
     4381 attcttgatt ttttgaaaat tcttttgaat ctcaaaaatt tggtccgaga ctgacattat
     4441 ttccttggtt ggttcaatat cagagatgac aatacgtttt tcattgttgt taatttctaa
     4501 ataagctaat cgctcgataa tatcactatc atttaattca gcatactcaa catcaatttg
     4561 gcgtaactgc ttctcagata gagagcttac ttcctctttt acatcgctca tcttattcct
     4621 cccactcgct cttcagcaag ccatatatca gactgtcaca gcggtttcct tgaacatcct
     4681 ttcggtctct tatgcgagct tcgagggtaa agccaagctt ttccgcgact cgtttacttt
     4741 gaaggttata tccaaagcaa gttagttcaa tcttgtgaag acccaaatct ttaaaggcta
     4801 agtcaatcaa ggcacgcgca gcttctggca cataacctcg cccccaatag tctgggtgta
     4861 aggtatagcc gatttccagc acatcatctt catggcgatg gttgaaatcg acagagccaa
     4921 cgatcttatc cgttactttg acgacaatcc cgtagcctgc tgggagattt tccttttgat
     4981 tacgctccgg aagaatgtgc tccagataat aaatctcatc ttccaaggtc ttgactggag
     5041 gaaaacctgc tggataggcg acctctggca aactagcata gtcaaagata tcctcagcat
     5101 ccgccacagt acggactcgt aaaacgagac gttctgtttc gattttatct ggcagctcag
     5161 ttcttgccat ccttcttcct cgcttttttg atgaaaccgc ccttcatatc tacacgctta
     5221 tccagatagc gataaacgcg ctgatatcca tctcccatga aataggttgg ggcaaacagt
     5281 tgatttttaa aatgtccctt ttcatccagg agttctgggg caacaagtcg ctcaagaatc
     5341 ttggcaaaga tgtggcaaat accgtcttcc tcaacaatcc tatctacccg acaatctaaa
     5401 acaagtggac aggcgtctaa aataggaatc tgagttcgtt cagaaatttc ataatgcact
     5461 cccaaacgtt ccaatttctc ctgatgactg ataaaaccag cctgctccat cgcaagcata
     5521 gaagtttcat cagaaatatt cacagtaaat ttttgatact gtttgatctg ctctgcggca
     5581 ttctctctcg caacgactcc aatcacaacc caatctccta gactataaga ggaactacag
     5641 gtcgtgatgt tatagccaaa attctaatct tgatatccta aaataaaaac aggaaaacca
     5701 taatatagtt tattagtttt aaatgattgt tttataacaa cctcctttga ctaagacaca
     5761 aaagaaaagc cctgccatct acatgacagg gacgaatgtg tttatccgcg gtaccaccca
     5821 atttcgggcc aagcccgcat ctttagtctt taaaataaaa agacagaaat atttcatttt
     5881 ttcagtcatt agcaaccagt tttgacacat ttgtggactt ctcagcgccg ccactttctg
     5941 taaaatgtgg gattcaaaac acctctaatg gctctattgt agcaagtttt tctcggaaat
     6001 gcaaggctca agaaaaatta cttgaacttg atgccatttt ctttcaattt cttgatggta
     6061 gctgggtcga ttcctttcaa gtcaaggagt tctttttcag tccagttttt gaaatctgaa
     6121 gcagacttga ttccttcatc atagaaagtc ttggcacgat caagtggaag tccacccaag
     6181 tttgctgcaa aatcttctac agaattagct actttttgag cttgctcttt ggtagcttct
     6241 actgcttgtt caactttttt agaaacagcc ttaccagctg cgcttgctga ctgttctgca
     6301 cgcttcacga ctttttttgt ctcatctaca accttagtca cagtacttga aaaggcacct
     6361 gagcgacgga ggccatttcg taattgtttt ttacgattga gtttctttga catgataaaa
     6421 tcctttcaat aaaaaatccc tgctctgaca aggatttaac ataaacattc tatcaagatt
     6481 ttagtgaaaa atcaagaatc tttctcgttt aataatttcg ctcaccaaac aagccttctg
     6541 gcaaatcatg gaatcccttg cctgctttga agttttcaaa cttaccaagc aagaactgat
     6601 aagcatccaa gcgactctcg tagcgaatca tggcatcttt ggcacgctcg tcctggtctt
     6661 cttcgtaaac tttttgactt tccttgtgcg ccatatcgtt aatcatgatt tgggtattga
     6721 cccaagcttc aaattccttc ataaattctt gttcgtaact cattttttct ccttattcta
     6781 atccacggaa atagtccgta tcaatctcac ggtagggctg gatatcctga acatactcca
     6841 acactccttg gaattctccg tcttcatcgt gtactgcagc ataggtgatg tggacaaact
     6901 tgcctcgcga ctcagacttg aaccacattt catacttgtc cttggtcccc tcacgaagtc
     6961 ccttcatgat agccttgacc ttgtccaaat acttaggcgg atgacagagt tcgacattgc
     7021 gcccgacttg ggacggcgtt cgtttgaaaa tcatctcatc agctggcgta ttgtcattgt
     7081 aatactggaa aatatcttct ttattgacaa aggtaatctc catagggaga tgattgagga
     7141 tgagattggc ctgctcgact gaaagatagc cattaccaaa agcctgttga ctatggcggt
     7201 ccagcacagc ttccttttcc ttaggggtaa aggtaatggt aaaatggcct tctggcgtat
     7261 ctatgacttg ttgaacttga ccttctgccg tatctagctg tacaggctcc tctgcaatct
     7321 tttcctcaat aaagctctgt cgttctggca cccatttctc tgacggacgg atgatggcat
     7381 agccataggc atcgctctcc tccgcaatct gaatccagtc atcctgagta aaagactcaa
     7441 ggagaatcat gaggaggatg gactcttcct tgaaaatcat actttcaaac tctgtcgcaa
     7501 aagcttcaaa agcttccttt acactgctaa ttgacacttc tggtagtgac ttggctgtcg
     7561 ttagagctgt ttgaaagagt tccctaatct gatcatccac tccccacata actttgggag
     7621 gtgaatcgtg tccatagcgc tccatgatag gaaagaagag ttcttcttta cgttggtaat
     7681 ggatgtcaaa ttgccccaca agtcccatct gacgcaccaa gcccttgcgc atctccgcca
     7741 gcatttcctc gtcttccatc aactcatagg tatctaacaa tctacgaatg cgaatcaaag
     7801 ctgcacggag ggccaaattt tcttccttaa agacacgaac tgggtgccca gggtgttcgg
     7861 tatctaaaac ttcgacacct ttgatagcat ttttaaaaag attggcatgg acatcacaga
     7921 gttccataac atcttcaaaa gtgacgcccg aatccgagtt catcagctcg tgctccataa
     7981 gggaaatctc gatggctgac acgcccgtaa aggtcgcatc aaagcgatct tgaaccgact
     8041 caggagaggc gccattgtgc aattctaaca aaatatcccg taggatatga atccgttcat
     8101 ctgtcattag tctaatccaa tcacttcgta gccattcgct tccagtgtgc gtacaatctt
     8161 gtccatagga gttcctgcta gcttagaacc ctgtttaagt gatactttac gaccaactgt
     8221 attgcgcatt aagggattgg caaggggttt aaaacccaac tccactagaa tttccaagac
     8281 ttctggatgc ttgtccacca cttctgcaac aggaattgac acatcgatga tattgtccat
     8341 gacgacctcc attgtatctt ctaatactca atgaaaatca aagagcaaac taggaagcta
     8401 gccgcaggtt gctcaaaaca gtgttttgag gttgtagata gaactgacga agtcagctca
     8461 aaacaccgtt ttgaggttgt ggatagaact gacgaagtca gtaacatata tactgcaagg
     8521 tgaagctgac gtggtttgaa gagattttcg aagagtataa aatgatttta ctgcttatat
     8581 tataccatat ggagagagat taaaaaacta gcagtggagt tcctgctagt tttctgcgac
     8641 ttggattacc atctagataa gtttaaagaa ccaatccaat atcttgtaaa acagcaattg
     8701 aactgcaaaa gaaatgatca tccaaaagaa tttcacaatc ccaataatcg gtttgataaa
     8761 aataatggca agaagtcccc agaaaaattt cattctctct cctctggctt aatgagccac
     8821 cgagccgtat ccattaactt gtcggcaata aaaagtttcc ccagaccgac aacggcatta
     8881 tcatctttct ttatcgtttt cattactttt acaccttgca cggtcaaaaa gtaattacca
     8941 taaattttag ctagagtttt tatgagtccc atattactct ccttcgatga tttcagcctc
     9001 ttttcggatt gtttcaacat cttcttgata ttgaacttca ctatagttaa ctagcttgga
     9061 caattctttc tgcaagcttt cacccatcgg tttcatagtt gcaaaggtta aaccacctga
     9121 aatgatacca cccaagatag gaataaattt ccccattcct ttggccagcc ctcccttggt
     9181 aagattcaca ccaaatattc ttaagacttt tttcaaaata ggataccaaa gcgtctttgt
     9241 taaagcttta ttaggtactg ttttcattac ctgtttggca attgttatac caccagcacg
     9301 tagcaaagca gcagttccat tcacccccaa catgacgcct agataaagca aaagggtatt
     9361 ttgagcatct tcactcaact catcgcgtga agcccaaaga tcctcataac cataaatata
     9421 acctaattct tgggccaatt tcagagagaa accataaaat tgagccacat cagctggaat
     9481 ggtaattgcc atagcaagcc ctccaggtaa tcctgccaaa acagaagtcc cactcgctaa
     9541 taaaacatta tccctaatac aggcattagc cactcgatct aagatttctt gagataagag
     9601 agacgttgga ccttgttcca ataaggtagg aatgtcctgt ggacccaatt ctttggaaaa
     9661 cttatccact aaaaatttcg aacgatcaac cttaacaact ggtagtttta ccacttgttg
     9721 taatacttgc atagctaagt cttgttcagc catatacaaa ctccttattt cttttttaca
     9781 ccttatcata ttatatttcc tacaaaaaaa gcattttcta attagataac attaaaaaat
     9841 acagaacccc tttt
//
LOCUS       DAVKXA010000064         9853 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKXA010000064 DAVKXA010000000
VERSION     DAVKXA010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.064"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            126..2054
                     /gene="glgB"
                     /locus_tag="VW883_001891"
     CDS             126..2054
                     /gene="glgB"
                     /locus_tag="VW883_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0274972.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVIMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2044..2577
                     /locus_tag="VW883_001892"
     CDS             2044..2577
                     /locus_tag="VW883_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0274973.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEF"
     gene            2614..3186
                     /locus_tag="VW883_001893"
     CDS             2614..3186
                     /locus_tag="VW883_001893"
                     /inference="COORDINATES: protein motif:HMM:NF012695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0274974.1"
                     /translation="MGIYIFDWQRLRNMLVAAEKSKVGMSDFGKNVIPNYLESGESVY
                     AYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYSRNLISPPNFLGANAHV
                     EDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAIIGQGAKIKRAIIGEGA
                     IISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3176..4315
                     /gene="glgD"
                     /locus_tag="VW883_001894"
     CDS             3176..4315
                     /gene="glgD"
                     /locus_tag="VW883_001894"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0274975.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4312..5745
                     /gene="glgA"
                     /locus_tag="VW883_001895"
     CDS             4312..5745
                     /gene="glgA"
                     /locus_tag="VW883_001895"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0274976.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5804..6175
                     /locus_tag="VW883_001896"
     CDS             5804..6175
                     /locus_tag="VW883_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0274977.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6120..6344
                     /locus_tag="VW883_001897"
     CDS             6120..6344
                     /locus_tag="VW883_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0274978.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            6458..7573
                     /locus_tag="VW883_001898"
     CDS             6458..7573
                     /locus_tag="VW883_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0274979.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLEHTAANIRRLLSLSKI"
     gene            complement(7570..8016)
                     /locus_tag="VW883_001899"
     CDS             complement(7570..8016)
                     /locus_tag="VW883_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEV0274980.1"
                     /translation="MTDLSKQLLEQAHGGAKLNPDEQRRYLGTFEERVLGYADIDTAN
                     SPQLEKGFLSILEKLQEKADPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHTS
                     SPFGLIIHSNAPVQVEEKNLRLAFPKLWEGKKEEPAKTSIWKKWFS"
     gene            8180..9484
                     /gene="eno"
                     /locus_tag="VW883_001900"
     CDS             8180..9484
                     /gene="eno"
                     /locus_tag="VW883_001900"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0274981.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAIATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9622..9759)
                     /locus_tag="VW883_001901"
     CDS             complement(9622..9759)
                     /locus_tag="VW883_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEV0274982.1"
                     /translation="MPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKI
                     F"
BASE COUNT         2943 a         1753 c         2188 g         2969 t
ORIGIN      
        1 aacgagtaag tgaacttgtt gtagattttc aaaataatta aagaagtata gtaatttact
       61 tgaatcttct ctaaaaaggt agtataataa aaacatagaa aacgcttaca ggagaagggg
      121 agtatatgga taatagagaa gcattaaaaa cctttatgac gggtgaaaat ttttatctcc
      181 aacattatct aggagcacat agggaagaac taaatggaga gcatggctat accttccgtg
      241 tttgggcacc taatgctcag gctgttcact tggttggtga ttttaccaac tggattgaaa
      301 atcagattcc aatggtaaga aatgattttg gggtctggga agtctttacc aatatggctc
      361 aagaagggca tatttacaaa tatcatgtca cacgtcaaaa tggtcatcaa ctgatgaaga
      421 ttgacccttt tgctgtcagg tatgaggctc gtccaggaac aggggcaatc ttaacagagc
      481 ttcctgagaa gaaatggaag gatggacttt ggctggcacg aagaaaacgt tggggctttg
      541 aagagcgtcc tgtcaatatt tatgaagttc acgctggatc atggaaaaga aattctgatg
      601 gcagtcctta tagttttgcc cagctcaagg atgaactcat tccttatctc gttgaaatga
      661 actatactca tattgagttt atgcccttga tgtcccatcc tttgggcttg agttgggggt
      721 atcagcttat gggttacttc gctttagagc atgcttatgg ccgaccagag gagtttcaag
      781 attttgtcga ggagtgtcat acccataata ttggggttat tgtggactgg gtaccaggtc
      841 actttaccat caacgatgat gccttagcct attatgatgg gacaccgact tttgaatacc
      901 aagaccataa taaggctcat aaccatggtt ggggtgccct taattttgac cttggaaaaa
      961 atgaagtcca gtccttctta atttcttgca ttaagcattg gattgatgtc tatcatttgg
     1021 atggtattcg tgtggatgct gttagcaaca tgctctattt ggactatgat gatgctccat
     1081 ggacacctaa taaagatggc ggaaatctca actatgaagg ttattatttc cttcagcgct
     1141 tgaatgaggt tattaagtta gaatatccag atgtgataat gattgcagaa gaaagttcgt
     1201 ctgcgaccaa gattacggga atgaaagaga ttggtggtct aggatttgac tacaaatgga
     1261 acatgggctg gatgaatgat atcctccgtt tctacgaaga agatccgatc tatcgtaaat
     1321 atgactttaa cctggtgact ttcagcttta tgtatgtttt caaggagaat tatctcttgc
     1381 cattctcgca cgatgaagtg gttcatggca agaagagtat gatgcataag atgtggggag
     1441 atcgttacaa tcaattcgca ggcttgcgca atctctatac gtaccaaatt tgtcaccctg
     1501 gtaagaaatt gctcttcatg ggtagcgaat acggtcaatt cctagaatgg aaatctgaag
     1561 aacagttgga atggtctaac ctagaagacc caatgaatgc taagatgaag tatttcactt
     1621 ctcagctaaa ccagttttac aaagatcatc gctgtctgtg ggaaatcgat accagctatg
     1681 atggtattga agtcattgat gcggataatc gagaccagag tgttctttcc tttattcgta
     1741 agggtaaaaa gggagaaatg ttagtctgta tctttaacat ggtacctgtt gagcggaaag
     1801 attttacaat cggactaccc gttgcaggaa tttacgaaga agtatggaat actgagttgg
     1861 aagagtgggg aggcgtttgg aaagaacata atcaaactgt tcaaacgcaa gaaggactat
     1921 ggaaagatta tgagcagacc ttaaccttta ccctaccggc tatgggagca agtgtatgga
     1981 aaatcaaacg tcgcttgaaa tctactaaaa ccgtcacaaa taaaaaccaa aaaggagtag
     2041 aaaatgaaaa atgaaatgtt agctttgatt cttgctggtg ggcaaggaac tcgtctcggt
     2101 aaactcactc aaagcatcgc aaaaccagct gtgcaatttg gtgggcgcta ccgtatcatt
     2161 gactttgccc tatcaaactg tgccaactca gggattcata atgttggggt cgttacacag
     2221 tatcaaccac ttgctctcaa caaccatatt gggaatggtt caagctgggg actagacggt
     2281 attaattcag gtgtctctat tcttcaacct tattctgcaa gtgaaggaaa tcgttggttt
     2341 gaggggacta gtcacgctat ttaccaaaat atcgactata tcgacagtgt caatcctgag
     2401 tatgtcttga ttttgtctgg ggatcacatc tacaaaatgg actatgatga tatgctccag
     2461 tctcataagg ataataatgc cagcttgaca gtagcagttt tagacgtccc tcttaaagaa
     2521 gcaagccgtt ttggtatcat gaacacagat gctaacaatc gtattgttga attttaagaa
     2581 aaaccagctc aacctaaatc tacaaaagct tctatgggaa tctacatttt tgattggcaa
     2641 cgccttcgta atatgttagt cgctgctgaa aagagcaagg ttggcatgtc agactttggt
     2701 aaaaatgtca ttccaaatta ccttgagtca ggtgaaagtg tttatgctta cgaatttagt
     2761 ggttattgga aagatgttgg tactattgag tcactttggg aagcgaacat ggagtatatt
     2821 tctccagaaa atgccttgga tagtcgtaac cgtcaatgga agatttactc aagaaacttg
     2881 atttcaccac caaacttcct cggggcaaat gctcatgtgg aagactcatt agttgtagac
     2941 ggatgtttcg ttgatggaac tgttaaacat tctatccttt caacaggcgc gcaagttcgc
     3001 gaaggagcgg aagtccttga ttcagttatc atgagtggag ctatcattgg tcaaggagct
     3061 aagattaaac gtgccattat tggtgaaggt gcgattattt ctgacggtgt cgaaattgat
     3121 ggaacagatg aagtacaagt tgtaggatat aatgaagtag tgggggtagc aacagatgaa
     3181 gattgataaa tattctgcca ttttaggaaa tacagttggt tttcacaata tgtcgacatt
     3241 gacggaccac cgtccagtag caagtttgcc atttggtggg aaatatcgtt tgattgactt
     3301 cccactttca agccttgcta atgcaggtgt tcgtagtgtc tttggtattt tccagcagga
     3361 taatatcagc tcagtatttg accatattcg ttcaggacgc gagtggggct tatcaaccct
     3421 tcttagccat tactatctag gaatttacaa tacccgtgta gaaagtagta cagttggaaa
     3481 agaatactac caacagcttc ttacttattt gaaacgttct ggctcaaacc aaacggttgc
     3541 cctcaactgc gatgttctta ttaacattga tttgaaccaa gttttccacc tacatagtac
     3601 aacaaaagag cctatcactg tagtttataa aaaactagct aagaaagata tttcagaagt
     3661 aaatgcaatc ttggatgtag atgaaacaga ccatgttctt tctcataaac tctttgatag
     3721 caagtcaaca gctgaaacgt tcaatatgtc tacagatatc tttgtcgttg atacaccttg
     3781 gttgattgaa cacttggaag aagaagctaa aaaagaacat ccagagaaat tgcgctatgt
     3841 tttacgggat ttggctgtaa aagagggagc tttcgcctac gagtacacgg gctatctagc
     3901 caatattcac tctgttaaat cttattatca agcgaatatc gatatgcttg aatcacaaaa
     3961 attctattct cttttctcac caaaccaaaa gatttataca aaggtcaaaa acgaagagcc
     4021 aacttactat gctaatacat ctaaggtaag aacttctcag tttgcctctg gtagtattat
     4081 tgaaggtcaa gtagctaatt ctgttctatc acgtaatatc catgtccata aggatagctt
     4141 ggttaaagat agcctgctct tccctcgtgt tgttattgga gaaggggctc aggtcgaata
     4201 tgctatcttg gacaaagggg ttgaagttga gcctggtgtt gtgattcgag gaactgcaga
     4261 acatccagtt gtggttaaga aaggtgctaa agtaacagag gatattcatt catgaaaatt
     4321 ttatttgtag cagcagaggg tgcacccttt tcaaaaacag gtggtttggg agacgtcatt
     4381 ggcgctcttc caaaatcact ggtaaaagct gggcacgaag ttgcagtgat tttaccctac
     4441 tatgatatgg tagaggctaa atttggaaat cagattgaag atgtgcttca ttttgaggtg
     4501 agcgttggtt ggcgcagaca gtattgtgga attaagaaaa cagtattaaa tggtgtaacc
     4561 ttctacttta ttgacaatca atattatttc ttccgtggtc atgtttacgg tgattttgat
     4621 gacggagaac gctttgcctt tttccaactg gctgccattg aggctatgga aaggattgac
     4681 tttattcctg atcttctcca tgttcatgac taccatacag ctatgattcc tttcttgttg
     4741 aaggaaaaat accgttggat tcaagcctat gaggacattg aaacagtttt aaccattcat
     4801 aatttagaat tccaaggaca attttcagaa ggaatgttgg gtgatttgtt tggagttggc
     4861 tttgaacgtt acgctgatgg cacccttcga tggaacaact gtctgaactg gatgaaggca
     4921 ggtattctct atgcgaaccg tgtttcaacc gtttcaccta gctatgctca tgaaattatg
     4981 actagtcagt ttggatgtaa tttggatcag attcttaaaa tggagtctgg taaagtatct
     5041 ggtatcgtga atgggattga tgctgatctt tataatcctc agacggatgc tcttttagac
     5101 tatcatttca atcaggaaga tttgtctggg aaagccaaaa ataaggcaaa attgcaagaa
     5161 agagttggct tgcctgttag agcagacgtt ccactggtgg gaattgtttc tcgtttgaca
     5221 cgtcaaaaag gttttgatgt ggtggtcgaa agtcttcacc atatcttgca agaagatgtt
     5281 cagattgttc ttttgggaac tggcgatcca gcctttgaag gagctttctc atggtttgct
     5341 cagatttacc cagacaagct atcaacaaat atcacttttg atgtcaaact tgctcaggaa
     5401 atctacgctg cttgtgacct cttcctcatg ccaagtcgtt ttgaaccgtg tggcttgtct
     5461 caaatgatgg ctatgcgtta tggaaccttg ccattggtcc atgaagttgg aggcttgcga
     5521 gatacagttc gcgctttcaa tccaatcgaa ggaagcggta ctggctttag ctttgacaat
     5581 ctatctcctt attggttaaa ttggactttc caaacagcat tggacttgta tagaaaccat
     5641 ccagacattt ggagaaacct acaaaaacaa gctatggaga gtgacttctc atgggataca
     5701 gcctgcaagt cataccttga cttgtaccat agtttagtta attaatagat aaaatcgtat
     5761 gatgacttca tacgattttt aggctgttta gagaggagaa ctgatgtctc aagtaaaagg
     5821 cttgtgtgtt ttggatgtag atggaacctt aatcctagaa gaagtgattg atcttttagg
     5881 gagagaggca ggtcatgagg cggaaatttc gcagattaca agtcgagcaa tgcgaggaga
     5941 gttggtcttt gaaagcagtt taagaaaaag agtgtccttg ttggaaggtc ttcctatttt
     6001 ggtctttgat aacgtcttca actcaattca tctatcgcta aatgtcccag agttcatctc
     6061 tattctccaa aagaatggca tcctagttgg tctggtgtct ggtggattta caccaatagt
     6121 tggagagatt agcaaaatcc cttggtattg cctatttcac tgccaaccag cttgaagtca
     6181 aagaaggtct tttaacagga aaattagttg gacaaattat aagtccccag gtcaaaaaag
     6241 aaactctgga aaaatggaga aagaaactaa aactttctaa agaaagaacg gtggcaatcg
     6301 gtgatggggt caataatcta ttaatgttga agtcggcgga gtgaggaatc gccttttgtt
     6361 ccaaagaaat gctcaaaaaa gaaataccac atcatgttga caagagggat tttttagaag
     6421 ttcttccttt gattgactgt ttagaatgag ggaaaatatg aagattgtaa ttgcaccgga
     6481 ttcgtttaag gaaagcttga cagctcaaca ggtagctgaa gcaataaaaa gaggcttcca
     6541 acaatcgata gcagatgtag aatgtctcct ctgccctgtt ggtgatgggg gagaaggtac
     6601 tgtagatgct atccgacatt ctcttgacct aaaagaaaaa tggatccaag tgacagaccc
     6661 ttttggacaa aaagaagcca tgcgctattt tcaaaaaggg gaactggcac tatttgaagt
     6721 agctgacttg gttggtcttg gaaaaattcc gctagagaaa cgaaatccac ttcaaatcca
     6781 aacttgtggt attggagagt tgattctcca tctcatttct aaagggatta aagatattta
     6841 tatcggtgtt ggtggcacgg ccagtaatga tggaggactg gggattgctg ctggtttagg
     6901 ttatcaattt tatgataggg atggaaatgt cttgcctgct tccggtcaat ccttattaaa
     6961 cttagcttct gtttcaacag aaaattgcta taaaattcct gaaggtgttc aaattcatat
     7021 tttagcagat gtcgtgagtc ccttatgtgg tcatcaaggt gcgacttaca cttttggcaa
     7081 tcaaaaaggt ctacatccga ctatgtttgc agtcgtagat caggcgatcc aagattttta
     7141 tgaaaaattc tcacctgcaa cattagaaat taaaggagca ggagcaggtg gaggccttgc
     7201 tggtggtttg tgtgcctttg ctcaggcaag tatcgtgtct ggaattgata cctgcttgga
     7261 cttaatcaac tttgataaga aagtttcaga tgctgacttg gttgttgttg gagaaggaag
     7321 acttgatagt caaagctttg ctgggaaagc gcctataggt gttgcaaaaa gaacccctgt
     7381 tggagttcct gttattgcta tttgcggtag tcttgctgaa gatttacctc ccctaccatt
     7441 tgaaaatatc caagctgtct tttctatttt ggagaaaagt gaacctttag aagatagttt
     7501 gaaaaatgcc agtctctatt tggagcacac ggctgccaat attaggcgtt tattaagtct
     7561 gagtaagatt tagctaaacc atttcttcca gatggatgtt ttggcaggtt cttccttttt
     7621 accttcccaa agttttggaa aagcaagtcg aaggttcttt tcttctactt gtactggtgc
     7681 attgctatgg ataatcagac cgaaaggaga agaagtatgt tcctcagata ctatggtagc
     7741 ttgactatcg gtttctttgg cttccttcaa gtagaaaact tgcttgtcaa attcgatagt
     7801 tggtgaaatc ttcacaaata gtggatctgc tttttcctga agtttttcta aaatagataa
     7861 aaagcctttt tctaactgag gactatttgc tgtgtcaata tctgcatatc caagaactct
     7921 ttcctcaaaa gtaccaagat agcgtctttg ctcatccgga tttaattttg ctccaccatg
     7981 agcttgttca agtaattgtt ttgataaatc tgtcatgaaa acagtatatc ataaaagtta
     8041 gaataaaaca gacaaaagaa agcgattact ttataaagtt aaggaaaagt tgcacaaaga
     8101 taacgttttt tcttgaaaaa ggaggggttt taaggtatta tagaggtgta aaaaatttaa
     8161 ctcataagga gagtaaaaaa tgtcaattat tactgatgtt tacgctcgcg aagtcctaga
     8221 ctcacgcggt aacccaacac ttgaagtaga agtttacact gaatcaggtg ctttcggacg
     8281 tggtatggtt ccatcaggag cttctactgg tgaacacgaa gcagttgaac ttcgcgacgg
     8341 tgacaaatct cgttacggtg gtcttggtac acaaaaagct gttgacaacg taaacaacat
     8401 cattgctgaa gctatcattg gctacgatgt acgtgatcaa caagctatcg accgtgctat
     8461 gatcgctctt gacggtactc ctaacaaagg taaattgggt gcaaacgcaa tccttggtgt
     8521 gtctatcgct gtagctcgtg ctgctgctga ctaccttgaa atcccacttt acagctacct
     8581 tggtggattc aacactaaag ttcttccaac tccaatgatg aacatcatca acggtggttc
     8641 tcactctgac gctccaatcg ctttccaaga gttcatgatc ttgccagttg gtgcgccaac
     8701 atttaaagaa gcccttcgtt acggtgctga aatcttccac gctcttaaga aaatccttaa
     8761 atcacgtggt ttggaaactg ccgtaggtga cgaaggtggg ttcgctcctc gtttcgaagg
     8821 aactgaagat ggtgttgaaa ctatccttgc tgcgattgaa gctgctggat atgtaccagg
     8881 taaagacgta tttatcggat ttgactgtgc ttcatcagaa ttctacgata aagaacgtaa
     8941 agtttacgac tacactaaat ttgaaggtga aggtgctgct gttcgtacat ctgcagaaca
     9001 aatcgactac cttgaagaat tggttaacaa atacccaatc atcactattg aagatggtat
     9061 ggatgaaaac gactgggatg gttggaaagc tcttactgaa cgtcttggta agaaagtaca
     9121 acttgttggt gacgacttct tcgtaacaaa cactgactac cttgcacgtg gtatccaaga
     9181 aggtgctgct aactcaatcc ttatcaaagt taaccaaatc ggtactctta ctgaaacttt
     9241 tgaagctatc gaaatggcta aagaagctgg ttacactgct gttgtatcac accgttcagg
     9301 tgaaactgaa gattcaacaa tcgctgatat tgcaattgca actaacgcag gacaaatcaa
     9361 gactggttca ctttcacgta cagaccgcat cgctaaatac aaccaattgc ttcgtatcga
     9421 agaccaactt ggtgaagtag ctgaatatcg tggattgaaa tcattctaca accttaaaaa
     9481 ataaaatagt tcagtgaact attttatccc gaaccatgaa attcaaaagt tcggccgttg
     9541 atttaacaac gtttctagcc cctcggattt tatccgaagg gctatttttg tatttagagg
     9601 acaaaaaagg gacaaaactt tttaaaaaat ctttttcata actttatcca gtacattgat
     9661 tgcttcatct ttcatgttct ttgtgacgtg ggtgtagatg gaagtagtga cttcagagtc
     9721 ggaatgacca accctgtccg tgattgtttt taaaggaatt ttattggctc tttgtcaact
     9781 gtagtgggtt gaagaaaagc taagcttgag aaaggacaaa ttttgtcctt tcttttttga
     9841 tattcagggc gat
//
LOCUS       DAVKXA010000065         9585 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKXA010000065 DAVKXA010000000
VERSION     DAVKXA010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9585
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.065"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            89..6520
                     /locus_tag="VW883_001902"
     CDS             89..6520
                     /locus_tag="VW883_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0274983.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEATIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEARNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADHADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTEVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVEDFVTGGKRTVELDYKYDDKGNITAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDDDRIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSNLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVLKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            7147..7623
                     /locus_tag="VW883_001903"
     CDS             7147..7623
                     /locus_tag="VW883_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0274984.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7661..7966
                     /locus_tag="VW883_001904"
     CDS             7661..7966
                     /locus_tag="VW883_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0274985.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8014..9489
                     /locus_tag="VW883_001905"
     CDS             8014..9489
                     /locus_tag="VW883_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0274986.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT         3544 a         1442 c         1862 g         2737 t
ORIGIN      
        1 aatacttagt aaaacttttt ataacaaagg ctagcaaagt taaagtttat tatctattgg
       61 aagttaaata aatatgtaag gaattaaaat gaaaaaaagt acagtattgt cattaaccac
      121 agctgcagtt attttagcag cctatgcccc taatgaggta gtcttagcag acacatctag
      181 ctctgaagat gctttaaaca tctctgataa agaaaaagta gtattagata aggaaacaga
      241 aaataaagag aaacatgaag atattcataa tgctatagaa acttcacagg attttaaaga
      301 gaagaaaaca gcagtcattg agggaaaaga agttgttagt aaaaatcctg tgacagacaa
      361 taacactagc aatgaagaag caacaatcaa agaagattcc aatcaatccc aaggagatca
      421 tacggactca tttgtgaata aaaacacaga aaatcccaaa aaagaagata aacttgtcta
      481 tattgctgaa tttaaagata aagaatctgg agaaaaagca atcaagcaac tatccaatct
      541 taagaataca aaagttttat atacttatga tagaattttt aacggtagtg ccatagaaac
      601 aactccagat aacttggaca aaattaaaca aatagaaggt attacatcgg ttgaaagggc
      661 acaaaaagtt caacccatga tgaatcatgc cagaaaggaa attggagttg aggaagctat
      721 tgattaccta aagtctatca atgctccgtt tgggaaaaat tttgatggta gaggtatggt
      781 catttcaaat atcgatactg gaacagatta tagacataag gctatgagaa tcgatgatga
      841 tgccaaagcc tcaatgagat ttaaaaaaga agacttaaaa ggaactgata aaaattattg
      901 gttgagtgat aaaatccctc atgcgttcaa ttattataat ggtggcaaaa tcactgtaga
      961 aaaatatgat gatggaaggg attattttga cccacatggg atgcatattg cagggattct
     1021 tgctggaaat gatactgaac aagatatcaa aaactttaac ggcatagatg gaattgcacc
     1081 taatgcacaa attttctctt acaaaatgta ttctgacgca ggatctgggt ttgcgggtga
     1141 tgaaacaatg tttcatgcta ttgaagattc tatcaaacac aacgttgatg ttgtttcggt
     1201 atcatctggt tttacaggaa caggtcttgt aggtgagaaa tattggcaag ctattagggc
     1261 attaagaaaa gcaggcattc caatggttgt cgctacgggt aactatgcga cttctgcttc
     1321 aagttcttca tgggatttag tagccaataa tcatctgaaa atgaccgaca ctggaaatgt
     1381 aacacgaact gcagcacatg aggatgcgat agcggtcgct tctgctaaaa atcaaacagt
     1441 tgagtttgat aaagttaaca taggtggaga aagttttaaa tacagaaata taggggcctt
     1501 tttcgataag aataaaatca caacaaatga agatggaaca aaagctccta gtaaattaaa
     1561 atttgtatat ataggcaagg ggcaagacca agatttgata ggtttggatc ttaggggcaa
     1621 aattgcagta atggatagaa tttatacaaa ggatttaaaa aatgctttta aaaaagctat
     1681 ggataagggt gcacgcgcca ttatggttgt aaatactgta aattactaca atagagataa
     1741 ttggacagag cttccagcta tgggatatga agcggatgaa ggtactaaaa gtcaagtgtt
     1801 ttcaatttca ggagatgatg gtgtaaagct atggaacatg attaatccta ataaaaaaac
     1861 tgaagtcaaa agaaataata aagaagattt taaagataaa ttggagcaat actatccaat
     1921 tgatatggaa agttttaatt ccaacaaacc gaatgtaggt gacgaaaaag agattgactt
     1981 taagtttgca cctgacacag acaaagaact ctataaagaa gatatcatcg ttccagcagg
     2041 atccacatct tgggggccaa gaatagattt acttttaaaa cccgatgttt cagcacctgg
     2101 taaaaatatt aaatctacgc ttaatgttat taatggcaaa tcaacttatg gctatatgtc
     2161 aggaactagt atggcgactc caatcgtggc agcttctact gttttgatta gaccgaaatt
     2221 aaaggaaatg cttgaaagac ctgtattgaa aaatcttaag ggagatgaca aaatagatct
     2281 tacaagtctt acaaaaattg ccctacaaaa tactgctcga cctatgatgg atgcaacttc
     2341 ttggaaagaa aaaagtcaat actttgcatc acctagacaa cagggagcag gcctaattaa
     2401 tgtggccaat gctttgagaa atgaagttgt agcaactttc aaaaacactg attctaaagg
     2461 tttggtaaac tcatatggtt ccatttctct taaagaaata aaaggtgata aaaaatactt
     2521 tacaatcaag cttcacaata catcaaacag acctttgact tttaaagttt cagcatcagc
     2581 gataactaca gattctctaa ctgacagatt aaaacttgat gaaacatata aagatgaaaa
     2641 atctccagat ggtaagcaaa ttgttccaga aattcaccca gaaaaagtca aaggagcaaa
     2701 tatcacattt gagcatgata ctttcactat aggcgcaaat tctagctttg atttgaatgc
     2761 ggttataaat gttggagagg ccagaaacaa aaataaattt gtagaatcat ttattcattt
     2821 tgagtcagtg gaagaaatgg aagctctaaa ctccaacggg aagaaaataa acttccaacc
     2881 ttctttgtcg atgcctctaa tgggatttgc tgggaattgg aaccacgaac caatccttga
     2941 taaatgggct tgggaagaag ggtcaagatc aaaaacactg ggaggttatg atgatgatgg
     3001 taaaccgaaa attccaggaa ccttaaataa gggaattggt ggagaacatg gtatagataa
     3061 atttaatcca gcaggagtta tacaaaatag aaaagataaa aatacaacat ccctggatca
     3121 aaatccagaa ttatttgctt tcaataacga agggatcaac gctccatcat caagtggttc
     3181 taagattgct aacatttatc ctttagattc aaatggaaat cctcaagatg ctcaacttga
     3241 aagaggatta acaccttctc cacttgtatt aagaagtgca gaagaaggat tgatttcaat
     3301 agtaaataca aataaagagg gagaaaatca aagagactta aaagtcattt cgagagaaca
     3361 ctttattaga ggaattttaa attctaaaag caatgatgca aagggaatca aatcatctaa
     3421 actaaaagtt tggggtgact tgaagtggga tggactcatc tataatccta gaggtagaga
     3481 agaaaatgca ccagaaagta aggataatca agatcctgct actaagataa gaggtcaatt
     3541 tgaaccgatt gcggaaggtc aatatttcta taaatttaaa tatagattaa ctaaagatta
     3601 cccatggcag gtttcctata ttcctgtaaa aattgataac accgccccta agattgtttc
     3661 ggttgatttt tcaaatcctg aaaaaattaa gttgattaca aaggatactt atcataaggt
     3721 aaaagatcag tataagaatg aaacgctatt tgcgagagat caaaaagaac atcctgaaaa
     3781 atttgacgag attgcgaacg aagtttggta tgctggcgcc gctcttgtta atgaagatgg
     3841 agaggttgaa aaaaatcttg aagtaactta cgcaggtgag ggtcaaggaa gaaatagaaa
     3901 acttgataaa gacggaaata ccatttatga aattaaaggt gcaggagatt taagaggaaa
     3961 aatcattgaa gtcattgcat tagatggttc tagcaatttc acaaagattc atagaattaa
     4021 atttgctgat catgctgatg aaaaggggat gatttcttat tacctagtag atcctgatca
     4081 agattcatca aaatatcaaa agcttggcga gattgcagaa tctaaattta aaaatttagg
     4141 aaatggaaaa gagggtagtc taaaaaaaga tacaactgag gtagaacatc atcatcaaga
     4201 aaatgaagag tctattaaag aaaaatctag ttttactatt gatagaaata tttcaacaat
     4261 tagagacttt gaaaataaag acttaaagaa actcattaaa aagaaattta gagaagttga
     4321 ggactttgta actggtggaa aaagaacagt agaacttgat tataaatatg acgataaagg
     4381 aaatataact gcctatgacg atggtagtgc cttacaatat gaaactgaaa aacttgacga
     4441 aataaaatca aaaatttatg gtgttctaag cccatctaaa gatggacact ttgaaattct
     4501 tggaaagata agcaatgttt ctaaaaatgc caaggtatat tatggaaata gctataaatc
     4561 gatagaaatc aaagcgacta agtatgactc acattcaaaa acgatgacat ttgatttata
     4621 cgctaatatt aatgatattg tggatggatt agcttttgct ggagatatga gattatttgt
     4681 taaagatgat gatcgaataa aagctgaaac taaaattaga atgcctgaaa aaaataagga
     4741 aactaaagca gaatatccct atgtatcaag ttatgggaat gtaatcgaat taggagaagg
     4801 agatctttca aagaacaaac cagacaattt aactaaaatg gaatctggta aaatctattc
     4861 tgattcagaa aaacaacaat atctgttaaa ggataacatc attctaagaa aaggctatgc
     4921 actaaaagtg actacctata atcctggaaa aacggatatg ttagaaggaa atggagtcta
     4981 tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct aatctaagag tcctttcaga
     5041 aacaacaatt tatgctgata gtagaaatgt tgaagatgga agaagtaccc aagctgtatt
     5101 aatgtcggct ttggacggct ttaacattat aaggtatcaa gtgtttacat ttaaaatgaa
     5161 cgataaaggg gaagctatcg ataaagacgg aaatcttgtg acagattctt ctaaacttgt
     5221 attatttggt aaggatgata aagaatacac tggagaggat aagtccaatg tagaagctat
     5281 aaaagaagat ggctccatgt tatttattga taccaaacca gtaaaccttt caatggataa
     5341 gaactacttt aatccatcta aatctaataa aatttatgta cgaaatccag aattttattt
     5401 aagaggtaag atttctgata agggtggttt taactgggaa ttgagagtta atgaatcggt
     5461 tgtagataat tatttaatct acggagattt acacattgat aacactagag attttaatat
     5521 taagttgaat gttaaagacg gtgacatcat ggactgggga atgaaagact ataaagcaaa
     5581 cggatttcca gataaggtaa cagatatgga tggaaatgtt tatcttcaaa ctggctatag
     5641 caatttgaat gctaaagcag ttggagtcca ctatcagttt ttatatgata atgttaaacc
     5701 cgaagtaaac attgatccta agggaaatac tagtatcgaa tatgctgatg gaaaatctgt
     5761 agtctttaac atcaatgata aaagaaataa tggattcgat ggtgagattc aagaacaaca
     5821 tatttatata aatggaaaag aatatacatc atttgatgat attaaacaaa taacagacaa
     5881 gacactaaac attaagattg ttgtaaaaga ttttgcaaga aatacaaccg taaaagaatt
     5941 cattttaaat aaagatacgg gagaggtaag tgaattaaaa cctcataggg tgactgtgac
     6001 cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg gaagaagatt ttattttacc
     6061 tgtttataag ggtgaattag aaaaaggata ccaatttgat ggttgggaaa tttctggttt
     6121 cgaaggtaaa aaagacgctg gctatgttat taatctatca aaagatacct ttataaaacc
     6181 tgtattcaag aaaatagagg agaaaaagga ggaagaaaat aaacctactt ttgatgtatt
     6241 gaaaaagaaa gataacccac aagtaaacca tagtcaatta aatgaaagtc acagaaaaga
     6301 ggatttacaa agagaagatc attcacaaaa atctgattca actaaggatg ttacagctac
     6361 agttcttgat aaaaacaata tcagtagtaa atcaactact aacaatccta ataagttgcc
     6421 aaaaactgga acagcaagcg gagcccagac actattagct gccggaataa tgtttatagt
     6481 aggaattttt cttggattga agaaaaaaaa tcaagattaa gataaaagct atagaaaaaa
     6541 atggtttatg tactgagatt agatagtgag gtgatgacat agttttgtga aaacagccat
     6601 ttataactca attatttagt ttacttcact attgatacta tttggagtta ttaatgaact
     6661 tagtttagat aactaatgaa ttgattgaaa gggttagtat tgacaatatt ggtcatattg
     6721 attagaaaat aaagtctatc aaaatttaaa ggctaataga ggtgatgaga caatttcaag
     6781 gaattaagta gcgtttggtt gcttaattcc tttttatttg gaaggaagtt tttcgtaacc
     6841 gcccaataac gaagtctatt gggcggttac gatatgatca ctgacttcgt cagtcttatc
     6901 tacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagctt actctttgat
     6961 tttcattgag tattagaaca gaaaaaatgc ttggagtatt tgtttgtgtg tttattttta
     7021 tataacaaac tataaacaaa acaaaaatat aaaaaaagag acaaaaaaga acagaaagca
     7081 attgacaacg gtttcatata gtgttatact tatggcataa agttaatgga aagaagggaa
     7141 aaacttatgg tattagatta tttctttgac aaaaaccttg tgttttgctt agaagcggat
     7201 aatcaagaac atctctttga tcaggttgca actttattgg aagaacgaga aattgtaact
     7261 ccaacttatc gtgaagcctt gatcacgcgt gaaaagtcat ttccaactgg tttagatatg
     7321 gaatttctag gaaaggactt gccaaatgta gcgattcctc atacagatat tgttcataat
     7381 ctagctgaga aagtggtggt tgttcgatta gaaaaaccag taacttttca caatatgata
     7441 gctcctgata aggaagtaga agtatcccta cttttcttta tcattaacaa ttcaagttca
     7501 agtcaaacaa atattctggc tcagttgatg gactttttca caggaaatgg acatcttgaa
     7561 gacctatcaa aaatttccga accagaaaaa ctttatgctt acattgctga agcaaccgct
     7621 taatcttgtc tattaaaaaa taaaatcgga ggaaatccaa atgattaaaa ttcttgctgc
     7681 ctgcggtgca ggtgttaact caagtcacca aattaaaagt gctctagaag aagaactttc
     7741 aaaccgtggt tatgatgttc actgtgatgc agtcatggtg aaagatgtaa acgaagacct
     7801 tatgaaaggt tacgatatct ttacaccaat cgctgcaaca gaccttggtt ttgaaccagg
     7861 tatcccagtt atcgaagctg ggccaatctt attccgtatc ccagcaatga gcgctccagt
     7921 atttgacaat attgaagcag ctattaaaga acatggatta agctaattct aatttgttaa
     7981 cattcatata acataaaaaa gggaggaact gttatggatg caatctttga cctaatcgga
     8041 aaggttttca atcccatctt agaaatgggt ggacctgtca tcatgttgat cattttgaca
     8101 gtattggctt tactttttgg agtgaaattc tccaaagcgc ttgaaggtgg tatcaaactt
     8161 gccatcgctc ttacaggtat cggtgctatc atcggtatgc taaatggtgc tttctcagca
     8221 tcacttgcaa aattcgttga aaacactggt atccaattga gtattacaga cgttggttgg
     8281 gcaccactcg caacaatcac ttggggttct gcttggacac tatacttctt gctcatcatg
     8341 ttgattgtca acgtagtgat gcttgctatg aagaaaaccg atacacttga tgtcgatatc
     8401 tttgatatct ggcacttgtc tatcacaggt ctcttgatta aatggtatgc tgataacaat
     8461 ggtgtgagtc aaggggtttc actctttatt gctacagcag ctatcgtcct tgtcggtgtg
     8521 ttgaaaatta tcaactctga cttgatgaaa cctacatttg atgaccttct taacgctcca
     8581 agttcatcac caatgacatc aactcacatg aactacatga tgaacccagt tatcatggtt
     8641 ttggataaga tttttgaaaa attcttccca ggccttgata aatatgactt tgatgctgct
     8701 aaattgaaca agaaaatcgg tttctgggga tctaaattct tcatcggttt catccttggt
     8761 atcgttatcg gtattatggg aactccacat ccaattgcag gtgttgcaga tgcagataaa
     8821 tggcgtcttg ttatcaaagg atggttgtct cttggtttga ctgccggtgt atctttggaa
     8881 ctcttctcac ttatcggttc atggttcatc gcagccgtag aaccactatc acaaggtatt
     8941 acaaacgttg ctactaaacg tcttcaagga cgtaaattca atatcggtct tgactggcca
     9001 ttcatcgctg gtcgtgctga aatctgggct tgtgccaacg tacttgcacc aatcatgttg
     9061 attgaagcag tgcttctttc aaaagttgga aatggtatct tgccacttgc aggtatcatc
     9121 gctatgggtg ttactccagc tctcttggtt gtaactcgtg gtaaattgct ccgtatgatt
     9181 atcttcggaa cactcttgtt gccactcttc cttctttcag gtacacttat tgcaccattt
     9241 gcaacagaac ttgctaaagg tgtaggtgcc ttcccagaag gtgtgagcca aactcaattg
     9301 attactcact ctactcttga aggaccaatc gaaaaacttc ttggttggac aattggtaac
     9361 actacaactg gtgatatcaa agcaatcctt ggtgcagtag tcttccttgt attctatatc
     9421 ggtatctttg cttggtacag aaaacaaatg atcaaacgta acgaagagta cgcagcaaaa
     9481 gcaaaataat gcgctcctat aaaatataaa cttaatgaaa atcaaagagc aaactaggaa
     9541 gctagccgca ggttgctcaa aacacagttt tgaggttgta gataa
//
LOCUS       DAVKXA010000066         9040 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKXA010000066 DAVKXA010000000
VERSION     DAVKXA010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.066"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..740)
                     /locus_tag="VW883_001906"
     CDS             complement(<1..740)
                     /locus_tag="VW883_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV0274987.1"
                     /translation="MLKTQEIADKYGITRQTLNNWMQKGIISQPRKNNRSAYEWEEEN
                     EKEIVRVISEEIPAKYYVSNKETLKIGNRRYLGSKQKMLDFILKTVSENIGSIDSVAD
                     IFGGTGVVADLFRKQNKKVIVNDILYSNFISFQTWFSNEDVDIHKVSHIIDELNNLSP
                     KKGYVSKNFGGAYFSEENAGKIDSIREEIEKYKSGNQREYFMLLTSLLYAMDKVANTV
                     GHYDAYRKKMDYCKEIYLRVPEYNENNQ"
     gene            complement(962..1339)
                     /locus_tag="VW883_001907"
     CDS             complement(962..1339)
                     /locus_tag="VW883_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0274988.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            1411..2715
                     /locus_tag="VW883_001908"
     CDS             1411..2715
                     /locus_tag="VW883_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0274989.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQENQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2728..3534
                     /gene="yidA"
                     /locus_tag="VW883_001909"
     CDS             2728..3534
                     /gene="yidA"
                     /locus_tag="VW883_001909"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0274990.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELFTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(3589..3660)
                     /locus_tag="VW883_001910"
     tRNA            complement(3589..3660)
                     /locus_tag="VW883_001910"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3625..3627),aa:Arg,seq:cct)
     gene            complement(3702..4049)
                     /gene="rplS"
                     /locus_tag="VW883_001911"
     CDS             complement(3702..4049)
                     /gene="rplS"
                     /locus_tag="VW883_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0274991.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(4168..4497)
                     /gene="crcB"
                     /locus_tag="VW883_001912"
     CDS             complement(4168..4497)
                     /gene="crcB"
                     /locus_tag="VW883_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0274992.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(4491..4865)
                     /gene="crcB"
                     /locus_tag="VW883_001913"
     CDS             complement(4491..4865)
                     /gene="crcB"
                     /locus_tag="VW883_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0274993.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDAVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(4862..5128)
                     /locus_tag="VW883_001914"
     CDS             complement(4862..5128)
                     /locus_tag="VW883_001914"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0274994.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(5244..5687)
                     /locus_tag="VW883_001915"
     CDS             complement(5244..5687)
                     /locus_tag="VW883_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0274995.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            5791..6726
                     /locus_tag="VW883_001916"
     CDS             5791..6726
                     /locus_tag="VW883_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0274996.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            6780..7064
                     /locus_tag="VW883_001917"
     CDS             6780..7064
                     /locus_tag="VW883_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0274997.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(7121..7699)
                     /locus_tag="VW883_001918"
     CDS             complement(7121..7699)
                     /locus_tag="VW883_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV0274998.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(7674..8687)
                     /gene="efeB"
                     /locus_tag="VW883_001919"
                     /pseudo
     CDS             complement(7674..8687)
                     /gene="efeB"
                     /locus_tag="VW883_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            complement(8690..9040)
                     /locus_tag="VW883_001920"
                     /pseudo
     CDS             complement(8690..9040)
                     /locus_tag="VW883_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         2737 a         2070 c         1614 g         2619 t
ORIGIN      
        1 ttctgattgt tttcattata ctcagggact cttaaatata tttccttgca ataatccatt
       61 tttttcctat aagcgtcata atgacctaca gtattagcca ctttatccat agcgtacaat
      121 agactggtta gtaacatgaa atactctctc tgattacctg atttatattt ttcaatttct
      181 tcacgaattg agtcaatctt tccagcattt tcttcagaaa agtaagcacc accaaaattc
      241 ttagaaacat agcctttttt aggggataaa ttatttaatt catcaattat atgagaaact
      301 ttatgaatat ctacatcctc attcgaaaac caagtttgaa aggaaataaa gttgctatag
      361 agtatatcat tcactataac ttttttattc tgttttctaa ataagtctgc aacaacacct
      421 gttccaccaa atatatccgc cacactatcg atacttccaa tattttctga tactgtcttc
      481 aatatgaaat caagcatctt ttgtttactt cctagatagc gtcgatttcc aatttttaat
      541 gtctctttat ttgaaacata atattttgca ggaatttctt ctgaaatcac tctcacaatc
      601 tctttttcat tttcttcttc ccattcataa gcagaacgat tattttttcg aggttgagaa
      661 attattcctt tttgcatcca attattcaat gtctgtcttg ttataccata tttatcggca
      721 atttcttgtg ttttcagcat ctaggcatcc atctcctttt acagtaatga gtataccata
      781 tttgagagga ttatccaacc aatagtcttc ggtaaaataa agagaaagag actagtacaa
      841 aactaatctc tgtgtacata acaatataac tgctgtatga aatttggata ttatccctaa
      901 tctaccacac taggaagccg atccaagaag atagatagct aaatttgaaa aagacatgag
      961 cctagcccca agtaatttcc aattgatagc tggcaaaggg atgtccctct tgattttgta
     1021 gttgataatc tagttcaatc ttttgcccat ccacttgata acgattcgtt tggataataa
     1081 actcctgcat acccataggt gtgggaatat aggctaaact atcactatcc tttagaaagc
     1141 gcataatggt cttgggattg gaaaatcgac tcatcacaag ttcttgacca tgaaatttaa
     1201 tcactacttt ttccttttcc tcattataga aaagcaggta gctataatct cctttttcat
     1261 gcacttccac atcataaagc tggtcaatca cttccaactg ctcatcaaac tgaattgtat
     1321 ttcgcatccg aatcttcaca tcaggccctc tttcttgtct cttgtcctac tattttacca
     1381 aaaagagcag gattttgcta taatggtcat atgaacgaaa aagtattccg tgaccctgtt
     1441 cacaactaca tccatgtcaa taatcaaatc atctatgact tgattaatac aaaagaattt
     1501 cagcgtttgc gccggatcaa acaactggga acttccagtt ataccttcca cggtggagaa
     1561 cacagtcgct tctctcactg tctaggagtc tatgaaattg cacgacgcat cacagagatt
     1621 ttcgaagaaa aatatcctga ggaatggaat cctgccgagt ctctcttgac catgaccgct
     1681 gctctcctac acgaccttgg gcatggtgcc tactcccata cttttgaaaa tctctttgat
     1741 acagaccatg aagccattac tcaggagatt attcaaaatc ctgagacaga gattcaccaa
     1801 gtcctgctac aagtggcacc tgatttccca gaaaaggtgg ccagtgtcat tgaccatacc
     1861 tatcctaata agcaggtcgt gcagctcatt tctagtcaga ttgacgcaga tcgcatggac
     1921 tatctcttgc gcgactccta ttttacagga gcatcctatg gggaatttga cctgactcga
     1981 atcctccgag tcattcgtcc tatcgaaaat ggtatcgcct ttcagcgcaa tggcatgcac
     2041 gccatcgaag actacgtcct cagtcgctac cagatgtaca tgcaggttta tttccacccc
     2101 gcaacacgcg ccatggaagt tctcctacag aatcttctca aacgcgccaa ggaactctat
     2161 cctgaggaca aggatttctt tgcccgaact tctccacacc tcctgccttt cttcgaaaaa
     2221 aatgtgacct tgactgacta tctggctctg gatgatggcg tgatgaatac ctacttccag
     2281 ctttggatga ccagtcctga caagattctt gcagatttat cgcatcgctt tgtcaaccgc
     2341 aaggtcttta aatccattac cttttcacaa gagaaccaag accaactcgc cagcatgaga
     2401 aaattagctg aggatatcgg ctttgatccc gactactaca ctgccattca taagaacttt
     2461 gacctccctt atgatatcta tcgtcccgaa tctgaaaacc cacggacaca gattgagatt
     2521 ttacaaaaaa atggagaact ggccgaactc tctagcctgt ctcctatcgt ccaatccctt
     2581 gctggcagtc gccacggaga taatcgtttc tatttcccta aagaaatgtt agaccaaaac
     2641 agcatcttcg caagcattac ccagcaattt ttacacttga ttgagaacga tcattttacc
     2701 ccaaataaaa actagaagag gaaatttatg agtattaaac taattgccgt cgatattgac
     2761 ggaaccctag tcaacagcca aaaggaaatc actcctgaag tcttttctgc catccaagat
     2821 gccaaagaag ctggtgtcaa agtcgtgatt gcaactggcc gccccatcgc aggtgttgcc
     2881 aaacttctgg acgacttgca gttgagagac caaggtgact atgtggtgac cttcaatggt
     2941 gcccttgtcc aagaaactgc tactggccat gagattatca gcgaatcctt gacctatgag
     3001 gattatctgg atatggaatt cctcagtcgc aagctcggtg tccacatgca tgccattacc
     3061 aaggacggta tctatactgc aaatcgcaat atcggaaaat acactgtaca cgaatcaacc
     3121 ctcgtcagca tgcctatctt ctaccgtacc cctgaagaaa tggctggcaa agaaattgtt
     3181 aaatgtatgt ttatcgatga accagaaatt ctcgatgctg cgattgaaaa aattccagca
     3241 gaattttacg agcgctactc catcaacaaa tctgctcctt tctacctcga actctttaca
     3301 aagaatgtag acaagggttc agccattact cacttggctg aaaaactcgg attgaccaaa
     3361 gatgaaacca tggctatcgg agacgaagaa aatgaccgtg ccatgctgga agtcgttgga
     3421 aaccccgttg tcatggaaaa tggaaatcca gaaatcaaaa aaatcgccaa atacatcacc
     3481 aaaacaaatg acgaatccgg cgttgcccat gctattcgta catgggtact gtaaaaggaa
     3541 agaatagact aaaaccgctc agttgagcgg tttttgatgt ctaattactg ccccctgcag
     3601 gaatcgaacc tgcaactact ccttaggagg gagttgttat atccattgaa ctaagggagc
     3661 tagataaaaa ctctgctgaa aagcagagtt ttttagtcga attaacgacg gatttctttg
     3721 atacgagctg ctttaccttg aagagcacgc aagtagtaca atttcgcacg acgtacttta
     3781 ccgtaacgaa caacttcgat tttttcaaca cgtggagtgt ggattgggaa gatacgctca
     3841 acacctacac cgttagagat tttacgaact gtgtagtttt ctgagattcc agcaccttta
     3901 cgtgcgataa caacaccttc aaaaatctgg atacgttcac ggttaccttc gacaactttc
     3961 gcatgtacac gaacagtgtc accaggacgg aatgatggga tatctgtacg aagttgacct
     4021 tcagtcaagc tttggattaa tggattcatt ttattctcct atctttgtca atcttgagga
     4081 aacttcctca gcggataaac tgtatttttg tgcgtccatc acacacaaga tacagtctac
     4141 caaattttca caaaaaagta aagaaattta tagcaaaatt cctaaaaaaa tcgcaaccaa
     4201 accacctatg taagtcaaag tcaggtaaga ataaaagacc ttcttatcac ttagcagtct
     4261 ttgaagttcg tcattcaagg tcgaaaaagt tgttaaaccg ccacaaaatc ctgttgctag
     4321 aatagcatat acttccttag actctacatg attgtagaat actccaatta aaaaacaacc
     4381 taaaagatta gctatgagcg ttccgagtgg caatttagaa gcttgattgt agcgggaaaa
     4441 gaaataccgt acgagtgctc ccaagccaca ggcgattgca agatagacga ttaccatttc
     4501 ttcctcccca aatagtaagc taaaagcagg cctccaccga tactcaaaag caaatacagt
     4561 atcaaactaa gataacgccc tgtatccagt aatttcacag catcaagcat gagactagaa
     4621 aaggttgtta aacctccgca aaaacctgta cccagtgcta aaatcaagcc cttactagtc
     4681 cccttataga ccagatagcc cttgacaaga aaaatcaagc agaaaattcc caaatagttg
     4741 acaaagagag tgccccaagg aaagtctgga ctggctggta accaggtgga aactagatat
     4801 cggacaagtc cgcccaacat agcagctaga aaaattccta gcggataaaa ttgttctttt
     4861 ttcatttgat attttgatcc tgataatcac gcgaacgttt gagtatgtcc gaaaaagtcg
     4921 ctacaatagt ctcctgatag cgcttgtcct ctacacgact cctaaccttt tcaaaaataa
     4981 cttcttctct cttagtatct aaaatcggtt tacctgaagc tttcttataa gcaaccaccc
     5041 cctcaactaa atgcattcgt tcttctaaca gtttgacaat ttggtcgtcg atttgatcga
     5101 tttcttgacg aataatatct aaatccatac agtctcctcc tttatttgaa ttattgtatc
     5161 aaaaagccat caattaggct agtaaaatcc caactctcga taagaaaaat gcactgattg
     5221 attacatcag cgcactttta tgcttatcct actttagcag ccaattcttc tgcgaattgt
     5281 tccaagcgtt caatatcttc ttcctcggca gaaagatcaa ctttaacaca ctctgaacct
     5341 ttttctgctc ctgttgacac aaagacacgg tcaaagtcat caacagcctt acagaattca
     5401 tcgtagaagg tatctcctga gccgaccact ccgtagattt tgccattcaa gttgagatct
     5461 gctaggtctt cgtagaagtc catcatctca tctggcaatt caccatcacc ataagtatag
     5521 gtcgcaacga tagcgatgtc tgcttccaag aagtctgaag cgtcaacagt tgtacattca
     5581 tcaacatcaa catccaagcc caagtcacgt aatttgtctg ctacaatatc tgcaatttct
     5641 tcggtattac cggtcatact ggcaaataca atttttgcta atgccatatc gtcctcctca
     5701 atttatcttt ctccattata tcacatcttt ttcattttaa aaataaaaat tcttgtgcta
     5761 caatgaaatg agaaagaatt gaggttattt atggagattt gccaacaaat tttagaaaaa
     5821 attaaagaat acgacaccat tatcattcat cgtcatatga aaccagaccc tgatgccttg
     5881 ggaagtcagg tgggattgaa agccttgctg gaacatcatt tcccagaaaa aaccatcaaa
     5941 gccgtcggtt ttgatgaacc aactcttact tggatggctg agatggatct tgttgaagat
     6001 agagcctacc aaggcgcact tgtcatcgtc tgtgatacag ctaatactgc tcgtatcgat
     6061 gataagcgct atagtcaagg tgattttctc attaagattg accaccatcc aaatgatgat
     6121 gtatacggtg acctgtcttg ggtcgatact agttcaagta gcgctagcga gatgattacc
     6181 ctatttgccc aaacaaccca actagccttg gcagatcgcg atgctgagtt gctctttgca
     6241 ggaattgtcg gtgatacagg tcgcttcctc tacccttcta ccactgcacg gactcttcgc
     6301 ctggctgctt atttgagaga acataacttt gactttgcgg ctctcactcg caaaatggac
     6361 actatgagct acaaaattgc taaactgcaa ggctacatct acgaccatct ggaagtggat
     6421 gaaaatggtg ctgctcgcgt tatcctgagt caagaagtct tgaaacaata caatgtaacc
     6481 gatgctgaaa ctgcagccat tgtcggtgca cctggacgca ttgacagagt gagtctctgg
     6541 ggaatttttg tcgaacaggc tgatggccac taccgagttc gcttacgcag taaaatccat
     6601 cctatcaatg aaatcgccaa ggagcatgat ggtggaggcc accctctagc aagtggtgct
     6661 aattcctata gcctagaaga aaacgaaatc atctaccaaa agttaaaaaa cttgcttaaa
     6721 aactgataaa atacttgcca aacttttcag aatctgatag actagtatgg taacaatcta
     6781 tggctcgcaa agagaccatg gcagaaagga aatattgcaa aatgaaaaaa gatatccatc
     6841 cagaatatcg cccagttgtc ttcatggaca caactactgg ttaccaattc cttagcggtt
     6901 caacaaaacg ctctaacgaa acagttgagt tcgaaggcga aacttaccca ttgatccgtg
     6961 tggaaatttc atcagactca cacccattct acactggacg tcaaaagttc actcaggcag
     7021 atggacgcgt ggatcgtttc aacaaaaaat acggtctcaa ataatgataa gagaacagtt
     7081 tcggctgttc ttttttgttt cttgaaatca actgctgttt tcatgttcca gactcatctg
     7141 taggttcggt ttccatgcta ctaggcagga aggaaatagc tgtttcaaca cgtccataat
     7201 gagctgtact attgtcacga accacacttt cattgatggt ccaagtggaa ttcattttct
     7261 taaaagcttc tcggactttt tccaaatctt tggaggcaat ggcctgttct aaggtttcaa
     7321 aacgaggact tagacggttt accaattttt ccttttccgc atctaggtca acaggatttt
     7381 gttctttttc aaaagctaat agagctgagg aaatttcggt gagtttggct tcagtaatat
     7441 ctccagatag agctaacttt tccttaacaa tcttaccaac ctcagaatcc ttattttcta
     7501 ctctttcgaa gtctgatgcc atcttcgtaa cgagtttctg ggtctcagtc tgaccaccat
     7561 ttttaaccgt tttggatgca tctgtgattt tcacaaagaa aaaactcaag ctttcttggg
     7621 cacctgctgg ggaaagaatt aaaaatgaca aagctaaaac tagtaaccag cttttagcct
     7681 tccaataatt tctgaccaat gtagcctcct ttctccacac caccaaagca agtaaaaagt
     7741 ccactaccta tgtgagtgat gtattcattc atcttatcag tagcacctag gttagtttga
     7801 accttaacaa agttatcagg atccttctgg aaagaaatga agagcaatcc cgtatcaaac
     7861 tgaccagtct tttcatcaat gccatctgag taagaataag aacgacgtaa aagtggctta
     7921 tccacttctt tggccaaaca aacatgcgaa tcatcaggta agagactcaa atccacttca
     7981 tcaaactcat ttttcttacc aaagggggca ccgctttcct tgtaacgacc aaaggtattt
     8041 tcttgttctt cgagactagt gcggtcccag gtctctaaaa acatctgaat ccgacgaact
     8101 gccatataag aaccattttc catccagtcc ttactatcag cccagataac gcggtcaaag
     8161 tcttgctcct tggttggatt tgctgttcca tccttaaaac caaagaggtt ccacggagtc
     8221 tccattcgat ccccgatagc tgcaaatcca gactgactcc aacgaagggg caccgcattt
     8281 ctccccttac ggatgagatt gcgaatagcg tgaaaggcaa tttgctcatc atctgcacaa
     8341 gcatgaatca caatatctcc accagtatat ttttcacgta attgctcctt aggaaataga
     8401 ggtaaatccc tgaacagtcg agggcgcttg ttttccaagt tcatcctttt caagaaactt
     8461 gcagatacac caaaagtcag cgtcaaacga tgaggattga gcccaacttt ctcaccagta
     8521 tcgctcggag gaaagagagc attctgtcca tcttttttaa ccaattcccc ctcgaccaac
     8581 ttggcactat aatccgtcca atccttgaat agctggataa ttttatctct atccgtcgta
     8641 tgcaggtcca agacaacaaa atagatattc ttttgcatgg gcgtactatt tggtacatca
     8701 agcgaacctt atgaaaaggt ctactggttt taaagcgctt tcttgtcttc ttgaattgag
     8761 attttatttt tagacgcgac aatggtttga gcgtctgctt tcctaggatg ttctggacgt
     8821 ggtgtaatat ttcgccaacc atggcgcttc aacagttgat agaaggcatc acgtgtgtag
     8881 gaacgaccta actccttttt ataagcctga aataaggcat caattgtaac aaattctcct
     8941 gcctctgtag ccttcaaatg acgggcaaga aaggctttct cttcctcaac tgtcatatat
     9001 gcatggttac gaccaccacg tgtttcttga aggagagagt
//
LOCUS       DAVKXA010000067         8957 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKXA010000067 DAVKXA010000000
VERSION     DAVKXA010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.067"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            63..527
                     /locus_tag="VW883_001921"
     CDS             63..527
                     /locus_tag="VW883_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0274999.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            684..1109
                     /gene="lacA"
                     /locus_tag="VW883_001922"
     CDS             684..1109
                     /gene="lacA"
                     /locus_tag="VW883_001922"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0275000.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1140..1655
                     /gene="lacB"
                     /locus_tag="VW883_001923"
     CDS             1140..1655
                     /gene="lacB"
                     /locus_tag="VW883_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0275001.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1666..2595
                     /locus_tag="VW883_001924"
     CDS             1666..2595
                     /locus_tag="VW883_001924"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0275002.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLTKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2597..3577
                     /gene="lacD"
                     /locus_tag="VW883_001925"
     CDS             2597..3577
                     /gene="lacD"
                     /locus_tag="VW883_001925"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0275003.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3811..4647
                     /locus_tag="VW883_001926"
     CDS             3811..4647
                     /locus_tag="VW883_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0275004.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4683..5000
                     /locus_tag="VW883_001927"
     CDS             4683..5000
                     /locus_tag="VW883_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0275005.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5000..6691
                     /locus_tag="VW883_001928"
     CDS             5000..6691
                     /locus_tag="VW883_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0275006.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6900..8306
                     /gene="lacG"
                     /locus_tag="VW883_001929"
     CDS             6900..8306
                     /gene="lacG"
                     /locus_tag="VW883_001929"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0275007.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGKKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8451..8615
                     /locus_tag="VW883_001930"
     CDS             8451..8615
                     /locus_tag="VW883_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0275008.1"
                     /translation="MESLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEWDTISF
                     DSDFMPFQQS"
BASE COUNT         2826 a         1584 c         1841 g         2706 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa agcaaaaaat
      541 aaataacaaa aacaaacaca aactgttgac ttcttcaaac aatagtagta tattatgttt
      601 gtgaggacta attgactgtt ttttaaagac agccaataca ctgctggaat ccagcataga
      661 aaaaataaaa aggagtatac aatatgtcta ttgttatcgg tgcagatgct gcaggtttga
      721 gattgaaaga agttgtgaaa gacttcttag aaaaagaaaa cttccacctt gtggatgtta
      781 cagctgaagg tcaagacttt gttgatgtga ctctcgctgt tgctgcagaa gtaaacaaag
      841 aagaacaaaa ccttggtatc gtgattgatg cttatggagc tggtccattt atggttgcaa
      901 ctaagatcaa aggaatggtt gctgcagaag tatctgacga acgttcagct tatatgactc
      961 gtggccacaa caactcacgt atgatcacta tgggggcaca acttgttggt gatgaattgg
     1021 ctaaaaatat cgctaaagga tttgttaacg gtaaatacga cggtggtcgt caccaaatta
     1081 gggtcgacat gttgaacaaa atgggctaat tagattatag taagaaaggt aagttaaaaa
     1141 tgagaattgc aattggatgt gaccacatcg taacagatga aaaaatggcg gtttcagaat
     1201 ttttgaaatc aaaaggatat gaagtcattg actttggtac ctatgaccat acacgtactc
     1261 actacccaat ctttggtaaa aaagtagggg aagcagtaac tagtggtcaa gctgatctcg
     1321 gggtatgtat ctgtggtact ggtgttggta tcaacaacgc tgtaaataaa gttccaggta
     1381 ttcgttctgc cttggttcgt gatatgacaa cagcccttta tgctaaagaa caattgaacg
     1441 ccaacgttat cggttttggt ggtaagatta ctggtgaatt gcttatgtgt gatatcatcg
     1501 aagctttcat tcatgctgaa tacaaaccat ctgaagaaaa caaaaaattg attgcgaaaa
     1561 ttgaacacct tgaaagtcac aatgctcaac aaacagacgc aaacttcttc actgaattcc
     1621 ttgaaaaatg ggatcgcgga gaataccacg actaagaggt aacctatgat tttaacagtt
     1681 acaatgaacc catccattga tatttcctat cccttggatg agttgaagat tgatactgtc
     1741 aatcgtgtgg tggatgtaac caaaacggct ggtggtaagg gactcaatgt tacccgagta
     1801 ctttcagaat ttggcgattc tgttcttgct actggtttag tgggtggcaa acttggtgag
     1861 tttttggttg aacatatcga taatcaagta aagaaagatt tcttctcaat tcagggagaa
     1921 actcgtaact gtatcgctat tctccacgga gacaaccaaa cagaagttct tgaaaaaggt
     1981 cctgaagtat tggaacagga aggtcaagac tttttggaac atttcaaaaa actcttggag
     2041 tcagttgaag tagtggccat ctcaggtagt ctgccagctg gccttccagt tgattactat
     2101 gcgagcttgg tagaacttgc taatcaagct ggcaagcctg tagtcttgga ctgctcaggt
     2161 gcagcacttc aggctgttct tgaatcaccc cataaaccaa cagtcatcaa accaaataat
     2221 gaagaattgt ctcagcttct tggaagagaa gtttctgagg atttggatga attaaaagaa
     2281 gtacttcaag aacctttgtt tgcagggatt gaatggatta tcgtttcact tggtgccaac
     2341 ggtacttttg ccaaacatgg tgacactttc tacaaggtag atattcctag aattcaggtg
     2401 gtaaatcctg ttggatctgg agactctact gtggcaggaa tttcttcagg acttcttcac
     2461 aaagaatcgg atgcagaatt actcaccaag gcaaatgtcc ttggtatgct caatgctcaa
     2521 gaaaaaatga ctggtcatgt caacatggcc aactatcaag ttctatatga tcaattaata
     2581 gtaaaagagg tataaaatgg ctttaacaga acaaaaacgt gtacgcttag aaaaactttc
     2641 tgatgaaaat ggtatcatct cagctcttgc atttgaccaa cgtggtgctt tgaaacgcct
     2701 catggctcaa caccaaacag aagaaccaac tgtggcccaa atggaagaac ttaaagtctt
     2761 ggtagcagat gaattgacta aatacgcttc atctatgctt cttgaccctg agtatggact
     2821 tccagcaact aaagctcttg atgaaaaagc tggtcttctc cttgcttatg aaaaaacagg
     2881 ttatgacaca acaagcacaa aacgcttgcc agactgcttg gatgtctggt ctgcaaaacg
     2941 tattaaagaa gaaggtgcag atgcagttaa attcttgctt tactatgatg tagatagctc
     3001 agacgaactc aatcaagaaa aacaagccta catcgaacgc atcggttctg agtgtgtggc
     3061 tgaagatatc ccattcttcc ttgaaattct tgcttacgat gaaaaaattg cggatgcagg
     3121 ttctgtagaa tacgcgaaag taaaaccaca caaagttatc ggcgctatga aagtcttttc
     3181 agacccacgc tttaacattg atgtcttgaa agttgaagtt cctgttaaca ttaaatatgt
     3241 tgaaggcttc gctgaaggtg aagtagttta tacacgtgaa gaagcagcag ccttcttcaa
     3301 agcgcaagat gaagcaacga acttgccata catctacttg agtgctggtg tatcagctaa
     3361 actcttccaa gatactcttg tatttgctca tgaatcaggt gcaaacttta acggagttct
     3421 ttgtggccgt gctacatggg cagggtcagt tgaagcttac atcaaagatg gtgaagcagc
     3481 agctcgcgaa tggcttcgca caactggatt tgaaaacatt gatgagctca ataaagttct
     3541 tcaaacaaca gcgacttcat ggaaagaacg tgtgtaagaa agtcctccta gtttaggaac
     3601 atgaatctaa aaaaatttaa aaaaagttgt atgtaaaggt ttacaaaata acttacttgt
     3661 gctatactta aatcacaagt taatacaagg tgagtgttac taagtaatat taggcatgat
     3721 cacaggtgaa ttagaaatca gctgattttc tagttcattt gtggtcattt tttgtactta
     3781 tataccttta agatataaaa ggaggttgac atgtatcgaa ttctaaatcc aatgaatcac
     3841 aatgtctcgc ttgtcagaaa tgataaggga gaagaggtga ttgtaattgg taaggggatt
     3901 gcattcggaa agaagaaggg ggatttgatt gctgaaaatc aggttgagaa aatctttcgg
     3961 atgaagaccg aagagtccag agaaaacttt atggctcttc tcaaagatgt tccgcttgat
     4021 tttatcacag tgacctatga aatcattgat aagctatcaa agaaatatca ttatccgatt
     4081 caagagtatc tctatgtaac cttgacagat catatttact gttcttatca agctctaact
     4141 caaggaaggt acaaggatag taatctgcca gatatttccg ctaagtatcc tgtcgctttt
     4201 caaatcgcaa atgaagcttt tgaaatttac cgtcagaagc tagcagatca ttttcctgag
     4261 gacgaaatta ttcggattgc ttatcatttc attaatgctg aaggtgaaaa tgaagtggaa
     4321 cttgtggagt cgattgataa gaggaaagaa attctcagga atgttgaaga agttttaacg
     4381 gactatgcaa ttcaacgaac taaaaagaat aaccatttct atgatcgctt tatgatccat
     4441 ttgaattatt tcttggatta tttagacaga tctagagatg ataaccaatc acttctggat
     4501 atggaagatc atattaaaca atcctatcca aaagccttcg agattggttc caagatctat
     4561 gatgtgatta cgcaacatac gggtcttgat ttgtataaaa gtgaacgagt ttatctagtt
     4621 ctacatatcc aacgtttatt gtcataaaaa tttatttaaa actatataag gagaattcta
     4681 tcatgaatag agaagaagta acattgttag gttttgaaat cgtagcctat gctggcgatg
     4741 ctcgttcaaa actattggaa gccttgaagg ctgctgaagc tggtgatttt gaaaaagcgg
     4801 acgctctggt agaggaagct ggtagctgta ttgcagaggc tcaccacgcg caaacaagtc
     4861 tattgactaa ggaagcttca ggtgaggact tggcttatag tgtaaccatg atgcatggcc
     4921 aagaccactt aatgacaact atcttgttaa aagatttgat gcatcattta attgaactct
     4981 acaagagagg agttaaataa tgaataaact aattgcattt atcgagaaag gaaagccttt
     5041 ctttgaaaaa ctatctcgta atatctatct tcgtgctatt cgtgatggtt tcattgcagg
     5101 tatgcctgtt attctcttct caagtatctt tatcttgatt gcctttgtac caaactcatg
     5161 gggctttaaa tggtctgatg aagttgtagc ctttctgatg aaaccttata gctattctat
     5221 gggtattctg gctctcttgg tagctggtac aacagctaag tcattgactg actcagtaaa
     5281 ccgtagcatg gaaaaaacca atcaaatcaa ctatatgtca acattgttgg cagcaattgt
     5341 tggtttgttg atgttggcag ctgatcctat cgaaagtggt ctagctactg gattcttggg
     5401 gacaaaaggt ttgctttcag ccttccttgc tgccttcgtt actgtagcca tctataaggt
     5461 ttgtgttaag aacaacgtca ctattcgtat gcctgacgaa gttccaccaa atatctcaca
     5521 agtctttaaa gatgtgattc cattcactct ctcagttgtt tcactttatg ctcttgattt
     5581 actagctcgt cattttgttg gtgcaagcgt agctgaatca atcggtaaat tctttgcacc
     5641 actcttctca gcagcagacg gataccttgg tattaccatt atctttggtg cctttgcctt
     5701 cttctggttt gtgggtattc atggtccatc tattgttgaa cctgctatcg cagcgattac
     5761 ctatgcaaat gctgaagtca acttgaacct tctccaacaa ggtatgcatg ctgataaaat
     5821 ccttacttca ggaactcaaa tgtttatcgt tactatggga ggtactggtg cgacactggt
     5881 tgttccattc atgttcatgt ggttaacaaa atcaaaacgt aaccgtgcaa tcggacgtgc
     5941 ttcagtagtt ccaactttct ttggtgtaaa tgaaccaatc ttgtttggtg caccacttgt
     6001 attaaatcca atcttcttca ttccatttat ctttgctcca atcgcaaacg tatggatttt
     6061 caaattcttt attgaaactc ttggaatgaa ctcattcact gctaatctac catggacaac
     6121 tccagctcca ctaggtctag ttcttggaac taacttccaa gtgctatcat tcattcttgc
     6181 tgcccttcta atcgtggttg acgttgtcat ttactatcca ttccttaagg tctatgatga
     6241 acaaattctt gaagaagaac gttcaggtaa gtctaatgat gaattgaaag aaaaagttgc
     6301 tgcaaacttc aacactgcaa aagcggatgc tattcttgaa aaagcgggtg tcgatgcagc
     6361 acaaaatacc atcactgaag aaacaaatgt cctcgttctc tgtgcaggtg gaggaacaag
     6421 tggtctcctt gcaaatgctt tgaataaggc agcagcagaa tacaatgtcc ctgtgaaagc
     6481 agcagcaggc ggctatggtg ctcaccgtga aatgttacca gagtttgatc ttgttatcct
     6541 tgcccctcaa gttgcttcaa actttgaaga tatgaaagca gaaacagata agctcggtat
     6601 taaactagcg aaaacagaag gcgctcaata catcaaatta actcgtgatg gaaaaggtgc
     6661 tcttgcattc gtacaagcgc aattcgatta aggctagaga ctctgaaata gtctcctatc
     6721 gttacggaaa tcgctatggc gaatttccta ttattaattc gtcggtaaaa agatatcgtt
     6781 tttacctcct catgtcacaa ttcggtgact tggtacaaga agtgagatgg agaaggatgg
     6841 ctcactgact cctctcctct cacttttact ttatttaaat caagaaatag gtgaaaaaaa
     6901 tgacaaaaac acttccaaaa gactttattt ttggtggcgc aacagctgct tatcaagcag
     6961 aaggtgctac acatactgat ggaaaaggac cagttgcttg ggataaatat cttgaggata
     7021 actactggta cactgccgaa ccagctagtg atttttacaa tcgatatcca gttgacctca
     7081 agctagcaga agagtatggt gtcaatggta ttcgaatttc tattgcttgg tcacgtattt
     7141 tcccgactgg ttacggccaa gtaaatgcta aaggtgttga gttttatcat aatttatttg
     7201 cagagtgtca caaacgtcat gttgagcctt ttgtaactct tcatcacttt gacacgccag
     7261 aagctctcca ctcaaatgga gacttcttaa accgtgaaaa tatcgaacat tttgtagact
     7321 acgctgcctt ctgttttgaa gaatttccag aagtaaacta ttggacaacc tttaatgaaa
     7381 ttggaccaat cggtgatggt caatatttag ttggtaaatt ccctccagga attcagtacg
     7441 accttgccaa agtcttccaa tcgcaccaca atatgatggt gtctcatgca cgtgctgtaa
     7501 agctatataa agataaagga tataaagggg aaattggtgt tgttcacgcc ctgcctacta
     7561 aatatcctct agatcatgaa aatccagcag atgttcgtgc agctgagttg gaagatatca
     7621 tccacaataa attcatctta gacgcaactt atctaggtcg ctattcagct gaaaccatgg
     7681 aaggtgtcaa ccatatctta tcagtcaatg gtggtagttt ggatcttcgt gaagaagatt
     7741 ttacagcatt agaagctgca aaagacttga atgatttcct aggaatcaac tactatatga
     7801 gtgactggat ggaagccttt gatggagaaa ctgaaattat ccataatggt aaaggtaaaa
     7861 aaggaagctc taagtatcaa atcaaaggtg ttggtcgtcg tgtagctcct gactatgtac
     7921 cacgcacgga ttgggattgg attatctacc ctcaaggttt gtatgaccaa atcatgcgtg
     7981 tgaagaaaga ttatcctaac tacaagaaaa tttacatcac tgaaaatggt ctcggctata
     8041 aagatgagtt cgtcgataac actgtttacg atgatggtcg tattgattac gtgaaacaac
     8101 acttggagat cttgtctgat gcgattgcag atggagctaa tgtaaaaggt tacttcattt
     8161 ggtcattaat ggatgtcttc tcatggtcaa acggttatga gaaacgttat ggtctcttct
     8221 acgtagattt tgaaactcaa gaacgttatc ctaagaaatc agctcactgg tacaagaaag
     8281 tagcggaaac tcagattata gactagtaga attagtcatt agatatagaa ttttagtgag
     8341 tccaaaagat gttcaaagat gttcaaagat tttatccaat ctatttatga aaaagtttat
     8401 attataaatt tcgaaaaatg ctctcaaata ccgtgtttga cgagtgaaga attgaaagtc
     8461 ttggaaaatg gtatgtctcg actggtaaag aatggatttg tcattcagat gatgagctgg
     8521 aagaatttaa aaatctattt ttaaatttta tcaatcctga agaatgggat actatctcct
     8581 ttgattcaga ttttatgccg tttcaacaat cgtaaccaat ttctcaaaaa agttaaatct
     8641 tatatttagt actctgtaaa actcttatct aatcacgttg cttatactca atgaaaatca
     8701 aagagcaact ttaaactagg aagcgagtcg cagatttctc aatgtatagc tttgaggaat
     8761 tgggcaaaaa gtctttgata tagaaaaaag catagtatca ggtgtttcaa cacctgatac
     8821 tatgcttttt attgtgggaa gatttacttt ttttcttctg aaattgagtt gttacccagg
     8881 ctctttcagt ttattaaggc ttgatgactt taatgtgttt agatagctta aaaaggattg
     8941 aatcacttag tttagaa
//
LOCUS       DAVKXA010000068         8344 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKXA010000068 DAVKXA010000000
VERSION     DAVKXA010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.068"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..220
                     /locus_tag="VW883_001931"
     CDS             <1..220
                     /locus_tag="VW883_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0275009.1"
                     /translation="GCLDMVVIQKQNEIEELSTNIEKKIMNYIFEDDGNVSEVIGALD
                     IIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            233..1708
                     /gene="galT"
                     /locus_tag="VW883_001932"
     CDS             233..1708
                     /gene="galT"
                     /locus_tag="VW883_001932"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0275010.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEENAIADYHLEWADQLKEKYPRINKEEVN
                     NVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1721..2731
                     /gene="galE"
                     /locus_tag="VW883_001933"
     CDS             1721..2731
                     /gene="galE"
                     /locus_tag="VW883_001933"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0275011.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2911..3570
                     /locus_tag="VW883_001934"
     CDS             2911..3570
                     /locus_tag="VW883_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0275012.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3595..4662
                     /locus_tag="VW883_001935"
     CDS             3595..4662
                     /locus_tag="VW883_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0275013.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4766..5776
                     /locus_tag="VW883_001936"
     CDS             4766..5776
                     /locus_tag="VW883_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0275014.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5788..7479
                     /locus_tag="VW883_001937"
     CDS             5788..7479
                     /locus_tag="VW883_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0275015.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7482..8192
                     /locus_tag="VW883_001938"
     CDS             7482..8192
                     /locus_tag="VW883_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0275016.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2833 a         1149 c         1639 g         2723 t
ORIGIN      
        1 tggatgttta gatatggttg ttatacaaaa acagaatgag atagaagagc ttagtacaaa
       61 tattgaaaag aaaataatga attacatatt tgaagatgat gggaatgttt ctgaagtaat
      121 tggtgcttta gatattattc atcaccttga taaaattgct catactacgc aatcaattta
      181 taaatggata atgtatagaa aatatgggaa cataaattag aaagaaaaat atatgaaaac
      241 aattattgat aattttgttg atagagtaat tgaatacgga atgtataatg aaattgacaa
      301 aatatatgtg aaaaatagag tactagcgtt aataggtgag gagggaactg atcgcatttc
      361 cgatgaaaat gacctgaaac aaataaaaga ttacttagtg gaaatcgcct taaaaaacgg
      421 taaaattaaa gatttaatcg aggaaaagga atgtttagga gcagagttaa tgaatttcat
      481 agttccttta cctagtcgat taaatgatat tttttggagt tcatatgata tatcacctca
      541 agaagcagtt gaagagtttt ataagttaag taaagatagt gattatatta aaacttctgc
      601 tattgctaag aatattgagt ttcgagcatc aactaaatac ggagagctag agattacgat
      661 aaatttgtca aaacccgaaa aagatccaaa aacaattgct gctgaaaaat tagtaaaagc
      721 cactaattat cccaaatgtt tactatgtat ggaaaatgaa ggatatcagg ggcgaataaa
      781 ttatccagca cgttcgaatc atagaattat tcgattgaaa cttggtgacg aagtatgggg
      841 attccaatat tctccctact tatactttaa tgagcatgcg atatttttaa atagtcaaca
      901 tgtaccaatg gctattacct ctaaaacatt tgaacaatta ttggagattg ttgatatttt
      961 gccaggatat tttgctggtt caaattctga tcttcctatc tcaggaggct ccattcttag
     1021 tcataaccac taccagggag ggaaacatat tttcccaatg gaaaaagcaa aatttgagag
     1081 tgaatttcgt tttaaagact ttgaggatgt taatgctggt attgtaaaat ggccaatgtc
     1141 agtaattagg ttacaaagtg aaaataaaaa tcgcttgtta gatttagcta ctaaaattct
     1201 aaataagtgg agagaatatt cagatttaga agtagacatc attgctatga ctgaagatgt
     1261 cccacaccat acggtgactc ctattgctcg taaagtggac gggagatatg aattagatat
     1321 tgttctaaga gataatcata ctactgaaca gtacccagat ggtgttttcc atcctcatca
     1381 agatgtacaa catattaaaa aggaaaatat cgggttaatc gaagtgatgg gacttgcgat
     1441 attaccacct cgtttgaaac cagagttaga agaagtggga aaatatcttt taggagagga
     1501 aaacgcaatt gcggattatc atttagaatg ggccgaccaa ttgaaagaaa aatatcctcg
     1561 cattaataaa gaagaggtta ataacgtagt tcaacacgaa gcaggacaag tgtttgcgag
     1621 agttctggaa gatgcaggag tttataagaa tacaccgtct gggcatgaag cgtttatgag
     1681 atttgttaag tcggttggaa ttaattagga ggaaacccaa atggcaatat tggtaacagg
     1741 cggagctggt tatattggta gccataccgt agtagaatta ctaaatttag gaaaggaagt
     1801 catcattgtc gacaaccttt cgaactctag catcttggtg ctagaccgta ttgaagcaat
     1861 tacaggaata cgtcccgtgt tttacgaatt agatgtttgt gataaacaag cattgagaaa
     1921 ggtatttgaa caagaatcga ttgatgctgc aattcatttt gcaggttata aagctgtcgg
     1981 agaatccgtg caaaagcctg tgatgtacta caaaaataat attatgagta cattggcact
     2041 tgttgaagtg atgtcagaat ttaatgttaa aaagattgtc ttttcttcaa gtgcgactgt
     2101 atatggaatt aacaatcagt cacctctaat tgagacgatg caaacaagtg cgacaaatcc
     2161 ttatgggtat acgaaagtga tgcttgagca aattttaaaa gatgttcatg tggcagattc
     2221 agaatggagt attgcgttgc ttcgttattt caatccaatt ggtgctcatg agtctggttt
     2281 gattggggaa gatccctcag gaattcctaa caacttgatg ccttatattg cacaagtagc
     2341 ggtaggtaag ctatcagagc taagtgtgtt cggaaatgat tatgatacgc ttgatggtac
     2401 tggtgtgcgt gattatatcc atgtagtaga tttagcaata ggacatataa aagctttaga
     2461 aaaagtatct gaaaaaacag atgtttatat ctataaccta ggctcgggag aaggcactag
     2521 tgtattacaa cttgtaaata catttgaaag tgttaataag atccctattc cttataaaat
     2581 agttccaaga cgttcaggag acgttgcaac ttgttatgca aatgcagaca aagcatataa
     2641 ggaattaaat tggaggacaa caaaatcgat tgaagacatg tgtagagata catggaattg
     2701 gcaatcaaaa aatcccaatg gctataattg atgatactgt ctatatgagt gctgtatttt
     2761 gaaaaaatta cttaaccttt taatgaaatg catatttaat gaaagataaa tttaaaaaaa
     2821 tgtttgcaag tgcttgacaa aggaaacggt ttcattgtat aatgtaaaca tgatgacacc
     2881 gatgtcaaat ataaaaaaga aggtctttat atgaaaaact taacaaaaat taagttcaaa
     2941 gagaatgggg aatttaatca tttccctggg aatacagttg tagcaaatct ttatactaaa
     3001 caagatttga tggaagttgt tgatattatt caatcacgtt atagagaatt accatttatc
     3061 gataagttta ctttaactcc aaggaattct attcacatga ctgtaattga attgttgtgc
     3121 catgaaaatc gtgaaacgga gttttggagc agtaatcttc ctctagatac acctttacag
     3181 gaaatacatg attactttgc taaacaactt gaaatttttc cattgttgga tgaagaaatt
     3241 catatgcgta taactgaaat gggaaaacaa aacatactag ttgaacctgc agatgaagct
     3301 tctgcaaaga gattagaaga aattcgtact tatgtctcag aaaaagcagg tgtttgtttc
     3361 cctaatcatg atagatatca attccatatt tcaattgggt atcttcggat tcctctaacc
     3421 gaagaggagg aagaagagtt tactaaagtc agagcagaat taactgaaat tttattagag
     3481 aagattccaa ctattactgt aaaccgtatt gactatactg tatttgaaga tatgagacaa
     3541 tttgttccat atcacgaaaa atttaaataa aataataaaa aaggagaact tatcatgaaa
     3601 aaaatgaaag tttggtctac tgtacttgca acgggagttg ctcttactac acttgctgct
     3661 tgctctggag gttcaaattc tacgactgct tcttcatctg aagaaaaagc tgataaaagt
     3721 caagaattag ttatctattc gaactcagtc tcaaatggtc gtggtgattg gttaactgct
     3781 aaagcaaaag aagctggttt taatataaaa atggttgata tcgctggcgc tcaattagca
     3841 gaccgtgtta ttgctgagaa gaataatgca gttgcagata tggtatttgg aattggtgct
     3901 gttgattcaa ataaaattag agatcaaaaa ttactagtac agtacaagcc taaatggtta
     3961 gataaaattg atcaatcttt atcagataaa gataattatt ataatcctgt gattgttcaa
     4021 ccattagttt taattggggc gcctgatgta aaagaaatgc ctaaagattg gactgaatta
     4081 ggtagtaagt ataaaggtaa atattcaatt tatggtcttc aaggtggtac aggacgggca
     4141 attctagcaa gtatcttagt tcgttacctt gatgaaaaag gagatttagg cgtatcagaa
     4201 aaaggatggg aagttgcaaa agaatacttt gcaaatgcct atactcttca aaaaggtgaa
     4261 agctcagttg ttaaagcgtt agataaagaa agcccaattc aatacggtat gatctggggt
     4321 tctggagcgt taattggaca aaaagaacaa aatgttgaat tcaaagttat gactcctgag
     4381 attggtgtac catttgtaac tgaacaaact atggttttaa gcactagtaa aaaacaagcg
     4441 ttagctaaag aatttattga ttggtttggt caatcagaaa ttcaagtaga atatagtaaa
     4501 aaatttggat ctattcctgc caataaagat gccctaaaag agttacctga agatacgaaa
     4561 aaatttgttg atcaagtgaa accacaaaat attgactggg aagctgttgg aaagcatttg
     4621 gatgaatggg tagaaaaagc tgaattagaa tacgtaaaat aagaaataag agttattttt
     4681 tatgtccaag tctctctatt atttctaaat ttaaggaaga aataaagaga ggcttttggt
     4741 tttagtaata gagggagtta gtgagatgat taaatttgat aatattcaaa ttaaatatgg
     4801 tgattttgtt gcaattgata atctgaattt agatatacat gaaggggaat tctttacatt
     4861 tcttgggcct tcaggatgtg gtaaatcaac tactttgaga gcattggtag gttttttaga
     4921 tccatcatca ggaagtattg aagttaatgg aacagatgtc actcatttgg aacctgaaaa
     4981 gcgtggaatt ggtattgtat ttcaatctta tgcgctattt ccaactatga ctgtttttga
     5041 taatattgca tttggtttaa aagttaagaa ggtagctcca gatgttatta aagctaaagt
     5101 atcagcagtg gcagcaaaaa ttaagatctc tgatcaacag ttacagcgta atgtatcaga
     5161 attatctggg ggtcaacaac aaagggtagc attggctcgt gctctggttc ttgaacctaa
     5221 aattctttgt ctagatgaac cattgtcaaa ccttgacgca aaattacgtg tagatttgag
     5281 aaaagagttg aaaagacttc aaaaagagtt aggtattact actttatatg ttactcatga
     5341 tcaagaggaa gccttgactt tatctgatag aattgcagtc tttaacaatg gatacatcga
     5401 acaggtcggt acaccagtag agatttatca taattctcaa actgaatttg tatgtgattt
     5461 cattggagat attaatgttt tgaccgatga aacagtccac gaagtattat tgaaaaatac
     5521 aagcgttttc ttagaggata aaaaaggata cattcgatta gagaaagttc gattcaatcg
     5581 tgaaactgaa caagatttta ttctaaaagg gacaattatt gatgttgagt tttctggagt
     5641 tacaattcac tatacaataa aagtttctga aagtcagatt cttaatgtaa caagtattga
     5701 tagtcaggct gctattagat ctgtcggaga aagtgtggaa ttatttatca caccatcaga
     5761 cgttctgcaa ttttaaggag gtgcagtatg cgtcataaat taaatttaaa agattggctt
     5821 attcgtttag ggttaatctg gttcttagta acatttatta tttatccaaa ctttgatcta
     5881 gtagtgaatg tatttgtaaa aggaggagaa ttttcccttg atgctgtaca tcgtgttcta
     5941 aaatctcaga gggcacttca gagtattatg aacagtttta agttagcatt ttcactcatt
     6001 attacagtta atgtcgtagg tattctttgt gttctattta cagagtactt tgatattaaa
     6061 ggtgctaaaa ttttaaaatt aggttatatg acctctttaa tttatggagg agtggtttta
     6121 gcgactggat ataaatttgt ctatggtcct tatggattga ttacaaaatt tttacaaaat
     6181 gttatccctt ctttagactc taactggttt attgggtatg gtgcagtctt attcattatg
     6241 acattttcag gaactgctaa tcatacattg tttttaacaa atacaattcg aagcgttgac
     6301 tatcacacta ttgaggctgc tcgaaatatg ggagcaaaac catttactgt tttccgaaaa
     6361 gtagtgttac caaccttaat tccaactcta tttgcactta ctattatggt ttttcttagt
     6421 ggtttatctg cagtagcagc acccatgatt gttggtggta aagaatttca aactataaat
     6481 ccaatgatta ttacatttgc agggatgggg aattctcgtg atttagctgc cttacttgca
     6541 attattttag gtattgcaac tacaattttg cttactatca tgaataagat agaaaaaggt
     6601 ggaaattata tttctatctc taagactaaa gcgcctctta aaaaacaaaa aattgcgtct
     6661 aagccttgga atatcattgc tcacattgta gcatatggat tgttcacagt tttcatgctt
     6721 ccactaattt ttatagtatt atactcattt acagatccag ttgcaattca aacaggtaac
     6781 ttaacattat caaactttac tttagaaaat tatcgcttat tctttagtaa tagtgcggca
     6841 ttctctccat tcttggtcag ctttatttat tctattattg ctgcgacaac agcaacaatt
     6901 ctcgcagttg tatttgctcg tgttgtcaga aaacataaat ctcgttttga tttcttattt
     6961 gaatatggtg ctctacttcc ttggttacta ccaagtacac ttttagcagt aagtttatta
     7021 tttactttta atcagccaca atttcttgtc ttgaatcaga ttttggtagg tagtttggta
     7081 attctactta ttgcatatat agttgtaaaa atcccatttt cttatagaat ggtacgtgct
     7141 attttattta gtgttgatga tgagatggaa gatgcagcaa gaagtatggg tgcttcacct
     7201 ttttatacta tgatgaaggt tatcattcca tttattttac cggttgttct ctctgttatt
     7261 gctttaaact ttaactcttt attaactgac ttcgacttat ctgtattcct ttaccatccc
     7321 ctagctcaac cattaggtat tacgattcga tctgcaggtg atgaaacagc aacatctaat
     7381 gcacaagctc tggtatttgt ttatacaatt gttctgatga ttatttctgg aacggtatta
     7441 tacttcacac aaagaccggg gcgtaaagta aggaaataat catgacagcc actagtcttg
     7501 ggttatcaaa tattgaaata gttgtcagga ttgttttatc agtagtcatt ggtagtataa
     7561 ttggtttaga gagagggagc aaatcccagc ctgcaggcat ccgaacttat agtattgttt
     7621 gtctagctgc atgtttgatt atgatgacga atgaatacgt atcttataaa tttgggacag
     7681 gagatcctac acgattagga gctcaagtta tatcaggtgt gggttttcta ggcgctggaa
     7741 cgattcttat tacagataaa aagaaaatta caggtctgac aactgcagca ggcatttggg
     7801 cttcggcagg aattggatta gctattggag taggttttta tgagggagct cttttagtag
     7861 ccatttctgt ttggggtgtg atatccatgt tccaaccact aaaaaaatat ctgcaaaatc
     7921 gttctaaaat gattgaattg tatatagtgg ttaaatctac agaagcctat aatcgtgtat
     7981 tggtttattg tgcagaaaat ggtatcagaa tgaccgattc aagaacagcg tttggagatg
     8041 ttaattctga cagaattgaa tactttgatg ttccggacaa aaaaatagcg tcatttatta
     8101 ctctggaatt atcaggtaga tttgaacatc ttcgactgat ggaagaaatt gctaatattg
     8161 taggtgttat ttatgtcgaa gaaattagct gaaatttagt aaacaaaggg acagatgttt
     8221 ttgtcctttt gctttttaga tgttttaatc atctaatttt tgagtagatt tttgctcaga
     8281 ggtttttatg aaagattata aaatcaattt tgatttaggt aaaatagaat attttgataa
     8341 taat
//
LOCUS       DAVKXA010000069         8308 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKXA010000069 DAVKXA010000000
VERSION     DAVKXA010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.069"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..149
                     /locus_tag="VW883_001939"
     CDS             <1..149
                     /locus_tag="VW883_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0275017.1"
                     /translation="TSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYMER
                     YRDR"
     gene            115..429
                     /locus_tag="VW883_001940"
     CDS             115..429
                     /locus_tag="VW883_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275018.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1113..1274
                     /locus_tag="VW883_001941"
     CDS             1113..1274
                     /locus_tag="VW883_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275019.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1366..3045
                     /locus_tag="VW883_001942"
     CDS             1366..3045
                     /locus_tag="VW883_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0275020.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSFKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYERVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHECTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLCR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVEHRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            3313..3879
                     /locus_tag="VW883_001943"
     CDS             3313..3879
                     /locus_tag="VW883_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275021.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4201..4389
                     /locus_tag="VW883_001944"
     CDS             4201..4389
                     /locus_tag="VW883_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0275022.1"
                     /translation="MATDKNRIMISLDDKKLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4451..5209
                     /locus_tag="VW883_001945"
     CDS             4451..5209
                     /locus_tag="VW883_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0275023.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            5267..5728
                     /locus_tag="VW883_001946"
     CDS             5267..5728
                     /locus_tag="VW883_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0275024.1"
                     /translation="MLGVIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5762..6121
                     /locus_tag="VW883_001947"
     CDS             5762..6121
                     /locus_tag="VW883_001947"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0275025.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNVISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6233..7117
                     /locus_tag="VW883_001948"
     CDS             6233..7117
                     /locus_tag="VW883_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0275026.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7280..7984
                     /locus_tag="VW883_001949"
     CDS             7280..7984
                     /locus_tag="VW883_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0275027.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDSVAWVRQGIF"
     gene            7960..>8308
                     /locus_tag="VW883_001950"
     CDS             7960..>8308
                     /locus_tag="VW883_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275028.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNIIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGY"
BASE COUNT         3011 a         1117 c         1731 g         2449 t
ORIGIN      
        1 taacttcaat tattaggcaa gctttaaaaa atactgaata taaagatcaa atatctagca
       61 cagtattgcc agatatcaaa attaaattac cgatagacag tagaggtact ccagattgga
      121 attacatgga aagatataga gatagataaa gagagagagg gagagataga taaaaagtcc
      181 acccccattt tttatggaga attcaaaaat gtaaggttaa gcaaagaaga atataaaaat
      241 ctaaaagaaa aattaaactc acacacagat ataatgataa ataaactatc cagatacatg
      301 gaaagcagtg gtaagaccta tcaaaaccac tatgtgacaa tcttaaaatg gtatgaagaa
      361 gataaagaca aactaagaca gaaaggttta aataaaaaaa tgaattatga tgtaggagaa
      421 tctttataga taaaaagagg tggaaaggca ctattaaaga ctttaagtct aaaaaggtat
      481 caaagtatgc cagagataaa aaaatataaa tataacactt taaaggcgat tagaaaatta
      541 aagaaatgct agaagacttt tagatgacag ttaccaagag ggtctaattt tcactgctac
      601 ttatgcagtg ggaatttgac ctttttatat aagcaaattc tatttcaaaa ttggttacca
      661 agaaagactt cttttcactg ttaagtataa gagggtaatt tatagaattt tgttacatta
      721 agataaatat tttctgatgg tcaaatttta aaaagattaa taactctcga taaattttga
      781 accttaacaa ttgaatagac caagacaaga cgttaattat ttttggagcg taataaccta
      841 tccgtcaaga tctttcggct gaataattcg gcaaaaaaag ttctgctaag taaaaagaaa
      901 gtgagcgata agtaagagtt tgaatatagg gagggatacc ctatccgcta tgaagaaaat
      961 gaggataatg atacttctaa ggttgaagcc ggctcatccg gaatagaggc ggaggtgaga
     1021 ttcctatgtt gctaatccaa agcacttgtc aatgtcaaaa aacttaatta aacaaataat
     1081 tattagatat aaaactttag aggaggtata tattggacaa tgactggaat ggattggctg
     1141 atttaatagc aaatctgatt gcaaaatatg ctggtgcttt agatttagat aatctacccg
     1201 atccaacgcc agcaaaaaat caagagatga aaaatagttt tgacatggca aaaacacaaa
     1261 ttgagacgga ctaataaaag tgttataata tacttgaaat gatagtccaa acttaaatta
     1321 aaaaaattat atatgatata gaaaaattat attgaggtta atactatgtc aaaagaaaaa
     1381 ataaaagtat acctctatac acgagtatct acgtcaatac agatagaggg gtattcgtta
     1441 ggggcacaaa aatcacgaat gaaagctttt gctatttaca acgattatga aattgttgga
     1501 gagtatgaag atgccgggaa gtctggcaag tctattgaag gtagaataca gttcaatcga
     1561 atgatggaag atataaaatc tggaaaagat ggagtatctt ttgttcttgt gtttaagtta
     1621 tcaagatttg caagaaatgc cgctgatgtt ctttctacac ttcagataat gcaggattat
     1681 ggagttaatc ttatctgcgt tgaagatggc attgattcat ttaaagatgc tgggaaacta
     1741 atgatttctg ttttatcagc tgtggctgaa atagaaagag aaaacatccg tattcaaaca
     1801 atggaaggtt gcattcaaaa agcaagggaa ggaaaatgga atggtggctt tgctccgtat
     1861 ggatataaac ttgaagacgg caagctgttt ataaatgagg aagaggcagt tgcaataaga
     1921 acgattttcg accagtatgt aaatactacg ataggagcca atgggatatc taaatactta
     1981 gagaatcatg gaattagaaa aatcccaaga cagaatggta agaatccttt gtttgatgca
     2041 ggtcttataa gaaagatatt aaagaatcct gtatataatg ggaaaatagc atttggaaga
     2101 agaactttag aaaaagttca tggtacaaga aatgaatata agcaggttga acaagatgaa
     2161 tatctaatat ctgaagggat acatgaagct atagtttccg atgaagtttg gcaagctgct
     2221 caggttaagc taaaatctca agcaaagaaa tatgagcgtg tgaataaagg aaaagataca
     2281 cgcacacact tgctttctgg aattgtaaaa tgcccgatat gtggagtggg aatgtttggg
     2341 aacaagtgta tcaagaaaaa gaaagatggc acaaagtata aagattttta ttactatggt
     2401 tgtaaacata ggcagatgat aagaggtcat gagtgtacat tcagtaagca aattagagaa
     2461 gaattgttag atgatgctgt tgcagaggtg attgtcaaga tagtaagtaa tccgaaattt
     2521 gcttctatga tgcaagaaaa aatcaacatg aaggtggata cctctgaaat agaaaaagaa
     2581 atagataatt accaaaagga attgagaaag agtcattcta caaagtttaa gctaattgag
     2641 gaaatagata atttagatgt tgaagataag cattataaga gaaggaaaca ggatttagat
     2701 gatagactat gtcgtatgta tgacaaaata gatgaattag aatcatcact aattgatgcg
     2761 aaagcaaaga aacagactat tgaagctgaa aagcttacag gagataacat atataaggtt
     2821 ctgatctatt ttgataagct ctataaagtc atgaatgatg tagagcatag gcagttaatt
     2881 tcagctttga tttctgaaat tcaagtttat gaagaaaaac aatctaacgg acaatggcta
     2941 aaatccatta cttttaagct accaattata gaagaaaatc tcaacatagg tttggataat
     3001 gatgaacaag ttgaatgtgt aagtttatta gagaaacgta gttaatcctc aaaaggttcc
     3061 ccaaaccttt tgagtcccac tgacgcatca cgctgaggcg gtatcactgc ttgtacgagt
     3121 tgaagcatca gcgaagtaaa agtagatgtt cagccaatgc gacgaggtga gaccgaaggt
     3181 cgataaggtg tgttctgggt ataggactcg taaagtaagt aggaaatatg atgagatgat
     3241 acagagagcc tgaattggtc aggtgacgtg cttatttaca ttagcctgat aatgaaaatg
     3301 gagagattat cgatggttat attggaattg taccaaaatg attattctaa agatttagta
     3361 gcatttgatt ccatagaaga tgggaaagcc tttgtagctc aaatcccggg atacactctg
     3421 gaaacagaag atggttttga agtggagtat tttaatccta aaaacatacc ggattatatg
     3481 gaaattattt ttaacggaaa tattgttcct ttatctaaat ttatgttcga tcctgaggaa
     3541 aatgtaaaca ttatttggaa agagatttca aatttatccc tcaaaaatga tagagtgatc
     3601 gaaggatatt caaaaattga tgcatatgtc gttaacaacc atgaagttaa agcctatgtc
     3661 gaaacaagag aaacgaacta tcgtaaagca aaagacttct tagaaagccg cggatatgaa
     3721 atcgacagaa gctttttcgg aagtgaagac ggtgaagcga ttctttacag aaaaaaaggg
     3781 atcgaagttt ggcatttctt gtgtcactta gacccaatgt ttgtagagat tgaagatgta
     3841 gaaggatatg ttaaagaaga agttggagag attcaatagt caaccaaagt tccttgtgag
     3901 tatatacctt tgctagtaaa agagtcaaaa cgttataacg aaggggggga agaaaaccct
     3961 tgagtgtaag tctttttctt gtttagaggg aaagtattag agtagccgct cataatttat
     4021 actagatttg ataactgatt tgagacagat tttatttcta taaatattgt gaaaattttt
     4081 taataccaaa gatttaaagt tactgtgtta aaaatcctct ccacttttaa actaatgtat
     4141 tataaaagcc agttgacaca agtgttacac ctgtgataga attaacttga ggtgatgaaa
     4201 atggcaaccg ataaaaatag aataatgatt agcttggatg ataaaaaact agagaaactt
     4261 gaaaatttag tagaagatgc tagagataga aggggaatgc gactaacaaa gtcccaggtt
     4321 attgaattac tcctaaatac cgttgattat ttcgatgata ttatgggagc tatttactca
     4381 aaaaaataag agcaaaattg ctattatttt ttacaaatcg gtgtaacact agtgatatag
     4441 gagtgatgaa atggttgttt atattagaca aagtaaatta ccaagtgagg tttcaattaa
     4501 taaatacaat gctcaagtag gtgcctactt acaaggagaa gaagttattt tatatcaatc
     4561 tttttctgaa ataaaagagt taacaagtga agatatagtt gtagattata taatggagac
     4621 tagagcatta ctaaaaatga tgggcttaaa cgttccggtt tatgactatc ctattgagct
     4681 taaagagttt tatggtcgaa agatttatgc tggtatttta ggagagattg tgaatatacc
     4741 tgataattgg ggaaaattta ttaagcctaa agctggttca aaagtcttta ctggaagagt
     4801 tgttaatgga acccatgatt taataggtat tggtctacct ttcgactatc ctatatggat
     4861 tagtgaggtt gtagaattca tagctgaatg gcgttgtttt gtgttagatg gtcgcgtatt
     4921 agatgttcga ccctatacag gtgattatca tgcacaattt gatgcaagtg taattgatga
     4981 agcgatatca tgttggaaag atgcgccaat agcttatgga ctagatatcg gtgttactcg
     5041 cgatggcaga acacttgttg ttgaagtaaa tgatggttat gcattgggaa attatggcct
     5101 atctccttta aaatcaatca attttcatag agctaggtgg aaagaaatgg taaaacccta
     5161 ttttgaaaaa aatgaaattt ttaaaattca acaggatgtt attttctaaa ataaatatgg
     5221 tagataacca atataaaaag catcaaaatg aacaaggagg aatctgatgc ttggagtaat
     5281 tattggagat attgtcggtt ctgtttacga atggaacaat atcaaaacaa aggactttcc
     5341 tttatttcgg aaggactgct tttttacaga tgacacggtt atgacctgtg ctgttgcaga
     5401 agcaattatg aatggtggac aaaaagacga cttcattgac gcgatgaaga aatatggcag
     5461 aatgtatccg aatgctgatt acggtgctcg gtttaatgca tggctaaaca gcgataaccg
     5521 tgagccttat aatagctttg ggaatggatc agctatgcgt atttctccat gtgcttggat
     5581 catggactgt ggtttttatg cgaaaactgg tatatggcca tcatctagag gacttacgag
     5641 tctttctgca gaggtaactc ataatcatcc agaaggtgtc aaaggcgcta tggctacagc
     5701 tgatgctatc tttctatgtc gtttttaatt tggtggttat tgtagagagt acgagtaatc
     5761 aattaacgac aatcctatag agtgtaaaag acgaattaag gattatatag aaaaagaata
     5821 cgattacaat ctatctcaaa ctttagatga aatccgtcct aactatcgtt ttaacgaaac
     5881 atgtcaggaa actgtccctc aagccattat cgcctttctt gaaagtagag acttcgaaga
     5941 tgcgataaga aatgtcatct cacttggtgg cgacagtgat actctcgcag caatcacttg
     6001 tagcatagca gaggcagctt acggtattcc tgattggatc aaggataagg cctattctta
     6061 cttggatgaa cccttaaagg atgtagttag gcgatgggaa aatagaataa aagtgtatta
     6121 atctccagta cgtcagattt ctcttttctg tattttcatt gtataatagg attacattta
     6181 cttgcatacg acgaaatgta aacatttctg tttaaaatta aggataaaat caatgaaaaa
     6241 agcaatggta attatcaacc ctacttctgg tggcgagaag gctttggatt acaaagaaaa
     6301 gctggagaat aaagcaaaag aatactttga atatgttgaa accaaaatta ccgaaaaagc
     6361 gctggatgca acacattttg ctgaagaagc ttctcgtgag cagtatgatg cagtggttgt
     6421 gtttggtgga gatggaactg tcaatgaagt catttcaggt attgatgaga gagactacat
     6481 tcctaagtta gggattatcc caggcggtac aggtaacctc attacaaaac ttttggaaat
     6541 caatcaagac atcgatggcg caattgacga actggatttt gatttaacca ataagattga
     6601 tatcggtaaa gcaaatgaca actattttgg ttatatcttt agtatcggtt ctctgcctga
     6661 ggcgattcac aatgttgaaa tagaggacaa aacaaaattc ggtattttaa cctatgctgt
     6721 aaataccatg aagtctgtca tgacagatca ggtctttaac attaaggttg agacagaaaa
     6781 tggaaattat gttggtgaag ctagccatgt tttggtcctt ttgacaaatt acttcgctga
     6841 taagaaaatc tttgaagaaa acaaggacgg ctatgccaac attttgattc tgaaagatgc
     6901 ctctatattc tccaaattat ccgtcattcc tgatttatta aaaggggatg ttgtcgcaaa
     6961 tgataatatc gagtatatca aagcgcgtaa tattaaaatc tcttcagata gtgaattgga
     7021 gtcagatgtt gacggagata aatcagataa cctacctgta gaaatcaaag tcctagctca
     7081 gcgagtagaa gtattttcaa aaccgaaaga ggattagtat atagagaaag ccttttttaa
     7141 ggctttttgt atactttaaa agatagttcc tttaacaacg gacattcctt gcaaatagtt
     7201 tacaaaaata gtatactgga tttattgagt ttgaaaacgt ttgcgtaaaa tttgaatgaa
     7261 tactttagga gacaaattga tggaattgag tgctatttac cataggcctg agtcggagta
     7321 tgcctatctt tataaggata agaaactcca tattcgaatt cgaactaaga aaggggacat
     7381 tgaaagcatc aacttgcact atggggaccc ttttatcttt atggaggagt tttatcagga
     7441 tacaaaagaa atggtcaaga taacttctgg taccttattt gaccattggc aggttgaagt
     7501 gtcagttgac tttgcacgta tccagtatct ctttgagctc agagatacag aaggtcaaaa
     7561 tattttgtat ggcgataaag ggtgtgtgga aaattctcta gaaaatcttc atgcaattgg
     7621 gaatggattt aagttgcctt atcttcatga gattgatgcc tgcaaggttc ctgactgggt
     7681 ttcaaatacg gtatggtatc agatatttcc tgaaagattt gccaatggca atgctctatt
     7741 aaacccagaa gggactttag actgggattc atctgtcaca cctaagagcg atgatttctt
     7801 tggtggtgat ttacagggga ttattgatca tatggattac ttgcaagact tgggtattac
     7861 tggactatat ctttgtccca tctttgaatc tacaagcaat cacaagtaca atacgacaga
     7921 ttactttgaa attgaccgtc attttggaga cagtgttgca tgggtgcggc aagggatttt
     7981 ttagaactaa ttaatcacaa agggctacct ctttttaatc cgcttgtagg tgattctcat
     8041 gtaaataata gacaagaata tgacaataca gggagtggaa atttacaacc tgaaaagtgg
     8101 aatgaaactg caaagcagct ttataatatt ataatgtggt tgattatttt atggaatgct
     8161 aagccggata cacctttatt taattttaaa gacgaagtaa ttaagtataa aacatatgag
     8221 ccttttgaaa gcagtataaa aagagtaaat actactataa agaatggtag taaagggaaa
     8281 actctgactg agatgattaa tggctaca
//
LOCUS       DAVKXA010000070         8035 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKXA010000070 DAVKXA010000000
VERSION     DAVKXA010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.070"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            191..2173
                     /locus_tag="VW883_001951"
     CDS             191..2173
                     /locus_tag="VW883_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0275029.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2473..7776
                     /locus_tag="VW883_001952"
     CDS             2473..7776
                     /locus_tag="VW883_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0275030.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENHSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTAESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKSDAPTVEKPEFKLSSLASEQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
BASE COUNT         2641 a         1521 c         1754 g         2119 t
ORIGIN      
        1 attaggaact atccgtgagt tctctagtct ggagattttt caatatactt cgttattggg
       61 cgcttacaat gatattcata ttttttgcaa agatgttgtt tgaaaaataa ttttcaaaaa
      121 ttctgaaaat tctgttgaca actttctgaa aagagtctat aatggagaga aagttttaaa
      181 ggagaaaatg atgaaaagtt caaaactatt tgcccttgcg ggcgtgacat tattggcggc
      241 gactacttta gctgcatgct ctggatcagg ttcaagtact aaaggtgaga agacattctc
      301 atacatttat gagacagacc ctgataacct caactatttg acaactgcta aggctgcgac
      361 agcaaatatt accagtaacg tggttgatgg tttgctagaa aatgatcgct acgggaactt
      421 tgtgccgtct atggctgagg attggtctgt atccaaggat ggattgactt acacttatac
      481 tatccgtaag gatgcaaaat ggtatacttc tgaaggtgaa gaatacgcgg cagtcaaagc
      541 tcaagacttt gtaacaggac taaaatatgc tgctgataaa aaatcagatg ctctttacct
      601 tgttcaagaa tcaatcaaag ggttggatgc ctatgtaaaa ggggaaatca aagatttctc
      661 acaagtagga attaaggctc tggatgaaca gacagttcag tacactttga acaaaccaga
      721 aagcttctgg aattctaaga caaccatggg tgtgcttgcg ccagttaatg aagagttttt
      781 gaattcaaaa ggggatgatt ttgccaaagc tacggatcca agtagtctct tgtataacgg
      841 tccttatttg ttgaaatcca ttgtgaccaa atcttctgtt gaatttgcga aaaatccgaa
      901 ctactgggat aaggacaatg tgcatattga caaagttaaa ttgtcattct gggatggtca
      961 agataccagc aaacctgcag aaaactttaa agatggtagc cttacagcag ctcgtctcta
     1021 tccaacaagt gcaagtttcg cagagcttga gaagagtatg aaggacaata ttgtctatac
     1081 tcaacaagac tctattacgt atctagttgg tacaaatatt gaccgtcagt cctataaata
     1141 cacatctaag accagcgacg aacaaaaggc atcgactaaa aaggctctct taaacaagga
     1201 tttccgtcag gctattgcct ttggttttga tcgtacagcc tatgcctctc agttgaatgg
     1261 acaaactgga gcaagcaaaa tcttacgtaa tatctttgtt ccaccaacat ttgttcaagc
     1321 agatggtaaa aactttggcg atatggtcaa agagaaattg gtcacttatg gggatgaatg
     1381 gaaggatgtt aatcttgcag attctcagga tggtctttac aatccagaaa aagccaaggc
     1441 tgaatttgct aaagctaaat cagccttaca agcagaaggt gtgactttcc caattcattt
     1501 ggatatgcca gttgaccaga cagcaactac aaaagttcag cgcgtccaat ctatgaaaca
     1561 atccttggaa gcaactttag gagcggataa tgtagtcatt gatattcaac aactacaaaa
     1621 agacgaagta aacaatatta catattttgc tgaaaatgct gctggcgaag actgggattt
     1681 atcagataat gtcggttggg gtccagactt tgccgatcca tcaacctacc ttgatatcat
     1741 caaaccatct gtaggagaaa gtactaaaac atatttaggg tttgactcag gggaagataa
     1801 tgtagctgct aaaaaagtag gtctatatga ctacgaaaaa ttggttactg aggctggtga
     1861 tgagactaca gatgttgcta aacgctatga taaatacgct gcagcccaag cttggttgac
     1921 agatagtgct ttgattattc caactacatc tcgtacaggg cgtccaatct tgtctaagat
     1981 ggtaccattt acaataccat ttgcattgtc aggaaataaa ggtacaagtg aaccagtctt
     2041 gtataaatac ttggaacttc aagacaaggc agtcactgta gatgaatacc aaaaagctca
     2101 ggaaaaatgg atgaaagaaa aagaagagtc taataaaaag gctcaagaag atctcgcaaa
     2161 acatgtgaaa taactgttgc aaaatataag aaaggattta gtatttctct tgaatgctga
     2221 atcctttttt atatttgtaa agaaagattc taaatgtact gacccccaaa agttggagcc
     2281 tctttttgtc agaatagaga aaatttttgt taattttact tgtttcctat tgctttctca
     2341 gttattattt gttatattaa aagtataatt atttttattt atcagggtta agcattgcac
     2401 tttcagagga aggagtattt tttaaaaaga aaatgtaaac gcttgctaaa aaatgaaagg
     2461 atttagaagt ttatgaataa aggattattt gaaaaacgtt gtaaatatag tattcggaaa
     2521 ttttcattag gtgttgcttc tgttatgatt ggagctgcat tctttgggac aagtccggtt
     2581 cttgcagata gcgtgcagtc tggttccacg gcgaacttac cagctgattt agctactgct
     2641 cttgcaacag caaaagagaa tgatgggcgt gattttgaag cgcctaaggt gggagaagac
     2701 caaggttctc cagaagttac agatggacct aagacagaag aagaactatt agcacttgaa
     2761 aaagaaaaac cggctgaaga aaaaccaaaa gaggataaac ctgcagctgc taaacctgaa
     2821 acgcctaaga cggtaacccc tgaatggcaa acggtagaga aaaaagaaca acagggaaca
     2881 gtcactatcc gagaagaaaa aggtgtccgc tacaaccaac tatcctcaac tgctcaaaat
     2941 gataacgcag gtaaaccagc cctgtttgaa aagaagggct tgaccgttga tgccaatgga
     3001 aatgcaactg ttgatttaac cttcaaagaa gattctgaaa agggcaaatc acgctttggt
     3061 gtcttcttga aatttaaaga taccaataat aatgtttttg tcggttatga caaggatggc
     3121 tggttctggg agtataaatc tccaacaact agcacttggt atagaggtag tcgtgttgct
     3181 gctcctgaaa caggatcaat aaaccgtctc tctatcactc tcaagtcaga cggtcagcta
     3241 aatgccagca ataacgatgt caatctcttt gacacagtga ctctaccagc tgcggtcaat
     3301 gaccatctta aaaatgagaa gaagatcctt ctcaaggcag gaacttatgg caatgaccgt
     3361 acggttgtca gcgttaaaac ggataaccaa gagggggtaa aaacagagga tacccctgct
     3421 gaaaaagaaa caggtcctga agttgatgat agcaaggtga cttatgacac gattcagtct
     3481 aaggtcctca aagcagtgat tgaccaagcc ttccctcgtg tcaaggaata cagcttgaac
     3541 gggcatactt tgccaggaca ggtgcaacag ttcaaccaag tctttatcaa taaccaccga
     3601 atcacccctg aagtcactta taagaaaatc aatgagacaa cagcagagta cttgatgaag
     3661 cttcgcgatg atgctcactt aatcaatgcg gaaatgacag tacgcctgca agttgtggac
     3721 aatcaattgc actttgatgt gaccaagatt gtcaaccaca atcaagtcac tccaggtcaa
     3781 aagattgatg acgaaagaaa actactttct tctattagtt tcctcggcaa tgctttagtc
     3841 tctgtttcta gtgatcaaac tggtgctaag tttgatgggg caaccatgtc aaacaatacg
     3901 catgtcagcg gagatgatca tatcgatgta accaatccaa tgaaagacct agccaagggt
     3961 tacatgtatg gatttgtttc tacagataag cttgctgctg gtgtttggag taactctcaa
     4021 aacagctatg gtggtggttc gaatgactgg actcgtttga cagcttataa agaaacagtc
     4081 ggaaatgcca actatgtagg aatccacagc tctgaatggc aatgggaaaa agcttataaa
     4141 ggcattgttt tcccagaata cacgaaggaa cttccaagtg ctaaggttgt tatcactgaa
     4201 gatgccaatg cagacaagaa cgttgattgg caagatggtg ccattgctta tcgtagcatt
     4261 atgaacaatc ctcaaggttg ggaaaaagtt aaggatatca cagcttaccg tatcgcgatg
     4321 aactttggtt ctcaagcaca aaacccattc cttatgacct tggatggtat caagaaaatc
     4381 aatctccata cagatggtct tgggcaaggt gttctcctta aaggatatgg tagcgaaggc
     4441 catgactctg gtcacttgaa ctatgctgat attggtaagc gtatcggtgg tgtcgaagac
     4501 ttcaagaccc taattgagaa ggctaagaaa tatggagctc atctaggtat ccacgttaac
     4561 gcttcagaaa cttatcctga gtctaaatac ttcaatgaaa aaattctccg taagaatcca
     4621 gatggaagct atagctatgg ttggaactgg ctagatcaag gtatcaacat tgatgctgcc
     4681 tatgacctag ctcatggtcg tttggcacgt tgggaagatt tgaagaaaaa acttggtgac
     4741 ggtctcgact ttatctatgt ggacgtttgg ggtaatggtc aatcaggtga taacggtgcc
     4801 tgggctaccc acgttcttgc taaagaaatt aacaaacaag gctggcgctt tgcgatcgag
     4861 tggggccatg gtggtgagta cgactctacc ttccatcact gggcagctga cttgacctac
     4921 ggtggctaca ccaataaagg tatcaacagt gccatcaccc gctttatccg taaccaccaa
     4981 aaagatgctt gggttgggga ctacagaagt tatggtggtg cagccaacta tccactgcta
     5041 ggtggctaca gcatgaaaga ctttgaaggc tggcaaggaa gaagtgacta caatggctat
     5101 gtaaccaact tatttgccca tgacgtcatg accaagtatt tccaacactt cactgtaagc
     5161 aaatgggaaa atggtacacc ggtgactatg accgataacg gtagcaccta taaatggact
     5221 ccagaaatgc gagtggaatt ggtagatgct gacaataata aagtagttgt aactcgtaag
     5281 tcaaatgatg tcaatagccc acaatatcgc gaacgtacag taacgctcaa cggacgtgtc
     5341 atccaagatg gttcagctta cttgactcct tggaactggg atgcaaatgg taagaaactt
     5401 tctactgata aggaaaaaat gtactacttc aatacgcagg ctggtgcaac aacttggacc
     5461 cttccaagcg attgggcaaa gagcaaggtt tacctttaca agctaactga ccaaggtaag
     5521 acagaagagc aagaactaac tgtaaaagat ggtaaaatta ccctagatct tctagcaaat
     5581 caaccatacg tactttaccg ttcaaaacaa accaatcctg aaatgtcatg gagtgaaggc
     5641 atgcacatct atgaccaagg atttaatagt ggaaccttga aacactggac catttcaggc
     5701 gatgcttcta aggcagaaat tgtcaagtct caaggggcaa acgatatgct tcgtattcaa
     5761 ggaaacaaag aaaaagttag tctcactcag aaattaactg gcttgaaacc aaataccaag
     5821 tatgccgttt atgtcggtgt cgataaccgt agtaatgcca aggcgagcat cactgtaaat
     5881 actggtgaaa aagaagtgac tacttatacc aataagtctc tcgcgctcaa ctatgttaag
     5941 gcttacgccc acaatacacg tcgtgacaat gctacagtta acgatacaag ttacttccaa
     6001 aacatgtacg ccttctttac aacaggatcg gacgtctcaa atgttactct gacattgagt
     6061 cgtgaagctg gtgatcaagc aacttacttt gatgaaattc gtacctttga aaaccattca
     6121 agcatgtatg gagacaagca tgatacaggt aaaggcacct tcaagcaaga ctttgaaaat
     6181 gttgctcagg gtatcttccc atttgtagtg ggtggtgttg aaggtgttga agataaccgc
     6241 actcacttgt ctgaaaaaca tgatccatat acacaacgtg gttggaacgg taagaaagtt
     6301 gatgatgtta tcgaaggaaa ttggtcactc aagacaaatg gactagtgag ccgtcgtaac
     6361 ttggtttacc aaactattcc gcaaaacttc cgttttgaag caggtaagac ctaccgtgta
     6421 acctttgaat acgaagcagg ttcagacaat acctatgctt ttgtagtcgg taagggagaa
     6481 ttccagtcag gtcgtcgtgg tactcaagca agcaacttgg aaatgcatga attgccaaat
     6541 acttggacag attctaagaa agccaagaag gcaaccttcc tcgtgacagg tgcagaaaca
     6601 ggggatactt gggtaggtat ctactcaact ggcaatgcaa gtaatactcg tggtgattct
     6661 ggtggaaatg ccaacttccg tggttataac gacttcatga tggataatct tcaaatcgaa
     6721 gaaattaccc taacaggtaa gatgttgaca gaaaatgctc tgaagaacta cttgccaacg
     6781 gttgccatga ctaactacac caaagagtct atggatgctt tgaaagaggc ggtctttaac
     6841 ctcagtcagg ccgatgatga tatcagtgtg gaagaagcgc gtgcagagat tgctaagatt
     6901 gaagccttga agaatgcttt ggttcagaag aaaacggctt tggtagcaga tgactttgca
     6961 agtcttacag ctcctgctca ggctcaagaa ggtcttgcaa atgcctttga tggaaactta
     7021 tctagtttat ggcatacatc atggggcgga ggagatgtag gcaagcctgc aaccatggtc
     7081 ttgaaagaag caactgaaat cactggactt cgttatgttc cacgtggatc aggttcaaat
     7141 ggtaacttgc gtgatgtgaa acttgttgtg acagctgagt ctggcaagga gcataccttt
     7201 actgcaactg attggccaga taacaataag ccaaaagaca ttgattttgg taagacaatt
     7261 aaggctaaga aaattgtcct tacaggtact aagacttacg gagatggtgg cgataaatac
     7321 caatctgcag cggaacttat ctttactcgt ccacaggtag cagaaacacc tcttgacttg
     7381 tcaggctatg aagcagcttt ggctaaggct cagaaattaa cagacaaaga caatcaagag
     7441 gaagtagcta gcgttcaggc aagcatgaaa tatgcgacgg ataaccatct cttgacggaa
     7501 agaatggtgg aatactttgc agattatctc aaccaattaa aagattctgc tacgaaatca
     7561 gatgctccaa ctgtagagaa acctgagttt aaacttagct ctttagcttc cgaacaaggt
     7621 aagacgccag attataagca agaaatagat agaccagaaa cacctgaaca aatcttgcca
     7681 gcaacaggtg agagtcaatc tgacacagcc ctcttcctag caggtgttag cctagcccta
     7741 tctgctctct ttgtagtaaa aacgaagaaa gactagtatt tagtaaaacc tcttaacaag
     7801 attacggaag cagtctctat cttttccaat gaggtttata gtacagaaaa agcctgagaa
     7861 gatgtcttct caggcttttg ttaagcacat aaatacaata gtgctatgaa aaaatcaccc
     7921 agaaaaatct ggctctataa tatctatagt gggtaaatcc actatagata ttatggagcc
     7981 tattttattg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca aaacc
//
LOCUS       DAVKXA010000071         7153 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKXA010000071 DAVKXA010000000
VERSION     DAVKXA010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.071"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(359..1252)
                     /locus_tag="VW883_001953"
     CDS             complement(359..1252)
                     /locus_tag="VW883_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0275031.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(2006..2236)
                     /gene="blpU"
                     /locus_tag="VW883_001954"
     CDS             complement(2006..2236)
                     /gene="blpU"
                     /locus_tag="VW883_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0275032.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGVARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(2439..2729)
                     /locus_tag="VW883_001955"
                     /pseudo
     CDS             complement(2439..2729)
                     /locus_tag="VW883_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(2775..3008)
                     /locus_tag="VW883_001956"
     CDS             complement(2775..3008)
                     /locus_tag="VW883_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0275033.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(3014..4006)
                     /gene="plsX"
                     /locus_tag="VW883_001957"
     CDS             complement(3014..4006)
                     /gene="plsX"
                     /locus_tag="VW883_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0275034.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(4003..4773)
                     /gene="recO"
                     /locus_tag="VW883_001958"
     CDS             complement(4003..4773)
                     /gene="recO"
                     /locus_tag="VW883_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0275035.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(4770..5939)
                     /locus_tag="VW883_001959"
     CDS             complement(4770..5939)
                     /locus_tag="VW883_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0275036.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAGKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6088..7098
                     /locus_tag="VW883_001960"
     CDS             6088..7098
                     /locus_tag="VW883_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0275037.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVVGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT         2038 a         1705 c         1164 g         2246 t
ORIGIN      
        1 cactaagact caataaaaga taatgtctat ttaactttta tacgattact accttctttt
       61 tagtttacac ttcctacatc ataaataaac atactcaacc ctcacaatct ccaaataact
      121 cttctatatc attgaaaatt gagtttcatc ctctatacta atgtaggaca ttcctttaat
      181 ccaatataag aataccttgt tccattaatc tctacccgat attatagata gaaccaaatt
      241 cctatactta aaaggacaaa taacgttcca accataataa acctcctttc tttttgagaa
      301 cgttttcttt ataggtttag tatagcaaaa acatgaaaaa aacaacatga cttagaagtc
      361 aggttgttgg gaaatctatc tgtttttctg ctaaaattct ctgaactaat acctgatcgt
      421 ctagcaattc tgctagagaa atcgcctttt catagaaact ttctgcctct aaaatattct
      481 tgtctacaaa taaagcatat tttgccttta gcaaaaatag atgaggtcgg taaaaaacat
      541 gtcttgtttt agcaataatt ttctcaaatg tttgaatata tatcagacta tcttctgtct
      601 gaatttggat aaataggctc agaagaactt tttccatttg aactaggcta gccttatctt
      661 catattctga acatagcaat actttttgag ctaactcctc aaaatgttct ttatcttcta
      721 atcccatagc acaacaaaag aaatacaatt caataatcaa caaatcattt acagaaaaat
      781 atttcttttt taataactgc tggaaatatt cttccactaa ccctaaaccg taggtcacat
      841 ctgaactacc ataaatatca aaacgagctt gtgtcacatc cacaattaac tgctcttcct
      901 caggcaaatt ctcataatag ttttcatata tttcctcaag tatagcttct tttcgttcga
      961 ttcttccctt atcagcgtag gtttgagaat gaatcagctc atctttgagt tttaggaatc
     1021 cttttggaat ctctataacc ttaacatcca caatattctg taatgatact ccaagtttat
     1081 ccgcaatcaa taataattta ggaagtgttg ctaaagcttg cccattttca atacgtgcta
     1141 gctgacgaat cgtcaactct gattcatcac cacaaatatc tatctgagtt tttccacaag
     1201 atcgcctaat agttttgatt ttataaccaa tttcacgttt caactcatcc atagtaatac
     1261 tccttaagtt gattacaaag atttcttttt cttcctaatt cttttgtcaa tcatatataa
     1321 aacgataagc gaaaacagcg gtagaacaat ataactcttt tcactcatta tcagctgaaa
     1381 tcccagggtt gctagtatct taaagatgaa aatattcatc aaaaatagaa aaacaaatac
     1441 taaaaaatat tttaaaacct tcttcatttc ttttcttcaa ctttcctaat ttctacacct
     1501 attttatcga aaatatatat aaaactccaa ataaacactt cgactgcact ttttttggca
     1561 aaaaatagac agaacaaaca tcctacctac taaaaatatg atatgaaagg aaaatgattt
     1621 tttactgaca ccctaggcaa gcttgggaca aataaatcat tgatagcaac atttacgaca
     1681 tcctatttaa agttccttca atttctaatg tccccgctat ttctaagcca cctctggtat
     1741 gatctattcc tagtcagaat agataacacc gttctaaatc acgattcata gttactcctt
     1801 ttttgactcg ttactataag actcctcttt acatgcgcaa aataattttg attcagattc
     1861 atcatttata gttttgatta ttttttaaca gatttttctg ttttcttctc cgaagacttt
     1921 aaaaattttt ttctaattaa atcatccata taaggaccaa atataccaac tactaaacca
     1981 ataataaaac ttttaaaatc cataattacc accaacatgt cgctgcatag gccacacctc
     2041 caagtatagc tcctcccgca gcaccagttg ctgcaccttg ccatgttctt gttttaattc
     2101 ctagctgaag acctcgtgct actcctcctc caacacctgc tttggcaaaa tctccccaat
     2161 tgcatccgcc accttcaacg caagcaagca tctcagtatc cataatttca aattgtgaca
     2221 tcttttttgt attcataacg aatacctctt ttttattttt aatatttgtc ttgttacaaa
     2281 cttgacaagt ttagtataac agtatctatt aatttttttc atccaaatct tgaattggca
     2341 tcgaaacgtc ttgaattagc ttttttgttt caaaatcatc tctattttta aaaaagatgt
     2401 tttctaatca cttttttact attagacttc ctgcaaaact agaatcctag ttcatgattg
     2461 ataataccag caatcaaatt cattcgtaat ccgaagcgtt tacgatgatt tcgataggtt
     2521 gttgaaaaca ttttaaacgt ttttactttg gcaaagatat tctcaacctt gcttctctcc
     2581 ttagatagcg catggttaca ggctttatct tcaactgtta gcggcttgag tttgctggat
     2641 ttacgtggag tttgtgcttg aggatatatc ttcatgagcc cttgataacc actgtcagcc
     2701 aagattttac cagcttgtcc gatatttctc atttctaaaa accatctact tccgttgact
     2761 tggaactccg attgctattt tccttgaatg attttaacca catctcctac actttggagt
     2821 tggtcaattt cctcatcgct gatttcgata ctaaattcat cttccagagt caagataaac
     2881 tccatcaagt caacagaatc cgcatccaaa tcgtctttca gactcaagga ttctgtcacg
     2941 acaaagtcct ctccctgtcg ctcttggata atggtcacaa tacggtcaaa aatttctttt
     3001 tctgtcatct cttttattct cctgaaaatt cacgcgcagt ctgggcaacc acgtctgttt
     3061 ctagcatggt acgaatctga cgaatcgtac tataaacagc cttggcatcg cttgagccat
     3121 gagtcttgac aacaggtgcc ttaacaccaa acaagaccgc tccaccaaca tctgaataat
     3181 tgagctgttt tttcaaacca ctgaggctgt ccttgagaag gagggcacct agtttcgctc
     3241 gaagaccacc acctgtaata gctgtcttga gcaagcccac gattcccata gctgtccctt
     3301 cgatggattt gagcacagcg tttcccgtga aaccatctgc cacaacaaca tctgcaacgc
     3361 cattcatcaa atcacgcgct tccacgtttc cgataaagtt caaactttca tcagccgcca
     3421 gtaattcata agtttcctta cgaagcgggt cgcccttgct actctctgtt ccgttgttga
     3481 gcaaaccaac gcgtggttgc gcaatgccac ggacattttt agcatagaag gaacctagaa
     3541 ccgcatattg atggaggtgc tgggctgtat tttctgcatt ggcaccaagg tctagcatgt
     3601 caaaaccttt tccatcaacg gtaggcaagg tagacatgag tccaggacgg tcgatattct
     3661 tgatacgacc cacgatgaag aatcctgctg ccaacaaggc acctgtattc ccagccgaaa
     3721 ggacagcgtc tgcttcacca tctttgacag ccttggctgc caataccata ctggcatttt
     3781 tcttattcct aatagctctc gtaggttcat catccgaatc aatcttctca tccgtatgga
     3841 taatgctgac gcgctctgtc gctgtcagat attgcttgat tttagcttca tctccgtaaa
     3901 gttgaacctc gatatctgaa aagtcagata gggcttgatt gacaccctca acaatggcct
     3961 gaggtgcgta atcgcccccc atggcatcta ctgcgatttt tttcatttct tttcctcttt
     4021 tagtaattgt ccccagtctg ctagggaatc aataaatttc tttgatttta ggtgaatccc
     4081 aacgtactct tcatataatt gatccataaa ttggcgtagc tcttgcttga ttccaggctt
     4141 gagcgaaatg gtctccaaag tctcaaaatc aatagcttga aattgattga gcagataggg
     4201 gatattggga ttgagatgac aacgtctctt atcctcatga taatgctctg gacagaggca
     4261 ggctccatat ttgaaagaaa agtcaaaagc ctgaccaacc cgatggcaga agacacactc
     4321 attaaaattg aggctgattc caaatcgagt caaaatttga atttcaaaaa tattggtcaa
     4381 aacctgataa tccaagcctg cttccatcaa ctccaaagtc ttttgcaaaa aagcaaacaa
     4441 gggagcatcc tgctgattgt cctgcaaact agcatctgca agagctgcca cataggtcgc
     4501 ataggccatg acaaagaggt cactattaat cttgggaaaa gtcatgacct catgatagtc
     4561 ttcgatgtaa ctgagtccgt catcattgat tcgcaagaga aatcgtgcca gcaccaaggg
     4621 ctgaataaca ggcgccagct tagactgacc agcgtgtttg acaaaaaaca tgcgtttgcc
     4681 aacctgctct gtaaaaattt tgacgagctt gtcatcctca cgaaaattgc gattgtaaag
     4741 caccaagcct tgactcgtga tagactgaat catgcttctc tcatgtactc ctcaagtcgt
     4801 ttcatggctt ctttgatagt ctccatgctg gctgcataag ataggcggac gtagccttcc
     4861 ccgtaacgtc caaaggctgc accagggata aaggcaacgg ccttcttctg agcaaaatcc
     4921 ttcagaaaag caaaggagtc ttgattgtag cccgctggaa ttttagcaaa aatatagaag
     4981 gcaccgtctg gtttgataat ctcaaaacca agagcagtca ttttttcgat gatatagtcc
     5041 cgacgttgga tatattcctt cttcatgggc tccgcatcgt ttttaccagc cgtcaaggct
     5101 tctaccgcag catgttgcgc catggtattt gcggcagtga ccaagtactg gtgactcttg
     5161 attaactggg ctgtgaaggc cgcaggagcg aaaatcagcc ccaaacgcca acctgtcatg
     5221 gcatgcgatt tagacaaacc attgataata atagcctggt ctctcaacat cgttcctaga
     5281 gacacatggg cttcgcctgt gtaggtcaat tctgagtaaa cctcatcaca gacaacaaaa
     5341 atttcgtact tgcgtaaaac agctgccaag gcctctaact gctctcgact gtaggtaatt
     5401 cctgtcggat tggctggata gttgagaata accgccttga gcttatcacc ctgctccaaa
     5461 atggccttct ccaacatctc aggagtcaag acaaaaccat tttcagtcgt atcaatctca
     5521 acaatttctg ccccaactaa gttaacaatc ggttcatagc ctggataagc aggagctggc
     5581 aaaagtacct tgtctccctc ttccaaaata gccgtcaaag tcgcagataa agcctctgtc
     5641 gccccaattg taaccaagat ttcattttca ggagcatagt ccagttggta cttttcctta
     5701 acaaagtcac tggctgcctg acgtagagtc agcagaccac tcatccctgt atagtaggat
     5761 tggttctgat caatcgctcg cttgcccgcc tccttgacat ggtctggcgt tgtaaaatca
     5821 ggttccccca aggtcaaacg caagacccca ggaatctccg aaatagcctg gtcaaactga
     5881 cgaatcaacg aaacttgaat tttatctaac tgtttattaa agcgcttagt taagtccata
     5941 gatacctcct actttcaaaa cgtatctcta ttatactaca aaagcccccc gaccgcaaaa
     6001 atacattaga gaatagcttt ccactttcta ttttactttt cctgtttata ggtctataat
     6061 ggtaatagat tttatttgga ggtttttatg tcatttctat caaaaaatgg agcaggtatc
     6121 ttggcctgcc ttctcatttc catcctatct tggtacttag gaggattctt ccctgtggtt
     6181 ggcgcgcccg tttttgcgat ttttatgggc atgctcctac atccctttct ctcgtcctat
     6241 aaacaactgg atgctggttt gacctttagt tccaagaagt tgctccaata tgccgttgtc
     6301 ttgcttggtt ttggtctcaa tatctcgcag gtcttcgcag ttggccaatc ttcactccct
     6361 gtcatcctgt ccactatctc aatagctctg attattgcct acctcttcca gcgtttcttt
     6421 gcactggata caaaactggc taccttggtt ggagtaggtt cttctatctg tgggggttct
     6481 gccattgcag cgacagcgcc tgttatccat gctaaggaaa aggaagtagc ccaagccatt
     6541 tccgttatct ttttcttcaa tgtcttggct gcgctcatct ttccaaccct cggcacctgg
     6601 cttcatctat ccaatgaagg cttcgccctc tttgcaggga ctgcggtcaa cgacacttcc
     6661 tctgtaacgg ctgccgccag cgcttgggac agtctttacc aaagcaatac cctcgagtct
     6721 gcaaccattg ttaaactcac acgtactttg gccattatcc ctatcacgct ctttctatcc
     6781 tactggcaaa gtcgccaaca agaaaacaag caaagcctac aactgaaaaa agtcttccca
     6841 ctttttatcc tttactttat ccttgcctct ctcctcacta cactactcac ctctctaggt
     6901 gtgtccagta gtttctttac ccctctcaaa gaactctcta aattccttat tgtcatggcc
     6961 atgagtgcta tcggtctcaa aaccaatctg gtcgctatgg tcaaatccag tggaaaatcc
     7021 attcttcttg gagccatctg ctggattgcc atcatcctca ccactcttgg tatgcagacc
     7081 cttatcggca ttttctaata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
     7141 ccgtatatat gtt
//
LOCUS       DAVKXA010000072         6761 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKXA010000072 DAVKXA010000000
VERSION     DAVKXA010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.072"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..296)
                     /locus_tag="VW883_001961"
     CDS             complement(<1..296)
                     /locus_tag="VW883_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0275038.1"
                     /translation="MNRLKELRQEKKLSQKEIAETLGFSLRSFQRMENGESQIKPEKA
                     QLLADYFGVSVANLLGYENNFIESVKNLSQKDGSDEVFFKAFRAYYELKTADGR"
     gene            515..715
                     /locus_tag="VW883_001962"
     CDS             515..715
                     /locus_tag="VW883_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0275039.1"
                     /translation="MSKLRGYRVMLGLTQQQMADKLKISLQSYNNKELGKTPFNDKER
                     LAIKSMVAEIKPDITIDEIFYS"
     gene            900..1328
                     /locus_tag="VW883_001963"
     CDS             900..1328
                     /locus_tag="VW883_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275040.1"
                     /translation="MGKKHQVVKFKDIAEKLPELEGKNLEEIAGVLGYRNLESCRVNL
                     YNLRQNKRLGFEVEKGVYTKFELLDDTVKEELEEKELSERGHFLQSLDYYKVAKNAFE
                     IAEDKTVKAETRQKAERDILDAMKHIPKKHRAILYDMMEG"
     gene            1675..2127
                     /locus_tag="VW883_001964"
     CDS             1675..2127
                     /locus_tag="VW883_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275041.1"
                     /translation="MTETTYDIIAKSLDRISMELHQADENNDFLRIGLLSGQLKAIKE
                     NLHRLLWIELPELNESHKIEAVSKSTTGIFFHPGIFEMDAMRQAFFKRQAKHFFDNAT
                     EQQEYIEYAEKEYLEATKILKDILFNTNNGTRQVNKDCLVEKFEEAMQ"
     gene            2124..2303
                     /locus_tag="VW883_001965"
     CDS             2124..2303
                     /locus_tag="VW883_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275042.1"
                     /translation="MTQSEFYNRMTKIKDRHPNLFQFIIDFLDDKVSTEEVYDFLKME
                     RSYQVNHIKNYKARA"
     gene            2305..2520
                     /locus_tag="VW883_001966"
     CDS             2305..2520
                     /locus_tag="VW883_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275043.1"
                     /translation="MNELDLSNTQAVFVSVVLIGILLYLNHRDRKKSAQIERENQQTI
                     ETPSDDLNPDYGRYIQLAGVRVSGGME"
     gene            2517..2810
                     /locus_tag="VW883_001967"
     CDS             2517..2810
                     /locus_tag="VW883_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275044.1"
                     /translation="MSYTVKIYLDFEKIPDETYFTKEIFLAMCTDNATKLAVTMGLLA
                     KQALDLETRAVILKTLNTIIENQKAILQGVASGQITFLNKSKGEEELDESIRE"
     gene            2791..3132
                     /locus_tag="VW883_001968"
     CDS             2791..3132
                     /locus_tag="VW883_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0275045.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGLEISLTTKLTERTVQDIIKR
                     LIIKHNIPIVGVRNGFYRGYFIPRNKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            3125..3397
                     /locus_tag="VW883_001969"
     CDS             3125..3397
                     /locus_tag="VW883_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275046.1"
                     /translation="MFSLSRESEKDLTHGILEVVERYLEAHEKVPPRLTKLINRIELK
                     EELKISDNTLNKWESQGLRRYQPPDDGSRMIYYLVTDIWKFLGVDE"
     gene            3394..3909
                     /locus_tag="VW883_001970"
     CDS             3394..3909
                     /locus_tag="VW883_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001263812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275047.1"
                     /translation="MRVIELILSADKLPLFGFLKSTPTQVWKNGEHYKFIYFEPIGEG
                     LTAFHYKGLYVAVKDENEEVEGWELTRDLEIGLASPDLLMILKNLEVNKLTEQRQGLG
                     VELKGWVFNLICNGIYTRYETSLFVRLLFVNGYSFSQLVDLFSAIVKRKDLASYFLEV
                     ATKFYKEVAFE"
     gene            3902..5353
                     /locus_tag="VW883_001971"
     CDS             3902..5353
                     /locus_tag="VW883_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HEV0275048.1"
                     /translation="MNSNDIVNKIIEENQQEAPPEVVDLTQARKTNEEHNSLNLAKRP
                     RGDGFDRGLDNLRKILSGDSKLKGAIQYNTFTYEIEVTRPMKLNGRTLNGAIDDLIIR
                     EIRAYIATKYKLDYKKPDIADFLEIVAGENSYNPLKDYLESCESEYKELVNQREPFDI
                     LRHYLNIKDDEYNRIIMDLFFRGAVAKVFDPTVKFDFVLDLTGRQGVGKTQFFEGLFT
                     HKYFTTVETFTDKDDKARMVRNWCVFDDEMVASKKASFSELKKFITETKLEFRPPYAS
                     SDRRLPKSFIIVRATNDHDYLNDLTGERRFLVVEVHKDTAYKGRKWTEKDRRAFWGAM
                     VVAWRANQVLNLTDEQEKLVNEVRSRYKFVDEILEDLERYLDTPYPKRMYQFPMTDRM
                     RYYYIYDMMNEGYYRNNRGGTVELDTDTYGELVDRDKMTINLFFQEVYLTDKAPPKDK
                     AKVKKYMQNRDGWEHRRSTRFGKSIKPAYVKKM"
     gene            5892..6056
                     /locus_tag="VW883_001972"
     CDS             5892..6056
                     /locus_tag="VW883_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HEV0275049.1"
                     /translation="MNPNKDYTPFLQDNFIIFNKNGIIEMKKIPDFGSVVFTSQDGNI
                     VQIETTIKER"
     gene            6210..>6761
                     /locus_tag="VW883_001973"
     CDS             6210..>6761
                     /locus_tag="VW883_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275050.1"
                     /translation="METLQTIETKIDKLIEQNKKAIEMTEAELVKASQAISDAQVKLV
                     QAQEEINSEKYVEAKSDLWTAERTKEFHEGRLKELVTTPIISYDEYHATVKEIYRLAD
                     EQQNTFFTPAVAKLLEIVKLGDESAKEVGKVNEIFRKLEKDISKNNEDYKRDKNGGWF
                     RGPFSSLSYSPRNALHGYQDDLKE"
BASE COUNT         2449 a         1083 c         1476 g         1753 t
ORIGIN      
        1 tctctaccat cagctgtttt tagttcatag tatgctctaa atgctttaaa aaatacttca
       61 tcagagccat ctttttgact taaatttttt acagattcaa taaaattgtt ttcataaccg
      121 agtaagttag caacgcttac cccgaagtaa tcagcaagta gttgggcttt ttctggttta
      181 atttggcttt ctccgttttc cattcgttgg aatgacctta aagaaaatcc caaagtttca
      241 gctatttctt tttgagatag ctttttttct tgtcttaatt ctttcaatct attcatgttt
      301 tatcacacct ttcacagatg attataacct tatgtttaaa aaaagtcaaa aaatgacgta
      361 aaaaaatcaa aaaaactatt gacaacgtct aaaactgacg ttataataaa aatcaagctt
      421 atgttgcgtc ataaaatgac gtcaagcacc ccctccaacc tttcacactt tcaatctatt
      481 catggagggg gattttttag aaaggagcaa atctatgagc aaactacgag gctatcgggt
      541 tatgttagga ctaactcagc aacaaatggc ggacaagcta aaaatttctt tgcagtcgta
      601 caacaacaaa gaattaggta aaacgccatt caatgacaaa gaacgtctag cgattaagtc
      661 aatggttgca gaaatcaaac cagacataac aatagacgaa atattttata gttagaaagg
      721 agcgaactaa tcgcaatact actctatatt tacagatttc tcatgtggtg ctttaccact
      781 ggggattgac aacaaaaaag tcacttgctg aatgtttggc gacagaagca agcgactgga
      841 tcaagagtat agatattttt tctatacctt gattatagca tagaaagaca aggtaaacaa
      901 tgggaaagaa acatcaagta gtaaaattta aagatatagc tgaaaaattg cctgaattag
      961 aaggtaaaaa tttagaagaa atcgctggag tattaggcta ccgcaacttg gagagttgca
     1021 gggtcaacct ttacaatctc agacaaaaca agcgtctagg gtttgaagta gaaaaagggg
     1081 tttacactaa gttcgaactc ttggacgata ctgtaaaaga agaactggaa gaaaaagaat
     1141 tgtctgaacg tggtcatttt ttacagtcgc tagactacta caaagtagca aaaaacgcct
     1201 ttgaaatagc agaagataaa acagtaaaag cagaaacccg acaaaaagca gagcgtgaca
     1261 tattggacgc gatgaagcac attcctaaaa aacatcgcgc tatactttat gacatgatgg
     1321 agggctagga tggaagcaaa aacccacttc gctagattca tgcgtagagg catggagtta
     1381 gcaaggcaat tacatagtaa agaaattcaa cgtgatgaat ttgatagagc ctggaaaaga
     1441 ttaggcgatt aaatcgaaaa cgaaacgaag aaaaactaag aaaaccgaag agcaggcaag
     1501 caattagaaa aggttttgaa atcgagtgct gacacgacga ttctaagcac ttgtttagaa
     1561 aaaatgtggg tgattaccca cgaaacatca ctacaagcgt ccgccaactt ggggcaaatg
     1621 cccagcgttt ggagtggtga aataatccaa tataggaaaa agggaaaaca gactatgaca
     1681 gaaacaacat acgatattat cgctaaaagc ttggatagaa ttagtatgga attacaccaa
     1741 gcagacgaaa acaatgattt tttgagaata ggactcttat caggacaatt aaaagctatc
     1801 aaagaaaatt tacaccgctt actttggatt gagcttcctg aattgaatga aagtcataaa
     1861 atcgaggcag tctctaaaag tactactgga atctttttcc atccaggtat ttttgagatg
     1921 gatgcaatga gacaagcatt ctttaaacgt caagccaagc atttttttga caatgcaaca
     1981 gagcaacagg agtatataga atatgctgaa aaggagtatt tagaggctac taaaatcttg
     2041 aaggatatcc tttttaacac taataatggg actagacaag taaataaaga ttgtcttgta
     2101 gaaaaatttg aagaggcaat gcaatgacac aatcagaatt ttacaaccga atgactaaaa
     2161 tcaaggatag acatccgaac ctctttcagt tcatcattga ctttttagat gataaagtaa
     2221 gcaccgaaga ggtgtatgat tttctgaaga tggagcgaag ctatcaagta aatcatatca
     2281 agaattacaa agcgagagca taacatgaac gaactagatt taagcaacac acaggcggtt
     2341 tttgttagcg tggtactgat tggcatactg ctttatctaa accaccgaga ccgcaaaaaa
     2401 agcgcccaaa ttgagcgaga aaaccaacag acgatagaaa cacctagcga tgatttaaac
     2461 cctgattatg ggcgatatat ccagcttgca ggggtaagag tttccggagg gatggaatga
     2521 gttacacagt gaagatatac cttgattttg aaaaaatacc agatgaaacc tattttacta
     2581 aagagatttt tctagctatg tgtacggaca atgcaacaaa gttagctgta actatgggtt
     2641 tgctggcaaa acaagcgttg gatttagaga ctagggctgt tattttaaaa acccttaata
     2701 caatcataga aaatcaaaaa gctattttgc aaggggtagc gagcggacaa ataacctttt
     2761 tgaataaaag taaaggagag gaggaactgg atgagtctat cagagaatga caagcgagtt
     2821 ttaagactaa tcaaggtagg ggctgagaac tccataacag ggttagaaat cagcctgaca
     2881 accaagctaa cagaaagaac cgtgcaagat attattaagc gtttaataat caagcataac
     2941 atcccaattg tgggggttag aaatggattt tatagaggtt atttcatacc tagaaacaaa
     3001 ggcgagttac tagatggtgc taaggctttt tacaaccaag tacaggagga gagcaagcgc
     3061 ctagcggtgt tgatgaatag cgatttagaa agctacaaag aaaccttgaa ggaggtgggc
     3121 ggatatgttt agcctaagcc gagaaagcga gaaagaccta acgcatggca ttctggaggt
     3181 agtggaaaga tacctggaag cgcatgagaa agtaccgcca agattgacca agttaataaa
     3241 taggattgaa ctcaaagagg aattgaaaat tagtgacaac acgctgaata agtgggaaag
     3301 tcagggttta agacgctatc aaccgccgga cgatggttca agaatgattt actatttagt
     3361 aactgacatc tggaagtttc tgggggtgga tgaatgaggg tgatagagtt aattttatcc
     3421 gctgacaaat tgcctttgtt tggctttctc aagtctacgc caacccaagt ttggaagaat
     3481 ggggaacact acaaatttat ctattttgag ccaataggcg agggcttgac ggctttccac
     3541 tacaaaggtt tgtatgtggc agttaaagac gaaaacgagg aagtagaggg ctgggaacta
     3601 accagagatt tagaaatagg tttggctagt cctgacttgc tgatgatcct gaaaaattta
     3661 gaggtaaata aattgacaga gcaacggcag gggcttggag tggagttaaa aggctgggtt
     3721 tttaacctga tttgtaacgg catttatacc agatatgaga cttcgctttt tgtccgcttg
     3781 ctatttgtca atggctacag ttttagtcag ctggtggact tgttttcagc aatcgtcaaa
     3841 cgcaaagacc tagcaagcta ctttctagaa gtagcgacaa aattctataa ggaggtggct
     3901 tttgaatagc aatgacattg taaataaaat cattgaagag aatcagcaag aagcaccgcc
     3961 tgaagtggtg gacttgaccc aagcaaggaa aaccaacgag gaacacaata gcctgaactt
     4021 ggcaaagaga ccaagagggg acggctttga tagaggttta gacaatctga gaaagatttt
     4081 gagcggagat agcaagctaa aaggggcgat acagtacaac acttttacat atgaaattga
     4141 agtgactaga ccaatgaagc taaacggtag aaccctgaac ggtgcaatcg atgacctgat
     4201 tatcagagag attagggctt atattgctac caagtataag ctagactata aaaagcctga
     4261 tatagctgat tttttggaga tagtggctgg agaaaatagc tacaacccct taaaagacta
     4321 tctggaatct tgcgaaagcg agtataaaga gttagtgaat caacgtgagc cctttgatat
     4381 tttaaggcat tatcttaata tcaaggatga cgaatataac cgtattatca tggatttgtt
     4441 tttccgtgga gcggttgcca aggtgtttga ccctaccgtt aagtttgact ttgtgctgga
     4501 cttgactgga aggcagggag taggaaagac acaatttttt gaggggcttt ttactcacaa
     4561 gtattttaca accgttgaga cattcacaga caaagacgac aaggctagaa tggtgagaaa
     4621 ctggtgtgtc tttgatgatg agatggtggc cagtaaaaag gctagttttt cagaattgaa
     4681 gaaattcatc acagaaacca agctagagtt tagaccccct tacgcttcca gtgacaggcg
     4741 attgcctaag agttttatca ttgtcagagc aactaatgac catgattatt tgaacgacct
     4801 gacaggggaa aggcgctttc tagttgtaga agtccacaag gacaccgcct ataagggcag
     4861 gaaatggaca gagaaagacc gcagagcctt ttggggcgct atggtagtag cttggagggc
     4921 taaccaagtc ttgaacctga cggacgagca ggaaaagcta gtaaatgagg ttagaagtcg
     4981 ttacaagttt gtagatgaaa ttcttgagga tttggagcgc tatttagata ctccttaccc
     5041 aaaaagaatg tatcagttcc cgatgaccga cagaatgcgc tactattata tctatgatat
     5101 gatgaacgag ggatactata gaaataacag gggtggaaca gttgaacttg acacagacac
     5161 ctatggcgaa ctggtagata gggacaagat gaccattaac ctattttttc aagaggtgta
     5221 tttgactgac aaagcaccgc caaaggataa ggctaaggtt aaaaagtata tgcaaaaccg
     5281 agacggctgg gaacataggc gatcaacaag atttggtaaa agtattaaac cagcttacgt
     5341 taaaaaaatg tagtcagtgt agtttatttt taaaagtgac tacattttaa acaggaagaa
     5401 aacccttgat acataagggg ttagaaaaaa gtgttgtttt tactatttta ctgactacac
     5461 ccctaaaccc ttggtattat tgacttttat ataaaaatgt agttattttc tatttattaa
     5521 agagtatatg aagataagag ataaaaggcg tttattgttt atttttttgg gagcaaggtg
     5581 actacatgac tacgcatggc gaaaagcctt gtgactgtaa ggcggagagc gtagtcacta
     5641 gatatcctaa aatgactaca ctttttggaa ttgtgaggag gagacctaaa aagaaatgga
     5701 aatagtaact taaatgagta acttttaaga ctgaaatcat atttgtattt tacataatga
     5761 gaaaatgtaa ataggaaatc acaaaaatag ccctcctccc ttgatagaca aggcgagaag
     5821 ggaggtcgct taaatttaac agaatagaag atatgttaaa tatatggcac caaaaaagag
     5881 aggaaaaaca gatgaatcca aacaaagatt acactccatt tctacaggat aactttatta
     5941 tctttaacaa aaatggtata atagagatga agaaaatacc agactttggt agcgtggtat
     6001 ttactagtca agatggcaac attgtccaga ttgaaacaac aattaaagaa agatagctga
     6061 ctagacaact agaggcgtaa cattaaagct aagtagcttt tttgttgcgt ctctttttgt
     6121 tttgagaaag aggaagtaat gaggaataaa gacccagtaa agagttgaaa ccaataagca
     6181 caatcaaaag aaatgaggaa taaaagaaca tggaaacatt acaaactatt gaaactaaaa
     6241 ttgacaaact gattgaacag aataagaaag ctattgagat gactgaggcg gaactggtta
     6301 aagcaagcca agctatttca gacgcccaag tcaagctagt acaggctcaa gaagaaataa
     6361 actctgaaaa atacgtcgag gcaaaaagtg acctatggac ggcagaacgt acaaaggaat
     6421 ttcatgaggg acgtttgaaa gaattagtta caactccaat aatttcatat gatgaatatc
     6481 acgcaacggt taaagagatt tatagattgg ctgatgaaca acaaaatact ttctttactc
     6541 cagcagtagc caaactattg gaaattgtaa agctgggtga tgagtccgcc aaagaagttg
     6601 gtaaagtaaa cgagatattt agaaaacttg aaaaagatat ctctaaaaat aacgaagatt
     6661 ataaaaggga caaaaacggt ggatggtttc gtgggccatt ttcaagttta tcctattctc
     6721 caagaaacgc cttacatggg tatcaagatg atttaaaaga a
//
LOCUS       DAVKXA010000073         6742 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKXA010000073 DAVKXA010000000
VERSION     DAVKXA010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.073"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1..409
                     /locus_tag="VW883_001974"
                     /pseudo
     CDS             1..409
                     /locus_tag="VW883_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            576..776
                     /locus_tag="VW883_001975"
     CDS             576..776
                     /locus_tag="VW883_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275051.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            818..1222
                     /locus_tag="VW883_001976"
     CDS             818..1222
                     /locus_tag="VW883_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275052.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1453..2160
                     /gene="ccdA2"
                     /locus_tag="VW883_001977"
     CDS             1453..2160
                     /gene="ccdA2"
                     /locus_tag="VW883_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0275053.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFQYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2171..2728
                     /gene="sdbB"
                     /locus_tag="VW883_001978"
     CDS             2171..2728
                     /gene="sdbB"
                     /locus_tag="VW883_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0275054.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3102..4493
                     /locus_tag="VW883_001979"
     CDS             3102..4493
                     /locus_tag="VW883_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0275055.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGITFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4636..5553
                     /gene="adcAII"
                     /locus_tag="VW883_001980"
     CDS             4636..5553
                     /gene="adcAII"
                     /locus_tag="VW883_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0275056.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5561..>6742
                     /gene="phtB"
                     /locus_tag="VW883_001981"
     CDS             5561..>6742
                     /gene="phtB"
                     /locus_tag="VW883_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV0275057.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQSRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FE"
BASE COUNT         2077 a         1236 c         1419 g         2010 t
ORIGIN      
        1 ctgaaatagc ttctgaattt ggctgtcatc caactaccat cactatgcgt tcaaagctat
       61 gggctacact cgaaaaaaag aaccacacct actatgaaca agacccagaa aagtagcctt
      121 atttcttaag aattttaata gtttaaagca cctagcacct gtttagattg atgaaacagg
      181 attcgatact tatttttatc gagaatatgg tcgctcatta aaaggtcagt taataagagg
      241 caaagtatct ggaagaagat atcagaggat ttctttggtt gcaggtctaa caaatggtga
      301 attaatcgct ccaatgactt acgaagagat gatgacgagc gacttttttg aagtatggtt
      361 tcagaagttt ctcttaccaa cattaaccac accatcggtt attatagtaa aatgaaataa
      421 gaacaggaca aatcgatcag gacagtaaaa tcgaattcta acaatgtttt agaagtccat
      481 atgtactatt ctagtttcaa tataccataa ctgttcctag tcaacctgca agccctgtcc
      541 cagctccaag ctcagctccg actcaagatc ctagagtggt agcaagcgct tcggctagct
      601 caacgagcac acaagctcaa gagcaagttg acaagtctga acttcgtgcc ttgagtcaag
      661 agttagacca acgcttgaaa gctttggcaa cagtatctga tccgaaaatc gatgcaacca
      721 aggctgtcct cctagatgct caaaaagctc cggaagatag tgccttgaca gagtaaggtc
      781 tgcatactgc agtagagtct gtgaaggctg ggctgccttg gactctctca aagatgtgaa
      841 agcaaatgct agcgacagca agcctgcaca ggacaagaag gatgcaaaac aaggaacgga
      901 agatagtaag gattcagata agatgactga aacaaactca gttccggcag gagtgattgt
      961 ggtcagtcta cttgccctcc taggcgtgat tgccttctgg ctgattcgcc gtaagaaaga
     1021 gtcagaaatc cagcaattaa gcacggaatt gatcaaggtt ctaggacagc tagatgcaga
     1081 aaaagcggat aaaaaagtcc ttgccaaagc ccaaaacctt ctccaagaaa cccttgattt
     1141 cgtgaaagaa gaaaatggct cagcagagac agaaactaaa ctagtagagg agcttaaagc
     1201 aatccttgac aaactcaagt aaaacatgat ttatgaaatg tcagacctaa aagacatttt
     1261 cgttcacaaa agcagcgatg agtaatcctt gtcgttgctt tttggctatt ttgggggata
     1321 agatccgcct tgactagcaa aagaaaagat tggtccaata gtgcccgata cgattttgcg
     1381 tagcagaaag cttacaaata aaattgaata tagtaaaata ggattagaat tattaagaaa
     1441 gttggttctt tattggaaac gatagtattt ttaatctctg tttttctagc aggtgtttta
     1501 tccttttttt ctccttgtat ttttcctctt ctgccagtct atgctgggat tttattggat
     1561 gatcaagaaa gtgcaaaaag cttttctttg tttgggagaa aggttctctg gtcaggcttg
     1621 attcgaacac tttgctttat cgctggtatc tctctcattt tctttattct aggctttggt
     1681 gctggttact ttggtcatat tctctatgca aattggtttc aatatggcat gggagctatt
     1741 attatcattt tgggtcttca ccagatggaa atttttcatt tgaagaaatt agaagttcaa
     1801 aaaagtttta cctttaaaaa atcagattct aatcgttatt ggtcagcttt tttacttggt
     1861 attaccttta gctttggttg gacaccttgt attggtccag ttttaagttc tgttttagca
     1921 cttgcggctt ctggaggcaa tggcgcttgg caaggagcga tttatactct catttacact
     1981 ctgggcatgg cccttccttt cttggtattg gcactagctt caggtctagt catgccatat
     2041 tttagtaaaa tcaagcgtca tatgatgcta ctaaagaaaa ttggtggttt cctcattgtt
     2101 ttaatgggaa ttttgttact attaggacaa gtaaatgttc tagctggaat ttttgaataa
     2161 aggaggacaa atgaaaaaag taatgtttgc tggcttaagt ctcttgtcat tagttgtatt
     2221 gatggcctgt ggtgaggaag aaactaaaaa gactcaagca gcacaacagc caaaacaaca
     2281 aacgactgta caacaaattg ctgttggaaa agatgctcca gacttcacat tgcaatccat
     2341 ggatggcaaa gaagttaagt tatctgattt taagggtaaa aaggtttact tgaagttttg
     2401 ggcttcatgg tgtggtccat gcaagaaaag tatgccagag ttgatggaac tagcggcgaa
     2461 accagatcgt gatttcgaaa ttcttactgt cattgcacca ggaattcaag gtgaaaaaac
     2521 tgttgagcaa ttcccacaat ggttccagga acaaggatat aaggatatcc cagttcttta
     2581 tgataccaaa gcaaccacct tccaagctta tcaaattcga agcattccta cagaatattt
     2641 aattgatagc caaggaaaga ttggaaagat tcaatttggt gctatcagta atgcggatgc
     2701 agaagcagca tttaaagaaa tgaactagaa tcgataaaat ctgattacaa gatgtagtca
     2761 gattttggta acttctaaaa ctaacttcca gtttcccaca acctagcttt tagtatgaga
     2821 aaaacgcgtg acatcagtgg aaatccgtct tagactaact tccactggtt ttctttttct
     2881 tgatatataa gggttcaaaa gcgaaaagac tcagaaaaag tgcacgacaa atagccctaa
     2941 aacagagtcg tcttagagta acttccagtt ttgggagaga gatggaagtt actttgagaa
     3001 gttacggtag tcagattttt ttagaaaaac attttataaa tattcacata tctcctatat
     3061 ttatggtaaa atagaattat cagtttattt tggagtcaaa gatgaatata tttagaacaa
     3121 agaatgttag tttagataaa acagagatgc ataggcattt gaagttatgg gatttgattt
     3181 tgctgggtat cggagccatg gtagggacag gcgtctttac aatcacaggt actgcagctg
     3241 caacacttgc tggcccagcc ctagtgattt caatcgttat ttctgccttg tgtgtgggat
     3301 tatcagccct cttttttgca gaatttgcct cgcgagtacc cgctacagga ggtgcctata
     3361 gttacctcta tgctatctta ggagaattcc ctgcctggtt ggctggttgg ttaaccatga
     3421 tggagttcat gacagccata tcaggcgtag cttcgggttg ggcagcttat tttaaaggct
     3481 tgctctctca atacgggata acctttcctc aggctttaaa tggtaccttt aatcctcaag
     3541 cagggacatt tgttgattta ttgcctattc ttgtcttggt cttggtgact tcgcttgttt
     3601 tactaaatgc caaggcagcc ttacgcttta attcgattct agttattttg aaattttccg
     3661 ctttagctct ctttgtttta gtaggaattt ggaatattaa gtttgataat tggagcaatt
     3721 ttgctcctta cggttttgga caaatctatg gagctagcac tggtattatg gctggtgcgt
     3781 ccttgatgtt cttcggtttt ttgggatttg aatccatctc tatggctgta gatgaagtca
     3841 agactcctca aaaaaatatt cctagaggga ttgtcttatc gctttctatc gtaaccattc
     3901 tctatgcctt ggtgaccctt gttttgactg gtgtggttca ctatagtcat ttaaatgtcg
     3961 atgatgccgt tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc aactatgtgt
     4021 cattagtggc tatcttgacc ttgattacag tttgtatttc gatgacctat gccctatcgc
     4081 gtatgattta cagtttagca cgtgacggct tagtgcctgc tgcctttaag gaactgacga
     4141 agactagcaa gataccaaag aatgctacta tcttgacagg tctagcttca gcagtagcag
     4201 caggaatgtt cccactagcc agtattgcag cctttttaaa tatttgtacc ttagcctact
     4261 tgatcatgtt ggcttatggt ctgattcgct tacggaaaga aaaaggaatg cccaaagctg
     4321 gggaatttaa aacaccattg gtacctctgt taccaatttt atcgatcatc atttgtttat
     4381 ccttcatgtt acagtataat atgaatacct ggattgcttt cctagttgcg ttgttagtag
     4441 gaagtattat ttacttcact tatggctata agcattctac catagaagaa taaagtgaaa
     4501 gtctattgag ttgttgacac tcagcagatt tttatatgtg aaagaaattt caaatttttt
     4561 ctaaaaatat cttgacagat taaattttca ggagtagaat atttactagt taattaaatg
     4621 gttaaggagt tgttcatgaa gaaacaaaat ttatttttag tcctgttaag tgtctttctt
     4681 ttgtgcttgg gggcttgtgg tcaaaaggaa agtcagacag gaaaggggat gaaaattgtg
     4741 accagttttt atcctatcta cgctatggtt aaggaagtat ctggtgactt gaatgatgtt
     4801 cggatgattc agtcaagtag tgggattcac tcctttgaac cttcggcaaa tgatatcgca
     4861 gccatctatg atgcagatgt ctttgtttac cattctcata cactcgaatc ttgggcagga
     4921 agtctggatc caaatctaaa aaaatccaaa gtgaaggtct tagaggcttc tgagggaatg
     4981 accttggaac gtgtccctgg actagaggat gtggaagcag gagatggagt tgatgaaaaa
     5041 acgctctatg accctcacac atggctagat cctgaaaaag ctggagaaga agcccaaatt
     5101 atcgctgata aactttcaga ggtggatagt gagcataaag agacttatca aaaaaatgcg
     5161 caagccttta tcaaaaaagc tcaggaattg actaagaaat tccaaccaaa atttgaaaaa
     5221 gcgactcaga aaacatttgt aacacaacat acagcctttt cttatctagc gaagagattt
     5281 gggcttaatc aacttggtat tgcaggtatc tctcctgaac aagaaccaag tccacgacaa
     5341 ctaacagaaa ttcaggaatt tgttaagacc tataaggtta aaacgatttt tacagaaagt
     5401 aacgcttctt caaaagtagc tgaaactctt gtcaaatcaa caggtgtggg tcttaaaact
     5461 ctgaatcctt tagagtcaga cccacaaaat gacaagacct atttagaaaa tcttgaagaa
     5521 aatatgagta ttctagcaga agaattaaag tgaggaaaga atgaaaatta ataaaaaata
     5581 tctagcaggt tcagtggcag tccttgccct aagtgtttgt tcctatgagc ttggacgtta
     5641 ccaagctggt caggataaga aagagtctaa tcgagttgct tatatagatg gtgatcaggc
     5701 tggtcaaaag gcagaaaatt tgacaccaga tgaagtcagt aagagagagg ggatcaacgc
     5761 cgaacaaatt gttatcaaga ttacggatca aggttatgtg acctctcatg gagaccatta
     5821 tcattactat aatggcaagg ttccttatga tgccatcatc agtgaagaac ttctcatgaa
     5881 agatccgaat tatcagttga aggattcaga cattgtcaat gaaatcaagg gtggctatgt
     5941 gattaaggta gacggaaaat actatgttta ccttaaagat gcggcccatg cggacaatat
     6001 tcggacaaaa gaagagatta aacgtcagaa gcaggaacgc agtcataatc ataactcaag
     6061 agcagataat gctgttgctg cagccagagc ccaaggacgt tatacaacgg atgatgggta
     6121 tatcttcaat gcatctgata tcattgagga cacgggtgat gcttatatcg ttcctcacgg
     6181 cgaccattac cattacattc ctaagaatga gttatcagct agcgagttag ctgctgcaga
     6241 agcctattgg aatgggaagc agggatctcg tccttcttca agttctagtt ataatgcaaa
     6301 tccagctcaa tcaagattgt cagagaacca caatctgact gtcactccaa cttatcatca
     6361 aaatcaaggg gaaaacattt caagcctttt acgtgaattg tatgctaaac ccttatcaga
     6421 acgccatgtg gaatctgatg gccttatttt cgacccagcg caaatcacaa gtcgaaccgc
     6481 cagaggtgta gctgtccctc atggtaacca ttaccacttt atcccttatg aacaaatgtc
     6541 tgaattggaa aaacgaattg ctcgtattat tccccttcgt tatcgttcaa accattgggt
     6601 accagattca agaccagaac aaccaagtcc acaaccgact ccagaaccta gtccaagtcc
     6661 gcaaccagct ccaagcaatc caattgatga gaaattggtc aaagaagctg ttcgaaaagt
     6721 aggcgatggt tatgtctttg ag
//
LOCUS       DAVKXA010000074         6702 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKXA010000074 DAVKXA010000000
VERSION     DAVKXA010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.074"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..1077
                     /gene="dnaN"
                     /locus_tag="VW883_001982"
     CDS             <1..1077
                     /gene="dnaN"
                     /locus_tag="VW883_001982"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0275058.1"
                     /translation="AISSKNVIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNED
                     AGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQ
                     YPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVAT
                     DSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIEAVEIFFANNQILFRSENI
                     SFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKD
                     GVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAV
                     RPFTLVPADTDEDFMQLITPVRTN"
     gene            1142..1336
                     /locus_tag="VW883_001983"
     CDS             1142..1336
                     /locus_tag="VW883_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0275059.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1420..2535
                     /gene="ychF"
                     /locus_tag="VW883_001984"
     CDS             1420..2535
                     /gene="ychF"
                     /locus_tag="VW883_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0275060.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2606..3175
                     /locus_tag="VW883_001985"
     CDS             2606..3175
                     /locus_tag="VW883_001985"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0275061.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3176..6685
                     /gene="mfd"
                     /locus_tag="VW883_001986"
     CDS             3176..6685
                     /gene="mfd"
                     /locus_tag="VW883_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0275062.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGFGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
BASE COUNT         2270 a         1020 c         1365 g         2047 t
ORIGIN      
        1 gctattagtt ctaaaaatgt cattcctatt ttatcaacag taaaaattga cgtgaccaat
       61 gaaggtatta ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt tatttctcaa
      121 aaaaatgaag atgctggttt gttaattact tctttaggtt cgatccttct tgaagcttct
      181 ttctttatca atgtagtatc tagtttacct gatgtaactc ttgattttaa agaaattgaa
      241 caaaatcaaa ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg aaaagatagc
      301 gaacaatatc cacgaatcca agaaatttca gcaagcactc ctttaatact tgaaacaaaa
      361 ttactcaaga aaattattaa tgaaacagcc tttgctgcaa gtacacaaga gagtcgtccg
      421 attttaacag gtgtccactt cgtattgagt caacacaaag agttaaaaac agttgcaaca
      481 gactctcatc gcctaagcca gaaaaaattg actcttgaaa aaaatagtga tgattttgat
      541 gtcgtaattc ctagccgttc tctacgcgaa ttttcagcgg tatttacaga tgatatcgaa
      601 gctgtagaga ttttctttgc caataaccaa atcctcttta gaagcgaaaa tattagcttc
      661 tatactcgtc tcctagaagg aaactatcct gatacagatc gcttgattcc aacagacttt
      721 aacactacta ttacttttaa tgtggtaaac ttacgccagt caatggagcg tgcccgtctt
      781 ttatcaagtg cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg ggttgttagc
      841 gcccatgttc actctccaga agttggtaaa gtaaacgaag aaatcgatac tgatcaggtt
      901 actggtgaag atttgaccat tagtttcaac ccaacttact tgattgattc tcttaaagct
      961 ttaaatagcg aaaaggtgac cattagcttt atctcagctg ttcgtccatt tactcttgtg
     1021 ccagcagata ctgacgaaga cttcatgcag ctcattacac cagttcgtac aaattaagtg
     1081 aaagaggttg agcctggctc gcctctttta tgatataatc gaaaaagaaa aggagagtag
     1141 tatgtatcaa gttggaaatt ttgttgagat gaaaaaatca cacgcttgta caatcaagtc
     1201 gactggtaaa aaggctaatc gttgggaaat tacacgtgta ggagcagata tcaaaataaa
     1261 atgcagtaat tgtgagcatg ttgtcatgat ggggcgatat gattttgagc gaaaaatgaa
     1321 taaaattatt gactgagaac ccttagttag agggttagca ctttatccct ttttgtgtta
     1381 taatattagg gattgaaatg aaaacggaga atgagaaata tggctttgac agcaggtatc
     1441 gttggtttgc caaacgttgg taaatcaaca ctatttaatg caattacaaa agcaggagca
     1501 gaggcagcaa actacccatt tgcgactatt gatccaaatg ttggaatggt ggaagttcca
     1561 gatgaacgcc tacaaaaact aactgaaatg ataactccta aaaagacagt tcccacaaca
     1621 tttgaattta cagatattgc agggattgta aaaggagctt caaaaggaga agggctaggg
     1681 aataaattct tggccaatat tcgtgaagta gatgcgattg ttcacgtagt tcgtgctttt
     1741 gatgatgaaa atgtaatgcg cgagcaagga cgtgaagacg cctttgtaga tccacttgca
     1801 gatattgata caattaatct ggaattaatt cttgctgact tagaatcagt gaacaaacga
     1861 tatgcgcgtg tagaaaagat ggcacgtacg caaaaagata aagaatcagt agcagaattc
     1921 aatgttcttc aaaagattaa accagtccta gaagacggga aatcagctcg taccattgaa
     1981 tttacagatg aggaacaaaa ggttgtcaaa ggtcttttcc ttttgacgac taaaccagtt
     2041 ctttatgtag ctaatgtgga cgaggatgtg gtttcagaac ctgactctat cgactatgtc
     2101 aaacaaattc gtgaatttgc agcgacagaa aatgctgaag tagtcgttat ttctgcgcgt
     2161 gctgaggaag aaatttctga attggatgat gaagataaaa aagagtttct tgaagccatt
     2221 ggtttgacag aatcaggtgt agataagttg acgcgtgcag cttaccactt gcttggattg
     2281 ggaacttact tcacagctgg tgaaaaagaa gttcgcgctt ggactttcaa acgtggtatg
     2341 aaggctcctc aagcagctgg tattatccac tcagactttg aaaaaggctt tattcgtgca
     2401 gtaaccatgt catatgaaga tctagtgaaa tacggatctg aaaaggccgt aaaagaagct
     2461 ggacgcttgc gtgaagaagg aaaagaatat atcgttcaag atggcgatat catggaattc
     2521 cgctttaatg tctaaaaatt aataaatggt gtcaattagg ttggaaaaaa attccaaccc
     2581 ttttggcttt tgaaaggaaa aataaatgac caaattactt gtaggcttgg gaaatccagg
     2641 ggataaatat tttgaaacaa aacacaatgt tggttttatg ttgattgatc aactagcgaa
     2701 gaaacagaat gtcactttta cacacgataa gatatttcaa gctgacctag catccttttt
     2761 cctaaatgga gaaaaaattt atctggttaa accaacgacc tttatgaatg aaagtggaaa
     2821 agcagttcat gctttattaa cttactatgg tttggatatt gacgatttac ttatcattta
     2881 cgatgatctt gacatggaag ttgggaaaat tcgtttaaga gcaaaaggct cagcaggtgg
     2941 tcataatggt atcaagtcta ttattcaaca tataggaact caggtcttta accgtgttaa
     3001 gattggaatt ggaagaccta aaaatggtat gtcagttgtt catcatgttt tgagtaagtt
     3061 tgacagggat gagtatatcg gtattttaca gtctgttgac aaagttgacg attctgtaaa
     3121 ctactattta caagagaaaa attttgagaa aacaatgcag aggtataacg gataaatggt
     3181 gaccttatta gatttattct cagaaaatga tcagattaaa aaatggcatc aaaatttaac
     3241 agataagaaa agacaactaa tacttggttt atcaacatct actaaggctc ttgcaattgc
     3301 aagcagttta gaaaaagaag ataggattgt gttattgatg tcaacttatg gagaagcaga
     3361 aggacttgtt agtgatctta tatctatctt gggtgaggaa ctcgtctatc catttttggt
     3421 agatgatgct cctatggtgg agtttttgat gtcttcacag gaaaaaatta tttcacgggt
     3481 tgaagccttg cgttttttga ctgattcatc taagaaaggg attttagttt gtaatatcgc
     3541 agcaagtcga ttgattttac cgtctcccaa tgcattcaaa gatagtattg taaaaatctc
     3601 agttggtgaa gaatatgatc aacacgcgtt tatccatcag ttaaaggaaa atggctatcg
     3661 aaaagttact caagtacaaa ctcagggcga atttagtctt cgaggagata ttttagatat
     3721 ttttgaaata tcccagttag aaccttgtcg aattgagttt tttggtgatg aaattgatgg
     3781 tatcaggtca tttgaagtag aaacacaatt atcgaaagaa aataagacag aactcactat
     3841 ctttccagct agtgatatgc ttttgagaga aaaggattat caacgaggac agtcagcttt
     3901 agaaaaacaa atttcaaaaa ctttatcacc tattttgaaa tcatacctag aagaaattct
     3961 ttcaagtttt caccaaaaac aaagtcatgc agactctcgg aagtttttat ctttgtgcta
     4021 tgataagaca tggactgtct ttgattatat tgaaaaagat actccaatat tctttgatga
     4081 ttatcaaaaa ttgatgaatc agtatgaagt ctttgaaaga gaattagcgc agtactttac
     4141 agaagaatta cagaatagta aagcattttc tgatatgcag tatttttctg atattgaaca
     4201 aatctataaa aaacaaagtc cagtgacctt tttttctaat cttcaaaagg gtttaggaaa
     4261 tctcaaattt gacaaaattt atcaattcaa tcaatatcct atgcaggaat ttttcaatca
     4321 gttttctttt ctaaaagaag aaattgaacg atataaaaaa atggattaca ccattattct
     4381 gcagtctagc aattcaatgg gaagtaaaac attggaggat atgttagagg aatatcagat
     4441 taaattggat tctagagata agacaaatat ctgtaaagaa tctgtaaact taatagaggg
     4501 taatctcaga catggttttc attttgtaga tgaaaagatt ttattgataa ctgaacatga
     4561 gatttttcaa aagaaattaa agcgtcgttt tcgaagacaa catgtttcaa atgcagagag
     4621 attaaaagat tacaatgaac ttgaaaaagg ggactatgtt gtccatcata tccatgggat
     4681 tggtcaatat ctaggaattg aaaccattga aatcaaggga attcatcgtg attatgtcag
     4741 tgtccaatac caaaatggtg atcaaatttc tattcccgtg gaacagattc atctactgtc
     4801 caaatatatt tcaagtgatg gtaaagctcc aaaactcaat aaattaaatg acggtcattt
     4861 taaaaaggcc aagcaaaagg ttaagaacca ggtagaggat atagctgatg atttaatcaa
     4921 actctactct gaacgtagtc agttgaaggg ttttgctttc tcagctgatg atgatgatca
     4981 agatgccttt gatgatgctt tcccttatgt tgaaacggat gatcaacttc gtagtattga
     5041 ggaaatcaag agggatatgc aggcttctca gccaatggat cgacttttag ttggggatgt
     5101 tggttttgga aagactgaag ttgctatgcg tgcagccttt aaagcagtca atgatcacaa
     5161 acaggttgtc attctagttc cgacgacggt tttagcgcaa cagcactata cgaattttaa
     5221 ggaacgattc caaaattttg cagttaatat tgatgtgttg agtcgcttta gaagtaaaaa
     5281 agagcagact gcaacacttg aaaaattgaa aaacggtcaa gtcgatattt tgattggaac
     5341 acatcgtgtt ttgtcaaaag atgttgtgtt tgctgatttg ggcttgatga ttattgatga
     5401 ggaacagcga tttggtgtca agcataagga aactttgaaa gaactgaaga aacaagtgga
     5461 tgtcctaacc ttgaccgcta cgccaatccc tcgtaccctc catatgtcta tgctgggaat
     5521 cagagatttg tctgttattg aaactccgcc gactaatcgc tatcctgttc agacctatgt
     5581 tttggaaaag aatgatagtg tcattcgtga tgctgtcttg cgtgaaatgg agcgtggagg
     5641 tcaagtttac tatctttaca acaaagttga cacaattgtt cagaaggttt cagaattaca
     5701 ggagttgatt ccggaggctt cgattggata tgttcatggt cgaatgagtg aagtccagtt
     5761 ggaaaatact ctattagact ttattgaggg acaatacgat atcttggtga cgactactat
     5821 tattgagaca ggggtggaca ttccaaatgc taatacttta tttattgaaa atgcggacca
     5881 tatgggcttg tcaaccttat atcagttaag aggaagagtc ggtcgtagta atcgtattgc
     5941 ttatgcttat ctcatgtatc gtccagaaaa atcaatcagt gaagtctctg aaaagagatt
     6001 agaagcgatt aaaggattta cagaattggg ctttggcttt aagattgcaa tgcgagatct
     6061 ttcgattcgt ggagcaggaa atcttttagg aaaatcccag tctggtttca ttgattctgt
     6121 tggttttgaa ttgtattcgc agttattaga ggaagctatt gctaaacgaa acggtaatgc
     6181 taacgctaac acaagaacca aagggaatgc tgagttgatt ttgcaaattg atgcctatct
     6241 tcctgatact tatatttctg atcaacgaca taagattgaa atttacaaga aaattcgtca
     6301 aattgacaac cgtgtcaatt atgaagagtt acaagaggag ttgatagacc gttttggaga
     6361 atacccagat gtagtagcct atcttttaga gattggtttg gtcaaatcat acttggacaa
     6421 ggtctttgtt caacgtgtgg aaagaaaaga taataaaatt acaattcaat ttgaaaaagt
     6481 cactcaacga ctgtttttag ctcaagatta ttttaaagct ttatccgtaa cgaacttaaa
     6541 agcaggcatc gctgagaata agggattaat ggagcttgta tttgatgtcc aaaataagaa
     6601 agattatgaa attttagaag gtctgctgat ttttggagaa agtttattag agataaaaga
     6661 gtttaaggaa gaaaattcca tttgatattt ttcttctata aa
//
LOCUS       DAVKXA010000075         6126 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKXA010000075 DAVKXA010000000
VERSION     DAVKXA010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.075"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            31..1785
                     /locus_tag="VW883_001987"
     CDS             31..1785
                     /locus_tag="VW883_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0275063.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1769..3490
                     /locus_tag="VW883_001988"
     CDS             1769..3490
                     /locus_tag="VW883_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0275064.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3501..4085
                     /locus_tag="VW883_001989"
     CDS             3501..4085
                     /locus_tag="VW883_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0275065.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     YMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            4085..4780
                     /locus_tag="VW883_001990"
     CDS             4085..4780
                     /locus_tag="VW883_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0275066.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKFKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            4768..>6126
                     /locus_tag="VW883_001991"
     CDS             4768..>6126
                     /locus_tag="VW883_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0275067.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGIKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFE"
BASE COUNT         2220 a          786 c         1149 g         1971 t
ORIGIN      
        1 aaagggatat taaagaaagg agatatgctt atgaagattt acaaaaaact atttgcttat
       61 gtccaagata agaaatatct tggggttttg gccataattt tttctgctat atctgctcta
      121 cttacagtat atggatatta tttaatctac aaatttctag ataagttaat aattaattca
      181 aatttatccg gtgcagagag catagcatta aaatctgtta ttacactaac aagtggagcg
      241 atattttatt ttgtctcagg aatgttttca catatcttgg gattcaggct tgaaacaaat
      301 ttaagaaaaa ggggaatcga tggtctggaa aaagcaagtt ttaggttctt tgacttaaat
      361 ccatctggtc aaataagaaa gattatagat gacaatgctg cacaaactca tcaggtggta
      421 gcacacatga ttcccgatag ttctcaggca ataatcacac ccgtacttgt acttgcactt
      481 ggctttatag taagtataag agttggcata attttgcttg ctcttactat aattggtggc
      541 ttaattttag gggcaatgat gggcgagcaa gaatttatga agatatacca agaatcccta
      601 tctaaactaa gtgctgaaac tgttgagtac gtgagaggaa tgcaagttgt aaaaatattt
      661 aaagcaaatg tagagtcttt taaaagcttt tataaggcga taaaagatta ctcaaagtat
      721 gcttatgatt attccctatc ttgtaaaagg ccttatgttt tgtatcaatg gttatttttt
      781 ggactgattg caattttaat tattcctata gtttatttta tgactagctt agctagcgca
      841 aaggtgattt tacttgagct tatcatgatt ttatttttat caggagttct ctttgtttca
      901 ttcatgagaa tgatgtggta ctccatgtat atttctcaag gaaattatgc agtagatact
      961 ttagaggcgc tttacgaaga tatgcaaaaa gacaaattag tgcatggtaa tatcaataat
     1021 tttaaaaact ataatataga atttgagaat gttagctttg cttataatga taaagctgtc
     1081 attgaaaatt tatcctttaa tttagaagaa ggaaagtcct acgcacttgt cggttcatct
     1141 ggatcaggca aatcaacagt agcaaaactt atatcaggtt tttataatgt taataaagga
     1201 agcataaaga taggcgggat agcaataagt gaatattctg acgaagcctt aattaaagcc
     1261 atttcctttg tttttcaaga ttcaaaatta ttcaagaaga gcatttatga taatgtagct
     1321 ttagctaata aagatgcgac gaaagatgac gttatgagag ccttaaaatt agcaggatgc
     1381 gatttaatat tagacaaatt cccagaaaga gaaaatacaa tcataggctc aaaaggtgtt
     1441 tatttatccg gtggagaaaa acaaagaatt gcaattgcta gagcaatttt aaaggattcc
     1501 aaaattatta ttatggatga agcatcagca tctattgacc cagataacga gtttgaattg
     1561 caaaaagctt ttaaaaatct tatgaaggat aaaacagtta tcatgattgc acacaggcta
     1621 tctacaatta aagaccttga tgaaattatt gtcatggata gtggaaaaat tatagaaaga
     1681 gggtctgaca aagaattaat gtcaaaagat acaaggtata agagcctgca agagatgttt
     1741 aacagtgcga atgaatggag ggtttcaaat gaaagagttt tataaaaaaa gatttgctct
     1801 tacagatgga ggagcaagaa atttaagtaa agcaacactg gcttcatttt tcgtttattg
     1861 tataaacatg cttcctgcca tattacttat gatttttgct caggaagttt tggaaaatat
     1921 gggcaaaagc aatggctttt atatagtatt ctcagttttg actttgatag caatgtatat
     1981 tttgctttct atcgaatacg ataaattata taacacaacc tatcaagaaa gtgcagattt
     2041 aagaataagg acagcggaga atttatcaaa attacctcta tcttactttt ctaaacatga
     2101 catttccgac atttcacaaa caatcatggc tgatattgaa ggcatagagc atgcaatgag
     2161 ccactcaata ccaaaggtgg gcggcatggt actgtttttc ccattaatat ctgtaatgat
     2221 gctagcgggc aatgtcaaga tgggtttagc tgtaattatt ccatctattt taagctttat
     2281 atttatacct ttatctaaaa aatatcaggt taatggacag aatagatatt atgatgtctt
     2341 aagaaaaaac tcagaaagct ttcaagaaaa tatcgaaatg caaatggaga ttaaagcata
     2401 taatttatcg aaggatatta aagacgactt atataaaaaa atggaagata gtgagagaat
     2461 acacttaaag gcggaagtaa ctacaatttt aactttgtct atatcttcaa tatttagctt
     2521 tatatctctt gctgttgtga tatttgtcgg cgtaaatcta attattaata aagagataaa
     2581 ttctctctac cttataggat atttactagc tgctatgaag ataaaagact ctttagatgc
     2641 atctaaagag ggcttgatgg aaatatttta tttatcgccc aaaatagaaa gattaaaaga
     2701 aattcaaaat caagatttac aagaaggcga tgactatagc ttaaaaaaat ttgatattga
     2761 tctaaaagat gttgagtttg cctacaataa agacgcaaaa gttttaaatg gtgtcagttt
     2821 taaagctaag cagggagagg tcactgcttt ggtaggtgca agtggctgcg gtaaaacaac
     2881 tatcttgaaa cttatatcaa gactttatga ttatgacaag ggacaaatct taatcgatgg
     2941 caaagatata aaggaaatat caacagaatc cctttttgat aaggtgtcta ttgttttcca
     3001 agatgtggtt ctctttaatc aaagcgttat ggaaaatatt agaatcggta agcaagatgc
     3061 aagtgacgaa gaggttaaaa gagcagcaaa acttgcaaat tgcacagatt ttatagaaaa
     3121 aatggataaa ggtttcgata cagttattgg tgaaaacgga gctgagctat caggaggaga
     3181 aagacaaaga ttatcaatag ccagagcctt cttaaaagat gcgccgatat tgatcttaga
     3241 tgagataaca gcaagccttg atgttaacaa cgagaaaaag attcaagagt ctttaaataa
     3301 tttagttaaa gataaaactg ttgtaatcat ttcacataga atgaaatcca tagaaaatgc
     3361 agacaagata gtagttcttc aaaacggaag agtagaaagc gaaggtaagc atgaagagct
     3421 tttacaaaaa tcaaaaattt acaaaaattt aatagaaaag acaaaaatgg cagaagaatt
     3481 tatttattag gaggactaca atggataata aaaaattaaa agtaaaagat ttagtaagta
     3541 tcggtgtttt tggcgtaatt tattttgcct tcatgtttgg agttggtatg atgggcttga
     3601 ttccaatatt gttcttaata tacccgacag tattagccat agttgcagga actgttgtta
     3661 tgttatttat ggctaaggtt caaaagccat gggcactatt tatatttggt atgatatcac
     3721 cacttgtgat gtttgcagct ggtcatacct acgtagttgt ggttttatca cttatagtaa
     3781 tgataatagc agaattaatt agaaagattg gtaattataa ttcatttaaa tacaatatgc
     3841 tttcttatgc aatcttcagc acatggatat gtagctcttt aatgcaaatg cttttagcaa
     3901 aagaaaaata tatggagtgg tctttgatga cgatgggaaa agattatgtt gatgtattag
     3961 aaaagttaat aacttatcct tacatggctt tagtagcctt aggtgctttc ttaggaggaa
     4021 ttcttggagc atatataggc aaggctctat tgaaaaaaca ctttgaaaaa gcaggcatcg
     4081 tataatgcct actttttctt caaatgctcc ctttaatccc aatccgatct ctaagatatt
     4141 agtcgtattt atcacaggct taactgttat gcatagcata aacatccgtt ttgagctggc
     4201 aattgtttgt cttattggta ttttgcttta tttgaatgga tacaaaaaaa cacttttcaa
     4261 atggattata ttgtgtggga tactttactc cttgcctaat tttatggtgt tatctgaatt
     4321 aaaccctata gttaagatgt ttttgagtat acctattgtt attagaatgt ttattttacc
     4381 atttatggca gcaagcttta tgataaagac ctcggatgta ggcgcaataa tttcatcgat
     4441 ggataagttt aagatttcaa agaatgtatc catacctatt gcggttatgt ttagattctt
     4501 cccatctttt aaggaggaga agaaaaacat caaaatagct atgagagtaa gagggataaa
     4561 ttttaaaaac ccagtcaaat atcttgaata tgtttctgtg ccactactca ttatatcatc
     4621 taatatatca gatgacattg caaaagcggc agaaacaaag gcaatagaaa atccaattgc
     4681 caagaccaga tacattcgcg taaagataca gctaattgat tttgtttatg ttttagcggt
     4741 tgttggactt attgtgggag gcttaatatg gttgaaataa aaaatttaag tcttgattat
     4801 ggtgaagagc atatattaga tgatatatca ctatccatag ccgagggaga gtgcgtgcta
     4861 tttacaggaa aaagtggaag tggtaagtca tctttaataa attcaatcaa tggactagct
     4921 gtaaggtatg ataacgcaaa gacaaagggc gaaataatta ttgatggtaa gaatataaaa
     4981 aatttggaac tttatcaaat ctcaatgctt gtttcaactg tttttcaaaa tcctaagaca
     5041 tattttttta atgtcaatac gacattagaa ttattatttt atttggaaaa tatcggtctt
     5101 gcaagagaag agatggacag gcgtttgaag gatatgcttg agatattccc gataaaaaat
     5161 cttttgaaca gaaatatatt taatctatcc ggcggtgaaa aacaaattct ttgcattgca
     5221 gcttcttata tagcaggtac aaagattata gttatggatg agtcttcatc gaatttagat
     5281 attaaaagca taagtgtttt ggcaaagatg ctaaagatat taaaagagaa aggcataagc
     5341 ataattgttg cagagcatag aatttattat ttgatggaca tagttgaccg tgtattttta
     5401 atagataaag gaaagcttaa aaaaacttat actagaagtg aatttttaaa gctagataaa
     5461 aatgaattaa atgctttaag tttaagagat aaagaattaa gtaaattaaa agttccttat
     5521 ttaaaagaag gtggagagta tcagataaaa aatcttagct acaaatttac tgatgatgag
     5581 tgtttaagct taaaagatat ttcattcaag cttgggaaaa tttatggcat aataggatcc
     5641 aacggacgag gaaaatcaac gcttttaaga tgtttaatag gtcttgagaa aaaatcaaaa
     5701 gaagaaattt attttaaggg agagaagcta tctaaaaaag aaagactcaa aaactcttca
     5761 cttgttatgc aagatgtaaa tcatcaatta ttcacagatg aggtattcaa cgagcttaga
     5821 ttaggaataa agaattttga tgaagaaaag gcgaaaatca ttttaaaaga tttaggcctg
     5881 gacgaattta ttgaaaggca tccgatgagt ttatcaggag ggcaaaagca aaggcttgca
     5941 atagcatctg ttatgtgcaa gacttctcca tttatctttt ttgacgaacc ttcaagtggt
     6001 atggattatt ccaatatgat aaaaatatct gaactgatta ataagtataa aaccatggat
     6061 aaaataattt ttattgtttc ccatgatata gaatttttaa atgaagtggc agatgaaatt
     6121 tttgaa
//
LOCUS       DAVKXA010000076         5924 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKXA010000076 DAVKXA010000000
VERSION     DAVKXA010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5924
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.076"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            123..896
                     /locus_tag="VW883_001992"
     CDS             123..896
                     /locus_tag="VW883_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0275068.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYDWKIEKELNSIEVINLMGNHDVYYLLGEQVPFSIQNLEVFFSV
                     QQLLQDLNLQVAYQLDDYLVSHAGFNLLFDPKEWHFKPFTEEYEEELEILANAVGYMR
                     GGGDMAGSPLWAHFRELELIPNHNYPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYVQGHLEIFSTDWATDQTLKQLPKPQI"
     gene            1080..1862
                     /locus_tag="VW883_001993"
     CDS             1080..1862
                     /locus_tag="VW883_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEV0275069.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTDTKSKEKSQR
                     RTFDELTPEEQEQRLERMKKTRLEAKWNLLRLVDCNYNDNTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYLTVLEKQKRGAWHAHILLFSVPYVPHRQLLELW
                     GHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDRFY
                     TYEDFNYDSSVVLYETEYISKVYKDGQYFDNHVKYKKIKLDE"
     gene            1876..2079
                     /locus_tag="VW883_001994"
     CDS             1876..2079
                     /locus_tag="VW883_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV0275070.1"
                     /translation="MIATVTKNDLVALGFSEGTSKHIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLGFDVQNSTLKE"
     gene            2083..3215
                     /locus_tag="VW883_001995"
                     /pseudo
     CDS             2083..3215
                     /locus_tag="VW883_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            3256..3693
                     /locus_tag="VW883_001996"
     CDS             3256..3693
                     /locus_tag="VW883_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HEV0275071.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPEIVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            3909..4145
                     /locus_tag="VW883_001997"
     CDS             3909..4145
                     /locus_tag="VW883_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEV0275072.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWGECGKKAISHEEMMRRYG"
     gene            4138..4869
                     /locus_tag="VW883_001998"
     CDS             4138..4869
                     /locus_tag="VW883_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0275073.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(4980..5063)
                     /locus_tag="VW883_001999"
     tRNA            complement(4980..5063)
                     /locus_tag="VW883_001999"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5027..5029),aa:Leu,seq:caa)
     gene            complement(5073..5144)
                     /locus_tag="VW883_002000"
     tRNA            complement(5073..5144)
                     /locus_tag="VW883_002000"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5110..5112),aa:Gln,seq:ttg)
     gene            complement(5155..5227)
                     /locus_tag="VW883_002001"
     tRNA            complement(5155..5227)
                     /locus_tag="VW883_002001"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5192..5194),aa:His,seq:gtg)
     gene            complement(5242..5312)
                     /locus_tag="VW883_002002"
     tRNA            complement(5242..5312)
                     /locus_tag="VW883_002002"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5278..5280),aa:Trp,seq:cca)
     gene            complement(5317..5397)
                     /locus_tag="VW883_002003"
     tRNA            complement(5317..5397)
                     /locus_tag="VW883_002003"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5361..5363),aa:Tyr,seq:gta)
     gene            complement(5410..5482)
                     /locus_tag="VW883_002004"
     tRNA            complement(5410..5482)
                     /locus_tag="VW883_002004"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5447..5449),aa:Phe,seq:gaa)
     gene            complement(5486..5559)
                     /locus_tag="VW883_002005"
     tRNA            complement(5486..5559)
                     /locus_tag="VW883_002005"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5523..5525),aa:Met,seq:cat)
     gene            complement(5570..5659)
                     /locus_tag="VW883_002006"
     tRNA            complement(5570..5659)
                     /locus_tag="VW883_002006"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5621..5623),aa:Ser,seq:tga)
     gene            complement(5742..5815)
                     /locus_tag="VW883_002007"
     tRNA            complement(5742..5815)
                     /locus_tag="VW883_002007"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5779..5781),aa:Ile,seq:gat)
     gene            complement(5850..5920)
                     /locus_tag="VW883_002008"
     tRNA            complement(5850..5920)
                     /locus_tag="VW883_002008"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5886..5888),aa:Gly,seq:tcc)
BASE COUNT         2189 a         1043 c         1024 g         1668 t
ORIGIN      
        1 ttcatggaaa ttattaaata acatcttaag aataattaat tctatttatc tatcaccgaa
       61 acaatgtgct ataacttaat tcgattctta gactaatatc aaaaataaag aggggaatat
      121 atatgaagac gttattaatt ggtgatttac acttaaaatc tcaactgatt ttacccattg
      181 ttgacaaaat tatccaaaca cataatatta agagaatcat ttttcttggt gattatgttg
      241 atttacatgg acaaactaac aatatccaac tatatgccaa agacctcact tttctatacg
      301 attggaaaat agaaaaagaa ttaaattcaa tagaagttat taaccttatg ggcaatcacg
      361 atgtttatta tttacttgga gaacaagttc ctttctcaat tcaaaatcta gaggtctttt
      421 tctcagttca acaattatta caagatttga atttacaagt agcttatcaa ctagatgatt
      481 atttagttag ccatgctggt ttcaatttgc tatttgaccc aaaagaatgg cactttaaac
      541 cttttactga agaatatgaa gaagaattag aaatccttgc taatgcagta ggatatatgc
      601 gtggaggagg agatatggct ggttctcctt tatgggctca ttttagagaa ctagagctaa
      661 tccctaatca caactaccct aaacaaattg ttggacatac ccctaaagaa tctatcgata
      721 tttctaaaaa tgttattggt atagatactt tttcattata tattgacaaa gataataaat
      781 atcaatttat tggtaacgga gatttgctcg tttatgtcca aggacatctt gaaatctttt
      841 caactgactg ggctacagac caaacattaa aacaattacc taaacctcaa atttaactac
      901 tacttctcat catgtgacta agcgaaactg ccgactggaa gtcggcaagc tggaagcgtg
      961 tttagcagag cgatgcttag aaacacatga tagaagtatg gaggagcttt gcttctccta
     1021 gtttatttat tatatagaca atcttttggc gaaagccaac ctaaaaggaa ctatttttta
     1081 tgacctcgta taataaaaaa atagtccgca cttcttccta tattgaaatt tgggaatatg
     1141 aaaaaccaat attttcaaaa ggaaaatcca ttttagatac tgatactaaa agcaaggaaa
     1201 aatcacaacg tagaacattt gatgaactta cacctgaaga acaagaacaa cgtctggagc
     1261 gtatgaaaaa aactcgctta gaagcaaagt ggaacttact tcgattagtt gattgtaatt
     1321 ataatgataa tacttcattt ctaaccctga ccactaaaga aaatattagc gacagaaacc
     1381 acttcaaaga cttactaaaa acttttataa aacgctttaa ctaccacatc tttaatacca
     1441 agaaaagtaa attaaaatat ttaacagtat tagaaaagca aaaacgtgga gcatggcatg
     1501 ctcatattct gcttttcagc gttccttatg taccacaccg tcaactcttg gaactttggg
     1561 gacatggagc agtacggata aataaagttg atgtagacag caaagaaaat cgcggtcgat
     1621 atgtcacaaa gtattttgaa aaagggattg gacaagaatt gttggaaaac ttcggaaagc
     1681 aagcctattt ttcatcacgc aacttaaaaa agcctgatga agatagattt tatacttatg
     1741 aagattttaa ttatgatagt tcagtcgtac tatatgaaac ggaatacatt agtaaagtct
     1801 ataaagacgg tcagtatttc gataatcatg taaagtataa gaaaataaaa ctagatgaat
     1861 aaaggagtaa gttacatgat agcaactgtt actaagaatg acctagttgc ccttggtttt
     1921 tctgagggca catctaaaca tattatccgc caagggaaag agctactgat aacccgaggc
     1981 tttacagtct atcagaacaa gcgaattggt actatacctg ctactattgc taccgaatta
     2041 ctcggttttg atgttcaaaa cagtaccctc aaggagtaaa atatggcaat tagaaaaggt
     2101 aaagacggta attgggtagt tgatattagc aacggttttg acccaataac actaaagcaa
     2161 cgtagacttg tcagaaaggg atatatgacg aaaaaagaag ctattgaagc agaacactac
     2221 ttacgaagtg tagagttaaa agaacgcttc tatggggcta aaataactat ctccatacta
     2281 tatgaactac ttaaggaaga agatagcata aatcatcgaa aagcaagcta tatcaataca
     2341 caagataata attacaacaa acacatcaaa gattattttt ctatggtcga taatgtcgga
     2401 aactaaccta tgaagacatc taccaattta gagaacatct taggcaaaaa gtagctaaaa
     2461 attctgataa accgttaagc acaaatacta ttaacaaaat catgatttta ctcaaaaaaa
     2521 tttttgatgt tggtttgcga aaaggctatt actcctccaa tccagcaaaa ttgataaaaa
     2581 agttgccaat tgaaaaaaca aaaatgcaat tttggacagt caaagaattt cagaagtttt
     2641 tgacactatt tgaacccgaa gaatacaata tcaaactact ctttactgtt ctattcttta
     2701 caggattaag acttggggaa gctcttgccc taacatggca agacatcgac ttttcaagta
     2761 atacaattca tatcacgaaa tctgtctatg ttaataaagg agtaactcat atcagcacaa
     2821 caaaaactaa agcaggaaca agaagaattg ttatcaataa aaaattaagc caagaattac
     2881 aagattggga aaagcgacaa aaacatctat tagagcaatt taccaacaat agcctaacat
     2941 tacaagtgtt tcaaaatagt cctatcacaa ttacgaaaaa tgctattgaa aagcagtaca
     3001 agaaaatcat tgaacgtgat agcacactaa aaaagatacg catacacgat tttaggcact
     3061 cacacgcttc cctgctgatt aaccaagggg aagattatct agttgtaaaa gagcgactag
     3121 gacatgcttc tataacaacc acgattgata cctactctca cttgtaccca agtaagcaaa
     3181 aggatttagc tgataaacta gatgatttac tataaagtaa ttgagtttta taaatggaaa
     3241 gtttataatt aaatcatgga tacatcacaa gtaataaaag cacatgaagt agctaaaaaa
     3301 gcacactttg gacaaattga tagagcagga attgactaca ttaaacaccc tgaaatagta
     3361 gctagttttg tcgcaactga tgaagagaaa gctgtcgcct atctacatga tgtaattgaa
     3421 gatacttcac taaccctact agacctaaaa aaggaaggtt tttcaaaaaa cattatagaa
     3481 gccgtcgata tactcacaaa gaaaaaagga caagattatc aatcctatct caatctagta
     3541 aagaaaaatg aactcgctag agttgtaaaa ttggcggatt tacggcataa ttcagattta
     3601 acaagactac cattaattac tgaaaaagac ttagagagaa ataagaaata cagttctgct
     3661 attagatttt taagagcaaa gaaaaaaagt tagtaactaa actataaaat tttataaaga
     3721 gaaaataaaa gacaaggctt ataaactttg tctttattac tatactggcg gtcggtctcg
     3781 aactggcaca tccttgcaga tactacaatt ttattaaaat aaataactat aaaaagtgaa
     3841 attttttatt gagaaacttt tagactagga gtataatgta tctaaaataa ctattaggtg
     3901 gctgttatat gaataatgtt gttactacac aaatttctat tcaacttagt caagagttaa
     3961 attctttatt aaatgctatt gttgaagaaa ataatacaac aaagactgac tttattagac
     4021 aagctgttat agagaaaatt gaagatatgt atgatattaa ggtcgctgat gaagcttata
     4081 aaaaatgggg tgaatgtggc aaaaaagcta tctcacatga agaaatgatg agacgctatg
     4141 gctaaattat acgcaatatc tgatatacat ggatacttgg atgaattcag agacgctctc
     4201 aataaagtaa atttaaacga taaagataat cgcctatttt tactaggaga ttatcttgat
     4261 aatggacttc aatcttttca agtcatttcc aaaataatcg aacttgagga ggtttatcct
     4321 aatcaaatta ttactcttct agggaatcat gaagaatggt tttatgattg gttgatttta
     4381 gataaaccta ctgcttcagc atttccagaa acaataaaaa gcttcttctc tccagaggaa
     4441 ttaaactata tttttaaatc gaatgctaac aactttgaaa caggtgttag aaatgaaatt
     4501 aaaaataata tcaaattcaa cccatttata aactggttta aaaagcgata tagggataaa
     4561 cgctattatg aaactgatac ccaaattttt gttcatgcag gcattgatga agaagcagga
     4621 atgctttgga aagaactaac gagttcaaag atatttacaa acaaatttcc aattaccact
     4681 ggtagatttc ataaagctat tatttcgggc catattgctt cttgggaagt agctaaagat
     4741 agaagatacc taggtaagat ttactatgat agtaaaagtc attacttaat tgatggagat
     4801 gtaacgaata gcaaaacaat acctgttctt tgctatgata caattaccca aaaatatcac
     4861 tttctataac ttttagtcat gtgcttttat atgaaattag taattattag taacaattcc
     4921 aagaaatttc ttatgacata acaaaaagac aaggcttata aaccttgtct tctaaactat
     4981 accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga gtccagcgcg
     5041 tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg aaccaacgca
     5101 tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaatataa aataggcgag
     5161 tgatggggat cgaacccacg catgccagag ccacaatctg gtgtgttaac cacttcacca
     5221 cacccgccat aattctatta acacgggcag taggaattga acccacactg aaggttttgg
     5281 agaccttagt tctaccttta aactatgccc gtaaaatgga aggggaggga ttcgaacccc
     5341 cgaacccgaa ggagcggatt tacagtccgc cgcgtttagc ctcttcgcta cccttccaaa
     5401 atatataaat ggcgcgagac ggaatcgaac cgccgacaca tggagcttca atccattgct
     5461 ctaccaactg agctaccgag ccttattgcg ggagcaggat ttgaacctac gaccttcggg
     5521 ttatgagccc gacgagctac cgagctgctc catcccgcgt taatataaaa ggaggatgtg
     5581 ggattcgaac ccacgcacgc ttttacacgc ctgacggttt tcaagaccgt tcccttcagc
     5641 cggacttggg taatcctcca aaatagttta tacgggaaca agcccgtgtc ctcttagtga
     5701 acagataata ttccaattcc ttagtaatgg actaaacact atgggcacga gtggactcga
     5761 accaccgacc tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtc
     5821 aaaaacttgg tacaaagaac aaagttcaaa gcgggtgacg agaatcgaac tcgcgacaac
     5881 agcttggaag gctgtagttt taccactaaa ctacacccgc taaa
//
LOCUS       DAVKXA010000077         5831 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKXA010000077 DAVKXA010000000
VERSION     DAVKXA010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.077"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            27..293
                     /locus_tag="VW883_002009"
     CDS             27..293
                     /locus_tag="VW883_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0275074.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            286..654
                     /locus_tag="VW883_002010"
     CDS             286..654
                     /locus_tag="VW883_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0275075.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            774..2042
                     /locus_tag="VW883_002011"
     CDS             774..2042
                     /locus_tag="VW883_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0275076.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMAYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            2039..3316
                     /gene="tilS"
                     /locus_tag="VW883_002012"
     CDS             2039..3316
                     /gene="tilS"
                     /locus_tag="VW883_002012"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0275077.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLTLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETAIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            3320..3862
                     /gene="hpt"
                     /locus_tag="VW883_002013"
     CDS             3320..3862
                     /gene="hpt"
                     /locus_tag="VW883_002013"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0275078.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            3878..>5831
                     /gene="ftsH"
                     /locus_tag="VW883_002014"
     CDS             3878..>5831
                     /gene="ftsH"
                     /locus_tag="VW883_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0275079.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         2034 a          871 c         1193 g         1733 t
ORIGIN      
        1 tacaataata aattgaggta ataaggatga gattagataa atatttaaaa gtatcgcgaa
       61 ttatcaagcg tcgtacagtc gcaaaggaag tagcagataa aggtagaatc aaggttaatg
      121 gaatcttggc caaaagttca acggacttga aagttaatga ccaagttgaa attcgctttg
      181 gcaataagtt gctgcttgta aaagtactag agatgaaaga tagtacaaaa aaagaagatg
      241 cagcaggaat gtatgaaatt atcagtgaaa cacgggtaga agaaaatgtc taaaaatatt
      301 gtacaattga ataattcttt tattcaaaat gaataccaac gtcgtcgcta cctgatgaaa
      361 gaacgacaaa aacggaatcg ttttatggga ggggtattga ttttgattat gctattattt
      421 atcttgccaa cttttaattt agcgcagagt tatcagcaat tactccaaag acgtcagcaa
      481 ttagcagact tgcaaactca gtatcaaact ttgagtgatg aaaaggataa ggagacagca
      541 tttgctacca agttgaaaga tgaagattat gctgctaaat atacacgagc gaagtactat
      601 tattctaagt cgagggaaaa agtttatacg attcctgact tgcttcaaag gtgataaaat
      661 ggaaaattta ttagacgtaa tagagcaatt tttgagtttg tcagatgaaa agctggaaga
      721 attggctgat aaaaatcaat tattgcgttt acaagaagaa aaggaaagga agaatgcgta
      781 aattcttaat tattttgttg ctaccaagtt ttttgaccat ttcaaaagtc gttagcacag
      841 aaaaagaagt cgtctatact tcgaaagaaa tttattacct ttcacaatct gactttggta
      901 tttattttag agaaaaatta agttctccca tggcttatgg agaggttcct gtttatgcga
      961 atgaagattt agtagtggaa tctgggaaat tgactcccaa aacaagtttt caaataaccg
     1021 agtggcgctt aaataaacaa ggaattccag tatttaagct atcaaatcat caatttatag
     1081 ctgcggacaa acgattttta tatgatcaat cagaggtaac tccaacaata aaaaaagtat
     1141 ggttagaatc tgactttaaa ctgtacaata gtccttatga tttaaaagaa gtgaaatcat
     1201 ccttatcagc ttattcgcaa gtatcaatcg acaagaccat gtttgtagaa ggaagagaat
     1261 ttctacatat tgatcaggct ggatgggtag ctaaagaatc aacttctgaa gaagataatc
     1321 ggatgagtaa agttcaagaa atgttatctg aaaaatatca gaaagattct ttctctattt
     1381 atgttaagca actgactact ggaaaagaag ctggtatcaa tcaagatgaa aagatgtatg
     1441 cagccagcgt tttgaaactc tcctatctct attatacgca agaaaaaata aatgagggtc
     1501 tttatcagtt agatacgact gtaaaatacg tatctgcagt caatgatttt ccaggttctt
     1561 ataaaccaga gggaagtggt agtcttccta aaaaagaaga taataaagaa tattctttaa
     1621 aggatttaat tacgaaagta tcaaaagaat ctgataatgt agctcataat ctattgggat
     1681 attacatttc aaaccaatct gatgccacat tcaaatccaa aatgtctgcc attatgggag
     1741 atgattggga tccaaaagaa aaattgattt cttctaagat ggccgggaag tttatggaag
     1801 ctatttataa tcaaaatgga tttgtgctag agtctttgac taaaacagat tttgatagtc
     1861 agcgaattgc caaaggtgtt tctgttaaag tagctcataa aattggagat gcggatgaat
     1921 ttaagcatga tacgggtgtt gtctatgcag attctccatt tattctttct attttcacta
     1981 agaattctga ttatgatacg atttctaaga tagccaagga tgtttatgag gttctaaaat
     2041 gagggaacca gattttttaa atcattttct caagaaggga tatttcaaaa agcatgctaa
     2101 ggcggttcta gctctttctg gtggattaga ttctatgttt ctatttaagg tattgtctac
     2161 ttatcaaaaa gagttagaga ttgaattgat tctggctcat gtgaatcata agcagagaat
     2221 tgaatcagat tgggaagaaa aggaattaag gaagttggct gctgaagcag agcttcctat
     2281 ttatatcagc aatttttcag gagaattttc agaagcgcgt gcacgaaatt ttcgttatga
     2341 tttttttcaa gaggttatga aaaagacagg tgcgacagct ttagtcactg cccaccatgc
     2401 tgatgatcag gtggaaacga ttttgatgcg cttgattcga ggaactcgct tgcgctatct
     2461 atcaggaatt aaggagaagc aagtagtcgg agagatagaa atcattcgtc ccttcttgca
     2521 ttttcagaaa aaagactttc catcaatttt tcactttgaa gatacatcaa atcaggagaa
     2581 tcattatttt cgaaatcgta ttcgaaactc ttacttacca gaattggaaa aagaaaatcc
     2641 tcgatttagg gatgcaatct taggcattgg caatgaaatt ttagattatg atttggcaat
     2701 agctgaatta tctaacaata ttaatgtgga agatttacag cagttatttt cttactctga
     2761 gtctacacaa agagttttac ttcaaactta tctgaatcgt tttccagatt tgactcttac
     2821 aaaagctcag tttgctgaag ttcagcagat tttaaaatct aaaagccagt atcgtcatcc
     2881 gattaaaaat ggctatgaat tgataaaaga gtaccaacag tttcagattt gtaaaatcag
     2941 tccgcaggct gatgaaaagg aagatgaact tgtgttacac tatcaaaatc aggtagctta
     3001 tcaaggatat ttattttcct ttggacttcc attagaaggt gaatcaattc aacaaatacc
     3061 tgtttcacgt gaaacagcca tacacattcg tcatcgaaaa acaggagatg ttttgattca
     3121 aaatgggcat agaaaaaaac tcagacgttt atttattgat ttgaaaatcc ctatggaaaa
     3181 gagaaactct gctcttatta ttgagcaatt tggtgaaatt gtctcaattt tgggaattgc
     3241 gaccaataat ttgagtaaaa aaacgaaaaa tgatataatg aacactgtac tttatataga
     3301 aaaaatagat aggtaaaaaa tgttagaaaa cgatattaaa aaagtcctcg tttcacacga
     3361 tgaaattaca gaagcagcta aaaaactagg tgctcaatta actaaagatt atgcaggaaa
     3421 aaatccaatc ttagttggga ttttaaaagg atctattcct tttatggctg aattggtcaa
     3481 acatattgat acacatattg aaatggactt catgatggtt tctagctacc atggtggaac
     3541 agcaagtagt ggtgttatca atattaaaca agatgtgact caagatatca aaggaagaca
     3601 tgttctattt gtagaagata tcattgatac aggtcaaact ttgaagaatt tgcgagatat
     3661 gtttaaagca agagaagcag cttctgttaa aattgcaacc ttgttggata aaccagaagg
     3721 acgtgttgta gaaattgagg cagactatac ctgctttact atcccaaatg agtttgtagt
     3781 aggttatggt ttagactaca aagaaaatta tcgtaatctt ccttatattg gagtattgaa
     3841 agaggaagtg tattcaaatt agaaagaata atctttaatg aaaaaacaaa ataatggttt
     3901 aattaaaaat ccttttctat ggttattatt tatctttttc cttgtgacag gattccagta
     3961 tttctattct gggaataact caggaggaag tcagcaaatc aactatactg agttggtaca
     4021 agaaattacc gatggtaatg taaaagaatt aacttaccaa ccaaatggta gtgttatcga
     4081 agtttctggt gtctataaaa atcctaaaac aagtaaagaa ggaacaggta ttcagttttt
     4141 cacgccatct gttactaagg tagagaaatt taccagcact attcttcctg cagatactac
     4201 cgtatcagaa ttgcaaaaac ttgctactga ccataaagca gaagtaactg ttaagcatga
     4261 aagttcaagt ggtatatgga ttaatctact cgtatccatt gtgccatttg gaattctatt
     4321 cttcttccta ttctctatga tgggaaatat gggaggaggc aatggccgta atccaatgag
     4381 ttttggacgt agtaaggcta aagcagcaaa taaagaagat attaaagtaa gattttcaga
     4441 tgttgctgga gctgaggaag aaaaacaaga actagttgaa gttgttgagt tcttaaaaga
     4501 tccaaaacga ttcacaaaac ttggagcccg tattccagca ggtgttcttt tggagggacc
     4561 tccggggaca ggtaagactt tgcttgctaa ggcagtcgct ggagaagcag gtgttccatt
     4621 ctttagtatc tcaggttctg actttgtaga aatgtttgtc ggagttggag ctagtcgtgt
     4681 tcgctctctt tttgaggatg ccaaaaaagc agcaccagct atcatcttta tcgatgaaat
     4741 tgatgctgtt ggacgtcaac gtggagtcgg tctcggcgga ggtaatgacg aacgtgaaca
     4801 aaccttgaac caacttttga ttgagatgga tggttttgag ggaaatgaag ggattatcgt
     4861 catcgctgcg acaaaccgtt cagatgtact tgatcctgcc cttttgcgtc caggacgttt
     4921 tgatagaaaa gtattggttg gccgtcctga tgttaaaggt cgtgaagcaa tcttgaaagt
     4981 tcacgctaag aacaagcctt tagcagaaga tgttgatttg aaattagtgg ctcaacaaac
     5041 tccaggcttt gttggtgctg atttagaaaa tgtcttgaat gaagcagctt tagttgctgc
     5101 tcgtcgcaat aaatcgataa ttgatgcttc agatattgat gaagcagaag atagagttat
     5161 tgctggacct tctaagaaag ataagacagt ttcacaaaaa gaacgagaat tggttgctta
     5221 ccatgaggca ggacatacca ttgttggtct agtcttgtcg aatgctcgcg ttgtccataa
     5281 ggttacaatt gtaccacgcg gccgtgcagg cggatacatg attgcacttc ctaaagagga
     5341 tcaaatgctt ctatctaaag aagatatgaa agagcaattg gctggcttaa tgggtggacg
     5401 tgtagctgaa gaaattatct ttaatgtcca aactacagga gcttcaaacg actttgaaca
     5461 agcgacacaa atggcacgtg caatggttac agagtacggt atgagtgaaa aacttggccc
     5521 agtacaatat gaaggaaacc atgctatgct tggtgcacag agtcctcaaa aatcaatttc
     5581 agaacaaaca gcttatgaaa ttgatgaaga ggttcgttca ttattaaatg aggcacgaaa
     5641 taaagctgct gaaattattc agtcaaatcg tgaaactcac aagttaattg cagaagcatt
     5701 attgaaatac gaaacattgg atagtacaca aattaaagct ctttacgaaa caggaaagat
     5761 gcctgaagca gtagaagagg aatctcatgc actatcctat gatgaagtaa agtcaaaaat
     5821 gaatgacgaa a
//
LOCUS       DAVKXA010000078         5581 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKXA010000078 DAVKXA010000000
VERSION     DAVKXA010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.078"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1273..2532
                     /locus_tag="VW883_002015"
     CDS             1273..2532
                     /locus_tag="VW883_002015"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0275080.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAKGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2548..3099
                     /locus_tag="VW883_002016"
     CDS             2548..3099
                     /locus_tag="VW883_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0275081.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            3092..4369
                     /locus_tag="VW883_002017"
     CDS             3092..4369
                     /locus_tag="VW883_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0275082.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQIHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4385..5245
                     /locus_tag="VW883_002018"
     CDS             4385..5245
                     /locus_tag="VW883_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0275083.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         1682 a          906 c         1258 g         1735 t
ORIGIN      
        1 gcgtcgtagt ccagcttagc gatgatttct ttgtgtgaat ccctattgac gacatctata
       61 atttggatat ttgtgtcttt gatatcgagt agttttgtga taaaatgtaa ttgtcccaca
      121 tgaatctttc taatgagttg tttgatcgct tttcattata gatcttatgg gacttttttt
      181 ctacaataaa ataggctcca taatatctat agtggattta cccactacaa atattataga
      241 gccaaaaatc ccgtgcctca tcagacacgg gattttgtgg tacgacaggc atgtatagca
      301 aactgaatct ggaatagcac agcatatctt ctaaaatatt gttataaatt gatttgaatt
      361 tcaaaattaa attgtttgat tcttatttca atttgttata gtatatctga tgtcaaagtt
      421 ctcggcgagt caaatagcga ttcccaagcc tgactatcgt gaggtagcgg attaaaatgg
      481 tctggggata gaccgtttta agtctgacgc tggaaataag aattgtcaga agaagggata
      541 gcgaaatcgt ggctctacga acaggaacgt gataataagg cgtatatagc ggataagagg
      601 gcatcaaact ctaaagtcca aaaaggtagt cgtaacctat atgcgtaaat cacgagagta
      661 attgaattcg tactaagatt ttctattttc actgtaacct tttaacgccc ttatatcttg
      721 tatacacgag gaaagatgta cgacttatcc cgtgaggtct atcactataa agagaaaacg
      781 acagatagaa gtgatcctga gtcacggtta tctgtctgat aggacggtat gtataaaacg
      841 cttctgtgaa ctgagagaag ggggagaagt tcttgctaaa atttagttga acagccgtat
      901 tccgatactt agataagaga tctagtctta gctcctactc agttttaggg gataaaaaag
      961 gggcaatagc gattcgagaa agattatact cttcgaaaat ctcttcaaat cacgtcaata
     1021 tcgccttgtc gtatgtgtag gatactgact acgtcagttc catctacaac ctcaaaacag
     1081 tgttttgagc aacctgcggc tagtttccta gtttgatctt tgattttcat tgagtattag
     1141 taattcagtt actaactcgt caactctgat ttatccaata aaattgaaaa ggatggaaaa
     1201 aaggataaat ttatgatata ctttattttg aagaccttat tagaaatctt gaaagagtat
     1261 tgaaaactta gaatgagaaa aattgttatc aatggtggat taccactgca aggtgaaatc
     1321 actattagtg gtgctaaaaa tagtgtcgtt gccttaattc cagctattat cttggctgat
     1381 gatgtggtga ctttggattg cgttccagat atttcggatg tagccagtct tgtcgaaatc
     1441 atggaattga tgggagctac tgttaagcgt tatgacgatg tattggagat tgacccaaga
     1501 ggtgttcaaa atattccaat gccttatggt aaaattaaca gtcttcgtgc atcttactat
     1561 ttttatggga gcctcttagg ccgttttggt gaagcgacag ttggtctacc gggaggatgt
     1621 gatcttggtc ctcgtccgat tgacttacac cttaaggcgt ttgaagctat gggtgccact
     1681 gctagctacg agggagataa catgaagtta tctgctaaag atacaggact tcatggtgca
     1741 agtatttaca tggatacggt tagtgtggga gcaacgatta atacgatgat tgctgcggtt
     1801 aaagcaaatg gtcgtactat tattgaaaat gcagcccgtg aacctgagat tattgatgta
     1861 gctactctct tgaataatat gggtgcccat atccgtgggg caggaactaa tatcatcatt
     1921 attgatggtg ttgaaagatt acatgggaca cgtcatcagg tgattccaga ccgcattgaa
     1981 gctggaacat atatatcttt agctgctgca gttggtaaag gaattcgtat aaataatgtt
     2041 ctttacgaac acctggaagg gtttattgct aagttggaag aaatgggagt gagaatgact
     2101 gtatctgaag acagcatttt tgtcgaggaa cagtctaatt tgaaagcaat caatattaag
     2161 acagctcctt acccaggctt tgcaactgat ttgcaacaac cgcttacccc tcttttacta
     2221 agagcgaatg gtcgtggtac aattgtcgat acgatttacg aaaaacgtgt aaatcatgtt
     2281 tttgaactag caaagatgga tgcggatatt tcgacaacaa atggtcatat tttgtacacg
     2341 ggtggacgtg atttacgtgg ggccagtgtt aaagcgaccg acttaagagc tggggctgca
     2401 ctagtcattg ctgggcttat ggctaaaggt aaaactgaaa ttaccaatat cgagtttatc
     2461 ttacgtggtt attctgatat tatcgaaaaa ttacgtaatt taggagcgga tattagactt
     2521 gttgaggatt aaaccgtaga ggtgtttatg aatatttgga ccaaattagc aatgttttct
     2581 ttttttgaaa cggatcgctt gtatttgcgt cctttctttt ttagtgatag tcaggacttc
     2641 cgcgagatag cttcaaatcc agaaaatctt caatttattt tcccaacgca ggcaagtctg
     2701 gaagaaagtc aatatgcact ggccaattac tttatgaagt cccctttggg agtgtgggca
     2761 atttgtgacc agaaaaatca acaaatgatt ggttctatta aatttgagaa gttagatgaa
     2821 atcaaaaaag aagctgagct tggctatttt ttgagaaaag atgcttggtc gcaaggattt
     2881 atgacagagg ttgttagaaa aatttgtcag ctttcttttg aggaatttgg cttaaaacaa
     2941 ttatttatca ttacccacct tgaaaataaa gctagccaaa gagttgctct taagtctgga
     3001 tttagtttgt tccgtcagtt taagggaagt gatcgttaca caagaaaaat gcgggattat
     3061 cttgaatttc ggtatgtaaa aggagagttc aatgagtaag catcaggaaa ttctaagcta
     3121 tttggaggaa ttaccagtag gtaaaagggt cagtgttcgt agcatttcga atcatctagg
     3181 agttagtgat ggaacagcct atcgggctat taaagaagct gaaaaccgtg gaattgtgga
     3241 gacccgtcct agaagtggaa caattcgtgt taaatcccag aaagttgcta tagagagatt
     3301 aacgtttgct gaaattgcag aagtgacttc ttctgaggtt ctggctgggc aagaaggttt
     3361 agagagagaa tttagtaagt tttcaattgg tgccatgact gaacaaaata tcttgtctta
     3421 ccttcatgat ggggggctct tgattgtcgg agaccgaacc cgtattcagt tgctagcctt
     3481 ggaaaatgaa aatgcagttc tggttacagg gggatttcag attcatgatg atgtgcttaa
     3541 actggccaat caaaaaggga ttcctgttct aagaagtaag catgatacct ttaccgtcgc
     3601 gaccatgatc aataaagcct tgtcaaatgt ccaaatcaag actgatattc tgacagttga
     3661 gaaactttat cgccctagtc atgagtatgg ttttctgaga gagacagata cagttaaaga
     3721 ttatttggac ttggttcgta agaatcgtag cagccgtttc cctgttatca atcaacatca
     3781 ggtcgttgtt ggtgttgtaa ccatgagaga cgctggtgat aaatcaccaa gcacgacaat
     3841 tgataaggtt atgtctcgta gtctattttt ggttggatta tcgacaaata ttgccaatgt
     3901 gagtcaacgg atgatcgcag aagactttga aatggtacca gttgttcgaa gcaatcaaac
     3961 tttgcttggc gttgtgacgc gacgagatgt catggagaag atgagccgtt cccaagtttc
     4021 ggctctacca actttttctg agcagattgg acaaaagctc tcttatcacc atgatgaagt
     4081 agtcattaca gtggaaccct ttatgctaga aaaaaatgga gttttggcta atggtgtatt
     4141 ggcagaaatt ctgacccaca tgacccaaga tttagttgtt aatagtggtc gcaatctcat
     4201 tatcgagcag atgctgatct actttttgca ggctgttcag atagatgata tattgcgcat
     4261 tcaggcacgg attattcatc atacgagacg gtcagctata attgattacg atatttatca
     4321 tggtcaccag attgtttcaa aagcaaatgt gactgttaaa attaattaga aactaggaga
     4381 aaagatgata acattaaaat cagctcgtga aatcgaagct atggacaagg ctggtgattt
     4441 tctagcaagt attcatatag gcttacgtga tttgattaag ccaggcgtag atatgtggga
     4501 agttgaagaa tatgtccgcc gtcgttgtaa agaagaaaat ttccttccac ttcagattgg
     4561 ggttgacggt gccatgatgg actatcctta tgctacctgt tgctctctta acgatgaagt
     4621 ggctcacgct ttccctcgtc attatatctt gaaagatggt gatttgctca aagttgatat
     4681 ggttttggga ggtcccattg ctaaatctga cctgaatgtc tcaaaattaa acttcaacaa
     4741 tgttgaacaa atgaaaaaat acactcagag ctattctggt ggtttagcag actcatgttg
     4801 ggcttatgct gttggtacac cgtccgaaga agtcaaaaac ttgatggatg taaccaaaga
     4861 agctatgtac aagggtattg agcaagctgt tgttggaaat cgtatcggtg atatcggtgc
     4921 ggctattcaa gaatacgctg aaagtcgtgg ttacggtgta gtgcgtgatt tggttggtca
     4981 tggtgttggc ccaactatgc acgaagaacc aatggttcct aattatggta ttgcaggtcg
     5041 tggactccgt cttcgtgaag gaatggtctt aaccattgaa ccaatgatca atacaggcga
     5101 ttgggaaatt gatacagata tgaaaactgg ttgggcgcat aagaccattg acggtggatt
     5161 gtcatgtcag tatgaacacc aatttgtcat tacgaaagat ggacctgtta tcttgactag
     5221 ccaaggtgaa gaaggaactt attaataaaa agtgaaaaga ctactggaag tttattttga
     5281 taaaaaatcc agtagatctt ttcataataa aacgcattgt atcaagtgtt aggggctgat
     5341 atcatgcgtt tttctgcttt ttagattttt tccaactctg tttgtaagcg catcataaca
     5401 aagggtctag gattcagggc tctcctccta tatactatta gtaaagtaaa actaagggag
     5461 gatattttag tgtcgcagtc tattgttcct gtagagattc cacaatattg tcgttttgat
     5521 tctaaaaaga gaaatggaat tctgtttaat gttcgtattg ccaatcttaa atttactttt
     5581 t
//
LOCUS       DAVKXA010000079         5495 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKXA010000079 DAVKXA010000000
VERSION     DAVKXA010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.079"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(128..1138)
                     /gene="ccpA"
                     /locus_tag="VW883_002019"
     CDS             complement(128..1138)
                     /gene="ccpA"
                     /locus_tag="VW883_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0275084.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1563..2162)
                     /locus_tag="VW883_002020"
     CDS             complement(1563..2162)
                     /locus_tag="VW883_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0275085.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2164..3261)
                     /locus_tag="VW883_002021"
     CDS             complement(2164..3261)
                     /locus_tag="VW883_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0275086.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(3261..3998)
                     /locus_tag="VW883_002022"
     CDS             complement(3261..3998)
                     /locus_tag="VW883_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0275087.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLHHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(4000..4884)
                     /locus_tag="VW883_002023"
     CDS             complement(4000..4884)
                     /locus_tag="VW883_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0275088.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(4871..5065)
                     /locus_tag="VW883_002024"
     CDS             complement(4871..5065)
                     /locus_tag="VW883_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275089.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(5062..5268)
                     /locus_tag="VW883_002025"
     CDS             complement(5062..5268)
                     /locus_tag="VW883_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275090.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1725 a         1237 c          921 g         1612 t
ORIGIN      
        1 caacctcaaa acagtgtgtt gcgcagcctt taaccagccg cctagtccgc tctatggtat
       61 tcattaagtc aacatctctt gtttaagagc acaaaatcag gaaatcttct cgattccctg
      121 attttttcta tttacgtttt cgtgttgagc tacgttctgt caaaccatga ggtaagagaa
      181 cttcacgttc ttccaactct tccttatgca taatcttggt caacatacgc atactaatgg
      241 caccaaggtc ataaagaggt tgggcaatcg ttgtcaagtt tggacgggta aagcgtgaga
      301 tttgtgaatc atcactagta ataatttcaa aatcttctgg cacagaaaca cccttatcag
      361 ccaaaccgtt caagactcct gctgccaact catcacctgt cacaactgct gcagttgcat
      421 ttgatgaaat caaacgctct gctaaggcgt aaccatcatc atagctatat ttagattcaa
      481 ataccaaacc ctcactataa gcgattcctg cttttttcaa ggtttccttg tagccaacta
      541 aacgaacctt accattgatg tcatccacta gcggaccgct aacgaaagca atacgctcat
      601 tttctttagc aaggtaactc actgcatcaa ttgttgcttg cttatagtca atattgacac
      661 ttggcaactg gtgctcaaca tcgacagttc ctgcgagaac aatcggagta cgtgaacgcg
      721 aaaattctga gcgaatttta tctgtcaagt gataacccat atagataatg ccatctacct
      781 gctttgaaaa gagggtattg acaacagaaa cttctttctc gttatcttca tcgctattag
      841 ctaggacaat attgtacttg tacatttctg caatatcatc aatcccctta gccaaactcg
      901 aaaaataacc attggtaata tttggaatca cgacaccgac agtggttgtc tttttacttg
      961 caagaccacg cgcaactgca tttggacgat aatccaaacg atcaattacc tctagcactt
     1021 ttttacgggt attctctttt acatttttat tgccattgac cacacggctg accgtcgcca
     1081 tggaaacacc tgcttcacga gcgacatcat aaatggttac tgtatcatct gcattcattc
     1141 cttttcctgt cctttctatc tcacacattc ttttacaagt agaggtactg attgaagctc
     1201 tatatctact tacaaaagtg aagatgtgaa aatttcgttt tcatatttct acttattcca
     1261 ttctatcact aattgtaaac actttcaagt gttttttgaa gattgattga aaaaatttca
     1321 tagaaaacct aggtttagct ccttgctacc accttagact aaacacaaag gaggaaacta
     1381 agccctccta aagttatagt aaaatgaaat aagaacagga taaatcgatc aggacagtca
     1441 aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctactat
     1501 aggtattgtt ccattcacta ccgtcaattt tagcacatag ccttcataaa aatattatat
     1561 catcataacc aaccagattc ttttgcgata ttagctgcct ctgttcgatt accagcatcc
     1621 agttttgaaa gaatattggt gacatagttt cgaatagttc cgtttgagag gtaaagctga
     1681 tctgcgattt cttggttgga taagccccgg gcgattccct ttaagacagc aatctcttgt
     1741 tctgtcaacg gattgggacg ggtcatcacc acttccatca attcaggcga atactccttg
     1801 cgtccttcga ggacggtgtg caaggtttgc atgaggtctg caatgcttcg ttcctttaat
     1861 acataagcat ccactccagc cttgaccgca cgttcaaaat acccagcacg cttgaaggtc
     1921 gtcaccacaa ccacctttgt ttcaagcctt tctgatcgta tccactccaa gacttcaaga
     1981 cctgtcttaa caggcatttc tacgtcaagg atggcgatat ctacagactc cttttctaat
     2041 agttggattg cttcttgccc attcttggct tgaaggacag actccacatc tggttgaagc
     2101 gtgagcaatt gacacatggc atctcgcaac atactttgat cttctgcgac taatactttc
     2161 atcttagttt ctctccttat aaggtagtcg aacttgcact tccgttggat gtttctgact
     2221 gattacactt acttctcctg aaaatggaaa aacacgatct cggactgtat ggagctcatc
     2281 tccttttaga aaagcaaagc cgcagccatc atcacttact gttaaaatga gttccttctc
     2341 tgtccgttct aattttaagt aagctttaga cgctttggca tgtttgatga tattggtcac
     2401 caactcaagc aaaatcatag aagccattga ctccaattct tgagtaaggc tagcagtatc
     2461 tagttggtta tccgtttcca cctcaattcc agcaatttct aacatctttt tcacagtctc
     2521 tagttcggat gtcaaagttc tagacttaag attttccaca atggttcgaa cttcacgcat
     2581 tgattctttg ctaatttgct gtatttctct taattccttt tccacttgtg gataagcctg
     2641 catttgaaat agctgcaagg ctagatctgt cttgacacta agcatagcaa aggtatgtcc
     2701 cagactatca tgcaaatcct gaccgatacg attgcgctca ttttctgcta gcaatagatt
     2761 tatctgggta ttttgcttga cctgagcttc tttcaaatcc tcgacaaggc gaattcgaac
     2821 cgagcccaaa gtcatcaaat cgacaaaagt aagaattaca agcatataga ctagaaactc
     2881 aacttcgatt ctctgaaaaa tcaaaagtcg ccccacaaca aggacttgag caaggagaaa
     2941 tgtccataca tgtaaagact ttaaactacg tacgccaaaa tgataaatta agagattgga
     3001 aaggaaaaag aaaaaccaga tataattccc agcaacaaag gcggtattcc cagctacata
     3061 gaccagcatg agcccccaga aaagccaaga taggcgctgg ttcttagtta ttaaaacacc
     3121 caaatacgtc actacaaata gaatatcaac caataaatgc caagcaggaa gctccccaat
     3181 cactacaggt aggatgggaa aaagcataaa aatcaaactg gtccaaaaca tatagtgtat
     3241 gcttttcagt ctttcaagca ttaagcattc tccttatgac cttgaaggta aatagtcaaa
     3301 ccaaataaaa ctgctgaaaa aacaagtaaa taaactgtgg ctgatagatt gatgccaccc
     3361 tcgtttaaga aggtcttgag caactccatc aattgatagg tcgggagaca cttaccaact
     3421 gcttgcatcc agtctggaaa taaagaaatg ggcatccaga gtccgcctaa aacagccaat
     3481 cctagataaa gaagattgcc cacaacagac atcagctgac tagttggtaa gagagtcaag
     3541 gtcaagccaa gtgctacaaa agcaatactc cccacaatca gcaaaatcgc agctccaacc
     3601 cattttacta gaggcatgtc tacacctctt acaaaatgtc caactgtaaa aacaaccaga
     3661 attgagacca aataatcaac cagcatactt gttatctttg atagataata ttctaccata
     3721 tttacagggc tatgatgcaa tgttttctgc cagttgttca tcttatcggt atgtaaaaca
     3781 gctggaaatg agaggatagt tgtcgacatc atggaaaagg cagtcatgga gatgaggtaa
     3841 tcacgcataa aattcgcggg ttcacctggt gtgtcctgat agataccaga aaaaaataaa
     3901 tagaaagccg tcggcatccc taccgacaat agataataga ttaattgtcg tttggtcaat
     3961 aaaaattcta tcttactaag tgctatccat cgtttcatct tagttatctc ccttctgagt
     4021 ctcttcaaag attgtattca acaaactacg attattaact tcgatttctt gcatcctaca
     4081 tcctgcttgg gctaatagtt cccagaaagc atctgcttct cgagtgacta cttgtaaaga
     4141 atcttgcttt agggtccagt tttcaaccaa atttgactgc tctacgactt ccttgtaagc
     4201 tataggaagg ataaagtgct tttctatttc ctcgctacgc atagctagag gcgtcgtatc
     4261 tcgaatcaac tctcccttat ttaagagcaa aatgcggtct gcagtgtgtt ccacttcctc
     4321 aatataatgg gacgaataga gaatggtgac tccttgcgct tttaactcct ggacaatttc
     4381 ccaaaaacgt tgacgagttg aggtatccat ggacgcagta ggctcatcta aaaaaacaat
     4441 ctttggtcgc ccaattaagg tcaagacgaa agaaaagaga cgcttttgac cgcctgataa
     4501 tttttctgcc aactgttctt tttgttgctt gacaaactgc aatagttgat caatttcctg
     4561 attgctcaaa ggatttggat agatacgttg aaagaaagca atcaactctt taacttttaa
     4621 tttctgaacg attacatttt cttgagggag gtaagcccta gtatagtcta acttagaact
     4681 cgtcactggt aaaccttgaa tagatacttg accacttgtg accagtttat ctccaagcaa
     4741 acaatctaag agtgttgtct ttccggcacc atttggacca attaaggcaa cacattcacc
     4801 atcgttgatt tcaaaggaga tgttccgcaa aatttccttg tcttttattt tcttactcaa
     4861 tttttcaact ttaaccacag tcatgagact ctcctttcaa ccactccatt cccataggga
     4921 aaacgacgaa aatcataaat ccaaacccca aagcaccatg aatgaattgg cgaagcaagg
     4981 cttgatcaaa ccaatcagta aacatttcca ctaaccatac caagagtgac aggccgataa
     5041 agaaatagat gatccctctc ttcattcttc aaactccttt ttcacatctc tgactaattt
     5101 caaaccttct ctaacaagcc aagacatgat tccaaagcca gcaaagacct tccaaggaaa
     5161 atggtagaaa tcctcatcca atcccgaaaa catgagatag gtcataactc ctgctactac
     5221 taaactcatt gcaataatca ttttatttct catctcttct tcccccattt catactacaa
     5281 ttatagtctt ttaaaatcag aggaggtaga agcttctgtc actagaaaat atgacaaatg
     5341 tcataaaaaa ttctgttcaa aacaagcaag atacactata caataaaaca caatcagaaa
     5401 aatctaaggc aacttcctca aaagagatat caaactcaat tcacaccaca atgtaaacta
     5461 atacttattt aaaatcaaaa agagtagaaa ttttt
//
LOCUS       DAVKXA010000080         5459 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKXA010000080 DAVKXA010000000
VERSION     DAVKXA010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.080"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(98..1324)
                     /locus_tag="VW883_002026"
     CDS             complement(98..1324)
                     /locus_tag="VW883_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0275091.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1396..2061)
                     /locus_tag="VW883_002027"
     CDS             complement(1396..2061)
                     /locus_tag="VW883_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0275092.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLVFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2073..2750)
                     /locus_tag="VW883_002028"
     CDS             complement(2073..2750)
                     /locus_tag="VW883_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0275093.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            complement(2772..3005)
                     /locus_tag="VW883_002029"
     CDS             complement(2772..3005)
                     /locus_tag="VW883_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275094.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            complement(3291..4135)
                     /locus_tag="VW883_002030"
                     /pseudo
     CDS             complement(3291..4135)
                     /locus_tag="VW883_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
     gene            complement(4530..5459)
                     /locus_tag="VW883_002031"
                     /pseudo
     CDS             complement(4530..5459)
                     /locus_tag="VW883_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
BASE COUNT         1898 a         1053 c          900 g         1608 t
ORIGIN      
        1 tataacacat tcagaaaaga gaaaaaagtc tgttgatttt gaccatcata aaaagactgg
       61 caatccagtc tcaaacatat attatagaaa ttctccacta aatactttca cgaatattca
      121 gaagcataac aaaggcaact agaagaaata gcaataaaac aaagctaact gccagagttc
      181 caaagctagt agcaatggtt accaaagcta ttgtaaataa gctaggtaaa acaaccgtaa
      241 tggcaccgat agaggattga actgctccca ttgactcctc aggtatttgt ttaaaaacga
      301 gttcttgcaa tctaggagag agaacacctg cgaaaaaggc atccaaggta ctaaagatga
      361 gaatccagtc aaaacgaact gtggcaaatc ctactagaag aagcaactgg atgacaagtg
      421 aggcatagag agctgttttt atggaaatgg tatgttgcag atagccactt acaaggcttc
      481 cgacaatcag ggctgacagt tcaaaagtgg atagcaaggc aagagattga cctgtttgta
      541 aattcaaaaa gggctggttc cttaaaaata gagtggaaat aggaaccgta acatttatca
      601 ctgcttgact agtagagata ataaacaaaa ccaagagcac cttattcata ttccatatca
      661 attttgatga ttggagcaaa tgctggcaaa aggattttac agagagtcct tcttgatagc
      721 taatcgtttt ttctactttc aagaggtcag tttttatgaa gaggatacct aaaaatgcga
      781 ttaaaaaggt aagagcgttc agtaaggaaa taaactggat ggatagaatg cctagtaaga
      841 ctcctcctag gatattactg attgttttca ctaaactaac agttgactgt ttaaagccaa
      901 tagcttctgc cagatggtct tgcccaataa ttctaatgaa aatcggagtg agcatggctc
      961 ctgaaaagta actcaatgtg tcagacaaga ggttaagcag acaaataaat gctactagca
     1021 acaaggagaa agactgccct gaaagtgata aagaaacgat agagtaaagc aaaaattttg
     1081 caaaactaat gactgtgtat ttcaagacac gatgatgttg aaaatctgcc aaaactccca
     1141 gaaagatttg taaaatttgg ggaagggttt ctgaaatcgt aatgagtaaa atcgccaaag
     1201 gtgcaaaaga cgcatctgcc acataattca gaaaggccag ataaaaaatc gtatccccaa
     1261 gcgttgaaat ccactggttg atagttaatt gcctaaaatc tctattttga agaaatactt
     1321 tcatcacaac tccttcttaa gttcaaatgg gaatctttcc ccaaggatag accgcgatac
     1381 tactaacaac caaaattaca gtaacatcaa aagctgacca atgccattgt agactatatg
     1441 cagtccaata ggccaataaa ttgactttgt cattctaaat aagactgcaa atataagacc
     1501 tccacccata tagaagacaa agtctgtcaa gacccaaccg tgattactaa tgtgcgagac
     1561 cccaaataaa acagcggaac caagtacatc tagcccccat ttctttcctt tttccagagc
     1621 agtcatcact aatccacgat aaatcatgtc ttcaaaaatg ggacctgcaa tcacaggata
     1681 aaaaaaatac atcaaaaatg ccgtagctcc tgtaaaagta ggagcagcat gttgataaga
     1741 aatttcattt cgagtaggtg ggaaaagaaa aaaggtgaca aaattccaag caacaaaaac
     1801 aagcagagct aggaaggaat agaaaagata ggatccttta aactttctac tattgatttt
     1861 ctgccatttc cccgaccaaa tcatagcaat aagagcaaat aaaaccacaa gaaaattcaa
     1921 catcatatcc gacagataat aggcaaagtc agatagccca gcaacaaggt cgctgcgtaa
     1981 aactaaaaca ctgaacttct ggtcagcaat aactagtaga aaaactataa taaagtagcg
     2041 gtgtgagatt atctttttca tatatcacct ttctaatatc caaataccaa taaagtaaca
     2101 atgagtaaga aactattcca tgaagcatgc agagctatag cccaatagat ggatcgggtg
     2161 tagcgaaaca tcatacaaaa tatcaagccc attccaaaat actttatgaa atctgtcgtt
     2221 atccaaccat actgcaaaac atgcatagcg ccaaatatgg cagcggaaac aagaacatca
     2281 agatagtatc tcttaacttt agataaactt gtcatcaaaa gaccacgaca aacaacctct
     2341 tctgatacag gtgcgataat actagtataa agtattcgcg taacaaaata gctaattcct
     2401 gttaaattgg tggctacttc tacgactgta cttccattct gggtacgagg aaagatatag
     2461 gttgttagat ttgcccacac gaacaataag aaaaaagaaa gaaggaaaac acccaggtaa
     2521 gaccaacgaa actggaaacg accacactct ttccaatgtt cacttttgac aaaagcaatt
     2581 gtagctatag ttcccagaat aagtaccaat aaaacttgga acacatagta catattatca
     2641 gacaaagcaa ccataaaatc taagtctgat gtgacattaa aaatgaggta ataagtcaaa
     2701 atcaacaagc cagttgctag gtgaaatttc acttctttca ttttcttcat cctattatct
     2761 cctataagag cctatcttct acggcggcca aacaatccat ctgctaaatc tatagtccaa
     2821 tcaaaagctc cacgattagg actcatccct tgattgcccc aaccagggta aattcctggg
     2881 acgccccaac cagatatacc acttcttcca ccacctccca tagaatttac gaggttgcct
     2941 cctctaacat cttgcaactc agcttctgtc aattccattg tttctgcaaa ttgtaaattt
     3001 aacatctttt acactccttc aattatcttc atttataaac cacttctgcg acctaggatt
     3061 tgcttcaagt gctttacaag tacagtataa cacgaaaatt agcttatttt agaaaatcgc
     3121 atatttgata ttttttctta tagaaatttc agatttgcga ttttggtgaa tttgattact
     3181 tctctggtat aataaagtta ctactaatga ggagtggaga aatatgaaga aacaaatttt
     3241 aacattattg aaaatcgttg ctgagattat tattattttg ccatttctaa ctaatcgata
     3301 agctttttgt attgctgaaa acgcaattca aaaagggatg ttaattgtgg attttctaat
     3361 acctgcagag attggataaa gcgttcaatc tctttttgat tgcttccctt tgtttgaaga
     3421 aagacactca tcttctttaa aaattgccac gatacttttt caaaaacatc atacggtcgt
     3481 aacatcctct ccaactcggc ttcgaagatt gggatgtagg agaaaagttt tcgctccatg
     3541 agttctgata agatatttaa gagtccttgc ttcatataca atcgattgtg tactaactct
     3601 ttaaattctt tggatttttc gagtaaggag gttgataaaa aaatcagatc ttgattgctc
     3661 aagaagggca tggtattgca aaagagatag agttcaaacc aggtccaaga ctcgatagca
     3721 tagagatagg tggtcaaaaa ctcgctatcc tcctctgcta gtgggtagct tttatttagt
     3781 gaatggatgg catctttaat cacgatggca ttcaaacgac gataggtctg cgccatctgt
     3841 tcttgatcga cttcctccaa tagctgctct aaagcagcta tatcctgatg ggcaaagcga
     3901 ttcgcatatg tggagattct tgatagttgt tgagcttgtg cccaaactca tcaaaggtca
     3961 catttatacc ttggatagct agaatcaact tatccgcaga cagcatagac tgccctagtt
     4021 caaacttgga caactgagaa gctgttagtc cagcacaagc cacatctgac tgcttgagct
     4081 ttctagccaa gcgcaattcc ttgtaaaatt cccccagttc cattttttca atcatcctac
     4141 cacctcctag cttttgcata ttatatcatt atttgtgttc atttgtcaaa acattctgac
     4201 actttggtga ttgaaaaagc cagccttaag ctgactctaa aaggaccgag ccttgtacaa
     4261 tacagaactc aatcctcgtt ctaaatagaa tgtctaactt ttttgggcag tacacgagct
     4321 tggggaacag ccactggaac gatgaggtgt gagctcaaaa tatcctccag ttatgttttt
     4381 cctaatagta taccggaaga gtgaaaggat tttataatgg agcggttaca aagaacctac
     4441 tttctattaa acagtatact atgaaaatgt gaaaatttaa catttttttg tacaaatttt
     4501 ataaattatt gcctttttaa tatcaatagt taatctctta tccagatccc ccttgtgtaa
     4561 actttatctt tataagcttc aaggccccta tcccatctat ttgcaacaat tagatcactt
     4621 tgttttataa atagttcaaa attcttttca aaaattacgt tatctatact aacgtttaaa
     4681 tttggttcat atactaaaat ttttataccg acaatcaata gttcattaat tatacttaaa
     4741 atagctgact ctttgtaatt atctgaatta tatttcatcc ccaatttata tattcctact
     4801 atctttggct ttcgttccaa tatttgttta actatgaact gttttctatt tgtgtttgaa
     4861 atatcaatcg cttctatcac tggggcattt atttctataa attctttttt taattgttta
     4921 gtatctttgg gaagacaata tcctccaaat ccaaaagaag gattattata aaaatttcca
     4981 attcttggat ctaaacaaac accttttatt acaacttcag catttaaact tctcctctca
     5041 gcaaaagaat ctagttcatt aaaaaaagca acacggagag ctaagaatgt gttagaaaaa
     5101 agcttaattg cttctgcttc agtaggagaa actaacataa catttttaat attggcagta
     5161 ctatgagtac taatcgaaag gaacaactct gcaatttttc ttccttcaac tgtctcatct
     5221 ccaacaacta tgcgacttgg atataaatta tcatatatag aacaaccttc tctcaaaaat
     5281 tcagggacaa aaatgatatt ttttgtatca aacagccttt ttaatttgtt tgaaaagccg
     5341 atcggaactg ttgactttca aataatcttt ccattaggtt ttaccctcag aatcttcgat
     5401 accgtttgtt cgatttcata tgtattaaaa ctaccaattt tctcatcata atctgtcgg
//
LOCUS       DAVKXA010000081         5336 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKXA010000081 DAVKXA010000000
VERSION     DAVKXA010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.081"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            98..901
                     /locus_tag="VW883_002032"
     CDS             98..901
                     /locus_tag="VW883_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0275095.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1017..2267)
                     /locus_tag="VW883_002033"
                     /pseudo
     CDS             complement(1017..2267)
                     /locus_tag="VW883_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2514..5209
                     /locus_tag="VW883_002034"
                     /pseudo
     CDS             2514..5209
                     /locus_tag="VW883_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         1581 a          858 c         1087 g         1810 t
ORIGIN      
        1 tagaacctat tgtgaggact ttttatagtt taagccagtt tccaaccaat ttcgtgattt
       61 actggtaatg aagaaaaaca attgaaagga tatttctatg caaccaactt acaacattga
      121 caatccaaac ttgtcttatg aagcgaagcg tgatttatgg cggataggtt ttggtctgca
      181 gaaagttgac aatctagtgc catcagcgta tatggaatct ttggctgaga aacagtcccg
      241 gggagaactg acttatgagc aggtttatga ggatgcaacg gcttatcacc atactattga
      301 tgcaagtacg gaagaggcag acttggtttc tctacgtatt gtagaactat tgtctcgaag
      361 aggctttagc tttagtcctg cgaccttact tgctattcat aaggagttgt ttcaagatat
      421 atttgaaccc tctattccgg tggggcaatt tcgtcagacc aatatcacaa agaatgaacc
      481 tgttttgaat ggtgaaagtg ttgtgtactc tgattactcc atgattcaaa tgaccttaga
      541 ttatgatttt aatcaggaaa aacaagttgc atatgcgaca ctaactcagg cggatgtggt
      601 taaacaaatc cagcatttta tttcaggaat ctggcagatt catccatttc gcgaaggaaa
      661 cactcggaca gtaacggtct ttttgattca gtatcttcgt gagtttggtt ttgatattga
      721 taatacacca tttcagcaac attccaaata ttttcgtgat gccttggtat tagataatgc
      781 aaagatttta cagcgacgtt ctgagttttt aacagctttt tttgaaaatc tcttgctcgg
      841 tggtcaaaat gatttgtctt cagaaaaaat gtatctagat ttagacctcg atttttcata
      901 atccaaatac tgagtaaaca ttgaatttta ggcaaaaatg aagtaaatat tctcacaaga
      961 aaacgtatat catcaaagtt ttaggtgtac tgaccccaaa aagttagaca aataatttat
     1021 ccgaaggatt tagttctgta ttgcacaagg ctaagtcctt ttagttttac cttaattcgt
     1081 ttattgttgt agtaatcaat atagtctaca atagcttgtt ccaattgatt aagtgattta
     1141 aatgttttct catagccata aatttcagaa tcccaaagaa ggactccatc ataccgttgt
     1201 cttggctgtt tcccttgcgt gacatggatg cttgaattcc cttactctct aagaaccgat
     1261 gataagaatc gtgttgatat tgccagcctt ggtcactatg gagaatcgta ttctcatagt
     1321 atttctctgt aaaggcctgt tctaacatac tcttcacttg ttctaagttg ggtgaagttg
     1381 aaagattata ggcgataatt tcgctgttaa agccatctaa aactggtgat aagtaaagct
     1441 tttgagtact tgctggaatg gcaaattctg tcacatctgt gtagcacttt tccattgttt
     1501 tagagccttc aaattggcct tgaatgagat tctctgcctt cttaccaacg tctcctttat
     1561 tttcgtttct gtcacatttt agcttgtaaa ttgagtactt tcatcaagtc ttgaactctt
     1621 ttatgattta ccagataagc acgatttctt agttctaaat aaattcgacg ataagcataa
     1681 tttcccttgt gttcgataaa gatggattga atttcagctt taagctcttg gtccttatct
     1741 ggtttatcta gctgtttcaa gtgatagtag taggtcgaac gagctagttt aatggctttt
     1801 agaagaagat ctaacgaaaa ctcagtcatt aattcttgaa caatttctgt ctttcttctt
     1861 tctctttttc ctccttcaat cggagttctc ttaacttttt taggatggca ttctccgatc
     1921 tcaggtactc tctctcttgt tttctcaaca atagtatacc cgtttttcct gtattgtgct
     1981 agccagttaa gaagtatcgt acgacttggg aggcagtatt caagagaaac tctatcttta
     2041 gtccagcctt catgtcagac tttattaatc atttcttgtt ttaaatcagg agaatagtaa
     2101 cgatttttcc cttttttgac gaactctatt ccgtaacgat caatcaattt aatcatgtac
     2161 ctaatattag aattgtttat cccaaattta tttgaaagct tctctaagct atatccttgt
     2221 tttctaagtt catagatctg aactttatca tcataagtta atttcataat aaaaacaccc
     2281 caaaagttag attttttctg tctaactttt ggggtgtagt tcatgtacac ctgatatgat
     2341 gcgttttttg aattttatag actgctcgtt taaactctat ttacctcgta cattccggag
     2401 cgagacggaa tattagccac atacaaaatg agtactatta ggattttatt ttcgtgtaca
     2461 atttcagcta ttcttgttat aatcagccta taggaatcaa ggaggggact cttatggctg
     2521 tttttgtgtc tttggatgga attgtggtag aagtacttga tgtcttttct tcttttaatg
     2581 gggatagtga gtttttcttg tgtaaacgtc ttaaagacaa gagtcagttt gttatggaac
     2641 gctctcagtt cgaggagatg ttccaacttc aaagtagtcg cttgacgacg caagaaaaat
     2701 tacaattgtt tacctccgtg tttgctggac gttatgatgt ttatgctaag aattttatca
     2761 atgaacaagg gaaaattcag tattttcctt cctatgatta tggttggaag cagttgccac
     2821 ctgaaaaacg gagtttccag acattgacga actccgtttt gaaatctcat tttcgtgggg
     2881 aggcagctat cggtatcttt cctatgcact tagatgatag ctgttatttt ttggtactgg
     2941 atttggatga aggagattgg aaagaagctg gtttaaccat tcgaagaata gcaagggaac
     3001 gccagatgga agcccattta gagatttctc gttcgggtta cggactccat atttggttct
     3061 tctttgagga agcgattctg agtcgaaagg ctcgcctgtt tggaaagaaa ctattagaat
     3121 tggctatgca ggaaagtatg caactgtcct ttgattcttt tgatggcatg tttccaaatc
     3181 aggatgttct tcctaaaggt ggatttgata atttaatttc ccttcctttt caaggagaag
     3241 cttatcatca agggcgaacg gtctttgtgg atgaacattt tcagccttat gaagatcaat
     3301 ggaggtatct acaagaaatt cagaggattt caactgctaa agtggcactg ttaatccaag
     3361 aggagttagg caagcaagaa ttggataagg agttgaaggt cgttttatcc aatatgatcc
     3421 aacttgaaaa atcgtctgtg acatccaagg cacttttttt cttgaaaaat atggcttcct
     3481 tttctaatcc cgaattttat agtagattga aactagaata gtatacctct gcttctaaaa
     3541 cattgttaga aatcgatttg actttcctga tcgatttgtc ctgttattat ttcattttat
     3601 tatatttaaa gcaggctatg cgacagccaa cctatcaaat tcctgagtga atgtatttat
     3661 ttggagaatc cgattattat ttatggctgc caagaggctt gttatatcca ttgcaagata
     3721 aatttaagca ggtagttgtg gaggatagga gaaaagtaca aaggtctatt agagtagcat
     3781 ttaagggaga gcttactttg gagcaagaat tagccctgtc agatatgaat tctaaagaaa
     3841 atggtttact tcatgcggga caggttttgg aaagatcgtt ttaggtgctg ctcttatctc
     3901 tgaacgtaag acaaaaacca ttatcctagt tcataataga caactcttag accaatgact
     3961 ggatcgttta aagtgttttt tgactttcga agaggcagaa gctacccgtt atacaccatc
     4021 aggtcgtgaa agggtaatag gctatgtcgg gcagtacggt ggggctaaga aatgactgag
     4081 taaactggtt gatgttgtta tgattcaatc tctatttaag ttggaaaata gtcaaagtct
     4141 tttggatgag tatgagatga tgattgtgga tgagtgtcat catatctctg ccttgatgtt
     4201 tgaaaaagtt gttgctcagt ttagagggaa gtatctttac ggtttgacgg ctacgcctga
     4261 gcgtaagaat ggtcatgaac ctattgtttt tcagagaaat tgaaaagacc aaagcaagta
     4321 attttataca gctcagtgat tggattgcta cagactcagc gaggaatcag ttgattctca
     4381 aggatattct agcccaagtg gcagaaggac ggaatatctt ggttttagtt aatcgaattc
     4441 aacagataga tgtctttgaa aagttattga aagagaaaga ggttgatgac tgttacatta
     4501 ttagcggaaa aaccaaagtc cgagaaagag aacgagttta ctggagacgt tagaacagtt
     4561 agataaaggg tttgttttgt tgtctactgg aaaatacatt ggcgaaggtt ttgacttacc
     4621 tcagttggac acgcttatct tggcagcacc cttttcttgg aaaaataatt tgattcagta
     4681 ctcaggtcgg attcatagaa actacaagga taagtctttg gtgcggattt tcgattatgt
     4741 ggatattcat gttccttatt tagaaaagat gtttcagaaa cgacaagtag cttatcgaaa
     4801 gatggattat cgtgccattg agggtgagga gaaacaattc gtttatgttg atagtagata
     4861 tgagaaggtg ttgagagagg acttagcagg ggaaagacag gaatgtctgc ttattttacc
     4921 ttatgtgcac cagacaaaac tgatgaattt tctaaaagaa tttaggatta gtcaaattga
     4981 gatatgtata ccagagacgg ttgcaaataa agcatggcta gaccagttga agagccagaa
     5041 aattaaagtg tcttttactc aatcaaaaat agtaacgcct attcttttgg tgaataagac
     5101 tattgtttgg tatggtgcaa tgccattatt agggaaggta gatgagatga ccatattacg
     5161 tttggaatca gctagtatag tttctgaact agtggcaggt ttacgataga gaaaattttt
     5221 aaaaatttct atgtatgatt ttcatttctt tagtgagact gttgccatta tcacattcga
     5281 atcacacaaa ataaaaaaat ttttataagt acttgacaaa tagattgaaa tatcat
//
LOCUS       DAVKXA010000082         5252 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKXA010000082 DAVKXA010000000
VERSION     DAVKXA010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.082"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(394..1122)
                     /locus_tag="VW883_002035"
     CDS             complement(394..1122)
                     /locus_tag="VW883_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0275096.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1280..2689
                     /locus_tag="VW883_002036"
     CDS             1280..2689
                     /locus_tag="VW883_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0275097.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2707..4002
                     /locus_tag="VW883_002037"
     CDS             2707..4002
                     /locus_tag="VW883_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0275098.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQKMEG"
     gene            4007..4315
                     /locus_tag="VW883_002038"
     CDS             4007..4315
                     /locus_tag="VW883_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0275099.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4312..4620
                     /locus_tag="VW883_002039"
     CDS             4312..4620
                     /locus_tag="VW883_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0275100.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1781 a          883 c          948 g         1640 t
ORIGIN      
        1 tcaatatatt aaaacaatat ttgaacaaat aaattgggag attgaaattc atttctagca
       61 atttgttaga agtcacagtc tactattcta acctcagtat actatatgtg ttacaagaaa
      121 agactcaaaa acttctcgtc agtgtaagaa tatttgaaac actatttaaa actaaataac
      181 tataagaagt agatcaggtg aacaatttca gtacctactc tataagctat acgaagatat
      241 ttttcaacat gatggataca acgatcactc ttttaaagcc atcttattta gaaaagagaa
      301 accatttaag catagatggg accttcttgc cctgttttaa atttttctta aactagagtc
      361 tgtaaaagat tggcttcatt ttcacatttt ctcctaggag gaatgtcgta atgcaaaaga
      421 attaaattca aataaatcat agcgatgacg actaatcgag tactcaaacg gagttccgtt
      481 atccaaataa gccacttgtt ctacttcaaa taccggttcc gttggaagga gctgcaagta
      541 atgttgctca ttttctgaac tagaagaagc tcgcaagatt tttgtagcac tggcaatatg
      601 caatcctaac tttccttcaa tgtaattgta aatcgatttt tgtaaaatat cttcagtaat
      661 acctggaata acatcggtac tcatataagt ttgttccaga acataaggtt taccgtcaat
      721 aatacgcaga cggtaaatat tataaactgg actctgcaaa gcgacctgta gtttttctgc
      781 taaaaattca tttgcaaatt ctaatttgaa gtgaataatc ctcgagtcaa ttgtagaatg
      841 agcatcttca gatatttttg tcagtccccg gatatctctt tctggaacga ttaattttct
      901 ttttgagctg ccacgagaga gaacaaaggt tccctgccca cgttttctaa aaattaagcc
      961 ctcagaaact aacaagtcta aagctttttt gatcgtcatt cgactacagg caaactgttt
     1021 agctaatgtc atttcatcag gcaattgttc gttcatggta tatttattac aaagaatctt
     1081 ttcacgaatc tcattgtaaa taaataaata ttttgtactc atttaatctg gttctctcta
     1141 taatattcta atagtagtat aacaaagttc aagaaatgag gcaaacacaa gatatgtata
     1201 aacaattttt aaaaatgtct agacaaattt gaaaattatg ctatacttta tgtatagaat
     1261 aatagaaagg aggttgagca tgaaaaaaaa gttagtattt cctaatctat tttggtgggg
     1321 agctgcttct agcggacctc agacagaagg tcaatatgga aaagtacatg aaaatgtgat
     1381 ggactactgg ttcaaaacgc atccagaaga ttttttcgat aatgtcggac ctcttgtagc
     1441 cagtaacttt tttcatactt acaccgaaga tttccacttg atgaaggaaa ttggagttaa
     1501 ttctttccgc acttccatcc aatggagtcg actcatcaag aatttagaga caggtgagcc
     1561 tgatccaaaa ggtattgctt tctacaatgc catcattgaa gaagctaaaa agaaccagat
     1621 ggatcttgtg atgaatttac atcattttga tttaccagtg gaacttcttc aaaaatacgg
     1681 tggttgggaa agcaaacatg tagtggagtt attcgtgaag tttgccaaga ctgctttcac
     1741 atgctttgga gataaggttc attactggac aactttcaat gagccaatgg tcattccaga
     1801 agcaggatac ttatatgctt tccattatcc aaatctaaaa ggaaagggaa aagaggccgt
     1861 acaagtcatc tataatctaa accttgctag tgcaaaagtg attcaactat atcgctcatt
     1921 agaacttgat ggaaagattg ggattatttt aaacttgaca cctgcttatc caagaagtaa
     1981 ttctccagaa gacttagaag caagtcgatt tacagatgac ttctttaaca aagtcttctt
     2041 gaatccagct gttaaaggaa ctttcccaga aagattggta aaacagctag agagagatgg
     2101 cgtgttatgg agtcataccg aaaaagagct tcaactgatg aaatcaaata cggttgattt
     2161 tcttggagta aactactacc atccaaaacg tgttcaagca caagcaaatc ctgaggaata
     2221 tcagacgccc tggatgccag accaatactt caaagagtat gaatggctgg agcgtcgcat
     2281 gaatccatat cgtggttggg aaatttttcc gaaagccatt tatgatattg ctatgattgt
     2341 gaaggaagaa tatggtaata tcccatggtt tatcagtgaa aacggaatgg gtgttgaaaa
     2401 cgaagcacgg tttatcgatg aaaatggagt tatcgatgac gtgtatcgta ttgaatttta
     2461 tgaagaacat ttaagatggc tacataaagc cattgaagag ggaagtcact gttttggata
     2521 ccacgcttgg accgcatttg attgctggtc ttggaataat gcatataaga atcgttacgg
     2581 atttatctcc gttgatttag aaacgcaaaa gagaaccatc aagagctcag gaagatggta
     2641 tcgcaaagta agtgacaata acggttttga agtagaaatt gaggagtaaa gagaggagat
     2701 attcagatga aaaactcaaa atttatagat caatttgcca cctttgctgg taaactaggg
     2761 aaccaaattc atttaaaaac cctaagagat gcattcgtaa cagtaatgcc attatatatt
     2821 ttggcaggtt taatcgttct tttgaacaac acggtattta agtggatttt ccaaggggat
     2881 acattaacaa gattccaata ttggggaata acaattgcaa acggtacttt aagtatttca
     2941 ggtatgatta ttgctgtaat ggttggttat ttcttagcta aaaacagaga tttcgaaaac
     3001 ccgttagcag catcaatgct atcattagtt tctttaattg tgatgatgcc aaatacagtt
     3061 tctgtagttc ctgacggagc aaaagatgcg gtaaacattt caggtgttct ttcattcaac
     3121 aacacaggta caggcgcaat gttcgccggg gttatcgtag cgattattgc aacagaatta
     3181 ttcattgaat tatcaaacgt taaagcttta caaatgaacc ttggtgaaaa tattccacca
     3241 gctgttagta gatcatttag cgtattactt ccagtcatga ccgtcatctc cttatttggg
     3301 gttgtttcag cattattatt caatataact ggaatgaact taatctcaat cattacaatc
     3361 tttattcaag aaccaattcg tcatattggt acaagcttaa tcggggtcat tattatttac
     3421 tctttaggaa atatgttatg gctatttggt attcaccaag cagttattta cagtgccatc
     3481 ctagaaccat tactattaat taacattact gaaaacatca ctgcagcaaa taatggacaa
     3541 gccattccac acatcatcaa cctatcacaa atacaaacat tcgctttaat gggtggtagt
     3601 ggatctacat tatgtttatt aatagcaaca ttcttagtaa gtcgcaatgc tgtttctaaa
     3661 aacgtggcta aattatcttt tggacctggt atcttcaata tcaatgaacc agtattattc
     3721 ggttacccaa tcgtttataa catttcatta gctattccat ttatcacagt tccagtcctt
     3781 ggtattttaa tcagctactt agcaacagtt acaggattca tgagtcctgc atttatacaa
     3841 gttccttgga ctacaccagt attcttaaat gcatggttag caacagcagg ggacgtgaga
     3901 gcagttctag ttcaattcat catctttgca cttggagttc ttctatacat tccatttatc
     3961 aaagttaatg acaaagttgt tgaacaaaaa atggaaggtt aagattatga aacaaatttt
     4021 attagtatgt aatgcgggaa tgtcgacaag tatgcttgtt aaaaaaatgc aacaaagtgc
     4081 gactgaacgt gggattgaaa tttctatcca agcaaaatca atgacagaag ctaaaaagaa
     4141 tatccatgaa gcagatgtca ttctaattgg gccacaaatt cgttatgagt tacttgctgt
     4201 gaaagaaatt gcaggaaata tccctgtaga taccattgat atgcgggatt acggaatgat
     4261 gaatggagca aaagttctgg aacaagcact tgcatggata ggagaaataa gatgacagaa
     4321 gaaatggaat atatctgttt tcagctcatt gccaatagtg gagcagccaa atcatccttt
     4381 attgaagcca tccaactagc taaggcagga aatttaaaag aagcgaaaat taaagttgaa
     4441 gaagcggaag actccttagt agaagcgcac aagattcact ctaatctcat acaaaaagaa
     4501 gctactggag aaaaaatagg attctccttg ctatttatgc atgcagaaga ccaaatggct
     4561 tcaacagaga ttattcagtt gctatctaaa gaattcatcg atctctatca aaataaatag
     4621 gaacactgtc attcccatct gtctttatta atgacgacta cattgtagga acctccaaaa
     4681 gttggacaaa atgattgaaa ggattggatc ctgcattaca caagatccaa tccttttctt
     4741 ttactctagt ttttataata tgttgaatct agaatagtcc acagcagttt ctaaaaaatt
     4801 tctggaaatg gatgttaagc tccaatttat ttgtttatat cttatttcag tttactatac
     4861 tagcttatta ttctagtgaa aaattgaatg agccactatt tatttaatat gtatgatgag
     4921 ggaatgactc aaaaacttct tgtcgatata agaacatctg agatagtatt ttaaaacgaa
     4981 aggactataa aagctcattt ccttcgcact tattttatag agatctatca ttatactctt
     5041 tagaaatcaa aaagcaacac accttgtcat cgttttatcg taaatctgtt aatgagggag
     5101 ctagtcttat ctgcaatctc aaatcagtgt tttgagctga atggcactcg ttttctcgtt
     5161 tgctctttga ttttaattgg gccttagtaa atactactct taaattaaac tatagtgaat
     5221 tgaaataaga tgtgaacaac tctatcagga aa
//
LOCUS       DAVKXA010000083         5071 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKXA010000083 DAVKXA010000000
VERSION     DAVKXA010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.083"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            217..480
                     /locus_tag="VW883_002040"
     CDS             217..480
                     /locus_tag="VW883_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0275101.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            486..2219
                     /gene="ptsP"
                     /locus_tag="VW883_002041"
     CDS             486..2219
                     /gene="ptsP"
                     /locus_tag="VW883_002041"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0275102.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            2474..4924
                     /gene="phtA"
                     /locus_tag="VW883_002042"
     CDS             2474..4924
                     /gene="phtA"
                     /locus_tag="VW883_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV0275103.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTLRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
BASE COUNT         1722 a          945 c         1058 g         1346 t
ORIGIN      
        1 tgaaatagca atgattatcc tataaattgt ttttgaagaa actatatcct gtgttttgtt
       61 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
      121 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
      181 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
      241 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
      301 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
      361 ggtgttatga gtcttggtgt tggtcaaggt gctgacgtaa ctatctcagc tgaaggtgca
      421 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
      481 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
      541 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
      601 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
      661 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
      721 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
      781 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
      841 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
      901 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctatcaat gaagaagtga
      961 ttgtgattgc gcatgacttg actccttcag atacagctca attggacaaa aactttgtaa
     1021 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
     1081 ttgaaattgc tgctgtatta ggtacaaaca acatcactga aatcgttaaa gacggtgaca
     1141 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
     1201 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
     1261 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
     1321 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
     1381 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
     1441 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
     1501 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
     1561 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
     1621 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
     1681 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
     1741 ctgaaggtgt tgcagttgcg gataacattc aagttggtat catgatcgag attcctgcag
     1801 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
     1861 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
     1921 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
     1981 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
     2041 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
     2101 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
     2161 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
     2221 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
     2281 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
     2341 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
     2401 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
     2461 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
     2521 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa
     2581 tcgtgtttcc tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga
     2641 tgaggttagc aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca
     2701 aggctatgtc acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga
     2761 tgcgattttc agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga
     2821 tattgttaat gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta
     2881 ccttaaggat gctgcccacg cggataacgt ccgtacaaaa gaggaaatca atcgacaaaa
     2941 acaagaacat agtcaacatc gtgaaggtgg gactccaaga aacgatggtg ctgttgcctt
     3001 ggcacgttcg caaggacgct atactacaga tgatggttat atctttaatg cttctgatat
     3061 catagaggat actggtgatg cttatatcgt tcctcatgga gatcattacc attacattcc
     3121 taagaatgag ttatcagcta gcgagttggc tgctgcagaa gccttcctat ctggtcgggg
     3181 aaatctgtca aattcaagaa cctatcgccg acaaaatagc gataacactt taagaacaaa
     3241 ctgggtacct tctgtaagca atccaggaac tacaaatact aacacaagca acaacagcaa
     3301 cactaacagt caagcaagtc aaagtaatga cattgatagt ctcttgaaac agctctacaa
     3361 actgcctttg agtcaacgac atgtagaatc tgatggcctt gttttcgacc cagcgcaaat
     3421 cacaagtcga acagctagag gtgttgcagt gccacacgga gatcattacc acttcatccc
     3481 ttactctcaa atgtctgaat tggaagaacg aatcgctcgt attattcccc ttcgttatcg
     3541 ttcaaaccat tgggtaccag attcaaggcc agaacaacca agtccacaac cgactccgga
     3601 acctagtcca ggcccgcaac ctgcaccaaa tcttaaaata gactcaaatt cttctttggt
     3661 tagtcagctg gtacgaaaag ttggggaagg atatgtattc gaagaaaagg gcatctctcg
     3721 ttatgtcttt gcgaaagatt taccatctga aactgttaaa aatcttgaaa gtaagttatc
     3781 aaaacaagag agtgtttcac acactttaac tgctaaaaaa gaaaatgttg ctcctcgtga
     3841 ccaagaattt tatgataaag catataatct gttaactgag gctcataaag ccttgtttga
     3901 aaataagggt cgtaattctg atttccaagc cttagacaaa ttattagaac gcttgaatga
     3961 tgaatcgact aataaagaaa aattggtaga tgatttattg gcattcctag caccaattac
     4021 ccatccagag cgacttggca agccaaattc tcaaattgag tatactgaag acgaagttcg
     4081 tattgctcaa ttagctgata agtatacaac gtcagatggt tacatttttg atgaacatga
     4141 tataatcagt gatgaaggag atgcatatgt aacgcctcat atgggccata gtcactggat
     4201 tggaaaagat agcctttctg ataaggaaaa agttgcagct caagcctata ctaaagaaaa
     4261 aggtatccta cctccatctc cagacgcaga tgttaaagca aatccaactg gagatagtgc
     4321 agcagctatt tacaatcgtg tgaaagggga aaaacgaatt ccactcgttc gacttccata
     4381 tatggttgag catacagttg aggttaaaaa cggtaatttg attattcctc ataaggatca
     4441 ttaccataat attaaatttg cttggtttga tgatcacaca tacaaagctc caaatggcta
     4501 taccttggaa gatttgtttg cgacgattaa gtactacgta gaacaccctg acgaacgtcc
     4561 acattctaat gatggatggg gcaatgccag tgagcatgtg ttaggcaaga aagaccacag
     4621 tgaagatcca aataagaact tcaaagcgga tgaagagcca gtagaggaaa cacctgctga
     4681 gccagaagtc cctcaagtag agactgaaaa agtagaagcc caactcaaag aagcagaagt
     4741 tttgcttgcg aaagtaacgg attctagtct gaaagccaat gcaacagaaa ctctagctgg
     4801 tttacgaaat aatttgactc ttcaaattat ggataacaat agtatcatgg cagaagcaga
     4861 aaaattactt gcgttgttaa aaggaagtaa tccttcatct gtaagtaagg aaaaaataaa
     4921 ctaatgaaaa atgaaagtct cgataaagag gctttcattt ttattatgta tatatgtaaa
     4981 attcttgaca agcaatatta aaaagagtaa actattaact agttaattaa ccggtttatt
     5041 actttatagt gaatcaaata tacttaagaa a
//
LOCUS       DAVKXA010000084         4895 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKXA010000084 DAVKXA010000000
VERSION     DAVKXA010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.084"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            28..1573
                     /locus_tag="VW883_002043"
     rRNA            28..1573
                     /locus_tag="VW883_002043"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1625..1697
                     /locus_tag="VW883_002044"
     tRNA            1625..1697
                     /locus_tag="VW883_002044"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1658..1660,aa:Ala,seq:tgc)
     gene            1822..4723
                     /locus_tag="VW883_002045"
     rRNA            1822..4723
                     /locus_tag="VW883_002045"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4800..>4895
                     /gene="rrf"
                     /locus_tag="VW883_002046"
     rRNA            4800..>4895
                     /gene="rrf"
                     /locus_tag="VW883_002046"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1358 a         1002 c         1452 g         1083 t
ORIGIN      
        1 tgacagaaat gagtgagaac tcaaactttt aatgagagtt tgatcctggc tcaggacgaa
       61 cgctggcggc gtgcctaata catgcaagta gaacgctgaa ggaggagctt gcttctctgg
      121 atgagttgcg aacgggtgag taacgcgtag gtaacctgcc tggtagcggg ggataactat
      181 tggaaacgat agctaatacc gcataagagt agatgttgca tgacatttgc ttaaaaggtg
      241 cacttgcatc actaccagat ggacctgcgt tgtattagct agttggtggg gtaacggctc
      301 accaaggcga cgatacatag ccgacctgag agggtgatcg gccacactgg gactgagaca
      361 cggcccagac tcctacggga ggcagcagta gggaatcttc ggcaatggac ggaagtctga
      421 ccgagcaacg ccgcgtgagt gaagaaggtt ttcggatcgt aaagctctgt tgtaagagaa
      481 gaacgagtgt gagagtggaa agttcacact gtgacggtat cttaccagaa agggacggct
      541 aactacgtgc cagcagccgc ggtaatacgt aggtcccgag cgttgtccgg atttattggg
      601 cgtaaagcga gcgcaggcgg ttagataagt ctgaagttaa aggctgtggc ttaaccatag
      661 taggctttgg aaactgttta acttgagtgc aagaggggag agtggaattc catgtgtagc
      721 ggtgaaatgc gtagatatat ggaggaacac cggtggcgaa agcggctctc tggcttgtaa
      781 ctgacgctga ggctcgaaag cgtggggagc aaacaggatt agataccctg gtagtccacg
      841 ctgtaaacga tgagtgctag gtgttagacc ctttccgggg tttagtgccg tagctaacgc
      901 attaagcact ccgcctgggg agtacgaccg caaggttgaa actcaaagga attgacgggg
      961 gcccgcacaa gcggtggagc atgtggttta attcgaagca acgcgaagaa ccttaccagg
     1021 tcttgacatc cctctgaccg ctctagagat agagttttcc ttcgggacag aggtgacagg
     1081 tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg
     1141 caacccctat tgttagttgc catcatttag ttgggcactc tagcgagact gccggtaata
     1201 aaccggagga aggtggggat gacgtcaaat catcatgccc cttatgacct gggctacaca
     1261 cgtgctacaa tggctggtac aacgagtcgc aagccggtga cggcaagcta atctcttaaa
     1321 gccagtctca gttcggattg taggctgcaa ctcgcctaca tgaagtcgga atcgctagta
     1381 atcgcggatc agcacgccgc ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac
     1441 accacgagag tttgtaacac ccgaagtcgg tgaggtaacc gtaaggagcc agccgcctaa
     1501 ggtgggatag atgattgggg tgaagtcgta acaaggtagc cgtatcggaa ggtgcggctg
     1561 gatcacctcc tttctaagga taaggaactg cgcattggtc ttgtttagtc ttgagaggtc
     1621 ttgtggggcc ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc
     1681 gatcccgcta ggctccattg gtgagagatc accaagtaat gcacattgaa aattgaatat
     1741 ctatatcaaa tagtaacaag aaaataaacc gaaaacgctg tagtattaat aagagtttat
     1801 gactgaaagg tcagaaaata aggttaagtt aataagggcg cacggtggat gccttggcac
     1861 taggagccga cgaaggacgt gacaaacgac gatatgcctt gggtagctgt aagtaagcga
     1921 tgatccaggg atttccgaat gggggaaccc aacaggtagt acctgttacc cacatctgtt
     1981 aaggatgtga ggaggaagac gcagtgaact gaaacatcta agtagctgca ggaagagaaa
     2041 gcaaaagcga ttgccttagt agcggcgagc gaaacggcag gagggcaaac cgaagagttt
     2101 actcttcggg gttgtaggac tgcaatgtgg actcaaagat tatagaagaa tgatttggga
     2161 agatcagcca aagagagtaa tagcctcgta tttaaaatag tctttgtact tagcagtatc
     2221 ctgagtacgg cgggacacgt gaaatcccgt cggaatctgg gaggaccatc tcccaaccct
     2281 aaatactccc tagtgaccga tagtgaacca gtaccgtgag ggaaaggtga aaagcacccc
     2341 gggaggggag tgaaatagaa cctgaaaccg tgtgcctaca acaagttcga gcccgttaat
     2401 gggtgagagc gtgccttttg tagaatgaac cggcgagtta cgttatgatg cgaggttaag
     2461 ttgaagagac ggagccgtag ggaaaccgag tctgaatagg gcgccttagt atcatgacgt
     2521 agacccgaaa ccatgtgacc tacccatgag caggttgaag gtgcggtaag acgcactgga
     2581 ggaccgaacc agggcacgtt gaaaagtgct tggatgactt gtgggtagcg gagaaattcc
     2641 aaacgaactt ggagatagct ggttctctcc gaaatagctt tagggctagc gtcgacatta
     2701 gagattcttg gaggtagagc actgtttggg tgaggggtcc atcccggatt accaatctca
     2761 gataaactcc gaatgccaat gaattatggt cggcagtcag actgcgagtg ctaagatccg
     2821 tagtcgaaag ggaaacagcc cagaccacca gctaaggtcc caaaataatt gttaagtgga
     2881 aaaggatgtg gggttgcaca gacaactagg atgttagctt agaagcagct attcattcaa
     2941 agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc ggggctaaaa
     3001 caatttaccg aagctgtgga tacctttata ggtatggtag gagagcgttc tatgtgtgat
     3061 gaaggtatac cgtgaggagt gctggaacgc atagaagtga gaatgccggt atgagtagcg
     3121 aaagacaggt gagaatcctg tccaccgtaa gactaaggtt tccaggggaa ggctcgtccg
     3181 ccctgggtta gtcgggacct aaggagagac cgaaaggtgt atccgatgga caacaggttg
     3241 atattcctgt actagagtat gtagtgatgg agggacgcag taggctaact aaagcagacg
     3301 attggaagag tctgtctaag cagtgaggtg tgaattgagt caaatgctta attctataac
     3361 attgagctgt gatggggagc gaagtttagt agcgaagtta gtgacgtcac actgccaaga
     3421 aaagcttcta gcgtttaaac atactctacc cgtaccgcaa accgacacag gtagtcgagg
     3481 cgagtagcct caggtgagcg agagaactct cgttaaggaa ctcggcaaaa tgaccccgta
     3541 acttcgggag aaggggtgct gacttaaagt cagccgcagt gaataggccc aagcaactgt
     3601 ttatcaaaaa cacagctctc tgctaaatcg taagatgatg tatagggggt gacgcctgcc
     3661 cggtgctgga aggttaagag gagtgcttag cgtaagcgaa ggtatgaatt gaagccccag
     3721 taaacggcgg ccgtaactat aacggtccta aggtagcgaa attccttgtc gggtaagttc
     3781 cgacccgcac gaaaggcgta atgatttggg cactgtctca acgagagact cggtgaaatt
     3841 ttagtacctg tgaagatgca ggttacccgc gacaggacgg aaagacccca tggagcttta
     3901 ctgcagtttg atattgagtg tctgtaccac atgtacagga taggtaggag tctaagagat
     3961 cgggacgcca gtttcgaagg agacgctgtt gggatactac ccttgtgtta tggccactct
     4021 aacccagata ggtgatccct atcggagaca gtgtctgacg ggcagtttga ctggggcggt
     4081 cgcctcctaa aaggtaacgg aggcgcccaa aggttccctc agaatggttg gaaatcattc
     4141 gcagagtgta aaggtataag ggagcttgac tgcgagagct acaactcgag cagggacgaa
     4201 agtcgggctt agtgatccgg tggttccgta tggaagggcc atcgctcaac ggataaaagc
     4261 taccctgggg ataacaggct tatctccccc aagagttcac atcgacgggg aggtttggca
     4321 cctcgatgtc ggctcgtcgc atcctggggc tgtagtcggt cccaagggtt gggctgttcg
     4381 cccattaaag cggcacgcga gctgggttca gaacgtcgtg agacagttcg gtccctatcc
     4441 gtcgcgggcg taggaaattt gagaggatct gctcctagta cgagaggacc agagtggact
     4501 taccgctggt gtaccagttg tcttgccaaa ggcatcgctg ggtagctatg tagggaaggg
     4561 ataaacgctg aaagcatcta agtgtgaaac ccacctcaag atgagatttc ccatgattat
     4621 atatcagtaa gagccctgag agatgatcag gtagataggt tagaagtgga agtgtggcga
     4681 cacatgtagc ggactaatac taatagctcg aggacttatc caaagtaact gagaatatga
     4741 aagcgaacgg ttttcttaag ttgaatagat attcaatttt gagtaggtat tactcagagt
     4801 taagtgacga tagcctagga gatacacctg tacccatgcc gaacacagaa gttaagccct
     4861 agaacgccgg aagtagttgg gggttgcccc ctgtg
//
LOCUS       DAVKXA010000085         4506 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKXA010000085 DAVKXA010000000
VERSION     DAVKXA010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.085"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..612)
                     /locus_tag="VW883_002047"
     CDS             complement(<1..612)
                     /locus_tag="VW883_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0275104.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKK"
     gene            complement(794..1756)
                     /gene="nrdF"
                     /locus_tag="VW883_002048"
     CDS             complement(794..1756)
                     /gene="nrdF"
                     /locus_tag="VW883_002048"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0275105.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(1944..4103)
                     /gene="nrdE"
                     /locus_tag="VW883_002049"
     CDS             complement(1944..4103)
                     /gene="nrdE"
                     /locus_tag="VW883_002049"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0275106.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4184..4402)
                     /gene="nrdH"
                     /locus_tag="VW883_002050"
     CDS             complement(4184..4402)
                     /gene="nrdH"
                     /locus_tag="VW883_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0275107.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
BASE COUNT         1304 a          838 c          918 g         1446 t
ORIGIN      
        1 ttttttatta gaattattta aagcgatgcg ttgagcctct ccctcttcct cgctaaaagt
       61 agctagagct ccgttttgaa taccattaca gctaacgaaa gctttagaaa attggagatt
      121 agagagattt tgtagggtca atgtgccaac aaaagcacct gtaatatcgc gataatttcc
      181 acctatcaaa atcaaatctg ttaattttcg ttcgcttaaa atcagaaaaa caggtagact
      241 gttggttacg acgcggatat tgtcaatagg caactcacgc gcaaaaaact ctaatgttgt
      301 tcctggtcca atgaaaatag tttctctttc ttctactaga ctgcctgcaa aatgggctat
      361 ttcttgtttt tctgccgttt ggagggcttg tttttcaata tttgatcgct cattagtcaa
      421 aagggagttg gttcgaagtt tttcagctcc accatgcaca cgaatcagca aatctttatc
      481 agctaattcc tgtaaatagc gccttgcagt catatctgaa acggctattt cgtccataat
      541 ctgtttaact gttatggttc ctttactatt tactatctct aaaattttgg ttaatttttc
      601 ttgtttgagc atattatcac ctcgtttcct actactatct taccataaac aaactcatca
      661 ttcaaataca aaaacaacaa aatgaaacaa aaacaaaaat atcgaagttt gttttcaaaa
      721 ctttcgatat ttttgttggg ttataacttt gatgtttcta gtttactttt tgatgattga
      781 gagtgatgga gaattagtct aaaccgtagt tatagtcatc gtcttgcatg gcttcaactt
      841 cgccaagaag gtaaccattt ccgacttgag agaagaagtc atggttggaa gttcctgttg
      901 aaataccgtt cataacgatt gggttgacat cttcagctga atctgggaaa agtggatctt
      961 gtcccatgtt catgagagct ttattggcat tgtagcgaag gaaggtttta acctcttcag
     1021 tccaaccaac accgtcataa agactctctg tgtagccttc ttcattttca taaagagtat
     1081 agagtaggtc gtacatccat tctttgagtt tttcttgctc ttcttcaggc aattcattga
     1141 aaccaagttg gaatttgtaa ccaatgtagg ttccgtgaac agactcgtca cgaataatca
     1201 atttaatgat ttctgcaacg ttggctagtt tgttgttacc gagatagtag aggggagtga
     1261 agaaaccaga gtagaagagg aaggtttcga ggaagacgct ggcaactttc ttttcaagtg
     1321 ggctgccgtt taggtagatt tcgttgacaa tctcagcctt cttttgtagg taaggattgg
     1381 tattggtcca ttcgaaaatt tcttcaatct cagccttagt attcaaggta gaaaagattg
     1441 atgagtaaga tttagcgtgg acagattcca taaattggat gttattgaaa acagcttcct
     1501 catgtggtgt acggatgtct gcgcgaaggg cttgaacccc agtttcagat tgcatagtgt
     1561 caagaagggt taaaccacca aaaacttttc cgaccaagtc tttctctttg ttagatagct
     1621 ttctccagtc atccaagtcg tttgataagg gaatacgtgt atcgagccaa aattgctccg
     1681 tcagtttttc ccaagttgat ttgtcgatga catcttcgat ggcattccag ttaatggctt
     1741 tgtagtaagt ttccatttaa aatctctttc tgtgtttagt attgcgaact cacaattatt
     1801 tctactttac cataattcta taggagtatc gcacaaaaag tcggaagccc gacttttaaa
     1861 atgttacata aattatgtta tgacatagta gatttgattt tatctgtgct gcttagggaa
     1921 aaataatgtt tctatgctag aaactaaatc acacagcttt cacattggtt ggcgccgact
     1981 tctccaccgt catctgtaaa ggtacggacg tagtagatag acttgattcc cttgttaaag
     2041 gcatagttac gaaggatgga caagtcacgt gtcgtttgtt tattttccct cttccattcg
     2101 taaaggcctt ttggaatgtc actacgcatg aagagggtga gtgaaagtcc ttgatccacg
     2161 tgttcagtcg cagcagcgta aacatcgatg actttacgca tatccatatc gtaggcagaa
     2221 gtgtagtaag gaatggtttc tgtagacaag ccagcagcag ggtagtagat tttaccaatt
     2281 ttcttctctt ggcgttcttc gatacgttgc gtaatcgggt ggatagaagc agaaacgtcg
     2341 ttgatatagc tgatagaacc atttggcgct acagcaaggc gattttggtg gtaaagacca
     2401 tcttcttgaa ccttgtcgcg aagttcagcc caatcagcaa caccagggat aaagacattt
     2461 ttgaagagtt ctttaacacg gtctgatgtt ggaacaaatt caccagttac atacttgtca
     2521 aagtaacttc cgttagcata gtctgatttt tcaaagttgt ggaaggtaat accacgttca
     2581 cgcgcaatat tgtttgactc taccaaggtc cagtagttca taagcataaa gtagatgctt
     2641 gtaaattcaa cagactcagg tgaaccatat tcaatgagtt gttgggcaag gtagctgtgc
     2701 agtcccatgg caccgagacc aaaggtgtgg gcttggctat ttccatggtc aatcgttggt
     2761 acagctacga tatgtgaact atctgtaacg aaagtaaggg cacgaaccat agcacggata
     2821 gaacgaccaa aatcaggtga agtcatcatg ttaaccacgt tggttgaacc caggttacat
     2881 gaaacatctg ttcccatttg aaggaattct tgagcatcgt tgatcaagct tggttcttga
     2941 acttgaagaa tctcagaaca caagttactc atgataatct ttccatcaac aggatttgca
     3001 cggttagccg tatctatgtt gactacataa ggatagccag actcttgttg caatttagag
     3061 atttcagttt ccaaatcccg cgccttgatt tttgtcttgc gaatatttgg atttgcgacc
     3121 aattcatcgt atttttcagt aatgtcgatg taattgaatg gcacaccgta ttctttttct
     3181 acagagtaag ggctgaagag gtacatttct tcatttttac gagccaattc gtagaattta
     3241 tcaggtacta caacaccaag tgatagagtc ttgacacgta ctttttcatc agcgttttct
     3301 ttcttagttg aaaggaaagc gatgatatct gggtgaaaga cgttgaggta gacaacaccg
     3361 gcaccttgac gttgccccaa ttggttggag taagagaagc tgtcttcaaa aagcttcata
     3421 acaggaacga cacctgaagc agctccttca tagcctttga taggtgcacc agcttcacga
     3481 aggttgctga gagtaattcc cacaccacca ccaatacgtg aaagttgaag agctgagttg
     3541 atagaacgtc cgatagagtt catatcatcc gtcacttgga ttaggaaaca agataccaac
     3601 tccccacgac gagcacgtcc agcattcaag aaggaaggag tagcaggttg gtagcgttgg
     3661 tggatgattt cattggcaat atcgattgca acagcttcat tcccatcagc gaaataaagg
     3721 gcgttgaaga agacacggtc ttccatattt tcaagatagt attcaccgtc attagtcttt
     3781 aaggcatatt gattgtaaaa tttataagct gccatgaatg acttgaattg gaagttttgg
     3841 tctttgataa attgagccaa ttcttccaag aactctggac ggtatttctt gataaaggct
     3901 gtttcgatgt agttgtgttc aatgaggtaa ttgattttgt ctttgattga atcaaaaacc
     3961 atagtgtttg gaactacatt ttctttaaag aaagcatcca aggcttcctt atctttatga
     4021 agcatgattt gtccattaac aggacggtta atttcgttat taagacggaa gtaagtcacg
     4081 tcttcaagat gttttaatcc cataaaattt cccttatcta attacaaaag aaaggcttct
     4141 aagttagccc taaaagcagt ttcttctgga tgatgtacta agattatgct aattgtttca
     4201 gttttcctgg ttggaaacct gaaaagactt cagttggtgt ttggataaca ggagctgcgc
     4261 taaaaccgag ctctttaact tgatcgacgt actcaggttg ctcatcaaga ttgatttcac
     4321 gataagagac attattactg tccaagaaac gcttggtcat tttacattgg acacaattgt
     4381 ttttagaata aacggttacc attgtgtaac tcctcttcaa aatttaatac tatcttagta
     4441 tatcagaaaa taaaattttg tcaatgattt aaactaaata tagtggtgtt cttttgttgt
     4501 ttttat
//
LOCUS       DAVKXA010000086         4436 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKXA010000086 DAVKXA010000000
VERSION     DAVKXA010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4436
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.086"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..721
                     /locus_tag="VW883_002051"
     CDS             <1..721
                     /locus_tag="VW883_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0275108.1"
                     /translation="NFKIEDDNGDNLKISVKFSLIDLEAEFDYINARGRSKQDFIEKM
                     IGSFEEVVDSIFDEDSLAFNGNRDKFSHIEHFFTTNFYEYSFEIEYQGDKFEQMSPGK
                     KAFIVLKLILEFSDSKIPVLIDQPEDSLDNRAIYSELTKYIKKTKKNRQIIIVTHNPN
                     IVVSGDAENIIVANQQSDNSPNQNGKKFDYVNGALENRNNDSTSEFILQKYNIREHVC
                     DILEGGEDAFIKRENKYSING"
     gene            854..1186
                     /locus_tag="VW883_002052"
     CDS             854..1186
                     /locus_tag="VW883_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0275109.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            1198..2769
                     /gene="ffh"
                     /locus_tag="VW883_002053"
     CDS             1198..2769
                     /gene="ffh"
                     /locus_tag="VW883_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0275110.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTVEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRLAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(2964..4247)
                     /locus_tag="VW883_002054"
     CDS             complement(2964..4247)
                     /locus_tag="VW883_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0275111.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
BASE COUNT         1472 a          764 c          975 g         1225 t
ORIGIN      
        1 taatttcaag attgaagatg ataatggaga taatctaaag atttcagtca agttctcatt
       61 aattgatttg gaggctgaat ttgattatat taatgctcga ggtcgttcga aacaagattt
      121 tatagaaaaa atgataggtt cttttgaaga agttgttgat tcaatatttg acgaggatag
      181 tcttgcgttt aatggaaata gggataaatt cagtcacatt gagcatttct tcactactaa
      241 tttttacgaa tatagttttg agattgaata tcaaggtgat aaatttgaac aaatgtctcc
      301 tggtaaaaaa gcgtttattg tattaaaatt aatattagag ttttcagata gtaaaatccc
      361 cgtattaatt gatcagcctg aagatagttt ggataatagg gcaatatata gtgaattgac
      421 aaaatacatc aaaaaaacta aaaagaatcg acaaataatc atagttactc acaatcctaa
      481 tatagttgta tctggtgatg cagaaaatat tattgtagct aatcagcaat ctgataattc
      541 tccaaatcaa aatggtaaga agtttgatta tgtaaatggt gctttagaga accgtaataa
      601 tgattctaca tctgaattca tacttcaaaa atacaacatc agggaacatg tatgtgatat
      661 tttggaaggt ggagaagacg cctttattaa gagggaaaat aaatacagta ttaatggcta
      721 ataataattg tattaattaa aaatggagag cattaattta taaaagacac atatttagtt
      781 ctagcaaaca gtctttttaa ggagttagga ttggtaattg gactgccggg taatgtgtgg
      841 tataataaaa gttatggaaa tcgaaaaaac caatcgtatg aatgcgctct ttgaatttta
      901 tgcggcgctt ttgacagata agcaaatgaa ttatatcgag ctctactacg ctgatgatta
      961 cagccttgct gaaattgccg aggagttcgg tgtcagtcgt caggctgtct atgacaatat
     1021 caagcgaaca gaaaagattc tggaagatta tgagatgaaa ttgcacatgt actcggacta
     1081 tattgtccgc agtcagattt ttgatcagat tttggagcgc tatcccaagg ataactttct
     1141 gcaggagcag atagaaattt taacaagcat tgataataga gaataagagg aagaaaaatg
     1201 gcatttgaaa gtttaacaga acgtttgcag aacgtcttta aaagtctacg taaaaaagga
     1261 aaaatctctg aatctgatgt ccaagaggca accaaagaaa ttcgcttggc cttgctcgag
     1321 gccgacgttg ccttgcctgt tgtaaaggac tttatcaaga aagttcgtga gcgtgcagtc
     1381 gggcatgagg tcattgatac acttaatcct gcgcaacaga ttattaaaat cgttgatgag
     1441 gaactgacag ctgttttagg ttctgatacg gtagaaatta tcaagtcacc taagattcct
     1501 acaatcatca tgatggttgg tttgcaggga gctggtaaaa caacttttgc aggtaagctg
     1561 gctaacaaac tcaagaagga agaaaatgcc cgtcctttga tgattgcggc ggatatttac
     1621 cgtcttgctg ccattgatca gctgaagaca ctgggacaac agattgatgt gccggttttc
     1681 gctcttggga cagaggttcc agctgttgag attgtacgtc aaggtttgga gcaagctcaa
     1741 actaatcata acgactatgt cttgattgat actgcgggtc gtttgcagat tgatgagctc
     1801 ctcatgaatg agcttcgtga tgtgaaagca ttggctcaac caaatgaaat cttgcttgtc
     1861 gttgatgcta tgattggtca ggaagcagcc aatgttgcgc gtgagtttaa tgctcagttg
     1921 gaagtgactg gggtcatcct taccaagatt gatggcgata ctcgtggtgg tgctgctctg
     1981 tctgttcgtc acattactgg aaaaccaatc aagttcactg gtacaggtga aaaaattaca
     2041 gatatcgaaa ccttccaccc agaccgtatg tctagccgta tccttggcat gggggatatg
     2101 ctcactttga ttgagaaagc ttctcaggaa tacgatgaac aaaaagccct tgaaatggct
     2161 gagaagatgc gcgaaaacac ctttgatttt aatgatttca tcgatcaatt agatcaggtg
     2221 caaaatatgg ggccgatgga agacttgctc aagatgattc caggtatggc caacaatcca
     2281 gcccttcaaa acatgaaggt ggatgaacgc cagattgctc gtaaacgtgc cattgtgtct
     2341 tcgatgacac ctgaagagcg tgaaaaccca gatttgttaa atccaagccg tcgccgtcgt
     2401 attgctgctg gttctggaaa tacattcgtc gaagtcaata aattcatcaa ggactttaac
     2461 caggctaaac agctcatgca gggtgttatg tctggggata tgaataaaat gatgaagcaa
     2521 atggggatta atccaaataa ccttcctaaa aatatgccaa atatgggagg aatggatatg
     2581 tctgcccttg aaggaatgat gggacaaggc ggtatgcctg acttatcagc tctcggagga
     2641 gcaggaatgc cagatatgag ccagatgttt ggtggcggtt tgaaaggtaa aattggtgaa
     2701 tttgccatga aacagtccat gaaacgtatg gctaacaaaa tgaagaaagc gaagaagaaa
     2761 cgcaagtaag acaagagatt gatgcaaatc tcatttgatg agaaaataaa gtaaaaattt
     2821 ctatgataaa acgtacagta tcaaggtttt agaatatctg atattatacg ttttttgatt
     2881 ttaataattt tgttaagaca cttttattat agtatacgaa aaatccactc agctgtctga
     2941 gtggattagg tgtatttaga ctcttagtct ttattttcgt atggcaagat caagttcaag
     3001 atgattcctg tcatggctga aagggcagta cctgaaagtg taactggacc aagtttaagg
     3061 atagctcctc caagtccaag aaccaacata gcacttgcga tgatgaggtt tcgcatttga
     3121 gcgaaatcaa cacgttcttt aatcaagact ttcaaaccat tgctggcgat aaccccatag
     3181 agaaggattg acataccacc aagtacagcg tttggaatag ttgaaatcaa ggcagtgaat
     3241 ttaccaagga agctgagggc aatcgcgatg aaggcagcgt tacggataac tgagacagaa
     3301 gcgatacgag tcataccgat aacccctgta ttttctccgt aagttgtatt ggctggtcca
     3361 ccaaggaagg cagaaacaga agttgcgata ccgtcaccaa taagagtacg gtgaagacct
     3421 ggttctttta agaattgacg gccacagatt tgacccaaaa cagtatggtc tccgatatgt
     3481 tcagaaattg ttacgatagc gattggcaag atagcgatgg cttctggacc aaagtaaaga
     3541 ttgtactctt taaaggcacc acctgtgcta aatggcaagt agaaaccagg aatttcaaac
     3601 cagttagctt ctaggacagg cgtaaagtca accaaaccaa gagttagtgc gaagaggtaa
     3661 ccaccgataa tggcaaagag gaatggaatg attcgtagga agccttttcc ttttgtattg
     3721 ataaaggcag caattaggaa agtaacaacg gctaccagag catttttcca atttccgtct
     3781 gctacaagac ctgcattggt aacagctgaa cctgcaagtc caagaccgat aacgatgatc
     3841 ataggaccga taatgattgg tggcaagagt ttatcaatcc attttgttcc tacaaatcgg
     3901 atgctggtag caacaaggac atagaccaaa ccagtcaaga taacccctgt ttgagcagca
     3961 gatacatccc cccccatttc tttcatagcc agtgacatag ctgtgataaa ggcgaatgaa
     4021 gaacctagat aaactggaac tttaaaacca gtagcaatca tgtagatgag tgttccaaca
     4081 cctgaagcaa aaagggcaac agatacaggc attcccaaaa tcaatggtac caagatggtc
     4141 gcaccaaaca tggcgaaaac gtgttggaaa ctaaggagaa ttccttttcc agccgaagga
     4201 cgttggtcaa cgtctagtaa caaatcaaca gttgattctt gtttcatata aacctcactt
     4261 ttgggcatca aaaaagagcc cattatttta cagcaatagg ccctcagagt aagacttctc
     4321 taaaatctag actttaaaga gtttcaaata tttttgcgtc ttcgtcacct cacgggatga
     4381 cattaaaaac ctttgcttag gatagtatag cagaaaaaaa tgattttgta aatcat
//
LOCUS       DAVKXA010000087         4394 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKXA010000087 DAVKXA010000000
VERSION     DAVKXA010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4394
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.087"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            116..253
                     /locus_tag="VW883_002055"
     CDS             116..253
                     /locus_tag="VW883_002055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275112.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSNHTHGKAALTWFEEI
                     F"
     gene            complement(578..775)
                     /locus_tag="VW883_002056"
     CDS             complement(578..775)
                     /locus_tag="VW883_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0275113.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(760..978)
                     /locus_tag="VW883_002057"
     CDS             complement(760..978)
                     /locus_tag="VW883_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0275114.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(1076..1861)
                     /locus_tag="VW883_002058"
     CDS             complement(1076..1861)
                     /locus_tag="VW883_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0275115.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESASS"
     gene            complement(1863..2681)
                     /locus_tag="VW883_002059"
     CDS             complement(1863..2681)
                     /locus_tag="VW883_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0275116.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2683..3675)
                     /locus_tag="VW883_002060"
     CDS             complement(2683..3675)
                     /locus_tag="VW883_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0275117.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
BASE COUNT         1487 a          930 c          750 g         1227 t
ORIGIN      
        1 ataattgtta tctctctata aaaacagtat atcatttaaa aaaatttaat tcaagaaaaa
       61 ttaacatgca ttaatttatt ttttagcaca cgttaaaaag taagattagt actcaatgaa
      121 aatcaaagag caaactagga aactagccgc aggttgctca aaacactgtt ttgaggttgt
      181 ggatagaact gacgaagtca gtaaccatac gcacggcaag gcggcgttga cgtggtttga
      241 agagattttc taagagtata agtccaaaac tttcgttaac cgggatacat tataagcaca
      301 ttcataccat caaaaatagt agcaataaac ttgaacaact accggaaaca cgaaaacagg
      361 cataattgat gaaatatcag cgctattaaa caatataaat aaccgctaag aataaggctt
      421 aacggttatc ttctacctat ctattttttc aactcctcag tcgtttatct acctataacc
      481 taggctttac gagtgccttg ctctaccaac tgagctaaat cggcgattac acttacagta
      541 tagcactctg agaataaaaa atagatgtca agtaatatta ttcaagcttt ttaatcaaaa
      601 tctgacaagg attttgcgga ttccatagtt gaggaaaaat ctctaacttt ttaaagccaa
      661 gacctcgata aaagtcattt gttcgatcat aatctttatt agaagcttct gccactgttt
      721 tgacctgcag ataaccaact tttttacgag cttcactctc taaagtagca agcaattggc
      781 tcccaatttt tctaccttga taagcttttt tacgccgaga caatcaatct ctgcacaatc
      841 ttcactcgaa taggataagc ttacaaatcc agtcaaatca ctctcctgat aggcggtcca
      901 aacttgcagt gtcgtggttc cttctatata ggtttgtgtg ctttctggga ttccaaacca
      961 ttctggcaaa tccttcaaaa tctcagcgac aactgccttt tttgattttc atccttgact
     1021 tcttcaatta caaacatcat aagttccttt cttgatttta gtcttacttt agcttttacg
     1081 aactcgcact ttcgtaggaa tctaagccct tatcccaaag tttaagggaa ataacaaaga
     1141 aaaccagaga aatcaacatc aaacctccta cgttaaagaa cacatccttt tcctgtaaga
     1201 aatagctagc tggatagtag gctgtaaagg cgaaaggcac gataaagcta atcaaccaac
     1261 gaagaagaga attgtaaata gaaatcggat acttagcaaa gtcattgaac atatagaaga
     1321 tgtaaatcat ggcgcctgac tgcttagtcc aaaaggcgat actggctgtt gcgattttaa
     1381 gagaagtata aatcaaggtc gcaaaaggaa tacaaactag gaaaagcaga aattttggaa
     1441 gagtccaaac aatgctggtc actgttgttc ccaataaaat accaccgact aagagttcac
     1501 ccaaggcatc aatctgaaag gtttcaacta ggatgtgaaa gagaggattg atgggacgag
     1561 tcagatactt gtcaaactct ccttttcgga ctaggcgttg ccctagtgcc cagagattgt
     1621 caaaaaagag atggtccatt cccttgggaa tcaaggaaaa tccataaatg aaagctatct
     1681 cttgaaaggt ccaaccttct aggaatggaa tatgttgaaa gatgacattg agaaacaaga
     1741 gattcaagcc ttgagccaga aagactccca agacaccaac cacaaaatcc accttatatt
     1801 ccatgatttg tttgatgtat tgtctgataa aaatcagatg cattcgttga tattttttca
     1861 tactaacctc cttgaatggt gataaaggac tggacccgtt tccaaatcaa ctgagacaat
     1921 cccaccatca ctaagagcca gaagaactgc aaaaggagtg cctgaagaat ctgactggca
     1981 tcgtattttc caacaatgat cataactgga gtataaatca aggatgaaaa aggcaaaaag
     2041 gaaagaatat ctgaaacaac ctttggaaag aatgccaagg gaatcaaact ccccgacata
     2101 aaagccacta tggaagtctt aagtaggttg gaaccccaaa gatttttaaa cacaaaggct
     2161 gaaaatccaa agcaaatatt aaagaaaaag ttaatcagat aggcgagcgt taagctaaaa
     2221 agataaagga cagttaatcc tagcacctct acaatacctt gacccgatat gattttcatc
     2281 aagacaatga cacttaaaaa tggaaggcca acgctgataa aaatcaacca cttggaacca
     2341 agctcggtga aaagatagga ggccgcaaaa tgcactggtc gcaacaaacg catgataatg
     2401 gagccatcct tgacctcctc cccaatcata aaggacgaat cggatctagt cagaagattg
     2461 gtcacaaaac tcatgatgat gtagagggtg atatccgcca tactgaagcc ctgaatcaaa
     2521 gactcttgcg aagaatcaaa gacagccttc cagagataaa aggccacaaa agcccccatg
     2581 acatcgccaa tccgatagag aataaagttg actcggtaag taatcaactc ctgaacccct
     2641 gcattgataa agggtttata acgtctccac aatttgatca tcctagagct cctttcggta
     2701 gaagcgacgg ataatatcct caatatccgt atccaccatc ttcaaatcgc ggatttcaaa
     2761 atcagacagg gtttgcttga taatgtcagc tgactggtag cgagaactat caaattcaat
     2821 gttgaggctg tttccttgtc tatcaatggt catatcagac agaccttcat agtgagagac
     2881 gagatgactt tgacctggta gcagttcaaa agagagagtc ttcatcttac caaaggtctc
     2941 cttgagttgg ctcaccgttc catcaaaaat ctcttgcccc ttgtcaatca tgaaaatccg
     3001 atcacaaagt tgctcaatat cactcaaatc gtgagtggtc aaaagaatgg tagtttcttc
     3061 ctcttgattg atctgagtaa ttgcccgacg aatattatcc ttaaccgaaa cgtccaaacc
     3121 aatggtcggc tcatctaaaa aaagaacctt gggattgtgg agcaaggagg ccgcaatatc
     3181 cgcccgcatc cgttgtccca gtgaaagagt ccgcacggga tccttgataa agtccttcaa
     3241 atccaagact tcattcaaaa agtccatacg cttatgaaag agcgagtctg gcacatcata
     3301 aatctctttt aagacagtgt aggtctcttg cagagccaaa tcccaccata gctgggtgcg
     3361 ttgtccaaag actacgccaa tatctttgac ataatcttgc cgattgtcct ggggaatctt
     3421 gccgttaatc cgacaaaaac cagatgttgg tttcaaaatt cctgtcagca ttttaatggt
     3481 tgtcgacttc ccagcaccat ttgccccgat aaatcctaaa atctgccctt ttggaacctc
     3541 aaaggtcaaa tccttgaccg cttcaaaggt ctgcttttca ggatgaataa aggagcgcaa
     3601 agcccccttc aagcccggtt ccttaacagt cttcacaaaa tttttctgaa gatgttccac
     3661 ttctatcatt gccatatcta tctccctatc gtaaggaata gcaacattgt gtttttaact
     3721 acaaatattc taaatccttg ctttctacac cttctacatt ttattactac aaaaggcttt
     3781 ataccaacct attatagtcc aataaaaaac gaaatgcaag agtttgccta tggattgtga
     3841 aattaggatt tctctcataa aataatactt ttaatcaaaa attctgttta atagtttaaa
     3901 ttaccaacct actcatcttc tcaccagagg gcggtattaa ctttgatcat aaaatcggat
     3961 actccctcta tccagaaaat atgctcagaa tgattgtctc taaacaatac ctgctctttt
     4021 acctcattca tgaaaaagaa gtccataccc tgagaattat caactcacgc atcgactacc
     4081 taaaccaact cgaccacctc tttcgtacat gtaggaaact attttcctca caaataatct
     4141 cattataaaa tccaataaat ttttttagct cacttgaata ttttctttgt atcgttttat
     4201 cagcttcaat ctgatctaga cttgttacct tggaacgact tgaaataacc tttataaaat
     4261 aacacttaag gctttcatca tctcgtataa atttttcaat agtgatataa aaagctttca
     4321 tattctgttt gtaatcagat atcaattgat taattttatc attctgatga agattcgata
     4381 ccataatata tagc
//
LOCUS       DAVKXA010000088         4293 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKXA010000088 DAVKXA010000000
VERSION     DAVKXA010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.088"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1..515
                     /locus_tag="VW883_002061"
                     /pseudo
     CDS             1..515
                     /locus_tag="VW883_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            443..895
                     /locus_tag="VW883_002062"
     CDS             443..895
                     /locus_tag="VW883_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275118.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDRPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1714..2073
                     /locus_tag="VW883_002063"
     CDS             1714..2073
                     /locus_tag="VW883_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275119.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            2083..2448
                     /locus_tag="VW883_002064"
     CDS             2083..2448
                     /locus_tag="VW883_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0275120.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYEQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            2435..>4293
                     /locus_tag="VW883_002065"
     CDS             2435..>4293
                     /locus_tag="VW883_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV0275121.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEMYNVNFSNNDKLYESRNDRQEKHQQTIHAHYLIQSFSPEDNLTPEEINR
                     IGYEIMMELTGGRFKFIVATHTDKDHVHNHILINAIDRNSDKKLIWNYALERNLRMIS
                     DRISKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLH
                     VQIDFSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKTYFAKQEIESRLKFLLKS
                     VYSLEELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYF
                     EDREVRDIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTD
                     NQIEKLVDDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNK
                     ENMDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTES
                     IMLDRLNTDILKLQQELGNEINKYEEIARRLDLFVKIINTNKFTVLKFHENALL"
BASE COUNT         1566 a          639 c          843 g         1245 t
ORIGIN      
        1 aaaagaatat attagttttc ttatgttagc agaggcaatc ataaaaaatg gaatagaaat
       61 agttgtagta actgatcata atactaccaa aggtattaaa aagttacaaa tggcagtctc
      121 aatcataatg aaaaattatc cgatttatga tatacatcct catattttac atggagtaga
      181 aattagtgca gcagataaat tgcatattgt atgtatatat gattatgaac aagaatcatg
      241 ggttaatcaa tggttaagtg aaaatattat aagtgagaaa gatggaagtt atcaacattc
      301 actgactata atgaaggatt tcaataatca aaaaatagtt aactatattg ctcatttcaa
      361 tagttatgac attttgaaaa aaggttctca cttatcaggt gcatataaac gaaaaatttt
      421 ttctaaagaa aatacacgat ttttggagtt taatattaac tcgaaagaat cttcgcaaca
      481 acttgatatt ctctataaag aagttggtgt attaagtttg ggacaaaaag ttgtagccat
      541 gcttgatttt ttattagcat atagtgatta ttctaaagac ttcagaccat tgattattga
      601 tcggcctgaa gacaatctag acaatcgtta tatttacagg catttagttc agcagtttag
      661 agatgtgaaa gctcaacgtc aaattatttt agcaacacat aatgctacaa ttgtaacaaa
      721 ttctatgaca gatcaagttg ttattatgga gtcagatgga gttaacggat ggattgaatc
      781 acagggatat gttagtgaaa aatatataaa aaatcatatc atcaatcaat tagagggagg
      841 aaaagattcc ttcaagcata aaatgtctat atatgagacg gctttatcag agtagagtca
      901 gaaaaagtag gttagaaatt tagcctactt ttttctttgt ccgacaggca tagtgtacat
      961 ctgaggtcca agtcctctgt ggatgtttgc tgcagatgaa accaatagcg actcctaagc
     1021 ctgaatatcg tgaggtaggg gggataggaa ggaattagcg aaatcaaggt tctacaaaca
     1081 gaatcgcgac ttgaagccat atatagcgga tgaggaactc taaaatccaa ataggtgtcg
     1141 taacctatat acgtaaatta cgagagtaaa ctaggaaaga tgtacggctt attccgtgag
     1201 cgtttaggac gtagtacaac gaatcatggg agtcagctga acacatagta ttgaagaaat
     1261 ttctgtaatg gaaatggagc gaagaagtga acgattaaat gaatacctct ctaattaaat
     1321 ttgtcaattc taattcctgg tatgaaaaga cagtgacctg aaaatgtaaa cgatgggagc
     1381 tgatcataaa tataggacgg tacatgcagt ggtgttagag attagtcctt acttgatttg
     1441 tgataacttc cccaaatttc ttctgctata cttttctcaa cttttaaaaa tccaactaag
     1501 aattttacct gggggtttgg gggcgaagcc accaagttat cttatcgttg gctgtcaaaa
     1561 ctggaaggtt ttggttagct ggcgatatga ttttttgggt attgtgatca caatgcctga
     1621 actcgcaaag accgaacaag gactttaaga aatttcccgt atgacacacg gggtcggggt
     1681 ttacccgaga aaggatgaaa gtgaggaaaa gagatgtctg aacagtaccg tgacattcga
     1741 aaagaggtaa atctaaccgc agatgagcta aaacagattg aaaaaatgat ggaggttgat
     1801 aattatcgtc acttttcacc attcgtcagg gataaaattt tgatgactga tgacaaacag
     1861 ttagctgcca aagaatggtt ttccctttgg cagtctcaaa agtttgaaca gatcagtcga
     1921 gatgtgcatt tggttttgat tatcgcaaga gagaatcacc aagtgactca agaacacgtg
     1981 tcaatcttat tgacctgcgt tcaagaattg attgcggaag tcaatcaagt acagtcactc
     2041 agtcgtgggt ttcgtgaaaa atacatgaga taggaggcta ctatggttta tcgttatcgt
     2101 accaatctca aaaaagtatt tctaacagat tcagaattac accaattgaa tgaacggatt
     2161 gctaagagca attgtcaaaa tttctcagtc tatgccagaa aagttttgct taatcccaat
     2221 atgtcatttg tcacgattaa cactgatact tatgaacagt tagtgtttga attgaggagg
     2281 attggaaata acatcaatca aattgcgcgt gcgattaatc aaagccatct gatttctcag
     2341 gaccaattac aagaattgag taaaggagtc ggagagttga tcaaggaagt ggacaaagaa
     2401 tttcaagtgg aagtgaaaag attgaaggag tttcatggta gtcactaagc attttgcgac
     2461 acacggaaaa aaatatcgta ggcgtttaat taagtatatc ctcaatcctg ataaaacgga
     2521 caatttgaaa ttagtatctg attttggcat gagcaattac ttggacttcc ctagtcatgc
     2581 agaaatggta gagatgtaca atgtcaactt cagcaataat gacaagttgt acgaatccag
     2641 aaacgaccga caagaaaaac accaacaaac tattcatgct cattacctca ttcaatcatt
     2701 ttctcctgaa gataatctga cacctgaaga aattaaccgc attggttatg agatcatgat
     2761 ggaattgaca ggaggtcgtt ttaagtttat cgtagcaact cacacagaca aagatcatgt
     2821 tcataatcac atcctaatca acgctattga ccgcaattca gataaaaagt tgatatggaa
     2881 ctatgccttg gaacgaaacc tccgtatgat ttcagaccgt atttctaaag tgactggtgc
     2941 aaaaattatt gagaaacgtt attcctatcg agattataaa aaatataggg aatctagtca
     3001 taagtttgaa ttgaaacaac gtctttattt tttgctacag caatctaaat cgtttgatga
     3061 ttttttagag aaagcaaagc agttgcatgt tcagattgat tttagtcaaa agcatagccg
     3121 ttttttgatg acagatagaa cgatgataaa accaattcga ggacgccaac tcagcaaacg
     3181 agatttatat gatgaagact tttttaaaac atattttgcc aaacaagaga ttgaaagtcg
     3241 tttaaaattt ttactaaagt ctgtttattc attagaagaa ttgcatgtaa aggctaaaga
     3301 gttgaatcta accatcgagt taaaacagaa aaatgtgatg tttaccctag aagaagatgg
     3361 caaaaagata agcctgagtc ataaaaaaat tagcgataag aaattgtacg atgttcaatt
     3421 ttttaatcgt tattttgaag atagagaagt tagagatatt caagcattag aaaatcttca
     3481 ggaagatttt cagacttttc gagaggagca gcataaggag aaagtctccg ctgaagaaat
     3541 cgaggaagcc ttcaagaaat acaaggaaaa acgagatgct atccatgagt ttgagattga
     3601 acttacggat aatcagatag agaagttggt tgatgatggt gtctatatac aggtttcgtt
     3661 tggtatcaaa cagagtggac tcatctttat tcctaactac cagctagata tttttgagga
     3721 agacaatcat aaaaaatata aagtctacat tcgagaaacg tcttcttact ttgtctataa
     3781 taaagaaaac atggataata attgtttcat caagggtagg accttaatca gacaattgag
     3841 caacgatagc caaaaactcc cctatagacg accaacttta aaaagtctta aagagaagat
     3901 ttctgaaatt aatcttatga ttgaactatc taacacgaac aaacaatacc aagaaatcaa
     3961 agatgagctt gtattagaaa ttgcagagat tgatatgcag ctagaagaaa cccaagaaaa
     4021 aatcgccacc ttaaacaaga tggcggaagt ccttatcaat ttgaagagtg aagatcatga
     4081 gactagaaaa ttagctaagt atgattttga ccaaatgaac atgacggaat caataatgtt
     4141 agatcgactc aatacggata ttttaaaatt acaacaggaa cttggtaatg aaattaataa
     4201 atatgaggag atagctagaa gattggattt gtttgtgaaa attattaata ccaataaatt
     4261 tacagttcta aaatttcacg agaatgcctt act
//
LOCUS       DAVKXA010000089         4264 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKXA010000089 DAVKXA010000000
VERSION     DAVKXA010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.089"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..812
                     /locus_tag="VW883_002066"
     CDS             <1..812
                     /locus_tag="VW883_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0275122.1"
                     /translation="SLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRV
                     KAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDL
                     LATVKYYVEHPNERPHSDNGFGNASDHVRKNKADQDSKPDEDKGHDEVSEPTHPESDE
                     KENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEK
                     VTDPSIRQNAMETLTSLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            1022..4141
                     /gene="phtE"
                     /locus_tag="VW883_002067"
     CDS             1022..4141
                     /gene="phtE"
                     /locus_tag="VW883_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0275123.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHRAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1572 a          713 c          843 g         1136 t
ORIGIN      
        1 atagtttgtc tgaagctgag agagcggcag cccaggctta tgctaaagag aaaggtttga
       61 cccctccttc gacagaccat caggattcag gaaatactga ggcaaaagga gcagaagcta
      121 tctacaaccg cgtgaaagca gctaagaagg tgccacttga tcgtatgcct tacaatcttc
      181 aatatactgt agaagtcaaa aacggtagtt taatcatacc tcattatgac cattaccata
      241 acatcaaatt tgagtggttt gacgaaggcc tttatgaggc acctaagggg tatactcttg
      301 aggatctttt ggcgactgtc aagtactatg tcgaacatcc aaacgaacgt ccgcattcag
      361 ataatggttt tggtaacgct agcgaccatg ttcgtaaaaa taaggcagac caagatagta
      421 aacctgatga agataaggga catgatgaag taagtgagcc aactcaccct gaatctgatg
      481 aaaaagagaa tcacgctggt ttaaatcctt cagcagataa tctttataaa ccaagcactg
      541 atacggaaga gacagaggaa gaagctgaag atactacaga tgaggctgaa attcctcaag
      601 tagagcattc tgttattaac gctaagatag cagatgcgga ggccttgcta gaaaaagtaa
      661 cagatcctag tattagacaa aatgctatgg agacattgac tagtctaaaa agtagtcttc
      721 ttctcggaac gaaagataat aacactattt cagcagaagt agatagtctc ttggctttgt
      781 taaaaaaaag tcaaccggct ccgatacagt agtaaaatga atggagcata ttttatggag
      841 aagtaacctt tcgtgttact tctctttttt agaaaaatgt aacagaaact tgacaaaagt
      901 aattttaaat agtaaactat ttactggtta attaaatggt taaataaccg gtttagaaaa
      961 ctatttaata aagtaaaaga agttgagaaa aaacttcatc atttattgaa atgagggatt
     1021 tatgaaattt agtaaaaaat atatagcagc tggatcagct gttatcgtat ccttgagtct
     1081 atgtgcctat gcactaaacc agcatcgttc gcaggaaaat aaggacaata atcgtgtctc
     1141 ttatgtggat ggcagccagt caagtcagaa aagtgaaaac ttgacaccag accaggttag
     1201 ccagaaagaa ggaattcagg ctgagcaaat tgtaatcaaa attacagatc agggctatgt
     1261 aacgtcacac ggtgaccact atcattacta taatgggaaa gttccttatg atgccctctt
     1321 tagtgaagaa ctcttgatga aggatccaaa ctatcaactt aaagacgctg atattgtcaa
     1381 tgaagtcaag ggtggttata tcatcaaggt cgatggaaaa tattatgtct acctgaaaga
     1441 tgcagctcat gctgataatg ttcgaactaa agatgaaatc aatcgtcaaa aacaagaaca
     1501 tgtcaaagat aatgagaagg ttaactctaa tgttgctgta gcaaggtctc agggacgata
     1561 tacgacaaat gatggttatg tctttaatcc agctgatatt atcgaagata cgggtaatgc
     1621 ttatatcgtt cctcatggag gtcactatca ctacattccc aaaagcgatt tatctgctag
     1681 tgaattagca gcagctaaag cacatcgggc tggaaaaaat atgcaaccga gtcagttaag
     1741 ctattcttca acagctagtg acaataacac gcaatctgta gcaaaaggat caactagcaa
     1801 gccagcaaat aaatctgaaa atctccagag tcttttgaag gaactctatg attcacctag
     1861 cgcccaacgt tacagtgaat cagatggcct ggtctttgac cctgctaaga ttatcagtcg
     1921 tacaccaaat ggagttgcga ttccgcatgg cgaccattac cactttattc cttacagcaa
     1981 gctttctgcc ttagaagaaa agattgccag aatggtgcct atcagtggaa ctggttctac
     2041 agtttctaca aatgcaaaac ctaatgaagt agtgtctagt ctaggcagtc tttcaagcaa
     2101 tccttcttct ttaacgacaa gtaaggagct ctcttcagca tctgatggtt atatttttaa
     2161 tccaaaagat atcgttgaag aaacggctac agcttatatt gtaagacatg gtgatcattt
     2221 ccattacatt ccaaaatcaa atcaaattgg gcaaccgact cttccaaaca atagtctagc
     2281 aacaccttct ccatctcttc caatcaatcc aggaacttca catgagaaac atgaagaaga
     2341 tggatacgga tttgatgcta atcgtattat cgctgaagat gaatcaggtt ttgtcatgag
     2401 tcacggagac cacaatcatt atttcttcaa gaaggacttg acagaagagc aaattaaggc
     2461 tgcgcaaaaa catttagagg aagttaaaac tagtcataat ggattagatt ctttgtcatc
     2521 tcatgaacag gattatccaa gtaatgccaa agaaatgaaa gatttagata aaaaaatcga
     2581 agaaaaaatt gctggcatta tgaaacaata tggtgtcaaa cgtgaaagta ttgtcgtgaa
     2641 taaagaaaaa aatgcgatta tttatccgca tggagatcac catcatgcag atccgattga
     2701 tgaacataaa ccggttggaa ttggtcattc tcacagtaac tatgaactgt ttaaacccga
     2761 agaaggagtt gctaaaaaag aagggaataa agtttatact ggagaagaat taacgaatgt
     2821 tgttaatttg ttaaaaaata gtacgtttaa taatcaaaac tttactctag ccaatggtca
     2881 aaaacgcgtt tcttttagtt ttccgcctga attggagaaa aaattaggta tcaatatgct
     2941 agtaaaatta ataacaccag atggaaaagt attggagaaa gtatctggta aagtatttgg
     3001 agaaggagta gggaatattg caaactttga attagatcaa ccttatttac caggacaaac
     3061 atttaagtat actatcgctt caaaagatta tccagaagta agttatgatg gtacatttac
     3121 agttccaacc tctttagctt acaaaatggc cagtcaaacg attttctatc ctttccatgc
     3181 aggggatact tatttaagag tgaaccctca atttgcagtg cctaaaggaa ctgatgcttt
     3241 agtcagagtg tttgatgaat ttcatggaaa tgcttattta gaaaataact ataaagttgg
     3301 tgaaatcaaa ttaccgattc cgaaattaaa ccaaggaaca accagaacgg ccggaaataa
     3361 aattcctgta accttcatgg caaatgctta tttggacaat caatcgactt atattgtgga
     3421 agtacctatc ttggaaaaag aaaatcaaac tgataaacca agtattctac cacaatttaa
     3481 aaggaataaa gcacaagaaa actcaaaact tgatgaaaag gtagaagaac caaagactag
     3541 tgagaaggta gaaaaagaaa aactttctga aactgggaat agtactagta attcaacgtt
     3601 agaagaagtt cctacagtgg atcctgtaca agaaaaagta gcaaaatttg ctgaaagtta
     3661 tgggatgaag ctagaaaatg tcttgtttaa tatggacgga acaattgaat tatatttacc
     3721 atcgggagaa gtcattaaaa agaatatggc agattttaca ggagaagcac ctcaaggaaa
     3781 tggtgaaaat aaaccatctg aaaatggaaa agtatctact ggaacagttg agaaccaacc
     3841 aacagaaaat aaaccagcag attctttacc agaggcacca aacgaaaaac ctgtaaaacc
     3901 agaaaactca acggataatg gaatgttgaa tccagaaggg aatgtgggga gtgaccctat
     3961 gttagatcca gcattagagg aagctccagc agtagatcct gtacaagaaa aattagaaaa
     4021 atttacagct agttacggat taggcttaga tagtgttata ttcaatatgg atggaacgat
     4081 tgaattaaga ttgccaagtg gagaagtgat aaaaaagaat ttatctgatc tcatagcgta
     4141 aggaatagca gtagaaaaag tctgaatcaa aaatgaagtt ctctcaaaag ttagaaataa
     4201 aactctgact ttgggagaat ttcattttat tattaatata taaaatttct tgacatacaa
     4261 ctta
//
LOCUS       DAVKXA010000090         4140 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKXA010000090 DAVKXA010000000
VERSION     DAVKXA010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.090"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            371..598
                     /locus_tag="VW883_002068"
     CDS             371..598
                     /locus_tag="VW883_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275124.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3768
                     /gene="nanA"
                     /locus_tag="VW883_002069"
     CDS             886..3768
                     /gene="nanA"
                     /locus_tag="VW883_002069"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0275125.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDKVVISNLRDNPEAKD
                     PAAPSPLNIDMVLVQDPTTKRIFSIYDMFPEGRAVFGMPKTPEKAYEKIGDKTYQILY
                     KQGESGHYTVRENGEVYNAQNQKTDYRVVVNPTEPGYRDKGNLYKGQELIGNIYFAHS
                     TKNPFRVANTSYLWMSYSDDDGKTWSAPRDITPGLRKDWMKFLGTGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1418 a          655 c          896 g         1171 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt ttgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattag gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg aaagacatgg ggagataagg tggttatctc caatcttcga
     2041 gataatcctg aagctaaaga tcctgctgcg ccatcgcctc taaatattga tatggttttg
     2101 gttcaagacc cgacaacaaa gagaatcttc tcaatttatg atatgttccc agaaggtcga
     2161 gcagtttttg gaatgccaaa aacacctgaa aaagcttatg aaaagatagg ggataaaact
     2221 tatcaaatct tgtataaaca aggagagtct ggtcattata ctgttcgtga gaatggagaa
     2281 gtgtataatg cacaaaatca aaagacggat tatcgtgttg tagtgaatcc aacagaacct
     2341 ggctatagag ataaaggaaa tctttacaaa ggtcaggaat tgattggaaa tatctatttt
     2401 gcacacagta caaaaaatcc atttagagta gccaatacga gctatctatg gatgtcatat
     2461 agtgacgatg atggtaaaac ttggtctgca ccgagagaca ttactccagg tcttcgcaag
     2521 gattggatga agttcctagg aacaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gttattggct tggagttcga ctcagaagta
     3301 ttggtcaaca aggctccaac ccttcaattg gcaaatggta aaacagcgac tttcctaacc
     3361 cagtatgata gcaagacctt gttatttgca gtagataagg aagatatcgg acaggaaatt
     3421 attggtatag ctaaaggaag catcgaaagt atgcataatc ttcctgtaaa tctagcaggt
     3481 gccagagttc ctggcggagt aaatggtagc aaagcagcgg tgcatgaagt tccagaattt
     3541 acagggggag ttaatggtac agagccagct gttcatgaaa tcgcagagta taagggatct
     3601 gattcgcttg taactcttac tacaaaagaa gattatactt acaaagctcc tcttgctcag
     3661 caggcacttc ctgaaacagg aaacaaggag agtgacctcc tagcttcact aggactaaca
     3721 gctttcttcc ttggtctgtt tacgctaggg aaaaagagag aacaataaga gaagaattct
     3781 aaacatttga ttttgtaaaa atagaaggag atagcaggtt ttcaagcctg ctatcttttt
     3841 ttgatgacat tcaagctgat acgaaatcat aagaggtatg aaactacttt cagggtagtc
     3901 tgttctataa aatatagtag attgaaataa gatgtgaaca actctaccag gaaagtcaaa
     3961 ttaatttata gaattatttt agcagtcaag gtgtactgtt atatattcaa tatattatat
     4021 gactattaac cttgtcttct cctaaaattg actttcttgt tttcttatct tgtccactcg
     4081 aaacaagtat tgtaagaatt tgattatttt tgaaagtact tttaatatac ttgatatagt
//
LOCUS       DAVKXA010000091         3504 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKXA010000091 DAVKXA010000000
VERSION     DAVKXA010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.091"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            505..1044
                     /locus_tag="VW883_002070"
     CDS             505..1044
                     /locus_tag="VW883_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275126.1"
                     /translation="MNSKKIVPKTKTHTFDDVIEQGYCHRLSRYVPDAVVGGSYKYDS
                     TDALPYAKKLKNTLYGQNLSVKYVASLLDMWDRACQLFHTVTGTCLADDIFTSKKIYS
                     ELYFYNTNTSDFITDEIIELVKEKHRSYSRKADEDSILSVEHEFEINPDIYYYVLGKL
                     GWKRVKHNYLVKALAGALS"
     gene            1103..1333
                     /locus_tag="VW883_002071"
     CDS             1103..1333
                     /locus_tag="VW883_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275127.1"
                     /translation="MKNLYKYLFYLFFIGFGCTLYYVLLLKNVYSPIFEAIAILMGIT
                     MIIFLMIFIDMASPAGEERKHENVESKNLGDE"
     gene            1296..2657
                     /locus_tag="VW883_002072"
     CDS             1296..2657
                     /locus_tag="VW883_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV0275128.1"
                     /translation="MRMLNQRISVMNKYPYFIRPRNIKIVRLAIQIFTLLLLMCSWIA
                     TIPFIARLVFSMFFISLLFLVERFFRSNFMANLRDKLNIREALFYMLISLNLYDEIDN
                     EVVDTAVLYFDVEDNKVIVCVPLFGNRYLKTLKNLEEYLCPTLGLSLLSKKEEIDKTI
                     YVLGHVVQIEQYVFNSNTLKREFFEDIPNPIIKLSNTQQFSLKSNTNIGIYGRTGTGK
                     TIALQWYLFNALAKGCGTNDNTYLGIVDGKAADLFALGKLLQEDLGEQIAVGSSPQML
                     AKLSREFVEIMNERFEIIKQNSSLNADAYDLGMTPNFLFVDELASIRDSCGSSKQGGK
                     ELWNEILQNLGLIARKGRQAGCHLCLSTQDPNAENIPVELRSQISAVLYLGGPGADRL
                     KMAFSMCELENVPTVSDRKGEALFYADGLNTVEPVLTIVPFVDLKTKQEFLQVVRNIL
                     PNY"
     gene            2755..3069
                     /locus_tag="VW883_002073"
     CDS             2755..3069
                     /locus_tag="VW883_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275129.1"
                     /translation="MKLNDFLKPELLGNRFFAVKGYTEVLDRETNKPVALRLNVSIQD
                     ENSDFFMEMIQVKINTLSPTASVQEMANNKTCPVSLKDLNVGQFNGNLWFACSDVLPV
                     TK"
     gene            3103..3492
                     /locus_tag="VW883_002074"
     CDS             3103..3492
                     /locus_tag="VW883_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275130.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKDLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
BASE COUNT         1195 a          528 c          649 g         1132 t
ORIGIN      
        1 tctactacaa taacaaaatt atttgcttta tctactgttg tcatattgtt cctccatcta
       61 accattatag catcgcaaat cttttttgtc tactttttta aaataaacgg tctatttaaa
      121 aatattagac aaaaagaccg tatttttctt gacatagtgg atacgatatg ctaagatatc
      181 atcaacaggt aaataattac ctcaaacacc gtgtagaaag gaaaatttgt catgacccca
      241 gaagaacaaa tggcattaga gtatttttat gaagagatgg acgcctatta ttgtgaggaa
      301 gaacaaggag agatttttga ttgatacgag aattaaatca tatctatagt ttctcaggat
      361 aattggaaac tatatttgca agatactaca tttatacaca aaacacaaaa aggagaagat
      421 aaatgaatat tgcaagagcc tcacccagag tagagactaa ttgaaacaat gatacatata
      481 ttaattttga aaggaaatat tgttatgaat tcaaaaaaaa tagttccaaa aactaaaact
      541 catacctttg acgatgttat cgaacaaggg tattgtcata ggctatcaag atatgttcct
      601 gatgcagttg ttggaggttc ctacaaatat gattcaacag atgcattacc atatgcgaaa
      661 aaacttaaaa atacactata tgggcaaaat ttatctgtta agtatgtagc aagtttgttg
      721 gatatgtggg atagagcatg tcagttattt catacggtaa cagggacatg cttagcggat
      781 gacatcttta cctcaaagaa aatttatagt gaattgtatt tttacaatac taatacttct
      841 gattttatta cagatgagat tattgaactt gttaaagaaa aacatcgttc atattctaga
      901 aaagctgatg aagatagcat tttatcagtt gagcatgagt ttgagattaa ccctgacatc
      961 tattattatg ttctaggcaa attgggttgg aaaagagtaa aacacaatta cctagttaag
     1021 gctcttgcag gggcattatc ttagtttaat ctaggggagt attcctcccc ttttatatct
     1081 taaaaaagaa aggaattgcg tcatgaagaa tctctataaa tatctttttt atttgttctt
     1141 tattggattt ggttgcacat tatattatgt gcttctttta aaaaatgtct attctcctat
     1201 ctttgaagct attgcaatat tgatgggtat tacgatgatt atctttttga tgatttttat
     1261 agatatggct tcccctgctg gagaggagag aaaacatgag aatgttgaat caaagaatct
     1321 cggtgatgaa taagtatccg tactttattc gtcctcgaaa tattaaaatt gttagactag
     1381 ctattcaaat ttttaccctt ttacttctca tgtgttcatg gattgctaca atcccattta
     1441 ttgcacgtct agtcttttcc atgtttttta taagtcttct ttttttagta gagaggttct
     1501 ttcgttctaa ttttatggca aatttaagag ataaactcaa tatcagagaa gcattgtttt
     1561 atatgctaat tagtttaaat ttgtatgatg aaatagataa tgaagtagta gatacagcag
     1621 ttctatattt tgacgttgag gataataaag ttattgtctg tgtcccacta tttgggaatc
     1681 gttatctgaa aaccttgaaa aatttagagg aatatctatg ccctacgttg ggcttgtcct
     1741 tgctgtctaa aaaagaagaa atagacaaaa caatatatgt gttaggtcac gtagttcaaa
     1801 ttgagcaata cgtcttcaat agtaatacat taaaaagaga attttttgaa gatattccta
     1861 atccgataat taaattatct aacacccagc aattcagctt gaaatcaaac accaacatag
     1921 gtatatatgg acgaactgga acaggcaaaa caatagcctt acaatggtac ttatttaatg
     1981 cactagctaa aggttgtggc actaatgata atacttacct aggaatagtg gacggtaagg
     2041 cagcggattt atttgcactt ggaaaacttc tccaagaaga cttaggggag caaatagcag
     2101 tcggctcttc acctcaaatg ttagcaaaat tatcaagaga atttgttgag attatgaatg
     2161 aacgttttga aattatcaaa cagaatagtt cattaaatgc tgatgcttat gatttaggga
     2221 tgacaccaaa ttttctattt gtagatgaac ttgcttccat ccgcgatagc tgtggttcta
     2281 gcaaacaggg gggtaaagaa ctatggaatg aaattttgca aaacttaggc ttgattgcac
     2341 gtaaagggcg gcaggcaggt tgtcacctct gccttagtac ccaagaccct aatgctgaga
     2401 atattccagt cgaattgcgc tcccaaatat cggcagtttt ataccttgga ggcccagggg
     2461 ctgatagatt gaagatggct tttagcatgt gcgaattaga aaacgttcct acagtttcag
     2521 atagaaaagg ggaggctctc ttttatgctg atgggcttaa tacagtagag ccagtgctaa
     2581 caattgtgcc atttgttgat ttaaaaacta aacaagaatt tttacaggta gttagaaata
     2641 tactgccaaa ctactaataa cggtattttt ctctgttgga ataggaattc ttttcaacag
     2701 agaaaaagag ccaaccgact gcattgcagg aggtaagaaa gaaaggaatt tatcatgaaa
     2761 ttaaatgatt ttttaaaacc tgagctacta ggcaatcgct tctttgccgt gaaagggtat
     2821 acagaagtat tagatagaga gactaataag cccgtagctt tacgacttaa tgtgtcaatt
     2881 caagatgaga attctgattt ctttatggag atgatacaag tcaaaataaa tacattatcg
     2941 cctactgctt ctgttcaaga gatggcgaac aacaaaactt gtcctgttag tcttaaagat
     3001 ttaaacgtag ggcaattcaa tggaaatttg tggttcgctt gttctgatgt tttacctgta
     3061 acaaaatagc taagattaga taatatataa aggagtttta caatgcaaac ttttaactac
     3121 gatgatttta agaatgaaaa ggggattgtt tcattttctg aagcagaaca aatctattct
     3181 agtctcctta attcctccaa tcaacttgat aaagaatttc aagaagaatg gacaacattt
     3241 gtacttctat gcgtagagta tgcctctgca cgtggtaaat ggctcacact ctcaagagaa
     3301 gagaaacttg ccaatgatga atctagaact gttactcaca ataaagttat ttatcaacta
     3361 aagattttaa aagatttagc aagtgaacag ggcaatgatg ttgcttggtt tgaacaattt
     3421 aacgatgaca gaaaacgtat tggcgacttt gcttgctatg tagcttatat ctatgcctta
     3481 aatgctcgat agacaattag agga
//
LOCUS       DAVKXA010000092         3184 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKXA010000092 DAVKXA010000000
VERSION     DAVKXA010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3184
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.092"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            315..1601
                     /locus_tag="VW883_002075"
     CDS             315..1601
                     /locus_tag="VW883_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0275131.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1616..1927
                     /locus_tag="VW883_002076"
     CDS             1616..1927
                     /locus_tag="VW883_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275132.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            2187..2915
                     /locus_tag="VW883_002077"
                     /pseudo
     CDS             2187..2915
                     /locus_tag="VW883_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
BASE COUNT          991 a          546 c          686 g          961 t
ORIGIN      
        1 taataaataa aaaagcgata ttctagactg tatcaatcct tttccattat aggagcaaca
       61 gagtgggagt agtcatctaa ggactaattt atgtattttt acgagtcagt atcttgggat
      121 actggttttt acttttctag actttttgac tacttgttaa aactgggata attttcgact
      181 gtttaacagt tattatgcaa agtctaaaag attagaattg tcaaaacaat ccgtctaggc
      241 ttgattttat cctttattta ctataaaatg agaaggaaaa atgtcaaact tttatattgc
      301 aaataggaga aatcatgaca aaaacattaa aacgtcctga ggttttatca cctgcaggga
      361 ctttagagaa gctaaaggta gctgttcagt atggagcaga tgctgttttt atcggtggtc
      421 aggcctatgg tcttcgtagc cgtgcgggaa actttacttt cgaacagatg gaagaaggcg
      481 tgcagtttgc ggccaagtat ggtgccaagg tctatgtagc ggctaatatg gttatgcacg
      541 aaggaaatga agctggtgct ggtgagtggt tccgtaaact gcgtgatatc gggattgcag
      601 cagttatcgt atctgaccca gccttgatta tgattgcagc gactgaagca ccaggccttg
      661 aaatccacct ttctacccaa gccagtgcca ctaactatga aacccttgag ttctggaaag
      721 agctaggctt gactcgtgtc gttttagcgc gtgaggtttc aatggaagaa ttagctgaga
      781 tccgcaaacg tacagatgtt gaaattgaag cctttgtcca tggagctatg tgtatttcat
      841 actctggacg ttgtactctt tcaaaccaca tgagtatgcg tgatgccaac cgtggtggat
      901 gttctcagtc atgccgttgg aaatacgacc tttacgatat gccatttggg aaagaacgta
      961 agagtttgca gggtgagatt ccagaagaat tttcaatgtc agccgttgac atgtctatga
     1021 ttgaccacat tccagatatg attgaaaatg gtgtggacag tctaaaaatc gaaggacgta
     1081 tgaagtctat tcactacgta tcaacagtaa ccaactgcta caaggcggct gtggatgcct
     1141 atcttgaaag tcctgaaaag tttgaagcta tcaaacaaga cttggtggac gagatgtgga
     1201 aggttgccca acgtgaattg gcaacaggtt tctactacgg tataccatct gaaaatgagc
     1261 agttgtttgg tgctcgccgt aaaattcctg agtacaagtt tgtcgctgaa gtggtttctt
     1321 atgatgatgc ggtacaaaca gcaaccattc gtcaacgaaa cgtcattaac gaaggggacc
     1381 aagttgagtt ttatggtcca ggtttccgtc attttgaaac ctatattgaa gatttgcatg
     1441 atgccaaagg caataaaatc gaccgcgctc caaatccaat ggaactattg actattaaag
     1501 tcccacaacc cgttcaatca ggagacatgg ttcgtgcatt aaaagaagga ctcatcaatt
     1561 tttataagga agatggaacc agcgtcacag ttcgagctta agaaaggaaa aggaaatgat
     1621 agaggcacag ggtttcttag tggataagca aacaagatgc attcattacc atagcaagct
     1681 ggatattatt gctttacaat gctatgattg taaaaagtat tatgcttgtt atcggtgtca
     1741 tgattcatta gaaaatcacc cttttgagcc ttatccctta tctttgatac aggataagcc
     1801 tattttatgt ggtgtttgtc taaaactatt aacatataag caatataaag aaagcttaag
     1861 ttgcctcttt tgtttttctc gctttaatcc aggttgccaa aatcataagg aacgctattt
     1921 taaatagcaa atcatctagt tttgaagtag gagaaaactc aattccaaga gaaaatgaag
     1981 taaatcttcc cacaataaaa cgcataatat caagattgtt caatacctga tactatgcgt
     2041 ttttaagatt ttaaagactt ttttcctagc ccctttttac tttatctggt attttgacta
     2101 cttgttaaaa ctggggtaat tttcgactgt ttaacagtta ttatgcaaag tctaaaaggt
     2161 tagaattgtc aaaacaatcc gtctagagta tgcgtgatgc caaccgtggt ggatgttctc
     2221 agtcatgccg ttggaagtac gacctttacg atatgccatt tgggaaagaa cgtaagagtt
     2281 tgcagggtga gattccagaa gaattttcaa tgtcagctgt tgatatgtct atgattgacc
     2341 atatctcaga tatgattgaa aatggtgtgg acagtctaaa aatcgaagga cgtatggagt
     2401 ctattcacta tgtattaaca gtaaccaact gctacaaggc ggctgtggat gcctatcttg
     2461 aaagtcctga aaagtttgaa gctatcaaac aagacttggt ggacgagatg tggaaggttg
     2521 cccaacgtga actggctaca ggattttact atggtacacc atctgaaaat gagcagttgt
     2581 ttggtgctcg tcgtaaaatc cctgagtaca agtttgtcgc tgaagtggtt tcttatgatg
     2641 atgcggcaca aacagcaact attcgtcaac gaaacgtcat taacgaaggg gaccaagttg
     2701 agttttatgg tccaggtttc cgtcattttg aaacctatat tgaagatttg catgatgcca
     2761 aaggcaataa aatcgaccgc gctccaaatc caatggaact attgactatt aaggtgcctc
     2821 aacctgttca agctggagac atggttcgtg cattaaaaga aggactcatc aatctttata
     2881 aggaagatgg aaccagcgtc acagttcgtg cttaatgtag ttgtttagtt ttaaaaaatt
     2941 atgcaaagct ccatatacaa cacttaaacg agattaaaga atggcgaaat cccttgatgc
     3001 gcaagagatt agctgtcctt ttttattttt taagtgataa agtcggagct taggtatcaa
     3061 agcctatcaa attaaacaaa gaagtgatgt cttagatatt ttgaaaaaaa ttaataagca
     3121 gaaaactctc tattattttg ttgtagagag ttttttgtta ataaaatttt acaaaatgac
     3181 attt
//
LOCUS       DAVKXA010000093         3152 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKXA010000093 DAVKXA010000000
VERSION     DAVKXA010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.093"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..346)
                     /locus_tag="VW883_002078"
     CDS             complement(<1..346)
                     /locus_tag="VW883_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275133.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYE"
     gene            complement(404..1117)
                     /locus_tag="VW883_002079"
     CDS             complement(404..1117)
                     /locus_tag="VW883_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0275134.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1575..1955)
                     /locus_tag="VW883_002080"
                     /pseudo
     CDS             complement(1575..1955)
                     /locus_tag="VW883_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(2377..>3152)
                     /gene="phtB"
                     /locus_tag="VW883_002081"
     CDS             complement(2377..>3152)
                     /gene="phtB"
                     /locus_tag="VW883_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV0275135.1"
                     /translation="SLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRV
                     KAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDL
                     LATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEET
                     PREEKPQSEKPESPKPTEEPEEESPEESEEPQVETEKVKEKLREAEDLLGKIQNPIIK
                     SNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          940 a          629 c          521 g         1062 t
ORIGIN      
        1 gttcgtaggc atattttgct acatgatcta ggtatatatc aaaaaagtca tgaggaaaat
       61 ctcccataca gccattacga ttcatattga ggctatattt tcgattagta agataattcg
      121 gaaatatatt tcctattact ctaagattat ctacttgtga atcccttctc ccaatataat
      181 ccccttcttt gactaatgat ggagatttcc aagtaaaaat taaatcgcca gagaaatttt
      241 tcttatcaaa aaacttaaaa agagattgat aaatactatt tgctaattga caagtgtcag
      301 atgtaaattc ataattaaca gcttcattaa aatcaacttc agacatttca atgtactctt
      361 caatagtaat attagctttt ttgtagtcat tagctcgtct cctttaaaat gtgatctttt
      421 caagaatatt tttatctaaa caatccagca agtcttggta agaatagact tcgtaagtcg
      481 gctgggcttg tgtgtgattt tcgaggtgat gaggattata ccagatagtg tcaatccccg
      541 cattattgcc accttgaatg tcggcggtta gagaatctcc aatcatcagc gtcttttctt
      601 tactaaatcc agcaatttgc tggccaatct tttcataaaa aagagcatcc ggcttttgag
      661 tttgcaactg ttctgagata aagacttgat tgaaataagg tgctagacca gattgagcca
      721 aacgtcctgt ctgaatggca gtaatgccat ttgtcgcagc atacaagtca taatcacgct
      781 caatgaggct gtccaagaga tcatgagcgc ccgatagtgt ttgtccctgc tgagcgagat
      841 aaaattggta acgctgggca agaaaactac cgtctttttc ctgtccaaaa tgagaaaata
      901 aacgagaaaa gcgcgtgtta accagctctt gtttactgat tttcttcagc tccaagtctt
      961 tccagagagc cttgttcata ggaacgtaat aatctttata agcctgaata tccgcaactc
     1021 cttcttcttt tagaagttgg gtcaaagcca catcctcagc agcatcaaaa tcaagaagag
     1081 tgtggtcgag gtcgaagagt agaaatttgt agaacaattt gaggttttcc tttctgaaaa
     1141 ttcattaaga acattatatc ataaagcacc tcatacaatt aactaattta atcacttaaa
     1201 aaaattcgaa cactttctat acaactgaca gctcaaatct ttcagaatag aacaatacta
     1261 actatcgagc accccgtatt cataaatata tgtgtaattc tagacctaga attcctataa
     1321 actaaatgct ttcatactct tccaagtaat tgattgcctt aaattttaat ttttgaaggt
     1381 ttctaaagct agaatagccc catcacaatc agttttgatt gattcacaat ttagaaacac
     1441 tatagtttca ctcctgttaa aataaaaagg aactgcataa agcaatccct ttctgatttt
     1501 gaaatcattt acttaacatt ttatagttga gataatcaat agcttaccta taaaaagagt
     1561 tatagtaaaa ttccttattt attgatttca agctccgcta actgtgtttg aataactgac
     1621 agttctgcac cagcctgaag aagagcagct gcattatagg caccttctac aattggaacc
     1681 ctgttgatga tgatactttt atcactgaaa tcagtcacca tttttaagtt cattttagca
     1741 gaacctaggt caaaaaaggc aagtaaagta tctgctgtat tttcggaaac aaccctatct
     1801 acttaatcaa aactcgttcc aattcctccg ccctcggttc ctcctacata agtaatcgga
     1861 acatctttag ctactttact aatcagttca acaacacctt ctgcaatgtg tttggaatgt
     1921 gaaacgataa caagaccaat accaatactt tccatcaaac caccccagtt tctaaaatag
     1981 cagtaaagag taatcctgat gagaatgatc caggatcaat atgtccaaga aaccacatgc
     2041 tcctaagaca agagctaaca gactggccat caataatagt attgttcttt ttttcatcat
     2101 tactccttaa ctagtgttta actgatcaat tagccagtaa atagtttatc tttatttaca
     2161 ctatctgtta agatatagta aaatgaaata agaacaggac agtcaaatcg atttctaaca
     2221 atgttttaga agtagaggta tactattcta gtttcaatct actatatttt gcacattttc
     2281 atgaaaaaaa tgagaactag aactcacatt ctgctctcat ttttcgtttt cccgttctcc
     2341 tatcctgttt ttaggagtta gaaaatgctg ctacctttac ttactctcct ttaataaagc
     2401 caatagtttt tcagcttctg ccataatagt attgttgtcc tgggtgccaa atagtaaatt
     2461 attttttaat cctgtgagag tctctttggc attggacttg ataattggat tctggatttt
     2521 tccaagtaaa tcttcagcct ctctcagttt ttctttaacc ttttcagtct cgacctgagg
     2581 ttcttctgat tcctctggtg attcttcttc tggttcctct gttggttttg gagactctgg
     2641 tttctcgctt tgcggtttct cttctcgagg ggtttcttcc tcaggttttt ctgtctgagg
     2701 tttctcctcg tttggttttt ccgtttgatt ggtatcagct tgaccatttt tgtttctttg
     2761 aacgtggtcg ctagcgttac caaaaccatt atctgaatgc ggacgttcgt ttggatgttc
     2821 gacatagtac ttgacagtcg ccaaaagatc ctcaagagta taccccttag gtgcctcata
     2881 aaggccttcg tcaaaccact caaatttgat gttatggtaa tggtcataat gaggtatgat
     2941 taaactaccg tttttgactt ctacagtata ttgaagattg taaggcatac gatcaagtgg
     3001 caccttctta gctgctttca cgcggttgta gatagcttct gctccttttg cctcagtatt
     3061 tcctgaatcc tgatggtctg tcgaaggagg cgtcaaacct ttctctttag cataagcctg
     3121 ggctgccgct ctctcagctt cagacaaact at
//
LOCUS       DAVKXA010000094         3065 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKXA010000094 DAVKXA010000000
VERSION     DAVKXA010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.094"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            11..1180
                     /locus_tag="VW883_002082"
     CDS             11..1180
                     /locus_tag="VW883_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007555271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HEV0275136.1"
                     /translation="MSLSKQDAIKKAFGDGKAVFKYKNKDSIQDFITKNSDNPLLSGQ
                     YLDIYYAFTWSKHNDLIKEYSDMCKRIFSLSGVISFNQGIVSLGRPWIFPKLFSLLNG
                     NFKLSGEASYEEYENDIKSSFYQDICISDILELSYTQVLEIQNQIAEEFGIADISNIK
                     QFVADKQEREFREFVEQEFGITKVSEVLSFISQRNDKKVQELVTDNALVPTIFEYILA
                     IAWYYISDKKFQLRKSMQLTFSADNLPLSHAGGNKGDIEIEYSDKMLLLEATLMDKST
                     QKRGELEPVIRHSVNLALSTNKPLQTIFVANEVDDNVVNIFRATSFIQLNGTLTKGSV
                     KGLNIFALTIPEIINILDRKINEQRIFEKLDDFSTIEPYRIENGWREEIVSEILA"
     gene            1248..>3065
                     /locus_tag="VW883_002083"
     CDS             1248..>3065
                     /locus_tag="VW883_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEV0275137.1"
                     /translation="MIQRGSEFRKWDLHIHSPYTVLNNQFDKLPDGSPDVEKFIQKIK
                     DEGISAVGLTNYFRFSDDDFKLKDRLNEEGIATFLNLEVRLSNINKSDELFDYHVVFG
                     NEVQDDIVKNLLGHLKANIGDDEKSFNRLSKTEIEDKAHIPFKDLLKVLNSDRELNGR
                     FLTGFLSRGHGSATSDSDSKNKAVYEDICINSDFLIHSSNEVNITKDREFWLDKSPHI
                     RPLLQSSDSHSLEQIGSKYSWVKADLTFDGLEQIKYEPEYRISVEKEKPTLKKDELVI
                     DKILYNGQDIYLSENLNTIIGGRSTGKSTLLNSIAKKLGRELNGDSYYFENMDDFQII
                     WKDQQEDNSRQIEYIPQEYMFALARDNKKLKDLVGSIIQSKEMNSELKKYEQNCATLH
                     LEIRGLLDSYKENQKNIHELIKPEAEKQATQNRIKTYETKKKELLNASEITEQERDLF
                     ENKNKELQLLKTQKEIHESDLRYVSSILPITFEVESLPTTTTPSQDLRVKIGQITARL
                     RDSVRAQQEHEIRIIKLEKESLIKAIENKISDIGNDDIYKKCVEAMKNNSEIARLNSL
                     IKNEVDILAKIEAFEKQRDEFDKVTEEIQKEIISKYKEYS"
BASE COUNT         1167 a          375 c          565 g          958 t
ORIGIN      
        1 tgaagaaatg atgagtcttt ctaaacaaga tgctattaag aaagcttttg gagatggtaa
       61 ggctgttttc aagtataaaa ataaagattc tattcaagat tttataacta aaaacagtga
      121 taatccattg ctatcaggtc aatatttgga tatatattat gcatttacat ggtctaagca
      181 taatgatttg attaaagaat acagtgatat gtgtaaaaga atattttctt tgtctggagt
      241 aatcagtttt aatcaaggaa ttgtatcgct tggtcgacct tggatttttc ctaaactttt
      301 ctctttatta aatggtaatt ttaagctttc tggggaagca agctatgaag agtatgagaa
      361 cgatataaag agttcttttt atcaagatat ctgtatatcg gatattttag aattatctta
      421 tacgcaagtt ttagaaatac aaaatcagat tgccgaagaa ttcggcattg ctgatatttc
      481 aaatattaaa caatttgtag cagacaaaca ggaaagagag tttagggaat ttgttgaaca
      541 agaatttggt atcactaaag tatctgaagt tttgagtttt atttctcaaa gaaatgataa
      601 gaaagttcaa gaacttgtta cggataatgc cttagttcct actattttcg aatatatatt
      661 ggccattgca tggtattata tatcagataa gaagtttcaa cttagaaaat ccatgcagtt
      721 gacattttct gctgataacc tcccactatc acatgctgga ggcaataaag gagatatcga
      781 gattgaatat agcgataaaa tgcttttact tgaagcgaca ttaatggata aatcaactca
      841 aaaacgtggt gaattagagc cagttatacg tcattctgta aatttagcat tatctactaa
      901 taaaccgtta caaacaatat ttgtagctaa tgaagtagat gataatgtgg ttaatatttt
      961 tagggctaca tcgtttattc agctaaatgg aacattaacg aaaggtagcg taaaagggct
     1021 aaatatcttt gctttgacaa ttccagaaat tataaatatt ttggatagaa agattaacga
     1081 gcagagaatt ttcgaaaaat tagatgattt ttctactatc gaaccttata ggatagaaaa
     1141 tggatggcgt gaagagatag tatctgaaat tttagcatag cctgtaggaa atgcgagtaa
     1201 ttatagaggt ttgtataaga caattgatgt agaaaggttt gtattcaatg attcaaagag
     1261 gttcagagtt tagaaaatgg gatttacata ttcattctcc ctatacagtg ttaaataatc
     1321 agtttgataa gctgcctgat ggaagtccag atgtagaaaa attcattcaa aagataaagg
     1381 acgaaggtat ttctgctgtt ggattgacca attatttcag atttagtgat gatgacttta
     1441 agttaaaaga taggttaaat gaagaaggaa ttgcaacttt tttaaatctt gaggttagat
     1501 tatcaaacat taataaatca gatgaacttt ttgactatca tgtagtattt ggaaatgaag
     1561 ttcaagatga tatagtaaaa aatttacttg gtcatttaaa ggctaatatt ggtgatgatg
     1621 aaaaatcatt taatcgttta agtaaaactg agatagaaga taaggctcat attcctttta
     1681 aagatttatt aaaagtctta aatagcgata gagaacttaa tggtcgtttt ctaactggct
     1741 ttctttcgag aggtcacggt agtgcaacta gtgattctga ttctaaaaat aaggcagttt
     1801 atgaagatat ttgtatcaat tctgattttt tgattcattc tagtaatgaa gtaaatatca
     1861 caaaagatag agaattttgg cttgataaat ccccgcatat aagaccacta cttcaatcct
     1921 cagattctca ctctttggag caaataggaa gtaaatattc ttgggtaaaa gcagatttaa
     1981 cttttgatgg tctagaacaa ataaagtatg aaccagaata tcgcattagt gttgagaaag
     2041 aaaaaccaac tctcaaaaag gatgaacttg tcattgataa gattctatat aacggtcaag
     2101 atatttatct atccgaaaat ctaaatacaa ttattggtgg tcgctcaact ggtaaatcaa
     2161 ctctactaaa ttctatagct aaaaagctgg gacgagagct gaatggtgat tcatattatt
     2221 ttgaaaatat ggatgatttt caaattattt ggaaagacca gcaagaagat aattccagac
     2281 agatagagta tatacctcaa gagtatatgt ttgctttagc cagagacaat aagaagctta
     2341 aagatttggt aggaagtatt attcaatcca aagaaatgaa ctctgaatta aagaaatatg
     2401 agcaaaattg cgctactcta catcttgaaa ttagagggtt acttgatagt tataaagaga
     2461 accaaaaaaa cattcatgag ctaattaagc cagaagcaga aaaacaagct actcaaaatc
     2521 gaataaaaac atacgaaact aagaaaaaag aattattaaa tgctagtgag ataacggagc
     2581 aagaaagaga tttatttgaa aataaaaaca aagaattgca gttattgaaa acacaaaaag
     2641 agattcatga atctgacttg cgatatgtat caagtattct tccaattaca tttgaggttg
     2701 aaagtttgcc cacaacgact actccgtctc aagatttaag ggttaaaatt ggtcagatta
     2761 cagctcggtt gcgtgattcc gtcagagcac aacaggaaca tgaaattagg ataattaagt
     2821 tagaaaaaga aagtctaatc aaagctattg aaaataaaat ttcggacata ggaaatgatg
     2881 acatatacaa gaaatgtgtt gaggcaatga aaaataattc agagatagcg aggttaaatt
     2941 ctttaattaa gaatgaagtt gatattttag ctaaaattga agcgtttgaa aaacaaaggg
     3001 atgaattcga taaagtaaca gaagaaattc aaaaagagat tatttcgaaa tataaggaat
     3061 actct
//
LOCUS       DAVKXA010000095         2912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKXA010000095 DAVKXA010000000
VERSION     DAVKXA010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.095"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(101..634)
                     /locus_tag="VW883_002084"
     CDS             complement(101..634)
                     /locus_tag="VW883_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0275138.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(723..1499)
                     /gene="recX"
                     /locus_tag="VW883_002085"
     CDS             complement(723..1499)
                     /gene="recX"
                     /locus_tag="VW883_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0275139.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQNFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1537..2892
                     /gene="rlmD"
                     /locus_tag="VW883_002086"
     CDS             1537..2892
                     /gene="rlmD"
                     /locus_tag="VW883_002086"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0275140.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          923 a          529 c          533 g          927 t
ORIGIN      
        1 aactctgcta taatggattt attccttttt gtgtttacac aatttatttt atactaccaa
       61 aaaaacaagg tcaggatttt gttcctgacc tttgacaact ttaccgattc tttagttcta
      121 catagcgctt gtaccaaatg tttacatagg cttctgagaa aggaccacgt ccattgttaa
      181 tccaatcaac aagaattttg acatgttctt ttaaaatata gtccaagtca tcagaataat
      241 tcattttgcg tttgtgacgc tcgtactctt caacgtccaa gagacgtttt tccccatctg
      301 taaaaatttt aacatccaaa tcgtaatcaa tatacttcag tgcttcttca tccagatagt
      361 aggggctagc catattgcaa tagtaagaag ttccattatc acgaatcatg gcaatgatat
      421 taaaccaata tttcttgtga aagtaaacaa tagccggttc tcgagtgacc caacgacgac
      481 catcactttc ggtaacaagt gtatgatcgt tgacaccaat aatggcgttt tctgttgttt
      541 ttagtaccat ggtgtcccgc caagttcggt ggagactccc atcatgctta taactttgaa
      601 ttgtaataaa gtcgccttct tttggaagct tcataactaa ccaactttct acaatttata
      661 agtttatcat ttactattgt accataaaat tacctaaaat ctgtgaattt cacttggaaa
      721 tattaaagat attctctaag agcgcttgct atatccgaaa aatcgtagcc ctttcgtgct
      781 aaaacttgag ttaaacgctg cttcagttcg tatccttcat actttcgagc atacttagta
      841 tattgcttat caagttcctt gaagatgagt tcttgagtcg tttcttggtc aacttggcta
      901 tctaagtcgt caaaggcaat tttagcatca gaataagaga agcccttgtt agtcaagttc
      961 tggataatct tatcttgcag ggcacgagct ggaagttttc cctcatattt tttcaatagt
     1021 ttattagcta cacgttgagc aacttcagaa aaatcaaatt ctttcaagtt ctcttctata
     1081 gtagattttg aaatcccttt ttgagctagt ttctgagtca gcacataagg acccttgtct
     1141 cctgaaagtt gattggtatt gatgatagca taagcgtact gaccatcatt aatccactta
     1201 tcttctttaa gattagcaat aacttgagaa acgatgtttt tatcaatatc gtattttttc
     1261 agatattctc tgacttcttt ttcagtgcgt gctttaaagg ataagtggta gagggccaga
     1321 ttcttaccat aagaaaattg agcaaagttc tgaatctctt tcaattcctc ttcgcttatc
     1381 accttatctc tcgataacat aaaacgaaca attgtatctt cggtgatata gcatttgtcg
     1441 ccattatcaa gctccatcag atagagtctt tttttctttt caagttttgt gattttcata
     1501 gctctattat aactcaaaat gtgataagat aggggtatga atctgaaagt gaaacaaaaa
     1561 ataccattaa aaatcaagcg catgggaatt aacggtgagg gaatcggctt ttaccaaaaa
     1621 acattagtct ttgtaccagg agctctcaaa ggcgaagata tctattgtca gattacttct
     1681 attagacgca actttgttga agcaaaatta ctgaaggtca acaagaagtc taaatttcga
     1741 attgtgccat cttgtactat ttataatgaa tgcggaggct gccaaatcat gcacctgcat
     1801 tatgataagc agctggagtt caagacggac ttacttcatc aagcgctgaa aaaatttgct
     1861 cctgcaggat atgaaaatta tgaaattcgt ccaactattg gaatgcagga accaaaatat
     1921 tacagagcta agttacaatt tcagactcga aaatttaaaa atcaggtcaa ggcgggctta
     1981 tatgcacaaa actctcacta tttagtagag ttgaaagact gcctggtaca agataaggaa
     2041 acccaagtga ttgctaatcg cttagcagaa ttacttactt atcaccagat tccaatcacg
     2101 gatgagagaa aagttctagg tgtccgtact attatggtcc gacgcgcgag aaagaccgga
     2161 caggttcaga ttattattgt tacaaaccgc cagcttaatt taactcaatt ggtaaaagag
     2221 ttggttaaag atttcccaga agttgtgaca gtagctgtta atacaaatac agctaaaacc
     2281 agtgagatat atggtgaaaa gacagagatt atctgggggc aagagagtat tcaagaaggt
     2341 gtactcaatt atgaattttc actatcccct cgagcttttt atcaactaaa tcctgagcaa
     2401 acagaagtcc tctatagcga agcagtaaaa gcgctggatg ttgataaaga agaccatttg
     2461 attgacgctt attgtggagt tggaacgatt ggatttgcct ttgcaaagaa agtaaaaaca
     2521 ctcagaggta tggatattat tccagaagct attgaagatg ccaagcgaaa tgctaaaaga
     2581 atgggatttg acaatactca ttatgaagct ggaacggcag aagagattat tcctcgttgg
     2641 tacaaggaag gctaccgagc agatgctttg attgttgacc caccacgtac aggtctggat
     2701 gataagttat tagatactat tcttacttat gtaccagaaa aaatggttta tatttcttgt
     2761 aatgtttcga ccttggctcg tgatttggta cgcttagtag aagtctatga tcttcattat
     2821 atccagtcgg tcgatatgtt cccacataca gctcgaactg aagctgttgt aaaattaata
     2881 aaaaaagttt aaaaaaggtg ttgacaaaac at
//
LOCUS       DAVKXA010000096         2910 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKXA010000096 DAVKXA010000000
VERSION     DAVKXA010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.096"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(199..570)
                     /locus_tag="VW883_002087"
     CDS             complement(199..570)
                     /locus_tag="VW883_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275141.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQIMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLIIILFLIWGLKYYKK"
     gene            complement(1038..1157)
                     /locus_tag="VW883_002088"
     CDS             complement(1038..1157)
                     /locus_tag="VW883_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0275142.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(1261..1410)
                     /gene="blpO"
                     /locus_tag="VW883_002089"
     CDS             complement(1261..1410)
                     /gene="blpO"
                     /locus_tag="VW883_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0275143.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(1654..1857)
                     /gene="blpN"
                     /locus_tag="VW883_002090"
     CDS             complement(1654..1857)
                     /gene="blpN"
                     /locus_tag="VW883_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0275144.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(1873..2127)
                     /gene="blpM"
                     /locus_tag="VW883_002091"
     CDS             complement(1873..2127)
                     /gene="blpM"
                     /locus_tag="VW883_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0275145.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            complement(2277..2910)
                     /locus_tag="VW883_002092"
                     /pseudo
     CDS             complement(2277..2910)
                     /locus_tag="VW883_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          981 a          601 c          403 g          925 t
ORIGIN      
        1 attcatagaa ctatagtaaa atgaaataag aacaggataa atcgatcagg acagtcaaat
       61 cgatttctaa caatgtttta gaagtagagg cgtactattc tagtttcaat atactatacc
      121 atattttgtt tcgcagggaa tctattataa aagggtaagt atttcaaaaa cacttacccc
      181 tttatacttt attaagctct actttttata atacttcaag ccccaaatga gaaaaagtat
      241 aataatcaag cagagaatag caccaatgta ggcaattatt tgttggtagg attctcctgc
      301 tgtgatccct ctatacaaac aaataataga cataaaacct gtcaagccga tgaacatgat
      361 ttgattagtt ctaggactaa ccaaatcatc gtcttcaaac tcttttatcc gcatttccct
      421 agtgaggtaa acagtgacca aaatagaagc taagttaata accactaaaa gaaattggaa
      481 aactgacgaa atagaaatag ataagtagaa acaagcaaag gcaactgacc caggaacaat
      541 ctcacaaaga atatgattct ttttaatcaa gaaaatcttt catttctttt ctttctttct
      601 aattaaagaa aaatagatca taaccgcaat catataggct atggtataaa atagattata
      661 ccaaatactc tccctaagcg gataaagaaa gatggacatg atcagataca gaacgaaaat
      721 aatcagtatt tttttcttca taagatttcc tcctaaatgt gcgatttatc ttagttgagc
      781 aagaacattt acactgctag tatagcactt attttgacct tggatcactc aaatcataaa
      841 tggtcatcaa aacctcttga attgtaaaaa ttaaaaaagc aagcatgaaa aacatacttt
      901 cctctttata ttgtattgat accaacttgt ttgtagactt ttcatcctgc tatcacatat
      961 cattttgaca ggcgaaacaa tattaaagaa actcccctgt aaattaagct agcaaataca
     1021 ggggagaaat ttatttttta gagagtacta tccgtatcct ttttggaaga ttttgaaaat
     1081 atttttctaa ttaagtcatc catataagga ccaaatatac caactactaa accaataata
     1141 aaacttttaa aatccataat taccatcaac atattgctgc ataggctaca cctccaagta
     1201 tagctccacc tgcagcacca gttacaccta ttcctatagc aaatggtccc aatagaaatg
     1261 tcaaaccgtt gttgcacacc catcaattgc gccatatgca acccctgctg cacaactaat
     1321 ttttcttccc caatcaatat ctccaccttc aacgcaagca agcatttcat tatccataac
     1381 tgcaaattgt gacatcattt ttgtatccat atagtatatc acttttcagt tacggaacaa
     1441 gtttaatata aaaattatca aaaaaacata ggcaataaag agaaaaatta atttatcata
     1501 gattagaaat aatatgacaa aacaattcaa tgatgttaat tcaatagtct tttgtttttt
     1561 atcggagata cttatggata gataaataag ataggtttga aaagcgaaga gaataataaa
     1621 gaatatagcc ttcataaaat ttagctttca tttttatgat gtagcggtat aggctaaata
     1681 tccacaaacc actgctcctc caattcctcc tattgcagcg ccccatggtc ctagaagtct
     1741 cccatatttc actccacccg ctgcacaacc taaagcagca actacagctg ctcctccgga
     1801 attacctcca taaacctcac tcagcattgt ttcatttata ttacaataag tattcataca
     1861 agtctccttt tattaaaatc cacccgttgc ccctgttact cctgcccaaa gatccacacc
     1921 aaatttagct cctatgtatc cacatgctcc cataaatggt gctccaacac cactcgcagc
     1981 acaaatagct gtccctagcc cccagccacc aaaagcagca ccaccacctt ctaagacatt
     2041 agtttgccaa ttattcttgc ctccttcaat actagataac atagttatat ccatttcatg
     2101 aaattgttcc ataatttttg tatccatgac aaatactctt ttttattttt aatttttgtc
     2161 ttgttgtaac tttgacaagt ttagtatatc atcgtttttt aaaatttttc atccagatct
     2221 tgaatagtca tcgaaacgtc ttgaattgca aaaattacat tagacttcct gcaaaactag
     2281 aatcctagtt catgattgat aataccaaca ctcaaattca ttcgtaatcc gaagcgttta
     2341 cgatgatttc gataggttgt tgcaaacatt ttaaacgttt ttactttggc aaagatgttc
     2401 tcaaccttgc ttctctcctt agatagcgca tggttacagg ctttatcttc aactgttagc
     2461 ggtttgagtt tgctggattt acgtgaagtt tgtgcttgag gatatatctt catgagccct
     2521 tgataaccac tgtcagccaa gatttttcca gcttgtccga tatttctgcg actcattttg
     2581 aacaacttca tatcatgaca atagttcaca gtgatatcca aagaaacaat tctcccttga
     2641 cttgtgacaa tcgcttgagt cttcatagcg tgaaatttct ttttaccaga ataattcgct
     2701 aattcttttt ttagggcgat tgatttttac ctctgttgca tccacaatca ccgtatcctc
     2761 agcactaaga tgagtttttg aaatcgtaac accactttga acaagagtta cttcaaccca
     2821 ttggctccga cggattaagt tgctttcgtg aataccaaga tcagccgcaa tttcttcata
     2881 agtgcggttc tcacacatat tgaagagtgg
//
LOCUS       DAVKXA010000097         2782 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKXA010000097 DAVKXA010000000
VERSION     DAVKXA010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.097"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..799
                     /locus_tag="VW883_002093"
     CDS             <1..799
                     /locus_tag="VW883_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0275146.1"
                     /translation="RNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISF
                     LDDDDEYMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQ
                     MVHNIAGTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYA
                     HSKENGITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDK
                     CKALKVIKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            809..2425
                     /locus_tag="VW883_002094"
     CDS             809..2425
                     /locus_tag="VW883_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0275147.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT         1008 a          319 c          506 g          949 t
ORIGIN      
        1 aagaaataaa attatccatc aatttggcta taccaatcat agaattaagt taattttaag
       61 taatgaagat ttaggtgcaa ctaatgccag aaacataggt ataaaaaatt ctagaggtaa
      121 gtatatatca tttttagacg atgatgatga atatatgcca gatcgaattt taaagttgat
      181 ggcttgtttt aaaaagagta gaatgaagaa tttagcttta gtttatagtt atggaataat
      241 aatttatcca aatggtacac gagaagagga gaagaccgat tttgttggaa atcccttgtt
      301 tgttcaaatg gttcacaata tagcaggtac gtcattttgg ttgtgtaaaa aagaggtgct
      361 agaattaatt aatggttttg agaaaataga ttcacatcag gacggtgttg ttttattaaa
      421 actacttgct caaggatacc aaattgatat agtgcgagaa ttcttggtga attactacgc
      481 tcacagtaaa gaaaacggta tcactggagt gacacaaaaa acaattaatg cagatgaaga
      541 atattataat tactgtagga aatattttaa tttattgagt ttcaacgaga gaatattggt
      601 tacaaagaaa tattattctt taaacataaa gcggttacta ttaataggag acaaatgcaa
      661 ggctttaaaa gtaatcaaga aggcaagaga agaaaaaatt tttaacgaat ttcttttttt
      721 gaaatacatg ttattatatt attttggttt tttctattgt atatatgaca actatgttca
      781 attaaaattt agaaagtgag aaactattgt gtatactatt ataaaatcaa atataaaaaa
      841 atttagttta ttaacgatat ttattgttgc tggtcaatta ttgctaattt atgcagcaac
      901 tattaatgct ctggtgttga atgaattaat tgcgatgaat ttagagcggt ttttgaaatt
      961 gtcaatctac caaatgattg tctggtgtgg gataatattc cttgactggg tagtgaaaaa
     1021 ttatcaggtt gaagtgatcc aagagtttaa tctagagatt cgaaatagag ttgccacaga
     1081 catctctaac tctacctatc aagaatttca tagtaaatca tcaggaacat atctttcgtg
     1141 gctaaataat gatgttcaga ctttaaatga tcaggctttt aaacaacttt ttttagtaat
     1201 aaaaggaatt tctggtacta tatttgcagt tgtgactctt aatcactatc attggtcatt
     1261 gactgtagcc accttgtttt cattaatgat tatgctactt gtaccaaaaa tctttgcatc
     1321 gaaaatgcga gaagttagtc taaatttaac tagccaaaat gaagcttttt taaaatctag
     1381 tgagactata ttgaatggat ttgatgtgtt agcgtccttg aatcttttat atgtattgcc
     1441 taagaaaatt aaagaagcag gaattttatt aaagatggtt atacaaagaa agacaactgt
     1501 agaaacgtta gcaggcgcta ttagcttctt tctcaatatt ttttttcaga tatctctcgt
     1561 ttttttaaca ggctatcttg caataaaagg aatagtgaaa attggtacta ttgaagcaat
     1621 aggagcacta acaggtgtta tttttacagc gctaggtgaa ttaggaggtc aattatcctc
     1681 tattattggt acgaagccta tttttttaaa attgtattca attaatccaa ttgagtcaaa
     1741 taaaatgaat gatatcgaac caaatgaggt gaatagagat tttccgttat atgaagcaaa
     1801 aaatatttgc tataagtatg gagataaaga aatattaaaa aacttaaatt tttgttttca
     1861 acgtaatgaa aagtatttaa ttttaggtga aagtggaagc gggaaatcta cattattaaa
     1921 attattgaat ggctttttga gagattatag tggagaattg cgattctgcg gggatgatat
     1981 aaaaaaaacc tcctatttaa atatggtttc gaatgttcta tatgtagatc aaaaagctta
     2041 tttgtttgaa ggtacgatta gagataatat tttattggaa gaaaattata ctgatgaaga
     2101 aatactacag tctttagaac aagttggttt gagtgtaaaa gattttccta ataacatttt
     2161 agattattat gttggtgatg atgggagatt actgtcagga gggcagaaac aaaaaattac
     2221 tttagctaga ggcctaatta gaaataagaa aatagtatta attgacgagg gaacttctgc
     2281 tatcgatagg agaacttcgt tagcgattga acgtaagata ttagatagag aggatttgac
     2341 tgtcattatt gttacccatg ctccgcatcc ggaacttaaa caatatttta ctaagatata
     2401 tcaatttcca aaggatttta tttaagaata taggggaggg aaacatgaga ttctattgtg
     2461 aagcttatga ggtaattact gaagagaaaa aagtatcatt tttttatgta gatgagaaac
     2521 ccttaaggta tctgttattt gactatatat ttctactagt tctagctaaa aaaaaatatc
     2581 ccaatcttat gaactgcacc ccaaaagtta gatttattct gtctaacttt tggggtgcag
     2641 ttcattttgc atagttttgg cattcatcct agatatccat ataaaatgtc tgagattgtt
     2701 gaaatgtcta aaaaaatatc aaatctaaac gataaaaaag aatttcacaa aaagaactgt
     2761 gagttgaggt ttcaagatag tg
//
LOCUS       DAVKXA010000098         2258 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKXA010000098 DAVKXA010000000
VERSION     DAVKXA010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.098"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..426
                     /locus_tag="VW883_002095"
     CDS             <1..426
                     /locus_tag="VW883_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275148.1"
                     /translation="NSESYTHRVLGIVNFFKYYESSKFHLFFGDAELAFGDMTKGYTH
                     NIRSVLGWDGTVEMPLLSVMIKNGYVGLIGYGVVLFKFISSVLSMEDRRVKNIGLSIL
                     IPLLLSAMVENYIVNISFVFMPVCFCILCSIKNIEFKNN"
     gene            436..1404
                     /locus_tag="VW883_002096"
     CDS             436..1404
                     /locus_tag="VW883_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0275149.1"
                     /translation="MKKVSIILPVYNVEQYIKKCLESIQQQTYPNLEVIIVNDGATDK
                     SVEYCEQICKIDSRFSVTHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSYL
                     VSSMENNEADIAICDPAHYYSDRQNNDLNIFYPASSVKVYEKTEALCEMFYQKSFLVS
                     AWAKIYKKELFDDIRFPVGKLFEDSAVMYLLFEKCEKIVYSNAKLYAYVHRDNSITTK
                     KFSDKDLDILDISNTILDHYSGNFRVYKAAVSYKVSACFRILLNSSSEKKYNQIQKDC
                     MTYILRNWRNVLFDKNVRLKNKLALISITLFNPFVKFIYSKVNRWE"
     gene            1411..>2258
                     /locus_tag="VW883_002097"
     CDS             1411..>2258
                     /locus_tag="VW883_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HEV0275150.1"
                     /translation="MNKYEERYQEDLSKNDFEKLINRRYLSDKELQVEYVKKGTVLPP
                     KVFEMKLSNKLGLQKALHGKGGVVDSKGNYVELSEQKAVGMRNRVYGSYKFNHKNLAI
                     RNEKVIYLNYFINQWGHFLLDVVGRLWYPLLKDTDTKLDYTCYAGTETKLEGNYLEFL
                     ELLGIDKSRLILINRPTQFSEIIIPESSILPGEYYTKEYKMLFNSLVANVKLDNNLES
                     KKIYCSRARLDLAKGKEFGENGIEKVFLKNGYTPVYMETMSLKEQIRTLLSATTIVLT
                     SGSLAH"
BASE COUNT          815 a          283 c          408 g          752 t
ORIGIN      
        1 aatagtgaat cctatactca tcgtgttttg ggtattgtta atttttttaa atactacgaa
       61 tctagcaaat ttcatttatt ttttggtgat gctgagttag cctttggtga tatgacgaaa
      121 ggttatactc acaatataag aagtgtttta ggttgggatg gaactgtgga aatgccgttg
      181 ctaagtgtta tgataaaaaa tggttatgtc ggcttaatag ggtatggagt agtcttattt
      241 aaatttatat cctctgtatt atctatggaa gatagaagag taaaaaatat tggcttatcc
      301 attctaatac ctctacttct atcagcaatg gttgaaaatt atatcgttaa tattagcttt
      361 gtattcatgc cggtctgttt ttgtatttta tgctcaataa aaaatataga atttaaaaat
      421 aattgaaagt gatttatgaa aaaagtaagt attattctac ctgtctacaa tgttgaacag
      481 tatataaaaa aatgcttaga atcaattcaa caacaaactt atccaaattt ggaagtaatc
      541 attgttaatg acggagcaac cgataaaagc gttgaatact gtgagcaaat ttgtaagata
      601 gattctaggt tttctgtcac tcacaaagaa aatggtggac tttccgatgc aagaaatgtc
      661 ggtatagata aagccaaggg agattacctc atttttgttg acagtgatga ttttgtctct
      721 caagatatgg tatcttattt agtatctagt atggagaaca atgaggcaga cattgctatt
      781 tgcgatcctg ctcattatta tagtgaccgt caaaacaatg atcttaatat tttttatccg
      841 gcatcaagcg ttaaggttta cgaaaaaacg gaagctctat gtgagatgtt ttatcaaaaa
      901 tcttttttgg tatctgcttg ggctaagata tataaaaagg aactatttga tgatatcaga
      961 ttccctgttg ggaagttatt tgaagatagt gctgttatgt atctgctttt tgaaaaatgt
     1021 gaaaagatag tatattctaa tgcgaaatta tatgcctatg tgcatagaga caatagtatt
     1081 acaacaaaga agttttcaga taaagattta gatattttag acatttcaaa tactattctt
     1141 gatcactata gtgggaactt tagagtttat aaagcggcag tttcctataa agtttcggca
     1201 tgttttagaa ttttgttgaa ctcatcttca gaaaaaaaat ataatcaaat acaaaaagat
     1261 tgtatgacat atattttacg aaattggaga aatgtgttat ttgataaaaa tgtccgatta
     1321 aagaacaagc ttgccttgat ttctataact cttttcaatc cttttgttaa atttatctat
     1381 agcaaagtaa acagatggga ataatagcaa atgaacaaat atgaagaaag atatcaggaa
     1441 gatttatcta agaatgattt tgagaaacta atcaatagaa gatacctatc ggataaagaa
     1501 ctacaagttg aatatgtaaa aaaaggaaca gtgttacctc ccaaggtctt tgaaatgaaa
     1561 ctatcaaata aacttggtct acaaaaagct ttgcatggga aaggtggtgt tgtagattca
     1621 aaggggaatt atgttgaact ttctgaacaa aaagcagttg ggatgagaaa tcgagtctat
     1681 ggatcttaca aatttaacca taaaaatttg gctatcagaa atgaaaaagt tatttaccta
     1741 aactatttca taaatcagtg gggacatttt ttactagatg ttgtggggag attatggtat
     1801 ccattactaa aagatactga tactaaactg gattacacat gttatgctgg tacagaaacg
     1861 aaacttgaag gaaactattt agagttttta gaactcctcg gtatagataa atcacgctta
     1921 attttgataa atcgcccaac tcaattctca gagataatta tacctgaaag ttcaattctg
     1981 ccaggtgaat attatacaaa agaatataaa atgcttttta attctttagt agcaaatgtt
     2041 aaattagata acaatttaga atcaaaaaaa atttattgtt cacgagctag gctagattta
     2101 gcaaaaggta aagagttcgg tgagaatggt attgaaaagg tcttcttaaa aaacggttat
     2161 actccagttt atatggaaac aatgtctttg aaagaacaaa taagaacgct attatcagct
     2221 acaacaatag tattaactag cggttcgttg gctcataa
//
LOCUS       DAVKXA010000099         2168 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKXA010000099 DAVKXA010000000
VERSION     DAVKXA010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.099"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            43..915
                     /locus_tag="VW883_002098"
     CDS             43..915
                     /locus_tag="VW883_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0275151.1"
                     /translation="MIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQT
                     MLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKD
                     GFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLI
                     VSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPI
                     ACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSP
                     YLIYLLIKMNRRNI"
     gene            915..1709
                     /locus_tag="VW883_002099"
     CDS             915..1709
                     /locus_tag="VW883_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0275152.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVMANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT          800 a          330 c          358 g          680 t
ORIGIN      
        1 ttcattttac ttatcggaga tgaaagttat tctttttcaa ctttgattaa agtcttaaat
       61 agtgaaactg ttcctggagc tagtttttcg attatggaaa ttagattacc aaaattatta
      121 gcaggaatta tagctggctg gtcttttgga ttggcaggat ttatctttca aactatgtta
      181 agaaatcctc ttgcaagtcc tgatataatc ggtgtcacaa gttcttcatc tattgcagcg
      241 gtcttttgca tattggtatt aaaaacaaat agtttaacta ctggaattat ttcaataact
      301 tgtggactaa catcatcttt aatattattt ttactagcta aaaaagatgg tttttcagca
      361 gcaagactga taatattagg tattggtttt caagctgtca caagagcagg cacctcattt
      421 ttattgttga aagtagcaag atatgaatta caagaagtta tgagatggct cagtggctct
      481 ttatctttta caaagttaga tgacatacct cttgttctaa tagtaagtat tattgctact
      541 atattagttt tattttttaa taaaagacta gaaattattg aacttggtga agaaatagca
      601 atcggacttg gtgcaaatcc cgagctttca aggcttgttt taattttttg cgctgtatct
      661 ttaactgctt tttctacttc aattacagga ccaatagctt gtatatcttt tttagctggt
      721 cccatagcct taaatattgg caagaaaaga agcccaatat tagctggatt ggttggaatt
      781 ttactagttt tgttatcaga catattctct caaaatattt taccagctag atatccagta
      841 ggtgttgtaa ctggcttgtt aggttcacca tacttaatat atttactaat aaaaatgaac
      901 aggaggaata tataatgaaa ggtctgtggt caaataatct tacctgcggt tatgatgaaa
      961 aaataatctt ggaaaatata aatataaaaa tacctgaaga aaaaatatca gttattattg
     1021 ggtcaaatgg ttgtgggaaa tcaacactca ttaaaacctt gtctcgactt ataaagccat
     1081 tagagggaga agtattgctt gataataaat caattaattc ttataaagaa aaagatttag
     1141 caaaacacat agctatatta cctcaatctc caataatccc tgaatcaata acagtagctg
     1201 atcttgtaag ccgtggtcgt ttcccctaca gaaagccttt taagagtctt ggaaaagatg
     1261 accttgaaat aataaacaga tcaatggtta tggccaatgt tgaagatcta gcaaataacc
     1321 tagttgaaga actttctggg ggtcaaaggc aaagagtatg gatagctcta gccctagccc
     1381 aagatacaag tatcctactt ttagatgagc caactactta cttggatatc tcatatcaaa
     1441 tagaactatt agacctcttg actgatctaa accaaaaata taagacaacc atttgcatga
     1501 ttttgcacga tataaatcta acagcaagat acgctgatta cctatttgca attaaagaag
     1561 gtaaacttgt tgcagaggga aagcctgaag atatactaaa tgataaacta gttaaagata
     1621 tctttaatct tgaagcaaaa attatacgtg accctatttc caattcgcct ctaatgattc
     1681 ctattggcaa gcaccatgtt aactcttaat aattgaatat tggaattcat ttaaaagtcg
     1741 caacttttga actgaccctc aaaagttagg acaaaaaact aactaaagga ggtcagtttt
     1801 ttaatggcaa atacagcaca gaatttaaga taaaattagt aaaagaatat catgaatgaa
     1861 aaataggata tagagaataa cagcaatatt aaaaagatca ggactgataa taaacaaaaa
     1921 gaaagtacaa cgactagttc aaaagctaaa acttcaagta aaaagttatt caagaaaatc
     1981 tagaaaatac tcatcctaca aaggacaggt aggaaaaata tcagacaaca aaataaaaag
     2041 aaatatttat taccgaaaaa aaggggaaat cgagtcaagt accaacaggc tcatctattc
     2101 caaaaagata tttactcgat ggaaaaactc ctagaattag tgctacaaat attgacaatg
     2161 gtatctta
//
LOCUS       DAVKXA010000100         2146 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKXA010000100 DAVKXA010000000
VERSION     DAVKXA010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.100"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(10..960)
                     /locus_tag="VW883_002100"
                     /pseudo
     CDS             complement(10..960)
                     /locus_tag="VW883_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1037..1492
                     /locus_tag="VW883_002101"
     CDS             1037..1492
                     /locus_tag="VW883_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0275153.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYSNPAYFY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            1657..1956
                     /locus_tag="VW883_002102"
     CDS             1657..1956
                     /locus_tag="VW883_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0275154.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          698 a          408 c          372 g          668 t
ORIGIN      
        1 ctgctatagt caattgaaac aagaacagga caaaagagcc tcgtaaaagg tattgcaact
       61 tggtaatacc tttttgaggt gctttttgat atgagcccat gttttctcaa taggattgta
      121 ctcaggcgag tagggaggaa gaggtaaaag tttatgccca aactcttcgc ataaaagttc
      181 tagcttcccc attctatgga atcttgcatt atccataata tagtagattg aaactagaat
      241 agtacacatc tacttctaaa acattgttag aattcgattt tactatcctg atcgatttat
      301 cctattctta ttttatttta ctataataac cgatggtgtg gttaatgttg gtaagagaaa
      361 cttctgaaac caagcttcaa aaaagtcgct cgtcatcgtc tcttcgtaag tcattggagc
      421 gattaattca ccatttgtta gacctgcaac caaagaaatc ctctgatatc ttcttccaga
      481 tactttgcct cttattaact gaccttttaa tgagcgacca tattctcgat aaaaataagt
      541 atcgaatcct gtttcgtcaa tctaaacagg tgctaggtgc tttaaactat taaaattctt
      601 aagaaataag gctacttttt ctgggtcttg ttcatagtag gtgtggttct tttttcgagt
      661 gtagcccata gctttgagcg catagtggat ggtagttgga tgacagccaa attcagaagc
      721 tatttcagtc aaataagcgt ctggattgtc agtaagatag tttttaagtc tatctctatc
      781 aacttttctt ggttttgttc cttttacttg gtggtttagc tctcctgttt tctcttttag
      841 ctttaaccag ccataaatgg tattacgtga gatttggaaa acgtgtgatg cttctgttat
      901 actacctatt cgctcacaat aagagagaac ttttttacga aaatctattg aatatgccat
      961 aagaagatta taccacattg tgtactattt ttggttcatt tcactataat aataacgata
     1021 ctagataatg aggaaaatgc aatggcaaac ccaactttcg gagaaaaaag cgaatacaga
     1081 ctatattgct cgctatggcg tatatgcagt tatccctaat cctgaacaaa aacaaattgt
     1141 tcttgttcaa gaaccaaatg gtgcttggtt cctaccatgt ggagaaattg aagcaggtga
     1201 aaatcatcag gaagccctaa agcgtgagtt gattgaagag cttggtttca cagcagaaat
     1261 tggtacctat tacggacaag ctgacgaata tttctattct cgtcatcgtg atacctacta
     1321 ctccaatcct gcctacttct atgaagcaac tcctttcaaa gaagtacaaa agccactaga
     1381 aaactttaat catattgcct ggttccctat tgacgaggct atcaaaaacc ttaaacgtgg
     1441 tagccataaa tgggccattg aatcttggaa aaaacagcat aagattgact aatactcttc
     1501 gaaaataaaa ttcaaaccac atcagcgtcg ccttaccata ctcaagtata gcctgcggct
     1561 agcttcctag tttgctcttt tattttcatt gagtataaat caagcgactt tattcaaaaa
     1621 gtgctataat agaattagaa aaccggagga aatattatga agcttatcaa tacgacaaac
     1681 tcacactcgc aacttgtaaa aagtcagcta gaaagtaccg atgcaaccct tgttgaggtt
     1741 tattctgcag ggaatacaga tgttattttt acccaagctc cgcttcacta tgaaatcctc
     1801 atctcaaaca aacaccgtgc tattcgtgag cctgaaatcg aaaccattca agaatttttc
     1861 ttgaaacgta aaattgataa gacctctgtt gatgaagcca atatcaagac actctactca
     1921 gagaaattaa ttggaatttc aatcccaatc aagtaagaaa attgagtaaa aactcgattt
     1981 gagagaaagt ccaataagtc tttccataac aaaacgcata gtaacaagag tttctacacc
     2041 cactattatg cgtttttatc attttgaaat ctactgcaat caatgaagaa gcaaagatca
     2101 aactaggcag ctagttacaa gttacgtaag cgcgtcataa caaggt
//
LOCUS       DAVKXA010000101         2074 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKXA010000101 DAVKXA010000000
VERSION     DAVKXA010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.101"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            20..1045
                     /locus_tag="VW883_002103"
     CDS             20..1045
                     /locus_tag="VW883_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0275155.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1035..2042
                     /locus_tag="VW883_002104"
     CDS             1035..2042
                     /locus_tag="VW883_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0275156.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
BASE COUNT          731 a          291 c          371 g          681 t
ORIGIN      
        1 atatgtttaa ggagttttta tgaaaaacaa attttttcta atagctattt tagctatgtg
       61 tatagttttt agcgcttgtt cttctaattc tgttaaaaat gaagaaaata cttctaaaga
      121 gcatgcgcct gataaaatag ttttagatca tgctttcggt caaactatat tagataaaaa
      181 acctgaaaga gttgcaacta ttgcttgggg aaatcatgat gtagcattag ctttaggaat
      241 agttcctgtt ggactttcaa aagcaaatta cggtgtaagt gctgataaag gagttttacc
      301 atggacagaa gaaaaaatca aagaactaaa tggtaaagct aacctatttg acgatttgga
      361 tggacttaac tttgaagcaa tatcaaattc taaaccagat gttatcttag caggttattc
      421 tggtataact aaagaagatt atgacactct atcaaaaatt gctcctgtag cagcatacaa
      481 atctaaacct tggcaaactt tatggagaga tatgattaga attgattcaa aagccttagg
      541 tatggaaaaa gaaggtgatg agttaatcaa aaatactgaa gctcgtatat ccaaagaatt
      601 agaaaaacat ccagaaatca aaggaaaaat caaaggaaaa aaagtattat ttactatgat
      661 taatgctgca gatacatcaa aattctggat ttatactagc aaagatccaa gagcaaatta
      721 tttaacagat ttaggtctag ttttccctga atcattaaaa gaatttgaga gtgaagatag
      781 ttttgcaaag gaaatttctg cagaagaagc aaataagata aatgatgctg atgtaatcat
      841 aacttatggt gatgataaaa ctcttgaagc tttacaaaaa gatcctcttt taggtaaaat
      901 aaatgcaatt aaaaatggtg ccgttgctgt aattccagat aatacaccgt tagcagcctc
      961 atgcactcca acaccacttt caataaacta tactattgaa gaatatctaa atcttttagg
     1021 aaatgcatgc aaaaatgcga aataaaaaac aaataaacct aggcataatt tttgtaatct
     1081 gcctaggtct tcttattaca atatttttgt cattaaagct tggaacaaaa gaaattaata
     1141 tcagagattt tttagcagct tttggaatgg gtaatacaaa tgatgatttt attaaatcaa
     1201 ttatatataa aagaatacct agaactattt ttgcaatttt agcaggttct agtcttgcca
     1261 taagcggtgt attgatgcaa tcagttacta gaaacccaat agctgatcca ggtatactcg
     1321 gtataaacac aggagcaagt cttagtgtag taattggtct ttctttttta ggaatttcat
     1381 caagcataag ccatataagt tttgcaatca ttggtggctt agtaagtgca atttttgtat
     1441 acgcgattgc tgtaagcgga aaagcaggcc ttacccctat aaaacttgcc ttatcaggaa
     1501 cttgtgttag tatggcttta agcagttttg taagtttttt aattttaccg aataataacg
     1561 tcttagacaa atttagattt tggcaaatag gtagccttgg agcagctaca ttatcttcta
     1621 tatctacact actacctttt ataattttag gtcacttgat agctatattt atttcatcag
     1681 atttaaacgc tttagctatg ggtgatgaaa tggctgttgg tcttggagtt aatgttaata
     1741 ggataagatc acttgcaata attgcaagtg tgcttttatg ttcaagtatt actgcaattg
     1801 gtggacctat tggcttcgta ggtcttatag ttcctcactt ttgtggctta tttataagca
     1861 aagatatacg cacaatgacc atttcttcat cttttatagg tgcagagctc ttgcttatat
     1921 gtgatataat cggccgtatg ttaggtaaac caggtgaaat tgaagtaggg ataattactg
     1981 caataatcgg gggtccagta cttatttatg taactatgaa aaatagaggg gttaataact
     2041 aatgcaaaat ttaattatag gtattcaaaa aaga
//
LOCUS       DAVKXA010000102         1870 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKXA010000102 DAVKXA010000000
VERSION     DAVKXA010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.102"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            309..1655
                     /gene="gdhA"
                     /locus_tag="VW883_002105"
     CDS             309..1655
                     /gene="gdhA"
                     /locus_tag="VW883_002105"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0275157.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
BASE COUNT          590 a          358 c          355 g          567 t
ORIGIN      
        1 tggtataaat attgctttcc tccaaaatgg tcataatttt actagcaaat ctaacatatc
       61 acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt atagcatacc
      121 atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg tttttttatc
      181 tattttcaaa aaaaaccaaa aactgaattg aaagaatttt tagaaaattt ctgttttttc
      241 tttacagtga aaaaaaattc tgctataatg tcttatgtaa taaaatatga caataaaagg
      301 agaacgatat gacatctgct aaagaatata tccaaagcgt gtttgaaact gtaaaagctc
      361 gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac actttggaac
      421 ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt attactgagc
      481 ctgagcgcgt gatttctttc cgtgttcctt gggttgaccg tgatggaaaa gttcaagtaa
      541 accgcggcta ccgtgttcaa ttcaactcag ctgttggacc atacaaaggt ggacttcgtt
      601 tccacccaac tgtaaaccaa gggatcttga aattcctcgg atttgaacaa atctttaaaa
      661 atgtcttgac tggacttcct atcggtggag gtaaaggtgg atcagacttc gatcctaaag
      721 gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa ttgcaaaaac
      781 acatcggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga cgtgaaattg
      841 gttaccttta cggtcaatac aaacgtctta accaatttga tgctggtgtc ttgactggta
      901 aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac ggtttggttt
      961 actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag aaagtcgtta
     1021 tttcaggttc tggtaacgtt gctcaatacg ctcttcaaaa agcaaccgaa cttggtgcaa
     1081 cagttatctc tgtttctgac tcaaacggct atgttatcga tgaaaacggt atcgacttcg
     1141 atcttttggt tgatgttaaa gaaaaacgtc gcgctcgttt gactgagtat gcagctgaga
     1201 aagcaactgc tacttatcat gaaggttctg tatggactta cgctggaaac tatgacattg
     1261 cgcttccatg tgctactcaa aacgaaatca acggtgaagc agctaaacgt ttggttgctc
     1321 aaggcgttat ctgtgtatct gaaggtgcca acatgccaag caaccttgat gccatcaaag
     1381 tttacaaaga aaatggtatc ttctacggac ctgccaaagc tgccaacgct ggtggtgtag
     1441 ccgtttcagc ccttgaaatg agccaaaaca gccttcgcct ctcatggact cgtgaagaag
     1501 ttgatggacg tctcaaagac atcatgacca acatctttaa cacagctaaa acaacttcag
     1561 aaacatatgg tcttgataaa gactaccttg caggagctaa cattgctgcc tttgaaaatg
     1621 tagcaaacgc tatgattgca caaggcgtgg tataaaaaaa aattacggaa actgactacc
     1681 cagacgggta gccagttttt tcaattccta aaatttaaga ttctaatacc ctttatgcaa
     1741 aaatatagaa ttctaccttt ttctttatat aggctaatgt ttttaatata tttattgtct
     1801 atttttgaaa agacaataaa actatcctac tatagattat catttcccac aattcataac
     1861 tcaaacctaa
//
LOCUS       DAVKXA010000103         1844 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKXA010000103 DAVKXA010000000
VERSION     DAVKXA010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.103"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..281
                     /locus_tag="VW883_002106"
     CDS             <1..281
                     /locus_tag="VW883_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0275158.1"
                     /translation="EPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSN
                     AKLEATNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(415..502)
                     /locus_tag="VW883_002107"
     tRNA            complement(415..502)
                     /locus_tag="VW883_002107"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Ser,seq:gct)
     gene            complement(509..582)
                     /locus_tag="VW883_002108"
     tRNA            complement(509..582)
                     /locus_tag="VW883_002108"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(546..548),aa:Ile,seq:gat)
     gene            complement(618..688)
                     /locus_tag="VW883_002109"
     tRNA            complement(618..688)
                     /locus_tag="VW883_002109"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(654..656),aa:Gly,seq:tcc)
     gene            complement(708..780)
                     /locus_tag="VW883_002110"
     tRNA            complement(708..780)
                     /locus_tag="VW883_002110"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(745..747),aa:Phe,seq:gaa)
     gene            complement(784..857)
                     /locus_tag="VW883_002111"
     tRNA            complement(784..857)
                     /locus_tag="VW883_002111"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(821..823),aa:Met,seq:cat)
     gene            complement(871..960)
                     /locus_tag="VW883_002112"
     tRNA            complement(871..960)
                     /locus_tag="VW883_002112"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(922..924),aa:Ser,seq:tga)
     gene            complement(971..1044)
                     /locus_tag="VW883_002113"
     tRNA            complement(971..1044)
                     /locus_tag="VW883_002113"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1008..1010),aa:Ile,seq:cat)
     gene            complement(1058..1131)
                     /locus_tag="VW883_002114"
     tRNA            complement(1058..1131)
                     /locus_tag="VW883_002114"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1095..1097),aa:Met,seq:cat)
     gene            complement(1137..1210)
                     /locus_tag="VW883_002115"
     tRNA            complement(1137..1210)
                     /locus_tag="VW883_002115"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1174..1176),aa:Pro,seq:tgg)
     gene            complement(1226..1299)
                     /locus_tag="VW883_002116"
     tRNA            complement(1226..1299)
                     /locus_tag="VW883_002116"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1263..1265),aa:Arg,seq:acg)
     gene            complement(1309..1394)
                     /locus_tag="VW883_002117"
     tRNA            complement(1309..1394)
                     /locus_tag="VW883_002117"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1358..1360),aa:Leu,seq:taa)
     gene            complement(1402..1473)
                     /locus_tag="VW883_002118"
     tRNA            complement(1402..1473)
                     /locus_tag="VW883_002118"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1439..1441),aa:Gly,seq:gcc)
     gene            complement(1496..1568)
                     /locus_tag="VW883_002119"
     tRNA            complement(1496..1568)
                     /locus_tag="VW883_002119"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1533..1535),aa:Thr,seq:tgt)
     gene            complement(1587..1668)
                     /locus_tag="VW883_002120"
     tRNA            complement(1587..1668)
                     /locus_tag="VW883_002120"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1632..1634),aa:Leu,seq:tag)
     gene            complement(1674..1746)
                     /locus_tag="VW883_002121"
     tRNA            complement(1674..1746)
                     /locus_tag="VW883_002121"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1711..1713),aa:Lys,seq:ttt)
     gene            complement(1771..1843)
                     /locus_tag="VW883_002122"
     tRNA            complement(1771..1843)
                     /locus_tag="VW883_002122"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1808..1810),aa:Asp,seq:gtc)
BASE COUNT          537 a          490 c          379 g          438 t
ORIGIN      
        1 aggaaccaga gaaatttttc ggacttattg aggacaatct taagcaggtt catcctattt
       61 ttcagactgt ctttaaaacc ttcctcaaag ataaagaaaa gattgtcaac gcccttcaac
      121 tacactattc taacgccaaa ctggaagcga ccaataatct catcaaactt atcaagtgca
      181 atgcctttgg ttttcgaaac tttgaaaact ttaaaaaacg gatttttatc gctttgaaca
      241 tcaaaaaaga aaggacgaaa tttgtccttt ctcgagctta gcttttcttc aacccactac
      301 agttgacaaa gagccataaa aataacttca gattagtaat tcaattaagt tttacggatc
      361 tgaagcttta ttgtctctaa aaataaaaaa gagagttaca aactctcatt aaaacggaga
      421 ataagggatt cgaacccttg cgccagttac ccgacctaac gatttagcaa accgtcctct
      481 tcagcctctt gagtaattct ccaattaatg ggcacgagtg gactcgaacc accgacctca
      541 cgcttatcag gcgtgcgctc taaccacctg agctacgcgc ccaagttaaa aaacttggta
      601 atttgaacaa agttcaaagc gggtgacgag aatcgaactc gcgacaacag cttggaaggc
      661 tgtagtttta ccactaaact acacccgcat aaatactatc aataaaatgg cgcgagacgg
      721 aatcgaaccg ccgacacatg gagcttcaat ccattgctct accaactgag ctaccgagcc
      781 ttattgcggg agcaggattt gaacctacga ccttcgggtt atgagcccga cgagctaccg
      841 agctgctcca tcccgcgtta ataatataaa aggaggatgt gggattcgaa cccacgcacg
      901 cttttacacg cctgacggtt ttcaagaccg ttcccttcag ccggacttgg gtaatcctcc
      961 aatattcaaa tggaccttgt aggacttgaa cctacgacca ctcggttatg agccgagagc
     1021 tctaaccagc tgagctaaag gtccgacaag atcattatag cggcgaaggg gatcgaaccc
     1081 ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc catgaatcgg
     1141 gaagacagga ttcgaacctg cgacaccttg gtcccaaacc aagtactcta ccaagctgag
     1201 ctacttcccg agttaaatag aaaaatgcac cctagaggag tcgaacctct aaccgcctga
     1261 ttcgtagtca ggtactctat ccagttgagc taagggtgct ccatattatg ccgaggaccg
     1321 gaatcgaacc ggtacgatcg ttaccaatcg caggatttta agtcctgtgc gtctgccagt
     1381 tccgccaccc cggcctctct aagcgaacga cgggattcga acccgcgacc cccaccttgg
     1441 caaggtggtg ttctaccact gaactacgtt cgcactgttt tcttctatct aaaaatgccg
     1501 gctacatgac ttgaacacgc gaccctctga ttacaaatca gatgctctac caactgagct
     1561 aagccggctc atttgttata tcttaatgcg ggttaaggga cttgaacccc cacgccgtta
     1621 agcgccagat cctaaatctg gtgcgtctgc caattccgcc aaacccgcat atatgacccg
     1681 tactgggctc gaaccagtga cccattgatt aaaagtcaat tgctctacca actgagctaa
     1741 cgagtctaaa ataacttgcg ttaccttaaa cggtcccgac gggaatcgaa cccgcgatct
     1801 tcgccgtgac agggcgacgt gataaccgct acactacggg acct
//
LOCUS       DAVKXA010000104         1795 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKXA010000104 DAVKXA010000000
VERSION     DAVKXA010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.104"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            367..843
                     /locus_tag="VW883_002123"
     CDS             367..843
                     /locus_tag="VW883_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0275159.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            843..1604
                     /locus_tag="VW883_002124"
     CDS             843..1604
                     /locus_tag="VW883_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PezT"
                     /protein_id="HEV0275160.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT          660 a          238 c          349 g          548 t
ORIGIN      
        1 tcagtaaaaa caacacttta ttgaggtatt ggatacgctt tgctaatagc ctaataatca
       61 catgtggagt gttgctacaa cgaaaaaggt gataatcctt gatttcaagc tattttataa
      121 gcattttgtc tttgtagata aaggcaattt tgacaataaa aatcctaaaa ggtgaatcgt
      181 tatagatgta tttgtagata tcgtttgcgc atcgaaaaaa ttaatacaag aataaatatt
      241 tatggctctt taggtgactt ttatagaagt aaagtttagg atagaaaaac aagaaataac
      301 gcaccatttt tggtgcgtta tgctttttta tgctataatg gatttataaa aataaaggag
      361 tttgctatga ttggaaagaa cataaaatcc ttacgtaaaa cacatgactt aacacaacct
      421 gaatttgcac gaattatagg aatttctcga aatagcttga gtcgttatga aaatggaact
      481 agttcagtct ctacggaatt aattgacatc atttgtcaga agtttaatgt atcttatgtc
      541 gatattgtag gagaagataa aatgctcaat cctgttgaag attatgaatt gactttgaaa
      601 attgaaattg tgaaagaaag aggtgctaat ctattatctc gactctatcg ttatcaagat
      661 agtcagggaa ttagcattga tgatgaatct aatccttgga ttttaatgag tgatgatcta
      721 tctgacttga ttcagacaaa tatctattta gtagaaaatt ttgatgaaat agagagatat
      781 agcggctatt tggatggaat tgaacgtatg ttagagatat ctgaaaagcg gatggtagct
      841 taatggaaat ccaagattat actgatagtg aattcaaaca tgctttagca aggaatcttc
      901 gttcactgac aagaggaaaa aagtccagta aacaacctat agcgattttg cttggaggtc
      961 aaagtggtgc cggtaagact acaattcatc gtattaaaca gaaagaattt caaggaaata
     1021 ttgttatcat agatggtgat agttttcgtt ctcagcatcc acactattta gaactgcagc
     1081 aagaatatgg caaagacagt gtagaatata ccaaagattt tgcaggaaaa atggtagagt
     1141 ctttagtaac aaaattgagt agtttgagat acaatctttt gatagaggga actttacgaa
     1201 cagttgatgt tccaaagaaa acagcacaac tcttgaaaaa taagggatat gaagtacaat
     1261 tggccttaat tgcgacaaag cctgaattgt cgtatctaag tactcttatc cgttatgaag
     1321 aactgtacat tatcaatcca aatcaagcac gcgcaactcc aaaagaacat catgatttca
     1381 ttgtaaatca tctagttgat aatacacgac aattggaaga actggctatc tttgaaagaa
     1441 ttcaaattta ccaacgagat agaagttgtg tatatgattc aaaagaaaat acaacttcag
     1501 cagcagatgt tcttcaagag ttactgtttg gggagtggag tcaggtagag aaggagatgt
     1561 tgcaggtggg ggaaaagaga cttaatgaat tacttgaaaa ataaacaatt gatattttta
     1621 ggagagtaga aatgagaggg tttaataaca agataaagtc tgtttatcaa gaactaacaa
     1681 attccaaaga gaaattcggt agctttcaca agactttaat tcatttgcat acacctgttt
     1741 cttatgatta caagctattt tctaattgga ctgcaacgaa atatagaaaa attac
//
LOCUS       DAVKXA010000105         1736 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKXA010000105 DAVKXA010000000
VERSION     DAVKXA010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.105"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            18..1019
                     /locus_tag="VW883_002125"
     CDS             18..1019
                     /locus_tag="VW883_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0275161.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1231..1460
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT          578 a          232 c          352 g          574 t
ORIGIN      
        1 tgtaatagag gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg
       61 cacgtttatc aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg
      121 ttaaagaaga aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa
      181 atgcgtatgc aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa
      241 aaatcgactc ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt
      301 gtaaagaatt tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta
      361 attcaattat atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg
      421 tagatgatat cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg
      481 aatctcaaac gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata
      541 tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg ggaggagaat
      601 ctcatgttaa taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact
      661 ttatggattt aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa
      721 tgcagcactt gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg
      781 ttcagggctt gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta
      841 ttattggatt tgataatatt cctatttctc agtattatac tccagctttg tctacaattg
      901 ctcccaatta tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag
      961 gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt
     1021 attgtttaat tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt
     1081 tagcctccat tcagtttcta ttgagttgga tccaatttct aacaagtggg acatgttcat
     1141 gttcgatcta aggaagacat ggtcacattc gaatgatatt ttcaaaaaaa tcgtaaaaaa
     1201 gtcttgacaa agaaaaaaca aagtattaaa ataagttcaa caaatcagaa aagtaactat
     1261 ttttgatctt cagggagcct gtggtggttg tgaataggtg gttggaagta gtgaaagtgg
     1321 gctgattttg aaaatgaatt tgaaacaatg aaaattcggt gcgcacacct tacagtgcag
     1381 cttgttgtta aacaaggcag agatgtaaag ggatagtccc tttataattg aggtggcacc
     1441 gcgttaccaa cgccctcaca cggaagtata ttctgtgtgt gggctttttt ctatccgtcg
     1501 tttggtttat cttttattag ggccttaagt cgctttgatg aacttgagtt ctatctacag
     1561 ctccttgcct actactaaaa gcaaacaaaa aggctggact aatacgaaaa aagctagtaa
     1621 tactcaatga aaatcaaaga gcaaactaag aaactagccg caggttgctc aaaacactgt
     1681 tttgaggttg tggatagaac tgacgaagtc agctcaaaat actgttttga ggttgt
//
LOCUS       DAVKXA010000106         1696 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKXA010000106 DAVKXA010000000
VERSION     DAVKXA010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1696
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.106"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..1222
                     /gene="lanM"
                     /locus_tag="VW883_002126"
     CDS             <1..1222
                     /gene="lanM"
                     /locus_tag="VW883_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEV0275162.1"
                     /translation="YYNKLKPELWLSTATKIGDLIIDNSIEGVNEYGRKDLAWISVTM
                     QGFEEDVWLPSVLTNDLYSGNAGISLFLINLWNITGKKRFLEYAKKSVETSKVLLGNK
                     YIHSNHLVGAFTGVGGMIYSLAEIAHLTGDVKNKNFIKKSILSLDELILRDTSNDLIS
                     GNTGLLAVILKLVNSDSYYNTPDIKYVISKIVQKILHESKFVDGLRFWECMPNRNYVG
                     FSHGNAGIHSYLFKAMKYLGDSRAEEILQESLNYEKKCFSSHKNDWYKSKDEKQISYT
                     WCHGSPGILLSKLLLLSSGYNFDNLDNDIRLSIENTKAYGFGNNPTYCHGDLGNLEIL
                     NYASKLLHKKNLNNLCTNIYQELFDTVLVKEWDKKNLKSSNTYGLMVGLSGWGYSMLS
                     NYTDHSLNNFLWLD"
     gene            1292..1462
                     /locus_tag="VW883_002127"
     CDS             1292..1462
                     /locus_tag="VW883_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lichenicidin alpha family lanthipeptide"
                     /protein_id="HEV0275163.1"
                     /translation="MAQKDFPQKINSQLLEEISDNSAVGAGWAQLSFISEALGNKGAV
                     CTGTIECQNNCR"
     gene            1485..1676
                     /locus_tag="VW883_002128"
     CDS             1485..1676
                     /locus_tag="VW883_002128"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="HEV0275164.1"
                     /translation="MNNKFTGKINELELEQLVGDNQVVGGITPTIIPATISFVGVTFT
                     VTLNAGACPTSGCTKSCNK"
BASE COUNT          613 a          192 c          315 g          576 t
ORIGIN      
        1 atattataat aaattaaaac cagaattatg gttgtctact gctactaaaa ttggagattt
       61 gattattgat aattcaattg aaggagttaa tgagtacggt cgaaaagatt tggcctggat
      121 tagtgtaaca atgcagggtt ttgaagagga tgtttggtta ccttctgttt taacaaatga
      181 tttgtatagt gggaatgcag gaatttcgtt atttttaatc aatttatgga acataacagg
      241 taagaaaaga tttttagagt atgccaagaa atctgttgaa acctcaaagg tattattggg
      301 aaataagtac attcactcta atcatttagt aggggctttt acaggtgtag gagggatgat
      361 atattcactt gctgaaattg ctcatctcac tggagatgta aaaaataaaa attttattaa
      421 aaaatctatc ttaagtttag atgaactaat tttaagggat acttcaaatg atttaattag
      481 tgggaataca gggctattgg ctgtaatttt aaaacttgtt aattcagatt catattacaa
      541 cacacctgat attaaatatg ttatttccaa aatagttcaa aaaatattac atgaatcaaa
      601 gtttgtagac gggttaaggt tttgggaatg tatgccaaat agaaattatg ttggtttttc
      661 tcacggaaat gcaggtatcc attcttattt atttaaggca atgaaatatt tgggagatag
      721 tcgtgcagag gaaattttgc aagaatcatt gaactatgaa aaaaaatgct tctcttctca
      781 taaaaatgat tggtataaat ctaaagatga aaaacaaata tcttatacgt ggtgtcatgg
      841 atcacctggg atacttttaa gtaaattatt attgctttct tcaggatata attttgataa
      901 tttagataat gacattagac taagtattga gaacactaaa gcttatggat ttgggaataa
      961 tcctacatat tgtcacggtg atttaggaaa tttagaaata ttaaattatg cttctaaact
     1021 acttcataaa aagaatctaa ataatttatg tacaaatata tatcaggaac tatttgatac
     1081 tgttcttgtt aaagaatggg ataaaaaaaa tttaaaatct tcgaatacat acggtctaat
     1141 ggttggttta tcggggtggg gttactccat gttatcaaat tatacggatc actctttgaa
     1201 taactttcta tggttagatt gatacgtctc ttttttcaaa agcattattc tgggctatat
     1261 aaattaaaat tagttaggag agaatagtta gatggcacaa aaagattttc ctcaaaaaat
     1321 taacagtcag ttattagaag aaattagtga taacagtgca gttggagcgg gatgggcgca
     1381 gcttagtttt ataagtgaag ctcttggaaa taaaggtgca gtttgcacag gtacaattga
     1441 atgtcaaaat aattgtagat aataatattt agtggagaaa aataatgaat aataaattta
     1501 caggaaaaat taatgaatta gaactcgaac aattagttgg agataatcaa gttgtaggtg
     1561 gaataacccc tactattatt cccgctacaa tttcttttgt gggtgttaca tttaccgtaa
     1621 cattaaatgc tggtgcatgt ccaacttccg gatgtacaaa gagttgcaat aaataattaa
     1681 gtaacaacat ttttga
//
LOCUS       DAVKXA010000107         1410 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKXA010000107 DAVKXA010000000
VERSION     DAVKXA010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.107"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            169..924
                     /locus_tag="VW883_002129"
                     /pseudo
     CDS             169..924
                     /locus_tag="VW883_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(959..1168)
                     /locus_tag="VW883_002130"
                     /pseudo
     CDS             complement(959..1168)
                     /locus_tag="VW883_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1334..1407)
                     /locus_tag="VW883_002131"
     tRNA            complement(1334..1407)
                     /locus_tag="VW883_002131"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1371..1373),aa:Asn,seq:gtt)
BASE COUNT          482 a          276 c          223 g          429 t
ORIGIN      
        1 agataaaaat aggaaaagtt gacaaaatag aaacaaattt gctacctaaa tttcaaacaa
       61 ttaaagttct aaaaagaccg ccttaaaact tttgggtaaa tcctattaga actataatat
      121 ttttatatag gtattatggt tctgattttc tagtataaaa aaattcaaac tagaattctt
      181 cttagaaaag gccgttttaa gtgctatcat tgctcaaaaa tggaggttgc tgagacttct
      241 atcgtcaaga agaatcatca aattccttgt atcatcaacc aaaagattgc tcagaagcta
      301 attgaaaaga cttctatgac cgacattgat catcagttgt ctatttcaac ttcaactgtc
      361 attcgcaaga tcaatgattt tcactttgag catgattttt cgcgtcttcc tgagattatg
      421 tcctaggacg ttgaaacagt ctggggagtg actgtttcaa tcgggagata gagatgagct
      481 ttattgctca ggactttgat aagctcaata tcataactgt tcttgagagc agaacacaag
      541 ccatcatccg aaatcccatg aatacaaggc tatcaagcga tactgaaagc tcattcaaca
      601 agatagtcag aaactgagtg ataaagaaat tctagataaa cttttgagct attccgaaga
      661 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctttt tcagactctg
      721 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
      781 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
      841 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
      901 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
      961 aattgaaaca agaacaagac aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     1021 ttttgaggtg ctttttgata tgagcccatg ttttctcaat aggattgtac tcaggtgagt
     1081 agggaggaag atgtaaaagt ttatgcccaa actcttcgca taaaagttct agcttcccca
     1141 ttctgtggaa tcttgcattg tccataatat agtagattga aactagaata gtacacctct
     1201 acttctaaaa cattgttaga attcgatttt actgtcctaa tcgatttgtc ctattcttat
     1261 ttcattttac tataacacga aatagattat tattacataa caaaaaagag gtctaaacct
     1321 cttaactcaa ttactccgcc agtaggactc gaacctacga catcatgatt aacagtcatg
     1381 cgctactacc aactgagcta tggcggatta
//
LOCUS       DAVKXA010000108         1393 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKXA010000108 DAVKXA010000000
VERSION     DAVKXA010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.108"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(114..389)
                     /locus_tag="VW883_002132"
     CDS             complement(114..389)
                     /locus_tag="VW883_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0275165.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(495..1334)
                     /locus_tag="VW883_002133"
     CDS             complement(495..1334)
                     /locus_tag="VW883_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0275166.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
BASE COUNT          418 a          296 c          213 g          466 t
ORIGIN      
        1 acaatatttt cggaacattc aactttttaa ctctatttat tactagattt cataattaaa
       61 aaacctactg accaagctag aaagcttgat acaataggct ttttaaagac tgattattta
      121 acagcgtctt taagagcttt accagctttg aatgctggta ctttagaagc tgcaattgtc
      181 atttctttac cagtttgtgg gttgcgacct ttacgttctg cgcgctcacg aacttcaaag
      241 ttaccaaaac cgatcaattg aactttttca ccagctgcaa gatagtcagc tactgctgca
      301 aatacagctt caactgctgc tgctgagtct ttcttagtca attctgtagc ttctgctact
      361 ttagcgatca aatcttgttt gtttgccatg ttaatgattc ctccaaataa tttctaatta
      421 acaaatataa tcatatccta aaatcccttt taggtcaagt taaaaacgct atttcttccc
      481 attttattta ttttttagga gtggtaacgt atcaaaatag cccaagcgtt ctcacccgtg
      541 tgagtttgaa taatggaacc cgtttccaaa acagaaattg gcttttcaac ataagcttgt
      601 aagctttctt tcatctcttt tgcccaatca tcactaccag aatatgaaat tccaatctct
      661 gctacagcac gttcagaaag cgatgttatc aactcatcta accatttttt aaatgtttta
      721 gttccacgac ctttaaccat tggctgcaat tcatggtctt tcatttgcat gacagcacgg
      781 atattgagaa gagagctcaa caagccagtt acacggctaa ttcgtccacc tttgacaaga
      841 ttttccaaag ttgaaacacc aatataaagc tctgtatggt ttttaacctc ttctacatga
      901 gataaaattg cctccatatc tttaccttct tgagctaact tcgcagcctc aacaacttgg
      961 aatttcaggg cttggtcagt gaaggaacta tcaacaacag tcacatctgc agtagatagg
     1021 ctagcacctt ggcgtgctgc ttctaccgta cccgaaagag catgggacat atgaatagca
     1081 agaatctggc caccatcttt gcataggtct tcaaaaatct cagcaaagac acctacaggt
     1141 ggctgacttg ttttcggaag attcttactt tcttgcatca actgaagaaa tttaccttct
     1201 tctttcaaat ccgcatcaga ataaacaaca ttatcaatca ttacagataa tggaacaatt
     1261 gtaatatcta attgctttac tagttcaggt tcaatagtaa cagatgaatc ggttacaatc
     1321 ttaatttttg tcatagtatc aatctttcta ttttaggatt cagattggtt tccttacttc
     1381 taattatatc aaa
//
LOCUS       DAVKXA010000109         1379 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKXA010000109 DAVKXA010000000
VERSION     DAVKXA010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.109"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..635
                     /locus_tag="VW883_002134"
     CDS             <1..635
                     /locus_tag="VW883_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0275167.1"
                     /translation="KNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQIIKIATDK
                     NDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSSNLLNKGIE
                     AYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNECLNESISLL
                     QNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS"
     gene            672..1347
                     /locus_tag="VW883_002135"
                     /pseudo
     CDS             672..1347
                     /locus_tag="VW883_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921814.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          505 a          211 c          258 g          405 t
ORIGIN      
        1 agaaaaatgg agttcccctt tcagatgttt ggaatatacc atttcttaat ccaaaagcta
       61 aagaaagagt aggttatcct acacaaaaac ctattctgtt attagaacaa attataaaga
      121 ttgctactga taaaaatgat atagttttag acccgttctg tggaagtgga actactttag
      181 tagcctccaa gattttgaat agaaattata tggggattga tttatctgag gaagctatca
      241 atataactca gcaacgtctg gaaaatgtta taaaaacaag ttcaaattta ttgaataaag
      301 gaatcgaagc atatagaacc aaaactgagg aagaggaaaa cattcttaaa ttattacagg
      361 caaaaattgt tcaaagaaat aaaggaattg atggtttttt acctaaacat tttcaaaaaa
      421 aaccgatacc tataaaaatt caaaaaaata atgaatgtct gaatgagagt atctctttat
      481 tacagaatgc tataaactcc aaaaaacttg attttggagt agttataaaa actcattcag
      541 ataatttatt atttgatttt gatacgattc ctgaaaatat aatagtagtt gaccattttg
      601 aacttacaat cgaaaaatgg ttaagtaaaa gttaacagtt actatagttt gcaaattatt
      661 tacagaaaga acaagaattc ctaggagatt attctggcta tgtgcattgt gatatgttgc
      721 ggcagtaact taggacttta gtcctctagt tctgcctatg cgatagcagt ccaaggttta
      781 ggagcaaggc gacgctaagc ttggtaaact acgaaccgca gcaagcggat aaatcatcct
      841 taggagctaa aggtttagct tattgtgatc agttatttgc cttggaaaga gactgggagg
      901 acattgtcag ctgatgaacg actacagaaa cgtcaagaag agctccaacc cctaatggaa
      961 gacttctttg cttggtgccg tcgtcagtca gttttagcag gttcaaaact aggaagggca
     1021 attgaataca gcctcaagta taaagaaacc tttaagacta ttttaaaaga cggacatctg
     1081 gtcctttcca ataatctagc tgaacgcgcc attaaatcat tggttatggg acgtaaaaat
     1141 tggttgtttt ctcaaagttt tgaaggagct aaagcaagag ctattattat gaacttattg
     1201 gaaacagcta aacgtcatca actaaatagt gagaaatatc tatcctatct tctagaatgt
     1261 cttccaaacg aggaaactct cgtaaacaaa gaggttttag aggcttattt accatggact
     1321 aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat ccgtgagtt
//
LOCUS       DAVKXA010000110         1252 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKXA010000110 DAVKXA010000000
VERSION     DAVKXA010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.110"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..578)
                     /locus_tag="VW883_002136"
     CDS             complement(<1..578)
                     /locus_tag="VW883_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0275168.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHIL"
     gene            complement(612..782)
                     /locus_tag="VW883_002137"
     CDS             complement(612..782)
                     /locus_tag="VW883_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275169.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYAISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            complement(795..1241)
                     /locus_tag="VW883_002138"
     CDS             complement(795..1241)
                     /locus_tag="VW883_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0275170.1"
                     /translation="MNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTII
                     SEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQII
                     IAHRLSTIKDADIIFVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT          401 a          243 c          137 g          471 t
ORIGIN      
        1 ctaagaatat gacttgatat taaaaatgta ataccttttt tctcctgtag aaaacggatt
       61 aaacttctaa tttcaattac accctgtgga tcaagtccat tgattggttc atcccaaatt
      121 aatatttctg gactacctaa caatgatgca gctatactta gacgttgttt catgcccatt
      181 gaaaaatttt tcactttttt ctttttaaca tcttttaatc ctaccattga tagatattca
      241 ttaagtcttt cagtatctaa actaagccct ttcatatttg ctattaactt caaattttta
      301 taagcatcaa gatgaccata aaatgaaggt cccaaaacta atcctatcct agataatata
      361 ttttcggaat tctgttctac ggtttgatta aaaatagtta ttttcccaga atctggtttt
      421 aaaatcccta gaatcatttt gataattgta gtttttccag ccccatttgg tccaacaaaa
      481 ccatatactt ttcccttatt taaataaaat gaagtgttat gaataacttc aatatcttta
      541 aagctttttg ttagatttat aatttcaact atagccatct ctactcctta gtttacagca
      601 aaaaattatg cttaattctt attgtttttg taaaaaatca gcgaacccaa tactattcca
      661 ttcaacaaac ctaaagaaat agcatattca actggaaaat ctaaaaaaat tgcaaatact
      721 attccaatca tcacccctag tgaggctgct gttgaaatta catattcatt tactttcttc
      781 attttcttta cacctcattt cctttttgta tataagctgt agtactctcc accaagatcc
      841 attaagtact tatgatttcc tgactcaaca atcttaccac ctttcattac aaaaataata
      901 tccgcatcct taatcgttga caatctatga gctataatta tttgagtaca accctgactt
      961 tgtatatact ttgttattct ttcctcatta atagtgtcta atgcactagt tgcttcatct
     1021 aaaattacaa tactaggatt atttattaat gcacgtgcca gtgctatccg ttgcctttgc
     1081 ccacctgaaa tatttgaccc catctctgag atgatagtat taaatttcat cggcatagcc
     1141 atgatttcat catagatttg aactgcttta caaacttcct ctatcttttg tgaagtaact
     1201 tcgttcttta aagttatatt atcaagaata cttcggttca ataaaaatga at
//
LOCUS       DAVKXA010000111         1209 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKXA010000111 DAVKXA010000000
VERSION     DAVKXA010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.111"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            10..>1209
                     /gene="phtD"
                     /locus_tag="VW883_002139"
     CDS             10..>1209
                     /gene="phtD"
                     /locus_tag="VW883_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0275171.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFE"
BASE COUNT          384 a          258 c          257 g          310 t
ORIGIN      
        1 gaggaaagaa tgaaaattaa taaaaaatat ctagcaggtt cagtggcagt ccttgcccta
       61 agtgtttgtt cctatgagct tggacgttac caagctggtc aggataagaa agagtctaat
      121 cgagttgctt atatagatgg tgatcaggct ggtcaaaagg cagaaaactt gacaccagat
      181 gaagtcagta agagggaggg gatcaacgcc gaacaaatcg tcatcaagat tacggatcaa
      241 ggttatgtga cctctcatgg agaccattat cattactata atggcaaggt cccttatgat
      301 gccatcatca gtgaagagct cctcatgaaa gatccgaatt atcagttgaa ggattcagac
      361 attgtcaatg aaatcaaggg tggctatgtg attaaggtag atggaaaata ctatgtttac
      421 cttaaggatg cagctcatgc ggataatatt cggacaaaag aagagattaa acgtcagaag
      481 caggaacgca gtcataatca caactcaaga gcagataatg ctgttgctgc agccagagcc
      541 caaggacgtt atacaacgga tgatgggtat atcttcaatg cttctgatat cattgaagat
      601 actggtgatg cttatatcgt tcctcacggc gaccattacc attacattcc taagagtgat
      661 ttgtctgcca gtgaattagc tgctgcccaa gcctattgga atgggaagca gggatctcgt
      721 ccttcttcaa gttctagtca taatgcaaat ccagctcaac caagattgtc agagaaccac
      781 aatctgactg tcactccaac ttatcatcaa aatcaagggg aaaacatttc aagcctttta
      841 cgtgaattgt atgctaaacc cttatcagaa cgccatgtag aatctgatgg ccttattttc
      901 gacccagcgc aaatcacaag tcgaaccgcc aatggtgttg ctgtaccgca cggagaccat
      961 tatcacttta ttccttattc acaactgtca cctttggaag aaaaattggc tcgtattatt
     1021 ccccttcgtt atcgttcaaa ccattgggta ccagattcaa gaccagaaca accaagtcca
     1081 caatcgactc cggaacctag tccaagtccg caacctgcac caaatcctca accagctcca
     1141 agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg cgatggttat
     1201 gtctttgag
//
LOCUS       DAVKXA010000112         1203 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKXA010000112 DAVKXA010000000
VERSION     DAVKXA010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.112"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..448
                     /locus_tag="VW883_002140"
     CDS             <1..448
                     /locus_tag="VW883_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV0275172.1"
                     /translation="PVGKRDFNANMKSKLITFIQGLQNYNFVIQSCDFRKTMNQVNKG
                     DFVYTDPPYRITTAAYNENGAWTLKDDLDLFKYLDSINDKGAYFALSNVVIHNNKENK
                     ELMKWASKYNLHVLDYHYNNSNYQSKAKMSNTVEVLITNYNSKGDI"
     gene            445..>1203
                     /locus_tag="VW883_002141"
     CDS             445..>1203
                     /locus_tag="VW883_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HEV0275173.1"
                     /translation="MRLKESTSIFNMGDTSIRVKEVVPIYKQILKTLQKHNQSNQKWN
                     NESQASFYSSVLSDFAKAETEDGINLFGNLKRNEITGLDKRGRTLTNALVKIGFINYD
                     RKLSQVGLNYISETEQAFDKLEELFGLTIDNLVYFRQLLKLRIYDSNSDKYFYNFRFA
                     LAFLNRYSKVPVRDFLWIVESIKPNFSEEKIKVIIDNYQSVYDNNKTFEQYRDEEFAN
                     HILIPERVDEARKMFSIKNFSDENFKKLFPNRKNS"
BASE COUNT          443 a          149 c          208 g          403 t
ORIGIN      
        1 tcctgtaggt aagcgtgatt ttaacgctaa tatgaaatct aaactaatta cgttcattca
       61 aggtttacaa aattacaatt ttgttatcca atcttgtgat tttcgtaaaa ctatgaatca
      121 agtaaataaa ggagattttg tatatacaga tcctccttat cgcattacta ctgccgctta
      181 caatgaaaat ggtgcgtgga cattaaagga tgatttggat ttgtttaagt atttagatag
      241 cataaacgat aagggagctt attttgctct ttctaatgtt gtcattcata acaataaaga
      301 aaataaagaa ttgatgaaat gggcttcaaa gtataattta catgtattag attaccatta
      361 caataatagt aattatcagt ctaaggcgaa aatgagtaat actgttgaag tcttgattac
      421 aaactataat tcgaaaggtg atatatgagg ctaaaagagt caacaagcat ttttaatatg
      481 ggtgatacga gtattcgtgt taaagaagtt gtccctatct acaaacagat tttaaaaact
      541 cttcaaaagc ataatcagtc aaatcagaaa tggaacaatg agagtcaagc aagtttttat
      601 tcatcagttt taagcgattt tgcaaaagct gaaacagagg atggaattaa cctttttggg
      661 aatttgaaga gaaatgaaat aactggttta gacaaaagag ggagaacttt aacaaatgct
      721 cttgtcaaga ttggttttat taactatgat agaaaattat ctcaagttgg gctgaattat
      781 atttctgaaa cagagcaagc ttttgataaa ttagaagaac tttttggttt aacaattgat
      841 aatcttgttt attttaggca attattgaag cttcgtatat atgatagtaa ctctgataaa
      901 tacttctata atttccgttt tgctcttgct tttttgaaca gatatagcaa agttcctgtt
      961 agagattttc tatggatagt ggaaagcatt aagccaaact tttcagaaga aaaaatcaaa
     1021 gtgattatcg ataattacca atctgtttat gataacaata aaacttttga acagtataga
     1081 gatgaagagt tcgctaatca tatattgatt cctgaaagag tggatgaagc tcgcaaaatg
     1141 tttagtatta aaaatttttc ggatgaaaac ttcaaaaaac tttttccaaa tcgaaagaat
     1201 agt
//
LOCUS       DAVKXA010000113         1170 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKXA010000113 DAVKXA010000000
VERSION     DAVKXA010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.113"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(188..259)
                     /gene="shp3"
                     /locus_tag="VW883_002142"
     CDS             complement(188..259)
                     /gene="shp3"
                     /locus_tag="VW883_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEV0275174.1"
                     /translation="MKKISKFLPILVLVMDIIIIVGG"
     gene            339..>1170
                     /locus_tag="VW883_002143"
     CDS             339..>1170
                     /locus_tag="VW883_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV0275175.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISHFERGESEIS
                     CIRLINILDKLHITLDEFLVLYNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     F"
BASE COUNT          419 a          202 c          151 g          398 t
ORIGIN      
        1 agaaatttaa aagtttctcg atataattct ctcctaaatg ctttgttaac tccttttcaa
       61 acgtttctaa actatactcc ggaaaataat ttaaccaata attaatcata ctatctttca
      121 tcgtatcctc caaccagtac taagtcttta gatgatatct aaagacttag gtgtacacct
      181 aagcatctta cccaccaaca atgatgataa tatccatcac caaaaccaaa atcggtaaaa
      241 attttgaaat tttcttcata cttggacttc ctttccgttt ttatttattg tacaataaat
      301 aaaaacggat ttaatttttg ttgggaaaat gggaaattat gaaatcaaaa cttggcatca
      361 cacttagaaa agttcgtaaa ggaaaacaaa ttagtctatg ctctgtagca gatgaacatc
      421 tttcaaaatc acaaatatct cattttgaac gtggggagtc agagatatct tgtattcgac
      481 taatcaatat tttagacaaa ttacatatta ctttggatga gttccttgtt ttatacaatg
      541 acgactatac cagttccgaa tcatttgcta atctagtaca gtacattcgt aagcaatatt
      601 catcacaaag tatcaataat atagcatgtc tactttctga tacttctgat tacactctaa
      661 attcttttga gaaaacaatg gtaaaatcta ttttacacac aatggattcg aacatcattc
      721 catcagatga agagcttctt catctgacag actatctttt caaagttgaa aaatggggct
      781 attatgaaat cattttatta ggtaactgtg tacgcacaat taactacaac tcctacttct
      841 tattaactaa agagatgtta aataactata tttactcatc tctgaataaa actaataagc
      901 agattgtctc tcagcttgct attaattgct tcattctaag cattgataag gaagaatttt
      961 ctaattgctc ctatttaatt agtaagataa agacattgtt ggacaatgaa ctaaactttt
     1021 atgaacaaac agtttttctc tatgcaactg gttactttga atttaaacgt tgccaatcaa
     1081 ccagtggaat tgaaaaaatg aaacaagcca tacaagtctt cgatatttta ggagaagata
     1141 agttaaaatt acactatact gaccatttta
//
LOCUS       DAVKXA010000114         1088 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKXA010000114 DAVKXA010000000
VERSION     DAVKXA010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.114"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            21..>1088
                     /gene="pcpA"
                     /locus_tag="VW883_002144"
     CDS             21..>1088
                     /gene="pcpA"
                     /locus_tag="VW883_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0275176.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGK"
BASE COUNT          425 a          153 c          177 g          333 t
ORIGIN      
        1 aaatatgtaa ggaaatttaa atgaaaaaaa ctacaatatt atcattaact acagctgcgg
       61 ttattttagc agcatatgtc cctaatgaac caatcctagc agatactcct agttcggaag
      121 taatcaaaga gactaaagtt ggaagtatta ttcaacaaaa taatatcaaa tataaggttc
      181 taactgtaga aggtaacata ggaactgttc aagtgggtaa tggagttact cctgtagagt
      241 ttgaagctgg tcaagatgga aaaccattca cgattcctac aaaaatcaca gtaggtgata
      301 aagtatttac cgttactgaa gtagctagtc aagcttttag ttattatcca gatgaaacag
      361 gtagaattgt ctactatcct agctctatta ctatcccatc aagcataaaa aaaatacaaa
      421 aaaaaggctt ccatggaagt aaagctaaaa ctattatttt tgacaaaggc agtcagctgg
      481 agaaaattga agatagagct tttgattttt ctgaattaga agagattgaa ttgcctgcat
      541 ctctagaata tattggaaca agtgcatttt cttttagtca aaaattgaaa aagctaacct
      601 tttcctcaag ttcaaaatta gaattaatat cacatgaggc ttttgctaat ttatcaaatt
      661 tagagaaact aacattacca aaatcggtta aaacattagg aagtaatcta tttagactca
      721 ctactagctt aaaacatgtt gatgttgaag aaggaaatga atcgtttgcc tcagttgatg
      781 gtgttttgtt ttcaaaagat aaaacccaat taatttatta tccaagtcaa aaaaatgacg
      841 aaagttataa aacgcctaag gagacaaaag aacttgcatc atattcattt aataaaaatt
      901 cttacttgaa aaaactcgaa ttgaatgaag gtttagaaaa aatcggtact tttgcatttg
      961 cagatgcgat taaacttgaa gaaattagct taccaaatag tttagaaact attgaacgtt
     1021 tagcctttta cggtaattta gaattaaaag aacttatatt accagataat gttaaaaatt
     1081 ttggtaaa
//
LOCUS       DAVKXA010000115         1066 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVKXA010000115 DAVKXA010000000
VERSION     DAVKXA010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.115"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1..947
                     /locus_tag="VW883_002145"
                     /pseudo
     CDS             1..947
                     /locus_tag="VW883_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            940..>1066
                     /locus_tag="VW883_002146"
     CDS             940..>1066
                     /locus_tag="VW883_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0275177.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVII"
BASE COUNT          398 a          100 c          208 g          360 t
ORIGIN      
        1 ttcaaataat tttgaaactg ccttacacgt taaaaatatt ttaaaattat taaaaatccg
       61 acttatacac tgtcatggct actcaactaa ttatttttta tatatgttaa aaaaacttga
      121 caagaatgga tttggaaagg ttaagacagt gataacatgc catggatggg ttgaatataa
      181 cttaaaaaag aaattcttga cttattttga tttttggaca tattctatgg gagatgcttt
      241 tatttgtgta tctgaaacta tgaaaaaaag attggagagt ataataaaaa aataagaaga
      301 tagttgcaat aaataacgga attaatgtat caaatagcga tttagatgta gtaggtgttc
      361 aagactttaa aaaagaattt tgtattccaa ataacaaaaa aatcatttgt tatgttggaa
      421 ggttggatcc agaaaaaagg ccggatagat tccttgaatt tgcagaaaaa ttatttttag
      481 tcagagaaga tgtgattttt attatggctg gaaatggtag tatgtgggct gctttgaaag
      541 aaaaaatttg ccatttgaaa tgtagagata atttcaggtt acttggtgaa atctatccag
      601 ctactatagt ttaccaaata tcggatttat tgtatattcc ttatgataca gaaggaatac
      661 ctatgtgtgt tttagagtca atgtcacaag gaactccggt tttagctagt aatgttggcg
      721 ggttaagtga aattattgaa catagggttg atggattttt atttgagaag gaagatgttg
      781 agggagtgtg tgcttgtgct aattttttac tcaatgattc tgagtatttg aaatatatag
      841 gtgagaatag taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg tttgtagaaa
      901 ccatgagagt atatgatgaa ttattagaga agagtagtca tggataggaa tatagatcaa
      961 gaattagtaa gtattataat accaacacat aataggtatg aatctctgat tagagctgtg
     1021 aaaagttgtt tacatcaaag ttataaaaat atcgaagtta taatta
//
LOCUS       DAVKXA010000116         1039 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVKXA010000116 DAVKXA010000000
VERSION     DAVKXA010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.116"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..109)
                     /locus_tag="VW883_002147"
     CDS             complement(<1..109)
                     /locus_tag="VW883_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV0275178.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKIN"
     gene            complement(122..871)
                     /locus_tag="VW883_002148"
     CDS             complement(122..871)
                     /locus_tag="VW883_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0275179.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          362 a          202 c          109 g          366 t
ORIGIN      
        1 tatttatttt tacagaatct atatcatatg caacaacttt atatttagat gcaaatagta
       61 acgcgtaggc cagcccaaca tgccccaaac caattactgc tatattcata aaactacttc
      121 cttatttctt aatccaaaat ctaatagaat aagctgcccc attccttaaa tacaactctt
      181 taatattgtt taaaagtttt tcaactgatt tccagattat caaaatctga gatttatagc
      241 acaatattga tgatattcta tcaatataat gtttttcatc aagttcctct tgatacattt
      301 ttaattcttt agtttttccc atataactaa ccatactact atcacttaca tatgggaagt
      361 cctcataata tattacttta taacgcataa attcaagcgc ccttccaata ctattcacaa
      421 aaacatgatc aacatggtca ccaagtgaaa gcggacaata tacgacacat ttgtcgtcta
      481 aatgcattaa cagctctttt atgatatcat tctttaatgt gtcctcattt tttaattcac
      541 tatagatatg acggtataga aaattgccat ttctatcttt cctatagaga cattcatagt
      601 acgataagtg tctaaaatca cattgtagac gttcacaagc taacctgtct tctttcttcc
      661 tttcttcaat cggatatttc ccaaggttac acaacttatg aaattgctta gcagagggct
      721 gtagctgttg gctcaaaggg taaccagaaa atatagtaat aacaagtaca atttctcctt
      781 ctgaagttaa ttttgaaata taatcaccac aggaaaaaat tgcgtcatct aaatgtggag
      841 ataaaaagat atacttagta ttgttactca taaccattcc ctctacaatt tatctaaaaa
      901 ctcactaagt gtctgattaa attccacatc atcaaaaaaa ttcaccttat tcttaataat
      961 gaatatttcg ttaaataaac atatatataa atatttcaat atcctttcaa tatcatcctc
     1021 taaattctcc tcaatattt
//
LOCUS       DAVKXA010000117          937 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVKXA010000117 DAVKXA010000000
VERSION     DAVKXA010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.117"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            105..584
                     /locus_tag="VW883_002149"
     CDS             105..584
                     /locus_tag="VW883_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0275180.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VW883_002150"
     tRNA            678..749
                     /locus_tag="VW883_002150"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
BASE COUNT          349 a          133 c          217 g          238 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc gtcaggacca cttgatgaaa
      781 aaaagtttaa aaaaacttaa aaatcttcaa aaaagtgttg acaagcgaaa gcagttgtga
      841 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
      901 agacgaacca atgtgcaggg cgctacaaca taagttg
//
LOCUS       DAVKXA010000118          833 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVKXA010000118 DAVKXA010000000
VERSION     DAVKXA010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.118"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..115)
                     /locus_tag="VW883_002151"
     CDS             complement(<1..115)
                     /locus_tag="VW883_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0275181.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKNTDST"
     gene            complement(118..348)
                     /gene="blpU"
                     /locus_tag="VW883_002152"
     CDS             complement(118..348)
                     /gene="blpU"
                     /locus_tag="VW883_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0275182.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(417..686)
                     /gene="blpJ"
                     /locus_tag="VW883_002153"
     CDS             complement(417..686)
                     /gene="blpJ"
                     /locus_tag="VW883_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV0275183.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
BASE COUNT          261 a          205 c           97 g          270 t
ORIGIN      
        1 gggtactatc tgtattcttt ttgggaaatt ttgaaaatat ttttctaatt aaattatcca
       61 tataaggacc aaatatacca actactaaac caataataaa acttttaaaa tccataatta
      121 ccaccaacat gttgctgcat aggctacacc tccaagtata gctccacccg cagcaccagt
      181 tgctgcacct tgccatgttc ctgttttaat gcctagttga agacctcttg ctgctgctcc
      241 tccaacacct gctttggcaa aatctcccca attgcatccg ccaccttcaa cgcaagcaag
      301 catttcagta tccataacag aaaattgtga catcattttt gtatccatga caaatactcc
      361 ttttttaaaa aactaaaata aatcagaata gaatcctcat aattttacta taagtcttac
      421 caacttagtc ccaatttatc accaaccata cctcctaagc atgttaatcc acccccaatt
      481 gcaccaatgt gtgctccaac aaatgcacca gcaagtccag ctactcctaa agtggccaaa
      541 cctgctccag ttccaccagt tataattccc gtagtgactc ctgtaatcag tgcattttga
      601 caatcagtgg agctataccc cccttcaact ttcgcaagca tttcagtatc cataacctct
      661 aactgtgaca acatttttgt attcatgatg aatacctcct ttttattttc aatttgttac
      721 caaagtctta aattcaataa acaaatagat tttttatagt atctttttga ttttcttaaa
      781 aaagtatata cgtctactat cttcttaaag gtagcagtac ctatttttta gtc
//
LOCUS       DAVKXA010000119          802 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVKXA010000119 DAVKXA010000000
VERSION     DAVKXA010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.119"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..>802
                     /locus_tag="VW883_002154"
     CDS             <1..>802
                     /locus_tag="VW883_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV0275184.1"
                     /translation="INQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSR
                     LPKIMSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKI
                     ITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAI
                     KRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHF
                     QNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNA"
BASE COUNT          254 a          168 c          125 g          255 t
ORIGIN      
        1 tcatcaacca aaaaattgct caaaagttaa ttgaaaaaat ttctatgact gatattgccc
       61 atcagctggc catttcaact tcaactgtca ttcgcaagct caatgacttt cactttgagc
      121 atgatttttc tcggcttcca aagattatgt cttgggatga gtatgccttc actaagggaa
      181 agatgagttt cattgcgcaa gattttgata atcttaatat tatcactgtt cttgaaggca
      241 gaacacaagc tgtcatccga aatcactttc ttcgctacga tagagccgtt cgttgtcaag
      301 tgaaaatcat tacgatggat atgtttagtc cttactatga cttggctaaa cagctttttc
      361 cgtgtgctaa aatcgttcta gatcgtttcc atattatcca acatctcagc cgtgccatga
      421 gtcgttttcg tgttcaaatt atgaatcagt ttgaacgaaa atctcatgaa tacaaggcta
      481 tcaaacgtta ctggaaactc atccaacagg atagtcgtaa attgagcgat aaacgttttt
      541 atcgccctac ttttcgcatg cacttaacaa ataaagaaat tcttgacaag attttaagct
      601 attcagaaga cttgaaacac cactatcaga tctatcaact cttacttttt cactttcaga
      661 acaaagaccc tgagaaattt ttcggactca ttgaggacaa tctgaagcag gttcatccta
      721 tttttcagac tgtctttaaa acctttctaa agaacaaaga aaaaatcgtc aacgctcttc
      781 aattacctta ttccaacgca aa
//
LOCUS       DAVKXA010000120          700 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVKXA010000120 DAVKXA010000000
VERSION     DAVKXA010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.120"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..>700
                     /locus_tag="VW883_002155"
     CDS             <1..>700
                     /locus_tag="VW883_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275185.1"
                     /translation="VTAENIRQSVKRLETDTQNKLNQKLSQAEFEVRAGSIRQEILNA
                     TKDKASKSELTQTAEELSSKIASVQASGRNLFLNSLFKQDISKTGIWTTSTYTATIDS
                     ESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKANK
                     NGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGTVW
                     IWMPKFEISDVDTSY"
BASE COUNT          238 a          127 c          163 g          172 t
ORIGIN      
        1 gtgactgctg aaaatatccg gcaatctgtg aagaggcttg agacagacac gcagaacaag
       61 ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ctggctctat ccgtcaggaa
      121 atcctgaatg caaccaagga taaagccagc aagtcagaac tcacgcagac agctgaggag
      181 ctctctagta agatagcgag tgtgcaggca tccggtcgaa atctattctt gaactcacta
      241 ttcaagcagg atatttcaaa aacaggaatt tggacaacga gtacatatac ggctactatc
      301 gatagcgaaa gtaagtatct tggacacaag gctcttaaaa ttataggtct gaatccatct
      361 ggccgtgatg gagggaatcc caaggttact tatccagctc tgggtcaatt cgggaaagta
      421 attcccggaa gtacgactaa tcaagatgta accattagtt tttatgctaa ggcaaataaa
      481 aatggaataa tgctaagatc tcgattaggg aatatcggat ataaaactgg aaatgtgaca
      541 ttgtcgacag aaattaaacg atatgttgtc catattccaa aaggttggac aaacgaatcc
      601 aagcagacca caaatgaatg gttgttcaat ttcaaccagg aaggaaccgt ttggatttgg
      661 atgccgaagt ttgaaataag cgatgtagat acttcttatt
//
LOCUS       DAVKXA010000121          662 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVKXA010000121 DAVKXA010000000
VERSION     DAVKXA010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.121"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..>662
                     /locus_tag="VW883_002156"
     CDS             <1..>662
                     /locus_tag="VW883_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0275186.1"
                     /translation="EALSRTKNELSGVKSAQATYEETTTRRLSELTNLANGKASKSEL
                     TQTAEELSSKIASVQVGGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVSDSPV
                     TGFDKAIRLTSSNARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNS
                     GISPIFTLKDENWTKLSFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLAT
                     SS"
BASE COUNT          202 a          128 c          179 g          153 t
ORIGIN      
        1 tgaagcactt agccggacta aaaatgaact gtctggcgtg aagtcagcgc aagcgacgta
       61 tgaggagacg acgactcgta gactgtcaga actgaccaac ttggccaatg gtaaagccag
      121 caagtcagaa ctcacgcaga cagctgagga gctctctagt aagatagcga gtgtgcaggt
      181 cgggggtagg aattatatcc ggggtacaaa gcgcatgatg ctagccagag gattgtgggc
      241 atcaggtact tttagaccgt caggcgctgg gacggcaaag acgattgatg tatcagacag
      301 tccagtaact ggctttgata aagcgatacg attgacctca agcaatgcta gagaccaaat
      361 aggtattgct caagatggat tttatatctc gcaaggcaca tacacgatgt cttgttgggt
      421 caaaggcaga agaggtcaaa aggtcaagct acaaacttat tggcaagtca atgataattc
      481 gggtatttcg cccatcttta cattaaagga tgaaaattgg acaaagctat cgtttactag
      541 cgctagaaat agggctggag tcgcatcaat tggctatgtg tatctcgtaa atgctgaagt
      601 cggagaatat ttagatgttc ttgcgcccca gctggaagac ggaagtttgg caacaagctc
      661 aa
//
LOCUS       DAVKXA010000122          591 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVKXA010000122 DAVKXA010000000
VERSION     DAVKXA010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.122"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(213..509)
                     /locus_tag="VW883_002157"
     CDS             complement(213..509)
                     /locus_tag="VW883_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV0275187.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
BASE COUNT          214 a          107 c           76 g          194 t
ORIGIN      
        1 ttactttgga taggcagttt catattataa cgattcaaag tagcgtaatc tactaccaaa
       61 aaaagtaaaa ataatttccc ttgaaaagga agatagcttt taaaatagat tgacaaactt
      121 atgataacaa aaaacaaaag ggttatccca ataaaattaa gataacctaa aatactttca
      181 cattcttttt tagaaagtat tttcatctag ttctaccata gagctgcttt agcagcacct
      241 ttctttttca atatataaag aactgttgct gcaatacccg aaccaataga acctactcct
      301 gtgattgcac ctacaattga aattactgct gtaactgtac tataagcact aatcaaattg
      361 actacagtag cagcagcttt tgtcgaaatt cctaatgtcc cagccaacat aggaaaagaa
      421 acaacaccta agcttaacca actaatgact gctaacattg ctgaaacaat aagaaattta
      481 ttatgaaatt ccattctttt agatttcatt ttagtgtact ccttttgtat attatgtatg
      541 ttttattgag agttaattcg cacatgttgt attcctaact ctcttcaaat g
//
LOCUS       DAVKXA010000123          517 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVKXA010000123 DAVKXA010000000
VERSION     DAVKXA010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.123"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..409)
                     /locus_tag="VW883_002158"
     CDS             complement(<1..409)
                     /locus_tag="VW883_002158"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0275188.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIK"
BASE COUNT          214 a           87 c           58 g          158 t
ORIGIN      
        1 tttttatata aataagtata tttttaattc ccctatcctt caataatcgg tataaaagat
       61 actgactcat accttgatac caaataaaat tcggtatttc aataagagca tgaggtaata
      121 ttccttttat tgtagctact attccaatca tctgaccaga tatacccaat tgtattccta
      181 aagatagcaa atcaaaaagt tgcaataagg gcgaaatcgg aaaacagaat agatatagca
      241 aaaaatttgt agaatttgcc tgtaaaactg tcaatgtaaa ttgtaattcc agtttcggag
      301 gtatagtagc aaaagtctca ttttttaata taaagcttaa aagtaaacct agtaaaaaac
      361 agactataca aaataacaca tagtaaatca gaaaaccact ttttctcatc taatgccccc
      421 tactaaaatt acaaatatta tcagaaaaca atataaaacc agaaaactcc atctcaataa
      481 actaactgta cctttaatta aaaatagagc tttctta
//
LOCUS       DAVKXA010000124          513 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVKXA010000124 DAVKXA010000000
VERSION     DAVKXA010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.124"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            22..>513
                     /locus_tag="VW883_002159"
     CDS             22..>513
                     /locus_tag="VW883_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0275189.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKG"
BASE COUNT          178 a          116 c           73 g          146 t
ORIGIN      
        1 caactcatta gaaagaatca tatggaacaa ttacatttta tcacaaaatt actagacatt
       61 aaagacccta atatccagat tttagacatc atcaataagg atacacacaa ggaaatcatc
      121 gccaaactgg actacgacgc cccatcttgc cctgagtgcg gaaaccaatt gaagaaatat
      181 gactttcaaa aaccgtctaa gatcccttac ctcgaaacaa ctggtatgcc ttctagaatt
      241 ctccttagaa aacgccgttt caagtgctat cactgttcaa aaatgatggt cgctgaaact
      301 tctatcgtca agaagaatca ccaaatccct cgtatcatca accaaaaaat tgctcaaaag
      361 ttaattgaaa agatttctat gactgatatt gcccatcagc tttccatctc aacttcaact
      421 gtcattcgaa agctcaatga cttccacttt aaacatgatt tttcttgtct tcctgagatt
      481 atgtcttggg atgagtatgc ttttacaaaa gga
//
LOCUS       DAVKXA010000125          476 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVKXA010000125 DAVKXA010000000
VERSION     DAVKXA010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.125"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            1..190
                     /locus_tag="VW883_002160"
                     /pseudo
     CDS             1..190
                     /locus_tag="VW883_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197307.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            200..>476
                     /locus_tag="VW883_002161"
     CDS             200..>476
                     /locus_tag="VW883_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0275190.1"
                     /translation="MAAGYLNRVNDIWLENEENVENGLKKCSLEGRIDIKDLSFSYSK
                     DSAPVIENLNLTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKIL"
BASE COUNT          166 a           59 c           86 g          165 t
ORIGIN      
        1 acgaagtatt gtgcatattt tatacaattc agctactaat gtatttcaat tgttcgctcc
       61 tataattata ttgatttttg gacttgataa tgttttaaat ggaaaaattt tattgggtga
      121 ggttgtcgca tttcaaacca tggcatcaat tttatttagt tcagaaatct caatatttaa
      181 tgcttatacg cagtatattt tggcagcagg atacttaaat agagtaaatg atatctggct
      241 tgaaaatgaa gagaatgttg aaaatggtct taaaaagtgt tctttagaag gtagaataga
      301 tattaaggac ctatctttct cttattccaa agactcagct cctgtaatag aaaatttaaa
      361 tttgactatt gagccaggac agagaattgc actagtcggt caatcggggt caggaaaaag
      421 tacgttatca aaaatactat caggattata taagattgat acaggaaaaa ttttat
//
LOCUS       DAVKXA010000126          461 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVKXA010000126 DAVKXA010000000
VERSION     DAVKXA010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.126"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            <1..>461
                     /locus_tag="VW883_002162"
     CDS             <1..>461
                     /locus_tag="VW883_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0275191.1"
                     /translation="PAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNK
                     AYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPER
                     LGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMT"
BASE COUNT          151 a           92 c           99 g          119 t
ORIGIN      
        1 tcccagccaa ggatctttca gcagaaacag cagcaggcat tgatagcaaa ctggccaagc
       61 aggaaagttt atctcataag ctaggagcta agaaaactga cctcccatct agtgatcgag
      121 aattttacaa taaggcttat gacttactag caagaattca ccaagattta cttgataata
      181 aaggtcgaca agttgatttt gaggctttgg ataacctgtt ggaacgactc aaggatgtct
      241 caagtgataa agtcaagtta gtggatgata ttcttgcctt cttagctccg attcgtcatc
      301 cagaacgttt aggaaaacca aatgcgcaaa ttacctacac tgatgatgag attcaagtag
      361 ccaagttggc aggcaagtac acaacagaag acggttatat ctttgatcct cgtgatataa
      421 ccagtgatga gggggatgcc tatgtaactc cacatatgac c
//
LOCUS       DAVKXA010000127          430 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00054633
            SAMN33606941-rid17953483.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVKXA010000127 DAVKXA010000000
VERSION     DAVKXA010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606941
            Sequence Read Archive: SRR23726234
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722111.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722111.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 01:56:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,163
            CDSs (total)                      :: 2,115
            Genes (coding)                    :: 1,980
            CDSs (with protein)               :: 1,980
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 62 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 45 of 135
            Pseudo Genes (multiple problems)  :: 31 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606941-rid17953483.denovo.127"
                     /strain="AUSMDU00054633"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST17520"
     gene            complement(<1..>430)
                     /locus_tag="VW883_002163"
     CDS             complement(<1..>430)
                     /locus_tag="VW883_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEV0275192.1"
                     /translation="DTEECMNDLDVKGFYQRIGELLGILYSLNSVDFHYENIIAKGAY
                     PVPIDLETLIHPQIVDRNNDLSAFKKASKKFESSVITTGLLPIFLKGNEVGGVSMNSE
                     QISTFKTDYIKDTNSDNIHIEREYYVISPKNNNPIINGKIV"
BASE COUNT          141 a           76 c           52 g          161 t
ORIGIN      
        1 acaatcttac cattgataat aggattgttg tttttaggag aaatgacata atactctctc
       61 tcaatatgaa tattatcgct gttagtatcc ttgatatagt cagttttaaa ggttgatatt
      121 tgctcactat tcatactaac accaccaact tcatttcctt ttaaaaaaat gggtaaaagc
      181 cctgtagtta ttactgagct ttcaaatttt ttagaagctt ttttgaatgc tgataaatca
      241 ttatttctat ccactatctg aggatggatt aatgtttcta aatcaattgg aactggataa
      301 gctcctttcg caataatgtt ttcataatga aaatctacag aattcaaaga ataaagtatt
      361 cccaacaatt ctcctattct ttgataaaac ccctttacat ccaaatcatt catacattct
      421 tctgtatcta
//
